NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2071063243|ref|NP_001382541|]
View 

protein FAM185A [Rattus norvegicus]

Protein Classification

DUF4097 family beta strand repeat-containing protein( domain architecture ID 1903587)

DUF4097 family beta strand repeat-containing protein similar to Homo sapiens protein FAM185A

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
YvlB super family cl43909
Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function ...
94-286 2.76e-04

Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function unknown];


The actual alignment was detected with superfamily member COG3595:

Pssm-ID: 442814 [Multi-domain]  Cd Length: 254  Bit Score: 42.16  E-value: 2.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071063243  94 VGSGTRGLDSLQVKYDAALQEMAILSDDIDPEASVEVNAPVKFDLNIESSGAGSVSVQNIECDSCKIDTEQGTSILQSVK 173
Cdd:COG3595     5 SAEIAAAVSVIAVVAGSIVVGLKTSRGSVDASSGGSVRRTVALGVDTGAALGGVDGVGGNGLAGASYLRVTSSGDVRVSG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071063243 174 SQKLHVNTKGGDVVcLGTIYGNIDIHASDKStVTIDKLQGSCVNISTEDGLLQAKYLYTDSSFVSSAAGDIALGNIHGNI 253
Cdd:COG3595    85 VDDVSVKTSSGDVT-VEDLSGDLTVKTVSGD-IELSGLTGDEVELETVSGDITVKDGVGGDVEAKTVSGDITVDGASGSV 162
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2071063243 254 VLESKMGNISVD---SSCGCLKASSDQGAIDVYISQ 286
Cdd:COG3595   163 EAKTVSGDIRLTlegAVAGRVKLKTVSGDVEVGLPE 198
 
Name Accession Description Interval E-value
YvlB COG3595
Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function ...
94-286 2.76e-04

Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function unknown];


Pssm-ID: 442814 [Multi-domain]  Cd Length: 254  Bit Score: 42.16  E-value: 2.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071063243  94 VGSGTRGLDSLQVKYDAALQEMAILSDDIDPEASVEVNAPVKFDLNIESSGAGSVSVQNIECDSCKIDTEQGTSILQSVK 173
Cdd:COG3595     5 SAEIAAAVSVIAVVAGSIVVGLKTSRGSVDASSGGSVRRTVALGVDTGAALGGVDGVGGNGLAGASYLRVTSSGDVRVSG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071063243 174 SQKLHVNTKGGDVVcLGTIYGNIDIHASDKStVTIDKLQGSCVNISTEDGLLQAKYLYTDSSFVSSAAGDIALGNIHGNI 253
Cdd:COG3595    85 VDDVSVKTSSGDVT-VEDLSGDLTVKTVSGD-IELSGLTGDEVELETVSGDITVKDGVGGDVEAKTVSGDITVDGASGSV 162
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2071063243 254 VLESKMGNISVD---SSCGCLKASSDQGAIDVYISQ 286
Cdd:COG3595   163 EAKTVSGDIRLTlegAVAGRVKLKTVSGDVEVGLPE 198
DUF4097 pfam13349
Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a ...
128-256 3.75e-04

Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.


Pssm-ID: 433135 [Multi-domain]  Cd Length: 246  Bit Score: 41.54  E-value: 3.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071063243 128 VEVNAPVKFDLNIESSGAGSVSVQNIECDSCKIDTEQG----------------TS---ILQSVKSQKLHVNTKGGDV-V 187
Cdd:pfam13349  89 ISVSDNLALKDVILSSNSGDITLKNVSAENLTIKSTSGdvsidgssakksklitTSgdiDLNNVSGKDLDLKSTSGDInV 168
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2071063243 188 CLGTIYGNIDIHASDKS-TVTIDKLQGSCVNISTEDG--------LLQAKYLYTDSSFVSSAAGDIALGNIHGNIVLE 256
Cdd:pfam13349 169 SNTTIAGSLKITATSGDiDLSLPDSASFGVDASSTSGdvtipykfDEEGTEENRIYGTNGNGKHKVDISTSSGDITVR 246
 
Name Accession Description Interval E-value
YvlB COG3595
Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function ...
94-286 2.76e-04

Uncharacterized conserved protein YvlB, contains DUF4097 and DUF4098 domains [Function unknown];


Pssm-ID: 442814 [Multi-domain]  Cd Length: 254  Bit Score: 42.16  E-value: 2.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071063243  94 VGSGTRGLDSLQVKYDAALQEMAILSDDIDPEASVEVNAPVKFDLNIESSGAGSVSVQNIECDSCKIDTEQGTSILQSVK 173
Cdd:COG3595     5 SAEIAAAVSVIAVVAGSIVVGLKTSRGSVDASSGGSVRRTVALGVDTGAALGGVDGVGGNGLAGASYLRVTSSGDVRVSG 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071063243 174 SQKLHVNTKGGDVVcLGTIYGNIDIHASDKStVTIDKLQGSCVNISTEDGLLQAKYLYTDSSFVSSAAGDIALGNIHGNI 253
Cdd:COG3595    85 VDDVSVKTSSGDVT-VEDLSGDLTVKTVSGD-IELSGLTGDEVELETVSGDITVKDGVGGDVEAKTVSGDITVDGASGSV 162
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 2071063243 254 VLESKMGNISVD---SSCGCLKASSDQGAIDVYISQ 286
Cdd:COG3595   163 EAKTVSGDIRLTlegAVAGRVKLKTVSGDVEVGLPE 198
DUF4097 pfam13349
Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a ...
128-256 3.75e-04

Putative adhesin; This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.


Pssm-ID: 433135 [Multi-domain]  Cd Length: 246  Bit Score: 41.54  E-value: 3.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2071063243 128 VEVNAPVKFDLNIESSGAGSVSVQNIECDSCKIDTEQG----------------TS---ILQSVKSQKLHVNTKGGDV-V 187
Cdd:pfam13349  89 ISVSDNLALKDVILSSNSGDITLKNVSAENLTIKSTSGdvsidgssakksklitTSgdiDLNNVSGKDLDLKSTSGDInV 168
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2071063243 188 CLGTIYGNIDIHASDKS-TVTIDKLQGSCVNISTEDG--------LLQAKYLYTDSSFVSSAAGDIALGNIHGNIVLE 256
Cdd:pfam13349 169 SNTTIAGSLKITATSGDiDLSLPDSASFGVDASSTSGdvtipykfDEEGTEENRIYGTNGNGKHKVDISTSSGDITVR 246
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH