NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1976284980|ref|NP_001380314|]
View 

capping protein-inhibiting regulator of actin dynamics isoform 2 [Homo sapiens]

Protein Classification

DUF4592 domain-containing protein( domain architecture ID 10633722)

DUF4592 domain-containing protein similar to Homo sapiens acrosomal protein KIAA1210, a novel X-chromosome-linked protein that localizes to the acrosome and associates with the ectoplasmic specialization in testes

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF4592 pfam15262
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ...
 3-115 9.11e-39

Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.


:

Pssm-ID: 464602 [Multi-domain]  Cd Length: 127  Bit Score: 140.63  E-value: 9.11e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980    3 KANSGEASLEEDLFLTSPMEIVTQQDIVLSdAENKSSDTPSSLSPLNLPGAGSEMEEKVAPVKPSRPKRHFSSAGTIESV 82
Cdd:pfam15262   16 RADDAGASSEDDGLPRSPPEISLLHEILLS-TESKSSDPPQHLSSLSLAGTGSEEEEQSTPVKSSRPKSPFSPSGTIEPI 94

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1976284980   83 NLDAIPLAIARLDNSAAKHKLAVKPKKQRVSKK 115
Cdd:pfam15262   95 NFDAPPQALACLDNSAAKHKLSVKPKNQRASRK 127
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 565-1002 4.07e-10

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.57  E-value: 4.07e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  565 GLEEKkhAEAPAGENPPRGPGDARAgsgkAKPRQESPSSASALaewasirsrilKNAESDPRSSERDQLRPGDESTPRGR 644
Cdd:PHA03247  2539 GLEEL--ASDDAGDPPPPLPPAAPP----AAPDRSVPPPRPAP-----------RPSEPAVTSRARRPDAPPQSARPRAP 2601

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  645 CDSRGNQRKTPPVNAKFSIMPAWQKFSDGGTETSKQSTEAESIRKRPMLGPSEETAPQ--PPPAGVRELGKGPEKSEMHR 722
Cdd:PHA03247  2602 VDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGrvSRPRRARRLGRAAQASSPPQ 2681

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  723 EP---------------ADTTEGCKFAKDLPSFLVPSLPYPPQKVVAHTEFTTSSDSETANGIAKPdPVMPGGEEKASpf 787
Cdd:PHA03247  2682 RPrrraarptvgsltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAG-PATPGGPARPA-- 2758

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  788 giklrrtnyslrfncdqqAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQ-APSTRRDSAEPS 866
Cdd:PHA03247  2759 ------------------RPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPpAAVLAPAAALPP 2820

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  867 SSRSVPvahPGPPPASSQTPAPEHDKAANKMPLAQKPALAP------KPTSQTPPASPLSKLSRPylvellSRRAGRPDP 940
Cdd:PHA03247  2821 AASPAG---PLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvrrRPPSRSPAAKPAAPARPP------VRRLARPAV 2891

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1976284980  941 EPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQQEKPSQTPEAG 1002
Cdd:PHA03247  2892 SRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAG 2953
PTZ00121 super family cl31754
MAEBL; Provisional
 161-468 1.44e-05

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  161 EERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPL-------EAERAPREEQ 233
Cdd:PTZ00121  1221 EDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELkkaeekkKADEAKKAEE 1300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  234 QRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEE-EEGRCAEELKRQEEEEAEGWE 312
Cdd:PTZ00121  1301 KKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEaEAAEEKAEAAEKKKEEAKKKA 1380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  313 ELEQQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAhlEDWRGQLSELLNDFEERLEDQERLKPEGQREHSEEPGI 392
Cdd:PTZ00121  1381 DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA--DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK 1458

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1976284980  393 CEEQNPEAERRREQQGRSGDFQGADRPGPEEKREEgdtEPLLKQEGPVEAAQPPVERKEAAALEQGRKVEELRWQE 468
Cdd:PTZ00121  1459 AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE---EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531
rne super family cl35953
ribonuclease E; Reviewed
 876-1159 3.70e-03

ribonuclease E; Reviewed


The actual alignment was detected with superfamily member PRK10811:

Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.56  E-value: 3.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  876 PGPPPASSQTPAPEHDKAAnkmplaqkpalAPKPTSQTPPASPlSKLSRpYLVELLSRRAGRPDPEPSEPSKEDQESSDR 955
Cdd:PRK10811   535 PDVPPAPTPAEPAAPVVAA-----------APKAAAATPPAQP-GLLSR-FFGALKALFSGGEETKPQEQPAPKAEAKPE 601

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  956 RPPSPPGPeeRKGQKRDEEEEATERKPASPPLPATQQEKPSQtpeaGRKEKPMLQS-RHSLDGSKLTEKVETAQPlwitl 1034
Cdd:PRK10811   602 RQQDRRKP--RQNNRRDRNERRDTRDNRTRREGRENREENRR----NRRQAQQQTAeTRESQQAEVTEKARTQDE----- 670

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980 1035 alQKQKGFREQQATREERKqaREAKQAEK-LSKENVSVSVQpgsssvsragslhkstalPEEKRPETAVSRLERReQLKK 1113
Cdd:PRK10811   671 --QQQAPRRERQRRRNDEK--RQAQQEAKaLNVEEQSVQET------------------EQEERVQQVQPRRKQR-QLNQ 727

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1976284980 1114 ANTLPTSVTVEISDSAPPAPLVKEVTkrfsTPDAAPVSTEPAWLAL 1159
Cdd:PRK10811   728 KVRIEQSVAEEAVAPVVEETVAAEPV----VQEVPAPRTELVKVPL 769
 
Name Accession Description Interval E-value
DUF4592 pfam15262
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ...
 3-115 9.11e-39

Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.


Pssm-ID: 464602 [Multi-domain]  Cd Length: 127  Bit Score: 140.63  E-value: 9.11e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980    3 KANSGEASLEEDLFLTSPMEIVTQQDIVLSdAENKSSDTPSSLSPLNLPGAGSEMEEKVAPVKPSRPKRHFSSAGTIESV 82
Cdd:pfam15262   16 RADDAGASSEDDGLPRSPPEISLLHEILLS-TESKSSDPPQHLSSLSLAGTGSEEEEQSTPVKSSRPKSPFSPSGTIEPI 94

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1976284980   83 NLDAIPLAIARLDNSAAKHKLAVKPKKQRVSKK 115
Cdd:pfam15262   95 NFDAPPQALACLDNSAAKHKLSVKPKNQRASRK 127
PHA03247 PHA03247
large tegument protein UL36; Provisional
 565-1002 4.07e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.57  E-value: 4.07e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  565 GLEEKkhAEAPAGENPPRGPGDARAgsgkAKPRQESPSSASALaewasirsrilKNAESDPRSSERDQLRPGDESTPRGR 644
Cdd:PHA03247  2539 GLEEL--ASDDAGDPPPPLPPAAPP----AAPDRSVPPPRPAP-----------RPSEPAVTSRARRPDAPPQSARPRAP 2601

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  645 CDSRGNQRKTPPVNAKFSIMPAWQKFSDGGTETSKQSTEAESIRKRPMLGPSEETAPQ--PPPAGVRELGKGPEKSEMHR 722
Cdd:PHA03247  2602 VDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGrvSRPRRARRLGRAAQASSPPQ 2681

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  723 EP---------------ADTTEGCKFAKDLPSFLVPSLPYPPQKVVAHTEFTTSSDSETANGIAKPdPVMPGGEEKASpf 787
Cdd:PHA03247  2682 RPrrraarptvgsltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAG-PATPGGPARPA-- 2758

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  788 giklrrtnyslrfncdqqAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQ-APSTRRDSAEPS 866
Cdd:PHA03247  2759 ------------------RPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPpAAVLAPAAALPP 2820

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  867 SSRSVPvahPGPPPASSQTPAPEHDKAANKMPLAQKPALAP------KPTSQTPPASPLSKLSRPylvellSRRAGRPDP 940
Cdd:PHA03247  2821 AASPAG---PLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvrrRPPSRSPAAKPAAPARPP------VRRLARPAV 2891

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1976284980  941 EPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQQEKPSQTPEAG 1002
Cdd:PHA03247  2892 SRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAG 2953
PTZ00121 PTZ00121
MAEBL; Provisional
 161-468 1.44e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  161 EERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPL-------EAERAPREEQ 233
Cdd:PTZ00121  1221 EDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELkkaeekkKADEAKKAEE 1300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  234 QRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEE-EEGRCAEELKRQEEEEAEGWE 312
Cdd:PTZ00121  1301 KKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEaEAAEEKAEAAEKKKEEAKKKA 1380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  313 ELEQQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAhlEDWRGQLSELLNDFEERLEDQERLKPEGQREHSEEPGI 392
Cdd:PTZ00121  1381 DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA--DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK 1458

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1976284980  393 CEEQNPEAERRREQQGRSGDFQGADRPGPEEKREEgdtEPLLKQEGPVEAAQPPVERKEAAALEQGRKVEELRWQE 468
Cdd:PTZ00121  1459 AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE---EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531
rne PRK10811
ribonuclease E; Reviewed
 876-1159 3.70e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.56  E-value: 3.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  876 PGPPPASSQTPAPEHDKAAnkmplaqkpalAPKPTSQTPPASPlSKLSRpYLVELLSRRAGRPDPEPSEPSKEDQESSDR 955
Cdd:PRK10811   535 PDVPPAPTPAEPAAPVVAA-----------APKAAAATPPAQP-GLLSR-FFGALKALFSGGEETKPQEQPAPKAEAKPE 601

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  956 RPPSPPGPeeRKGQKRDEEEEATERKPASPPLPATQQEKPSQtpeaGRKEKPMLQS-RHSLDGSKLTEKVETAQPlwitl 1034
Cdd:PRK10811   602 RQQDRRKP--RQNNRRDRNERRDTRDNRTRREGRENREENRR----NRRQAQQQTAeTRESQQAEVTEKARTQDE----- 670

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980 1035 alQKQKGFREQQATREERKqaREAKQAEK-LSKENVSVSVQpgsssvsragslhkstalPEEKRPETAVSRLERReQLKK 1113
Cdd:PRK10811   671 --QQQAPRRERQRRRNDEK--RQAQQEAKaLNVEEQSVQET------------------EQEERVQQVQPRRKQR-QLNQ 727

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1976284980 1114 ANTLPTSVTVEISDSAPPAPLVKEVTkrfsTPDAAPVSTEPAWLAL 1159
Cdd:PRK10811   728 KVRIEQSVAEEAVAPVVEETVAAEPV----VQEVPAPRTELVKVPL 769
 
Name Accession Description Interval E-value
DUF4592 pfam15262
Domain of unknown function (DUF4592); This protein family is a domain of unknown function, ...
 3-115 9.11e-39

Domain of unknown function (DUF4592); This protein family is a domain of unknown function, which lies to the N-terminus of the protein. This domain family is found in eukaryotes, and is typically between 114 and 130 amino acids in length. There are two completely conserved residues (L and A) that may be functionally important. In humans, the gene that encodes this protein lies in the position, chromosome 2 open reading frame 55.


Pssm-ID: 464602 [Multi-domain]  Cd Length: 127  Bit Score: 140.63  E-value: 9.11e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980    3 KANSGEASLEEDLFLTSPMEIVTQQDIVLSdAENKSSDTPSSLSPLNLPGAGSEMEEKVAPVKPSRPKRHFSSAGTIESV 82
Cdd:pfam15262   16 RADDAGASSEDDGLPRSPPEISLLHEILLS-TESKSSDPPQHLSSLSLAGTGSEEEEQSTPVKSSRPKSPFSPSGTIEPI 94

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1976284980   83 NLDAIPLAIARLDNSAAKHKLAVKPKKQRVSKK 115
Cdd:pfam15262   95 NFDAPPQALACLDNSAAKHKLSVKPKNQRASRK 127
PHA03247 PHA03247
large tegument protein UL36; Provisional
 565-1002 4.07e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.57  E-value: 4.07e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  565 GLEEKkhAEAPAGENPPRGPGDARAgsgkAKPRQESPSSASALaewasirsrilKNAESDPRSSERDQLRPGDESTPRGR 644
Cdd:PHA03247  2539 GLEEL--ASDDAGDPPPPLPPAAPP----AAPDRSVPPPRPAP-----------RPSEPAVTSRARRPDAPPQSARPRAP 2601

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  645 CDSRGNQRKTPPVNAKFSIMPAWQKFSDGGTETSKQSTEAESIRKRPMLGPSEETAPQ--PPPAGVRELGKGPEKSEMHR 722
Cdd:PHA03247  2602 VDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGrvSRPRRARRLGRAAQASSPPQ 2681

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  723 EP---------------ADTTEGCKFAKDLPSFLVPSLPYPPQKVVAHTEFTTSSDSETANGIAKPdPVMPGGEEKASpf 787
Cdd:PHA03247  2682 RPrrraarptvgsltslADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAG-PATPGGPARPA-- 2758

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  788 giklrrtnyslrfncdqqAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQ-APSTRRDSAEPS 866
Cdd:PHA03247  2759 ------------------RPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPpAAVLAPAAALPP 2820

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  867 SSRSVPvahPGPPPASSQTPAPEHDKAANKMPLAQKPALAP------KPTSQTPPASPLSKLSRPylvellSRRAGRPDP 940
Cdd:PHA03247  2821 AASPAG---PLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPggdvrrRPPSRSPAAKPAAPARPP------VRRLARPAV 2891

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1976284980  941 EPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQQEKPSQTPEAG 1002
Cdd:PHA03247  2892 SRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAG 2953
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 634-991 1.36e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 52.87  E-value: 1.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  634 RPGDESTPRGRCDSRGNQRKTPPVNAKFSIMPAWQKFSDGGTETSKQSTEAEsirkrPMLGPSEETAPQPPP--AGVREL 711
Cdd:PHA03307    66 EPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPP-----PPTPPPASPPPSPAPdlSEMLRP 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  712 GKGPEKSEMHREPADTTEGCKFAKDLPSflvPSLPYPPQKVVAHTEFTTSSDSETANGIAKPDPVMPGGEEKASPFGIK- 790
Cdd:PHA03307   141 VGSPGPPPAASPPAAGASPAAVASDAAS---SRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASa 217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  791 -------LRRTNYSLRFNCDQQAEQKKKkRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSA 863
Cdd:PHA03307   218 sspapapGRSAADDAGASSSDSSSSESS-GCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSP 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  864 EPSSSRS-VPVAHPGPPPASSQTPAPEHDKAAnkmPLAQKPALAPKPTSQTPPASPLSKLSRPylvellsrragRPDPEP 942
Cdd:PHA03307   297 SPSPSSPgSGPAPSSPRASSSSSSSRESSSSS---TSSSSESSRGAAVSPGPSPSRSPSPSRP-----------PPPADP 362

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1976284980  943 SEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQ 991
Cdd:PHA03307   363 SSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGR 411
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
820-1011 7.70e-06

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 50.26  E-value: 7.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  820 SADAGPPAAGSARGEKEMEGVALKhgpslpqerKQAPSTRRD--SAEPSSSRSVPVAHPGPPPASSQTPAPehdkAANKM 897
Cdd:PRK12323   413 AAAARAVAAAPARRSPAPEALAAA---------RQASARGPGgaPAPAPAPAAAPAAAARPAAAGPRPVAA----AAAAA 479

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  898 PLAQKPALAPKPTSQTPPasPLSKLSrpylvellsrragrpdPEPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEA 977
Cdd:PRK12323   480 PARAAPAAAPAPADDDPP--PWEELP----------------PEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETL 541

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1976284980  978 TERKPASPPLPATQQEKPSQTPEAGRKEKPMLQS 1011
Cdd:PRK12323   542 APAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
PHA03247 PHA03247
large tegument protein UL36; Provisional
 467-1010 8.62e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 50.32  E-value: 8.62e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  467 QEVDERQTMPRPYTFQVSSGGKQILFPKVNLSPVTPAKDTGLTAAPQEPKAPkaSPVQHALPSSLSVPHTAILVTGaqlc 546
Cdd:PHA03247  2566 RSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPL--PPDTHAPDPPPPSPSPAANEPD---- 2639

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  547 gpavnlsqikdtacksllgleEKKHAEAPAGENPPRGPGDARAGSGKAKPRQESPSSASALAEwaSIRSRILKNAESdPR 626
Cdd:PHA03247  2640 ---------------------PHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQ--RPRRRAARPTVG-SL 2695

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  627 SSERDQLRPGDESTPRGRCDSRGNQRKTPPVNAKFSIMPAWQKFSDGGTETSKQSTEAESIRKRPML--GPSEETAPQPP 704
Cdd:PHA03247  2696 TSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTtaGPPAPAPPAAP 2775

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  705 PAGVRELGKGPEKSEMhrepadttegckfAKDLPSFLVPSLPYPPQKVVAHTEFTTSSDSETANGIAKPDPVMPGGEEKA 784
Cdd:PHA03247  2776 AAGPPRRLTRPAVASL-------------SESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP 2842

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  785 SPFGIKLRRTNYSLRFNCDqqAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAE 864
Cdd:PHA03247  2843 PGPPPPSLPLGGSVAPGGD--VRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQ 2920

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  865 PSSSRSVPVAHPGPPPASSQTP-APEHDKAANKMPLAQKP-----ALAPKPTSQTPPASPLSKLSRPYLVELLSRRAGRP 938
Cdd:PHA03247  2921 PQPPPPPQPQPPPPPPPRPQPPlAPTTDPAGAGEPSGAVPqpwlgALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHS 3000

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  939 DPEPSE--PSKEDQESSDRRPPS------PPGPEE-------RKGQKRDEEEEATERKPASPPLPATQQEKPSqTPEAGR 1003
Cdd:PHA03247  3001 LSRVSSwaSSLALHEETDPPPVSlkqtlwPPDDTEdsdadslFDSDSERSDLEALDPLPPEPHDPFAHEPDPA-TPEAGA 3079


                   ....*..
gi 1976284980 1004 KEKPMLQ 1010
Cdd:PHA03247  3080 RESPSSQ 3086
PTZ00121 PTZ00121
MAEBL; Provisional
 161-468 1.44e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  161 EERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPL-------EAERAPREEQ 233
Cdd:PTZ00121  1221 EDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELkkaeekkKADEAKKAEE 1300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  234 QRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEE-EEGRCAEELKRQEEEEAEGWE 312
Cdd:PTZ00121  1301 KKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEaEAAEEKAEAAEKKKEEAKKKA 1380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  313 ELEQQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAhlEDWRGQLSELLNDFEERLEDQERLKPEGQREHSEEPGI 392
Cdd:PTZ00121  1381 DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKA--DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKK 1458

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1976284980  393 CEEQNPEAERRREQQGRSGDFQGADRPGPEEKREEgdtEPLLKQEGPVEAAQPPVERKEAAALEQGRKVEELRWQE 468
Cdd:PTZ00121  1459 AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE---EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE 1531
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 561-989 3.02e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 48.53  E-value: 3.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  561 KSLLGLEEK---KHAEAPAGEN----PPRGPGDARAGSGKAKPRQESPSSASALAEWASIRSRILKnaESDPRSSERDQL 633
Cdd:PTZ00449   494 KKLAPIEEEdsdKHDEPPEGPEasglPPKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGK--KPGPAKEHKPSK 571

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  634 RPGDESTPRGRCDSRGNQRKTPPVNAKFSIMPawqkfSDGGTETSKQSTEAESIRKRPMlGPSEETAPQPPPAgvrelgk 713
Cdd:PTZ00449   572 IPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSA-----QRPTRPKSPKLPELLDIPKSPK-RPESPKSPKRPPP------- 638

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  714 gPEKSEMHREPadttEGCKFAKDLPSFLVPSLPYPPQ----------KVVAHTEFTTSS---DSETANGIAKPDPVMPGG 780
Cdd:PTZ00449   639 -PQRPSSPERP----EGPKIIKSPKPPKSPKPPFDPKfkekfyddylDAAAKSKETKTTvvlDESFESILKETLPETPGT 713

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  781 EEKASPFGIKLRRTNYSLRFncdqqaEQKKKKRHSSTGDSADAGPPAAGSARGEkemEGVALKHGPSLPQERKQAPSTRR 860
Cdd:PTZ00449   714 PFTTPRPLPPKLPRDEEFPF------EPIGDPDAEQPDDIEFFTPPEEERTFFH---ETPADTPLPDILAEEFKEEDIHA 784

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  861 DSAEPSSsrsvPVAHPGPPPASSQTPAPEHDKAANKMPLAQKPALAPKPTSQTP------PASPLSKLSR---------- 924
Cdd:PTZ00449   785 ETGEPDE----AMKRPDSPSEHEDKPPGDHPSLPKKRHRLDGLALSTTDLESDAgriakdASGKIVKLKRsksfddlttv 860

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1976284980  925 ---PYLVELLSR-----RAGRPDPEPSEPSKEDQESS--DRRPPSPPGPEERKGQKRdeeeeaTERKPASPPLPA 989
Cdd:PTZ00449   861 eeaEEMGAEARKivvddDGTEADDEDTHPPEEKHKSEvrRRRPPKKPSKPKKPSKPK------KPKKPDSAFIPS 929
PTZ00249 PTZ00249
variable surface protein Vir28; Provisional
 807-991 3.12e-05

variable surface protein Vir28; Provisional


Pssm-ID: 140276 [Multi-domain]  Cd Length: 516  Bit Score: 48.10  E-value: 3.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  807 EQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPqerkqapstrrdsaepsSSRSVPVAHPGPPpasSQTP 886
Cdd:PTZ00249   221 EQKAVTAHAHRRISGEARPPKHISFSSPHAHGRPPVETRPPNP-----------------VSVSSPQAHGRHP---GETH 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  887 APEHDKAANKMPLAQKPALAPKPTSQTPPASPLSKLSRPYLVE------LLSRRAGRPDP--------EPSEPSKEDQES 952
Cdd:PTZ00249   281 TPPLVTVPSSKAHDRNPVQTPTPTSVSGYSSQAKGLEKQAGGEsertssVPSEQFPLPLPvllplgqsGPLESSESEETD 360

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1976284980  953 SDRRPPSPPGPE----------ERKGQKRD-----EEEEATERKPASPPLPATQ 991
Cdd:PTZ00249   361 EYAGPKGLPEPElelvelqeedQRHGLKHDvdtfrEDEEDTFLQEGDQPAGSMQ 414
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 807-1026 9.90e-05

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 46.61  E-value: 9.90e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  807 EQKKKKRHSSTGDSAD--AGPPAAGSARGEKemegvalkhgPSLPQERKQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQ 884
Cdd:PTZ00449   490 KKSKKKLAPIEEEDSDkhDEPPEGPEASGLP----------PKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGK 559

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  885 TPAPEHDKAANKMP-LAQKPALAPKPTSQTPPASPlSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESSDRRPPSPPGP 963
Cdd:PTZ00449   560 KPGPAKEHKPSKIPtLSKKPEFPKDPKHPKDPEEP-KKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPP 638

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1976284980  964 EERKgqkrdeeeeATERKPASPPLPATQQEKPSQTPEAGRKEKPMLQSRHSLDGSKLTEKVET 1026
Cdd:PTZ00449   639 PQRP---------SSPERPEGPKIIKSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTT 692
PTZ00121 PTZ00121
MAEBL; Provisional
 97-473 9.97e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 9.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980   97 SAAKHKLAVKPKKQRVSKKHRRLAQDPQHEQGGLESRPCLDQNGHPGEDKPTWHEEEPNPLDSE---EERRRQEDYWREL 173
Cdd:PTZ00121  1361 AAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKkkaEEKKKADEAKKKA 1440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  174 EAKCKRQ--KAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERRERE 251
Cdd:PTZ00121  1441 EEAKKADeaKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE 1520

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  252 ERERLEAEEERRRLQAQA--QAEERRRLEEdaRLEERRRQEEEEGRCAEELKRQEEEEAEGWEELeqqeaevqgppEALE 329
Cdd:PTZ00121  1521 AKKADEAKKAEEAKKADEakKAEEKKKADE--LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKA-----------EEAK 1587

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  330 ETGEGRrgaeeedlgeEEEEGQAHLEDWRGQLSELLNDFEERLEDQERLKPEGQREHSEEPGICEEQnpeaERRREQQGR 409
Cdd:PTZ00121  1588 KAEEAR----------IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAE----EKKKAEELK 1653

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1976284980  410 SGDFQGADRPGPEEKREEGD---TEPLLKQEGPVEAAQPPVERKEaaalEQGRKVEELRWQEVDERQ 473
Cdd:PTZ00121  1654 KAEEENKIKAAEEAKKAEEDkkkAEEAKKAEEDEKKAAEALKKEA----EEAKKAEELKKKEAEEKK 1716
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 814-1003 1.59e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.13  E-value: 1.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  814 HSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKA 893
Cdd:PRK07764   626 APAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP 705

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  894 ANKMPLAQKPALAPKPTSQTPPASPLSklsrpylvellsRRAGRPDPEPSEPSKEDQESSDRRPPSPPGPEERKGQkrde 973
Cdd:PRK07764   706 AATPPAGQADDPAAQPPQAAQGASAPS------------PAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAA---- 769

                          170       180       190
                   ....*....|....*....|....*....|
gi 1976284980  974 eeeaterkPASPPLPATQQEKPSQTPEAGR 1003
Cdd:PRK07764   770 --------PAAAPPPSPPSEEEEMAEDDAP 791
PTZ00121 PTZ00121
MAEBL; Provisional
 98-473 3.01e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 45.13  E-value: 3.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980   98 AAKHKLAVKPKKQRVSKKHRRLAQDpqheqgglesrpcldqnghpgEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKc 177
Cdd:PTZ00121  1333 AAKKKAEEAKKAAEAAKAEAEAAAD---------------------EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK- 1390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  178 krQKAEAAeKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPgwEDAERREREERERLE 257
Cdd:PTZ00121  1391 --KKADEA-KKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK--KKAEEAKKAEEAKKK 1465

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  258 AEEERRRLQAQAQAEERRRLEEdarleeRRRQEEEEGRCAEELKRQEEEEAEGWEELEQQE---------------AEVQ 322
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADE------AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEakkadeakkaeeakkADEA 1539

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  323 GPPEALEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQL----SELLNDFEE-RLEDQERLKPEGQREHSEEPGICEEQN 397
Cdd:PTZ00121  1540 KKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMalrkAEEAKKAEEaRIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1976284980  398 PEAERRREQQGRSGDFQGADRPGPEEKREegdTEPLLKQEGPVEAAQPPVERKEAaalEQGRKVEELRWQEVDERQ 473
Cdd:PTZ00121  1620 IKAEELKKAEEEKKKVEQLKKKEAEEKKK---AEELKKAEEENKIKAAEEAKKAE---EDKKKAEEAKKAEEDEKK 1689
PTZ00121 PTZ00121
MAEBL; Provisional
 144-477 4.44e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.75  E-value: 4.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  144 EDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGqeppl 223
Cdd:PTZ00121  1258 EEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKAD----- 1332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  224 EAERAPREEQQRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQ 303
Cdd:PTZ00121  1333 AAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKK 1412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  304 EEEEAEGWEELEQQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGqahlEDWRGQLSELLNDFEERLEDQERLKPEGQ 383
Cdd:PTZ00121  1413 AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA----EEAKKKAEEAKKADEAKKKAEEAKKADEA 1488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  384 REHSEEPgicEEQNPEAERRREQQGRSGDFQGADRPGPEE---KREEGDTEPLLKQEGPVEAAQPPVERKEAAALEQGRK 460
Cdd:PTZ00121  1489 KKKAEEA---KKKADEAKKAAEAKKKADEAKKAEEAKKADeakKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKK 1565

                          330
                   ....*....|....*..
gi 1976284980  461 VEELRWQEVDERQTMPR 477
Cdd:PTZ00121  1566 AEEAKKAEEDKNMALRK 1582
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
819-966 5.30e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.46  E-value: 5.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  819 DSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKAAnkmp 898
Cdd:PRK07003   395 AVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDERDAQP---- 470

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1976284980  899 lAQKPALAPKPTSQTPPASPLSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESsdrrPPSPPGPEER 966
Cdd:PRK07003   471 -PADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPA----AAAPPAPEAR 533
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 865-1006 5.40e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 44.09  E-value: 5.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  865 PSSSRSVPVAHPGPPPASSQTPAPEHDKAANKMPLAQKPALAPKPTSQTPPASPLSKLSRPYLVEL--LSRRAGR---PD 939
Cdd:PRK07994   361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARqqLQRAQGAtkaKK 440

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1976284980  940 PEPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQQE-KPSQTPEAGRKEK 1006
Cdd:PRK07994   441 SEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVaTPKALKKALEHEK 508
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 815-1000 5.77e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 5.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  815 SSTGDSADAGPPAAGSARGEKEMEGV-ALKHGPSLPQERKQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHdka 893
Cdd:PRK07764   619 AAPAAPAAPAPAGAAAAPAEASAAPApGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAG--- 695

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  894 ankmplAQKPALAPKPTSQTPPASPLSKLSRPylvellsrragrpdPEPSEPSKEDQESSDRRPPSPPGPEERKGQKRDE 973
Cdd:PRK07764   696 ------AAPAQPAPAPAATPPAGQADDPAAQP--------------PQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAP 755

                          170       180
                   ....*....|....*....|....*..
gi 1976284980  974 EEEATERKPASPPLPATQQEKPSQTPE 1000
Cdd:PRK07764   756 AQPPPPPAPAPAAAPAAAPPPSPPSEE 782
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 860-1000 8.64e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.55  E-value: 8.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  860 RDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKAANKMPlAQKPALAPKPTSQTPPASPLSKLSRPYLVELLSRRAGRPD 939
Cdd:PRK14951   365 KPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAP-AAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1976284980  940 PEPSEPSkedqessdrrPPSPPGPEERKGQKRDEEEEATeRKPASPPLPATQQEKPSQTPE 1000
Cdd:PRK14951   444 AVALAPA----------PPAQAAPETVAIPVRVAPEPAV-ASAAPAPAAAPAAARLTPTEE 493
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 846-1012 2.61e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.98  E-value: 2.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  846 PSLPQERKQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKAankmPLAQKPALAPK--------------PTS 911
Cdd:PTZ00449   612 PKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKP----PKSPKPPFDPKfkekfyddyldaaaKSK 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  912 QTPPASPLSKLSRPYLVELLSRRAGRP--DPEPSEPSKEDQESSDRRP---PSPPGPEERKGQKRDEEEEA-TERKPASP 985
Cdd:PTZ00449   688 ETKTTVVLDESFESILKETLPETPGTPftTPRPLPPKLPRDEEFPFEPigdPDAEQPDDIEFFTPPEEERTfFHETPADT 767

                          170       180       190
                   ....*....|....*....|....*....|
gi 1976284980  986 PLPATQQE---KPSQTPEAGRKEKPMLQSR 1012
Cdd:PTZ00449   768 PLPDILAEefkEEDIHAETGEPDEAMKRPD 797
PTZ00121 PTZ00121
MAEBL; Provisional
 99-498 2.91e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.05  E-value: 2.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980   99 AKHKLAVKPKKQRVSKKHRRLAQDPQHEQGGLESRPCLDQNGHPGEDKPTWHEeepnpLDSEEERRRQEDYWRELEAKCK 178
Cdd:PTZ00121  1449 AKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADE-----AKKAAEAKKKADEAKKAEEAKK 1523

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  179 RQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQepplEAERAPREEQQRSLEAPGWEDAERREREERERLEA 258
Cdd:PTZ00121  1524 ADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKK----KAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK 1599

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  259 EEERrrlQAQAQAEERRRLEEDARLEER-RRQEEEEGRCAEELKRQEEEEAEGWE-ELEQQEAEVQGPPEALEETGEGRR 336
Cdd:PTZ00121  1600 LYEE---EKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEElKKAEEENKIKAAEEAKKAEEDKKK 1676

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  337 GAEEEDLGeeeeegqahlEDWRGQLSELLNDFEE-RLEDQERLKPEGQREHSEEPGICEEQNP----EAERRREQQGRSG 411
Cdd:PTZ00121  1677 AEEAKKAE----------EDEKKAAEALKKEAEEaKKAEELKKKEAEEKKKAEELKKAEEENKikaeEAKKEAEEDKKKA 1746

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  412 DfqgadrpgpEEKREEGDTEPLLKQEGPVEAAQPPVERKEAAALEQGRKVEELRWQEVDERQTMPRPYTFQVSSGGKQIL 491
Cdd:PTZ00121  1747 E---------EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEG 1817


                   ....*..
gi 1976284980  492 FPKVNLS 498
Cdd:PTZ00121  1818 NLVINDS 1824
rne PRK10811
ribonuclease E; Reviewed
 876-1159 3.70e-03

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 41.56  E-value: 3.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  876 PGPPPASSQTPAPEHDKAAnkmplaqkpalAPKPTSQTPPASPlSKLSRpYLVELLSRRAGRPDPEPSEPSKEDQESSDR 955
Cdd:PRK10811   535 PDVPPAPTPAEPAAPVVAA-----------APKAAAATPPAQP-GLLSR-FFGALKALFSGGEETKPQEQPAPKAEAKPE 601

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  956 RPPSPPGPeeRKGQKRDEEEEATERKPASPPLPATQQEKPSQtpeaGRKEKPMLQS-RHSLDGSKLTEKVETAQPlwitl 1034
Cdd:PRK10811   602 RQQDRRKP--RQNNRRDRNERRDTRDNRTRREGRENREENRR----NRRQAQQQTAeTRESQQAEVTEKARTQDE----- 670

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980 1035 alQKQKGFREQQATREERKqaREAKQAEK-LSKENVSVSVQpgsssvsragslhkstalPEEKRPETAVSRLERReQLKK 1113
Cdd:PRK10811   671 --QQQAPRRERQRRRNDEK--RQAQQEAKaLNVEEQSVQET------------------EQEERVQQVQPRRKQR-QLNQ 727

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*.
gi 1976284980 1114 ANTLPTSVTVEISDSAPPAPLVKEVTkrfsTPDAAPVSTEPAWLAL 1159
Cdd:PRK10811   728 KVRIEQSVAEEAVAPVVEETVAAEPV----VQEVPAPRTELVKVPL 769
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 818-948 4.01e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.24  E-value: 4.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  818 GDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSSRSVPvAHPGPPPASSQTPAPEHDKAANKM 897
Cdd:PRK14951   369 AAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPP-APVAAPAAAAPAAAPAAAPAAVAL 447

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1976284980  898 PLAQKPALAPKPTSQTPPASPlsklsRPYLVELLSRRAGRPDPEPSEPSKE 948
Cdd:PRK14951   448 APAPPAQAAPETVAIPVRVAP-----EPAVASAAPAPAAAPAAARLTPTEE 493
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
802-956 4.28e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 41.30  E-value: 4.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  802 CDQQAEQKKKKR----------HSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSSRSV 871
Cdd:PRK14971   338 CDLNYRASKNKRllveltliqlAQLTQKGDDASGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSA 417

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  872 PVAHPGPPPASSQTPAPEHDKAANKMPLAQKPalAPKPTSQTPPASPLSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQE 951
Cdd:PRK14971   418 TQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRP--AQFKEEKKIPVSKVSSLGPSTLRPIQEKAEQATGNIKEAPTGTQKE 495


                   ....*
gi 1976284980  952 SSDRR 956
Cdd:PRK14971   496 IFTEE 500
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 762-1018 5.66e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.92  E-value: 5.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  762 SDSETANGIAKPDPVMPGGEEKASPFGI---KLRRTNYSLRFNCDQQAEQKKKKRHSSTGDSADAGPPAAGSArgekemE 838
Cdd:PHA03307    51 AAVTVVAGAAACDRFEPPTGPPPGPGTEapaNESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPP------A 124

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  839 GVALKHGPSLPQERKQAPST-----RRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKAANKMPLAQKPALAPkPTSQT 913
Cdd:PHA03307   125 SPPPSPAPDLSEMLRPVGSPgpppaASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTP-PAAAS 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  914 PPASPLSKLSRPYLVELLSRRAGRP---------DPEPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEATERKPAS 984
Cdd:PHA03307   204 PRPPRRSSPISASASSPAPAPGRSAaddagasssDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPG 283

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1976284980  985 PPLPATQQEKPSQTPEAGRKEKPMLQSRHSLDGS 1018
Cdd:PHA03307   284 PASSSSSPRERSPSPSPSSPGSGPAPSSPRASSS 317
dnaA PRK14086
chromosomal replication initiator protein DnaA;
812-1002 7.66e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 40.19  E-value: 7.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  812 KRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPStRRDSAEPsssrsvpvahpGPPPASSQTPAPEHD 891
Cdd:PRK14086   103 RRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYPA-YQQRPEP-----------GAWPRAADDYGWQQQ 170

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1976284980  892 KAANkmplaqkPALAPkPTSQTPPASPLSKLSRPYLVELLSRRAGRPDPEPSEPS--KEDQESSDRRPPSPPGPEERKGQ 969
Cdd:PRK14086   171 RLGF-------PPRAP-YASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRPDwdRPRRDRTDRPEPPPGAGHVHRGG 242

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1976284980  970 KRDEEEEATERKPASPPLPATQQEKPSQTPEAG 1002
Cdd:PRK14086   243 PGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPG 275
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH