|
Name |
Accession |
Description |
Interval |
E-value |
| BirA2 |
COG0340 |
Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]; Biotin-(acetyl-CoA ... |
295-542 |
1.44e-35 |
|
Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]; Biotin-(acetyl-CoA carboxylase) ligase is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 440109 [Multi-domain] Cd Length: 241 Bit Score: 133.38 E-value: 1.44e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 295 YFEQIHSkigqvvllvdvattTMDI-IESVNAGIPslESVVVIANRQISGRGRGGNEFLCPRGMamfNFSFSISKKSRI- 372
Cdd:COG0340 4 VFDEVDS--------------TNDEaKELAREGAP--EGTVVVAEEQTAGRGRRGRSWVSPPGK---GLYFSLLLRPDLp 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 373 AKHLPILQHIFCVALVEAARNLSGypeFPLHIKWPNDLYCERsHKVGGMLLQCSTRDDSFRVS-IGCGMNVSN------- 444
Cdd:COG0340 65 PARLPLLSLAAGLAVAEALRELTG---VDVGLKWPNDILLNG-KKLAGILIEASGEGDGIDWVvIGIGINVNQppfdpee 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 445 -DKPTMCLNDmlpkEAETRITKEQLIAETINKFTYYMKDYEDNGPETFKKKYHEYWLHSQQEVLLSDFNERV--TIRGID 521
Cdd:COG0340 141 lDQPATSLKE----ETGKEVDREELLAALLEELEELYDRFLEEGFAPILEEWRARLATLGRRVRVETGGETLegIAVGID 216
|
250 260
....*....|....*....|.
gi 1972245508 522 DDGYLQVRSKSNPDKIFSIGD 542
Cdd:COG0340 217 EDGALLLETADGEIRAVAAGE 237
|
|
| BPL |
cd16442 |
biotin protein ligase; Biotin protein ligase (EC 6.3.4.15) catalyzes the synthesis of an ... |
307-479 |
3.16e-35 |
|
biotin protein ligase; Biotin protein ligase (EC 6.3.4.15) catalyzes the synthesis of an activated form of biotin, biotinyl-5'-AMP, from substrates biotin and ATP followed by biotinylation of the biotin carboxyl carrier protein subunit of acetyl-CoA carboxylase. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine.
Pssm-ID: 319741 [Multi-domain] Cd Length: 173 Bit Score: 130.08 E-value: 3.16e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 307 VLLVDVATTTMDIIESVNAGIPsLESVVVIANRQISGRGRGGNEFLCPRG-MAMFNFSFSISKKSriaKHLPILQHIFCV 385
Cdd:cd16442 2 LIVLDEIDSTNDEAKELARSGA-PEGTVVVAEEQTAGRGRRGRKWESPKGkGLYFSLLLRPDVPP---AEAPLLTLLAAV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 386 ALVEAARNLSGypeFPLHIKWPNDLYCErSHKVGGMLLQCSTRDDS-FRVSIGCGMNVSNDKPTMCLND-----MLPKEA 459
Cdd:cd16442 78 AVAEALEKLGG---IPVQIKWPNDILVN-GKKLAGILTEASAEGEGvAAVVIGIGINVNNTPPPEPLPDtslatSLGKEV 153
|
170 180
....*....|....*....|
gi 1972245508 460 ETRITKEQLIAETINKFTYY 479
Cdd:cd16442 154 DRNELLEELLAALENRLELF 173
|
|
| birA_ligase |
TIGR00121 |
birA, biotin-[acetyl-CoA-carboxylase] ligase region; This model represents the ... |
318-539 |
4.21e-21 |
|
birA, biotin-[acetyl-CoA-carboxylase] ligase region; This model represents the biotin--acetyl-CoA-carboxylase ligase region of biotin--acetyl-CoA-carboxylase ligase. In Escherichia coli and some other species, this enzyme is part of a bifunction protein BirA that includes a small, N-terminal biotin operon repressor domain. Proteins identified by this model should not be called bifunctional unless they are also identified by birA_repr_reg (TIGR00122). The protein name suggests that this enzyme transfers biotin only to acetyl-CoA-carboxylase but it also transfers the biotin moiety to other proteins. The apparent orthologs among the eukaryotes are larger proteins that contain a single copy of this domain. [Protein fate, Protein modification and repair]
Pssm-ID: 272917 [Multi-domain] Cd Length: 237 Bit Score: 92.47 E-value: 4.21e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 318 DIIESVN------AGIPSLESVVVIANRQISGRGRGGNEFLCPRGMAMFNF--SFSISKKSriakhLPILQHIFCVALVE 389
Cdd:TIGR00121 6 DVIDSTNqyalelAKEGKLKGDLVVAEYQTAGRGRRGRKWLSPEGGLYFSLilRPDLPKSP-----APGLTLVAGIAIAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 390 AARNLSgypeFPLHIKWPNDLYCErSHKVGGMLLQCSTRDDSFR-VSIGCGMNVSNDKPTMCLNDM---LPKEAETRITK 465
Cdd:TIGR00121 81 VLKELG----DQVQVKWPNDILLK-DKKLGGILTELTGKENRADyVVIGIGINVQNRKPAESLREQaisLSEEAGIDLDR 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972245508 466 EQLIAETINKFTYYMKDYEDNGPETFKKKYHEYWLHSQQEV-LLSDFNERVTI-RGIDDDGYLQVRSKSNPDKIFS 539
Cdd:TIGR00121 156 GELIEGFLRNFEENLEWFEQEGIDEILSKWEKLSAHIGREVsLTTGNGEIEGIaRGIDKDGALLLEDGGGIKKIIS 231
|
|
| PRK11886 |
PRK11886 |
bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; |
318-529 |
3.01e-18 |
|
bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA;
Pssm-ID: 237010 [Multi-domain] Cd Length: 319 Bit Score: 85.61 E-value: 3.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 318 DIIESVNA----GIPSLESV-VVIANRQISGRGRGGNEFLCPRGMamfNFSFSISKKSRI-AKHLPILQHIFCVALVEAA 391
Cdd:PRK11886 84 PVIDSTNQylldRIAELKSGdLCLAEYQTAGRGRRGRQWFSPFGG---NLYLSLYWRLNQgPAQAMGLSLVVGIAIAEAL 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 392 RNLsGYPEfpLHIKWPNDLYCeRSHKVGGMLLQCSTR-DDSFRVSIGCGMNVS--------NDKPTMCLNdmlpkEAETR 462
Cdd:PRK11886 161 RRL-GAID--VGLKWPNDIYL-NDRKLAGILVELSGEtGDAAHVVIGIGINVAmpdfpeelIDQPWSDLQ-----EAGPT 231
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1972245508 463 ITKEQLIAETINKFTYYMKDYEDNGPETFKKKYHEYWLHSQQEVLLSDFNERV--TIRGIDDDGYLQVR 529
Cdd:PRK11886 232 IDRNQLAAELIKQLRAALELFEQEGLAPFLERWKKLDLFLGREVKLIIGDKEIsgIARGIDEQGALLLE 300
|
|
| BPL_LplA_LipB |
pfam03099 |
Biotin/lipoate A/B protein ligase family; This family includes biotin protein ligase, ... |
314-441 |
1.26e-15 |
|
Biotin/lipoate A/B protein ligase family; This family includes biotin protein ligase, lipoate-protein ligase A and B. Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Each organizm probably has only one BPL. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine. Lipoate-protein ligase A (LPLA) catalyzes the formation of an amide linkage between lipoic acid and a specific lysine residue in lipoate dependent enzymes. The unusual biosynthesis pathway of lipoic acid is mechanistically intertwined with attachment of the cofactor.
Pssm-ID: 427135 Cd Length: 132 Bit Score: 73.63 E-value: 1.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 314 TTTMDIIESVNagIPSLES-VVVIANRQISGRGRGGNEFLCPRGMAMFNFSFSISKKSRIAKHLPILQHIFCVALVEAAR 392
Cdd:pfam03099 6 KSTNTYLEELN--SSELESgGVVVVRRQTGGRGRGGNVWHSPKGCLTYSLLLSKEHPNVDPSVLEFYVLELVLAVLEALG 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1972245508 393 N-LSGYPEFPLHIKWPNDLYCErSHKVGGmLLQCSTRD-DSFRVSIGCGMN 441
Cdd:pfam03099 84 LyKPGISGIPCFVKWPNDLYVN-GRKLAG-ILQRSTRGgTLHHGVIGLGVN 132
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| BirA2 |
COG0340 |
Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]; Biotin-(acetyl-CoA ... |
295-542 |
1.44e-35 |
|
Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme transport and metabolism]; Biotin-(acetyl-CoA carboxylase) ligase is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 440109 [Multi-domain] Cd Length: 241 Bit Score: 133.38 E-value: 1.44e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 295 YFEQIHSkigqvvllvdvattTMDI-IESVNAGIPslESVVVIANRQISGRGRGGNEFLCPRGMamfNFSFSISKKSRI- 372
Cdd:COG0340 4 VFDEVDS--------------TNDEaKELAREGAP--EGTVVVAEEQTAGRGRRGRSWVSPPGK---GLYFSLLLRPDLp 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 373 AKHLPILQHIFCVALVEAARNLSGypeFPLHIKWPNDLYCERsHKVGGMLLQCSTRDDSFRVS-IGCGMNVSN------- 444
Cdd:COG0340 65 PARLPLLSLAAGLAVAEALRELTG---VDVGLKWPNDILLNG-KKLAGILIEASGEGDGIDWVvIGIGINVNQppfdpee 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 445 -DKPTMCLNDmlpkEAETRITKEQLIAETINKFTYYMKDYEDNGPETFKKKYHEYWLHSQQEVLLSDFNERV--TIRGID 521
Cdd:COG0340 141 lDQPATSLKE----ETGKEVDREELLAALLEELEELYDRFLEEGFAPILEEWRARLATLGRRVRVETGGETLegIAVGID 216
|
250 260
....*....|....*....|.
gi 1972245508 522 DDGYLQVRSKSNPDKIFSIGD 542
Cdd:COG0340 217 EDGALLLETADGEIRAVAAGE 237
|
|
| BPL |
cd16442 |
biotin protein ligase; Biotin protein ligase (EC 6.3.4.15) catalyzes the synthesis of an ... |
307-479 |
3.16e-35 |
|
biotin protein ligase; Biotin protein ligase (EC 6.3.4.15) catalyzes the synthesis of an activated form of biotin, biotinyl-5'-AMP, from substrates biotin and ATP followed by biotinylation of the biotin carboxyl carrier protein subunit of acetyl-CoA carboxylase. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine.
Pssm-ID: 319741 [Multi-domain] Cd Length: 173 Bit Score: 130.08 E-value: 3.16e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 307 VLLVDVATTTMDIIESVNAGIPsLESVVVIANRQISGRGRGGNEFLCPRG-MAMFNFSFSISKKSriaKHLPILQHIFCV 385
Cdd:cd16442 2 LIVLDEIDSTNDEAKELARSGA-PEGTVVVAEEQTAGRGRRGRKWESPKGkGLYFSLLLRPDVPP---AEAPLLTLLAAV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 386 ALVEAARNLSGypeFPLHIKWPNDLYCErSHKVGGMLLQCSTRDDS-FRVSIGCGMNVSNDKPTMCLND-----MLPKEA 459
Cdd:cd16442 78 AVAEALEKLGG---IPVQIKWPNDILVN-GKKLAGILTEASAEGEGvAAVVIGIGINVNNTPPPEPLPDtslatSLGKEV 153
|
170 180
....*....|....*....|
gi 1972245508 460 ETRITKEQLIAETINKFTYY 479
Cdd:cd16442 154 DRNELLEELLAALENRLELF 173
|
|
| birA_ligase |
TIGR00121 |
birA, biotin-[acetyl-CoA-carboxylase] ligase region; This model represents the ... |
318-539 |
4.21e-21 |
|
birA, biotin-[acetyl-CoA-carboxylase] ligase region; This model represents the biotin--acetyl-CoA-carboxylase ligase region of biotin--acetyl-CoA-carboxylase ligase. In Escherichia coli and some other species, this enzyme is part of a bifunction protein BirA that includes a small, N-terminal biotin operon repressor domain. Proteins identified by this model should not be called bifunctional unless they are also identified by birA_repr_reg (TIGR00122). The protein name suggests that this enzyme transfers biotin only to acetyl-CoA-carboxylase but it also transfers the biotin moiety to other proteins. The apparent orthologs among the eukaryotes are larger proteins that contain a single copy of this domain. [Protein fate, Protein modification and repair]
Pssm-ID: 272917 [Multi-domain] Cd Length: 237 Bit Score: 92.47 E-value: 4.21e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 318 DIIESVN------AGIPSLESVVVIANRQISGRGRGGNEFLCPRGMAMFNF--SFSISKKSriakhLPILQHIFCVALVE 389
Cdd:TIGR00121 6 DVIDSTNqyalelAKEGKLKGDLVVAEYQTAGRGRRGRKWLSPEGGLYFSLilRPDLPKSP-----APGLTLVAGIAIAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 390 AARNLSgypeFPLHIKWPNDLYCErSHKVGGMLLQCSTRDDSFR-VSIGCGMNVSNDKPTMCLNDM---LPKEAETRITK 465
Cdd:TIGR00121 81 VLKELG----DQVQVKWPNDILLK-DKKLGGILTELTGKENRADyVVIGIGINVQNRKPAESLREQaisLSEEAGIDLDR 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972245508 466 EQLIAETINKFTYYMKDYEDNGPETFKKKYHEYWLHSQQEV-LLSDFNERVTI-RGIDDDGYLQVRSKSNPDKIFS 539
Cdd:TIGR00121 156 GELIEGFLRNFEENLEWFEQEGIDEILSKWEKLSAHIGREVsLTTGNGEIEGIaRGIDKDGALLLEDGGGIKKIIS 231
|
|
| PRK11886 |
PRK11886 |
bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA; |
318-529 |
3.01e-18 |
|
bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA;
Pssm-ID: 237010 [Multi-domain] Cd Length: 319 Bit Score: 85.61 E-value: 3.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 318 DIIESVNA----GIPSLESV-VVIANRQISGRGRGGNEFLCPRGMamfNFSFSISKKSRI-AKHLPILQHIFCVALVEAA 391
Cdd:PRK11886 84 PVIDSTNQylldRIAELKSGdLCLAEYQTAGRGRRGRQWFSPFGG---NLYLSLYWRLNQgPAQAMGLSLVVGIAIAEAL 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 392 RNLsGYPEfpLHIKWPNDLYCeRSHKVGGMLLQCSTR-DDSFRVSIGCGMNVS--------NDKPTMCLNdmlpkEAETR 462
Cdd:PRK11886 161 RRL-GAID--VGLKWPNDIYL-NDRKLAGILVELSGEtGDAAHVVIGIGINVAmpdfpeelIDQPWSDLQ-----EAGPT 231
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1972245508 463 ITKEQLIAETINKFTYYMKDYEDNGPETFKKKYHEYWLHSQQEVLLSDFNERV--TIRGIDDDGYLQVR 529
Cdd:PRK11886 232 IDRNQLAAELIKQLRAALELFEQEGLAPFLERWKKLDLFLGREVKLIIGDKEIsgIARGIDEQGALLLE 300
|
|
| BPL_LplA_LipB |
pfam03099 |
Biotin/lipoate A/B protein ligase family; This family includes biotin protein ligase, ... |
314-441 |
1.26e-15 |
|
Biotin/lipoate A/B protein ligase family; This family includes biotin protein ligase, lipoate-protein ligase A and B. Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Each organizm probably has only one BPL. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine. Lipoate-protein ligase A (LPLA) catalyzes the formation of an amide linkage between lipoic acid and a specific lysine residue in lipoate dependent enzymes. The unusual biosynthesis pathway of lipoic acid is mechanistically intertwined with attachment of the cofactor.
Pssm-ID: 427135 Cd Length: 132 Bit Score: 73.63 E-value: 1.26e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 314 TTTMDIIESVNagIPSLES-VVVIANRQISGRGRGGNEFLCPRGMAMFNFSFSISKKSRIAKHLPILQHIFCVALVEAAR 392
Cdd:pfam03099 6 KSTNTYLEELN--SSELESgGVVVVRRQTGGRGRGGNVWHSPKGCLTYSLLLSKEHPNVDPSVLEFYVLELVLAVLEALG 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1972245508 393 N-LSGYPEFPLHIKWPNDLYCErSHKVGGmLLQCSTRD-DSFRVSIGCGMN 441
Cdd:pfam03099 84 LyKPGISGIPCFVKWPNDLYVN-GRKLAG-ILQRSTRGgTLHHGVIGLGVN 132
|
|
| PRK08330 |
PRK08330 |
biotin--protein ligase; Provisional |
303-447 |
3.46e-10 |
|
biotin--protein ligase; Provisional
Pssm-ID: 169384 [Multi-domain] Cd Length: 236 Bit Score: 60.53 E-value: 3.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 303 IGQVVLLVDVATTTMDIIESVNAGIPslESVVVIANRQISGRGRGGNEFLCPRG---MAMfnfsfsISKKSRIAKHLPIL 379
Cdd:PRK08330 1 IGRNIIYFDEVDSTNEYAKRIAPDEE--EGTVIVADRQTAGHGRKGRAWASPEGglwMSV------ILKPKVSPEHLPKL 72
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1972245508 380 QHIFCVALVEAARNLSgypeFPLHIKWPNDLYCErSHKVGGMLLQCStrddSFRVSIGCGMNVSNDKP 447
Cdd:PRK08330 73 VFLGALAVVDTLREFG----IEGKIKWPNDVLVN-YKKIAGVLVEGK----GDFVVLGIGLNVNNEIP 131
|
|
| PTZ00276 |
PTZ00276 |
biotin/lipoate protein ligase; Provisional |
309-443 |
9.11e-10 |
|
biotin/lipoate protein ligase; Provisional
Pssm-ID: 140302 [Multi-domain] Cd Length: 245 Bit Score: 59.49 E-value: 9.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 309 LVDVATTTMDIIESVNAGIPSlESVVVIANRQISGRGRGGNEFLCPRGmAMFnFSFSISKKSRIAKHLPILQHIfcVALV 388
Cdd:PTZ00276 11 FVGEVTSTMDVARTMLAAAGG-KPFAVLAESQTAGRGTGGRTWTSPKG-NMY-FTLCIPQKGVPPELVPVLPLI--TGLA 85
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1972245508 389 EAARNLSGYPEFPLHIKWPND-LYCERshKVGGMLLQCstrdDSFRVSIGCGMNVS 443
Cdd:PTZ00276 86 CRAAIMEVLHGAAVHTKWPNDiIYAGK--KIGGSLIES----EGEYLIIGIGMNIE 135
|
|
| BirA |
COG1654 |
Biotin operon repressor [Transcription]; |
294-524 |
2.67e-09 |
|
Biotin operon repressor [Transcription];
Pssm-ID: 441260 [Multi-domain] Cd Length: 324 Bit Score: 58.84 E-value: 2.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 294 LYFEQIH-----SKIGQVVLLVDVATTTMDIiESVNAGIPSLESVVVIANRQISGRGRGGNEflcPRGMAMFNFSFSISK 368
Cdd:COG1654 66 LDPEEIRaglstKRLGREILYVISSTSTNLL-ALELAAQGGDAGTVVAAEQQRGGRGRRRRS---WSSPGGGGLLYSLLL 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 369 KSRIAkhLPILQHIFCVALVEAARNLSGYPEFPLHIKWPNDLYCERsHKVGGMLLQCSTRDDSFRVSIGCGMNVSNDKPT 448
Cdd:COG1654 142 RPPIA--PALLSLLLLAAAVAVAAALAEGGGLVKWKKWPNDLLKKG-KKILGILEEEGGDADGVVIVVGGGGNNNNSNPE 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 449 M------CLNDMLPKEAETRITKEQLIAETINKFTYYMKDYEDNGPETFKKKYHEYWLHSQQEVLLSDFNERVTIRGIDD 522
Cdd:COG1654 219 EepqelaELATSLLLILRLRLLRLLLLLLLLLLELLELLGFLEFFFLWERLDWELLRVLKLVVVVVEIGGGGGGGGALGG 298
|
..
gi 1972245508 523 DG 524
Cdd:COG1654 299 GL 300
|
|
| PRK13325 |
PRK13325 |
bifunctional biotin--[acetyl-CoA-carboxylase] ligase/type III pantothenate kinase; |
305-539 |
8.03e-06 |
|
bifunctional biotin--[acetyl-CoA-carboxylase] ligase/type III pantothenate kinase;
Pssm-ID: 183976 [Multi-domain] Cd Length: 592 Bit Score: 48.55 E-value: 8.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 305 QVVLLVDVATTTMDIIESVNAGIPSLESVVVIANRQISGRGRGGNEFLCPRGMA-MFNFSFSISKKSRIAKHLPILQHIF 383
Cdd:PRK13325 83 QTALKHECASSNDEILELARIAPDKAHKTICVTHLQSKGRGRQGRKWSHRLGEClMFSFGWVFDRPQYELGSLSPVAAVA 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 384 CvalveaaRNLSGYPEFPLHIKWPNDLYCERShKVGGMLLQCSTRDDSFRVSIGCGMN------VSNDKPTMCLNDMLPK 457
Cdd:PRK13325 163 C-------RRALSRLGLKTQIKWPNDLVVGRD-KLGGILIETVRTGGKTVAVVGIGINfvlpkeVENAASVQSLFQTASR 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 458 E--AETRITKEQLIAEtinkFTYYMKDYEDNGPETFKKKYHEYWLHSQQEVLLSDFNERV---TIRGIDDDGYLQVRSKS 532
Cdd:PRK13325 235 RgnADAAVLLETLLAE----LDAVLLQYARDGFAPFVAEYQAANRDHGKAVLLLRDGETVfegTVKGVDGQGVLHLETAE 310
|
....*..
gi 1972245508 533 NPDKIFS 539
Cdd:PRK13325 311 GKQTVVS 317
|
|
| PRK06955 |
PRK06955 |
biotin--[acetyl-CoA-carboxylase] ligase; |
334-526 |
4.38e-05 |
|
biotin--[acetyl-CoA-carboxylase] ligase;
Pssm-ID: 235896 [Multi-domain] Cd Length: 300 Bit Score: 45.54 E-value: 4.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 334 VVIANRQISGRGRGGNEFLCPRGMAMfnfSFSIS-KKSRIAKHLPILQHIFCVALVEAARNLSGYPEFPLHIKWPNDLYC 412
Cdd:PRK06955 67 VRVAYEQTAGRGRQGRPWFAQPGNAL---LFSVAcVLPRPVAALAGLSLAVGVALAEALAALPAALGQRIALKWPNDLLI 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 413 ERShKVGGMLLQCS-TRDDSFRVSIGCGMNVSNDKPTMCLNDM-----------LPKEAETRITKE----QLIAETINKF 476
Cdd:PRK06955 144 AGR-KLAGILIETVwATPDATAVVIGIGLNVRRADAVAAEVDAlrareaalargLPPVALAAACAGanltDTLAAALNAL 222
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1972245508 477 TYYMKDYEDNGPETFKKKYHEYWLHSQQEV-LLSDFNERV--TIRGIDDDGYL 526
Cdd:PRK06955 223 APALQAFGADGLAPFAARWHALHAYAGREVvLLEDGAELArgVAHGIDETGQL 275
|
|
| PRK08477 |
PRK08477 |
biotin--[acetyl-CoA-carboxylase] ligase; |
333-442 |
1.43e-03 |
|
biotin--[acetyl-CoA-carboxylase] ligase;
Pssm-ID: 236273 [Multi-domain] Cd Length: 211 Bit Score: 40.32 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972245508 333 VVVIANRQISGRGRGGNEFLCPRGmAMFnFSFSIsKKSRIAKHLPiLQHI---FCVALVEAARNLSgypeFPLHIKWPND 409
Cdd:PRK08477 29 FAIVAKEQTAGIGSRGNSWEGKKG-NLF-FSFAL-KESDLPKDLP-LQSSsiyFGFLLKEVLKELG----SKVWLKWPND 100
|
90 100 110
....*....|....*....|....*....|...
gi 1972245508 410 LYCErSHKVGGMLlqcSTRDDSFRVsigCGMNV 442
Cdd:PRK08477 101 LYLD-DKKIGGVI---TNKIKNFIV---CGIGL 126
|
|
| |
