|
Name |
Accession |
Description |
Interval |
E-value |
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
24-356 |
0e+00 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 516.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 24 NAAIEDNAMEQDENFTVIDKLESSGISSGDISKLKEAGYYTYESLAFTTRRELRNVKGISDQKAEKIMKEAMKFVQMGFT 103
Cdd:PTZ00035 6 NEQQEEEEEEEAEGFQEIEKLQSAGINAADIKKLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAASKLVPMGFI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 104 TGAEVHVKRSQLVQIRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFR 183
Cdd:PTZ00035 86 SATEYLEARKNIIRITTGSTQLDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDTEGTFR 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 184 PERIIAIAQRYNMDSAHVLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGDLAERQMKLSA 263
Cdd:PTZ00035 166 PERIVQIAERFGLDPEDVLDNIAYARAYNHEHQMQLLSQAAAKMAEERFALLIVDSATALFRVDYSGRGELAERQQHLGK 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 264 FLKCLAKLADEYGVAVIITNQVVAQVDgGASMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAEAT 343
Cdd:PTZ00035 246 FLRALQKLADEFNVAVVITNQVMADVD-GASMFVADPKKPIGGHIIAHASTTRLSLRKGRGEQRICKIYDSPNLPESEAV 324
|
330
....*....|...
gi 1972267173 344 YSITNHGIEDARE 356
Cdd:PTZ00035 325 FAISEGGIIDAKD 337
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
41-356 |
4.48e-178 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 496.55 E-value: 4.48e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 41 IDKLESSGISSGDISKLKEAGYYTYESLAFTTRRELRNVKGISDQKAEKIMKEAMKFVQMGFTTGAEVHVKRSQLVQIRT 120
Cdd:TIGR02239 1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 121 GSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFRPERIIAIAQRYNMDSAH 200
Cdd:TIGR02239 81 GSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLNPED 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 201 VLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGDLAERQMKLSAFLKCLAKLADEYGVAVI 280
Cdd:TIGR02239 161 VLDNVAYARAYNTDHQLQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELSARQMHLARFLRSLQRLADEFGVAVV 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972267173 281 ITNQVVAQVDGGASMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAEATYSITNHGIEDARE 356
Cdd:TIGR02239 241 ITNQVVAQVDGAGSMFAGDPKKPIGGNIMAHASTTRLSLRKGRGEQRICKIYDSPCLPESEAMFAIYEDGIGDPKE 316
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
100-354 |
1.80e-175 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 487.19 E-value: 1.80e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 100 MGFTTGAEVHVKRSQLVQIRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTN 179
Cdd:pfam08423 1 MGFTTATELHQRRSELIQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 180 ATFRPERIIAIAQRYNMDSAHVLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGDLAERQM 259
Cdd:pfam08423 81 GTFRPERLVAIAERYGLDPEDVLDNVAYARAYNSEHQMQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELAERQQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 260 KLSAFLKCLAKLADEYGVAVIITNQVVAQVDGGASMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPE 339
Cdd:pfam08423 161 HLAKFLRTLQRLADEFGVAVVITNQVVAQVDGAAGMFSGDPKKPIGGHIMAHASTTRLSLRKGRGEQRICKIYDSPCLPE 240
|
250
....*....|....*
gi 1972267173 340 AEATYSITNHGIEDA 354
Cdd:pfam08423 241 SEAVFAIGSGGIIDP 255
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
118-353 |
6.74e-170 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 472.57 E-value: 6.74e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFRPERIIAIAQRYNMD 197
Cdd:cd19513 1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 198 SAHVLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGDLAERQMKLSAFLKCLAKLADEYGV 277
Cdd:cd19513 81 GEDVLDNVAYARAYNTDHQMQLLIQASAMMAESRYALLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972267173 278 AVIITNQVVAQVDGGAsMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAEATYSITNHGIED 353
Cdd:cd19513 161 AVVITNQVVAQVDGAA-MFAGDPKKPIGGNIMAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITEDGIGD 235
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
14-356 |
9.90e-170 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 476.15 E-value: 9.90e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 14 EQRAADQALLNAAIEDNAMEQDENFTvIDKLESSGISSGDISKLKEAGYYTYESLAFTTRRELRNVKGISDQKAEKIMKE 93
Cdd:PLN03186 2 AQAVAAAAAQAMQEEEEEEAAHGPFP-IEQLQASGIAALDIKKLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 94 AMKFVQMGFTTGAEVHVKRSQLVQIRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKC 173
Cdd:PLN03186 81 ASKLVPLGFTTASQLHAQRQEIIQITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTLCVTCQLPLDQGGGEGKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 174 MYIDTNATFRPERIIAIAQRYNMDSAHVLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGD 253
Cdd:PLN03186 161 MYIDTEGTFRPQRLIQIAERFGLNGADVLENVAYARAYNTDHQSELLLEAASMMAETRFALMIVDSATALYRTEFSGRGE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 254 LAERQMKLSAFLKCLAKLADEYGVAVIITNQVVAQVDgGASMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQ 333
Cdd:PLN03186 241 LSARQMHLGKFLRSLQRLADEFGVAVVITNQVVAQVD-GSAFFAGPQLKPIGGNIMAHASTTRLALRKGRGENRICKVIS 319
|
330 340
....*....|....*....|...
gi 1972267173 334 SPNLPEAEATYSITNHGIEDARE 356
Cdd:PLN03186 320 SPCLPEAEARFSISSEGVTDVKD 342
|
|
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
41-354 |
1.88e-135 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 388.37 E-value: 1.88e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 41 IDKLESSGISSGDISKLKEAGYYTYESLAFTTRRELRNVKGISDQKAEKIMKEAMKFVQMGFTTGAEVHVKRSQLVQIRT 120
Cdd:TIGR02238 1 IDKLQAHGINAADIKKLKSAGICTVNGVIMTTRRALCKIKGLSEAKVDKIKEAASKIINPGFITAFEISQKRKKVLKITT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 121 GSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFRPERIIAIAQRYNMDSAH 200
Cdd:TIGR02238 81 GSQALDGILGGGIESMSITEVFGEFRCGKTQLSHTLCVTAQLPREMGGGNGKVAYIDTEGTFRPDRIRAIAERFGVDPDA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 201 VLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGDLAERQMKLSAFLKCLAKLADEYGVAVI 280
Cdd:TIGR02238 161 VLDNILYARAYTSEHQMELLDYLAAKFSEEPFRLLIVDSIMALFRVDFSGRGELSERQQKLAQMLSRLNKISEEFNVAVF 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1972267173 281 ITNQVvaQVDGGASM-FQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAEATYSITNHGIEDA 354
Cdd:TIGR02238 241 VTNQV--QADPGATMtFIADPKKPIGGHVLAHASTTRILLRKGRGEERVAKLYDSPDMPEAEASFQITEGGIADA 313
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
16-356 |
2.00e-134 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 386.83 E-value: 2.00e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 16 RAADQALLNAAIEDNAMEQDENFTVIDKLESSGISSGDISKLKEAGYYTYESLAFTTRRELRNVKGISDQKAEKIMKEAM 95
Cdd:PLN03187 6 QADEGAQLQLVEAEEVDEEEDLFESIDKLISQGINAGDVKKLQDAGIYTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 96 KFVQMGFTTGAEVHVKRSQLVQIRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMY 175
Cdd:PLN03187 86 KLLNQGFITGSDALLKRKSVVRITTGSQALDELLGGGIETRCITEAFGEFRSGKTQLAHTLCVTTQLPTEMGGGNGKVAY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 176 IDTNATFRPERIIAIAQRYNMDSAHVLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGDLA 255
Cdd:PLN03187 166 IDTEGTFRPDRIVPIAERFGMDADAVLDNIIYARAYTYEHQYNLLLGLAAKMAEEPFRLLIVDSVIALFRVDFTGRGELA 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 256 ERQMKLSAFLKCLAKLADEYGVAVIITNQVVAqvDGGASMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSP 335
Cdd:PLN03187 246 ERQQKLAQMLSRLTKIAEEFNVAVYMTNQVIA--DPGGGMFISDPKKPAGGHVLAHAATIRLMLRKGKGEQRVCKVFDAP 323
|
330 340
....*....|....*....|.
gi 1972267173 336 NLPEAEATYSITNHGIEDARE 356
Cdd:PLN03187 324 NLPEAEAEFQITSGGIMDAKD 344
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
56-354 |
1.91e-132 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 380.76 E-value: 1.91e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 56 KLKEAGYYTYESLAFTTRRELRNVKGISDQKAEKIMKEAMKFVQM-GFTTGAEVHVKRSQLVQIRTGSASLDRLLGGGIE 134
Cdd:PRK04301 21 KLREAGYDTVEAIAVASPKELSEAAGIGESTAAKIIEAAREAADIgGFETALEVLERRKNVGKITTGSKELDELLGGGIE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 135 TGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFRPERIIAIAQRYNMDSAHVLENIAVARAYNSE 214
Cdd:PRK04301 101 TQSITEFYGEFGSGKTQICHQLAVNVQLPEEKGGLEGKAVYIDTEGTFRPERIEQMAEALGLDPDEVLDNIHVARAYNSD 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 215 HLMALIIRAGAMMSESR-YAVVIVDCATAHFRNEYTGRGDLAERQMKLSAFLKCLAKLADEYGVAVIITNQVVAQVDgga 293
Cdd:PRK04301 181 HQMLLAEKAEELIKEGEnIKLVIVDSLTAHFRAEYVGRGNLAERQQKLNKHLHDLLRLADLYNAAVVVTNQVMARPD--- 257
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1972267173 294 sMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAEATYSITNHGIEDA 354
Cdd:PRK04301 258 -AFFGDPTQPIGGHILGHTATFRIYLRKSKGNKRIARLVDSPHLPEGEAVFRITEEGIRDA 317
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
118-352 |
6.74e-130 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 371.09 E-value: 6.74e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFRPERIIAIAQRYNMD 197
Cdd:cd01123 1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAIYIDTEGTFRPERLRAIAQRFGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 198 SAHVLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGDLAERQMKLSAFLKCLAKLADEYGV 277
Cdd:cd01123 81 PDDVLDNVAYARAFNSDHQTQLLDQAAAMMVESRFKLLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1972267173 278 AVIITNQVVAQVDGGAsMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAEATYSITNHGIE 352
Cdd:cd01123 161 AVVVTNQVVAQVDGAM-MFAADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITADGVG 234
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
118-353 |
1.66e-127 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 365.14 E-value: 1.66e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFRPERIIAIAQRYNMD 197
Cdd:cd19514 1 ISTGSTELDKLLGGGIESMSITEVFGEFRTGKTQLSHTLCVTAQLPGSMGGGGGKVAYIDTEGTFRPDRIRPIAERFGVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 198 SAHVLENIAVARAYNSEHLMALIIRAGAMMSES-RYAVVIVDCATAHFRNEYTGRGDLAERQMKLSAFLKCLAKLADEYG 276
Cdd:cd19514 81 HDAVLDNILYARAYTSEHQMELLDYVAAKFHEEaVFRLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYN 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1972267173 277 VAVIITNQVVAQVdGGASMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAEATYSITNHGIED 353
Cdd:cd19514 161 VAVFITNQVTADP-GAAMTFQADPKKPIGGHILAHASTTRISLRKGRGEERIAKIYDSPDLPENEATFAITAGGIAD 236
|
|
| recomb_radA |
TIGR02236 |
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
56-353 |
7.37e-120 |
|
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 348.66 E-value: 7.37e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 56 KLKEAGYYTYESLAFTTRRELRNVKGISDQKAEKIMKEAMKFVQMG-FTTGAEVHVKRSQLVQIRTGSASLDRLLGGGIE 134
Cdd:TIGR02236 14 KLREAGYDTFEAIAVASPKELSEIAGISEGTAAKIIQAARKAADLGgFETADDVLERRKTIGKITTGSKELDELLGGGIE 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 135 TGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFRPERIIAIAQRYNMDSAHVLENIAVARAYNSE 214
Cdd:TIGR02236 94 TQAITEVFGEFGSGKTQICHQLAVNVQLPEEKGGLGGKAVYIDTENTFRPERIMQMAEARGLDPDEVLKNIYVARAYNSN 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 215 HLMALIIRAGAMMSESRYAV--VIVDCATAHFRNEYTGRGDLAERQMKLSAFLKCLAKLADEYGVAVIITNQVVAQVDgg 292
Cdd:TIGR02236 174 HQMLLVEKAEDLIKELNNPVklLIVDSLTSHFRAEYVGRGALAERQQKLNKHLHDLLRLADLYNAAVVVTNQVMARPD-- 251
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1972267173 293 asMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAEATYSITNHGIED 353
Cdd:TIGR02236 252 --AFFGDPTRPIGGHILGHAATFRVYLRKGKGDKRIARLVDSPHLPEGEAVFRITEKGIED 310
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
118-353 |
9.75e-111 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 322.39 E-value: 9.75e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFRPERIIAIAQRYNMD 197
Cdd:cd19515 1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPPEEGGLNGKAVYIDTENTFRPERIMQMAKALGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 198 SAHVLENIAVARAYNSEHLMALIIRAGAMMSESR-YAVVIVDCATAHFRNEYTGRGDLAERQMKLSAFLKCLAKLADEYG 276
Cdd:cd19515 81 PDEVLDNIYVARAYNSNHQMLLVEKAEDLIKEGNnIKLLIVDSLTSHFRAEYVGRGTLAERQQKLNKHLHDLHRLADLYN 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1972267173 277 VAVIITNQVVAQVDggasMFQADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAEATYSITNHGIED 353
Cdd:cd19515 161 IAVLVTNQVMAKPD----AFFGDPTQAIGGHILGHAATFRVYLRKGKGGKRIARLVDSPHLPEGEAVFRITEKGIED 233
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
136-321 |
5.04e-45 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 152.51 E-value: 5.04e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 136 GSITEVYGEYRTGKTQLCHSLAVLCQLpidmggGEGKCMYIDTNATFRPERIIAIAQRYNMDSAH---VLENIAVARAYN 212
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALL------LGGGVVWIDTEGAFPPSRLVQILEASPSSELElaeALSRLLYFRPPD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 213 S-EHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGD----LAERQMKLSAFLKCLAKLADEYGVAVIITNQVVA 287
Cdd:cd01393 75 TlAHLLALDSLPESLFPPPNTSLVVVDSVSALFRKAFPRGGDgdssSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTT 154
|
170 180 190
....*....|....*....|....*....|....
gi 1972267173 288 QVDGGasmFQADAKKPIGGHIIAHMSTTRLYLRK 321
Cdd:cd01393 155 KIRGG---SGASLVPPALGNTWEHSVSTRLLLYR 185
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
118-353 |
7.24e-45 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 153.48 E-value: 7.24e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLpidmggGEGKCMYIDTNAtFRPERIIAIAqryNMD 197
Cdd:PRK09361 5 LPTGCKMLDELLGGGFERGTITQIYGPPGSGKTNICLQLAVEAAK------NGKKVIYIDTEG-LSPERFKQIA---GED 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 198 SAHVLENIAVARAYNSEHlMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGDLAERQMKLSAFLKCLAKLADEYGV 277
Cdd:PRK09361 75 FEELLSNIIIFEPSSFEE-QSEAIRKAEKLAKENVGLIVLDSATSLYRLELEDEEDNSKLNRELGRQLTHLLKLARKHDL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1972267173 278 AVIITNQVVAQVDGGASmfqadakKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAE-ATYSITNHGIED 353
Cdd:PRK09361 154 AVVITNQVYSDIDSDGL-------RPLGGHTLEHWSKTILRLEKFRNGKRRATLEKHRSRPEGEsAEFRITDRGIEI 223
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
125-338 |
9.35e-42 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 146.28 E-value: 9.35e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 125 LDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFRPERIIAIAQRY-----NMDSA 199
Cdd:cd19491 1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQLALTVQLPRELGGLGGGAVYICTESSFPSKRLQQLASSLpkryhLEKAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 200 HVLENIAVARAYNSEHLMALII-RAGAMMSESRYAVVIVDCATAHFRNEY-TGRGDLAER--QM-KLSAFLKClakLADE 274
Cdd:cd19491 81 NFLDNIFVEHVADLETLEHCLNyQLPALLERGPIRLVVIDSIAALFRSEFdTSRSDLVERakYLrRLADHLKR---LADK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 275 YGVAVIITNQVVAQVDGGASMFQAD------------------AKKPIGGHIIAHMSTTRLYLRKGKGE----------N 326
Cdd:cd19491 158 YNLAVVVVNQVTDRFDSSSDASGLGvldylsqfssfsggvsgnRKVPALGLTWANLVNTRLMLSRTPKRitdssaasisV 237
|
250
....*....|..
gi 1972267173 327 RVAKMVQSPNLP 338
Cdd:cd19491 238 RRLEVVFSPHLP 249
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
118-352 |
4.69e-40 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 140.53 E-value: 4.69e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCqlpidmGGGEGKCMYIDTNAtFRPERIIAIAQRynmD 197
Cdd:cd01394 1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKTNICLQLAVEA------AKQGKKVVYIDTEG-LSPERFQQIAGE---R 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 198 SAHVLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEytgRGDLAERQMKLSAFLKCLAKLADEYGV 277
Cdd:cd01394 71 FESIASNIIVFEPYSFDEQGVAIQEAEKLLKSDKVDLVVVDSATALYRLE---LGDDSEANRELSRQMSKLLSIARKYDI 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972267173 278 AVIITNQVVAQVDggasmfqADAKKPIGGHIIAHMSTTRLYLRKGKGENRVAKMVQSPNLPEAE-ATYSITNHGIE 352
Cdd:cd01394 148 PVVITNQVYSDID-------DDRLKPVGGTLLEHWSKAIIRLEKSPPGLRRATLEKHRSRPEGQsAGFRITDRGIR 216
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
126-336 |
1.64e-36 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 131.67 E-value: 1.64e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 126 DRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFRPERIIAIAQRYNMDSAH----- 200
Cdd:cd19493 1 DTALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKGGLDGGVLYIDTESKFSAERLAEIAEARFPEAFSgfmee 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 201 ------VLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEYTG-RGDLAERQMKLSAFLKCLAKLAD 273
Cdd:cd19493 81 neraeeMLKRVAVVRVTTLAQLLERLPNLEEHILSSGVRLVVIDSIAALVRREFGGsDGEVTERHNALAREASSLKRLAE 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1972267173 274 EYGVAVIITNQVVAqVDGGASMFQADAKKPIgGHIIAHMSTTRLYLRKGKG-ENRVAKMVQSPN 336
Cdd:cd19493 161 EFRIAVLVTNQATT-HFGDAGDGSSGVTAAL-GDAWAHAVNTRLRLERCLLqLRRVLEIVKSPL 222
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
125-352 |
3.00e-34 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 125.22 E-value: 3.00e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 125 LDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVLCqlpidMGGGeGKCMYIDTNAtFRPERIIAIAQRynmDSAHVLEN 204
Cdd:TIGR02237 1 IDELLGGGVERGTITQIYGPPGSGKTNICMILAVNA-----ARQG-KKVVYIDTEG-LSPERFKQIAED---RPERALSN 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 205 IAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAHFRNEytGRGDLAERQMKLSAFLKCLAKLADEYGVAVIITNQ 284
Cdd:TIGR02237 71 FIVFEVFDFDEQGVAIQKTSKFIDRDSASLVVVDSFTALYRLE--LSDDRISRNRELARQLTLLLSLARKKNLAVVITNQ 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1972267173 285 VVAQVDGGASmfqadakKPIGGHIIAHMSTTRLYLRKGKGEnRVAKMVQSPNLPEAE-ATYSITNHGIE 352
Cdd:TIGR02237 149 VYTDVNNGTL-------RPLGGHLLEHWSKVILRLEKFRGR-RLATLEKHRSRPEGEsVYFRITDDGIE 209
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
136-335 |
8.55e-31 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 115.01 E-value: 8.55e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 136 GSITEVYGEYRTGKTQLCHSLAVLCQLPIDMGGGEGKCMYIDTNATFrperiiaiaqrynmdsahvleNIAVARAYNSEH 215
Cdd:cd19492 1 GKITEICGVPGVGKTQLCMQLAVNVQIPKCFGGLAGEAIYIDTEGSF---------------------NIHYFRVHDYVE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 216 LMALIIRAGAMMSE-SRYAVVIVDCATAHFRNEYTgrgDLAERQMKLSAFLKCLAKLADEYGVAVIITNQVVAQVDGGAS 294
Cdd:cd19492 60 LLALINSLPKFLEDhPKVKLIVVDSIAFPFRHDFD---DLAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTTKISEDGQ 136
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1972267173 295 MFQAdakkPIGGHIIAHMSTTRLYLRKgKGENRVAKMVQSP 335
Cdd:cd19492 137 SQLV----PALGESWSHACTTRLFLTW-DEKQRFAHLYKSP 172
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
118-356 |
2.69e-26 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 107.18 E-value: 2.69e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLG-GGIETGSITEVYGEYRTGKTQLCHSLAVLCQLpidMGGGegkCMYIDTNATFRPERiiaiAQRYNM 196
Cdd:COG0468 44 ISTGSLALDIALGvGGLPRGRIVEIYGPESSGKTTLALHAIAEAQK---AGGI---AAFIDAEHALDPEY----AKKLGV 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 197 DsahvLENIAVARAYNSEHLMALI---IRAGAMmsesryAVVIVDCATAHFRNEY----TGRGDLAERQMKLSAFLKCLA 269
Cdd:COG0468 114 D----IDNLLVSQPDTGEQALEIAetlVRSGAV------DLIVVDSVAALVPKAEiegeMGDSHVGLQARLMSQALRKLT 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 270 KLADEYGVAVIITNQVVAQVDggaSMFqADAKKPIGGHIIAHMSTTRLYLRKG----KGENRV-----AKMVQSPNLPE- 339
Cdd:COG0468 184 GAISKSNTTVIFINQLREKIG---VMF-GNPETTTGGNALKFYASVRLDIRRIgtikDGDEVIgnrtrVKVVKNKVAPPf 259
|
250
....*....|....*...
gi 1972267173 340 AEATYSIT-NHGIEDARE 356
Cdd:COG0468 260 KEAEFDIMyGEGISKEGE 277
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
130-321 |
9.65e-25 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 100.02 E-value: 9.65e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 130 GGGIETGSITEVYGEYRTGKTQLCHSLA--VLCQLPIDMgggegkcMYIDTNATFRPERIIAIAQ-RYNM--DSAHVLEN 204
Cdd:cd19489 1 GGGLRTGEITELVGESSSGKTQLCLTAAanVASRSGQNV-------LYIDTKSSFSARRLAQILKsRAQDaeEIDKALQR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 205 IAVARAYNSEHLMALIIRAGAMMS------ESRYAVVIVDCATAHFRNEYTGRGDLAERQ--MKLSAFLKclaKLADEYG 276
Cdd:cd19489 74 IRVVRVFDPYELLDLLEELRNTLSqqqenlYSRLKLVIIDSLSALISPLLGGSKHSEGHAllASLARLLK---KLAAEYQ 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1972267173 277 VAVIITNQVVAqvdGGASMFQADaKKPIGGHIIAHMSTTRLYLRK 321
Cdd:cd19489 151 IAVLVTNLTVR---GGDGGQQGS-TKPALGEYWESVPSTRLLLSR 191
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
118-352 |
5.63e-15 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 73.03 E-value: 5.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLC-HSLAVLCQLpidmggGEgKCMYIDTnaTFRPERIIAIAQRYNM 196
Cdd:COG0467 2 VPTGIPGLDELLGGGLPRGSSTLLSGPPGTGKTTLAlQFLAEGLRR------GE-KGLYVSF--EESPEQLLRRAESLGL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 197 DSAHVLEN-----IAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATAhFRNEYTGRGDLAERQMKLSAFLKclakl 271
Cdd:COG0467 73 DLEEYIESgllriIDLSPEELGLDLEELLARLREAVEEFGAKRVVIDSLSG-LLLALPDPERLREFLHRLLRYLK----- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 272 adEYGVAVIITNQvvaqvdggasmfQADAKKPIGGHIIAHMSTTRLYLRKGKGEN------RVAKMVQSPnLPEAEATYS 345
Cdd:COG0467 147 --KRGVTTLLTSE------------TGGLEDEATEGGLSYLADGVILLRYVELGGelrralSVLKMRGSA-HDRTIREFE 211
|
....*..
gi 1972267173 346 ITNHGIE 352
Cdd:COG0467 212 ITDGGIE 218
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
136-321 |
6.77e-14 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 70.07 E-value: 6.77e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 136 GSITEVYGEYRTGKTQLCHSLAVLCQLP-----IDMGGGEGKCMYIDTNATFRPERIIAI----------AQRYNMDSAH 200
Cdd:cd19490 1 GDVIEITGPSGSGKTELLYHLAARCILPsswggVPLGGLEAAVVFIDTDGRFDILRLRSIleariraaiqAANSSDDEED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 201 V-------LENIAVARAYNSEHLMA----LIIRAGAMMSESRYAVVIVDCATAHFRNEYTGRGDLAE----RQMKLSAFL 265
Cdd:cd19490 81 VeeiarecLQRLHIFRCHSSLQLLAtllsLENYLLSLSANPELGLLLIDSISAFYWQDRFSAELARAapllQEAALRAIL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972267173 266 KCLAKLADEYGVAVIITNQVVAQVDGGASMFQADAKKPIGGHIIAHMS----------TTRLYLRK 321
Cdd:cd19490 161 RELRRLRRRFQLVVIATKQALFPGKSASTDNPAANNAVSKASAPSHREylprpwqrlvTHRLVLSR 226
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
118-352 |
1.14e-09 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 57.66 E-value: 1.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVlCQLPIDmgggeGKCMYIdtnaTF--RPERIIAIAQRYN 195
Cdd:cd01124 1 VKTGIPGLDELLGGGIPKGSVTLLTGGPGTGKTLFGLQFLY-AGAKNG-----EPGLFF----TFeeSPERLLRNAKSFG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 196 MD--SAHVLENIAVARAYNSEHLMA----LIIRAGAMMSESRYAVVIVDCATAHFRneytgrgdLAERQMKLSAFLKCLA 269
Cdd:cd01124 71 WDfdEMEDEGKLIIVDAPPTEAGRFsldeLLSRILSIIKSFKAKRVVIDSLSGLRR--------AKEDQMRARRIVIALL 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 270 KLADEYGVAVIITNQvvaqvdggasMFQADAKKPIGGHIIAHMSTT--RLYLRKGKGENR----VAKMVQSPNLPeAEAT 343
Cdd:cd01124 143 NELRAAGVTTIFTSE----------MRSFLSSESAGGGDVSFIVDGviLLRYVEIEGELRrtirVLKMRGTGHDT-GTHP 211
|
....*....
gi 1972267173 344 YSITNHGIE 352
Cdd:cd01124 212 FEITDKGIV 220
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
118-351 |
1.54e-09 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 57.57 E-value: 1.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLG-GGIETGSITEVYGEYRTGKTQLC-HSLAVlCQlpiDMGggeGKCMYIDTNATFRPEriiaIAQRYN 195
Cdd:cd00983 5 IPTGSLSLDIALGiGGLPRGRIIEIYGPESSGKTTLAlHAIAE-AQ---KLG---GTAAFIDAEHALDPE----YAKKLG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 196 MDsahvLENIAVARAYNSEHLMALI---IRAGAMmsesryAVVIVDCATAHF-RNEYtgRGDLAERQMKL-----SAFLK 266
Cdd:cd00983 74 VD----IDNLLVSQPDTGEQALEIAdtlIRSGAV------DLIVVDSVAALVpKAEI--EGEMGDSHVGLqarlmSQALR 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 267 CLAKLADEYGVAVIITNQVVAQVdggASMFQADAKKPiGGHIIAHMSTTRLYLRKG----KGEN--------RVAKMVQS 334
Cdd:cd00983 142 KLTGSLSKSKTTVIFINQLREKI---GVMFGNPETTT-GGNALKFYASVRLDIRRIelikEGEDvignrtkvKVVKNKVA 217
|
250
....*....|....*..
gi 1972267173 335 PNLPEAEATYsITNHGI 351
Cdd:cd00983 218 PPFKQAEFDI-LYGEGI 233
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
89-321 |
4.46e-09 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 56.64 E-value: 4.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 89 KIMKEAMKFVQMGFTTGAEVHVKRSQLVQIR---TGSASLDRLLG-GGIETGSITEVYGEYRTGKTQLchSLAVLCQlpI 164
Cdd:pfam00154 1 KALEAALKQIEKQFGKGSIMKLGDEKKLDVEtisTGSLALDIALGiGGYPKGRIIEIYGPESSGKTTL--ALHAIAE--A 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 165 DMGGgeGKCMYIDTNATFRPeriiAIAQRYNMDsahvLENIAVARAYNSEH---LMALIIRAGAMmsesryAVVIVDCAT 241
Cdd:pfam00154 77 QKAG--GTAAFIDAEHALDP----VYAKKLGVD----IDNLLVSQPDTGEQaleIADMLVRSGAI------DLIVVDSVA 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 242 AHF-RNEYtgRGDLAERQMKLSAFL--KCLAKL---ADEYGVAVIITNQVVAQVdggASMFQADAKKPiGGHIIAHMSTT 315
Cdd:pfam00154 141 ALVpKAEI--EGEMGDSHVGLQARLmsQALRKLtgsISKSNTTVIFINQIREKI---GVMFGNPETTT-GGRALKFYASV 214
|
....*.
gi 1972267173 316 RLYLRK 321
Cdd:pfam00154 215 RLDIRR 220
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
118-352 |
4.80e-07 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 49.94 E-value: 4.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLCHSLAVlcqlpidmGG----GEgKCMYIdtnaTF--RPERIIAIA 191
Cdd:pfam06745 1 VKTGIPGLDEILKGGFPEGRVVLITGGPGTGKTIFGLQFLY--------NGalkyGE-PGVFV----TLeePPEDLRENA 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 192 QRYNMD---------------SAHVLENIAVARAYNsehLMALIIRAGAMMSESRYAVVIVDCATAHFrneYTGRGDLAE 256
Cdd:pfam06745 68 RSFGWDlekleeegklaiidaSTSGIGIAEVEDRFD---LEELIERLREAIREIGAKRVVIDSITTLF---YLLKPAVAR 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 257 RQM-KLSAFLKclakladEYGVAVIITNQVVAQVDGgasmfqadakkpIGGHIIAHMS---TTRLYLRKGKGEN----RV 328
Cdd:pfam06745 142 EILrRLKRVLK-------GLGVTAIFTSEKPSGEGG------------IGGYGVEEFIvdgVIRLDLKEIEEERvrtiEI 202
|
250 260
....*....|....*....|....
gi 1972267173 329 AKMVQSPnLPEAEATYSITNHGIE 352
Cdd:pfam06745 203 VKMRGTP-HSMKRYPFEITDNGIV 225
|
|
| recA |
PRK09519 |
intein-containing recombinase RecA; |
88-353 |
1.27e-05 |
|
intein-containing recombinase RecA;
Pssm-ID: 77219 [Multi-domain] Cd Length: 790 Bit Score: 47.01 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 88 EKIMKEAMKFVQMGFTTGAEVHV---KRSQLVQIRTGSASLDRLLG-GGIETGSITEVYGEYRTGKTQLC-HSLAvlcql 162
Cdd:PRK09519 8 EKALELAVAQIEKSYGKGSVMRLgdeARQPISVIPTGSIALDVALGiGGLPRGRVIEIYGPESSGKTTVAlHAVA----- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 163 piDMGGGEGKCMYIDTNATFRPEriiaIAQRYNMDSahvlENIAVARAYNSEHLMA---LIIRAGAMmsesryAVVIVDC 239
Cdd:PRK09519 83 --NAQAAGGVAAFIDAEHALDPD----YAKKLGVDT----DSLLVSQPDTGEQALEiadMLIRSGAL------DIVVIDS 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 240 ATAHF-RNEYTGR-GD----LAERQMklSAFLKCLAKLADEYGVAVIITNQVVAQVdggASMFqADAKKPIGGHIIAHMS 313
Cdd:PRK09519 147 VAALVpRAELEGEmGDshvgLQARLM--SQALRKMTGALNNSGTTAIFINQLRDKI---GVMF-GSPETTTGGKALKFYA 220
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1972267173 314 TTRLYLRK----GKGENRVA-----KMVQSPNLPEAEATY---SITNHGIED 353
Cdd:PRK09519 221 SVRMDVRRvetlKDGTNAVGnrtrvKVVKNKCLAEGTRIFdpvTGTTHRIED 272
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
110-285 |
1.32e-05 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 45.99 E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 110 VKRSQLVQIRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLchslavLCQLPIDMGGGEGKCMYIdtNATFRPERIIA 189
Cdd:cd01121 56 VEAEEEERISTGIGELDRVLGGGLVPGSVVLIGGDPGIGKSTL------LLQVAARLAQRGGKVLYV--SGEESLSQIKL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 190 IAQRYNMDSahvlENIAVARAYNSEHLMALIiragammSESRYAVVIVDCATAHFRNEYTGR-GDLAerQMKLSAFLkcL 268
Cdd:cd01121 128 RAERLGLGS----DNLYLLAETNLEAILAEI-------EELKPSLVVIDSIQTVYSPELTSSpGSVS--QVRECAAE--L 192
|
170
....*....|....*..
gi 1972267173 269 AKLADEYGVAVIITNQV 285
Cdd:cd01121 193 LRLAKETGIPVFLVGHV 209
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
128-282 |
3.56e-05 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 43.91 E-value: 3.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 128 LLGGGIETGSITEVYGEYRTGKTQLCHSLAV-LCQ----LPIDMGGGEGKCMYI---DTNATFRPeRIIAIAQRYNMDSA 199
Cdd:pfam13481 25 LIKGLLPAGGLGLLAGAPGTGKTTLALDLAAaVATgkpwLGGPRVPEQGKVLYVsaeGPADELRR-RLRAAGADLDLPAR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 200 HVLENIAVA-RAYNSEHLMALIIRAGAMMSES-----RYAVVIVD-CATAHFRNEYtgrgdlAERQMklSAFLKCLAKLA 272
Cdd:pfam13481 104 LLFLSLVESlPLFFLDRGGPLLDADVDALEAAleeveDPDLVVIDpLARALGGDEN------SNSDV--GRLVKALDRLA 175
|
170
....*....|
gi 1972267173 273 DEYGVAVIIT 282
Cdd:pfam13481 176 RRTGATVLLV 185
|
|
| FlaH |
COG2874 |
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility]; |
118-153 |
2.57e-04 |
|
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility];
Pssm-ID: 442121 Cd Length: 230 Bit Score: 41.74 E-value: 2.57e-04
10 20 30
....*....|....*....|....*....|....*.
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQLC 153
Cdd:COG2874 3 ISTGNDELDKRLGGGIPLGSLVLIEGENGTGKSVLS 38
|
|
| PRK09302 |
PRK09302 |
circadian clock protein KaiC; Reviewed |
112-176 |
2.79e-04 |
|
circadian clock protein KaiC; Reviewed
Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 42.56 E-value: 2.79e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972267173 112 RSQLVQIRTGSASLDRLLGGGIETGSITEVYGEYRTGKTQL-CHSLAVLCQlpidmgGGEgKCMYI 176
Cdd:PRK09302 249 RSSNERISSGVPDLDEMLGGGFFRGSIILVSGATGTGKTLLaSKFAEAACR------RGE-RCLLF 307
|
|
| PRK06067 |
PRK06067 |
flagellar accessory protein FlaH; Validated |
118-282 |
1.95e-03 |
|
flagellar accessory protein FlaH; Validated
Pssm-ID: 180381 Cd Length: 234 Bit Score: 39.18 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 118 IRTGSASLDRLLGGGIETGSITEVYGEYRTGKTqlchslaVLCQLPIDMGGGEGKCM-YIDTNATFRP-----ERI-IAI 190
Cdd:PRK06067 7 ISTGNEELDRKLGGGIPFPSLILIEGDHGTGKS-------VLSQQFVYGALKQGKKVyVITTENTSKSylkqmESVkIDI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972267173 191 AQRYNMDSAHVLENIAVARAYNSEHLMALIIRAGAMMSESRYAVVIVDCATaHFrNEYTGRGDLAErqmklsaFLKCLAK 270
Cdd:PRK06067 80 SDFFLWGYLRIFPLNTEGFEWNSTLANKLLELIIEFIKSKREDVIIIDSLT-IF-ATYAEEDDILN-------FLTEAKN 150
|
170
....*....|..
gi 1972267173 271 LADEyGVAVIIT 282
Cdd:PRK06067 151 LVDL-GKTILIT 161
|
|
| PRK08533 |
PRK08533 |
flagellar accessory protein FlaH; Reviewed |
125-157 |
4.11e-03 |
|
flagellar accessory protein FlaH; Reviewed
Pssm-ID: 181459 Cd Length: 230 Bit Score: 38.13 E-value: 4.11e-03
10 20 30
....*....|....*....|....*....|...
gi 1972267173 125 LDRLLGGGIETGSITEVYGEYRTGKTQLCHSLA 157
Cdd:PRK08533 13 LHKRLGGGIPAGSLILIEGDESTGKSILSQRLA 45
|
|
| HHH_5 |
pfam14520 |
Helix-hairpin-helix domain; |
56-94 |
6.50e-03 |
|
Helix-hairpin-helix domain;
Pssm-ID: 434010 [Multi-domain] Cd Length: 57 Bit Score: 34.39 E-value: 6.50e-03
10 20 30
....*....|....*....|....*....|....*....
gi 1972267173 56 KLKEAGYYTYESLAFTTRRELRNVKGISDQKAEKIMKEA 94
Cdd:pfam14520 17 ALLSAGIGTVEDLAEADVDELAEIPGIGEKTAQRIILEL 55
|
|
| |
