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Conserved domains on  [gi|1972230981|ref|NP_001379150|]
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palmitoyl-protein hydrolase [Caenorhabditis elegans]

Protein Classification

alpha/beta hydrolase( domain architecture ID 10491393)

alpha/beta hydrolase similar to acyl-protein thioesterase that hydrolyzes fatty acids from S-acylated cysteine residues in proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 6-221 1.62e-113

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


:

Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 323.56  E-value: 1.62e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981   6 NGNPSIVSPRGEHKGTLIFLHGLGDQGHGWADAFKTEAKHDNIKFICPHSSERPVTLNMGMRMPAWFDLFGLDPNAQEDE 85
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKTEAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  86 QGINRATQYVHQLIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSFTANN-ATPIF 164
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTkKTPIF 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1972230981 165 LGHGTDDFLVPLQFGQMSEQYIKKFNPKVELHTYRGMQHSSCGEEMRDVKTFLSAHI 221
Cdd:pfam02230 161 LIHGEEDPVVPLALGKLAKEYLKTSLNKVELKIYEGLAHSICGREMQDIKKFLSKHI 217
 
Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 6-221 1.62e-113

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 323.56  E-value: 1.62e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981   6 NGNPSIVSPRGEHKGTLIFLHGLGDQGHGWADAFKTEAKHDNIKFICPHSSERPVTLNMGMRMPAWFDLFGLDPNAQEDE 85
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKTEAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  86 QGINRATQYVHQLIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSFTANN-ATPIF 164
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTkKTPIF 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1972230981 165 LGHGTDDFLVPLQFGQMSEQYIKKFNPKVELHTYRGMQHSSCGEEMRDVKTFLSAHI 221
Cdd:pfam02230 161 LIHGEEDPVVPLALGKLAKEYLKTSLNKVELKIYEGLAHSICGREMQDIKKFLSKHI 217
YpfH COG0400
Predicted esterase [General function prediction only];
16-222 1.02e-50

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 163.15  E-value: 1.02e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  16 GEHKGTLIFLHGLGDQGHGWADAFKtEAKHDNIKFICPHSSERPVtlnmgMRMPAWFDLFGLDPnaQEDEQGINRATQYV 95
Cdd:COG0400     2 GPAAPLVVLLHGYGGDEEDLLPLAP-ELALPGAAVLAPRAPVPEG-----PGGRAWFDLSFLEG--REDEEGLAAAAEAL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  96 HQLIDAEVAA-GIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSFTANNATPIFLGHGTDDFLV 174
Cdd:COG0400    74 AAFIDELEARyGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPGEEALPAPEAALAGTPVFLAHGTQDPVI 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1972230981 175 PLQFGQMSEQYIKKFNPKVELHTYRgMQHSSCGEEMRDVKTFLSAHIA 222
Cdd:COG0400   154 PVERAREAAEALEAAGADVTYREYP-GGHEISPEELADARAWLAERLA 200
PRK10439 PRK10439
enterobactin/ferric enterobactin esterase; Provisional
 109-144 1.78e-03

enterobactin/ferric enterobactin esterase; Provisional


Pssm-ID: 236695 [Multi-domain]  Cd Length: 411  Bit Score: 38.84  E-value: 1.78e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1972230981 109 ASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLS-SF 144
Cdd:PRK10439  287 ADRTVVAGQSFGGLAALYAGLHWPERFGCVLSQSgSF 323
 
Name Accession Description Interval E-value
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
 6-221 1.62e-113

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 323.56  E-value: 1.62e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981   6 NGNPSIVSPRGEHKGTLIFLHGLGDQGHGWADAFKTEAKHDNIKFICPHSSERPVTLNMGMRMPAWFDLFGLDPNAQEDE 85
Cdd:pfam02230   1 NGCAEVVSPRDPAQATVIFLHGLGDSGHGWADAAKTEAPLPNIKFIFPHGPEIPVTLNGGMRMPAWFDLVGLSPNAKEDE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  86 QGINRATQYVHQLIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSFTANN-ATPIF 164
Cdd:pfam02230  81 AGIKNSAETIEELIDAEQKKGIPSSRIIIGGFSQGAMLALYSALTLPLPLGGIVAFSGFLPLPTKFPSHPNLVTkKTPIF 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1972230981 165 LGHGTDDFLVPLQFGQMSEQYIKKFNPKVELHTYRGMQHSSCGEEMRDVKTFLSAHI 221
Cdd:pfam02230 161 LIHGEEDPVVPLALGKLAKEYLKTSLNKVELKIYEGLAHSICGREMQDIKKFLSKHI 217
YpfH COG0400
Predicted esterase [General function prediction only];
16-222 1.02e-50

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 163.15  E-value: 1.02e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  16 GEHKGTLIFLHGLGDQGHGWADAFKtEAKHDNIKFICPHSSERPVtlnmgMRMPAWFDLFGLDPnaQEDEQGINRATQYV 95
Cdd:COG0400     2 GPAAPLVVLLHGYGGDEEDLLPLAP-ELALPGAAVLAPRAPVPEG-----PGGRAWFDLSFLEG--REDEEGLAAAAEAL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  96 HQLIDAEVAA-GIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSFTANNATPIFLGHGTDDFLV 174
Cdd:COG0400    74 AAFIDELEARyGIDPERIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPGEEALPAPEAALAGTPVFLAHGTQDPVI 153

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1972230981 175 PLQFGQMSEQYIKKFNPKVELHTYRgMQHSSCGEEMRDVKTFLSAHIA 222
Cdd:COG0400   154 PVERAREAAEALEAAGADVTYREYP-GGHEISPEELADARAWLAERLA 200
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
14-212 4.18e-16

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 73.88  E-value: 4.18e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  14 PRGEHKGTLIFLHGLGDQGHGW---ADAFkTEAKHDnikFICphsserpvtlnmgmrmpawFDL--FGLDPNAQEDEQGI 88
Cdd:COG2267    23 PAGSPRGTVVLVHGLGEHSGRYaelAEAL-AAAGYA---VLA-------------------FDLrgHGRSDGPRGHVDSF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  89 NRATQYVHQLIDAevAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGS-------FTANNA- 160
Cdd:COG2267    80 DDYVDDLRAALDA--LRARPGLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAPAYRADPLLGPSarwlralRLAEALa 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1972230981 161 ---TPIFLGHGTDDFLVPlqfGQMSEQYIKKFNPKVELHTYRGMQHSSCGEEMRD 212
Cdd:COG2267   158 ridVPVLVLHGGADRVVP---PEAARRLAARLSPDVELVLLPGARHELLNEPARE 209
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 15-220 2.13e-11

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 61.17  E-value: 2.13e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  15 RGEHKGTLIFLHGLGDQGHGWADAFKTEAKHDNIkfICPhsserpvtlnmgmrmpawfDL--FGLDPnAQEDEQGINRAT 92
Cdd:COG0596    19 AGPDGPPVVLLHGLPGSSYEWRPLIPALAAGYRV--IAP-------------------DLrgHGRSD-KPAGGYTLDDLA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  93 QYVHQLIDAevaAGIpaSRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSS---FFLQRTKFPGS--------FTANNAT 161
Cdd:COG0596    77 DDLAALLDA---LGL--ERVVLVGHSMGGMVALELAARHPERVAGLVLVDEvlaALAEPLRRPGLapealaalLRALART 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1972230981 162 -----------PIFLGHGTDDFLVPLQFGqmseQYIKKFNPKVELHTYRGMQHSSCGEE----MRDVKTFLSAH 220
Cdd:COG0596   152 dlrerlaritvPTLVIWGEKDPIVPPALA----RRLAELLPNAELVVLPGAGHFPPLEQpeafAAALRDFLARL 221
Fes COG2382
Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];
22-175 2.53e-11

Enterochelin esterase or related enzyme [Inorganic ion transport and metabolism];


Pssm-ID: 441948 [Multi-domain]  Cd Length: 314  Bit Score: 61.79  E-value: 2.53e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  22 LIFLHGLGDQGHGWADAFKTEAKHDN------IK-FICphsserpVTLNMGMRmpawfdlfgldPNAQEDEQGINRATQY 94
Cdd:COG2382   115 LYLLDGGGGDEQDWFDQGRLPTILDNliaagkIPpMIV-------VMPDGGDG-----------GDRGTEGPGNDAFERF 176

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  95 VHQ----LIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSF---------TANNAT 161
Cdd:COG2382   177 LAEelipFVEKNYRVSADPEHRAIAGLSMGGLAALYAALRHPDLFGYVGSFSGSFWWPPGDADRGgwaellaagAPKKPL 256

                         170
                  ....*....|....
gi 1972230981 162 PIFLGHGTDDFLVP 175
Cdd:COG2382   257 RFYLDVGTEDDLLE 270
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
72-204 6.11e-11

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 59.98  E-value: 6.11e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  72 FDLFGLDPNAQEDEQGINRATQYVHQLIDAEVAAGI---------PASRIAVGGFSMGGALAIYAGLTYPqklgGIVGLS 142
Cdd:COG0412    62 PDLYGRGGPGDDPDEARALMGALDPELLAADLRAALdwlkaqpevDAGRVGVVGFCFGGGLALLAAARGP----DLAAAV 137

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1972230981 143 SFF-LQRTKFPGSFTANNATPIFLGHGTDDFLVPLQFGQMSEQYIKKFNPKVELHTYRGMQHS 204
Cdd:COG0412   138 SFYgGLPADDLLDLAARIKAPVLLLYGEKDPLVPPEQVAALEAALAAAGVDVELHVYPGAGHG 200
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
106-221 1.36e-10

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 58.87  E-value: 1.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981 106 GIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSF-----FLQRTKF--------------------PGSFTANNA 160
Cdd:COG1506    89 YVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVsdlrsYYGTTREyterlmggpwedpeayaarsPLAYADKLK 168

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1972230981 161 TPIFLGHGTDDFLVPLQFGQMSEQYIKKFNPKVELHTYRGMQHSSCGEE----MRDVKTFLSAHI 221
Cdd:COG1506   169 TPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAGapdyLERILDFLDRHL 233
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
79-203 3.92e-10

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 57.19  E-value: 3.92e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  79 PNAQEDeqgINRATQYVHQLIDAevaAGIPASRIAVGGFSMGGALAIYAGLTY-------PQKLGGIVGLSSFFLQrtkf 151
Cdd:COG0657    61 PAALED---AYAALRWLRANAAE---LGIDPDRIAVAGDSAGGHLAAALALRArdrggprPAAQVLIYPVLDLTAS---- 130

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1972230981 152 PGSFTANNATPIFLGHGTDDFLVPlqfgqMSEQY---IKKFNPKVELHTYRGMQH 203
Cdd:COG0657   131 PLRADLAGLPPTLIVTGEADPLVD-----ESEALaaaLRAAGVPVELHVYPGGGH 180
COG4099 COG4099
Predicted peptidase [General function prediction only];
22-205 4.23e-10

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 57.67  E-value: 4.23e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  22 LIFLHGLGDQGHGWadafKTEAKHDNIKFICPHSSERpvtlnmgmrmpawFDLFGLDPNAQEDEQ-GINRATQYVHQLID 100
Cdd:COG4099    52 VLFLHGAGERGTDN----EKQLTHGAPKFINPENQAK-------------FPAIVLAPQCPEDDYwSDTKALDAVLALLD 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981 101 aEVAA--GIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSfflqrtkFPGSFTANNA--TPIFLGHGTDDFLVPL 176
Cdd:COG4099   115 -DLIAeyRIDPDRIYLTGLSMGGYGTWDLAARYPDLFAAAVPICG-------GGDPANAANLkkVPVWIFHGAKDDVVPV 186

                         170       180
                  ....*....|....*....|....*....
gi 1972230981 177 QFGQMSEQYIKKFNPKVELHTYRGMQHSS 205
Cdd:COG4099   187 EESRAMVEALKAAGADVKYTEYPGVGHNS 215
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 84-203 6.35e-08

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 51.45  E-value: 6.35e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  84 DEQGINRATQYVHQLidaevaAGIPASRIAVGGFSMGGALAIYAGLTYPQkLGGIVGLSSF------FLQRTKF------ 151
Cdd:COG1073    89 ERRDARAAVDYLRTL------PGVDPERIGLLGISLGGGYALNAAATDPR-VKAVILDSPFtsledlAAQRAKEargayl 161

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1972230981 152 --------------------PGSFTANNATPIFLGHGTDDFLVPLqfgQMSEQYIKKFNPKVELHTYRGMQH 203
Cdd:COG1073   162 pgvpylpnvrlasllndefdPLAKIEKISRPLLFIHGEKDEAVPF---YMSEDLYEAAAEPKELLIVPGAGH 230
DLH pfam01738
Dienelactone hydrolase family;
110-204 7.24e-08

Dienelactone hydrolase family;


Pssm-ID: 396343 [Multi-domain]  Cd Length: 213  Bit Score: 51.20  E-value: 7.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981 110 SRIAVGGFSMGGALAiYAGLTYPQKLGGIVGLSSFFLQRtkfPGSFTANNATPIFLGHGTDDFLVPLQFGQMSEQYIKKF 189
Cdd:pfam01738  96 KKVGVVGYCMGGALA-VLLAAKGPLVDAAVGFYGVGPEP---PLIEAPDIKAPILFHFGEEDHFVPADSRELIEEALKAA 171

                          90
                  ....*....|....*
gi 1972230981 190 NPKVELHTYRGMQHS 204
Cdd:pfam01738 172 NVDHQIHSYPGAGHA 186
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 93-190 8.67e-08

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 51.54  E-value: 8.67e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  93 QYVHQLIDAEVAA-GIPASRIAVGGFSMGGALAIYAGLTYPQKL--GGIV-GLssffLQRTKFPGSFTANNATPIFLGHG 168
Cdd:COG3509   116 AFIAALVDDLAARyGIDPKRVYVTGLSAGGAMAYRLACEYPDVFaaVAPVaGL----PYGAASDAACAPGRPVPVLVIHG 191

                          90       100
                  ....*....|....*....|..
gi 1972230981 169 TDDFLVPLQFGQMSEQYIKKFN 190
Cdd:COG3509   192 TADPTVPYAGAEETLAQWAALN 213
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 16-155 1.73e-06

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 47.21  E-value: 1.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  16 GEHKGTLIFLHGLGDqgHGW-----ADAFkteAKHDnikficphsserpvtlnmgmrmpawFDLFGLD-------PNAQE 83
Cdd:pfam12146   1 GEPRAVVVLVHGLGE--HSGryahlADAL---AAQG-------------------------FAVYAYDhrghgrsDGKRG 50

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1972230981  84 DEQGINRATQYVHQLIDAeVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSFFLQRTKFPGSF 155
Cdd:pfam12146  51 HVPSFDDYVDDLDTFVDK-IREEHPGLPLFLLGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPYLAPPI 121
FrmB COG0627
S-formylglutathione hydrolase FrmB [Defense mechanisms];
21-142 1.28e-04

S-formylglutathione hydrolase FrmB [Defense mechanisms];


Pssm-ID: 440392 [Multi-domain]  Cd Length: 249  Bit Score: 41.74  E-value: 1.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  21 TLIFLHGLGDQGHGW---ADAFKTEAKHdNIKFICPhsserpvtlnMGMRMPAWFDlfgldpnAQEDEQGINRATQYVHQ 97
Cdd:COG0627    35 VLYLLHGLTGTHENWtrkTGAQRLAAEL-GVIVVMP----------DGGQASFYVD-------WTQGPAGHYRWETYLTE 96

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1972230981  98 ----LIDAEVAAGIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLS 142
Cdd:COG0627    97 elppLIEANFPVSADRERRAIAGLSMGGHGALTLALRHPDLFRAVAAFS 145
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 20-196 1.49e-04

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 41.72  E-value: 1.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  20 GTLIFLHGLGDQGHGWADAFKTEAKHDnikficphsserpvtlnmgmrmpawFDLFGLD-PNAQEDEQGINRAT------ 92
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALARDG-------------------------FRVIALDlRGFGKSSRPKAQDDyrtddl 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981  93 -QYVHQLIDAevaagIPASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLSSfflqrtkfpgsftanNATPIFLGHgTDD 171
Cdd:pfam00561  56 aEDLEYILEA-----LGLEKVNLVGHSMGGLIALAYAAKYPDRVKALVLLGA---------------LDPPHELDE-ADR 114

                         170       180
                  ....*....|....*....|....*
gi 1972230981 172 FLVPLQFGQMSEQYIKKFNPKVELH 196
Cdd:pfam00561 115 FILALFPGFFDGFVADFAPNPLGRL 139
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
110-145 4.40e-04

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 40.31  E-value: 4.40e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1972230981 110 SRIAVGGFSMGGALAIYAGLTYPQkLGGIVGLSSFF 145
Cdd:COG1647    84 DKVIVIGLSMGGLLALLLAARYPD-VAGLVLLSPAL 118
YbbA COG2819
Predicted hydrolase of the alpha/beta superfamily [General function prediction only];
109-205 1.22e-03

Predicted hydrolase of the alpha/beta superfamily [General function prediction only];


Pssm-ID: 442067 [Multi-domain]  Cd Length: 250  Bit Score: 38.81  E-value: 1.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972230981 109 ASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLS-------SFFLQRTKFPGSfTANNATPIFLGHGTDDFLVPLQFG-- 179
Cdd:COG2819   129 PERTGLIGHSLGGLFSLYALLKYPDLFGRYIAISpslwwddGALLDEAEALLK-RSPLPKRLYLSVGTLEGDSMDGMVdd 207

                          90       100       110
                  ....*....|....*....|....*....|
gi 1972230981 180 --QMSEQYIKKFNP--KVELHTYRGMQHSS 205
Cdd:COG2819   208 arRLAEALKAKGYPglNVKFEVFPGETHGS 237
PRK10439 PRK10439
enterobactin/ferric enterobactin esterase; Provisional
 109-144 1.78e-03

enterobactin/ferric enterobactin esterase; Provisional


Pssm-ID: 236695 [Multi-domain]  Cd Length: 411  Bit Score: 38.84  E-value: 1.78e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1972230981 109 ASRIAVGGFSMGGALAIYAGLTYPQKLGGIVGLS-SF 144
Cdd:PRK10439  287 ADRTVVAGQSFGGLAALYAGLHWPERFGCVLSQSgSF 323
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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