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Conserved domains on  [gi|1919629429|ref|NP_001375292|]
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seizure 6-like protein 2 isoform 7 precursor [Homo sapiens]

Protein Classification

CUB domain-containing protein( domain architecture ID 13884010)

CUB (complement C1r/C1s, Uegf, Bmp1) domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 413-503 1.37e-19

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 84.77  E-value: 1.37e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 413 CGGELSEPA-GVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-----DMLTLFDGDGPSARVLAQLRGPQ 486
Cdd:cd00041     1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                          90
                  ....*....|....*..
gi 1919629429 487 PRRRLLSSGPDLTLQFQ 503
Cdd:cd00041    81 LPPPIISSGNSLTVRFR 97
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 551-714 8.87e-17

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 81.24  E-value: 8.87e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 551 GTVLTYQCEPGYELLGSDILTCQW----DLSWSAAPPACQKImTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLE 626
Cdd:PHA02927  105 GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLI 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 627 GAAMLTCYSRDtgtpkWSDRvPKCALKyePCLNPGVpENGY-QTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGhpS 705
Cdd:PHA02927  184 GNSGVLCSGGE-----WSDP-PTCQIV--KCPHPTI-SNGYlSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPG--N 252


                  ....*....
gi 1919629429 706 QWTSQPPLC 714
Cdd:PHA02927  253 TWQPELPKC 261
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 235-303 2.13e-15

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


:

Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 72.83  E-value: 2.13e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629429 235 CGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED----NDRLMVRSGGSPLSPVI 303
Cdd:cd00041     1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsYDYLEIYDGPSTSSPLL 73
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 176-231 4.07e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.00  E-value: 4.07e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629429  176 CGFPPRPAHGDVSV--TDLHPGGTATFHCDSGYQLQGEETLICLNGTrpSWNGETPSC 231
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENG--TWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
350-409 3.21e-06

Sushi repeat (SCR repeat);


:

Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.80  E-value: 3.21e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1919629429 350 CFAPF-LAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPAC 409
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRLV---GSPTITCQE--DGTWSPPFPEC 56
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 413-503 1.37e-19

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 84.77  E-value: 1.37e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 413 CGGELSEPA-GVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-----DMLTLFDGDGPSARVLAQLRGPQ 486
Cdd:cd00041     1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                          90
                  ....*....|....*..
gi 1919629429 487 PRRRLLSSGPDLTLQFQ 503
Cdd:cd00041    81 LPPPIISSGNSLTVRFR 97
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 551-714 8.87e-17

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 81.24  E-value: 8.87e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 551 GTVLTYQCEPGYELLGSDILTCQW----DLSWSAAPPACQKImTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLE 626
Cdd:PHA02927  105 GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLI 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 627 GAAMLTCYSRDtgtpkWSDRvPKCALKyePCLNPGVpENGY-QTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGhpS 705
Cdd:PHA02927  184 GNSGVLCSGGE-----WSDP-PTCQIV--KCPHPTI-SNGYlSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPG--N 252


                  ....*....
gi 1919629429 706 QWTSQPPLC 714
Cdd:PHA02927  253 TWQPELPKC 261
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 235-303 2.13e-15

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 72.83  E-value: 2.13e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629429 235 CGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED----NDRLMVRSGGSPLSPVI 303
Cdd:cd00041     1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsYDYLEIYDGPSTSSPLL 73
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 530-586 6.46e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 6.46e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1919629429 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 586
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CUB pfam00431
CUB domain;
413-503 1.15e-11

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 61.93  E-value: 1.15e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 413 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-----GDMLTLFDGDGPSARVLAQLRGPQP 487
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDhdecgYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90
                  ....*....|....*.
gi 1919629429 488 RRRLLSSGPDLTLQFQ 503
Cdd:pfam00431  81 PEDIVSSSNQMTIKFV 96
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 530-585 2.08e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.46  E-value: 2.08e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1919629429  530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 585
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 422-503 2.20e-11

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 60.87  E-value: 2.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429  422 GVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-----DMLTLFDGDGPSARVLAQLRGPQ-PRRRLLSSG 495
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEaPPPVISSSS 80


                   ....*...
gi 1919629429  496 PDLTLQFQ 503
Cdd:smart00042  81 NSLTLTFV 88
Sushi pfam00084
Sushi repeat (SCR repeat);
530-585 1.00e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.51  E-value: 1.00e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1919629429 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 585
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 176-231 4.07e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.00  E-value: 4.07e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629429  176 CGFPPRPAHGDVSV--TDLHPGGTATFHCDSGYQLQGEETLICLNGTrpSWNGETPSC 231
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENG--TWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 176-231 7.63e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.16  E-value: 7.63e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1919629429 176 CGFPPRPAHGDV--SVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTrpsWNGETPSC 231
Cdd:cd00033     1 CPPPPVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGG---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
176-231 2.48e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.96  E-value: 2.48e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629429 176 CGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICLNGtrPSWNGETPSC 231
Cdd:pfam00084   1 CPPPPDIPNGKVSATKneYNYGASVSYECDPGYRLVGSPTITCQED--GTWSPPFPEC 56
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 245-303 4.32e-08

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 51.62  E-value: 4.32e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629429  245 GRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN----DRLMVRSGGSPLSPVI 303
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASSPLL 63
Sushi pfam00084
Sushi repeat (SCR repeat);
350-409 3.21e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.80  E-value: 3.21e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1919629429 350 CFAPF-LAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPAC 409
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRLV---GSPTITCQE--DGTWSPPFPEC 56
CUB pfam00431
CUB domain;
235-303 4.85e-05

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 43.05  E-value: 4.85e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629429 235 CGGTIHNATlGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED----NDRLMVRSGGSPLSPVI 303
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHdecgYDYVEIRDGPSASSPLL 72
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 353-410 1.86e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.14  E-value: 1.86e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629429 353 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPACK 410
Cdd:cd00033     5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLV---GSSTITCTE--NGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 353-409 7.60e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 38.28  E-value: 7.60e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1919629429  353 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPAC 409
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLI---GSSTITCLE--NGTWSPPPPTC 56
 
Name Accession Description Interval E-value
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 413-503 1.37e-19

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 84.77  E-value: 1.37e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 413 CGGELSEPA-GVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-----DMLTLFDGDGPSARVLAQLRGPQ 486
Cdd:cd00041     1 CGGTLTASTsGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsyDYLEIYDGPSTSSPLLGRFCGST 80

                          90
                  ....*....|....*..
gi 1919629429 487 PRRRLLSSGPDLTLQFQ 503
Cdd:cd00041    81 LPPPIISSGNSLTVRFR 97
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 551-714 8.87e-17

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 81.24  E-value: 8.87e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 551 GTVLTYQCEPGYELLGSDILTCQW----DLSWSAAPPACQKImTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLE 626
Cdd:PHA02927  105 GSSITYSCNSGYQLIGESKSYCELgstgSMVWNPEAPICESV-KCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLI 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 627 GAAMLTCYSRDtgtpkWSDRvPKCALKyePCLNPGVpENGY-QTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGhpS 705
Cdd:PHA02927  184 GNSGVLCSGGE-----WSDP-PTCQIV--KCPHPTI-SNGYlSSGFKRSYSYNDNVDFKCKYGYKLSGSSSSTCSPG--N 252


                  ....*....
gi 1919629429 706 QWTSQPPLC 714
Cdd:PHA02927  253 TWQPELPKC 261
CUB cd00041
CUB domain; extracellular domain; present in proteins mostly known to be involved in ...
 235-303 2.13e-15

CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.


Pssm-ID: 238001 [Multi-domain]  Cd Length: 113  Bit Score: 72.83  E-value: 2.13e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629429 235 CGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED----NDRLMVRSGGSPLSPVI 303
Cdd:cd00041     1 CGGTLTASTSGTISSPNYPNNYPNNLNCVWTIEAPPGYRIRLTFEDFDLESSpncsYDYLEIYDGPSTSSPLL 73
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 551-723 1.06e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 71.99  E-value: 1.06e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 551 GTVLTYQCEPGY--ELLGSDILTCQWDlSWSAAPPACQKimTCADPGEIANGHRTASDAGFpvGSHVQYRCLPGYSLEGA 628
Cdd:PHA02927   47 GDTIEYLCLPGYrkQKMGPIYAKCTGT-GWTLFNQCIKR--RCPSPRDIDNGQLDIGGVDF--GSSITYSCNSGYQLIGE 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 629 AMLTCYSRDTGTPKWSDRVPKCalKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGhpsQWt 708
Cdd:PHA02927  122 SKSYCELGSTGSMVWNPEAPIC--ESVKCQSPPSISNGRHNGYEDFYTDGSVVTYSCNSGYSLIGNSGVLCSGG---EW- 195

                         170
                  ....*....|....*
gi 1919629429 709 SQPPLCKVTQTTDPS 723
Cdd:PHA02927  196 SDPPTCQIVKCPHPT 210
PHA02639 PHA02639
EEV host range protein; Provisional
 587-725 2.71e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 71.23  E-value: 2.71e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 587 KIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYsRDTGTPKWSDRVPKCALKyePCLNPGVPENG 666
Cdd:PHA02639   18 KSIYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCI-KDKNNAIWSNKAPFCMLK--ECNDPPSIING 94

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629429 667 YQTLYKHHYQAGESLRFFCYE----GFELIGEVTITCVpgHPSQWTSQPPLCKVTQTTDPSRQ 725
Cdd:PHA02639   95 KIYNKREMYKVGDEIYYVCNEhkgvQYSLVGNEKITCI--QDKSWKPDPPICKMINCRFPALQ 155
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 530-586 6.46e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 6.46e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1919629429 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQ 586
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 657-715 9.36e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.55  E-value: 9.36e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1919629429 657 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGhpSQWTSQPPLCK 715
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTEN--GGWSPPPPTCE 57
CUB pfam00431
CUB domain;
413-503 1.15e-11

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 61.93  E-value: 1.15e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 413 CGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVRE-----GDMLTLFDGDGPSARVLAQLRGPQP 487
Cdd:pfam00431   1 CGGVLTDSSGSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDhdecgYDYVEIRDGPSASSPLLGRFCGSGI 80

                          90
                  ....*....|....*.
gi 1919629429 488 RRRLLSSGPDLTLQFQ 503
Cdd:pfam00431  81 PEDIVSSSNQMTIKFV 96
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 530-585 2.08e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.46  E-value: 2.08e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1919629429  530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 585
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 422-503 2.20e-11

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 60.87  E-value: 2.20e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429  422 GVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREG-----DMLTLFDGDGPSARVLAQLRGPQ-PRRRLLSSG 495
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSdnceyDYVEIYDGPSASSPLLGRFCGSEaPPPVISSSS 80


                   ....*...
gi 1919629429  496 PDLTLQFQ 503
Cdd:smart00042  81 NSLTLTFV 88
Sushi pfam00084
Sushi repeat (SCR repeat);
530-585 1.00e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 57.51  E-value: 1.00e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1919629429 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPAC 585
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 591-650 1.18e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.54  E-value: 1.18e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429  591 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCysrdTGTPKWSDRVPKC 650
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITC----LENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 657-714 1.26e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.54  E-value: 1.26e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629429  657 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGhpSQWTSQPPLC 714
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCLEN--GTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 591-650 1.36e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.47  E-value: 1.36e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 591 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCysrdTGTPKWSDRVPKC 650
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITC----TENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 176-231 4.07e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.00  E-value: 4.07e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629429  176 CGFPPRPAHGDVSV--TDLHPGGTATFHCDSGYQLQGEETLICLNGTrpSWNGETPSC 231
Cdd:smart00032   1 CPPPPDIENGTVTSssGTYSYGDTVTYSCDPGYTLIGSSTITCLENG--TWSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 551-721 6.75e-10

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 61.22  E-value: 6.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 551 GTVLTYQCEPGYELLGSDILTCQWDLS---WSAAPPACQkIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLP----GY 623
Cdd:PHA02639   43 GKLIEYTCNTDYALIGDRFRTCIKDKNnaiWSNKAPFCM-LKECNDPPSIINGKIYNKREMYKVGDEIYYVCNEhkgvQY 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 624 SLEGAAMLTCysrdTGTPKWSDRVPKCalKYEPCLNPGVPE---NGYQTLYKHHYQAgeSLRFFCYEGFELIGEVTITCv 700
Cdd:PHA02639  122 SLVGNEKITC----IQDKSWKPDPPIC--KMINCRFPALQNgyiNGIPSNKKFYYKT--RVGFSCKSGFDLVGEKYSTC- 192

                         170       180
                  ....*....|....*....|.
gi 1919629429 701 pGHPSQWTSQPPLCKVTQTTD 721
Cdd:PHA02639  193 -NINATWFPSIPTCVRNKPID 212
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 176-231 7.63e-10

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 55.16  E-value: 7.63e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1919629429 176 CGFPPRPAHGDV--SVTDLHPGGTATFHCDSGYQLQGEETLICL-NGTrpsWNGETPSC 231
Cdd:cd00033     1 CPPPPVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSSTITCTeNGG---WSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 554-714 9.07e-10

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 60.39  E-value: 9.07e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 554 LTYQCEPGYEllgSDILTCQwDLSWSAAPpACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRC----LPGYSLEGAA 629
Cdd:PHA02831   46 LEYKCNNNFD---KVFVTCN-NGSWSTKN-MCIGKRNCKDPVTILNGYIKNKKDQYSFGDSVTYACkvnkLEKYSIVGNE 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 630 MLTCYSRdtgtpKWSDRVPKCAL---KYePCLnpgvpENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCvpGHPSQ 706
Cdd:PHA02831  121 TVKCINK-----QWVPKYPVCKLircKY-PAL-----QNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTC--DINSI 187


                  ....*...
gi 1919629429 707 WTSQPPLC 714
Cdd:PHA02831  188 WYPGIPKC 195
Sushi pfam00084
Sushi repeat (SCR repeat);
176-231 2.48e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.96  E-value: 2.48e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629429 176 CGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICLNGtrPSWNGETPSC 231
Cdd:pfam00084   1 CPPPPDIPNGKVSATKneYNYGASVSYECDPGYRLVGSPTITCQED--GTWSPPFPEC 56
CUB smart00042
Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found ...
 245-303 4.32e-08

Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein; This domain is found mostly among developmentally-regulated proteins. Spermadhesins contain only this domain.


Pssm-ID: 214483 [Multi-domain]  Cd Length: 102  Bit Score: 51.62  E-value: 4.32e-08
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629429  245 GRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDN----DRLMVRSGGSPLSPVI 303
Cdd:smart00042   1 GTITSPNYPQSYPNNLDCVWTIRAPPGYRIELQFTDFDLESSDnceyDYVEIYDGPSASSPLL 63
Sushi pfam00084
Sushi repeat (SCR repeat);
591-650 9.32e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.42  E-value: 9.32e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 591 CADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCysrdTGTPKWSDRVPKC 650
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITC----QEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
657-714 5.83e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.11  E-value: 5.83e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629429 657 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGhpSQWTSQPPLC 714
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQED--GTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
350-409 3.21e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 44.80  E-value: 3.21e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1919629429 350 CFAPF-LAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPAC 409
Cdd:pfam00084   1 CPPPPdIPNGKVSATKNEYNYGASVSYECDPGYRLV---GSPTITCQE--DGTWSPPFPEC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 599-722 7.86e-06

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 48.11  E-value: 7.86e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 599 NGHRTASDAGFPVGSHVQYRCLPGYSLEgaAMLTCYSRDTGTpKWSdRVPKCALKYepCLNPGVPENGYQTLYKHHYqaG 678
Cdd:PHA02927   34 NSVETDANANYNIGDTIEYLCLPGYRKQ--KMGPIYAKCTGT-GWT-LFNQCIKRR--CPSPRDIDNGQLDIGGVDF--G 105

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1919629429 679 ESLRFFCYEGFELIGEVTITCVPGHPSQ--WTSQPPLCKVTQTTDP 722
Cdd:PHA02927  106 SSITYSCNSGYQLIGESKSYCELGSTGSmvWNPEAPICESVKCQSP 151
PHA02817 PHA02817
EEV Host range protein; Provisional
 550-659 8.76e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 47.63  E-value: 8.76e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 550 RGTVLTYQCEPG-----YELLGSDILTCQWDLSWSAAPPACqKIMTCADPGeIANGHRTA--SDAGFPVGSHVQYRCLPG 622
Cdd:PHA02817   44 IGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVC-KIIRCRFPA-LQNGFVNGipDSKKFYYESEVSFSCKPG 121

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1919629429 623 YSLEGAAMLTCYSRDTgtpkWSDRVPKCaLKYEPCLN 659
Cdd:PHA02817  122 FVLIGTKYSVCGINSS----WIPKVPIC-SRDNITYN 153
CUB pfam00431
CUB domain;
235-303 4.85e-05

CUB domain;


Pssm-ID: 395345 [Multi-domain]  Cd Length: 110  Bit Score: 43.05  E-value: 4.85e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629429 235 CGGTIHNATlGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDED----NDRLMVRSGGSPLSPVI 303
Cdd:pfam00431   1 CGGVLTDSS-GSISSPNYPNPYPPNKDCVWLIRAPPGFRVKLTFQDFELEDHdecgYDYVEIRDGPSASSPLL 72
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 551-650 7.49e-05

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 45.46  E-value: 7.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 551 GTVLTYQCEPGYELLGSDILTCQWDlSWSAAPPACQKimtCADPgEIANGhrTASDAGFPVGSHVQYRCLPGYSLEGAAM 630
Cdd:PHA02954  150 GEHITINCDVGYEVIGASYISCTAN-SWNVIPSCQQK---CDIP-SLSNG--LISGSTFSIGGVIHLSCKSGFTLTGSPS 222

                          90       100
                  ....*....|....*....|
gi 1919629429 631 LTCYSrdtgtPKWSDRVPKC 650
Cdd:PHA02954  223 STCID-----GKWNPVLPIC 237
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 353-410 1.86e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 40.14  E-value: 1.86e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1919629429 353 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPACK 410
Cdd:cd00033     5 PVPENGTVTGSKGSYSYGSTVTYSCNEGYTLV---GSSTITCTE--NGGWSPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 591-714 2.24e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 43.39  E-value: 2.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 591 CADPGEIANGHRTASDAGFPVGSHVQYRC------LPgYSLEGAAMLTCySRDTgtpKWSDRVPKCAL---KYePCLNPG 661
Cdd:PHA02817   24 CCYPPSIKNGYIYNKKTEYNIGSNVTFFCgnntrgVR-YTLVGEKNIIC-EKDG---KWNKEFPVCKIircRF-PALQNG 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1919629429 662 VPeNGYQTLYKHHYQagESLRFFCYEGFELIGEVTITCvpGHPSQWTSQPPLC 714
Cdd:PHA02817   98 FV-NGIPDSKKFYYE--SEVSFSCKPGFVLIGTKYSVC--GINSSWIPKVPIC 145
PHA02817 PHA02817
EEV Host range protein; Provisional
 650-725 5.43e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 42.24  E-value: 5.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1919629429 650 CALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEG-----FELIGEVTITCvpGHPSQWTSQPPLCKVTQTTDPSR 724
Cdd:PHA02817   17 SLCDLNKCCYPPSIKNGYIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIIC--EKDGKWNKEFPVCKIIRCRFPAL 94


                  .
gi 1919629429 725 Q 725
Cdd:PHA02817   95 Q 95
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 353-409 7.60e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 38.28  E-value: 7.60e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1919629429  353 PFLAHGNVTTTDPEYRPGALATFSCLPGYALEppgPPNAIECVDptEPHWNDTEPAC 409
Cdd:smart00032   5 PDIENGTVTSSSGTYSYGDTVTYSCDPGYTLI---GSSTITCLE--NGTWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 657-725 1.91e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 40.75  E-value: 1.91e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629429 657 CLNPGVPENGYQTLYKHHYQAGESLRFFC----YEGFELIGEVTITCVPGhpsQWTSQPPLCKVTQTTDPSRQ 725
Cdd:PHA02831   78 CKDPVTILNGYIKNKKDQYSFGDSVTYACkvnkLEKYSIVGNETVKCINK---QWVPKYPVCKLIRCKYPALQ 147
PHA02639 PHA02639
EEV host range protein; Provisional
 657-728 3.94e-03

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 40.03  E-value: 3.94e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1919629429 657 CLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPG-HPSQWTSQPPLCKVTQTTDPSRQLEG 728
Cdd:PHA02639   22 CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDkNNAIWSNKAPFCMLKECNDPPSIING 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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