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Conserved domains on  [gi|1917203636|ref|NP_001374955|]
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zinc finger protein 107 isoform e [Homo sapiens]

Protein Classification

KRAB domain-containing zinc finger protein( domain architecture ID 12204268)

KRAB (Kruppel-associated box) domain-containing zinc finger protein (KRAB-ZFP) plays important roles in cell differentiation and organ development, and in regulating viral replication and transcription

CATH:  3.30.160.60
Gene Ontology:  GO:0003700|GO:0046872
PubMed:  22803940
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
9-69 8.25e-32

krueppel associated box;


:

Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 117.69  E-value: 8.25e-32
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1917203636    9 LTFKDVAIEFSLEEWQCLDTAQRDLYRNVLLENYRNLVFLGIAVSKPYLITCLEQKKEPWN 69
Cdd:smart00349   1 VTFEDVAVYFTQEEWEQLDPAQKNLYRDVMLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
512-824 5.12e-13

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 72.42  E-value: 5.12e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 512 KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKC--EECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQ--SYQLTR 587
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSkaSSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 588 HKIVHTKEKLNkceEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFS 667
Cdd:COG5048   112 SSSSNSNDNNL---LSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLI 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 668 NITNHkiiyTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAF 747
Cdd:COG5048   189 SSNVS----TSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSS 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 748 NLSSTLTAHKKIHTGE-------KPYKCEECGKAFNQSSNLTTHK--KIHTSE--KPYKCEE--CGKSFNQFSSLNIHKI 814
Cdd:COG5048   265 LPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHIL 344

                         330
                  ....*....|
gi 1917203636 815 IHTGEKPYKC 824
Cdd:COG5048   345 LHTSISPAKE 354
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
204-582 2.84e-11

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.64  E-value: 2.84e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 204 NSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQS--SQLTRHKIIHTEEKPNKCEECGKAFKQA------- 274
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKSLPLSNSKassssls 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 275 -----------------SHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHK 337
Cdd:COG5048   112 ssssnsndnnllsshslPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 338 RIHAGEKPYKCKECGRA--FNISSNLNKQEKIHTGGKLNKC-EECDKAFNRSLKLTAHKKILMEEKPykceECGKVFNQF 414
Cdd:COG5048   192 VSTSIPSSSENSPLSSSysIPSSSSDQNLENSSSSLPLTTNsQLSPKSLLSQSPSSLSSSDSSSSAS----ESPRSSLPT 267

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 415 STLTRHKIIHTGE-------KPYKCKECGKAFNQSSNLTEHK--KIHTAE--KSYKCEE--CGKAFNQHSNLINHRKIYS 481
Cdd:COG5048   268 ASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 482 GEKPYKC--EECGKAFNRSST-----LTRHKKIHTGEKPYKCE--ECDRAFSQSSNLTEHKKIHTGEKP--YKCEECGKA 550
Cdd:COG5048   348 SISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKS 427

                         410       420       430
                  ....*....|....*....|....*....|..
gi 1917203636 551 FNRFSTLTKHKRIHTGEKPYKCEECGKAFNQS 582
Cdd:COG5048   428 FNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459
 
Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
9-69 8.25e-32

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 117.69  E-value: 8.25e-32
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1917203636    9 LTFKDVAIEFSLEEWQCLDTAQRDLYRNVLLENYRNLVFLGIAVSKPYLITCLEQKKEPWN 69
Cdd:smart00349   1 VTFEDVAVYFTQEEWEQLDPAQKNLYRDVMLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
KRAB pfam01352
KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc ...
 8-49 1.46e-21

KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation.


Pssm-ID: 460171  Cd Length: 42  Bit Score: 87.91  E-value: 1.46e-21
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1917203636   8 PLTFKDVAIEFSLEEWQCLDTAQRDLYRNVLLENYRNLVFLG 49
Cdd:pfam01352   1 SVTFEDVAVDFTQEEWALLDPAQRNLYRDVMLENYRNLVSLG 42
KRAB_A-box cd07765
KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression ...
 9-48 2.10e-19

KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression module, found in a subgroup of the zinc finger proteins (ZFPs) of the C2H2 family, KRAB-ZFPs. KRAB-ZFPs comprise the largest group of transcriptional regulators in mammals, and are only found in tetrapods. These proteins have been shown to play important roles in cell differentiation and organ development, and in regulating viral replication and transcription. A KRAB domain may consist of an A-box, or of an A-box plus either a B-box, a divergent B-box (b), or a C-box. Only the A-box is included in this model. The A-box is needed for repression, the B- and C- boxes are not. KRAB-ZFPs have one or two KRAB domains at their amino-terminal end, and multiple C2H2 zinc finger motifs at their C-termini. Some KRAB-ZFPs also contain a SCAN domain which mediates homo- and hetero-oligomerization. The KRAB domain is a protein-protein interaction module which represses transcription through recruiting corepressors. A key mechanism appears to be the following: KRAB-AFPs tethered to DNA recruit, via their KRAB domain, the repressor KAP1 (KRAB-associated protein-1, also known as transcription intermediary factor 1 beta , KRAB-A interacting protein , and tripartite motif protein 28). The KAP1/ KRAB-AFP complex in turn recruits the heterochromatin protein 1 (HP1) family, and other chromatin modulating proteins, leading to transcriptional repression through heterochromatin formation.


Pssm-ID: 143639  Cd Length: 40  Bit Score: 81.83  E-value: 2.10e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1917203636   9 LTFKDVAIEFSLEEWQCLDTAQRDLYRNVLLENYRNLVFL 48
Cdd:cd07765     1 VTFEDVAVYFSQEEWELLDPAQRDLYRDVMLENYENLVSL 40
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
512-824 5.12e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 72.42  E-value: 5.12e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 512 KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKC--EECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQ--SYQLTR 587
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSkaSSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 588 HKIVHTKEKLNkceEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFS 667
Cdd:COG5048   112 SSSSNSNDNNL---LSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLI 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 668 NITNHkiiyTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAF 747
Cdd:COG5048   189 SSNVS----TSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSS 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 748 NLSSTLTAHKKIHTGE-------KPYKCEECGKAFNQSSNLTTHK--KIHTSE--KPYKCEE--CGKSFNQFSSLNIHKI 814
Cdd:COG5048   265 LPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHIL 344

                         330
                  ....*....|
gi 1917203636 815 IHTGEKPYKC 824
Cdd:COG5048   345 LHTSISPAKE 354
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
204-582 2.84e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.64  E-value: 2.84e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 204 NSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQS--SQLTRHKIIHTEEKPNKCEECGKAFKQA------- 274
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKSLPLSNSKassssls 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 275 -----------------SHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHK 337
Cdd:COG5048   112 ssssnsndnnllsshslPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 338 RIHAGEKPYKCKECGRA--FNISSNLNKQEKIHTGGKLNKC-EECDKAFNRSLKLTAHKKILMEEKPykceECGKVFNQF 414
Cdd:COG5048   192 VSTSIPSSSENSPLSSSysIPSSSSDQNLENSSSSLPLTTNsQLSPKSLLSQSPSSLSSSDSSSSAS----ESPRSSLPT 267

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 415 STLTRHKIIHTGE-------KPYKCKECGKAFNQSSNLTEHK--KIHTAE--KSYKCEE--CGKAFNQHSNLINHRKIYS 481
Cdd:COG5048   268 ASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 482 GEKPYKC--EECGKAFNRSST-----LTRHKKIHTGEKPYKCE--ECDRAFSQSSNLTEHKKIHTGEKP--YKCEECGKA 550
Cdd:COG5048   348 SISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKS 427

                         410       420       430
                  ....*....|....*....|....*....|..
gi 1917203636 551 FNRFSTLTKHKRIHTGEKPYKCEECGKAFNQS 582
Cdd:COG5048   428 FNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459
zf-H2C2_2 pfam13465
Zinc-finger double domain;
528-553 2.95e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 2.95e-04
                          10        20
                  ....*....|....*....|....*.
gi 1917203636 528 NLTEHKKIHTGEKPYKCEECGKAFNR 553
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
221-245 4.32e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 4.32e-04
                          10        20
                  ....*....|....*....|....*
gi 1917203636 221 LTKHKRIHTGEKPYKCEECGKAFNQ 245
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
9-69 8.25e-32

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 117.69  E-value: 8.25e-32
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1917203636    9 LTFKDVAIEFSLEEWQCLDTAQRDLYRNVLLENYRNLVFLGIAVSKPYLITCLEQKKEPWN 69
Cdd:smart00349   1 VTFEDVAVYFTQEEWEQLDPAQKNLYRDVMLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
KRAB pfam01352
KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc ...
 8-49 1.46e-21

KRAB box; The KRAB domain (or Kruppel-associated box) is present in about a third of zinc finger proteins containing C2H2 fingers. The KRAB domain is found to be involved in protein-protein interactions. The KRAB domain is generally encoded by two exons. The regions coded by the two exons are known as KRAB-A and KRAB-B. The A box plays an important role in repression by binding to corepressors, while the B box is thought to enhance this repression brought about by the A box. KRAB-containing proteins are thought to have critical functions in cell proliferation and differentiation, apoptosis and neoplastic transformation.


Pssm-ID: 460171  Cd Length: 42  Bit Score: 87.91  E-value: 1.46e-21
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1917203636   8 PLTFKDVAIEFSLEEWQCLDTAQRDLYRNVLLENYRNLVFLG 49
Cdd:pfam01352   1 SVTFEDVAVDFTQEEWALLDPAQRNLYRDVMLENYRNLVSLG 42
KRAB_A-box cd07765
KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression ...
 9-48 2.10e-19

KRAB (Kruppel-associated box) domain -A box; The KRAB domain is a transcription repression module, found in a subgroup of the zinc finger proteins (ZFPs) of the C2H2 family, KRAB-ZFPs. KRAB-ZFPs comprise the largest group of transcriptional regulators in mammals, and are only found in tetrapods. These proteins have been shown to play important roles in cell differentiation and organ development, and in regulating viral replication and transcription. A KRAB domain may consist of an A-box, or of an A-box plus either a B-box, a divergent B-box (b), or a C-box. Only the A-box is included in this model. The A-box is needed for repression, the B- and C- boxes are not. KRAB-ZFPs have one or two KRAB domains at their amino-terminal end, and multiple C2H2 zinc finger motifs at their C-termini. Some KRAB-ZFPs also contain a SCAN domain which mediates homo- and hetero-oligomerization. The KRAB domain is a protein-protein interaction module which represses transcription through recruiting corepressors. A key mechanism appears to be the following: KRAB-AFPs tethered to DNA recruit, via their KRAB domain, the repressor KAP1 (KRAB-associated protein-1, also known as transcription intermediary factor 1 beta , KRAB-A interacting protein , and tripartite motif protein 28). The KAP1/ KRAB-AFP complex in turn recruits the heterochromatin protein 1 (HP1) family, and other chromatin modulating proteins, leading to transcriptional repression through heterochromatin formation.


Pssm-ID: 143639  Cd Length: 40  Bit Score: 81.83  E-value: 2.10e-19
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1917203636   9 LTFKDVAIEFSLEEWQCLDTAQRDLYRNVLLENYRNLVFL 48
Cdd:cd07765     1 VTFEDVAVYFSQEEWELLDPAQRDLYRDVMLENYENLVSL 40
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
512-824 5.12e-13

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 72.42  E-value: 5.12e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 512 KPYKCEECDRAFSQSSNLTEHKKIHTGEKPYKC--EECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQ--SYQLTR 587
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSkaSSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 588 HKIVHTKEKLNkceEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFS 667
Cdd:COG5048   112 SSSSNSNDNNL---LSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLI 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 668 NITNHkiiyTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAF 747
Cdd:COG5048   189 SSNVS----TSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSS 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 748 NLSSTLTAHKKIHTGE-------KPYKCEECGKAFNQSSNLTTHK--KIHTSE--KPYKCEE--CGKSFNQFSSLNIHKI 814
Cdd:COG5048   265 LPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHIL 344

                         330
                  ....*....|
gi 1917203636 815 IHTGEKPYKC 824
Cdd:COG5048   345 LHTSISPAKE 354
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
260-729 1.78e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 70.49  E-value: 1.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 260 KPNKCEECGKAFKQASHLTIHKIIHTGEKPY--KYEECGKVFSQSSHLTTQKILHTGENLYKC-KECGKAFNLFSNLTNH 336
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSqcSYSGCDKSFSRPLELSRHLRTHHNNPSDLNsKSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 337 KRIHAGEKPYKCKECGrafnISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKltAHKKILMEEKPYKCEECGKVFNQFST 416
Cdd:COG5048   112 SSSSNSNDNNLLSSHS----LPPSSRDPQLPDLLSISNLRNNPLPGNNSSSV--NTPQSNSLHPPLPANSLSKDPSSNLS 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 417 LTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFN 496
Cdd:COG5048   186 LLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 497 RSSTLTRHKKIHTGE-------KPYKCEECDRAFSQSSNLTEHK--KIHTGE--KPYKCEE--CGKAFNRFSTLTKHKRI 563
Cdd:COG5048   266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 564 HTGEKPYKCeecgkafnqsyqltrhKIVHTKEKLNKCEEfGKAFKQSSHRTIHKIIHTGEKPYKCEEhgKVFNQSSNLTT 643
Cdd:COG5048   346 HTSISPAKE----------------KLLNSSSKFSPLLN-NEPPQSLQQYKDLKNDKKSETLSNSCI--RNFKRDSNLSL 406

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 644 QKIIHTGENLYKFeehgkafnlfsnitnhkiiytgekphKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSS 723
Cdd:COG5048   407 HIITHLSFRPYNC--------------------------KNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLD 460


                  ....*.
gi 1917203636 724 TLNRHK 729
Cdd:COG5048   461 LSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
385-835 3.34e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 69.72  E-value: 3.34e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 385 RSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKC--KECGKAFNQSSNLTEHKKIHTAEKSYKCE- 461
Cdd:COG5048    17 SSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSk 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 462 ECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEkp 541
Cdd:COG5048    97 SLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN-- 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 542 ykcEECGKAFNRFSTLTKHKRIHTGEKPYKCEECgkafNQSYQLTRHKIVHTKEklnkceefgkafKQSSHRTIHKIIHT 621
Cdd:COG5048   175 ---SLSKDPSSNLSLLISSNVSTSIPSSSENSPL----SSSYSIPSSSSDQNLE------------NSSSSLPLTTNSQL 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 622 GEKPYKCEEHGKVFNQSSNLTTQKiihTGENLYKFEEHGKAFNLFSNITNHKIIYTgekPHKCEECGKAYNRFSNLTIHK 701
Cdd:COG5048   236 SPKSLLSQSPSSLSSSDSSSSASE---SPRSSLPTASSQSSSPNESDSSSEKGFSL---PIKSKQCNISFSRSSPLTRHL 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 702 R--IHTGE--KPYQCAE--CGKAFNCSSTLNRHKIIHTGEKPYKCKEC-------GKAFNLSSTLTAHKKIHTGEKPYKC 768
Cdd:COG5048   310 RsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSET 389

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1917203636 769 E--ECGKAFNQSSNLTTHKKIHTSEKP--YKCEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSS 835
Cdd:COG5048   390 LsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLD 460
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
204-582 2.84e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.64  E-value: 2.84e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 204 NSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQS--SQLTRHKIIHTEEKPNKCEECGKAFKQA------- 274
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKSLPLSNSKassssls 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 275 -----------------SHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHK 337
Cdd:COG5048   112 ssssnsndnnllsshslPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 338 RIHAGEKPYKCKECGRA--FNISSNLNKQEKIHTGGKLNKC-EECDKAFNRSLKLTAHKKILMEEKPykceECGKVFNQF 414
Cdd:COG5048   192 VSTSIPSSSENSPLSSSysIPSSSSDQNLENSSSSLPLTTNsQLSPKSLLSQSPSSLSSSDSSSSAS----ESPRSSLPT 267

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 415 STLTRHKIIHTGE-------KPYKCKECGKAFNQSSNLTEHK--KIHTAE--KSYKCEE--CGKAFNQHSNLINHRKIYS 481
Cdd:COG5048   268 ASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 482 GEKPYKC--EECGKAFNRSST-----LTRHKKIHTGEKPYKCE--ECDRAFSQSSNLTEHKKIHTGEKP--YKCEECGKA 550
Cdd:COG5048   348 SISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKS 427

                         410       420       430
                  ....*....|....*....|....*....|..
gi 1917203636 551 FNRFSTLTKHKRIHTGEKPYKCEECGKAFNQS 582
Cdd:COG5048   428 FNRHYNLIPHKKIHTNHAPLLCSILKSFRRDL 459
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
484-853 2.26e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.95  E-value: 2.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 484 KPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKC--EECDRAFSQSSNLTEHKKIHTGEKPYkcEECGKAFNRFSTLTKHK 561
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSD--LNSKSLPLSNSKASSSS 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 562 RIHTGEKPYKCE-ECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHgkvFNQSSN 640
Cdd:COG5048   110 LSSSSSNSNDNNlLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDP---SSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 641 LTTQKIIHTGENLYKFEEHGKaFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFN 720
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 721 CSSTLNRHKIIHTGE-------KPYKCKECGKAFNLSSTLTAHK--KIHTGE--KPYKCEE--CGKAFNQSSNLTTHKKI 787
Cdd:COG5048   266 PTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 788 HTSEKPYKC--EECGKSFNQFS------SLNIHKIIHT-------------------------------GEKPYKCGDYG 828
Cdd:COG5048   346 HTSISPAKEklLNSSSKFSPLLnneppqSLQQYKDLKNdkksetlsnscirnfkrdsnlslhiithlsfRPYNCKNPPCS 425

                         410       420
                  ....*....|....*....|....*
gi 1917203636 829 RAFNLSSNLTTHKKIHTGEKPYKCE 853
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAPLLCS 450
zf-H2C2_2 pfam13465
Zinc-finger double domain;
528-553 2.95e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 2.95e-04
                          10        20
                  ....*....|....*....|....*.
gi 1917203636 528 NLTEHKKIHTGEKPYKCEECGKAFNR 553
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
557-581 4.32e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 4.32e-04
                          10        20
                  ....*....|....*....|....*
gi 1917203636 557 LTKHKRIHTGEKPYKCEECGKAFNQ 581
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
221-245 4.32e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 4.32e-04
                          10        20
                  ....*....|....*....|....*
gi 1917203636 221 LTKHKRIHTGEKPYKCEECGKAFNQ 245
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
417-441 5.80e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 5.80e-04
                          10        20
                  ....*....|....*....|....*
gi 1917203636 417 LTRHKIIHTGEKPYKCKECGKAFNQ 441
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
725-748 6.79e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 6.79e-04
                          10        20
                  ....*....|....*....|....
gi 1917203636 725 LNRHKIIHTGEKPYKCKECGKAFN 748
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
501-525 6.86e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 6.86e-04
                          10        20
                  ....*....|....*....|....*
gi 1917203636 501 LTRHKKIHTGEKPYKCEECDRAFSQ 525
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
780-805 9.67e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 9.67e-04
                          10        20
                  ....*....|....*....|....*.
gi 1917203636 780 NLTTHKKIHTSEKPYKCEECGKSFNQ 805
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
696-721 1.04e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.04e-03
                          10        20
                  ....*....|....*....|....*.
gi 1917203636 696 NLTIHKRIHTGEKPYQCAECGKAFNC 721
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 426-506 1.74e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 1.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 426 GEKPYKCK--ECGKAFNQSSNLTEHKKiHTaeksykceECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSSTLTR 503
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYHML-HG--------HQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ...
gi 1917203636 504 HKK 506
Cdd:COG5189   417 HRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
753-777 2.04e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 2.04e-03
                          10        20
                  ....*....|....*....|....*
gi 1917203636 753 LTAHKKIHTGEKPYKCEECGKAFNQ 777
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
778-856 2.11e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.61  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 778 SSNLTTHKKIHTSEKPYKCEECGKSFNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLS--SNLTTHKKIHTGEKPYKCEYG 855
Cdd:COG5048    18 STPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKS 97


                  .
gi 1917203636 856 K 856
Cdd:COG5048    98 L 98
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 510-589 2.51e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 510 GEKPYKCE--ECDRAFSQSSNLTEHKKiHTGEKPYKCEECGKafnrfstlTKHKRIHTGEKPYKCEECGKAFNQSYQLTR 587
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYHML-HGHQNQKLHENPSP--------EKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ..
gi 1917203636 588 HK 589
Cdd:COG5189   417 HR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 762-813 2.62e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.62e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1917203636 762 GEKPYKCE--ECGKAFNQSSNLTTHKK-------------------IHTSEKPYKCEECGKSFNQFSSLNIHK 813
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYHMLhghqnqklhenpspekmniFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
176-340 2.73e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.22  E-value: 2.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 176 KHFKCKECSKSFCVLSQLTQHRR--IHTRVNSYKCEE----CGKAFNWFSTLTKHKRIHTGEKPYKCEecgkafnqssqL 249
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRsvNHSGESLKPFSCpyslCGKLFSRNDALKRHILLHTSISPAKEK-----------L 356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 250 TRHKIIHTEEKPNkceecgkafKQASHLTIHKIIHTGEKPYK-YEECGKVFSQSSHLTTQKILHTGEN--LYKCKECGKA 326
Cdd:COG5048   357 LNSSSKFSPLLNN---------EPPQSLQQYKDLKNDKKSETlSNSCIRNFKRDSNLSLHIITHLSFRpyNCKNPPCSKS 427

                         170
                  ....*....|....
gi 1917203636 327 FNLFSNLTNHKRIH 340
Cdd:COG5048   428 FNRHYNLIPHKKIH 441
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 482-561 2.73e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.24  E-value: 2.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1917203636 482 GEKPYKCE--ECGKAFNRSSTLTRHKKiHTGEKPYKCEECDRafsqssnlTEHKKIHTGEKPYKCEECGKAFNRFSTLTK 559
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYHML-HGHQNQKLHENPSP--------EKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ..
gi 1917203636 560 HK 561
Cdd:COG5189   417 HR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
444-469 5.18e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 5.18e-03
                          10        20
                  ....*....|....*....|....*.
gi 1917203636 444 NLTEHKKIHTAEKSYKCEECGKAFNQ 469
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
332-356 7.61e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 7.61e-03
                          10        20
                  ....*....|....*....|....*
gi 1917203636 332 NLTNHKRIHAGEKPYKCKECGRAFN 356
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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