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Conserved domains on  [gi|1879298395|ref|NP_001372618|]
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microtubule-associated protein 4 isoform 7 [Homo sapiens]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2099-2128 4.62e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 4.62e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298395 2099 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 2128
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2130-2159 7.38e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.35  E-value: 7.38e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298395 2130 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 2159
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 1815-2064 4.07e-11

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 69.20  E-value: 4.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1815 RPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 1894
Cdd:PHA03247  2684 RRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1895 AAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPS 1972
Cdd:PHA03247  2761 PTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1973 TLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTT 2046
Cdd:PHA03247  2841 PPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQ 2920

                          250
                   ....*....|....*...
gi 1879298395 2047 PFIDKKPTSAKPSSTTPR 2064
Cdd:PHA03247  2921 PQPPPPPQPQPPPPPPPR 2938
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2161-2191 1.38e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.03  E-value: 1.38e-08
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1879298395 2161 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 2191
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2076-2097 6.87e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.10  E-value: 6.87e-08
                           10        20
                   ....*....|....*....|..
gi 1879298395 2076 DLKNVRSKVGSTENIKHQPGGG 2097
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2099-2128 4.62e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 4.62e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298395 2099 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 2128
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2130-2159 7.38e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.35  E-value: 7.38e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298395 2130 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 2159
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1815-2064 4.07e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 69.20  E-value: 4.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1815 RPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 1894
Cdd:PHA03247  2684 RRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1895 AAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPS 1972
Cdd:PHA03247  2761 PTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1973 TLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTT 2046
Cdd:PHA03247  2841 PPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQ 2920

                          250
                   ....*....|....*...
gi 1879298395 2047 PFIDKKPTSAKPSSTTPR 2064
Cdd:PHA03247  2921 PQPPPPPQPQPPPPPPPR 2938
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2161-2191 1.38e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.03  E-value: 1.38e-08
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1879298395 2161 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 2191
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2076-2097 6.87e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.10  E-value: 6.87e-08
                           10        20
                   ....*....|....*....|..
gi 1879298395 2076 DLKNVRSKVGSTENIKHQPGGG 2097
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1816-2075 2.23e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 49.91  E-value: 2.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1816 PEEGRPVVSGTG--NDITTPPNKELPPSPEKKTKPLATTQP--AKTSTSKAKTQPTslPKQPAPT-------------TI 1878
Cdd:pfam05109  532 PNATSPTLGKTSptSAVTTPTPNATSPTPAVTTPTPNATIPtlGKTSPTSAVTTPT--PNATSPTvgetspqanttnhTL 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1879 GGLNKKPmslasglVPAAPPKRP--AVASARPSILPSK----DVKPKPIADAKAPEK--RASPSKPASAPASRSGSKSTQ 1950
Cdd:pfam05109  610 GGTSSTP-------VVTSPPKNAtsAVTTGQHNITSSStssmSLRPSSISETLSPSTsdNSTSHMPLLTSAHPTGGENIT 682

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1951 TVAKTTTAAAVASTG-PSSRSPSTLLPKKPTAIKTEGKPAEV--------KKMTAKSVPADLSRPKSTSTSSMKKTTTLS 2021
Cdd:pfam05109  683 QVTPASTSTHHVSTSsPAPRPGTTSQASGPGNSSTSTKPGEVnvtkgtppKNATSPQAPSGQKTAVPTVTSTGGKANSTT 762

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1879298395 2022 GTAPAAGVvPSRVKATPMPSR--PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 2075
Cdd:pfam05109  763 GGKHTTGH-GARTSTEPTTDYggDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPP 817
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2099-2128 4.62e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 4.62e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298395 2099 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 2128
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2130-2159 7.38e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.35  E-value: 7.38e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298395 2130 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 2159
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1815-2064 4.07e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 69.20  E-value: 4.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1815 RPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 1894
Cdd:PHA03247  2684 RRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1895 AAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPS 1972
Cdd:PHA03247  2761 PTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1973 TLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTT 2046
Cdd:PHA03247  2841 PPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQ 2920

                          250
                   ....*....|....*...
gi 1879298395 2047 PFIDKKPTSAKPSSTTPR 2064
Cdd:PHA03247  2921 PQPPPPPQPQPPPPPPPR 2938
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1783-2071 1.33e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.19  E-value: 1.33e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1783 RPTKSRGLTPLlPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKA 1862
Cdd:PHA03247  2711 APHALVSATPL-PPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVA 2789

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1863 KTQPTS----LPKQPAPTTIGGLNKKPmSLASGLVPAAP-PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPA 1937
Cdd:PHA03247  2790 SLSESReslpSPWDPADPPAAVLAPAA-ALPPAASPAGPlPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPS 2868

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1938 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADlsRPKSTSTSSMKKT 2017
Cdd:PHA03247  2869 RSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP--PPPPRPQPPLAPT 2946

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1879298395 2018 TTLSGTAPAAG---------VVPSRVKAT------PMPSRPSTTPfidkkPTSAKPSSTTPRLSRLATN 2071
Cdd:PHA03247  2947 TDPAGAGEPSGavpqpwlgaLVPGRVAVPrfrvpqPAPSREAPAS-----STPPLTGHSLSRVSSWASS 3010
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2161-2191 1.38e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.03  E-value: 1.38e-08
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1879298395 2161 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 2191
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2076-2097 6.87e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.10  E-value: 6.87e-08
                           10        20
                   ....*....|....*....|..
gi 1879298395 2076 DLKNVRSKVGSTENIKHQPGGG 2097
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1814-2075 3.03e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.10  E-value: 3.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1814 ARPEEGRPVVSG--TGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGG---LNKKPMSL 1888
Cdd:PHA03247  2591 APPQSARPRAPVddRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGrvsRPRRARRL 2670

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1889 ASGLVPAAPPKRPAVASARPSILPSKDVkpkpiadakapekrASPSKPASAPASRsgskstqtvaktttaaavastgPSS 1968
Cdd:PHA03247  2671 GRAAQASSPPQRPRRRAARPTVGSLTSL--------------ADPPPPPPTPEPA----------------------PHA 2714

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1969 RSPSTLLPKKPTAIK-----TEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTT----------LSGTAPAAGVVPSR 2033
Cdd:PHA03247  2715 LVSATPLPPGPAAARqaspaLPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAppaapaagppRRLTRPAVASLSES 2794

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1879298395 2034 VKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 2075
Cdd:PHA03247  2795 RESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1820-2069 4.85e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.71  E-value: 4.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1820 RPVVSGTGNDITTPPnkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQP----APTTIGGLN---------KKPM 1886
Cdd:PHA03247  2634 AANEPDPHPPPTVPP----PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPrrraARPTVGSLTsladpppppPTPE 2709

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1887 SLASGLVPAAPPkrPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASaPASRSGSKSTQTVAKTTTAAAVASTGP 1966
Cdd:PHA03247  2710 PAPHALVSATPL--PPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPAR-PPTTAGPPAPAPPAAPAAGPPRRLTRP 2786

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1967 SSRSPSTLLPKKPTAIKTEGKPAEVkkmtakSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTT 2046
Cdd:PHA03247  2787 AVASLSESRESLPSPWDPADPPAAV------LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG 2860

                          250       260
                   ....*....|....*....|....*..
gi 1879298395 2047 PFIDKKPTSAKP----SSTTPRLSRLA 2069
Cdd:PHA03247  2861 DVRRRPPSRSPAakpaAPARPPVRRLA 2887
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 1752-2073 5.33e-07

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 55.08  E-value: 5.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1752 QKMTEKSESKTPGEgKKEDKSRMAEPMKGymrpTKSRGLTPLLPKSTIQEQERHKQLKSAGIARpEEGRPVVSGTGNDIT 1831
Cdd:PTZ00449   486 KKLIKKSKKKLAPI-EEEDSDKHDEPPEG----PEASGLPPKAPGDKEGEEGEHEDSKESDEPK-EGGKPGETKEGEVGK 559

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1832 TP-PNKELPPS--------PEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPttigglnKKPMSLAsglVPAAPPKRPA 1902
Cdd:PTZ00449   560 KPgPAKEHKPSkiptlskkPEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSP-------KLPELLD---IPKSPKRPES 629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1903 VASARPSILPSKDVKPKPIADAKAPEKRASPSKPA---------------SAPASRSGSKSTQTVAKTTTAAAVASTGPS 1967
Cdd:PTZ00449   630 PKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKppfdpkfkekfyddyLDAAAKSKETKTTVVLDESFESILKETLPE 709

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1968 S-----RSPSTLLPKKPTAIKTEGKPaeVKKMTAKSV-PADLSRPKSTSTSSMKKTttlSGTAPAAGVVPSRVKA----- 2036
Cdd:PTZ00449   710 TpgtpfTTPRPLPPKLPRDEEFPFEP--IGDPDAEQPdDIEFFTPPEEERTFFHET---PADTPLPDILAEEFKEediha 784

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1879298395 2037 -TPMPSRPSTTPfidKKPT--SAKPSSTTP-------RLSRLATNTS 2073
Cdd:PTZ00449   785 eTGEPDEAMKRP---DSPSehEDKPPGDHPslpkkrhRLDGLALSTT 828
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1762-2082 2.53e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 2.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1762 TPGEGKKEDKSRMAEPMKGYMRPTksrgltpLLPKSTIQEQERHKQLksAGIARPEEgrpVVSGTGNDITTP-PNKELPP 1840
Cdd:PHA03247  2495 APDPGGGGPPDPDAPPAPSRLAPA-------ILPDEPVGEPVHPRML--TWIRGLEE---LASDDAGDPPPPlPPAAPPA 2562

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1841 SPEKKT-KPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLA--SGLVPAAPPKRPAVASARPSilPSKDVK 1917
Cdd:PHA03247  2563 APDRSVpPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAppSPLPPDTHAPDPPPPSPSPA--ANEPDP 2640

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1918 PKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTegkPAEVKKMTAK 1997
Cdd:PHA03247  2641 HPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPT---PEPAPHALVS 2717

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1998 SVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVkaTPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDL 2077
Cdd:PHA03247  2718 ATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGP--ARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESR 2795


                   ....*
gi 1879298395 2078 KNVRS 2082
Cdd:PHA03247  2796 ESLPS 2800
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1811-2088 3.78e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 52.48  E-value: 3.78e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1811 AGIARPEEGRPVVSGTGNDITTPPNKELPPSP---EKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPms 1887
Cdd:PHA03307    44 VSDSAELAAVTVVAGAAACDRFEPPTGPPPGPgteAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTP-- 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1888 lasglVPAAPPkrPAVASARPSILPSKDvKPKPIADAKAPEKRASPSKPASAPASRSGskSTQTVAKTTTAAAVASTGPS 1967
Cdd:PHA03307   122 -----PPASPP--PSPAPDLSEMLRPVG-SPGPPPAASPPAAGASPAAVASDAASSRQ--AALPLSSPEETARAPSSPPA 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1968 SRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA-----------PAAGVVPSRVKA 2036
Cdd:PHA03307   192 EPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGwgpenecplprPAPITLPTRIWE 271

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1879298395 2037 TPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 2088
Cdd:PHA03307   272 ASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRE 323
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1706-2088 1.42e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.55  E-value: 1.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1706 TPEIQSDFLHS---KVEAPPSEVADTLVIMTASKGVRLPEPKDKilETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYM 1782
Cdd:PHA03307    27 TPGDAADDLLSgsqGQLVSDSAELAAVTVVAGAAACDRFEPPTG--PPPGPGTEAPANESRSTPTWSLSTLAPASPAREG 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1783 RPTKSRGLTPLLPKSTIQEQErhkQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTK--------PLATTQP 1854
Cdd:PHA03307   105 SPTPPGPSSPDPPPPTPPPAS---PPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAassrqaalPLSSPEE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1855 AKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAV--ASARPSILPSKDVKPKPIADAKAPEKRAS 1932
Cdd:PHA03307   182 TARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADdaGASSSDSSSSESSGCGWGPENECPLPRPA 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1933 PSKPASAPASRSGSKSTQTVAKTTTAaavaSTGPSSRSPSTLlPKKPTAIKTEGKPAEVKKMTAKSvPADLSRPKSTSTS 2012
Cdd:PHA03307   262 PITLPTRIWEASGWNGPSSRPGPASS----SSSPRERSPSPS-PSSPGSGPAPSSPRASSSSSSSR-ESSSSSTSSSSES 335

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1879298395 2013 SMKKTTTlSGTAPAAGVVPSRVKATPMPSRPSTTPfiDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 2088
Cdd:PHA03307   336 SRGAAVS-PGPSPSRSPSPSRPPPPADPSSPRKRP--RPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFP 408
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1816-2075 2.23e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 49.91  E-value: 2.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1816 PEEGRPVVSGTG--NDITTPPNKELPPSPEKKTKPLATTQP--AKTSTSKAKTQPTslPKQPAPT-------------TI 1878
Cdd:pfam05109  532 PNATSPTLGKTSptSAVTTPTPNATSPTPAVTTPTPNATIPtlGKTSPTSAVTTPT--PNATSPTvgetspqanttnhTL 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1879 GGLNKKPmslasglVPAAPPKRP--AVASARPSILPSK----DVKPKPIADAKAPEK--RASPSKPASAPASRSGSKSTQ 1950
Cdd:pfam05109  610 GGTSSTP-------VVTSPPKNAtsAVTTGQHNITSSStssmSLRPSSISETLSPSTsdNSTSHMPLLTSAHPTGGENIT 682

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1951 TVAKTTTAAAVASTG-PSSRSPSTLLPKKPTAIKTEGKPAEV--------KKMTAKSVPADLSRPKSTSTSSMKKTTTLS 2021
Cdd:pfam05109  683 QVTPASTSTHHVSTSsPAPRPGTTSQASGPGNSSTSTKPGEVnvtkgtppKNATSPQAPSGQKTAVPTVTSTGGKANSTT 762

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1879298395 2022 GTAPAAGVvPSRVKATPMPSR--PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 2075
Cdd:pfam05109  763 GGKHTTGH-GARTSTEPTTDYggDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPP 817
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1872-2063 2.40e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 49.85  E-value: 2.40e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1872 QPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASAR-------PSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRS 1944
Cdd:PRK07003   359 EPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASavpavtaVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADR 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1945 GSKSTQtvaktttaaavastgpssrSPSTLLPKKPTAIKTEGKPAEvkkmtAKSVPADLSRPKSTSTSSMKKTTTLSGTA 2024
Cdd:PRK07003   439 GDDAAD-------------------GDAPVPAKANARASADSRCDE-----RDAQPPADSGSASAPASDAPPDAAFEPAP 494

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1879298395 2025 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP 2063
Cdd:PRK07003   495 RAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEAR 533
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1831-2097 5.18e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 48.76  E-value: 5.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1831 TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIgglNKKPMSLASGLVPAAPPKrpAVASARPSI 1910
Cdd:pfam05109  481 TTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVT---TPTPNATSPTLGKTSPTS--AVTTPTPNA 555

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1911 LPSKDVKPKPIADAKAPE-KRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK-- 1987
Cdd:pfam05109  556 TSPTPAVTTPTPNATIPTlGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQhn 635

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1988 --PAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG-----VVPSRVK------ATPMPsRPSTTPFID---K 2051
Cdd:pfam05109  636 itSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGenitqVTPASTSthhvstSSPAP-RPGTTSQASgpgN 714

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1879298395 2052 KPTSAKP------------SSTTPRLSRlATNTSAPDLKNVRSKVGSTENIKHQPGGG 2097
Cdd:pfam05109  715 SSTSTKPgevnvtkgtppkNATSPQAPS-GQKTAVPTVTSTGGKANSTTGGKHTTGHG 771
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1810-2075 3.42e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.00  E-value: 3.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1810 SAGIARPEEGRPVVSGT--GNDITTPPNKELPPSPEKKTKPLATTQPA--KTSTSKAKTQPTSLPKQPAPTTIGGLNKKP 1885
Cdd:PRK07003   363 TGGGAPGGGVPARVAGAvpAPGARAAAAVGASAVPAVTAVTGAAGAALapKAAAAAAATRAEAPPAAPAPPATADRGDDA 442

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1886 MSlasglVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG 1965
Cdd:PRK07003   443 AD-----GDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1966 PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 2045
Cdd:PRK07003   518 REDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVP 597

                          250       260       270
                   ....*....|....*....|....*....|
gi 1879298395 2046 TPFIDKKPTSAKPSSTTPRLSRLATNTSAP 2075
Cdd:PRK07003   598 TPRARAATGDAPPNGAARAEQAAESRGAPP 627
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1792-2040 3.70e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 3.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1792 PLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPS--PEKKTKPLATTQPAKTSTSKAKTQPtSL 1869
Cdd:PHA03247  2772 PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAasPAGPLPPPTSAQPTAPPPPPGPPPP-SL 2850

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1870 PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDV------------KPKPIADAKAPEKRASPSKPA 1937
Cdd:PHA03247  2851 PLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESfalppdqperppQPQAPPPPQPQPQPPPPPQPQ 2930

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1938 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPkkptaikteGKPAEVKKMTAKSVPadlSRPKSTSTSSMKKT 2017
Cdd:PHA03247  2931 PPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP---------GRVAVPRFRVPQPAP---SREAPASSTPPLTG 2998

                          250       260
                   ....*....|....*....|...
gi 1879298395 2018 TTLSGTAPAAGVVPSRVKATPMP 2040
Cdd:PHA03247  2999 HSLSRVSSWASSLALHEETDPPP 3021
PHA03378 PHA03378
EBNA-3B; Provisional
 1817-2063 2.35e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 43.13  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1817 EEGRPVVSGTGNDITTPPNK----ELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGL 1892
Cdd:PHA03378   549 ESDEPASTEPVHDQLLPAPGlgplQIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPL 628

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1893 VP-AAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASapasrsgskstqtvaktttaaavastgPSSRSP 1971
Cdd:PHA03378   629 RPiPMRPLRMQPITFNVLVFPTPHQPPQVEITPYKPTWTQIGHIPYQ---------------------------PSPTGA 681

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1972 STLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK---ATPMPSRPSTTPF 2048
Cdd:PHA03378   682 NTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARppaAAPGRARPPAAAP 761

                          250
                   ....*....|....*
gi 1879298395 2049 IDKKPTSAKPSSTTP 2063
Cdd:PHA03378   762 GRARPPAAAPGAPTP 776
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 1851-2079 3.64e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 42.61  E-value: 3.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1851 TTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPmslasglVPAAPPKRPAVASARPSILPsKDVKPKPIADAKAPEKR 1930
Cdd:PLN03209   309 TTAPLTPMEELLAKIPSQRVPPKESDAADGPKPVP-------TKPVTPEAPSPPIEEEPPQP-KAVVPRPLSPYTAYEDL 380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1931 ASPSKPAsaPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPtaiktegKPAEVKK---MTAKSVPADLSRPK 2007
Cdd:PLN03209   381 KPPTSPI--PTPPSSSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEP-------AQVEAKKtrpLSPYARYEDLKPPT 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 2008 S----------TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFID--KKPTSAKPSSTTPRLSRLATNTSAP 2075
Cdd:PLN03209   452 SpsptaptgvsPSVSSTSSVPAVPDTAPATAATDAAAPPPANMRPLSPYAVYDdlKPPTSPSPAAPVGKVAPSSTNEVVK 531


                   ....
gi 1879298395 2076 DLKN 2079
Cdd:PLN03209   532 VGNS 535
PRK13808 PRK13808
adenylate kinase; Provisional
 1846-1987 5.10e-03

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 41.41  E-value: 5.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1846 TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTtigglnKKPMSLASGLVPAAPPKRPAVASARPsilPSKDVKPKPIADAK 1925
Cdd:PRK13808   199 AKKAAKTPAAKSGAKKASAKAKSAAKKVSKK------KAAKTAVSAKKAAKTAAKAAKKAKKT---AKKALKKAAKAVKK 269

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1879298395 1926 APEKraspSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 1987
Cdd:PRK13808   270 AAKK----AAKAAAKAAKGAAKATKGKAKAKKKAGKKAAAGSKAKATAKAPKRGAKGKKAKK 327
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 1836-2059 9.52e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 41.07  E-value: 9.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1836 KELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL------------PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAV 1903
Cdd:PLN03209   337 DGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPlspytayedlkpPTSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSP 416

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298395 1904 ASarPSILPSKDVKPKPIADAK--APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTA 1981
Cdd:PLN03209   417 GS--ASNVPEVEPAQVEAKKTRplSPYARYEDLKPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPPPANM 494

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1879298395 1982 IKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSR-VKATPMPSRPSTTPFIDKKPTSAKPS 2059
Cdd:PLN03209   495 RPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHhAQPKPRPLSPYTMYEDLKPPTSPTPS 573
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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