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Conserved domains on  [gi|1879298482|ref|NP_001372593|]
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microtubule-associated protein 4 isoform 9 [Homo sapiens]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2059-2088 4.58e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 4.58e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298482 2059 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 2088
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2090-2119 7.32e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.35  E-value: 7.32e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298482 2090 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 2119
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 1775-2024 3.52e-11

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 69.20  E-value: 3.52e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1775 RPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 1854
Cdd:PHA03247  2684 RRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1855 AAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPS 1932
Cdd:PHA03247  2761 PTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1933 TLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTT 2006
Cdd:PHA03247  2841 PPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQ 2920

                          250
                   ....*....|....*...
gi 1879298482 2007 PFIDKKPTSAKPSSTTPR 2024
Cdd:PHA03247  2921 PQPPPPPQPQPPPPPPPR 2938
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2121-2151 1.37e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.03  E-value: 1.37e-08
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1879298482 2121 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 2151
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2036-2057 6.82e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.10  E-value: 6.82e-08
                           10        20
                   ....*....|....*....|..
gi 1879298482 2036 DLKNVRSKVGSTENIKHQPGGG 2057
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2059-2088 4.58e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 4.58e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298482 2059 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 2088
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2090-2119 7.32e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.35  E-value: 7.32e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298482 2090 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 2119
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1775-2024 3.52e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 69.20  E-value: 3.52e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1775 RPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 1854
Cdd:PHA03247  2684 RRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1855 AAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPS 1932
Cdd:PHA03247  2761 PTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1933 TLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTT 2006
Cdd:PHA03247  2841 PPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQ 2920

                          250
                   ....*....|....*...
gi 1879298482 2007 PFIDKKPTSAKPSSTTPR 2024
Cdd:PHA03247  2921 PQPPPPPQPQPPPPPPPR 2938
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2121-2151 1.37e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.03  E-value: 1.37e-08
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1879298482 2121 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 2151
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2036-2057 6.82e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.10  E-value: 6.82e-08
                           10        20
                   ....*....|....*....|..
gi 1879298482 2036 DLKNVRSKVGSTENIKHQPGGG 2057
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1776-2035 2.04e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 49.91  E-value: 2.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1776 PEEGRPVVSGTG--NDITTPPNKELPPSPEKKTKPLATTQP--AKTSTSKAKTQPTslPKQPAPT-------------TI 1838
Cdd:pfam05109  532 PNATSPTLGKTSptSAVTTPTPNATSPTPAVTTPTPNATIPtlGKTSPTSAVTTPT--PNATSPTvgetspqanttnhTL 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1839 GGLNKKPmslasglVPAAPPKRP--AVASARPSILPSK----DVKPKPIADAKAPEK--RASPSKPASAPASRSGSKSTQ 1910
Cdd:pfam05109  610 GGTSSTP-------VVTSPPKNAtsAVTTGQHNITSSStssmSLRPSSISETLSPSTsdNSTSHMPLLTSAHPTGGENIT 682

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1911 TVAKTTTAAAVASTG-PSSRSPSTLLPKKPTAIKTEGKPAEV--------KKMTAKSVPADLSRPKSTSTSSMKKTTTLS 1981
Cdd:pfam05109  683 QVTPASTSTHHVSTSsPAPRPGTTSQASGPGNSSTSTKPGEVnvtkgtppKNATSPQAPSGQKTAVPTVTSTGGKANSTT 762

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1879298482 1982 GTAPAAGVvPSRVKATPMPSR--PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 2035
Cdd:pfam05109  763 GGKHTTGH-GARTSTEPTTDYggDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPP 817
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2059-2088 4.58e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 4.58e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298482 2059 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 2088
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2090-2119 7.32e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.35  E-value: 7.32e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1879298482 2090 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 2119
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1775-2024 3.52e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 69.20  E-value: 3.52e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1775 RPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 1854
Cdd:PHA03247  2684 RRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1855 AAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPS 1932
Cdd:PHA03247  2761 PTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1933 TLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTT 2006
Cdd:PHA03247  2841 PPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQ 2920

                          250
                   ....*....|....*...
gi 1879298482 2007 PFIDKKPTSAKPSSTTPR 2024
Cdd:PHA03247  2921 PQPPPPPQPQPPPPPPPR 2938
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1743-2031 9.86e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.57  E-value: 9.86e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1743 RPTKSRGLTPLlPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKA 1822
Cdd:PHA03247  2711 APHALVSATPL-PPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVA 2789

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1823 KTQPTS----LPKQPAPTTIGGLNKKPmSLASGLVPAAP-PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPA 1897
Cdd:PHA03247  2790 SLSESReslpSPWDPADPPAAVLAPAA-ALPPAASPAGPlPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPS 2868

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1898 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADlsRPKSTSTSSMKKT 1977
Cdd:PHA03247  2869 RSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP--PPPPRPQPPLAPT 2946

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1879298482 1978 TTLSGTAPAAG---------VVPSRVKAT------PMPSRPSTTPfidkkPTSAKPSSTTPRLSRLATN 2031
Cdd:PHA03247  2947 TDPAGAGEPSGavpqpwlgaLVPGRVAVPrfrvpqPAPSREAPAS-----STPPLTGHSLSRVSSWASS 3010
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2121-2151 1.37e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.03  E-value: 1.37e-08
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1879298482 2121 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 2151
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2036-2057 6.82e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.10  E-value: 6.82e-08
                           10        20
                   ....*....|....*....|..
gi 1879298482 2036 DLKNVRSKVGSTENIKHQPGGG 2057
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1774-2035 2.47e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.49  E-value: 2.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1774 ARPEEGRPVVSG--TGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGG---LNKKPMSL 1848
Cdd:PHA03247  2591 APPQSARPRAPVddRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGrvsRPRRARRL 2670

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1849 ASGLVPAAPPKRPAVASARPSILPSKDVkpkpiadakapekrASPSKPASAPASRsgskstqtvaktttaaavastgPSS 1928
Cdd:PHA03247  2671 GRAAQASSPPQRPRRRAARPTVGSLTSL--------------ADPPPPPPTPEPA----------------------PHA 2714

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1929 RSPSTLLPKKPTAIK-----TEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTT----------LSGTAPAAGVVPSR 1993
Cdd:PHA03247  2715 LVSATPLPPGPAAARqaspaLPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAppaapaagppRRLTRPAVASLSES 2794

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 1879298482 1994 VKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 2035
Cdd:PHA03247  2795 RESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1780-2029 3.85e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.10  E-value: 3.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1780 RPVVSGTGNDITTPPnkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQP----APTTIGGLN---------KKPM 1846
Cdd:PHA03247  2634 AANEPDPHPPPTVPP----PERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPrrraARPTVGSLTsladpppppPTPE 2709

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1847 SLASGLVPAAPPkrPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASaPASRSGSKSTQTVAKTTTAAAVASTGP 1926
Cdd:PHA03247  2710 PAPHALVSATPL--PPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPAR-PPTTAGPPAPAPPAAPAAGPPRRLTRP 2786

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1927 SSRSPSTLLPKKPTAIKTEGKPAEVkkmtakSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTT 2006
Cdd:PHA03247  2787 AVASLSESRESLPSPWDPADPPAAV------LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGG 2860

                          250       260
                   ....*....|....*....|....*..
gi 1879298482 2007 PFIDKKPTSAKP----SSTTPRLSRLA 2029
Cdd:PHA03247  2861 DVRRRPPSRSPAakpaAPARPPVRRLA 2887
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 1712-2033 5.14e-07

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 55.08  E-value: 5.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1712 QKMTEKSESKTPGEgKKEDKSRMAEPMKGymrpTKSRGLTPLLPKSTIQEQERHKQLKSAGIARpEEGRPVVSGTGNDIT 1791
Cdd:PTZ00449   486 KKLIKKSKKKLAPI-EEEDSDKHDEPPEG----PEASGLPPKAPGDKEGEEGEHEDSKESDEPK-EGGKPGETKEGEVGK 559

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1792 TP-PNKELPPS--------PEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPttigglnKKPMSLAsglVPAAPPKRPA 1862
Cdd:PTZ00449   560 KPgPAKEHKPSkiptlskkPEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSP-------KLPELLD---IPKSPKRPES 629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1863 VASARPSILPSKDVKPKPIADAKAPEKRASPSKPA---------------SAPASRSGSKSTQTVAKTTTAAAVASTGPS 1927
Cdd:PTZ00449   630 PKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKppfdpkfkekfyddyLDAAAKSKETKTTVVLDESFESILKETLPE 709

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1928 S-----RSPSTLLPKKPTAIKTEGKPaeVKKMTAKSV-PADLSRPKSTSTSSMKKTttlSGTAPAAGVVPSRVKA----- 1996
Cdd:PTZ00449   710 TpgtpfTTPRPLPPKLPRDEEFPFEP--IGDPDAEQPdDIEFFTPPEEERTFFHET---PADTPLPDILAEEFKEediha 784

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 1879298482 1997 -TPMPSRPSTTPfidKKPT--SAKPSSTTP-------RLSRLATNTS 2033
Cdd:PTZ00449   785 eTGEPDEAMKRP---DSPSehEDKPPGDHPslpkkrhRLDGLALSTT 828
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1722-2042 2.00e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 2.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1722 TPGEGKKEDKSRMAEPMKGYMRPTksrgltpLLPKSTIQEQERHKQLksAGIARPEEgrpVVSGTGNDITTP-PNKELPP 1800
Cdd:PHA03247  2495 APDPGGGGPPDPDAPPAPSRLAPA-------ILPDEPVGEPVHPRML--TWIRGLEE---LASDDAGDPPPPlPPAAPPA 2562

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1801 SPEKKT-KPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLA--SGLVPAAPPKRPAVASARPSilPSKDVK 1877
Cdd:PHA03247  2563 APDRSVpPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAppSPLPPDTHAPDPPPPSPSPA--ANEPDP 2640

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1878 PKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTegkPAEVKKMTAK 1957
Cdd:PHA03247  2641 HPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPT---PEPAPHALVS 2717

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1958 SVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVkaTPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDL 2037
Cdd:PHA03247  2718 ATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGP--ARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESR 2795


                   ....*
gi 1879298482 2038 KNVRS 2042
Cdd:PHA03247  2796 ESLPS 2800
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1771-2048 3.05e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 52.87  E-value: 3.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1771 AGIARPEEGRPVVSGTGNDITTPPNKELPPSP---EKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPms 1847
Cdd:PHA03307    44 VSDSAELAAVTVVAGAAACDRFEPPTGPPPGPgteAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTP-- 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1848 lasglVPAAPPkrPAVASARPSILPSKDvKPKPIADAKAPEKRASPSKPASAPASRSGskSTQTVAKTTTAAAVASTGPS 1927
Cdd:PHA03307   122 -----PPASPP--PSPAPDLSEMLRPVG-SPGPPPAASPPAAGASPAAVASDAASSRQ--AALPLSSPEETARAPSSPPA 191

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1928 SRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTA-----------PAAGVVPSRVKA 1996
Cdd:PHA03307   192 EPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGwgpenecplprPAPITLPTRIWE 271

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1879298482 1997 TPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 2048
Cdd:PHA03307   272 ASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRE 323
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1666-2048 1.04e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.94  E-value: 1.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1666 TPEIQSDFLHS---KVEAPPSEVADTLVIMTASKGVRLPEPKDKilETPQKMTEKSESKTPGEGKKEDKSRMAEPMKGYM 1742
Cdd:PHA03307    27 TPGDAADDLLSgsqGQLVSDSAELAAVTVVAGAAACDRFEPPTG--PPPGPGTEAPANESRSTPTWSLSTLAPASPAREG 104

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1743 RPTKSRGLTPLLPKSTIQEQErhkQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTK--------PLATTQP 1814
Cdd:PHA03307   105 SPTPPGPSSPDPPPPTPPPAS---PPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAassrqaalPLSSPEE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1815 AKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAV--ASARPSILPSKDVKPKPIADAKAPEKRAS 1892
Cdd:PHA03307   182 TARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADdaGASSSDSSSSESSGCGWGPENECPLPRPA 261

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1893 PSKPASAPASRSGSKSTQTVAKTTTAaavaSTGPSSRSPSTLlPKKPTAIKTEGKPAEVKKMTAKSvPADLSRPKSTSTS 1972
Cdd:PHA03307   262 PITLPTRIWEASGWNGPSSRPGPASS----SSSPRERSPSPS-PSSPGSGPAPSSPRASSSSSSSR-ESSSSSTSSSSES 335

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1879298482 1973 SMKKTTTlSGTAPAAGVVPSRVKATPMPSRPSTTPfiDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 2048
Cdd:PHA03307   336 SRGAAVS-PGPSPSRSPSPSRPPPPADPSSPRKRP--RPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFP 408
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1776-2035 2.04e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 49.91  E-value: 2.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1776 PEEGRPVVSGTG--NDITTPPNKELPPSPEKKTKPLATTQP--AKTSTSKAKTQPTslPKQPAPT-------------TI 1838
Cdd:pfam05109  532 PNATSPTLGKTSptSAVTTPTPNATSPTPAVTTPTPNATIPtlGKTSPTSAVTTPT--PNATSPTvgetspqanttnhTL 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1839 GGLNKKPmslasglVPAAPPKRP--AVASARPSILPSK----DVKPKPIADAKAPEK--RASPSKPASAPASRSGSKSTQ 1910
Cdd:pfam05109  610 GGTSSTP-------VVTSPPKNAtsAVTTGQHNITSSStssmSLRPSSISETLSPSTsdNSTSHMPLLTSAHPTGGENIT 682

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1911 TVAKTTTAAAVASTG-PSSRSPSTLLPKKPTAIKTEGKPAEV--------KKMTAKSVPADLSRPKSTSTSSMKKTTTLS 1981
Cdd:pfam05109  683 QVTPASTSTHHVSTSsPAPRPGTTSQASGPGNSSTSTKPGEVnvtkgtppKNATSPQAPSGQKTAVPTVTSTGGKANSTT 762

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1879298482 1982 GTAPAAGVvPSRVKATPMPSR--PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 2035
Cdd:pfam05109  763 GGKHTTGH-GARTSTEPTTDYggDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPP 817
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1832-2023 2.12e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 49.85  E-value: 2.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1832 QPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASAR-------PSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRS 1904
Cdd:PRK07003   359 EPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASavpavtaVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADR 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1905 GSKSTQtvaktttaaavastgpssrSPSTLLPKKPTAIKTEGKPAEvkkmtAKSVPADLSRPKSTSTSSMKKTTTLSGTA 1984
Cdd:PRK07003   439 GDDAAD-------------------GDAPVPAKANARASADSRCDE-----RDAQPPADSGSASAPASDAPPDAAFEPAP 494

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1879298482 1985 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP 2023
Cdd:PRK07003   495 RAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEAR 533
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1791-2057 4.52e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 48.76  E-value: 4.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1791 TTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIgglNKKPMSLASGLVPAAPPKrpAVASARPSI 1870
Cdd:pfam05109  481 TTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVT---TPTPNATSPTLGKTSPTS--AVTTPTPNA 555

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1871 LPSKDVKPKPIADAKAPE-KRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK-- 1947
Cdd:pfam05109  556 TSPTPAVTTPTPNATIPTlGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQhn 635

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1948 --PAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG-----VVPSRVK------ATPMPsRPSTTPFID---K 2011
Cdd:pfam05109  636 itSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGenitqVTPASTSthhvstSSPAP-RPGTTSQASgpgN 714

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1879298482 2012 KPTSAKP------------SSTTPRLSRlATNTSAPDLKNVRSKVGSTENIKHQPGGG 2057
Cdd:pfam05109  715 SSTSTKPgevnvtkgtppkNATSPQAPS-GQKTAVPTVTSTGGKANSTTGGKHTTGHG 771
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
1770-2035 3.03e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.00  E-value: 3.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1770 SAGIARPEEGRPVVSGT--GNDITTPPNKELPPSPEKKTKPLATTQPA--KTSTSKAKTQPTSLPKQPAPTTIGGLNKKP 1845
Cdd:PRK07003   363 TGGGAPGGGVPARVAGAvpAPGARAAAAVGASAVPAVTAVTGAAGAALapKAAAAAAATRAEAPPAAPAPPATADRGDDA 442

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1846 MSlasglVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG 1925
Cdd:PRK07003   443 AD-----GDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1926 PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 2005
Cdd:PRK07003   518 REDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVP 597

                          250       260       270
                   ....*....|....*....|....*....|
gi 1879298482 2006 TPFIDKKPTSAKPSSTTPRLSRLATNTSAP 2035
Cdd:PRK07003   598 TPRARAATGDAPPNGAARAEQAAESRGAPP 627
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1752-2000 3.37e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.08  E-value: 3.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1752 PLLPKSTIQEQERHKQLKSAGIARPEEGRPVVSGTGNDITTPPNKELPPS--PEKKTKPLATTQPAKTSTSKAKTQPtSL 1829
Cdd:PHA03247  2772 PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAasPAGPLPPPTSAQPTAPPPPPGPPPP-SL 2850

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1830 PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDV------------KPKPIADAKAPEKRASPSKPA 1897
Cdd:PHA03247  2851 PLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESfalppdqperppQPQAPPPPQPQPQPPPPPQPQ 2930

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1898 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPkkptaikteGKPAEVKKMTAKSVPadlSRPKSTSTSSMKKT 1977
Cdd:PHA03247  2931 PPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP---------GRVAVPRFRVPQPAP---SREAPASSTPPLTG 2998

                          250       260
                   ....*....|....*....|...
gi 1879298482 1978 TTLSGTAPAAGVVPSRVKATPMP 2000
Cdd:PHA03247  2999 HSLSRVSSWASSLALHEETDPPP 3021
PHA03378 PHA03378
EBNA-3B; Provisional
 1777-2023 2.21e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 43.13  E-value: 2.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1777 EEGRPVVSGTGNDITTPPNK----ELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGL 1852
Cdd:PHA03378   549 ESDEPASTEPVHDQLLPAPGlgplQIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEPPTTQSHIPETSAPRQWPMPL 628

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1853 VP-AAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASapasrsgskstqtvaktttaaavastgPSSRSP 1931
Cdd:PHA03378   629 RPiPMRPLRMQPITFNVLVFPTPHQPPQVEITPYKPTWTQIGHIPYQ---------------------------PSPTGA 681

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1932 STLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK---ATPMPSRPSTTPF 2008
Cdd:PHA03378   682 NTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARppaAAPGRARPPAAAP 761

                          250
                   ....*....|....*
gi 1879298482 2009 IDKKPTSAKPSSTTP 2023
Cdd:PHA03378   762 GRARPPAAAPGAPTP 776
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 1811-2039 3.31e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 42.61  E-value: 3.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1811 TTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPmslasglVPAAPPKRPAVASARPSILPsKDVKPKPIADAKAPEKR 1890
Cdd:PLN03209   309 TTAPLTPMEELLAKIPSQRVPPKESDAADGPKPVP-------TKPVTPEAPSPPIEEEPPQP-KAVVPRPLSPYTAYEDL 380

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1891 ASPSKPAsaPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPtaiktegKPAEVKK---MTAKSVPADLSRPK 1967
Cdd:PLN03209   381 KPPTSPI--PTPPSSSPASSKSVDAVAKPAEPDVVPSPGSASNVPEVEP-------AQVEAKKtrpLSPYARYEDLKPPT 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1968 S----------TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFID--KKPTSAKPSSTTPRLSRLATNTSAP 2035
Cdd:PLN03209   452 SpsptaptgvsPSVSSTSSVPAVPDTAPATAATDAAAPPPANMRPLSPYAVYDdlKPPTSPSPAAPVGKVAPSSTNEVVK 531


                   ....
gi 1879298482 2036 DLKN 2039
Cdd:PLN03209   532 VGNS 535
PRK13808 PRK13808
adenylate kinase; Provisional
 1806-1947 5.66e-03

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 41.41  E-value: 5.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1806 TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTtigglnKKPMSLASGLVPAAPPKRPAVASARPsilPSKDVKPKPIADAK 1885
Cdd:PRK13808   199 AKKAAKTPAAKSGAKKASAKAKSAAKKVSKK------KAAKTAVSAKKAAKTAAKAAKKAKKT---AKKALKKAAKAVKK 269

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1879298482 1886 APEKraspSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 1947
Cdd:PRK13808   270 AAKK----AAKAAAKAAKGAAKATKGKAKAKKKAGKKAAAGSKAKATAKAPKRGAKGKKAKK 327
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 1796-2019 9.10e-03

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 41.07  E-value: 9.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1796 KELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL------------PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAV 1863
Cdd:PLN03209   337 DGPKPVPTKPVTPEAPSPPIEEEPPQPKAVVPRPlspytayedlkpPTSPIPTPPSSSPASSKSVDAVAKPAEPDVVPSP 416

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1864 ASarPSILPSKDVKPKPIADAK--APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTA 1941
Cdd:PLN03209   417 GS--ASNVPEVEPAQVEAKKTRplSPYARYEDLKPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDAAAPPPANM 494

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1879298482 1942 IKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSR-VKATPMPSRPSTTPFIDKKPTSAKPS 2019
Cdd:PLN03209   495 RPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHhAQPKPRPLSPYTMYEDLKPPTSPTPS 573
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1792-1990 9.14e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 9.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1792 TPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLP--KQPAPTTIGGLNKKPMSLASGLVPAAPP-----KRPAVA 1864
Cdd:PRK12323   396 APAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAaaRQASARGPGGAPAPAPAPAAAPAAAARPaaagpRPVAAA 475

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1865 SARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPAsrsgSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPkKPTAIKT 1944
Cdd:PRK12323   476 AAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPA----QPDAAPAGWVAESIPDPATADPDDAFETLAP-APAAAPA 550

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1879298482 1945 EGKPAEVKKMTAkSVPADLSRPkSTSTSSMKKTTTLSGTAPAAGVV 1990
Cdd:PRK12323   551 PRAAAATEPVVA-PRPPRASAS-GLPDMFDGDWPALAARLPVRGLA 594
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1805-2209 9.38e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 41.06  E-value: 9.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1805 KTKPLATTQPAKTSTSKAKTQPTSLPKQ-----PAPTTIGGLnkkPMSlasglvPAAPPKRPAVASARPSILPSKDVKPK 1879
Cdd:pfam05109  407 RTATNATTTTHKVIFSKAPESTTTSPTLnttgfAAPNTTTGL---PSS------THVPTNLTAPASTGPTVSTADVTSPT 477

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1880 PIADAKApekrASPSKPASAPasrsgskstqtvaktttaaavASTGPSSRSPSTllpKKPTAIKTEGKPAEVKKMTAKSV 1959
Cdd:pfam05109  478 PAGTTSG----ASPVTPSPSP---------------------RDNGTESKAPDM---TSPTSAVTTPTPNATSPTPAVTT 529

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 1960 PAdlsrPKSTSTSSMKKTTTLSGTAPAAGVV-PSRVKATPMPSrpSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLK 2038
Cdd:pfam05109  530 PT----PNATSPTLGKTSPTSAVTTPTPNATsPTPAVTTPTPN--ATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQAN 603

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 2039 NVRSKVGST----------ENIKHQPGGGRVQIVSKKV--------SYSHIQSKCGSKDNIKHVP--------GGGNVqi 2092
Cdd:pfam05109  604 TTNHTLGGTsstpvvtsppKNATSAVTTGQHNITSSSTssmslrpsSISETLSPSTSDNSTSHMPlltsahptGGENI-- 681

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1879298482 2093 qnKKVDISKVSSKCGSKANIKHKPGggdvkiesqklnfkEKAQAKvGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGE 2172
Cdd:pfam05109  682 --TQVTPASTSTHHVSTSSPAPRPG--------------TTSQAS-GPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQ 744

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1879298482 2173 EPAISEAAPEAGAPTSASG---LNGH-------PTLSGGGDQREAQT 2209
Cdd:pfam05109  745 KTAVPTVTSTGGKANSTTGgkhTTGHgartstePTTDYGGDSTTPRT 791
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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