|
Name |
Accession |
Description |
Interval |
E-value |
| R3H_encore_like |
cd02642 |
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ... |
163-224 |
4.45e-26 |
|
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.
:
Pssm-ID: 100071 Cd Length: 63 Bit Score: 101.53 E-value: 4.45e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1876941748 163 DRMILLKMEQEIIDFIADNNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG-KSVIINKT 224
Cdd:cd02642 1 DRLFVLKLEKDLLAFIKDSTRQSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGgKCVIVNKT 63
|
|
| PAT1 super family |
cl37801 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
573-760 |
6.64e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
The actual alignment was detected with superfamily member pfam09770:
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.49 E-value: 6.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 573 PPSGPVYPSSLmPQPAQQPSYVIASTG-----QQLPTGGFSGSGPPISQQVLQPPPSPqgfvQQPPPAQMPVYYYPSGQY 647
Cdd:pfam09770 166 APKKAAAPAPA-PQPAAQPASLPAPSRkmmslEEVEAAMRAQAKKPAQQPAPAPAQPP----AAPPAQQAQQQQQFPPQI 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 648 PTSTTQQYRPMAPVQYNAQrsqqmpqaaqqaGYQPVLSGQQGFQGLIGVQQPPQSQNVINNQQGTPVQS---------VM 718
Cdd:pfam09770 241 QQQQQPQQQPQQPQQHPGQ------------GHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVqptqilqnpNR 308
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1876941748 719 VSYPTMSSYQVPMTQGSQGLPQQSYQQPIMLPNQAGQGSLPA 760
Cdd:pfam09770 309 LSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPIITHPQ 350
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
393-660 |
1.61e-03 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 393 PPLQSTPLVSGVAAGSPGCVPYPENGIGGQVAPSSTSYILLPLEAATGIPPGSillnphtgqpfVNPDGTPAIYNPPTSQ 472
Cdd:PHA03247 2701 PPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG-----------PARPARPPTTAGPPAP 2769
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 473 QPLRSAMVGQSQQQPPQQQPSPQPQQQVQPPQPQMAGPlvTQSVQGLQASSQSVQYPAVSFPPqhllPVSPTQhfpmrdd 552
Cdd:PHA03247 2770 APPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP--PAAVLAPAAALPPAASPAGPLPP----PTSAQP------- 2836
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 553 vatqfgqmtlsrqssgETPEPPSGPVyPSSLMPQPAQQPSYVIASTG--QQLPTGGFSGSGPPISQqVLQPPPSPQGFVQ 630
Cdd:PHA03247 2837 ----------------TAPPPPPGPP-PPSLPLGGSVAPGGDVRRRPpsRSPAAKPAAPARPPVRR-LARPAVSRSTESF 2898
|
250 260 270
....*....|....*....|....*....|.
gi 1876941748 631 -QPPPAQMPVYYYPSGQYPTSTTQQYRPMAP 660
Cdd:PHA03247 2899 aLPPDQPERPPQPQAPPPPQPQPQPPPPPQP 2929
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| R3H_encore_like |
cd02642 |
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ... |
163-224 |
4.45e-26 |
|
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.
Pssm-ID: 100071 Cd Length: 63 Bit Score: 101.53 E-value: 4.45e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1876941748 163 DRMILLKMEQEIIDFIADNNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG-KSVIINKT 224
Cdd:cd02642 1 DRLFVLKLEKDLLAFIKDSTRQSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGgKCVIVNKT 63
|
|
| R3H |
smart00393 |
Putative single-stranded nucleic acids-binding domain; |
147-224 |
1.38e-14 |
|
Putative single-stranded nucleic acids-binding domain;
Pssm-ID: 214647 Cd Length: 79 Bit Score: 69.25 E-value: 1.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 147 IDLHEFLINTLKNNSRDRMILLKMEQEIIDFIAdNNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG--KSVIINKT 224
Cdd:smart00393 1 ADFLPVTLDALSYRPRRREELIELELEIARFVK-STKESVELPPMNSYERKIVHELAEKYGLESESFGEGpkRRVVISKK 79
|
|
| R3H |
pfam01424 |
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most ... |
165-223 |
1.73e-12 |
|
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA.
Pssm-ID: 460206 Cd Length: 60 Bit Score: 62.90 E-value: 1.73e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1876941748 165 MILLKMEQEIIDFIADNNNHYKkFPQMSSYQRMLVHRVAAYFGLDHNV--DQTGKSVIINK 223
Cdd:pfam01424 1 EFLEQLAEKLAEFVKDTGKSLE-LPPMSSYERRIIHELAQKYGLESESegEEPNRRVVVYK 60
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
573-760 |
6.64e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.49 E-value: 6.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 573 PPSGPVYPSSLmPQPAQQPSYVIASTG-----QQLPTGGFSGSGPPISQQVLQPPPSPqgfvQQPPPAQMPVYYYPSGQY 647
Cdd:pfam09770 166 APKKAAAPAPA-PQPAAQPASLPAPSRkmmslEEVEAAMRAQAKKPAQQPAPAPAQPP----AAPPAQQAQQQQQFPPQI 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 648 PTSTTQQYRPMAPVQYNAQrsqqmpqaaqqaGYQPVLSGQQGFQGLIGVQQPPQSQNVINNQQGTPVQS---------VM 718
Cdd:pfam09770 241 QQQQQPQQQPQQPQQHPGQ------------GHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVqptqilqnpNR 308
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1876941748 719 VSYPTMSSYQVPMTQGSQGLPQQSYQQPIMLPNQAGQGSLPA 760
Cdd:pfam09770 309 LSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPIITHPQ 350
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
393-660 |
1.61e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 393 PPLQSTPLVSGVAAGSPGCVPYPENGIGGQVAPSSTSYILLPLEAATGIPPGSillnphtgqpfVNPDGTPAIYNPPTSQ 472
Cdd:PHA03247 2701 PPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG-----------PARPARPPTTAGPPAP 2769
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 473 QPLRSAMVGQSQQQPPQQQPSPQPQQQVQPPQPQMAGPlvTQSVQGLQASSQSVQYPAVSFPPqhllPVSPTQhfpmrdd 552
Cdd:PHA03247 2770 APPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP--PAAVLAPAAALPPAASPAGPLPP----PTSAQP------- 2836
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 553 vatqfgqmtlsrqssgETPEPPSGPVyPSSLMPQPAQQPSYVIASTG--QQLPTGGFSGSGPPISQqVLQPPPSPQGFVQ 630
Cdd:PHA03247 2837 ----------------TAPPPPPGPP-PPSLPLGGSVAPGGDVRRRPpsRSPAAKPAAPARPPVRR-LARPAVSRSTESF 2898
|
250 260 270
....*....|....*....|....*....|.
gi 1876941748 631 -QPPPAQMPVYYYPSGQYPTSTTQQYRPMAP 660
Cdd:PHA03247 2899 aLPPDQPERPPQPQAPPPPQPQPQPPPPPQP 2929
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
574-766 |
3.70e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 40.84 E-value: 3.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 574 PSGPVYPSSLMPQPAQQPSYVIASTgQQLPtggfsgsGPPISQQVLQPppSPQGFVQQPPPAQmpvyyyPSGQYPTSTTQ 653
Cdd:PRK10263 336 PVEPVTQTPPVASVDVPPAQPTVAW-QPVP-------GPQTGEPVIAP--APEGYPQQSQYAQ------PAVQYNEPLQQ 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 654 QYRPMAPVQYNAQRSQQMPQAAQQAGYQPVLSGQQGFQgligVQQPPQSQNVINNQQGTPVQSvMVSYPTMSSYQVPMTQ 733
Cdd:PRK10263 400 PVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPA----PEQPVAGNAWQAEEQQSTFAP-QSTYQTEQTYQQPAAQ 474
|
170 180 190
....*....|....*....|....*....|...
gi 1876941748 734 GSQGLPQQSYQQPIMLPNQAGQGSLPATGMPVY 766
Cdd:PRK10263 475 EPLYQQPQPVEQQPVVEPEPVVEETKPARPPLY 507
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| R3H_encore_like |
cd02642 |
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ... |
163-224 |
4.45e-26 |
|
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.
Pssm-ID: 100071 Cd Length: 63 Bit Score: 101.53 E-value: 4.45e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1876941748 163 DRMILLKMEQEIIDFIADNNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG-KSVIINKT 224
Cdd:cd02642 1 DRLFVLKLEKDLLAFIKDSTRQSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGgKCVIVNKT 63
|
|
| R3H |
smart00393 |
Putative single-stranded nucleic acids-binding domain; |
147-224 |
1.38e-14 |
|
Putative single-stranded nucleic acids-binding domain;
Pssm-ID: 214647 Cd Length: 79 Bit Score: 69.25 E-value: 1.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 147 IDLHEFLINTLKNNSRDRMILLKMEQEIIDFIAdNNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG--KSVIINKT 224
Cdd:smart00393 1 ADFLPVTLDALSYRPRRREELIELELEIARFVK-STKESVELPPMNSYERKIVHELAEKYGLESESFGEGpkRRVVISKK 79
|
|
| R3H |
pfam01424 |
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most ... |
165-223 |
1.73e-12 |
|
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA.
Pssm-ID: 460206 Cd Length: 60 Bit Score: 62.90 E-value: 1.73e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1876941748 165 MILLKMEQEIIDFIADNNNHYKkFPQMSSYQRMLVHRVAAYFGLDHNV--DQTGKSVIINK 223
Cdd:pfam01424 1 EFLEQLAEKLAEFVKDTGKSLE-LPPMSSYERRIIHELAQKYGLESESegEEPNRRVVVYK 60
|
|
| R3H |
cd02325 |
R3H domain. The name of the R3H domain comes from the characteristic spacing of the most ... |
167-223 |
1.81e-12 |
|
R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich repeats, ring-type zinc fingers, and KH domains. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.
Pssm-ID: 100064 Cd Length: 59 Bit Score: 62.63 E-value: 1.81e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1876941748 167 LLKMEQEIIDFIADNNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG--KSVIINK 223
Cdd:cd02325 1 REEREEELEAFAKDAAGKSLELPPMNSYERKLIHDLAEYYGLKSESEGEGpnRRVVITK 59
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
573-760 |
6.64e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.49 E-value: 6.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 573 PPSGPVYPSSLmPQPAQQPSYVIASTG-----QQLPTGGFSGSGPPISQQVLQPPPSPqgfvQQPPPAQMPVYYYPSGQY 647
Cdd:pfam09770 166 APKKAAAPAPA-PQPAAQPASLPAPSRkmmslEEVEAAMRAQAKKPAQQPAPAPAQPP----AAPPAQQAQQQQQFPPQI 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 648 PTSTTQQYRPMAPVQYNAQrsqqmpqaaqqaGYQPVLSGQQGFQGLIGVQQPPQSQNVINNQQGTPVQS---------VM 718
Cdd:pfam09770 241 QQQQQPQQQPQQPQQHPGQ------------GHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVqptqilqnpNR 308
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1876941748 719 VSYPTMSSYQVPMTQGSQGLPQQSYQQPIMLPNQAGQGSLPA 760
Cdd:pfam09770 309 LSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPIITHPQ 350
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
393-660 |
1.61e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 393 PPLQSTPLVSGVAAGSPGCVPYPENGIGGQVAPSSTSYILLPLEAATGIPPGSillnphtgqpfVNPDGTPAIYNPPTSQ 472
Cdd:PHA03247 2701 PPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG-----------PARPARPPTTAGPPAP 2769
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 473 QPLRSAMVGQSQQQPPQQQPSPQPQQQVQPPQPQMAGPlvTQSVQGLQASSQSVQYPAVSFPPqhllPVSPTQhfpmrdd 552
Cdd:PHA03247 2770 APPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP--PAAVLAPAAALPPAASPAGPLPP----PTSAQP------- 2836
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 553 vatqfgqmtlsrqssgETPEPPSGPVyPSSLMPQPAQQPSYVIASTG--QQLPTGGFSGSGPPISQqVLQPPPSPQGFVQ 630
Cdd:PHA03247 2837 ----------------TAPPPPPGPP-PPSLPLGGSVAPGGDVRRRPpsRSPAAKPAAPARPPVRR-LARPAVSRSTESF 2898
|
250 260 270
....*....|....*....|....*....|.
gi 1876941748 631 -QPPPAQMPVYYYPSGQYPTSTTQQYRPMAP 660
Cdd:PHA03247 2899 aLPPDQPERPPQPQAPPPPQPQPQPPPPPQP 2929
|
|
| R3H_unknown_2 |
cd06006 |
R3H domain of a group of fungal proteins with unknown function. The name of the R3H domain ... |
169-209 |
2.22e-03 |
|
R3H domain of a group of fungal proteins with unknown function. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.
Pssm-ID: 100076 Cd Length: 59 Bit Score: 36.96 E-value: 2.22e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 1876941748 169 KMEQEIIDFIADNNNHYKKFPQMSSYQRMLVHRVAAYFGLD 209
Cdd:cd06006 3 QIESTLRKFINDKSKRSLRFPPMRSPQRAFIHELAKDYGLY 43
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
390-809 |
2.23e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 2.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 390 RTHPPLQSTPLVSGVAAGS----PGCVPYPENGIG---------GQVAPSStsyilLPLEAATGIPPgsillnPHTGQPF 456
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPAVTSrarrPDAPPQSARPRApvddrgdprGPAPPSP-----LPPDTHAPDPP------PPSPSPA 2634
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 457 VNPDGTPAIYNPPTSQQPLRSAMVGQSQQQPPQQQPSPQPQQQVQPPQ-PQMAGPLVTQSVQGL------QASSQSVQYP 529
Cdd:PHA03247 2635 ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRpRRRAARPTVGSLTSLadppppPPTPEPAPHA 2714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 530 AVSFPPQHLLPVSPTQHFPMR----------DDVATQFGQMTLSRQSSGETPEPPSGPVYPSS----------------- 582
Cdd:PHA03247 2715 LVSATPLPPGPAAARQASPALpaapappavpAGPATPGGPARPARPPTTAGPPAPAPPAAPAAgpprrltrpavaslses 2794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 583 -----LMPQPAQQPSYVIASTGQQLPTGGFSGSGPPISQQVLQPPPSPQGFVqqPPPAQMPVYYYPSGQY---PTSTTQQ 654
Cdd:PHA03247 2795 reslpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPP--PPSLPLGGSVAPGGDVrrrPPSRSPA 2872
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 655 YRPMAPVQYNAQRSQqmpqaaqqagyQPVLSGQQGFQGLIGVQQPPQSQNVINNQQGTPVQSVMVSYPTMSsyqvPMTQG 734
Cdd:PHA03247 2873 AKPAAPARPPVRRLA-----------RPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP----PPPPP 2937
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1876941748 735 SQGLPQQSYQQPIMLPNQAGQGSLPATGMPVYCNVTPPTpqnnlRLIGPHCPSSTVPVMSASCRTNCASMSNAGW 809
Cdd:PHA03247 2938 RPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPR-----FRVPQPAPSREAPASSTPPLTGHSLSRVSSW 3007
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
472-810 |
3.07e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.29 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 472 QQPLRSAMVGQSQQQPPQQQPSPQPQQQVQPPQPQMAGPLVTQSVQGLQASSQSVQYPAVSFPPQHLLPVSPTQHFPMRD 551
Cdd:pfam03154 164 QQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLP 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 552 DVATQFGQMTLSRQSSGETPEPPSGPVY--PSSLMPQPAQ------------QPSYVIASTGQ-QLPTGGFSGSGPPISQ 616
Cdd:pfam03154 244 SPHPPLQPMTQPPPPSQVSPQPLPQPSLhgQMPPMPHSLQtgpshmqhpvppQPFPLTPQSSQsQVPPGPSPAAPGQSQQ 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 617 QVLQPPPSPQGFVQQP------PPAQMPVyyyPSGQYPTSTtqqyrPMAPVQyNAQRSQqmpqaaqqagYQPVLSGQQGF 690
Cdd:pfam03154 324 RIHTPPSQSQLQSQQPpreqplPPAPLSM---PHIKPPPTT-----PIPQLP-NPQSHK----------HPPHLSGPSPF 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 691 QGLIGVQQPPQSQnvinnqqgtPVQSVMVSYPTmSSYQVP---MTQgSQGLPQQSYQQPIMLPNQ---AGQGSLPATGMP 764
Cdd:pfam03154 385 QMNSNLPPPPALK---------PLSSLSTHHPP-SAHPPPlqlMPQ-SQQLPPPPAQPPVLTQSQslpPPAASHPPTSGL 453
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1876941748 765 VYCNVTPPTPQNnlrligPHCPSSTVPVMSASCRTNCASMSNAGWQ 810
Cdd:pfam03154 454 HQVPSQSPFPQH------PFVPGGPPPITPPSGPPTSTSSAMPGIQ 493
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
450-774 |
3.26e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.29 E-value: 3.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 450 PHTGQPFVNPDGTPAIYNPPTSQQPLRSAMvgQSQQQPPQQQPSPQPQQQVQPPQPQMAGPLVTQSVQGLQASSQSVQYP 529
Cdd:pfam03154 199 PTPSAPSVPPQGSPATSQPPNQTQSTAAPH--TLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMP 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 530 AVSFP----PQHLLPVSPTQHFPMRDDVATQFGQMTLSRQSSGETPEPPSGPvyPSSLMPQPAQQPSYviastgQQLPTG 605
Cdd:pfam03154 277 PMPHSlqtgPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTP--PSQSQLQSQQPPRE------QPLPPA 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 606 gfsgsgpPISQQVLQPPPS--------PQG-----FVQQPPPAQMPVYY-YPSGQYPTSTTQQYRPMAPVQYNAQRSQQM 671
Cdd:pfam03154 349 -------PLSMPHIKPPPTtpipqlpnPQShkhppHLSGPSPFQMNSNLpPPPALKPLSSLSTHHPPSAHPPPLQLMPQS 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 672 PQAAQQAGYQPVLSGQQGFQGLIGVQQPPQSQNVINNQQGTPVQSVMVSYPT-MSSYQVPMTQGSQGLPqqSYQQPIMLP 750
Cdd:pfam03154 422 QQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPpITPPSGPPTSTSSAMP--GIQPPSSAS 499
|
330 340
....*....|....*....|....
gi 1876941748 751 nqagqgslPATGMPVYCNVTPPTP 774
Cdd:pfam03154 500 --------VSSSGPVPAAVSCPLP 515
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
574-766 |
3.70e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 40.84 E-value: 3.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 574 PSGPVYPSSLMPQPAQQPSYVIASTgQQLPtggfsgsGPPISQQVLQPppSPQGFVQQPPPAQmpvyyyPSGQYPTSTTQ 653
Cdd:PRK10263 336 PVEPVTQTPPVASVDVPPAQPTVAW-QPVP-------GPQTGEPVIAP--APEGYPQQSQYAQ------PAVQYNEPLQQ 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 654 QYRPMAPVQYNAQRSQQMPQAAQQAGYQPVLSGQQGFQgligVQQPPQSQNVINNQQGTPVQSvMVSYPTMSSYQVPMTQ 733
Cdd:PRK10263 400 PVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPA----PEQPVAGNAWQAEEQQSTFAP-QSTYQTEQTYQQPAAQ 474
|
170 180 190
....*....|....*....|....*....|...
gi 1876941748 734 GSQGLPQQSYQQPIMLPNQAGQGSLPATGMPVY 766
Cdd:PRK10263 475 EPLYQQPQPVEQQPVVEPEPVVEETKPARPPLY 507
|
|
| R3H_Smubp-2_like |
cd02641 |
R3H domain of Smubp-2_like proteins. Smubp-2_like proteins also contain a helicase_like and ... |
174-221 |
4.33e-03 |
|
R3H domain of Smubp-2_like proteins. Smubp-2_like proteins also contain a helicase_like and an AN1-like Zinc finger domain and have been shown to bind single-stranded DNA. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA.
Pssm-ID: 100070 Cd Length: 60 Bit Score: 36.18 E-value: 4.33e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 1876941748 174 IIDFIADNNNHYKKFP-QMSSYQRMLVHRVAAYFGLDHNVDQTGKSVII 221
Cdd:cd02641 8 VKAFMKDPKATELEFPpTLSSHDRLLVHELAEELGLRHESTGEGSDRVI 56
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
566-662 |
5.49e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 40.14 E-value: 5.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1876941748 566 SSGETPEPPSGP---VYPSSLMPQPAQQPSYVIASTGQQLPTGgfSGSGPPISQQVLQPPPS-PQGFVQQPPPAQMPVYY 641
Cdd:PRK14971 364 QKGDDASGGRGPkqhIKPVFTQPAAAPQPSAAAAASPSPSQSS--AAAQPSAPQSATQPAGTpPTVSVDPPAAVPVNPPS 441
|
90 100
....*....|....*....|.
gi 1876941748 642 YPSGQYPTSTTQQYRPMAPVQ 662
Cdd:PRK14971 442 TAPQAVRPAQFKEEKKIPVSK 462
|
|
| |
