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Conserved domains on  [gi|1862722961|ref|NP_001371769|]
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microtubule-associated protein 4 isoform 95 [Homo sapiens]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 882-911 1.06e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 1.06e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1862722961  882 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 911
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 913-942 1.70e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.12  E-value: 1.70e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1862722961  913 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 942
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 944-974 3.53e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.80  E-value: 3.53e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1862722961  944 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 974
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 859-880 1.88e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.87  E-value: 1.88e-08
                           10        20
                   ....*....|....*....|..
gi 1862722961  859 DLKNVRSKVGSTENIKHQPGGG 880
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 647-858 9.73e-04

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 9.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  647 KLGERKPCNSQPSELSSETSGIARPEEGRPVVS-GTGNDITTPPNKELPPSPEKKTKPIADAkapekrASPSKPASAPAS 725
Cdd:PHA03247  2637 EPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRlGRAAQASSPPQRPRRRAARPTVGSLTSL------ADPPPPPPTPEP 2710

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  726 RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTtlsg 805
Cdd:PHA03247  2711 APHALVSATPLPPGPAAARQASPALPAAPAP--PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT---- 2784

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1862722961  806 tAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 858
Cdd:PHA03247  2785 -RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 882-911 1.06e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 1.06e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1862722961  882 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 911
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 913-942 1.70e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.12  E-value: 1.70e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1862722961  913 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 942
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 944-974 3.53e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.80  E-value: 3.53e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1862722961  944 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 974
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 859-880 1.88e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.87  E-value: 1.88e-08
                           10        20
                   ....*....|....*....|..
gi 1862722961  859 DLKNVRSKVGSTENIKHQPGGG 880
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 647-858 9.73e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 9.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  647 KLGERKPCNSQPSELSSETSGIARPEEGRPVVS-GTGNDITTPPNKELPPSPEKKTKPIADAkapekrASPSKPASAPAS 725
Cdd:PHA03247  2637 EPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRlGRAAQASSPPQRPRRRAARPTVGSLTSL------ADPPPPPPTPEP 2710

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  726 RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTtlsg 805
Cdd:PHA03247  2711 APHALVSATPLPPGPAAARQASPALPAAPAP--PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT---- 2784

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1862722961  806 tAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 858
Cdd:PHA03247  2785 -RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 882-911 1.06e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 1.06e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1862722961  882 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 911
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 913-942 1.70e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.12  E-value: 1.70e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 1862722961  913 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 942
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 944-974 3.53e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.80  E-value: 3.53e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1862722961  944 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 974
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 859-880 1.88e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.87  E-value: 1.88e-08
                           10        20
                   ....*....|....*....|..
gi 1862722961  859 DLKNVRSKVGSTENIKHQPGGG 880
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 647-858 9.73e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 9.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  647 KLGERKPCNSQPSELSSETSGIARPEEGRPVVS-GTGNDITTPPNKELPPSPEKKTKPIADAkapekrASPSKPASAPAS 725
Cdd:PHA03247  2637 EPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRlGRAAQASSPPQRPRRRAARPTVGSLTSL------ADPPPPPPTPEP 2710

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  726 RSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTtlsg 805
Cdd:PHA03247  2711 APHALVSATPLPPGPAAARQASPALPAAPAP--PAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT---- 2784

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1862722961  806 tAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 858
Cdd:PHA03247  2785 -RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
PRK13914 PRK13914
invasion associated endopeptidase;
656-872 1.45e-03

invasion associated endopeptidase;


Pssm-ID: 237555 [Multi-domain]  Cd Length: 481  Bit Score: 42.48  E-value: 1.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  656 SQPSELSSETSGIARPEEGRPVV-SGTGNDITTPPNKELPPSPEKKTKPIADAKAPEKRASPSKPASAPASRSGSKSTQT 734
Cdd:PRK13914   145 STPVAPTQEVKKETTTQQAAPAAeTKTEVKQTTQATTPAPKVAETKETPVVDQNATTHAVKSGDTIWALSVKYGVSVQDI 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  735 VAKTTTAAAVASTGPS---SRSPSTLLPKkpTAIKTEGKPAEvkKMTAKSVPADLSrpKSTSTSSMKKTTTLSGTAPAAG 811
Cdd:PRK13914   225 MSWNNLSSSSIYVGQKlaiKQTANTATPK--AEVKTEAPAAE--KQAAPVVKENTN--TNTATTEKKETTTQQQTAPKAP 298

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862722961  812 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP-RLSRLATNTSAPDLKNVRSKVGSTEN 872
Cdd:PRK13914   299 TEAAKPAPAPSTNTNANKTNTNTNTNTNNTNTSTPsKNTNTNTNSNTNTNSNTNANQGSSNN 360
PHA03247 PHA03247
large tegument protein UL36; Provisional
 575-852 4.18e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 4.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  575 DVPPLSETEATPVPIKDMEIAQTQKGISE-DSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLeKLGERKP 653
Cdd:PHA03247  2590 DAPPQSARPRAPVDDRGDPRGPAPPSPLPpDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRV-SRPRRAR 2668

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  654 CNSQPSELSSETSGiARPEEGRPVVsGTGNDITTPPNKELPPSPEKK----TKPIADAKAPEKRASPSKP--------AS 721
Cdd:PHA03247  2669 RLGRAAQASSPPQR-PRRRAARPTV-GSLTSLADPPPPPPTPEPAPHalvsATPLPPGPAAARQASPALPaapappavPA 2746

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  722 APASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTT 801
Cdd:PHA03247  2747 GPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG 2826

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1862722961  802 TLsgtAPAAGVVPSRVKATPMPSRPSTT---------PFIDKKPTSAKP----SSTTPRLSRLA 852
Cdd:PHA03247  2827 PL---PPPTSAQPTAPPPPPGPPPPSLPlggsvapggDVRRRPPSRSPAakpaAPARPPVRRLA 2887
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 692-841 5.29e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.83  E-value: 5.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  692 ELPPSPEKKTKPI---ADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS-----SRSPStlLPKKPT 763
Cdd:PTZ00449   509 EPPEGPEASGLPPkapGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKPE--FPKDPK 586

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  764 AIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL--SGTAPAAGVVPSRVKAtpmPSRPSTT--PFIDKKPTSA 839
Cdd:PTZ00449   587 HPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRpeSPKSPKRPPPPQRPSS---PERPEGPkiIKSPKPPKSP 663


                   ..
gi 1862722961  840 KP 841
Cdd:PTZ00449   664 KP 665
PHA03247 PHA03247
large tegument protein UL36; Provisional
 653-847 5.57e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 5.57e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  653 PCNSQPSELSSETSGIARPEEGRPVVSGTGNDittPPNKELPPSPEKKTKPIADAKAPEKRASPSK-----PASAPASRS 727
Cdd:PHA03247  2575 PRPSEPAVTSRARRPDAPPQSARPRAPVDDRG---DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEpdphpPPTVPPPER 2651

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  728 GSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAiktegkPAEVKKMTAKSVPADLSR---PKSTSTSSMKKTTTLS 804
Cdd:PHA03247  2652 PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAA------RPTVGSLTSLADPPPPPPtpePAPHALVSATPLPPGP 2725

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1862722961  805 GTAPAAGVVPSRVKATPMPSRPSTTPFIDKKP-----TSAKPSSTTPR 847
Cdd:PHA03247  2726 AAARQASPALPAAPAPPAVPAGPATPGGPARParpptTAGPPAPAPPA 2773
PHA03247 PHA03247
large tegument protein UL36; Provisional
 549-854 6.06e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 6.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  549 VPALKTEAPLAKDGVLTLANNVTPAKdvPPLSETEATPVPIKDMEIAQTQKGisedshleslqdvgqSAAPTfmisPETV 628
Cdd:PHA03247  2716 VSATPLPPGPAAARQASPALPAAPAP--PAVPAGPATPGGPARPARPPTTAG---------------PPAPA----PPAA 2774

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  629 TGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSG--IARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPIAD 706
Cdd:PHA03247  2775 PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLApaAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGG 2854

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  707 AKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADL 786
Cdd:PHA03247  2855 SVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPP 2934

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722961  787 SRPKSTS----TSSMKKTTTLSGTAPA---AGVVPSRVKAT------PMPSRPSTTPfidkkPTSAKPSSTTPRLSRLAT 853
Cdd:PHA03247  2935 PPPRPQPplapTTDPAGAGEPSGAVPQpwlGALVPGRVAVPrfrvpqPAPSREAPAS-----STPPLTGHSLSRVSSWAS 3009


                   .
gi 1862722961  854 N 854
Cdd:PHA03247  3010 S 3010
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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