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Conserved domains on  [gi|1862722903|ref|NP_001371764|]
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microtubule-associated protein 4 isoform 134 [Homo sapiens]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 392-421 4.43e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 63.20  E-value: 4.43e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862722903 392 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 421
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 423-453 7.30e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 51.26  E-value: 7.30e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862722903 423 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 453
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 369-390 3.39e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 49.33  E-value: 3.39e-08
                          10        20
                  ....*....|....*....|..
gi 1862722903 369 DLKNVRSKVGSTENIKHQPGGG 390
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 166-368 1.06e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903  166 AGQNDPLKDSYGIARPEEGRPVVSGTGNDITTPPNKELPPSPekkTKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV 245
Cdd:PHA03247  2728 ARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAP---APPAAPAAGPPRRLTRPAVASLSESRESLPSPWDP 2804

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903  246 AKTTTA-AAVASTGPSSRSPSTLLPKKPTAI-----KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGtapa 319
Cdd:PHA03247  2805 ADPPAAvLAPAAALPPAASPAGPLPPPTSAQptappPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPAR---- 2880

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1862722903  320 agvVPSRVKATPMPSR-------PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 368
Cdd:PHA03247  2881 ---PPVRRLARPAVSRstesfalPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 392-421 4.43e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 63.20  E-value: 4.43e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862722903 392 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 421
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 423-453 7.30e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 51.26  E-value: 7.30e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862722903 423 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 453
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 369-390 3.39e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 49.33  E-value: 3.39e-08
                          10        20
                  ....*....|....*....|..
gi 1862722903 369 DLKNVRSKVGSTENIKHQPGGG 390
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 166-368 1.06e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903  166 AGQNDPLKDSYGIARPEEGRPVVSGTGNDITTPPNKELPPSPekkTKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV 245
Cdd:PHA03247  2728 ARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAP---APPAAPAAGPPRRLTRPAVASLSESRESLPSPWDP 2804

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903  246 AKTTTA-AAVASTGPSSRSPSTLLPKKPTAI-----KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGtapa 319
Cdd:PHA03247  2805 ADPPAAvLAPAAALPPAASPAGPLPPPTSAQptappPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPAR---- 2880

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1862722903  320 agvVPSRVKATPMPSR-------PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 368
Cdd:PHA03247  2881 ---PPVRRLARPAVSRstesfalPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 231-505 2.12e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.14  E-value: 2.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 231 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllpkkptaiKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 310
Cdd:pfam05109 459 TAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSP---------RDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTT 529

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 311 TTLSGTAPAAG-VVPSRVKATPMPSRPSTTPFIdkkpTSAKPSSTTPRLSRLATNT--SAPDLKNVRSKVGSTENIKHQP 387
Cdd:pfam05109 530 PTPNATSPTLGkTSPTSAVTTPTPNATSPTPAV----TTPTPNATIPTLGKTSPTSavTTPTPNATSPTVGETSPQANTT 605

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 388 GGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLC 467
Cdd:pfam05109 606 NHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVT 685

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1862722903 468 PGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGD 505
Cdd:pfam05109 686 PASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGE 723
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 392-421 4.43e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 63.20  E-value: 4.43e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862722903 392 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 421
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 423-453 7.30e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 51.26  E-value: 7.30e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862722903 423 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 453
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 369-390 3.39e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 49.33  E-value: 3.39e-08
                          10        20
                  ....*....|....*....|..
gi 1862722903 369 DLKNVRSKVGSTENIKHQPGGG 390
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 166-368 1.06e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903  166 AGQNDPLKDSYGIARPEEGRPVVSGTGNDITTPPNKELPPSPekkTKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV 245
Cdd:PHA03247  2728 ARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAP---APPAAPAAGPPRRLTRPAVASLSESRESLPSPWDP 2804

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903  246 AKTTTA-AAVASTGPSSRSPSTLLPKKPTAI-----KTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGtapa 319
Cdd:PHA03247  2805 ADPPAAvLAPAAALPPAASPAGPLPPPTSAQptappPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPAR---- 2880

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1862722903  320 agvVPSRVKATPMPSR-------PSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 368
Cdd:PHA03247  2881 ---PPVRRLARPAVSRstesfalPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 231-505 2.12e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.14  E-value: 2.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 231 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllpkkptaiKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 310
Cdd:pfam05109 459 TAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSP---------RDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTT 529

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 311 TTLSGTAPAAG-VVPSRVKATPMPSRPSTTPFIdkkpTSAKPSSTTPRLSRLATNT--SAPDLKNVRSKVGSTENIKHQP 387
Cdd:pfam05109 530 PTPNATSPTLGkTSPTSAVTTPTPNATSPTPAV----TTPTPNATIPTLGKTSPTSavTTPTPNATSPTVGETSPQANTT 605

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 388 GGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLC 467
Cdd:pfam05109 606 NHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVT 685

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1862722903 468 PGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGD 505
Cdd:pfam05109 686 PASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGE 723
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 202-351 2.14e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.83  E-value: 2.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 202 ELPPSPEKKTKPI---ADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS-----SRSPStlLPKKPT 273
Cdd:PTZ00449  509 EPPEGPEASGLPPkapGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKPE--FPKDPK 586

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 274 AIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL--SGTAPAAGVVPSRVKAtpmPSRPSTT--PFIDKKPTSA 349
Cdd:PTZ00449  587 HPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRpeSPKSPKRPPPPQRPSS---PERPEGPkiIKSPKPPKSP 663


                  ..
gi 1862722903 350 KP 351
Cdd:PTZ00449  664 KP 665
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 148-375 2.35e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.92  E-value: 2.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903  148 DLADLVFPSSATADTSIFAGQNDPLKDSYG----IARPEEGRPVVSGTGNDITTPPNKELPPSPekktKPIADAKAPEKR 223
Cdd:PHA03307    12 EAAAEGGEFFPRPPATPGDAADDLLSGSQGqlvsDSAELAAVTVVAGAAACDRFEPPTGPPPGP----GTEAPANESRST 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903  224 A--SPSKPASAPASRSGSkstqtvaktTTAAAVASTGPSSRSPSTLLPKKPTAIKTegkpAEVKKMTAKSVPADLSRPKS 301
Cdd:PHA03307    88 PtwSLSTLAPASPAREGS---------PTPPGPSSPDPPPPTPPPASPPPSPAPDL----SEMLRPVGSPGPPPAASPPA 154

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1862722903  302 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSStTPRLSRLATNTSAPDLKNVRS 375
Cdd:PHA03307   155 AGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRP-PRRSSPISASASSPAPAPGRS 227
PHA03247 PHA03247
large tegument protein UL36; Provisional
 155-368 3.26e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 3.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903  155 PSSATADTSIFAGQNDPLKDSYGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPIADAKAPEKRA-SPSKPASA- 232
Cdd:PHA03247  2598 PRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRArRLGRAAQAs 2677

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903  233 --------PASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIK-----TEGKPAEVKKMTAKSVPADLSRP 299
Cdd:PHA03247  2678 sppqrprrRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARqaspaLPAAPAPPAVPAGPATPGGPARP 2757

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1862722903  300 KSTSTSSMKKTTT----------LSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 368
Cdd:PHA03247  2758 ARPPTTAGPPAPAppaapaagppRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
PRK13914 PRK13914
invasion associated endopeptidase;
196-382 3.51e-03

invasion associated endopeptidase;


Pssm-ID: 237555 [Multi-domain]  Cd Length: 481  Bit Score: 39.78  E-value: 3.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 196 TTPPNKELPPSPEKKTKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS---SRSPSTLLPKkp 272
Cdd:PRK13914  176 TTQATTPAPKVAETKETPVVDQNATTHAVKSGDTIWALSVKYGVSVQDIMSWNNLSSSSIYVGQKlaiKQTANTATPK-- 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 273 TAIKTEGKPAEvkKMTAKSVPADLSrpKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPS 352
Cdd:PRK13914  254 AEVKTEAPAAE--KQAAPVVKENTN--TNTATTEKKETTTQQQTAPKAPTEAAKPAPAPSTNTNANKTNTNTNTNTNNTN 329

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1862722903 353 STTP-RLSRLATNTSAPDLKNVRSKVGSTEN 382
Cdd:PRK13914  330 TSTPsKNTNTNTNSNTNTNSNTNANQGSSNN 360
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
189-356 4.09e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 39.83  E-value: 4.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 189 SGTGNDITTPPNKELPPSPEKKTKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLL 268
Cdd:PRK07003  366 GAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADG 445

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862722903 269 PKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTS 348
Cdd:PRK07003  446 DAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAA 525


                  ....*...
gi 1862722903 349 AKPSSTTP 356
Cdd:PRK07003  526 APPAPEAR 533
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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