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Conserved domains on  [gi|1862723050|ref|NP_001371744|]
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microtubule-associated protein 4 isoform 131 [Homo sapiens]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 464-493 5.83e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 62.81  E-value: 5.83e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862723050 464 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 493
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 180-429 2.27e-10

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.19  E-value: 2.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  180 RPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 259
Cdd:PHA03247  2684 RRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  260 AAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPS 337
Cdd:PHA03247  2761 PTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  338 TLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTT 411
Cdd:PHA03247  2841 PPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQ 2920

                          250
                   ....*....|....*...
gi 1862723050  412 PFIDKKPTSAKPSSTTPR 429
Cdd:PHA03247  2921 PQPPPPPQPQPPPPPPPR 2938
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 495-525 9.89e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.87  E-value: 9.89e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862723050 495 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 525
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 441-462 4.38e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 48.95  E-value: 4.38e-08
                          10        20
                  ....*....|....*....|..
gi 1862723050 441 DLKNVRSKVGSTENIKHQPGGG 462
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 464-493 5.83e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 62.81  E-value: 5.83e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862723050 464 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 493
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 180-429 2.27e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.19  E-value: 2.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  180 RPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 259
Cdd:PHA03247  2684 RRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  260 AAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPS 337
Cdd:PHA03247  2761 PTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  338 TLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTT 411
Cdd:PHA03247  2841 PPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQ 2920

                          250
                   ....*....|....*...
gi 1862723050  412 PFIDKKPTSAKPSSTTPR 429
Cdd:PHA03247  2921 PQPPPPPQPQPPPPPPPR 2938
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 495-525 9.89e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.87  E-value: 9.89e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862723050 495 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 525
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 441-462 4.38e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 48.95  E-value: 4.38e-08
                          10        20
                  ....*....|....*....|..
gi 1862723050 441 DLKNVRSKVGSTENIKHQPGGG 462
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 171-440 3.05e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 40.67  E-value: 3.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 171 PLKDSYGIARPEegrpVVSGTGNDITTPPNKELPPS--PEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK 248
Cdd:pfam05109 432 PTLNTTGFAAPN----TTTGLPSSTHVPTNLTAPAStgPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMT 507

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 249 KPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAS 328
Cdd:pfam05109 508 SPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPT 587

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 329 TGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTA--KSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRV--KATPM 404
Cdd:pfam05109 588 PNATSPTVGETSPQANTTNHTLGGTSSTPVVTSppKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSdnSTSHM 667

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1862723050 405 PSRPSTTPFIDKKPTSAKPSSTTPRlsRLATNTSAP 440
Cdd:pfam05109 668 PLLTSAHPTGGENITQVTPASTSTH--HVSTSSPAP 701
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 464-493 5.83e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 62.81  E-value: 5.83e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862723050 464 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 493
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 180-429 2.27e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 64.19  E-value: 2.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  180 RPEEGRPVVSGTGNDITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVP 259
Cdd:PHA03247  2684 RRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP 2760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  260 AAP--PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPS 337
Cdd:PHA03247  2761 PTTagPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  338 TLLPKKPTAIKTEGKPAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTT 411
Cdd:PHA03247  2841 PPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQ 2920

                          250
                   ....*....|....*...
gi 1862723050  412 PFIDKKPTSAKPSSTTPR 429
Cdd:PHA03247  2921 PQPPPPPQPQPPPPPPPR 2938
PHA03247 PHA03247
large tegument protein UL36; Provisional
 179-440 4.38e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 63.03  E-value: 4.38e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  179 ARPEEGRPVVSG--TGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGG---LNKKPMSL 253
Cdd:PHA03247  2591 APPQSARPRAPVddRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGrvsRPRRARRL 2670

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  254 ASGLVPAAPPKRPAVASARPSILPSKDvkpkpIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSS 333
Cdd:PHA03247  2671 GRAAQASSPPQRPRRRAARPTVGSLTS-----LADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVP 2745

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  334 RSPSTllPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTstssmkktttlsgtAPAAGVVPSRVKATPMPSRPSTTPF 413
Cdd:PHA03247  2746 AGPAT--PGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT--------------RPAVASLSESRESLPSPWDPADPPA 2809

                          250       260
                   ....*....|....*....|....*..
gi 1862723050  414 IDKKPTSAKPSSTTPRLSRLATNTSAP 440
Cdd:PHA03247  2810 AVLAPAAALPPAASPAGPLPPPTSAQP 2836
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 495-525 9.89e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 50.87  E-value: 9.89e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862723050 495 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 525
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 166-435 2.72e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 57.26  E-value: 2.72e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  166 AGQNDPLKDSYGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTS----LPKQPAPT 241
Cdd:PHA03247  2728 ARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESReslpSPWDPADP 2807

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  242 TIGGLNKKPmSLASGLVPAAP-PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKT 320
Cdd:PHA03247  2808 PAAVLAPAA-ALPPAASPAGPlPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRL 2886

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  321 TTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADlsRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVK 400
Cdd:PHA03247  2887 ARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP--PPPPRPQPPLAPTTDPAGAGEPSGAVPQPWL 2964

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 1862723050  401 ATPMPSRPSTTPFI--DKKPTSAKPSSTTPRLSRLAT 435
Cdd:PHA03247  2965 GALVPGRVAVPRFRvpQPAPSREAPASSTPPLTGHSL 3001
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 441-462 4.38e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 48.95  E-value: 4.38e-08
                          10        20
                  ....*....|....*....|..
gi 1862723050 441 DLKNVRSKVGSTENIKHQPGGG 462
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 155-434 2.39e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.09  E-value: 2.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  155 PSSATADTSIFAGQNDPLKDSYGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLA--TTQPAKTSTSKAKTQPT 232
Cdd:PHA03247  2598 PRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPgrVSRPRRARRLGRAAQAS 2677

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  233 SLPKQP----APTTIGGLN---------KKPMSLASGLVPAAPPkrPAVASARPSILPSKDVKPKPIADAKAPEKRASPS 299
Cdd:PHA03247  2678 SPPQRPrrraARPTVGSLTsladpppppPTPEPAPHALVSATPL--PPGPAAARQASPALPAAPAPPAVPAGPATPGGPA 2755

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  300 KPASaPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVkkmtakSVPADLSRPKSTSTSSM 379
Cdd:PHA03247  2756 RPAR-PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV------LAPAAALPPAASPAGPL 2828

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1862723050  380 KKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKP----SSTTPRLSRLA 434
Cdd:PHA03247  2829 PPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAakpaAPARPPVRRLA 2887
PHA03247 PHA03247
large tegument protein UL36; Provisional
 204-429 9.40e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 9.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  204 PPSPEKKTKPlattqPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAvASARPSILPSKDVKP 283
Cdd:PHA03247  2551 PPPPLPPAAP-----PAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPR-GPAPPSPLPPDTHAP 2624

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  284 KPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIktegkPAEVKKMTAKS 363
Cdd:PHA03247  2625 DPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAA-----RPTVGSLTSLA 2699

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1862723050  364 VPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKP--------TSAKPSSTTPR 429
Cdd:PHA03247  2700 DPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGParparpptTAGPPAPAPPA 2773
PHA03247 PHA03247
large tegument protein UL36; Provisional
 199-439 2.70e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 2.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  199 PNKELPPSPEKKT-KPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLA--SGLVPAAPPKRPAVASARPSi 275
Cdd:PHA03247  2556 PPAAPPAAPDRSVpPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAppSPLPPDTHAPDPPPPSPSPA- 2634

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  276 lPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAE 355
Cdd:PHA03247  2635 -ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPH 2713

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  356 VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLAT 435
Cdd:PHA03247  2714 ALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSE 2793


                   ....
gi 1862723050  436 NTSA 439
Cdd:PHA03247  2794 SRES 2797
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
186-440 3.12e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 47.15  E-value: 3.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 186 PVVSGTGnditTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTigglnkKPMSLASGLVPAAPPKR 265
Cdd:PRK07003  360 PAVTGGG----APGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAP------KAAAAAAATRAEAPPAA 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 266 PAVASA-----RPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLL 340
Cdd:PRK07003  430 PAPPATadrgdDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPD 509

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 341 PKKPTAIKTEGKPAEVKKMTAKSVPA------------------DLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKAT 402
Cdd:PRK07003  510 ARAPAAASREDAPAAAAPPAPEARPPtpaaaapaaraggaaaalDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAA 589

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1862723050 403 PMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 440
Cdd:PRK07003  590 PRVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPP 627
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 130-440 7.76e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.93  E-value: 7.76e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  130 EQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGIARPEEGRPVVSGTGNDITT----PPNKELPP 205
Cdd:PHA03307    30 DAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPaspaREGSPTPP 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  206 SPEKKTKPLATTQPAktstSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPA------------VASARP 273
Cdd:PHA03307   110 GPSSPDPPPPTPPPA----SPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAAssrqaalplsspEETARA 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  274 SILPSKDVKPKPIADAKAPEKRAsPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSR-------------SPSTLL 340
Cdd:PHA03307   186 PSSPPAEPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSgcgwgpenecplpRPAPIT 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  341 PKKPTAIKTEGKPAEVKKMTAKSVPADLSR-----------PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPS 409
Cdd:PHA03307   265 LPTRIWEASGWNGPSSRPGPASSSSSPRERspspspsspgsGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPG 344

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1862723050  410 TTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 440
Cdd:PHA03307   345 PSPSRSPSPSRPPPPADPSSPRKRPRPSRAP 375
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
237-428 2.07e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 44.46  E-value: 2.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 237 QPAPTTIGGlnkkpmslASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRsgskSTQT 316
Cdd:PRK07003  359 EPAVTGGGA--------PGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATR----AEAP 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 317 VAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEvkkmtAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVP 396
Cdd:PRK07003  427 PAAPAPPATADRGDDAADGDAPVPAKANARASADSRCDE-----RDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSA 501

                         170       180       190
                  ....*....|....*....|....*....|..
gi 1862723050 397 SRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP 428
Cdd:PRK07003  502 ATPAAVPDARAPAAASREDAPAAAAPPAPEAR 533
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 155-438 2.78e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.91  E-value: 2.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 155 PSSATADTSIFAGQNDPLKDSYgiARPEEGRPVVSGTGNDITTP-PNKELPPS--------PEKKTKPLATTQPAKTSTS 225
Cdd:PTZ00449  520 PPKAPGDKEGEEGEHEDSKESD--EPKEGGKPGETKEGEVGKKPgPAKEHKPSkiptlskkPEFPKDPKHPKDPEEPKKP 597

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 226 KAKTQPTSLPKQPAPttigglnKKPMSLAsglVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPA--- 302
Cdd:PTZ00449  598 KRPRSAQRPTRPKSP-------KLPELLD---IPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKppf 667

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 303 ------------SAPASRSGSKSTQTVAKTTTAAAVASTGPSS-----RSPSTLLPKKPTAIKTEGKPaeVKKMTAKSV- 364
Cdd:PTZ00449  668 dpkfkekfyddyLDAAAKSKETKTTVVLDESFESILKETLPETpgtpfTTPRPLPPKLPRDEEFPFEP--IGDPDAEQPd 745

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 365 PADLSRPKSTSTSSMKKTttlSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP------------RLSR 432
Cdd:PTZ00449  746 DIEFFTPPEEERTFFHET---PADTPLPDILAEEFKEEDIHAETGEPDEAMKRPDSPSEHEDKPpgdhpslpkkrhRLDG 822


                  ....*.
gi 1862723050 433 LATNTS 438
Cdd:PTZ00449  823 LALSTT 828
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 303-577 7.63e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.60  E-value: 7.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 303 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllpkkptaiKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 382
Cdd:pfam05109 459 TAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSP---------RDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTT 529

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 383 TTLSGTAPAAG-VVPSRVKATPMPSRPSTTPFIdkkpTSAKPSSTTPRLSRLATNT--SAPDLKNVRSKVGSTENIKHQP 459
Cdd:pfam05109 530 PTPNATSPTLGkTSPTSAVTTPTPNATSPTPAV----TTPTPNATIPTLGKTSPTSavTTPTPNATSPTVGETSPQANTT 605

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 460 GGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLC 539
Cdd:pfam05109 606 NHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVT 685

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1862723050 540 PGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGD 577
Cdd:pfam05109 686 PASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGE 723
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 262-423 1.62e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.60  E-value: 1.62e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 262 PPKRPAvASARPsilpskdvkPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS-----SRSP 336
Cdd:PTZ00449  510 PPEGPE-ASGLP---------PKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKP 579

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 337 StlLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL--SGTAPAAGVVPSRVKAtpmPSRPSTT--P 412
Cdd:PTZ00449  580 E--FPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRpeSPKSPKRPPPPQRPSS---PERPEGPkiI 654

                         170
                  ....*....|.
gi 1862723050 413 FIDKKPTSAKP 423
Cdd:PTZ00449  655 KSPKPPKSPKP 665
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 179-432 2.05e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.31  E-value: 2.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  179 ARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTK--------PLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKP 250
Cdd:PHA03307   133 DLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAassrqaalPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSP 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  251 MSLASGLVPAAPPKRPAV--ASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAaavaS 328
Cdd:PHA03307   213 ISASASSPAPAPGRSAADdaGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASS----S 288

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  329 TGPSSRSPSTLlPKKPTAIKTEGKPAEVKKMTAKSvPADLSRPKSTSTSSMKKTTTlSGTAPAAGVVPSRVKATPMPSRP 408
Cdd:PHA03307   289 SSPRERSPSPS-PSSPGSGPAPSSPRASSSSSSSR-ESSSSSTSSSSESSRGAAVS-PGPSPSRSPSPSRPPPPADPSSP 365

                          250       260
                   ....*....|....*....|....
gi 1862723050  409 STTPFIDKKPTSAKPSSTTPRLSR 432
Cdd:PHA03307   366 RKRPRPSRAPSSPAASAGRPTRRR 389
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 171-440 3.05e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 40.67  E-value: 3.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 171 PLKDSYGIARPEegrpVVSGTGNDITTPPNKELPPS--PEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNK 248
Cdd:pfam05109 432 PTLNTTGFAAPN----TTTGLPSSTHVPTNLTAPAStgPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMT 507

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 249 KPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVAS 328
Cdd:pfam05109 508 SPTSAVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPT 587

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 329 TGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTA--KSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRV--KATPM 404
Cdd:pfam05109 588 PNATSPTVGETSPQANTTNHTLGGTSSTPVVTSppKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSdnSTSHM 667

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1862723050 405 PSRPSTTPFIDKKPTSAKPSSTTPRlsRLATNTSAP 440
Cdd:pfam05109 668 PLLTSAHPTGGENITQVTPASTSTH--HVSTSSPAP 701
PHA03247 PHA03247
large tegument protein UL36; Provisional
 171-405 3.35e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 3.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  171 PLKDSYGIARPEEGRPVVSGTGNDITTPPNKELPPS--PEKKTKPLATTQPAKTSTSKAKTQPtSLPKQPAPTTIGGLNK 248
Cdd:PHA03247  2786 PAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAasPAGPLPPPTSAQPTAPPPPPGPPPP-SLPLGGSVAPGGDVRR 2864

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  249 KPMSLASGLVPAAPPKRPAVASARPSILPSKDV------------KPKPIADAKAPEKRASPSKPASAPASRSGSKSTQT 316
Cdd:PHA03247  2865 RPPSRSPAAKPAAPARPPVRRLARPAVSRSTESfalppdqperppQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLA 2944

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050  317 VAKTTTAAAVASTGPSSRSPSTLLPkkptaikteGKPAEVKKMTAKSVPadlSRPKSTSTSSMKKTTTLSGTAPAAGVVP 396
Cdd:PHA03247  2945 PTTDPAGAGEPSGAVPQPWLGALVP---------GRVAVPRFRVPQPAP---SREAPASSTPPLTGHSLSRVSSWASSLA 3012


                   ....*....
gi 1862723050  397 SRVKATPMP 405
Cdd:PHA03247  3013 LHEETDPPP 3021
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 151-440 5.01e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 39.90  E-value: 5.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 151 DLVFPSSATADTSIFAGQNDPlkdSYGIARPEEGRPVVSGTG--NDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAK 228
Cdd:pfam05109 505 DMTSPTSAVTTPTPNATSPTP---AVTTPTPNATSPTLGKTSptSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTS 581

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 229 TQPTSLPKQPAPT-------------TIGGLNKKPmslasglVPAAPPKRP--AVASARPSILPSK----DVKPKPIADA 289
Cdd:pfam05109 582 AVTTPTPNATSPTvgetspqanttnhTLGGTSSTP-------VVTSPPKNAtsAVTTGQHNITSSStssmSLRPSSISET 654

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 290 KAPEK--RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG-PSSRSPSTLLPKKPTAIKTEGKPAEV--------KK 358
Cdd:pfam05109 655 LSPSTsdNSTSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSsPAPRPGTTSQASGPGNSSTSTKPGEVnvtkgtppKN 734

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 359 MTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGV-VPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNT 437
Cdd:pfam05109 735 ATSPQAPSGQKTAVPTVTSTGGKANSTTGGKHTTGHgARTSTEPTTDYGGDSTTPRTRYNATTYLPPSTSSKLRPRWTFT 814


                  ...
gi 1862723050 438 SAP 440
Cdd:pfam05109 815 SPP 817
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
229-437 5.03e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.86  E-value: 5.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 229 TQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASR 308
Cdd:PRK12323  372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 309 SgskstQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGT 388
Cdd:PRK12323  452 P-----APAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESI 526

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1862723050 389 APAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNT 437
Cdd:PRK12323  527 PDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
PRK13808 PRK13808
adenylate kinase; Provisional
 211-352 8.51e-03

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 38.72  E-value: 8.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862723050 211 TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTtigglnKKPMSLASGLVPAAPPKRPAVASARPsilPSKDVKPKPIADAK 290
Cdd:PRK13808  199 AKKAAKTPAAKSGAKKASAKAKSAAKKVSKK------KAAKTAVSAKKAAKTAAKAAKKAKKT---AKKALKKAAKAVKK 269

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862723050 291 APEKraspSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 352
Cdd:PRK13808  270 AAKK----AAKAAAKAAKGAAKATKGKAKAKKKAGKKAAAGSKAKATAKAPKRGAKGKKAKK 327
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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