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Conserved domains on  [gi|1862412786|ref|NP_001371691|]
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microtubule-associated protein 4 isoform 127 [Homo sapiens]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 546-575 4.31e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 63.58  E-value: 4.31e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862412786 546 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 575
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 197-511 1.49e-11

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 68.04  E-value: 1.49e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  197 SPHSESFVSPEAVAEPPQPTAETVTGTGKKcslpaeedsvleKLGERKPCNSQPSELSSETSGiARPEEGRPVVSGTGND 276
Cdd:PHA03247  2632 SPAANEPDPHPPPTVPPPERPRDDPAPGRV------------SRPRRARRLGRAAQASSPPQR-PRRRAARPTVGSLTSL 2698

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  277 ITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAP--PKRPAVASAR 354
Cdd:PHA03247  2699 ADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTagPPAPAPPAAP 2775

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  355 PSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 434
Cdd:PHA03247  2776 AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGS 2855

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  435 PAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSST 508
Cdd:PHA03247  2856 VAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935


                   ...
gi 1862412786  509 TPR 511
Cdd:PHA03247  2936 PPR 2938
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 577-607 7.60e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 51.26  E-value: 7.60e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862412786 577 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 607
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 523-544 3.49e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 49.33  E-value: 3.49e-08
                          10        20
                  ....*....|....*....|..
gi 1862412786 523 DLKNVRSKVGSTENIKHQPGGG 544
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 546-575 4.31e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 63.58  E-value: 4.31e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862412786 546 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 575
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 197-511 1.49e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 68.04  E-value: 1.49e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  197 SPHSESFVSPEAVAEPPQPTAETVTGTGKKcslpaeedsvleKLGERKPCNSQPSELSSETSGiARPEEGRPVVSGTGND 276
Cdd:PHA03247  2632 SPAANEPDPHPPPTVPPPERPRDDPAPGRV------------SRPRRARRLGRAAQASSPPQR-PRRRAARPTVGSLTSL 2698

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  277 ITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAP--PKRPAVASAR 354
Cdd:PHA03247  2699 ADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTagPPAPAPPAAP 2775

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  355 PSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 434
Cdd:PHA03247  2776 AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGS 2855

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  435 PAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSST 508
Cdd:PHA03247  2856 VAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935


                   ...
gi 1862412786  509 TPR 511
Cdd:PHA03247  2936 PPR 2938
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 577-607 7.60e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 51.26  E-value: 7.60e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862412786 577 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 607
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 523-544 3.49e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 49.33  E-value: 3.49e-08
                          10        20
                  ....*....|....*....|..
gi 1862412786 523 DLKNVRSKVGSTENIKHQPGGG 544
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 257-522 3.18e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 40.67  E-value: 3.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 257 TSGIARPEegrpVVSGTGNDITTPPNKELPPS--PEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 334
Cdd:pfam05109 436 TTGFAAPN----TTTGLPSSTHVPTNLTAPAStgPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTS 511

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 335 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 414
Cdd:pfam05109 512 AVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNAT 591

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 415 SRSPSTLLPKKPTAIKTEGKPAEVKKMTA--KSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRV--KATPMPSRP 490
Cdd:pfam05109 592 SPTVGETSPQANTTNHTLGGTSSTPVVTSppKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSdnSTSHMPLLT 671

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1862412786 491 STTPFIDKKPTSAKPSSTTPRlsRLATNTSAP 522
Cdd:pfam05109 672 SAHPTGGENITQVTPASTSTH--HVSTSSPAP 701
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 546-575 4.31e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 63.58  E-value: 4.31e-13
                          10        20        30
                  ....*....|....*....|....*....|
gi 1862412786 546 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 575
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 197-511 1.49e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 68.04  E-value: 1.49e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  197 SPHSESFVSPEAVAEPPQPTAETVTGTGKKcslpaeedsvleKLGERKPCNSQPSELSSETSGiARPEEGRPVVSGTGND 276
Cdd:PHA03247  2632 SPAANEPDPHPPPTVPPPERPRDDPAPGRV------------SRPRRARRLGRAAQASSPPQR-PRRRAARPTVGSLTSL 2698

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  277 ITTPPNkelPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAP--PKRPAVASAR 354
Cdd:PHA03247  2699 ADPPPP---PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTagPPAPAPPAAP 2775

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  355 PSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 434
Cdd:PHA03247  2776 AAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGS 2855

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  435 PAE----VKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAA--GVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSST 508
Cdd:PHA03247  2856 VAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935


                   ...
gi 1862412786  509 TPR 511
Cdd:PHA03247  2936 PPR 2938
PHA03247 PHA03247
large tegument protein UL36; Provisional
 245-522 5.26e-11

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 66.50  E-value: 5.26e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  245 PCNSQPSELSSETSGIARPEEGRPVVSG--TGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAP 322
Cdd:PHA03247  2575 PRPSEPAVTSRARRPDAPPQSARPRAPVddRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRD 2654

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  323 TTIGG---LNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDvkpkpIADAKAPEKRASPSKPASAPASRSGSKSTQTV 399
Cdd:PHA03247  2655 DPAPGrvsRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTS-----LADPPPPPPTPEPAPHALVSATPLPPGPAAAR 2729

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  400 AKTTTAAAVASTGPSSRSPSTllPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTstssmkktttlsgtAPAAGVVPS 479
Cdd:PHA03247  2730 QASPALPAAPAPPAVPAGPAT--PGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT--------------RPAVASLSE 2793

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1862412786  480 RVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 522
Cdd:PHA03247  2794 SRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP 2836
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 577-607 7.60e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 51.26  E-value: 7.60e-09
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1862412786 577 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 607
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 523-544 3.49e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 49.33  E-value: 3.49e-08
                          10        20
                  ....*....|....*....|..
gi 1862412786 523 DLKNVRSKVGSTENIKHQPGGG 544
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 180-517 4.54e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 56.87  E-value: 4.54e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  180 PCNTAVVPQGWSVEALnsPHSESFVSPEAVAEPPQPTAEtvtgtgkkcslPAEEDSVLEKLGERKPCNSQPSELSSETSG 259
Cdd:PHA03247  2673 AAQASSPPQRPRRRAA--RPTVGSLTSLADPPPPPPTPE-----------PAPHALVSATPLPPGPAAARQASPALPAAP 2739

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  260 IARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTS----LPKQPAPTTIGGLNKKPmSL 335
Cdd:PHA03247  2740 APPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESReslpSPWDPADPPAAVLAPAA-AL 2818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  336 ASGLVPAAP-PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 414
Cdd:PHA03247  2819 PPAASPAGPlPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESF 2898

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  415 SRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADlsRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTP 494
Cdd:PHA03247  2899 ALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP--PPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPR 2976

                          330       340
                   ....*....|....*....|....*
gi 1862412786  495 FI--DKKPTSAKPSSTTPRLSRLAT 517
Cdd:PHA03247  2977 FRvpQPAPSREAPASSTPPLTGHSL 3001
PHA03247 PHA03247
large tegument protein UL36; Provisional
 213-516 9.19e-08

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 55.71  E-value: 9.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  213 PQPTAETVTGTGKKCSLPAEEDSVLEKLGERK--PCNSQPSELSSETSGIARPEEG---RPVVSGTGNDITTPPnkelPP 287
Cdd:PHA03247  2575 PRPSEPAVTSRARRPDAPPQSARPRAPVDDRGdpRGPAPPSPLPPDTHAPDPPPPSpspAANEPDPHPPPTVPP----PE 2650

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  288 SPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQP----APTTIGGLN---------KKPMSLASGLVPAAPPkrPAVASAR 354
Cdd:PHA03247  2651 RPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPrrraARPTVGSLTsladpppppPTPEPAPHALVSATPL--PPGPAAA 2728

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  355 PSILPSKDVKPKPIADAKAPEKRASPSKPASaPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 434
Cdd:PHA03247  2729 RQASPALPAAPAPPAVPAGPATPGGPARPAR-PPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADP 2807

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  435 PAEVkkmtakSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKP----SSTTP 510
Cdd:PHA03247  2808 PAAV------LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAakpaAPARP 2881


                   ....*.
gi 1862412786  511 RLSRLA 516
Cdd:PHA03247  2882 PVRRLA 2887
PHA03247 PHA03247
large tegument protein UL36; Provisional
 205-487 7.48e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 7.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  205 SPEAVAEPPQPTAETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTgndiTTPPNKE 284
Cdd:PHA03247  2759 RPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGP----LPPPTSA 2834

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  285 LPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLasglVPAAPPKRPAVASARPSILPSKDVK 364
Cdd:PHA03247  2835 QPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRR----LARPAVSRSTESFALPPDQPERPPQ 2910

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  365 PKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPkkptaikteGKPAEVKKMTAK 444
Cdd:PHA03247  2911 PQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP---------GRVAVPRFRVPQ 2981

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1862412786  445 SVPadlSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMP 487
Cdd:PHA03247  2982 PAP---SREAPASSTPPLTGHSLSRVSSWASSLALHEETDPPP 3021
PHA03247 PHA03247
large tegument protein UL36; Provisional
 286-511 2.31e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 2.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  286 PPSPEKKTKPlattqPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAvASARPSILPSKDVKP 365
Cdd:PHA03247  2551 PPPPLPPAAP-----PAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPR-GPAPPSPLPPDTHAP 2624

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  366 KPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIktegkPAEVKKMTAKS 445
Cdd:PHA03247  2625 DPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAA-----RPTVGSLTSLA 2699

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1862412786  446 VPADLSR---PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKP-----TSAKPSSTTPR 511
Cdd:PHA03247  2700 DPPPPPPtpePAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARParpptTAGPPAPAPPA 2773
PHA03247 PHA03247
large tegument protein UL36; Provisional
 252-529 2.47e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.01  E-value: 2.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  252 ELSSETSGIARPEEGrPVVSGTGNDITTPPNKELPPSPE-----KKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPttig 326
Cdd:PHA03247  2542 ELASDDAGDPPPPLP-PAAPPAAPDRSVPPPRPAPRPSEpavtsRARRPDAPPQSARPRAPVDDRGDPRGPAPPSP---- 2616

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  327 glnkkpmslasgLVPAAPPKRPAVASARPSilPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAA 406
Cdd:PHA03247  2617 ------------LPPDTHAPDPPPPSPSPA--ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQR 2682

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  407 AVASTGPSSRSPSTLLPKKPTAIKTegkPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVkaTPM 486
Cdd:PHA03247  2683 PRRRAARPTVGSLTSLADPPPPPPT---PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGP--ARP 2757

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1862412786  487 PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRS 529
Cdd:PHA03247  2758 ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS 2800
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 193-522 3.37e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.47  E-value: 3.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  193 EALNSPHSES---FVSPEAV-AEPPQPTAETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRP 268
Cdd:PHA03307    30 DAADDLLSGSqgqLVSDSAElAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPP 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  269 VVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTtiGGLNKKPMSLASGLVPAA----- 343
Cdd:PHA03307   110 GPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVAS--DAASSRQAALPLSSPEETaraps 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  344 PPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLP 423
Cdd:PHA03307   188 SPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPT 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  424 KKPTAIktEGKPAEVKKMTAKSVPADLSR-----------PKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 492
Cdd:PHA03307   268 RIWEAS--GWNGPSSRPGPASSSSSPRERspspspsspgsGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGP 345

                          330       340       350
                   ....*....|....*....|....*....|
gi 1862412786  493 TPFIDKKPTSAKPSSTTPRLSRLATNTSAP 522
Cdd:PHA03307   346 SPSRSPSPSRPPPPADPSSPRKRPRPSRAP 375
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
319-510 7.10e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.00  E-value: 7.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 319 QPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASAR-------PSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRS 391
Cdd:PRK07003  359 EPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASavpavtaVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADR 438

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 392 GSKSTQtvaktttaaavastgpssrSPSTLLPKKPTAIKTEGKPAEvkkmtAKSVPADLSRPKSTSTSSMKKTTTLSGTA 471
Cdd:PRK07003  439 GDDAAD-------------------GDAPVPAKANARASADSRCDE-----RDAQPPADSGSASAPASDAPPDAAFEPAP 494

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1862412786 472 PAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP 510
Cdd:PRK07003  495 RAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEAR 533
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 148-514 9.45e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.93  E-value: 9.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  148 DLADLVFPSSATADTSIFAGQNDPLKDSYGM-----SPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQP-TAETVT 221
Cdd:PHA03307    12 EAAAEGGEFFPRPPATPGDAADDLLSGSQGQlvsdsAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESrSTPTWS 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  222 GTGKKCSLPAEEDSVLEKLGERK--PCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTK----- 294
Cdd:PHA03307    92 LSTLAPASPAREGSPTPPGPSSPdpPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAassrq 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  295 ---PLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAV--ASARPSILPSKDVKPKPIA 369
Cdd:PHA03307   172 aalPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADdaGASSSDSSSSESSGCGWGP 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  370 DAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAaavaSTGPSSRSPSTLlPKKPTAIKTEGKPAEVKKMTAKSvPAD 449
Cdd:PHA03307   252 ENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASS----SSSPRERSPSPS-PSSPGSGPAPSSPRASSSSSSSR-ESS 325

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1862412786  450 LSRPKSTSTSSMKKTTTlSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSR 514
Cdd:PHA03307   326 SSSTSSSSESSRGAAVS-PGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRR 389
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
257-522 5.16e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 43.30  E-value: 5.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 257 TSGIARPEEGRPVVSGT--GNDITTPPNKELPPSPEKKTKPLATTQPA--KTSTSKAKTQPTSLPKQPAPTTIGGLNKKP 332
Cdd:PRK07003  363 TGGGAPGGGVPARVAGAvpAPGARAAAAVGASAVPAVTAVTGAAGAALapKAAAAAAATRAEAPPAAPAPPATADRGDDA 442

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 333 MSlasglVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTG 412
Cdd:PRK07003  443 AD-----GDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 413 PSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 492
Cdd:PRK07003  518 REDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVP 597

                         250       260       270
                  ....*....|....*....|....*....|
gi 1862412786 493 TPFIDKKPTSAKPSSTTPRLSRLATNTSAP 522
Cdd:PRK07003  598 TPRARAATGDAPPNGAARAEQAAESRGAPP 627
PHA03247 PHA03247
large tegument protein UL36; Provisional
 179-393 7.11e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 7.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  179 SPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSELSSETS 258
Cdd:PHA03247  2800 SPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPA 2879

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  259 GIARPEEGRPVVSGTGNDITTPPNK-ELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGglnKKPMSLAS 337
Cdd:PHA03247  2880 RPPVRRLARPAVSRSTESFALPPDQpERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTD---PAGAGEPS 2956

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1862412786  338 GLVPAapPKRPAVASARPSILPSKDVKPKPIADAKAPekraSPSKPASAPASRSGS 393
Cdd:PHA03247  2957 GAVPQ--PWLGALVPGRVAVPRFRVPQPAPSREAPAS----STPPLTGHSLSRVSS 3006
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 385-659 1.08e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 42.21  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 385 SAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTllpkkptaiKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKT 464
Cdd:pfam05109 459 TAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPSP---------RDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTT 529

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 465 TTLSGTAPAAG-VVPSRVKATPMPSRPSTTPFIdkkpTSAKPSSTTPRLSRLATNT--SAPDLKNVRSKVGSTENIKHQP 541
Cdd:pfam05109 530 PTPNATSPTLGkTSPTSAVTTPTPNATSPTPAV----TTPTPNATIPTLGKTSPTSavTTPTPNATSPTVGETSPQANTT 605

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 542 GGGRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLC 621
Cdd:pfam05109 606 NHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVT 685

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 1862412786 622 PGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGD 659
Cdd:pfam05109 686 PASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGE 723
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 344-505 1.47e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.98  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 344 PPKRPAvASARPsilpskdvkPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS-----SRSP 418
Cdd:PTZ00449  510 PPEGPE-ASGLP---------PKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKP 579

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 419 StlLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTL--SGTAPAAGVVPSRVKAtpmPSRPSTT--P 494
Cdd:PTZ00449  580 E--FPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRpeSPKSPKRPPPPQRPSS---PERPEGPkiI 654

                         170
                  ....*....|.
gi 1862412786 495 FIDKKPTSAKP 505
Cdd:PTZ00449  655 KSPKPPKSPKP 665
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 245-520 2.82e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.83  E-value: 2.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 245 PCNSQPSELSSETS-GIARPEEGRPVVSGTGNDITTPPNkelPPSPEKKTK-PLATTQPAKTSTSKAKTQPTS--LPKQP 320
Cdd:PTZ00449  524 PGDKEGEEGEHEDSkESDEPKEGGKPGETKEGEVGKKPG---PAKEHKPSKiPTLSKKPEFPKDPKHPKDPEEpkKPKRP 600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 321 APTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPA---------------S 385
Cdd:PTZ00449  601 RSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPKppfdpkfkekfyddyL 680

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 386 APASRSGSKSTQTVAKTTTAAAVASTGPSS-----RSPSTLLPKKPTAIKTEGKPaeVKKMTAKSV-PADLSRPKSTSTS 459
Cdd:PTZ00449  681 DAAAKSKETKTTVVLDESFESILKETLPETpgtpfTTPRPLPPKLPRDEEFPFEP--IGDPDAEQPdDIEFFTPPEEERT 758

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1862412786 460 SMKKTttlSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTP------------RLSRLATNTS 520
Cdd:PTZ00449  759 FFHET---PADTPLPDILAEEFKEEDIHAETGEPDEAMKRPDSPSEHEDKPpgdhpslpkkrhRLDGLALSTT 828
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 257-522 3.18e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 40.67  E-value: 3.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 257 TSGIARPEegrpVVSGTGNDITTPPNKELPPS--PEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMS 334
Cdd:pfam05109 436 TTGFAAPN----TTTGLPSSTHVPTNLTAPAStgPTVSTADVTSPTPAGTTSGASPVTPSPSPRDNGTESKAPDMTSPTS 511

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 335 LASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPS 414
Cdd:pfam05109 512 AVTTPTPNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNAT 591

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 415 SRSPSTLLPKKPTAIKTEGKPAEVKKMTA--KSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRV--KATPMPSRP 490
Cdd:pfam05109 592 SPTVGETSPQANTTNHTLGGTSSTPVVTSppKNATSAVTTGQHNITSSSTSSMSLRPSSISETLSPSTSdnSTSHMPLLT 671

                         250       260       270
                  ....*....|....*....|....*....|..
gi 1862412786 491 STTPFIDKKPTSAKPSSTTPRlsRLATNTSAP 522
Cdd:pfam05109 672 SAHPTGGENITQVTPASTSTH--HVSTSSPAP 701
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 179-522 4.43e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 40.28  E-value: 4.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 179 SPCNTAVVPQGWSVEA-LNSPHSESFVSPEAVAEPPQPtAETVTGTGKKCSLPAEEDSVLEklgerkpcnSQPSELSSET 257
Cdd:pfam05109 441 APNTTTGLPSSTHVPTnLTAPASTGPTVSTADVTSPTP-AGTTSGASPVTPSPSPRDNGTE---------SKAPDMTSPT 510

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 258 SGIARPEegrPVVSGTGNDITTP-PNKELP-------------PSPEKKTKPLATTQPAKTST--SKAKTQPTSLPKQPA 321
Cdd:pfam05109 511 SAVTTPT---PNATSPTPAVTTPtPNATSPtlgktsptsavttPTPNATSPTPAVTTPTPNATipTLGKTSPTSAVTTPT 587

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 322 PT----TIGGLNKKPMSL-------ASGLVPAAPPKRP--AVASARPSILPSK----DVKPKPIADAKAPEK--RASPSK 382
Cdd:pfam05109 588 PNatspTVGETSPQANTTnhtlggtSSTPVVTSPPKNAtsAVTTGQHNITSSStssmSLRPSSISETLSPSTsdNSTSHM 667

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 383 PASAPASRSGSKSTQTVAKTTTAAAVASTG-PSSRSPSTLLPKKPTAIKTEGKPAEV--------KKMTAKSVPADLSRP 453
Cdd:pfam05109 668 PLLTSAHPTGGENITQVTPASTSTHHVSTSsPAPRPGTTSQASGPGNSSTSTKPGEVnvtkgtppKNATSPQAPSGQKTA 747

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 454 KSTSTSSMKKTTTLSGTAPAAGV-VPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAP 522
Cdd:pfam05109 748 VPTVTSTGGKANSTTGGKHTTGHgARTSTEPTTDYGGDSTTPRTRYNATTYLPPSTSSKLRPRWTFTSPP 817
PRK13808 PRK13808
adenylate kinase; Provisional
 293-434 5.20e-03

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 39.49  E-value: 5.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 293 TKPLATTQPAKTSTSKAKTQPTSLPKQPAPTtigglnKKPMSLASGLVPAAPPKRPAVASARPsilPSKDVKPKPIADAK 372
Cdd:PRK13808  199 AKKAAKTPAAKSGAKKASAKAKSAAKKVSKK------KAAKTAVSAKKAAKTAAKAAKKAKKT---AKKALKKAAKAVKK 269

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1862412786 373 APEKraspSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGK 434
Cdd:PRK13808  270 AAKK----AAKAAAKAAKGAAKATKGKAKAKKKAGKKAAAGSKAKATAKAPKRGAKGKKAKK 327
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 191-436 5.42e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.15  E-value: 5.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  191 SVEALNSPHSESFVSPEAVAEPPQPTAETVT-GTGKKCSLPAEEDSVLEKLGeRKPCNSQPSELSSETSGiarPEEGRPV 269
Cdd:PHA03307   182 TARAPSSPPAEPPPSTPPAAASPRPPRRSSPiSASASSPAPAPGRSAADDAG-ASSSDSSSSESSGCGWG---PENECPL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  270 VSGTGNDITTPPNKELPPSPEKKTKPLATTQPAkTSTSKAKTQPTSLPKQPAPTTIGGLNK----KPMSLASGLVPAAPP 345
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWNGPSSRPGPASSSSS-PRERSPSPSPSSPGSGPAPSSPRASSSssssRESSSSSTSSSSESS 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786  346 KRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKK 425
Cdd:PHA03307   337 RGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSP 416

                          250
                   ....*....|.
gi 1862412786  426 PTAIKTEGKPA 436
Cdd:PHA03307   417 LDAGAASGAFY 427
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
311-519 5.70e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.86  E-value: 5.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 311 TQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASR 390
Cdd:PRK12323  372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1862412786 391 SgskstQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGT 470
Cdd:PRK12323  452 P-----APAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESI 526

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1862412786 471 APAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNT 519
Cdd:PRK12323  527 PDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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