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Conserved domains on  [gi|1845971717|ref|NP_001370970|]
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DUF38 domain-containing protein [Caenorhabditis elegans]

Protein Classification

FTH domain-containing protein( domain architecture ID 11976181)

FTH (FOG-2 homology) domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
263-409 3.57e-22

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


:

Pssm-ID: 396410  Cd Length: 141  Bit Score: 92.25  E-value: 3.57e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845971717 263 YIKCFEEFvLPLDRLLSVEKFKTM-LTNAQIVgQLLKYLDPVSLRKIEFgskyvnmetwkpWKHIKLDNTVNLCKMEHWK 341
Cdd:pfam01827   3 IIESFLNI-LKSKKCLHVKEISLSgLSFSEVA-SILPYFDAGTLEEIEL------------SSESDEDQFEEIVELEQWK 68
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1845971717 342 NAKELTIHNTVVKCN-LEVLIHFSKVDIILDSILLQDVVYLKDALLLSPTFRQFKAQFVNSDINET--IFD 409
Cdd:pfam01827  69 NAKSLKIEGSSLSSFpIEHLFHFEEFDIKLDSFSVEDAIKIRDILLKSSTFQSCTIRSPDLNPIEIakVFD 139
FTH super family cl28746
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
1-75 6.56e-09

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


The actual alignment was detected with superfamily member pfam01827:

Pssm-ID: 396410  Cd Length: 141  Bit Score: 54.50  E-value: 6.56e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1845971717   1 MDQWRNAKDIHLRNFFV-SIPFEHFSHCESAYIEVWKISADDIQKLIKVDFHAQDFRRIIVKYKSLEPDVTKKLLK 75
Cdd:pfam01827  64 LEQWKNAKSLKIEGSSLsSFPIEHLFHFEEFDIKLDSFSVEDAIKIRDILLKSSTFQSCTIRSPDLNPIEIAKVFD 139
 
Name Accession Description Interval E-value
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
263-409 3.57e-22

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


Pssm-ID: 396410  Cd Length: 141  Bit Score: 92.25  E-value: 3.57e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845971717 263 YIKCFEEFvLPLDRLLSVEKFKTM-LTNAQIVgQLLKYLDPVSLRKIEFgskyvnmetwkpWKHIKLDNTVNLCKMEHWK 341
Cdd:pfam01827   3 IIESFLNI-LKSKKCLHVKEISLSgLSFSEVA-SILPYFDAGTLEEIEL------------SSESDEDQFEEIVELEQWK 68
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1845971717 342 NAKELTIHNTVVKCN-LEVLIHFSKVDIILDSILLQDVVYLKDALLLSPTFRQFKAQFVNSDINET--IFD 409
Cdd:pfam01827  69 NAKSLKIEGSSLSSFpIEHLFHFEEFDIKLDSFSVEDAIKIRDILLKSSTFQSCTIRSPDLNPIEIakVFD 139
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
1-75 6.56e-09

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


Pssm-ID: 396410  Cd Length: 141  Bit Score: 54.50  E-value: 6.56e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1845971717   1 MDQWRNAKDIHLRNFFV-SIPFEHFSHCESAYIEVWKISADDIQKLIKVDFHAQDFRRIIVKYKSLEPDVTKKLLK 75
Cdd:pfam01827  64 LEQWKNAKSLKIEGSSLsSFPIEHLFHFEEFDIKLDSFSVEDAIKIRDILLKSSTFQSCTIRSPDLNPIEIAKVFD 139
 
Name Accession Description Interval E-value
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
263-409 3.57e-22

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


Pssm-ID: 396410  Cd Length: 141  Bit Score: 92.25  E-value: 3.57e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845971717 263 YIKCFEEFvLPLDRLLSVEKFKTM-LTNAQIVgQLLKYLDPVSLRKIEFgskyvnmetwkpWKHIKLDNTVNLCKMEHWK 341
Cdd:pfam01827   3 IIESFLNI-LKSKKCLHVKEISLSgLSFSEVA-SILPYFDAGTLEEIEL------------SSESDEDQFEEIVELEQWK 68
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1845971717 342 NAKELTIHNTVVKCN-LEVLIHFSKVDIILDSILLQDVVYLKDALLLSPTFRQFKAQFVNSDINET--IFD 409
Cdd:pfam01827  69 NAKSLKIEGSSLSSFpIEHLFHFEEFDIKLDSFSVEDAIKIRDILLKSSTFQSCTIRSPDLNPIEIakVFD 139
FTH pfam01827
FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is ...
1-75 6.56e-09

FTH domain; This presumed domain is likely to be a protein-protein interaction module. It is found in many proteins from C. elegans. The domain is found associated with the F-box pfam00646. This domain is named FTH after FOG-2 homology domain.


Pssm-ID: 396410  Cd Length: 141  Bit Score: 54.50  E-value: 6.56e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1845971717   1 MDQWRNAKDIHLRNFFV-SIPFEHFSHCESAYIEVWKISADDIQKLIKVDFHAQDFRRIIVKYKSLEPDVTKKLLK 75
Cdd:pfam01827  64 LEQWKNAKSLKIEGSSLsSFPIEHLFHFEEFDIKLDSFSVEDAIKIRDILLKSSTFQSCTIRSPDLNPIEIAKVFD 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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