|
Name |
Accession |
Description |
Interval |
E-value |
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
122-349 |
1.45e-09 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 62.36 E-value: 1.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 122 ANLRKNAAAAGTPPKQamqgasreqgnahQPTAGQIPQSSNQPAQQTHNVPRMpQPLQQVPhpSPVRG-SHPAAQQVQNA 200
Cdd:pfam09770 154 PDLQVDASLWGVAPKK-------------AAAPAPAPQPAAQPASLPAPSRKM-MSLEEVE--AAMRAqAKKPAQQPAPA 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 201 PQRIPQHVPMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHtGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQTPARGR 280
Cdd:pfam09770 218 PAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQ-GHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVP 296
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1845973955 281 PANAQLAQNAQQRNPQQVPMPQGvaphhippqalGPHGAAPQMTQQAPARGPSgaaqHAQNAHRMTHQQ 349
Cdd:pfam09770 297 VQPTQILQNPNRLSAARVGYPQN-----------PQPGVQPAPAHQAHRQQGS----FGRQAPIITHPQ 350
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
131-497 |
1.80e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 55.71 E-value: 1.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 131 AGTPPKQAMQGASREQGNAHQPTAGQIP----QSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQVQNAPQRIPQ 206
Cdd:PHA03247 2574 APRPSEPAVTSRARRPDAPPQSARPRAPvddrGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPR 2653
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 207 HVPMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPASRMAQQPVPlhqGVAPHQAAPQTIQQTPARGRPANAQL 286
Cdd:PHA03247 2654 DDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQ 2730
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 287 AQNAQQRNPQQVP------MPQGVAPHHIPPQALGPHGAAPQMTQQAPA-----RGPSGAAQHAQNAHRMTHQQVPLQAP 355
Cdd:PHA03247 2731 ASPALPAAPAPPAvpagpaTPGGPARPARPPTTAGPPAPAPPAAPAAGPprrltRPAVASLSESRESLPSPWDPADPPAA 2810
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 356 VQGPHRGAPQMAQ----QPGPHGAAQHPSSGTVAPMHITSLPGNH-----PLNRTHLlfNRQVVPALDIRNLIAQHRLMV 426
Cdd:PHA03247 2811 VLAPAAALPPAASpagpLPPPTSAQPTAPPPPPGPPPPSLPLGGSvapggDVRRRPP--SRSPAAKPAAPARPPVRRLAR 2888
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1845973955 427 DDFVRAQICYRLPENHQDYWPPGGHPIPMQQQQMRQGAGLPNMAMPPPPLMRHP-GPHQNPIHAMQSMQVQP 497
Cdd:PHA03247 2889 PAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPlAPTTDPAGAGEPSGAVP 2960
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
252-511 |
1.37e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 52.73 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 252 AQQPVP---LHQGVAPHQAAPQTIQQTPARGRPAnaQLAQNAQQRNPQQVPMPQ--------GVAPHHIPPQALGPH-GA 319
Cdd:pfam09770 104 RQQPAAraaQSSAQPPASSLPQYQYASQQSQQPS--KPVRTGYEKYKEPEPIPDlqvdaslwGVAPKKAAAPAPAPQpAA 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 320 AP------------------QMTQQAPARGPSGAAQHAQNAHRMTHQQVplQAPVQGPHRGAPQMAQQPGPHGAAQHPSS 381
Cdd:pfam09770 182 QPaslpapsrkmmsleeveaAMRAQAKKPAQQPAPAPAQPPAAPPAQQA--QQQQQFPPQIQQQQQPQQQPQQPQQHPGQ 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 382 GtvAPMHItslpgnhpLNRTHLLFNRQVVPALDIRNliaqhrlmvddfvraqicyrlPENHQDYWPPGGHPIPMQQQQMR 461
Cdd:pfam09770 260 G--HPVTI--------LQRPQSPQPDPAQPSIQPQA---------------------QQFHQQPPPVPVQPTQILQNPNR 308
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1845973955 462 QGAGLPNMAMPPPPlMRHPGPHQNPIHAMQSMQVQPPLS--PDQMnMQMFQQ 511
Cdd:pfam09770 309 LSAARVGYPQNPQP-GVQPAPAHQAHRQQGSFGRQAPIIthPQQL-AQLSEE 358
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
250-381 |
5.97e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 43.64 E-value: 5.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 250 RMAQQPVPLHQGVAPHQAAPQTIQQTPARGRPAnaqlaqnAQQRNPQQVpmpqgvaphhIPPQALGPHGAAPQMTQQAPA 329
Cdd:TIGR01628 367 RRAHLQDQFMQLQPRMRQLPMGSPMGGAMGQPP-------YYGQGPQQQ----------FNGQPLGWPRMSMMPTPMGPG 429
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1845973955 330 R--GPSGAAQHAQNAHRMTHQQVPLQAPVQGPHRGAPQMAQQPGPHGAAQHPSS 381
Cdd:TIGR01628 430 GplRPNGLAPMNAVRAPSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQST 483
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
46-513 |
9.68e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.54 E-value: 9.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 46 GTSSGGPSQAVSGASSGA---SMKTEPVARQVSTAQMKRDLEQAAV-YVPTP---IPEGSTQPQQRQQQQSQPQARQMST 118
Cdd:PRK10263 313 GAPITEPVAVAAAATTATqswAAPVEPVTQTPPVASVDVPPAQPTVaWQPVPgpqTGEPVIAPAPEGYPQQSQYAQPAVQ 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 119 QQAANLRKNAAAAGTPPKQAMQGASREQGNAHQPTAGQIPQSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQ-- 196
Cdd:PRK10263 393 YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQpa 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 197 VQNAPQRIPQHVPMPQGVAPHQVIQQVRA--PNIGASQMVQQAPSRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQ 274
Cdd:PRK10263 473 AQEPLYQQPQPVEQQPVVEPEPVVEETKParPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAV 552
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 275 TPARGRPANAQLAQNAQQRNPQQVPMPQGVAPHHIPPQALGP-----HGAAPQMTQQAPARGP----------------- 332
Cdd:PRK10263 553 PPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPrpqvkEGIGPQLPRPKRIRVPtrrelasygiklpsqra 632
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 333 --------------SGAAQHAQNAHRMTHQQVPLQAPVQGPHRGAPQMaQQPGPHGAAQHPSSGTV------APMHITSL 392
Cdd:PRK10263 633 aeekareaqrnqydSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQY-QHDVPVNAEDADAAAEAelarqfAQTQQQRY 711
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 393 PGNHPLNRTHL-LFNRQVVPALDIRNLIAQHRLMVDDFVRAQICYRLPENHQDYWPPGGHPIPMQQQQMRQgaglpnmaM 471
Cdd:PRK10263 712 SGEQPAGANPFsLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQ--------Q 783
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 1845973955 472 PPPPLMRHPGPHQNPIHAMQSMQVQPPLSPDQMNMQMFQQRA 513
Cdd:PRK10263 784 PVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVA 825
|
|
| SP2_N |
cd22540 |
N-terminal domain of transcription factor Specificity Protein (SP) 2; Specificity Proteins ... |
137-394 |
1.56e-03 |
|
N-terminal domain of transcription factor Specificity Protein (SP) 2; Specificity Proteins (SPs) are transcription factors that are involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. SP2 contains the least conserved DNA-binding domain within the SP subfamily of proteins, and its DNA sequence specificity differs from the other SP proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate, or in some cases, repress expression from different promoters. The transcription factor SP2 serves as a paradigm for indirect genomic binding. It does not require its DNA-binding domain for genomic DNA binding and occupies target promoters independently of whether they contain a cognate DNA-binding motif. SP2 belongs to a family of proteins, called the SP/Kruppel or Krueppel-like Factor (KLF) family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. SP factors preferentially bind GC boxes, while KLFs bind CACCC boxes. Another characteristic hallmark of SP factors is the presence of the Buttonhead (BTD) box CXCPXC, just N-terminal to the zinc fingers. The function of the BTD box is unknown, but it is thought to play an important physiological role. Another feature of most SP factors is the presence of a conserved amino acid stretch, the so-called SP box, located close to the N-terminus. SP factors may be separated into three groups based on their domain architecture and the similarity of their N-terminal transactivation domains: SP1-4, SP5, and SP6-9. The transactivation domains between the three groups are not homologous to one another. SP1-4 have similar N-terminal transactivation domains characterized by glutamine-rich regions, which, in most cases, have adjacent serine/threonine-rich regions. This model represents the N-terminal domain of SP2.
Pssm-ID: 411776 [Multi-domain] Cd Length: 511 Bit Score: 42.22 E-value: 1.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 137 QAMQGASREQGNAHQPTAGQIP------QSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQVQ----------NA 200
Cdd:cd22540 124 QQYQISPQIQAAGQINNSGQIQiipgtnQAIITPVQVLQQPQQAHKPVPIKPAPLQTSNTNSASLQVPgnviklqsggNV 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 201 PQRIPQHVPMPQGVAphQVIQQVRAPNIGASQMVQQAPSrghTGAAPASRMAQQP----VPLHQGVAPHQAAPQTIQQTP 276
Cdd:cd22540 204 ALTLPVNNLVGTQDG--ATQLQLAAAPSKPSKKIRKKSA---QAAQPAVTVAEQVetvlIETTADNIIQAGNNLLIVQSP 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 277 ARGRPANAQLAQNAQQRNPQQVPmpqgvaphHIPPQALgphgaapQMTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAPV 356
Cdd:cd22540 279 GTGQPAVLQQVQVLQPKQEQQVV--------QIPQQAL-------RVVQAASATLPTVPQKPLQNIQIQNSEPTPTQVYI 343
|
250 260 270
....*....|....*....|....*....|....*...
gi 1845973955 357 QGPHRGAPQMAQQPGPHGAAQHPSSGTVAPMHITSLPG 394
Cdd:cd22540 344 KTPSGEVQTVLLQEAPAATATPSSSTSTVQQQVTANNG 381
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
122-349 |
1.45e-09 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 62.36 E-value: 1.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 122 ANLRKNAAAAGTPPKQamqgasreqgnahQPTAGQIPQSSNQPAQQTHNVPRMpQPLQQVPhpSPVRG-SHPAAQQVQNA 200
Cdd:pfam09770 154 PDLQVDASLWGVAPKK-------------AAAPAPAPQPAAQPASLPAPSRKM-MSLEEVE--AAMRAqAKKPAQQPAPA 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 201 PQRIPQHVPMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHtGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQTPARGR 280
Cdd:pfam09770 218 PAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQ-GHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVP 296
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1845973955 281 PANAQLAQNAQQRNPQQVPMPQGvaphhippqalGPHGAAPQMTQQAPARGPSgaaqHAQNAHRMTHQQ 349
Cdd:pfam09770 297 VQPTQILQNPNRLSAARVGYPQN-----------PQPGVQPAPAHQAHRQQGS----FGRQAPIITHPQ 350
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
148-412 |
1.03e-08 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 59.66 E-value: 1.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 148 NAHQPTAGQIPQSSNQPAQQTHNVPRMPQPLQQVPhpSPVRGSHPAAQQvqnaPQRIPQHVPMPQ--GVAPHQVIQQVRA 225
Cdd:pfam09770 103 NRQQPAARAAQSSAQPPASSLPQYQYASQQSQQPS--KPVRTGYEKYKE----PEPIPDLQVDASlwGVAPKKAAAPAPA 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 226 PNIGASQMVQQAPSRghtgaapaSRMAQQPVplhqgvaphqaapqtiqqtpargrpaNAQLAQNAQQRNPQQVPMPQGV- 304
Cdd:pfam09770 177 PQPAAQPASLPAPSR--------KMMSLEEV--------------------------EAAMRAQAKKPAQQPAPAPAQPp 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 305 ----APHHIPPQALGPHGAAPQMTQQAPARGPsgaaQHAQNAHRMTHQQVPLQAPVQGphrgaPQMAQQPGPHGAAQHPS 380
Cdd:pfam09770 223 aappAQQAQQQQQFPPQIQQQQQPQQQPQQPQ----QHPGQGHPVTILQRPQSPQPDP-----AQPSIQPQAQQFHQQPP 293
|
250 260 270
....*....|....*....|....*....|....*.
gi 1845973955 381 SGTVAPMHITSLPGNHPLNR----THLLFNRQVVPA 412
Cdd:pfam09770 294 PVPVQPTQILQNPNRLSAARvgypQNPQPGVQPAPA 329
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
131-497 |
1.80e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 55.71 E-value: 1.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 131 AGTPPKQAMQGASREQGNAHQPTAGQIP----QSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQVQNAPQRIPQ 206
Cdd:PHA03247 2574 APRPSEPAVTSRARRPDAPPQSARPRAPvddrGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPR 2653
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 207 HVPMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPASRMAQQPVPlhqGVAPHQAAPQTIQQTPARGRPANAQL 286
Cdd:PHA03247 2654 DDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP---PPTPEPAPHALVSATPLPPGPAAARQ 2730
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 287 AQNAQQRNPQQVP------MPQGVAPHHIPPQALGPHGAAPQMTQQAPA-----RGPSGAAQHAQNAHRMTHQQVPLQAP 355
Cdd:PHA03247 2731 ASPALPAAPAPPAvpagpaTPGGPARPARPPTTAGPPAPAPPAAPAAGPprrltRPAVASLSESRESLPSPWDPADPPAA 2810
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 356 VQGPHRGAPQMAQ----QPGPHGAAQHPSSGTVAPMHITSLPGNH-----PLNRTHLlfNRQVVPALDIRNLIAQHRLMV 426
Cdd:PHA03247 2811 VLAPAAALPPAASpagpLPPPTSAQPTAPPPPPGPPPPSLPLGGSvapggDVRRRPP--SRSPAAKPAAPARPPVRRLAR 2888
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1845973955 427 DDFVRAQICYRLPENHQDYWPPGGHPIPMQQQQMRQGAGLPNMAMPPPPLMRHP-GPHQNPIHAMQSMQVQP 497
Cdd:PHA03247 2889 PAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPlAPTTDPAGAGEPSGAVP 2960
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
157-513 |
5.19e-07 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 53.86 E-value: 5.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 157 IPQSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQvQNAPQRIPQHVPMPQGVAPHQVIQQVRAPNIGASQMVQQ 236
Cdd:pfam09606 53 MSKKAAQQQQPQGGQGNGGMGGGQQGMPDPINALQNLAGQ-GTRPQMMGPMGPGPGGPMGQQMGGPGTASNLLASLGRPQ 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 237 APSRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQTPARGRPANAQLAQNAQQRNP-QQVPMPQGVAPHHIPPQALG 315
Cdd:pfam09606 132 MPMGGAGFPSQMSRVGRMQPGGQAGGMMQPSSGQPGSGTPNQMGPNGGPGQGQAGGMNGgQQGPMGGQMPPQMGVPGMPG 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 316 PHGAAPQMTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAPVQ-------------------------GPHRGAPQMAQQP 370
Cdd:pfam09606 212 PADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQqsqlgmginqmqqmpqgvgggagqgGPGQPMGPPGQQP 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 371 GPHGAAQHPSSGTVAPMHITSLP-----GNHPLNRThllfNRQVVPALDIRNLIAQHRLMVDDFVRAQICYRLPENHQDY 445
Cdd:pfam09606 292 GAMPNVMSIGDQNNYQQQQTRQQqqqqgGNHPAAHQ----QQMNQSVGQGGQVVALGGLNHLETWNPGNFGGLGANPMQR 367
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1845973955 446 WPPG--GHPIPMQQQQMRQGAglPNMAMPPPPLMRHPGPHQNPIHAMQSMQVQPPLSPDQMNM---QMFQQRA 513
Cdd:pfam09606 368 GQPGmmSSPSPVPGQQVRQVT--PNQFMRQSPQPSVPSPQGPGSQPPQSHPGGMIPSPALIPSpspQMSQQPA 438
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
252-511 |
1.37e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 52.73 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 252 AQQPVP---LHQGVAPHQAAPQTIQQTPARGRPAnaQLAQNAQQRNPQQVPMPQ--------GVAPHHIPPQALGPH-GA 319
Cdd:pfam09770 104 RQQPAAraaQSSAQPPASSLPQYQYASQQSQQPS--KPVRTGYEKYKEPEPIPDlqvdaslwGVAPKKAAAPAPAPQpAA 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 320 AP------------------QMTQQAPARGPSGAAQHAQNAHRMTHQQVplQAPVQGPHRGAPQMAQQPGPHGAAQHPSS 381
Cdd:pfam09770 182 QPaslpapsrkmmsleeveaAMRAQAKKPAQQPAPAPAQPPAAPPAQQA--QQQQQFPPQIQQQQQPQQQPQQPQQHPGQ 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 382 GtvAPMHItslpgnhpLNRTHLLFNRQVVPALDIRNliaqhrlmvddfvraqicyrlPENHQDYWPPGGHPIPMQQQQMR 461
Cdd:pfam09770 260 G--HPVTI--------LQRPQSPQPDPAQPSIQPQA---------------------QQFHQQPPPVPVQPTQILQNPNR 308
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1845973955 462 QGAGLPNMAMPPPPlMRHPGPHQNPIHAMQSMQVQPPLS--PDQMnMQMFQQ 511
Cdd:pfam09770 309 LSAARVGYPQNPQP-GVQPAPAHQAHRQQGSFGRQAPIIthPQQL-AQLSEE 358
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
129-367 |
2.00e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 51.91 E-value: 2.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 129 AAAGTPPKQAMQGASREQGNAHQPTAGQIPQSSNQPAQQThnvprmpqplqqvphpspvrgshPAAQQVQNAPQRIPQHV 208
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPA-----------------------APAPAGAAAAPAEASAA 642
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 209 PMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQTPARGRPANAQLAQ 288
Cdd:PRK07764 643 PAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPP 722
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 289 NAQQRNPQQVPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGPSGAAQHAQNAHRMTHQQVPL----QAPVQGPHRGAP 364
Cdd:PRK07764 723 QAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAeddaPSMDDEDRRDAE 802
|
...
gi 1845973955 365 QMA 367
Cdd:PRK07764 803 EVA 805
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
163-382 |
2.09e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 48.72 E-value: 2.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 163 QPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQVQNAPQRIPQHVPMPQGVAPhqviQQVRAPNIGASQMVQQAPSRGH 242
Cdd:PRK12323 364 RPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAAR----AVAAAPARRSPAPEALAAARQA 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 243 TGAAPASRMAQQPVPlhqgvAPHQAAPQTIQQTPARGRPANAQLAQNAQQRNPQQVPMPQGVAPHHIPPQALgphgAAPQ 322
Cdd:PRK12323 440 SARGPGGAPAPAPAP-----AAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEF----ASPA 510
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 323 MTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAPvQGPHRGAPQMAQQPGPHGAAQHPSSG 382
Cdd:PRK12323 511 PAQPDAAPAGWVAESIPDPATADPDDAFETLAP-APAAAPAPRAAAATEPVVAPRPPRAS 569
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
153-387 |
2.38e-05 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 48.54 E-value: 2.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 153 TAGQIPQSSNQPAQQTHNVPRMPQPLQQ-VPHPSPVRGSHPAAQQVQNAPQRIPQHVPMPQGVAPHQV-IQQVRAPNIGA 230
Cdd:PRK10263 328 TATQSWAAPVEPVTQTPPVASVDVPPAQpTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEpLQQPVQPQQPY 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 231 SQMVQQAPSRGHTGAAPASRMAQQPVPLHQgvaPHQAAPQTIQQTPARGRPANAQLAQNAQQrnPQQVPMPQgvAPHHIP 310
Cdd:PRK10263 408 YAPAAEQPAQQPYYAPAPEQPAQQPYYAPA---PEQPVAGNAWQAEEQQSTFAPQSTYQTEQ--TYQQPAAQ--EPLYQQ 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 311 PQALGPHGAA---PQMTQQAPARGPSGAAQHAQNAHRMTHQQV-----PLQAPVQGPhrgAPQMAQQPGPHGAAQHP--S 380
Cdd:PRK10263 481 PQPVEQQPVVepePVVEETKPARPPLYYFEEVEEKRAREREQLaawyqPIPEPVKEP---EPIKSSLKAPSVAAVPPveA 557
|
....*..
gi 1845973955 381 SGTVAPM 387
Cdd:PRK10263 558 AAAVSPL 564
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
45-387 |
6.25e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.29 E-value: 6.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 45 PGTSSGGPSQAVSGASSGASMKTEPVARQVSTAQmkrdleQAAVYVPTPIPEGSTQPQQRQQQQSQPQARQMSTQQAAnl 124
Cdd:PRK07764 393 APAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPA------AAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSA-- 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 125 RKNAAAAGTPPKQAMQGASREQGNAHQPTAGQIPQSSNQPAQQTHNVPRM--PQPLQQVP--------------HPSPVR 188
Cdd:PRK07764 465 QPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRErwPEILAAVPkrsrktwaillpeaTVLGVR 544
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 189 GSH-------PAAQQVQNAPQ---------------------RIPQHVPMPQGVAPHQVIQQVRAPNIGASQMVQQ--AP 238
Cdd:PRK07764 545 GDTlvlgfstGGLARRFASPGnaevlvtalaeelggdwqveaVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAApaAP 624
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 239 SRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQTPARGRPANAQLAQNAQQrnPQQVPMPQGVAPHHIPPQAlGPHG 318
Cdd:PRK07764 625 AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAP--AAPPPAPAPAAPAAPAGAA-PAQP 701
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 319 AAPQMTQQAPARGPSGAAQHAQNAH------RMTHQQVPL-----------QAPVQGPHRGAPQMAQQPGPHGAAQHPSS 381
Cdd:PRK07764 702 APAPAATPPAGQADDPAAQPPQAAQgasapsPAADDPVPLppepddppdpaGAPAQPPPPPAPAPAAAPAAAPPPSPPSE 781
|
....*.
gi 1845973955 382 GTVAPM 387
Cdd:PRK07764 782 EEEMAE 787
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
116-255 |
7.79e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 46.69 E-value: 7.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 116 MSTQQAANLRKNA--AAAGTPPKQAMQGASREQGNAHQPTAGQIPQSSNqpaQQTHNVPRMPQPlQQV--PHPSPVRGSH 191
Cdd:PRK14971 354 LTLIQLAQLTQKGddASGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSP---SQSSAAAQPSAP-QSAtqPAGTPPTVSV 429
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1845973955 192 PAAQQVQ-NAPQRIPQHVPMPQgVAPHQVIQQVRAPNIGAS-QMVQQAPSRGHTGAAPASRMAQQP 255
Cdd:PRK14971 430 DPPAAVPvNPPSTAPQAVRPAQ-FKEEKKIPVSKVSSLGPStLRPIQEKAEQATGNIKEAPTGTQK 494
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
134-291 |
1.05e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 46.25 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 134 PPKQAMQGASREQGNAHQPTAgQIPQSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQVQN--APQRIPQHVPMP 211
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEA-AAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAaaAPAAAPAAAPAA 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 212 QGVAPHQVIQqvrAPNIGASQMVQQAPSRGHTGAAPASRMAQQPVPL---HQGVAPHQAAPQTIQQTPARGrpANAQLAQ 288
Cdd:PRK14951 445 VALAPAPPAQ---AAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLtptEEGDVWHATVQQLAAAEAITA--LARELAL 519
|
...
gi 1845973955 289 NAQ 291
Cdd:PRK14951 520 QSE 522
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
237-380 |
1.92e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.75 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 237 APSRGHTGAAPASRMAQQPvplhqgvAPHQAAPQTIQQTPARGRPANAQLAqnAQQRNPQQVPMPQGVAPHHIPPQALGP 316
Cdd:PRK07764 380 RLERRLGVAGGAGAPAAAA-------PSAAAAAPAAAPAPAAAAPAAAAAP--APAAAPQPAPAPAPAPAPPSPAGNAPA 450
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1845973955 317 HGAAPQMTQQAPARGPSGAAQHAQnahrmthQQVPLQAPVQGPHRGAPQMAQQPGPHGAAQHPS 380
Cdd:PRK07764 451 GGAPSPPPAAAPSAQPAPAPAAAP-------EPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGAD 507
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
184-385 |
1.97e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 45.61 E-value: 1.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 184 PSPVRGSHPAAQQvqnaPQRIPQHVPMPQGVAPHQVIQQVRAPNIGASqmvqQAPSRGHTGAAPASRMAQQPVPLHQGVA 263
Cdd:PRK07003 360 PAVTGGGAPGGGV----PARVAGAVPAPGARAAAAVGASAVPAVTAVT----GAAGAALAPKAAAAAAATRAEAPPAAPA 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 264 PHQAAPQTiqqTPARGRPANAQLAQNAQQRnPQQVPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGPSGAAQHAQNAH 343
Cdd:PRK07003 432 PPATADRG---DDAADGDAPVPAKANARAS-ADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAV 507
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1845973955 344 RmthqqvPLQAPVQGPHRGAPQMAQQPGPHGAAQHPSSGTVA 385
Cdd:PRK07003 508 P------DARAPAAASREDAPAAAAPPAPEARPPTPAAAAPA 543
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
250-381 |
5.97e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 43.64 E-value: 5.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 250 RMAQQPVPLHQGVAPHQAAPQTIQQTPARGRPAnaqlaqnAQQRNPQQVpmpqgvaphhIPPQALGPHGAAPQMTQQAPA 329
Cdd:TIGR01628 367 RRAHLQDQFMQLQPRMRQLPMGSPMGGAMGQPP-------YYGQGPQQQ----------FNGQPLGWPRMSMMPTPMGPG 429
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1845973955 330 R--GPSGAAQHAQNAHRMTHQQVPLQAPVQGPHRGAPQMAQQPGPHGAAQHPSS 381
Cdd:TIGR01628 430 GplRPNGLAPMNAVRAPSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQST 483
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
261-388 |
7.51e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 43.55 E-value: 7.51e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 261 GVAPHQAAPQTIQQTPARGRPANAQLAQNAQQRNPQQVPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGPSGAAQHAQ 340
Cdd:PRK14951 369 AAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALA 448
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1845973955 341 NAHRMTHQQVPLQAPVQGPHRgaPQMAQQPGPHGAAQHPSSGTVAPMH 388
Cdd:PRK14951 449 PAPPAQAAPETVAIPVRVAPE--PAVASAAPAPAAAPAAARLTPTEEG 494
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
55-387 |
7.67e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.44 E-value: 7.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 55 AVSGASSGASMKTEPVARQVSTAqmkrdleqAAVYVPTPIPEGSTQPQQRQQQQSQPQARQmSTQQAANLRKNAAAAGTP 134
Cdd:PRK07764 366 SASDDERGLLARLERLERRLGVA--------GGAGAPAAAAPSAAAAAPAAAPAPAAAAPA-AAAAPAPAAAPQPAPAPA 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 135 PKQAMQGASREQGNAHQPTAGQIPQSSNQPAqqthNVPRMPQPLQQVPHPSPVRGSHPAaqqvqnAPQRIPQHVPMPQGV 214
Cdd:PRK07764 437 PAPAPPSPAGNAPAGGAPSPPPAAAPSAQPA----PAPAAAPEPTAAPAPAPPAAPAPA------AAPAAPAAPAAPAGA 506
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 215 APHQVIQQ------------------VRAPNIGASQMVQQAPSRGHTGAAPASRMAQQPVP------LHQ---------- 260
Cdd:PRK07764 507 DDAATLRErwpeilaavpkrsrktwaILLPEATVLGVRGDTLVLGFSTGGLARRFASPGNAevlvtaLAEelggdwqvea 586
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 261 GVAPHQAAPQTIQQTPARGRPANAQLAQNAQQRNP--QQVPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGPSGAAQH 338
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPaaPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGG 666
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1845973955 339 AQNAHRMTHQQVPLQAPVQ---GPHRGAPQMAQQPGPHGAAQHPSSGTVAPM 387
Cdd:PRK07764 667 DGWPAKAGGAAPAAPPPAPapaAPAAPAGAAPAQPAPAPAATPPAGQADDPA 718
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
46-513 |
9.68e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.54 E-value: 9.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 46 GTSSGGPSQAVSGASSGA---SMKTEPVARQVSTAQMKRDLEQAAV-YVPTP---IPEGSTQPQQRQQQQSQPQARQMST 118
Cdd:PRK10263 313 GAPITEPVAVAAAATTATqswAAPVEPVTQTPPVASVDVPPAQPTVaWQPVPgpqTGEPVIAPAPEGYPQQSQYAQPAVQ 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 119 QQAANLRKNAAAAGTPPKQAMQGASREQGNAHQPTAGQIPQSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQ-- 196
Cdd:PRK10263 393 YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQpa 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 197 VQNAPQRIPQHVPMPQGVAPHQVIQQVRA--PNIGASQMVQQAPSRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQ 274
Cdd:PRK10263 473 AQEPLYQQPQPVEQQPVVEPEPVVEETKParPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAV 552
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 275 TPARGRPANAQLAQNAQQRNPQQVPMPQGVAPHHIPPQALGP-----HGAAPQMTQQAPARGP----------------- 332
Cdd:PRK10263 553 PPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPrpqvkEGIGPQLPRPKRIRVPtrrelasygiklpsqra 632
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 333 --------------SGAAQHAQNAHRMTHQQVPLQAPVQGPHRGAPQMaQQPGPHGAAQHPSSGTV------APMHITSL 392
Cdd:PRK10263 633 aeekareaqrnqydSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQY-QHDVPVNAEDADAAAEAelarqfAQTQQQRY 711
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 393 PGNHPLNRTHL-LFNRQVVPALDIRNLIAQHRLMVDDFVRAQICYRLPENHQDYWPPGGHPIPMQQQQMRQgaglpnmaM 471
Cdd:PRK10263 712 SGEQPAGANPFsLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQ--------Q 783
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 1845973955 472 PPPPLMRHPGPHQNPIHAMQSMQVQPPLSPDQMNMQMFQQRA 513
Cdd:PRK10263 784 PVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVA 825
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
165-327 |
1.09e-03 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 42.87 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 165 AQQTHNVPRMPQPlqqvPHPSPVRGSHPAaqqvqnapqripqhvPMPQGVAPHQVIQQVRAPN-IGASQMVQQAPSRGHT 243
Cdd:TIGR01628 373 DQFMQLQPRMRQL----PMGSPMGGAMGQ---------------PPYYGQGPQQQFNGQPLGWpRMSMMPTPMGPGGPLR 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 244 GAAPASRMAQQPVPLHQGVAPHQAAPQTIQQTPargrpanaqlaQNAQQRNPQQVPMPQGVAPHHIPPQALGPHGAA--P 321
Cdd:TIGR01628 434 PNGLAPMNAVRAPSRNAQNAAQKPPMQPVMYPP-----------NYQSLPLSQDLPQPQSTASQGGQNKKLAQVLASatP 502
|
....*.
gi 1845973955 322 QMTQQA 327
Cdd:TIGR01628 503 QMQKQV 508
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
164-294 |
1.33e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 42.65 E-value: 1.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 164 PAQQTHNVPRMPQPlqqvpHPSPVRGSHPAAQQVQNAPQRIpqhvpmpqgvAPHQVIQQVRAPNIGASQMvqQAPSRGHT 243
Cdd:PRK06995 53 PPAAAAPAAAQPPP-----AAAPAAVSRPAAPAAEPAPWLV----------EHAKRLTAQREQLVARAAA--PAAPEAQA 115
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1845973955 244 GAAPASRMAQQPVPLHQGVAPhQAAPQTIQQTPARGRPANAQLAQNAQQRN 294
Cdd:PRK06995 116 PAAPAERAAAENAARRLARAA-AAAPRPRVPADAAAAVADAVKARIERIVN 165
|
|
| SP2_N |
cd22540 |
N-terminal domain of transcription factor Specificity Protein (SP) 2; Specificity Proteins ... |
137-394 |
1.56e-03 |
|
N-terminal domain of transcription factor Specificity Protein (SP) 2; Specificity Proteins (SPs) are transcription factors that are involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. SP2 contains the least conserved DNA-binding domain within the SP subfamily of proteins, and its DNA sequence specificity differs from the other SP proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate, or in some cases, repress expression from different promoters. The transcription factor SP2 serves as a paradigm for indirect genomic binding. It does not require its DNA-binding domain for genomic DNA binding and occupies target promoters independently of whether they contain a cognate DNA-binding motif. SP2 belongs to a family of proteins, called the SP/Kruppel or Krueppel-like Factor (KLF) family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. SP factors preferentially bind GC boxes, while KLFs bind CACCC boxes. Another characteristic hallmark of SP factors is the presence of the Buttonhead (BTD) box CXCPXC, just N-terminal to the zinc fingers. The function of the BTD box is unknown, but it is thought to play an important physiological role. Another feature of most SP factors is the presence of a conserved amino acid stretch, the so-called SP box, located close to the N-terminus. SP factors may be separated into three groups based on their domain architecture and the similarity of their N-terminal transactivation domains: SP1-4, SP5, and SP6-9. The transactivation domains between the three groups are not homologous to one another. SP1-4 have similar N-terminal transactivation domains characterized by glutamine-rich regions, which, in most cases, have adjacent serine/threonine-rich regions. This model represents the N-terminal domain of SP2.
Pssm-ID: 411776 [Multi-domain] Cd Length: 511 Bit Score: 42.22 E-value: 1.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 137 QAMQGASREQGNAHQPTAGQIP------QSSNQPAQQTHNVPRMPQPLQQVPHPSPVRGSHPAAQQVQ----------NA 200
Cdd:cd22540 124 QQYQISPQIQAAGQINNSGQIQiipgtnQAIITPVQVLQQPQQAHKPVPIKPAPLQTSNTNSASLQVPgnviklqsggNV 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 201 PQRIPQHVPMPQGVAphQVIQQVRAPNIGASQMVQQAPSrghTGAAPASRMAQQP----VPLHQGVAPHQAAPQTIQQTP 276
Cdd:cd22540 204 ALTLPVNNLVGTQDG--ATQLQLAAAPSKPSKKIRKKSA---QAAQPAVTVAEQVetvlIETTADNIIQAGNNLLIVQSP 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 277 ARGRPANAQLAQNAQQRNPQQVPmpqgvaphHIPPQALgphgaapQMTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAPV 356
Cdd:cd22540 279 GTGQPAVLQQVQVLQPKQEQQVV--------QIPQQAL-------RVVQAASATLPTVPQKPLQNIQIQNSEPTPTQVYI 343
|
250 260 270
....*....|....*....|....*....|....*...
gi 1845973955 357 QGPHRGAPQMAQQPGPHGAAQHPSSGTVAPMHITSLPG 394
Cdd:cd22540 344 KTPSGEVQTVLLQEAPAATATPSSSTSTVQQQVTANNG 381
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
116-271 |
1.65e-03 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 42.49 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 116 MSTQQAANLRKNAAAAGTPP----KQAMQGASREQGNahqptagqiPQSSNQPAQQTHNVPRMPQPLqqvPHPSPVRGsh 191
Cdd:TIGR01628 380 PRMRQLPMGSPMGGAMGQPPyygqGPQQQFNGQPLGW---------PRMSMMPTPMGPGGPLRPNGL---APMNAVRA-- 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 192 PAAQQVQNAPQRIPQHVPMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPASRMAQ----QPVPLHQGVAPHQA 267
Cdd:TIGR01628 446 PSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQNKKLAQVLASATPQMQKQvlgeRLFPLVEAIEPALA 525
|
....
gi 1845973955 268 APQT 271
Cdd:TIGR01628 526 AKIT 529
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
175-379 |
2.69e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 41.76 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 175 PQPLQQVPHPSPVRGSHPAAQQV--QNAPQRIPQHVPMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPASRMA 252
Cdd:PRK07003 374 ARVAGAVPAPGARAAAAVGASAVpaVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKA 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 253 QQPVPLHQGVAPHQAAPQTIQQT----------PARGRPANAQLAQNAQQRNPQQVPMPQGVAPHH---IPPQALGPHGA 319
Cdd:PRK07003 454 NARASADSRCDERDAQPPADSGSasapasdappDAAFEPAPRAAAPSAATPAAVPDARAPAAASREdapAAAAPPAPEAR 533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 320 APQMTQQAPAR------------------------GPSGAAQHAQNAHRMTHQQVPLQAPVQGPHRGAPQMAQQPGPHGA 375
Cdd:PRK07003 534 PPTPAAAAPAAraggaaaaldvlrnagmrvssdrgARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGA 613
|
....
gi 1845973955 376 AQHP 379
Cdd:PRK07003 614 ARAE 617
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
91-381 |
3.87e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 41.21 E-value: 3.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 91 PTPIPEGSTQPQQRQQQQSQPQARQMSTQQAANLRKNAAAAGTPPKQAMQGAS-REQGNAHQPTAGQIPQSSNQPAQQTH 169
Cdd:PHA03378 669 IGHIPYQPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATgRARPPAAAPGRARPPAAAPGRARPPA 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 170 NVPRMPQPLQQVPHPSPVRGSHPAAQqvqnAPQRIPQHVPMPQgvaphqviQQVRapnigASQMVQQAPSrghtgAAPAS 249
Cdd:PHA03378 749 AAPGRARPPAAAPGRARPPAAAPGAP----TPQPPPQAPPAPQ--------QRPR-----GAPTPQPPPQ-----AGPTS 806
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 250 RMAQQPVPLHQGVAPHQAAPQTIQQTPARGRPANAQLAQNAQQRNPQQVPMPQGVAPHHI------------PPQALGPH 317
Cdd:PHA03378 807 MQLMPRAAPGQQGPTKQILRQLLTGGVKRGRPSLKKPAALERQAAAGPTPSPGSGTSDKIvqapvfyppvlqPIQVMRQL 886
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1845973955 318 GAAPQMTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAPVQGPHRGAPQMaqqpgPHGAAQHPSS 381
Cdd:PHA03378 887 GSVRAAAASTVTQAPTEYTGERRGVGPMHPTDIPPSKRAKTDAYVESQP-----PHGGQSHSFS 945
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
147-385 |
4.22e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.01 E-value: 4.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 147 GNAHQPTAGQIPQSSNQPAQQTHNVPrMPQPLQQVPHPSPVRGSHPAAQQVQNAPQRipqhvpMPQGVAPHQVIQQVRAP 226
Cdd:PRK12323 370 GGAGPATAAAAPVAQPAPAAAAPAAA-APAPAAPPAAPAAAPAAAAAARAVAAAPAR------RSPAPEALAAARQASAR 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 227 NIGASQMVQQAPSRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQtiqqtparGRPANAQLAQNAQQRNPQQVPMPQGVAP 306
Cdd:PRK12323 443 GPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPA--------AAPAPADDDPPPWEELPPEFASPAPAQP 514
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 307 HHIPPQ---ALGPHGAAPQMTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAPVQGpHRGAPQMAQQPGPHGAAQHPSSGT 383
Cdd:PRK12323 515 DAAPAGwvaESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRAS-ASGLPDMFDGDWPALAARLPVRGL 593
|
..
gi 1845973955 384 VA 385
Cdd:PRK12323 594 AQ 595
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
199-501 |
4.43e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 41.29 E-value: 4.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 199 NAPQRIPQHVPmPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPASRMAQQPVPLHQ--GVAPHQAAPQTIQQTP 276
Cdd:pfam03154 161 SAQQQILQTQP-PVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTqsTAAPHTLIQQTPTLHP 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 277 ARGRPANAQLaqnaqQRNPQQVPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGP-SGAAQHAQNAHRMTHQQVPLQAP 355
Cdd:pfam03154 240 QRLPSPHPPL-----QPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPSHMQhPVPPQPFPLTPQSSQSQVPPGPS 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 356 VQGPHRgAPQMAQQPGPHGAAQHPSSGTVAPMHITSLPGNHPlnrthllfnrQVVPALDIRNLIAQHRLMVDDFVRAQIC 435
Cdd:pfam03154 315 PAAPGQ-SQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHI----------KPPPTTPIPQLPNPQSHKHPPHLSGPSP 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 436 YRLPEN------------HQDYWPPGGHPIPMqqQQMRQGAGLPNMAMPPPPLMRH-----PGPHQNPIHAMQSMQVQPP 498
Cdd:pfam03154 384 FQMNSNlppppalkplssLSTHHPPSAHPPPL--QLMPQSQQLPPPPAQPPVLTQSqslppPAASHPPTSGLHQVPSQSP 461
|
...
gi 1845973955 499 LSP 501
Cdd:pfam03154 462 FPQ 464
|
|
| PHA03160 |
PHA03160 |
hypothetical protein; Provisional |
285-405 |
5.45e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 165431 Cd Length: 499 Bit Score: 40.46 E-value: 5.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 285 QLAQNAQQR-NPQQVPMPQGVAPHHIPPQALGPHGAaPQMTQQAPargPSGAAQHAQNAHRMTHQQVPLQAPVQGPHRGA 363
Cdd:PHA03160 370 QAAINQPNRiIPHHFSNPYSFDPGHAPFFRYAPYGA-PKNDHHLL---PPLACSQQLPMQPLHVQQAPMQAPHVAPPPMQ 445
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 1845973955 364 PQMAQQP-------GPHGAAQHPSSGtvAPMHITSLPGNHPLNRTHLLF 405
Cdd:PHA03160 446 PPHVQQPrvlpstdGASNEAPKPSAQ--EPVHIDASFAQDPVSKIQKLF 492
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
145-232 |
5.48e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 40.84 E-value: 5.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 145 EQGNAHQPTAGQIPQSSNQPA--QQTHNVPRMP-QPLQQVPHPSPVRGSHPAAQQVQNAPQRIPQHVPMPQGVAPHQVIQ 221
Cdd:PRK10263 752 VQQPQQPVAPQQQYQQPQQPVapQPQYQQPQQPvAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQ 831
|
90
....*....|.
gi 1845973955 222 QVRAPNIGASQ 232
Cdd:PRK10263 832 QPQQPVAPQPQ 842
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
276-356 |
5.66e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 40.53 E-value: 5.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 276 PARGRPANAQLAQNAQQRNPQQvPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAP 355
Cdd:PRK14971 381 PVFTQPAAAPQPSAAAAASPSP-SQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRPAQFKEEKKIP 459
|
.
gi 1845973955 356 V 356
Cdd:PRK14971 460 V 460
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
126-295 |
7.56e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 40.23 E-value: 7.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 126 KNAAAAGTPPKQAMQGASREQGNAHQPTAGQIPQSSNQPAQQTHnvprMPQPLQQVPHPSPVRGSHPAAQQVQNAPQRIP 205
Cdd:PRK07994 362 AAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPAS----APQQAPAVPLPETTSQLLAARQQLQRAQGATK 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 206 QHVPMPQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQTIQQTPArgRPANAQ 285
Cdd:PRK07994 438 AKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKT--PELAAK 515
|
170
....*....|
gi 1845973955 286 LAQNAQQRNP 295
Cdd:PRK07994 516 LAAEAIERDP 525
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
216-376 |
7.96e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 40.23 E-value: 7.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 216 PHQVIQQVRAPnigasqmVQQAPSRGHTGAAPASRMAQQPVPLHQGVAPHQAAPQtiQQTPARGRPANAQLAQNAQQRNP 295
Cdd:PRK07994 361 PAAPLPEPEVP-------PQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQ--QAPAVPLPETTSQLLAARQQLQR 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 296 QQVPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGPSGAAQHAQNAHRMTHQQVPLQAPVQGPHRGAPQMA--QQPGPH 373
Cdd:PRK07994 432 AQGATKAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKAleHEKTPE 511
|
...
gi 1845973955 374 GAA 376
Cdd:PRK07994 512 LAA 514
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
211-342 |
9.13e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 40.14 E-value: 9.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 211 PQGVAPHQVIQQVRAPNIGASQMVQQAPSRGHTGAAPasrmaqqpvplhqgVAPHQAAPQTIQQTPARGRPANAQLAqNA 290
Cdd:PRK14971 375 PKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQP--------------SAPQSATQPAGTPPTVSVDPPAAVPV-NP 439
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1845973955 291 QQRNPQQVPMPQGVAPHHIPPQALGPHGAAPQMTQQAPARGPSGAAQHAQNA 342
Cdd:PRK14971 440 PSTAPQAVRPAQFKEEKKIPVSKVSSLGPSTLRPIQEKAEQATGNIKEAPTG 491
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
232-386 |
9.97e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 39.86 E-value: 9.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1845973955 232 QMVQQAPSRGHTGAAPASrmaqqpvplhqgvaphQAAPQTIQQTPARGRPANAQLAQNAQQRNPQQVPMPQGVAphhiPP 311
Cdd:PRK12323 359 RMLAFRPGQSGGGAGPAT----------------AAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAA----RA 418
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1845973955 312 QALGPHGAAPQMTQQAPARGPSGAAQHAQNAhrmthqqvPLQAPVQGPHRGAPQMAQQPGPHGAAQHPSSGTVAP 386
Cdd:PRK12323 419 VAAAPARRSPAPEALAAARQASARGPGGAPA--------PAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAP 485
|
|
| |
