DUF4440 domain-containing protein [Caenorhabditis elegans]
nuclear transport factor 2 family protein( domain architecture ID 233)
nuclear transport factor 2 (NTF2) family protein, similar to Aspergillus flavus scytalone dehydratases, Pseudomonas putida benzene 1,2-dioxygenase subunit beta, and many other members with similar structural details but divergent functions
List of domain hits
Name | Accession | Description | Interval | E-value | ||
NTF2_like super family | cl09109 | Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 ... |
34-97 | 2.17e-03 | ||
Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of divergent evolution wherein the proteins have many common structural details but diverge greatly in their function. For example, nuclear transport factor 2 (NTF2) mediates the nuclear import of RanGDP and binds to both RanGDP and FxFG repeat-containing nucleoporins while Ketosteroid isomerases catalyze the isomerization of delta-5-3-ketosteroid to delta-4-3-ketosteroid, by intramolecular transfer of the C4-beta proton to the C6-beta position. While the function of the beta sub-unit of the Ring hydroxylating dioxygenases is not known, Scytalone Dehydratases catalyzes two reactions in the biosynthetic pathway that produces fungal melanin. Members of the NTF2-like superfamily are widely distributed among bacteria, archaea and eukaryotes. The actual alignment was detected with superfamily member TIGR02246: Pssm-ID: 471850 Cd Length: 128 Bit Score: 35.82 E-value: 2.17e-03
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Name | Accession | Description | Interval | E-value | ||
TIGR02246 | TIGR02246 | conserved hypothetical protein; This family consists of uncharacterized proteins found in a ... |
34-97 | 2.17e-03 | ||
conserved hypothetical protein; This family consists of uncharacterized proteins found in a number of genera and species, including Streptomyces, Xanthomonas, Oceanobacillus iheyensis, Caulobacter crescentus CB15, and Xylella fastidiosa. The function is unknown. Pssm-ID: 274053 Cd Length: 128 Bit Score: 35.82 E-value: 2.17e-03
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Name | Accession | Description | Interval | E-value | ||
TIGR02246 | TIGR02246 | conserved hypothetical protein; This family consists of uncharacterized proteins found in a ... |
34-97 | 2.17e-03 | ||
conserved hypothetical protein; This family consists of uncharacterized proteins found in a number of genera and species, including Streptomyces, Xanthomonas, Oceanobacillus iheyensis, Caulobacter crescentus CB15, and Xylella fastidiosa. The function is unknown. Pssm-ID: 274053 Cd Length: 128 Bit Score: 35.82 E-value: 2.17e-03
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Blast search parameters | ||||
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