CXXC-type domain-containing protein [Caenorhabditis elegans]
Protein Classification
CXXC-type zinc finger protein( domain architecture ID 10488070)
CXXC-type zinc finger protein, such as human CXXC4 and CXXC5, contains eight conserved cysteine residues that bind to two zinc ions and plays important roles in epigenetic regulation by targeting various activities to CpG islands
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| zf-CXXC | pfam02008 | CXXC zinc finger domain; This domain contains eight conserved cysteine residues that bind to ... |
58-104 | 1.30e-12 | ||
CXXC zinc finger domain; This domain contains eight conserved cysteine residues that bind to two zinc ions. The CXXC domain is found in a variety of chromatin-associated proteins. This domain binds to nonmethyl-CpG dinucleotides. The domain is characterized by two repeats, and shows a peculiar internal duplication in which the second unit is inserted into the first one. Each of these units is characterized by four conserved cysteines, displaying a CXXCXXCX(n)C motif that chelate a Zn+2 ion. The DNA binding interface has been identified by NMR. In eukaryotes, the CXXC domain is found in stramenopiles, plants and metazoans. Plants possess a mono-CXXC domain that is present in distinct chromatin proteins. Structural comparisons show that the mono-CXXC is homologous to the structural-zinc binding domain of medium chain dehydrogenases. : Pssm-ID: 366873 Cd Length: 48 Bit Score: 61.99 E-value: 1.30e-12
|
||||||
| Name | Accession | Description | Interval | E-value | ||
| zf-CXXC | pfam02008 | CXXC zinc finger domain; This domain contains eight conserved cysteine residues that bind to ... |
58-104 | 1.30e-12 | ||
CXXC zinc finger domain; This domain contains eight conserved cysteine residues that bind to two zinc ions. The CXXC domain is found in a variety of chromatin-associated proteins. This domain binds to nonmethyl-CpG dinucleotides. The domain is characterized by two repeats, and shows a peculiar internal duplication in which the second unit is inserted into the first one. Each of these units is characterized by four conserved cysteines, displaying a CXXCXXCX(n)C motif that chelate a Zn+2 ion. The DNA binding interface has been identified by NMR. In eukaryotes, the CXXC domain is found in stramenopiles, plants and metazoans. Plants possess a mono-CXXC domain that is present in distinct chromatin proteins. Structural comparisons show that the mono-CXXC is homologous to the structural-zinc binding domain of medium chain dehydrogenases. Pssm-ID: 366873 Cd Length: 48 Bit Score: 61.99 E-value: 1.30e-12
|
||||||
| Name | Accession | Description | Interval | E-value | ||
| zf-CXXC | pfam02008 | CXXC zinc finger domain; This domain contains eight conserved cysteine residues that bind to ... |
58-104 | 1.30e-12 | ||
CXXC zinc finger domain; This domain contains eight conserved cysteine residues that bind to two zinc ions. The CXXC domain is found in a variety of chromatin-associated proteins. This domain binds to nonmethyl-CpG dinucleotides. The domain is characterized by two repeats, and shows a peculiar internal duplication in which the second unit is inserted into the first one. Each of these units is characterized by four conserved cysteines, displaying a CXXCXXCX(n)C motif that chelate a Zn+2 ion. The DNA binding interface has been identified by NMR. In eukaryotes, the CXXC domain is found in stramenopiles, plants and metazoans. Plants possess a mono-CXXC domain that is present in distinct chromatin proteins. Structural comparisons show that the mono-CXXC is homologous to the structural-zinc binding domain of medium chain dehydrogenases. Pssm-ID: 366873 Cd Length: 48 Bit Score: 61.99 E-value: 1.30e-12
|
||||||
| Blast search parameters | ||||
|
