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Conserved domains on  [gi|1831514779|ref|NP_001367161|]
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Protein BRICK1 [Caenorhabditis elegans]

Protein Classification

WASHC3/CCDC53 family protein( domain architecture ID 710795)

WASH complex subunit 3 (WASHC3)/coiled-coil domain-containing protein 53 (CCDC53) family protein similar to Drosophila melanogaster haematopoietic stem/progenitor cell protein 300 (HSPC300) playing a role in nervous system development

Gene Ontology:  GO:0030041|GO:0006887
PubMed:  20714399

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CCDC53 super family cl28766
Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key ...
32-66 6.58e-04

Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting.


The actual alignment was detected with superfamily member pfam10152:

Pssm-ID: 462967  Cd Length: 146  Bit Score: 35.34  E-value: 6.58e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1831514779  32 ANFLSSFELSCRTKLATLSDKLNLLERKVEFLEAR 66
Cdd:pfam10152   9 VQFLNRFSAVCEEKLVEVELRLQRLEATLAILEAK 43
 
Name Accession Description Interval E-value
CCDC53 pfam10152
Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key ...
32-66 6.58e-04

Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting.


Pssm-ID: 462967  Cd Length: 146  Bit Score: 35.34  E-value: 6.58e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1831514779  32 ANFLSSFELSCRTKLATLSDKLNLLERKVEFLEAR 66
Cdd:pfam10152   9 VQFLNRFSAVCEEKLVEVELRLQRLEATLAILEAK 43
 
Name Accession Description Interval E-value
CCDC53 pfam10152
Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key ...
32-66 6.58e-04

Subunit CCDC53 of WASH complex; CCDC53 is a component of the WASH complex, which plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting.


Pssm-ID: 462967  Cd Length: 146  Bit Score: 35.34  E-value: 6.58e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1831514779  32 ANFLSSFELSCRTKLATLSDKLNLLERKVEFLEAR 66
Cdd:pfam10152   9 VQFLNRFSAVCEEKLVEVELRLQRLEATLAILEAK 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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