NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1822188065|ref|NP_001365999|]
View 

mitochondrial adenyl nucleotide antiporter SLC25A23 isoform 5 [Mus musculus]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 66-339 6.88e-34

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 126.42  E-value: 6.88e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065  66 VAGAVAGAVSRTGTAPLDRLKVFMQVHAS----KSNRL----NILGGLRNMIQEGGVLSLWRGNGINVLKIAPESAIKFM 137
Cdd:PTZ00169   12 LMGGISAAISKTAVAPIERVKMLIQTQDSipeiKSGKVprysGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNFA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 138 AYEQIKRAI-RGQQETLHVQ---ERFVAGSLAGATAQTIIYPMEVLKTRLT--LRRTG--QYKGLLDCAKRILEREGPRA 209
Cdd:PTZ00169   92 FKDYFKNMFpKYNQKTDFWKffgVNILSGGLAGASSLLIVYPLDFARTRLAsdIGKGGdrEFTGLFDCLMKISKQTGFLS 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 210 FYRGYLPNVLGIIPYAGIDLAVYETLKNRWLQQYSHESAnpgILVLLGCGTISSTCGqIASYPLALVRTRMQAQASIEGG 289
Cdd:PTZ00169  172 LYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNI---LYKWAVAQTVTILAG-LISYPFDTVRRRMMMMSGRKAK 247

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1822188065 290 PQVSMVG---LLRHILSQEGVWGLYRGIAPNFMKVIPAvSISYVVYENMKQAL 339
Cdd:PTZ00169  248 SEIQYTGtldCWKKILKNEGLGGFFKGAWANVLRGAGG-ALVLVFYDELQKLL 299
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 66-339 6.88e-34

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 126.42  E-value: 6.88e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065  66 VAGAVAGAVSRTGTAPLDRLKVFMQVHAS----KSNRL----NILGGLRNMIQEGGVLSLWRGNGINVLKIAPESAIKFM 137
Cdd:PTZ00169   12 LMGGISAAISKTAVAPIERVKMLIQTQDSipeiKSGKVprysGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNFA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 138 AYEQIKRAI-RGQQETLHVQ---ERFVAGSLAGATAQTIIYPMEVLKTRLT--LRRTG--QYKGLLDCAKRILEREGPRA 209
Cdd:PTZ00169   92 FKDYFKNMFpKYNQKTDFWKffgVNILSGGLAGASSLLIVYPLDFARTRLAsdIGKGGdrEFTGLFDCLMKISKQTGFLS 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 210 FYRGYLPNVLGIIPYAGIDLAVYETLKNRWLQQYSHESAnpgILVLLGCGTISSTCGqIASYPLALVRTRMQAQASIEGG 289
Cdd:PTZ00169  172 LYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNI---LYKWAVAQTVTILAG-LISYPFDTVRRRMMMMSGRKAK 247

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1822188065 290 PQVSMVG---LLRHILSQEGVWGLYRGIAPNFMKVIPAvSISYVVYENMKQAL 339
Cdd:PTZ00169  248 SEIQYTGtldCWKKILKNEGLGGFFKGAWANVLRGAGG-ALVLVFYDELQKLL 299
Mito_carr pfam00153
Mitochondrial carrier protein;
151-244 1.04e-28

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 106.59  E-value: 1.04e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 151 ETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRT---GQYKGLLDCAKRILEREGPRAFYRGYLPNVLGIIPYAGI 227
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGsgkSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....*..
gi 1822188065 228 DLAVYETLKnRWLQQYS 244
Cdd:pfam00153  81 YFGTYETLK-RLLLKKL 96
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 66-339 6.88e-34

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 126.42  E-value: 6.88e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065  66 VAGAVAGAVSRTGTAPLDRLKVFMQVHAS----KSNRL----NILGGLRNMIQEGGVLSLWRGNGINVLKIAPESAIKFM 137
Cdd:PTZ00169   12 LMGGISAAISKTAVAPIERVKMLIQTQDSipeiKSGKVprysGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQAFNFA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 138 AYEQIKRAI-RGQQETLHVQ---ERFVAGSLAGATAQTIIYPMEVLKTRLT--LRRTG--QYKGLLDCAKRILEREGPRA 209
Cdd:PTZ00169   92 FKDYFKNMFpKYNQKTDFWKffgVNILSGGLAGASSLLIVYPLDFARTRLAsdIGKGGdrEFTGLFDCLMKISKQTGFLS 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 210 FYRGYLPNVLGIIPYAGIDLAVYETLKNRWLQQYSHESAnpgILVLLGCGTISSTCGqIASYPLALVRTRMQAQASIEGG 289
Cdd:PTZ00169  172 LYQGFGVSVQGIIVYRGAYFGLYDSAKALLFGNDKNTNI---LYKWAVAQTVTILAG-LISYPFDTVRRRMMMMSGRKAK 247

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1822188065 290 PQVSMVG---LLRHILSQEGVWGLYRGIAPNFMKVIPAvSISYVVYENMKQAL 339
Cdd:PTZ00169  248 SEIQYTGtldCWKKILKNEGLGGFFKGAWANVLRGAGG-ALVLVFYDELQKLL 299
Mito_carr pfam00153
Mitochondrial carrier protein;
151-244 1.04e-28

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 106.59  E-value: 1.04e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 151 ETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRT---GQYKGLLDCAKRILEREGPRAFYRGYLPNVLGIIPYAGI 227
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGsgkSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80

                          90
                  ....*....|....*..
gi 1822188065 228 DLAVYETLKnRWLQQYS 244
Cdd:pfam00153  81 YFGTYETLK-RLLLKKL 96
Mito_carr pfam00153
Mitochondrial carrier protein;
61-148 1.60e-25

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 98.11  E-value: 1.60e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065  61 WWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHA--SKSNRLNILGGLRNMIQEGGVLSLWRGNGINVLKIAPESAIKFMA 138
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGgsGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGT 84

                          90
                  ....*....|
gi 1822188065 139 YEQIKRAIRG 148
Cdd:pfam00153  85 YETLKRLLLK 94
Mito_carr pfam00153
Mitochondrial carrier protein;
250-340 4.55e-21

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 86.17  E-value: 4.55e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 250 PGILVLLGCGTISSTCGQIASYPLALVRTRMQAQASIEGGPQVSMVGLLRHILSQEGVWGLYRGIAPNFMKVIPAVSISY 329
Cdd:pfam00153   3 LSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYF 82

                          90
                  ....*....|.
gi 1822188065 330 VVYENMKQALG 340
Cdd:pfam00153  83 GTYETLKRLLL 93
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 61-219 4.98e-11

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 62.86  E-value: 4.98e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065  61 WWK----QLVAGAVAGAVSRTGTAPLD--RLKVFMQVHASKSNRLN-ILGGLRNMIQEGGVLSLWRGNGINVLKIAPESA 133
Cdd:PTZ00169  109 FWKffgvNILSGGLAGASSLLIVYPLDfaRTRLASDIGKGGDREFTgLFDCLMKISKQTGFLSLYQGFGVSVQGIIVYRG 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 134 IKFMAYEQIKRAIRGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTL---RRTG---QYKGLLDCAKRILEREGP 207
Cdd:PTZ00169  189 AYFGLYDSAKALLFGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRMMMmsgRKAKseiQYTGTLDCWKKILKNEGL 268

                         170
                  ....*....|..
gi 1822188065 208 RAFYRGYLPNVL 219
Cdd:PTZ00169  269 GGFFKGAWANVL 280
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 159-337 2.08e-08

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 54.55  E-value: 2.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 159 FVAGSLAGATAQTIIYPMEVLKTRLTlrrtgqykglldcAKRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYEtLKNR 238
Cdd:PTZ00168    7 LVTGALSGVIVDAVLYPIDSIKTNIQ-------------AKKSFSFSDIKKLYSGILPTLVGTVPASAFFYCFYE-LSKK 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 239 WLQQYsHESANPGILVLLGCgTISSTCGQIASYPLALVRTRMQAQASIeggpqvSMVGLLRHILSQEGVWgLYRGIAPNF 318
Cdd:PTZ00168   73 LLTEY-RENISKTNLYLIST-SIAEITACIVRLPFEIVKQNMQVSGNI------SVLKTIYEITQREGLP-SFLGKSYFV 143

                         170       180
                  ....*....|....*....|.
gi 1822188065 319 MKV--IPAVSISYVVYENMKQ 337
Cdd:PTZ00168  144 MIVreIPFDCIQYFLWETLKE 164
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 63-313 3.51e-07

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 50.69  E-value: 3.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065  63 KQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKSnrlniLGGLRNMIQegGVLSLWRGNginvlkiAPESAIKFMAYEQI 142
Cdd:PTZ00168    5 HNLVTGALSGVIVDAVLYPIDSIKTNIQAKKSFS-----FSDIKKLYS--GILPTLVGT-------VPASAFFYCFYELS 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 143 KRAIRGQQETLHVQERF-VAGSLAGATAQTIIYPMEVLKTRLtlrrtgQYKGLLDCAKRILE---REGPRAFY-RGYLPN 217
Cdd:PTZ00168   71 KKLLTEYRENISKTNLYlISTSIAEITACIVRLPFEIVKQNM------QVSGNISVLKTIYEitqREGLPSFLgKSYFVM 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1822188065 218 VLGIIPYAGIDLAVYETLKNRWLQQYSHESANPGILVLLGCGTISSTCGQIASYPLALVRTR--MQAQASIEGGPQVsmv 295
Cdd:PTZ00168  145 IVREIPFDCIQYFLWETLKEKAKKDFGKFSKKYPSITSAICGGLAGGIAGFLTTPVDVIKSRqiIYGKSYIETVTEI--- 221

                         250
                  ....*....|....*...
gi 1822188065 296 gllrhilSQEGVWGLYRG 313
Cdd:PTZ00168  222 -------AEEGYLTFYKG 232
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH