NCBI Conserved Domain Search

Conserved domains on [gi|1806646337|ref|NP_001365235|]

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myocardin isoform 3 [Homo sapiens]

Protein Classification

SAP domain-containing protein( domain architecture ID 10653801)

SAP (SAF-A/B, Acinus and PIAS) domain-containing protein may bind DNA or RNA and act as a transcriptional regulator

Graphical summary

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List of domain hits

Name

Accession

Description

Interval

E-value

SAP

pfam02037

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...

292-325

1.62e-08

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.

Pssm-ID: 460424 [Multi-domain] Cd Length: 35 Bit Score: 50.86 E-value: 1.62e-08

                          10        20        30
                  ....*....|....*....|....*....|....
gi 1806646337 292 LDDLKVSELRQQLRIRGLPVSGTKTALMDRLRPF 325
Cdd:pfam02037   1 LSKLTVAELKEELRKRGLPTSGKKAELIERLQEY 34

RPEL

smart00707

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;

27-52

1.18e-05

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;

Pssm-ID: 128947 Cd Length: 26 Bit Score: 42.46 E-value: 1.18e-05

                           10        20
                   ....*....|....*....|....*.
gi 1806646337   27 DDLNEKIALRPGPLELVEKNILPVDS 52
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26

Name

Accession

Description

Interval

E-value

SAP

pfam02037

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...

292-325

1.62e-08

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.

Pssm-ID: 460424 [Multi-domain] Cd Length: 35 Bit Score: 50.86 E-value: 1.62e-08

                          10        20        30
                  ....*....|....*....|....*....|....
gi 1806646337 292 LDDLKVSELRQQLRIRGLPVSGTKTALMDRLRPF 325
Cdd:pfam02037   1 LSKLTVAELKEELRKRGLPTSGKKAELIERLQEY 34

SAP

smart00513

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;

292-323

1.98e-08

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;

Pssm-ID: 128789 [Multi-domain] Cd Length: 35 Bit Score: 50.56 E-value: 1.98e-08

                           10        20        30
                   ....*....|....*....|....*....|..
gi 1806646337  292 LDDLKVSELRQQLRIRGLPVSGTKTALMDRLR 323
Cdd:smart00513   1 LAKLKVSELKDELKKRGLSTSGTKAELVDRLL 32

RPEL

smart00707

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;

27-52

1.18e-05

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;

Pssm-ID: 128947 Cd Length: 26 Bit Score: 42.46 E-value: 1.18e-05

                           10        20
                   ....*....|....*....|....*.
gi 1806646337   27 DDLNEKIALRPGPLELVEKNILPVDS 52
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26

RPEL

pfam02755

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...

28-51

2.93e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.

Pssm-ID: 460677 Cd Length: 24 Bit Score: 41.49 E-value: 2.93e-05

                          10        20
                  ....*....|....*....|....
gi 1806646337  28 DLNEKIALRPGPLELVEKNILPVD 51
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPED 24

Name

Accession

Description

Interval

E-value

SAP

pfam02037

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...

292-325

1.62e-08

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.

Pssm-ID: 460424 [Multi-domain] Cd Length: 35 Bit Score: 50.86 E-value: 1.62e-08

                          10        20        30
                  ....*....|....*....|....*....|....
gi 1806646337 292 LDDLKVSELRQQLRIRGLPVSGTKTALMDRLRPF 325
Cdd:pfam02037   1 LSKLTVAELKEELRKRGLPTSGKKAELIERLQEY 34

SAP

smart00513

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;

292-323

1.98e-08

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;

Pssm-ID: 128789 [Multi-domain] Cd Length: 35 Bit Score: 50.56 E-value: 1.98e-08

                           10        20        30
                   ....*....|....*....|....*....|..
gi 1806646337  292 LDDLKVSELRQQLRIRGLPVSGTKTALMDRLR 323
Cdd:smart00513   1 LAKLKVSELKDELKKRGLSTSGTKAELVDRLL 32

RPEL

smart00707

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;

27-52

1.18e-05

Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2;

Pssm-ID: 128947 Cd Length: 26 Bit Score: 42.46 E-value: 1.18e-05

                           10        20
                   ....*....|....*....|....*.
gi 1806646337   27 DDLNEKIALRPGPLELVEKNILPVDS 52
Cdd:smart00707   1 DVLNRKLSQRPTREELEERNILKELS 26

RPEL

pfam02755

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL ...

28-51

2.93e-05

RPEL repeat; The RPEL repeat is named after four conserved amino acids it contains. The RPEL motif binds to actin.

Pssm-ID: 460677 Cd Length: 24 Bit Score: 41.49 E-value: 2.93e-05

                          10        20
                  ....*....|....*....|....
gi 1806646337  28 DLNEKIALRPGPLELVEKNILPVD 51
Cdd:pfam02755   1 SLERKLSHRPTREELVERNILPED 24

Blast search parameters

Data Source:	Precalculated data, version = cdd.v.3.21
Preset Options:	Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01