microtubule-associated protein 2 isoform 20 [Homo sapiens]
List of domain hits
Name | Accession | Description | Interval | E-value | |||||
MAP2_projctn super family | cl25763 | MAP2/Tau projection domain; This domain is found in the MAP2/Tau family of proteins which ... |
151-263 | 3.08e-67 | |||||
MAP2/Tau projection domain; This domain is found in the MAP2/Tau family of proteins which includes MAP2, MAP4, Tau, and their homologs. All isoforms contain a conserved C-terminal domain containing tubulin-binding repeats (pfam00418), and a N-terminal projection domain of varying size. This domain has a net negative charge and exerts a long-range repulsive force. This provides a mechanism that can regulate microtubule spacing which might facilitate efficient organelle transport. The actual alignment was detected with superfamily member pfam08377: Pssm-ID: 429957 [Multi-domain] Cd Length: 1134 Bit Score: 236.86 E-value: 3.08e-67
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Tubulin-binding | pfam00418 | Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
450-479 | 7.50e-12 | |||||
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif. : Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 59.73 E-value: 7.50e-12
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Tubulin-binding | pfam00418 | Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
481-511 | 2.64e-11 | |||||
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif. : Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 58.19 E-value: 2.64e-11
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Tubulin-binding | pfam00418 | Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
419-448 | 3.06e-07 | |||||
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif. : Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 46.64 E-value: 3.06e-07
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PTZ00449 super family | cl33186 | 104 kDa microneme/rhoptry antigen; Provisional |
206-446 | 2.28e-04 | |||||
104 kDa microneme/rhoptry antigen; Provisional The actual alignment was detected with superfamily member PTZ00449: Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 44.30 E-value: 2.28e-04
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Name | Accession | Description | Interval | E-value | |||||
MAP2_projctn | pfam08377 | MAP2/Tau projection domain; This domain is found in the MAP2/Tau family of proteins which ... |
151-263 | 3.08e-67 | |||||
MAP2/Tau projection domain; This domain is found in the MAP2/Tau family of proteins which includes MAP2, MAP4, Tau, and their homologs. All isoforms contain a conserved C-terminal domain containing tubulin-binding repeats (pfam00418), and a N-terminal projection domain of varying size. This domain has a net negative charge and exerts a long-range repulsive force. This provides a mechanism that can regulate microtubule spacing which might facilitate efficient organelle transport. Pssm-ID: 429957 [Multi-domain] Cd Length: 1134 Bit Score: 236.86 E-value: 3.08e-67
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Tubulin-binding | pfam00418 | Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
450-479 | 7.50e-12 | |||||
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif. Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 59.73 E-value: 7.50e-12
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Tubulin-binding | pfam00418 | Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
481-511 | 2.64e-11 | |||||
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif. Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 58.19 E-value: 2.64e-11
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Tubulin-binding | pfam00418 | Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
419-448 | 3.06e-07 | |||||
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif. Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 46.64 E-value: 3.06e-07
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PTZ00449 | PTZ00449 | 104 kDa microneme/rhoptry antigen; Provisional |
206-446 | 2.28e-04 | |||||
104 kDa microneme/rhoptry antigen; Provisional Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 44.30 E-value: 2.28e-04
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Name | Accession | Description | Interval | E-value | |||||
MAP2_projctn | pfam08377 | MAP2/Tau projection domain; This domain is found in the MAP2/Tau family of proteins which ... |
151-263 | 3.08e-67 | |||||
MAP2/Tau projection domain; This domain is found in the MAP2/Tau family of proteins which includes MAP2, MAP4, Tau, and their homologs. All isoforms contain a conserved C-terminal domain containing tubulin-binding repeats (pfam00418), and a N-terminal projection domain of varying size. This domain has a net negative charge and exerts a long-range repulsive force. This provides a mechanism that can regulate microtubule spacing which might facilitate efficient organelle transport. Pssm-ID: 429957 [Multi-domain] Cd Length: 1134 Bit Score: 236.86 E-value: 3.08e-67
|
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Tubulin-binding | pfam00418 | Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
450-479 | 7.50e-12 | |||||
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif. Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 59.73 E-value: 7.50e-12
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Tubulin-binding | pfam00418 | Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
481-511 | 2.64e-11 | |||||
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif. Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 58.19 E-value: 2.64e-11
|
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Tubulin-binding | pfam00418 | Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ... |
419-448 | 3.06e-07 | |||||
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif. Pssm-ID: 459807 [Multi-domain] Cd Length: 30 Bit Score: 46.64 E-value: 3.06e-07
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PTZ00449 | PTZ00449 | 104 kDa microneme/rhoptry antigen; Provisional |
206-446 | 2.28e-04 | |||||
104 kDa microneme/rhoptry antigen; Provisional Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 44.30 E-value: 2.28e-04
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Blast search parameters | ||||
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