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Conserved domains on  [gi|1735137167|ref|NP_001360870|]
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tetratricopeptide repeat protein 13 isoform 7 precursor [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
155-272 2.54e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 93.92  E-value: 2.54e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 234
Cdd:COG0457    24 YEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKAL 103

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1735137167 235 QLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 272
Cdd:COG0457   104 ELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDP 141
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
155-272 2.54e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 93.92  E-value: 2.54e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 234
Cdd:COG0457    24 YEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKAL 103

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1735137167 235 QLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 272
Cdd:COG0457   104 ELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDP 141
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 174-260 1.17e-08

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 57.25  E-value: 1.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 174 DAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKglshva 253
Cdd:cd24142     1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEKYLY------ 74


                  ....*..
gi 1735137167 254 MGQFYEG 260
Cdd:cd24142    75 LGQLSGG 81
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 104-288 1.17e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 1.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 104 EKILSQAKSIAEQkrfpfatdndSTNEELAIAYVLVGSGLYDEAirhfstmlQEAIEafkEALKQKVDFIDAYKSLGQAY 183
Cdd:TIGR02917 145 QKSYEQALAIDPR----------SLYAKLGLAQLALAENRFDEA--------RALID---EVLTADPGNVDALLLKGDLL 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 184 RELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKA 263
Cdd:TIGR02917 204 LSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARET 283

                         170       180
                  ....*....|....*....|....*
gi 1735137167 264 QTKVMlndplpgqKASPEYLRVKYL 288
Cdd:TIGR02917 284 LQDAL--------KSAPEYLPALLL 300
PRK11189 PRK11189
lipoprotein NlpI; Provisional
 162-238 2.26e-07

lipoprotein NlpI; Provisional


Pssm-ID: 236875 [Multi-domain]  Cd Length: 296  Bit Score: 52.97  E-value: 2.26e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1735137167 162 FKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 238
Cdd:PRK11189   87 FSQALALRPDMADAYNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAYLNRGIALYYGGRYELAQDDLLAFYQDDP 163
TPR_1 pfam00515
Tetratricopeptide repeat;
173-206 9.86e-07

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 45.49  E-value: 9.86e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1735137167 173 IDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 206
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 173-206 1.83e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 44.74  E-value: 1.83e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1735137167  173 IDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 206
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
155-272 2.54e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 93.92  E-value: 2.54e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 234
Cdd:COG0457    24 YEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKAL 103

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1735137167 235 QLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 272
Cdd:COG0457   104 ELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDP 141
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
134-263 5.33e-21

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 92.76  E-value: 5.33e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 134 IAYVLVGSGLYDEAIRHFSTML-----------------------QEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFD 190
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKALeldpddaealynlglaylrlgryEEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1735137167 191 AATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKA 263
Cdd:COG0457    94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALEL 166
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 157-263 2.27e-18

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 81.59  E-value: 2.27e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 157 EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQL 236
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100
                  ....*....|....*....|....*..
gi 1735137167 237 EPYNEVCQYMKGLSHVAMGQFYEGIKA 263
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAA 107
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 137-272 3.54e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 82.47  E-value: 3.54e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 137 VLVGSGLYDEAIRHFSTM-LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGM 215
Cdd:COG2956     5 VAAALGWYFKGLNYLLNGqPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQ 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1735137167 216 MLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 272
Cdd:COG2956    85 DYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGP 141
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 155-263 3.92e-17

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 85.43  E-value: 3.92e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 234
Cdd:COG3914    94 YEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRAL 173

                          90       100
                  ....*....|....*....|....*....
gi 1735137167 235 QLEPYNEVCQYMKGLSHVAMGQFYEGIKA 263
Cdd:COG3914   174 ELDPDNAEALNNLGNALQDLGRLEEAIAA 202
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
166-272 5.03e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 81.21  E-value: 5.03e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 166 LKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQY 245
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90       100
                  ....*....|....*....|....*..
gi 1735137167 246 MKGLSHVAMGQFYEGIKAQTKVMLNDP 272
Cdd:COG0457    81 NLGLALQALGRYEEALEDYDKALELDP 107
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 155-272 5.12e-17

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 78.31  E-value: 5.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 234
Cdd:COG4783    20 YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1735137167 235 QLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 272
Cdd:COG4783   100 KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 129-272 5.23e-17

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 85.04  E-value: 5.23e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 129 NEELAIAYVLVGSGLYDEAirhfstMLQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQ 208
Cdd:COG3914   108 NPDNAEALFNLGNLLLALG------RLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAE 181

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1735137167 209 TLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEV--CQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 272
Cdd:COG3914   182 ALNNLGNALQDLGRLEEAIAAYRRALELDPDNADahSNLLFALRQACDWEVYDRFEELLAALARGP 247
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 155-238 1.07e-15

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 74.27  E-value: 1.07e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 234
Cdd:COG4235    33 YDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL 112


                  ....
gi 1735137167 235 QLEP 238
Cdd:COG4235   113 ALLP 116
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 124-272 1.39e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 77.46  E-value: 1.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 124 DNDSTNEELAIAYVLvgSGLYDEAIRHFSTML-----------------------QEAIEAFKEALKQKVDFIDAYKSLG 180
Cdd:COG2956    74 DRAEALLELAQDYLK--AGLLDRAEELLEKLLeldpddaealrllaeiyeqegdwEKAIEVLERLLKLGPENAHAYCELA 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 181 QAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEG 260
Cdd:COG2956   152 ELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEA 231

                         170
                  ....*....|..
gi 1735137167 261 IKAQTKVMLNDP 272
Cdd:COG2956   232 LELLRKALELDP 243
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
133-307 5.33e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.43  E-value: 5.33e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 133 AIAYVLVGSGLYDEAIRHFSTML-----------------------QEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNF 189
Cdd:COG0457    47 NLGLAYLRLGRYEEALADYEQALeldpddaealnnlglalqalgryEEALEDYDKALELDPDDAEALYNLGLALLELGRY 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 190 DAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVML 269
Cdd:COG0457   127 DEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1735137167 270 NDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYN 307
Cdd:COG0457   207 LRKKLAILTLAALAELLLLALALLLALRLAALALYQYR 244
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 116-238 6.16e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 72.15  E-value: 6.16e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 116 QKRFPFATDNDSTNEE--LAIAYVLVGSGLYDEairhfstmlqeAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAAT 193
Cdd:COG4783    24 EALLEKALELDPDNPEafALLGEILLQLGDLDE-----------AIVLLHEALELDPDEPEARLNLGLALLKAGDYDEAL 92

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1735137167 194 ESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 238
Cdd:COG4783    93 ALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
155-238 2.25e-14

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 69.04  E-value: 2.25e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAAtESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 234
Cdd:COG3063     8 LEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERAL 86


                  ....
gi 1735137167 235 QLEP 238
Cdd:COG3063    87 ELDP 90
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
143-238 1.25e-13

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 70.71  E-value: 1.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 143 LYDEAIRHFS-TMLQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHG 221
Cdd:COG4785    76 YYERGVAYDSlGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                          90
                  ....*....|....*..
gi 1735137167 222 SLQEALKNFKRCLQLEP 238
Cdd:COG4785   156 RYELAIADLEKALELDP 172
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 155-238 3.86e-13

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 67.68  E-value: 3.86e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 234
Cdd:COG5010    70 FEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149


                  ....
gi 1735137167 235 QLEP 238
Cdd:COG5010   150 GTSP 153
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 131-289 4.52e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.14  E-value: 4.52e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 131 ELAIAYVLvgSGLYDEAIRHFSTMLQ-----------------------EAIEAFKEALKQKVDFIDAYKSLGQAYRELG 187
Cdd:COG2956    13 FKGLNYLL--NGQPDKAIDLLEEALEldpetveahlalgnlyrrrgeydRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 188 NFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKV 267
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKA 170

                         170       180
                  ....*....|....*....|..
gi 1735137167 268 MlndplpgqKASPEYLRVKYLR 289
Cdd:COG2956   171 L--------KLDPDCARALLLL 184
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 154-273 1.05e-12

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 66.52  E-value: 1.05e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 154 MLQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRC 233
Cdd:COG5010    35 NNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKA 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1735137167 234 LQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPL 273
Cdd:COG5010   115 LALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 134-298 1.27e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.18  E-value: 1.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 134 IAYVLVGSGLYDEAIRHFSTMLQ-----------------------EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFD 190
Cdd:COG3914   118 LGNLLLALGRLEEALAALRRALAlnpdfaeaylnlgealrrlgrleEAIAALRRALELDPDNAEALNNLGNALQDLGRLE 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 191 AATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVC-----QYMKGLS-------HVAMGQFY 258
Cdd:COG3914   198 EAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELspfalLYLPDDDpaellalARAWAQLV 277

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1735137167 259 E-GIKAQTKVMLNDPLPGQKaspeyLRVKYLreySRYLHAH 298
Cdd:COG3914   278 AaAAAPELPPPPNPRDPDRK-----LRIGYV---SADFRRH 310
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 107-242 6.76e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 66.68  E-value: 6.76e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 107 LSQAKSIAEQkrfpfATDNDSTNEE--LAIAYVLVGSGLYDEAIRHFSTMLQ-----------------------EAIEA 161
Cdd:COG2956    92 LDRAEELLEK-----LLELDPDDAEalRLLAEIYEQEGDWEKAIEVLERLLKlgpenahaycelaelyleqgdydEAIEA 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 162 FKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNE 241
Cdd:COG2956   167 LEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDD 246


                  .
gi 1735137167 242 V 242
Cdd:COG2956   247 L 247
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 174-272 8.17e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.59  E-value: 8.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 174 DAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVA 253
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90
                  ....*....|....*....
gi 1735137167 254 MGQFYEGIKAQTKVMLNDP 272
Cdd:COG4783    85 AGDYDEALALLEKALKLDP 103
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
182-272 8.98e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 59.03  E-value: 8.98e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 182 AYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKnFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGI 261
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|.
gi 1735137167 262 KAQTKVMLNDP 272
Cdd:COG3063    80 AYLERALELDP 90
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 146-263 1.51e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.16  E-value: 1.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 146 EAIRHFSTMLQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQE 225
Cdd:COG3914    51 LAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEE 130

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1735137167 226 ALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKA 263
Cdd:COG3914   131 ALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAA 168
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
171-284 6.20e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 56.85  E-value: 6.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 171 DFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLS 250
Cdd:COG4785    71 DLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIA 150

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1735137167 251 HVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLR 284
Cdd:COG4785   151 LYYLGRYELAIADLEKALELDPNDPERALWLYLA 184
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 174-260 1.17e-08

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 57.25  E-value: 1.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 174 DAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKglshva 253
Cdd:cd24142     1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEKYLY------ 74


                  ....*..
gi 1735137167 254 MGQFYEG 260
Cdd:cd24142    75 LGQLSGG 81
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 104-288 1.17e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 1.17e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 104 EKILSQAKSIAEQkrfpfatdndSTNEELAIAYVLVGSGLYDEAirhfstmlQEAIEafkEALKQKVDFIDAYKSLGQAY 183
Cdd:TIGR02917 145 QKSYEQALAIDPR----------SLYAKLGLAQLALAENRFDEA--------RALID---EVLTADPGNVDALLLKGDLL 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 184 RELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKA 263
Cdd:TIGR02917 204 LSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARET 283

                         170       180
                  ....*....|....*....|....*
gi 1735137167 264 QTKVMlndplpgqKASPEYLRVKYL 288
Cdd:TIGR02917 284 LQDAL--------KSAPEYLPALLL 300
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 131-235 6.88e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 6.88e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 131 ELAIAYVlvGSGLYDEAIRHFSTMLQ-----------------------EAIEAFKEALKQKVDFIDAYKSLGQAYRELG 187
Cdd:COG2956   149 ELAELYL--EQGDYDEAIEALEKALKldpdcarallllaelyleqgdyeEAIAALERALEQDPDYLPALPRLAELYEKLG 226

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1735137167 188 NFDAATESFQKALLLNQNHVQTLQLrGMMLYHHGSLQEALKNFKRCLQ 235
Cdd:COG2956   227 DPEEALELLRKALELDPSDDLLLAL-ADLLERKEGLEAALALLERQLR 273
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
131-235 8.41e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 53.38  E-value: 8.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 131 ELAIAYVLVGsgLYDEAIRHFSTMLQ-----------------------EAIEAFKEALKQKVDFIDAYKSLGQAYRELG 187
Cdd:COG4785    78 ERGVAYDSLG--DYDLAIADFDQALEldpdlaeaynnrglaylllgdydAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1735137167 188 NFDAATESFQKALLLNQNHVQTLQLRG-------------------MMLY-HHGSLQEALKNFKRCLQ 235
Cdd:COG4785   156 RYELAIADLEKALELDPNDPERALWLYlaerkldpekalallledwATAYlLQGDTEEARELFKLALA 223
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 111-295 1.28e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.09  E-value: 1.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 111 KSIAEQKRFPfatdndstNEELAIAYVLVGSGLYDEAIRHFSTMLQEAI-EAFKEALKQKVDFidaykslgQAyrelGNF 189
Cdd:TIGR02917 218 KAIALRPNNI--------AVLLALATILIEAGEFEEAEKHADALLKKAPnSPLAHYLKALVDF--------QK----KNY 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 190 DAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIkAQTKVML 269
Cdd:TIGR02917 278 EDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAI-ATLSPAL 356

                         170       180       190
                  ....*....|....*....|....*....|
gi 1735137167 270 ----NDPLPGQKASPEYLRVKYLREYSRYL 295
Cdd:TIGR02917 357 gldpDDPAALSLLGEAYLALGDFEKAAEYL 386
PRK11189 PRK11189
lipoprotein NlpI; Provisional
 162-238 2.26e-07

lipoprotein NlpI; Provisional


Pssm-ID: 236875 [Multi-domain]  Cd Length: 296  Bit Score: 52.97  E-value: 2.26e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1735137167 162 FKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 238
Cdd:PRK11189   87 FSQALALRPDMADAYNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAYLNRGIALYYGGRYELAQDDLLAFYQDDP 163
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 131-216 2.53e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.00  E-value: 2.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 131 ELAIAYVLvgSGLYDEAIRHFSTMLQ-----------------------EAIEAFKEALKQKVDFIDAYKSLGQAYRELG 187
Cdd:COG4235    22 LLGRAYLR--LGRYDEALAAYEKALRldpdnadalldlaeallaagdteEAEELLERALALDPDNPEALYLLGLAAFQQG 99

                          90       100
                  ....*....|....*....|....*....
gi 1735137167 188 NFDAATESFQKALLLNQNHVQTLQLRGMM 216
Cdd:COG4235   100 DYAEAIAAWQKLLALLPADAPARLLEASI 128
TPR_1 pfam00515
Tetratricopeptide repeat;
173-206 9.86e-07

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 45.49  E-value: 9.86e-07
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1735137167 173 IDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 206
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 173-206 1.83e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 44.74  E-value: 1.83e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1735137167  173 IDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 206
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_12 pfam13424
Tetratricopeptide repeat;
134-200 2.69e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.46  E-value: 2.69e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1735137167 134 IAYVLVGSGLYDEAIRHFstmlQEAIEAFKEAL-KQKVDFIDAYKSLGQAYRELGNFDAATESFQKAL 200
Cdd:pfam13424   9 LAAVLRRLGRYDEALELL----EKALEIARRLLgPDHPLTATTLLNLGRLYLELGRYEEALELLERAL 72
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 156-238 1.44e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.60  E-value: 1.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 156 QEAIEAFKEALKQKVD---FIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQT---LQLRGMMLYHHGSLQEALKN 229
Cdd:COG1729    10 DEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKARAT 89


                  ....*....
gi 1735137167 230 FKRCLQLEP 238
Cdd:COG1729    90 LEELIKKYP 98
TPR_12 pfam13424
Tetratricopeptide repeat;
171-236 2.17e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.14  E-value: 2.17e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1735137167 171 DFIDAYKSLGQAYRELGNFDAATESFQKALLLNQ-----NHVQTLQLR---GMMLYHHGSLQEALKNFKRCLQL 236
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARrllgpDHPLTATTLlnlGRLYLELGRYEEALELLERALAL 74
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 126-262 2.85e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 2.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 126 DSTNEELAIA----YVLVGSglydeairhfstmLQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALL 201
Cdd:TIGR02917 563 NPQEIEPALAlaqyYLGKGQ-------------LKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLA 629

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1735137167 202 LNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIK 262
Cdd:TIGR02917 630 LQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKK 690
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 155-274 7.34e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 7.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 234
Cdd:TIGR02917 311 LEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKAT 390

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1735137167 235 QLEPYNEVCQYMKGLSHVAMGQFYEGIKA-QTKVMLNDPLP 274
Cdd:TIGR02917 391 ELDPENAAARTQLGISKLSQGDPSEAIADlETAAQLDPELG 431
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 105-286 7.86e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 7.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 105 KILSQAKSIAEQKRfpfatDNDSTNEELAIAYVlvGSGLYDEAIrhfstmlqeaiEAFKEALKQKVDFIDAYKSLGQAYR 184
Cdd:TIGR02917 449 KALAAAKKLEKKQP-----DNASLHNLLGAIYL--GKGDLAKAR-----------EAFEKALSIEPDFFPAAANLARIDI 510

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 185 ELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVcqymkglSHVAMGQFYEGIK-- 262
Cdd:TIGR02917 511 QEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIE-------PALALAQYYLGKGql 583

                         170       180
                  ....*....|....*....|....
gi 1735137167 263 AQTKVMLNDPLPGQKASPEYLRVK 286
Cdd:TIGR02917 584 KKALAILNEAADAAPDSPEAWLML 607
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 124-203 1.47e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 1.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 124 DNDSTNEELAIAYVLvgSGLYDEAIRHfstmlqeaieaFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLN 203
Cdd:COG5010    86 NNPELYYNLALLYSR--SGDKDEAKEY-----------YEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 174-205 2.81e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 38.66  E-value: 2.81e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1735137167 174 DAYKSLGQAYRELGNFDAATESFQKALLLNQN 205
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_19 pfam14559
Tetratricopeptide repeat;
155-213 2.96e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 39.49  E-value: 2.96e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLR 213
Cdd:pfam14559   4 YAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALL 62
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 132-257 3.29e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 3.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 132 LAIAYVLVGSG------LYDEAirhfSTMLQE-----AIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKAL 200
Cdd:TIGR02917   8 LCIALALSACGdqspeeLIEAA----KSYLQKnkykaAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKAL 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1735137167 201 LLNQNHVQTLQLRGMMLYHHGSLQEALKNF--KRCLQLEPYNEVCQYmKGLSHVAMGQF 257
Cdd:TIGR02917  84 SLGYPKNQVLPLLARAYLLQGKFQQVLDELpgKTLLDDEGAAELLAL-RGLAYLGLGQL 141
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 132-200 3.94e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 39.24  E-value: 3.94e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1735137167 132 LAIAYVLVGSGLYDEAIRHFstmlQEAIEAFKEALKQKvdfiDAYKSLGQAYRELGNFDAATESFQKAL 200
Cdd:pfam13432   1 LALARAALRAGDYDDAAAAL----EAALARFPESPDAA----AALLLLGLAALRQGRLAEAAAAYRAAL 61
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 119-262 5.86e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 43.05  E-value: 5.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 119 FPFATDNDSTNEELAIAYVLVGSglydeaIRHFSTMLQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQK 198
Cdd:TIGR00990 317 FEKALDLGKLGEKEAIALNLRGT------FKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDK 390

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1735137167 199 ALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYN-------EVCQYMKGLSHVAMGQFYEGIK 262
Cdd:TIGR00990 391 ALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFifshiqlGVTQYKEGSIASSMATFRRCKK 461
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 155-266 9.73e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 9.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 234
Cdd:TIGR02917 617 LNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQ 696

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1735137167 235 QLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTK 266
Cdd:TIGR02917 697 KQHPKAALGFELEGDLYLRQKDYPAAIQAYRK 728
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 179-241 1.35e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 37.70  E-value: 1.35e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1735137167 179 LGQAYRELGNFDAATESFQKALLLNQNHVQTLQ---LRGMMLYHHGSLQEALKNFKRCLQLEPYNE 241
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAALARFPESPDAAAallLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
158-257 1.42e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.67  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 158 AIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLlNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLE 237
Cdd:COG4785    25 LLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALA-LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELD 103

                          90       100
                  ....*....|....*....|
gi 1735137167 238 PYNEVCQYMKGLSHVAMGQF 257
Cdd:COG4785   104 PDLAEAYNNRGLAYLLLGDY 123
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 129-259 2.03e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 129 NEELAIAYVLVGSGlydeairHF-STMLQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHV 207
Cdd:TIGR02917 121 DEGAAELLALRGLA-------YLgLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNV 193

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1735137167 208 QTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYE 259
Cdd:TIGR02917 194 DALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEE 245
TPR_11 pfam13414
TPR repeat;
155-187 2.33e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.30  E-value: 2.33e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1735137167 155 LQEAIEAFKEALKQKVDFIDAYKSLGQAYRELG 187
Cdd:pfam13414  10 YEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 134-200 2.91e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.05  E-value: 2.91e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1735137167 134 IAYVLVGSGLYDEAIRHFstmlQEAIEAFKEalKQKVDfiDAYKSLGQAYRELGNFDAATESFQKAL 200
Cdd:COG1729    36 LGEAYYALGDYDEAAEAF----EKLLKRYPD--SPKAP--DALLKLGLSYLELGDYDKARATLEELI 94
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 131-273 3.05e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 3.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 131 ELAIAYVLVGSGLYDEAIRHFSTmlqeaieafkeALKQKVDFIDAYKSLGQAYRELGNfDAATESFQKALLLNQNHVQTL 210
Cdd:TIGR02917 773 RTALAELYLAQKDYDKAIKHYQT-----------VVKKAPDNAVVLNNLAWLYLELKD-PRALEYAERALKLAPNIPAIL 840

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1735137167 211 QLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYmkglsHVAMGQFYEGIKAQTKVMLNDPL 273
Cdd:TIGR02917 841 DTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRY-----HLALALLATGRKAEARKELDKLL 898
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 156-206 3.82e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.92  E-value: 3.82e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1735137167 156 QEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 206
Cdd:cd24142    17 ELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG 67
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 157-262 4.55e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 4.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 157 EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQL 236
Cdd:TIGR02917 551 EAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLAL 630

                          90       100
                  ....*....|....*....|....*.
gi 1735137167 237 EPYNevcqymkGLSHVAMGQFYEGIK 262
Cdd:TIGR02917 631 QPDS-------ALALLLLADAYAVMK 649
TPR_8 pfam13181
Tetratricopeptide repeat;
179-205 4.58e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 35.07  E-value: 4.58e-03
                          10        20
                  ....*....|....*....|....*..
gi 1735137167 179 LGQAYRELGNFDAATESFQKALLLNQN 205
Cdd:pfam13181   7 LGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 156-264 5.74e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 39.60  E-value: 5.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 156 QEAIEAFKEALKQ--KVDF---IDAYKSLGQAYRELGNFDAATESFQKA--LLLNQNH-----VQTLQLrGMMLYHHGSL 223
Cdd:pfam17874  18 ERALELAEQALALlpEDDLlarGLATFVLGEAYLCLGDLDAALQAMREAeaLARRADSphvtlWALLQQ-GEILRAQGRL 96

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1735137167 224 QEALKNFKRCLQLEPynevcqyMKGLSHVAMGQFYEGIKAQ 264
Cdd:pfam17874  97 HQALETYQQALQLAR-------DHGLQHLPLHGFLLVGLAD 130
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 154-272 5.78e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.02  E-value: 5.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 154 MLQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRC 233
Cdd:COG5010     1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1735137167 234 LQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 272
Cdd:COG5010    81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSP 119
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 109-238 6.14e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 6.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 109 QAKSIAEQKRFPFATDNDSTNEELAiAYVLVGSGLYDEAIRHF-------------------STMLQ----EAIEAFKEA 165
Cdd:TIGR02917 345 VDEAIATLSPALGLDPDDPAALSLL-GEAYLALGDFEKAAEYLakateldpenaaartqlgiSKLSQgdpsEAIADLETA 423

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1735137167 166 LKQKVDFIDAYKSLGQAYRELGNFDAATeSFQKALLLNQ-NHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 238
Cdd:TIGR02917 424 AQLDPELGRADLLLILSYLRSGQFDKAL-AAAKKLEKKQpDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEP 496
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 129-202 7.59e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.12  E-value: 7.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 129 NEELAIAYVLVGSGLYDEAIRHFSTMLQE-----------------------AIEAFKEALKQKVDfIDAYKSLGQAYRE 185
Cdd:COG3071   225 DPRLVRLYGRLQGGDPAKQLKRAEKWLKKhpndpdlllalgrlclrnqlwgkAREYLEAALALRPS-AEAYAELARLLEQ 303

                          90
                  ....*....|....*..
gi 1735137167 186 LGNFDAATESFQKALLL 202
Cdd:COG3071   304 LGDPEEAAEHYRKALAL 320
TPR_9 pfam13371
Tetratricopeptide repeat;
179-238 9.68e-03

Tetratricopeptide repeat;


Pssm-ID: 463860 [Multi-domain]  Cd Length: 73  Bit Score: 35.27  E-value: 9.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1735137167 179 LGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 238
Cdd:pfam13371   1 LKAIYLREEDWERALAVVERLLLLAPDDPEERRDRGLLYAQLGCFQAALEDLEAYLELAP 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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