NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1734334126|ref|NP_001359860|]
View 

CENP-V/GFA domain-containing protein [Caenorhabditis elegans]

Protein Classification

GFA family protein( domain architecture ID 10007990)

GFA family protein similar to bacterial glutathione-dependent formaldehyde-activating enzyme, which catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione, and to eukaryotic centromere protein V, which plays a role in the distribution of pericentromeric heterochromatin in interphase nuclei

CATH:  2.170.150.70
Gene Ontology:  GO:0016846|GO:0046872

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
COG3791 COG3791
Uncharacterized conserved protein [Function unknown];
8-110 9.84e-19

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443005  Cd Length: 132  Bit Score: 75.44  E-value: 9.84e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1734334126   8 GSCHCGAVKWSFTGPeVLDGCRCNCSVCDKKQ----NQHCIIKLDRFKLLEGEDKITVYRFnTGLAQHKFCSICGVQSFY 83
Cdd:COG3791     6 GSCLCGAVRFEVDGP-PLRVGACHCSICRKATgsafAAVALVPADAFRLTSGEDALTTYRS-SATAERHFCPTCGSPLFY 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1734334126  84 HPRSNPDAVG------------KPE-STWCQAVPSWLDLP 110
Cdd:COG3791    84 RRRGGPGLVAvnagllddpdglPPTaHIFTSSKPPWVEIP 123
 
Name Accession Description Interval E-value
COG3791 COG3791
Uncharacterized conserved protein [Function unknown];
8-110 9.84e-19

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443005  Cd Length: 132  Bit Score: 75.44  E-value: 9.84e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1734334126   8 GSCHCGAVKWSFTGPeVLDGCRCNCSVCDKKQ----NQHCIIKLDRFKLLEGEDKITVYRFnTGLAQHKFCSICGVQSFY 83
Cdd:COG3791     6 GSCLCGAVRFEVDGP-PLRVGACHCSICRKATgsafAAVALVPADAFRLTSGEDALTTYRS-SATAERHFCPTCGSPLFY 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1734334126  84 HPRSNPDAVG------------KPE-STWCQAVPSWLDLP 110
Cdd:COG3791    84 RRRGGPGLVAvnagllddpdglPPTaHIFTSSKPPWVEIP 123
 
Name Accession Description Interval E-value
COG3791 COG3791
Uncharacterized conserved protein [Function unknown];
8-110 9.84e-19

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443005  Cd Length: 132  Bit Score: 75.44  E-value: 9.84e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1734334126   8 GSCHCGAVKWSFTGPeVLDGCRCNCSVCDKKQ----NQHCIIKLDRFKLLEGEDKITVYRFnTGLAQHKFCSICGVQSFY 83
Cdd:COG3791     6 GSCLCGAVRFEVDGP-PLRVGACHCSICRKATgsafAAVALVPADAFRLTSGEDALTTYRS-SATAERHFCPTCGSPLFY 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1734334126  84 HPRSNPDAVG------------KPE-STWCQAVPSWLDLP 110
Cdd:COG3791    84 RRRGGPGLVAvnagllddpdglPPTaHIFTSSKPPWVEIP 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH