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Conserved domains on  [gi|1634229931|ref|NP_001357315|]
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zinc finger protein 266 isoform 1 [Homo sapiens]

Protein Classification

KRAB domain-containing zinc finger protein( domain architecture ID 18089471)

KRAB (Kruppel-associated box) domain-containing zinc finger protein (KRAB-ZFP) plays important roles in cell differentiation and organ development and in regulating viral replication and transcription

CATH:  3.30.160.60|1.10.287.1360
Gene Ontology:  GO:0005515|GO:0008270|GO:0003677|GO:0006355|GO:0001217|GO:0003700
PubMed:  8183940|22803940|2023909|8183939|10748030|27867147|28765213|11361095|30718982|10940247
SCOP:  4003583|4002243

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
210-549 4.66e-08

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.47  E-value: 4.66e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 210 KPYKCKECGKGFRYSAYLNIHMGTHTGDNPYEC--KECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQ-H 286
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSlS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 287 MKIHVGEKPYECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPykckdCGKAFTQNSD 366
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 367 LTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTgEKPFECVKCGKAFAISSNLSGHLRIHTGEKPFECLEC----- 441
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESprssl 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 442 GKAFTHSSSLNNH-MRTHSAK-KPFTCMECGKAFKFPTCVNLHMR--IHTGE--KPYKC--KQCGKSFSYSNSFQLHERT 513
Cdd:COG5048   266 PTASSQSSSPNESdSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1634229931 514 HTGEKPYECK--ECGKAFSSSSSFRNHERRHADERLSA 549
Cdd:COG5048   346 HTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKN 383
KRAB super family cl42959
krueppel associated box;
1-28 5.82e-08

krueppel associated box;


The actual alignment was detected with superfamily member smart00349:

Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 49.51  E-value: 5.82e-08
                           10        20
                   ....*....|....*....|....*...
gi 1634229931    1 MLENYKNLATVGYQLFKPSLISWLEQEE 28
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGE 57
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
210-549 4.66e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.47  E-value: 4.66e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 210 KPYKCKECGKGFRYSAYLNIHMGTHTGDNPYEC--KECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQ-H 286
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSlS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 287 MKIHVGEKPYECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPykckdCGKAFTQNSD 366
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 367 LTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTgEKPFECVKCGKAFAISSNLSGHLRIHTGEKPFECLEC----- 441
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESprssl 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 442 GKAFTHSSSLNNH-MRTHSAK-KPFTCMECGKAFKFPTCVNLHMR--IHTGE--KPYKC--KQCGKSFSYSNSFQLHERT 513
Cdd:COG5048   266 PTASSQSSSPNESdSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1634229931 514 HTGEKPYECK--ECGKAFSSSSSFRNHERRHADERLSA 549
Cdd:COG5048   346 HTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKN 383
KRAB smart00349
krueppel associated box;
1-28 5.82e-08

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 49.51  E-value: 5.82e-08
                           10        20
                   ....*....|....*....|....*...
gi 1634229931    1 MLENYKNLATVGYQLFKPSLISWLEQEE 28
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGE 57
zf-H2C2_2 pfam13465
Zinc-finger double domain;
482-503 1.17e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.17e-04
                          10        20
                  ....*....|....*....|..
gi 1634229931 482 HMRIHTGEKPYKCKQCGKSFSY 503
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
 295-342 9.27e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.78  E-value: 9.27e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1634229931 295 PYECKECGIAFTRSSQLTEHLK--THTAKdpfeCKICGKSFRNSSCLSDH 342
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRytEHSKV----CPVCGKEFRNTDSTLDH 118
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
210-549 4.66e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.47  E-value: 4.66e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 210 KPYKCKECGKGFRYSAYLNIHMGTHTGDNPYEC--KECGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCLSQ-H 286
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSlS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 287 MKIHVGEKPYECKECGIAFTRSSQLTEHLKTHTAKDPFECKICGKSFRNSSCLSDHFRIHTGIKPykckdCGKAFTQNSD 366
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPANSL-----SKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 367 LTKHARTHSGERPYECKECGKAFARSSRLSEHTRTHTgEKPFECVKCGKAFAISSNLSGHLRIHTGEKPFECLEC----- 441
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESprssl 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 442 GKAFTHSSSLNNH-MRTHSAK-KPFTCMECGKAFKFPTCVNLHMR--IHTGE--KPYKC--KQCGKSFSYSNSFQLHERT 513
Cdd:COG5048   266 PTASSQSSSPNESdSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 1634229931 514 HTGEKPYECK--ECGKAFSSSSSFRNHERRHADERLSA 549
Cdd:COG5048   346 HTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKN 383
KRAB smart00349
krueppel associated box;
1-28 5.82e-08

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 49.51  E-value: 5.82e-08
                           10        20
                   ....*....|....*....|....*...
gi 1634229931    1 MLENYKNLATVGYQLFKPSLISWLEQEE 28
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGE 57
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
164-359 2.47e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 2.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 164 SFINHSHLQGHLRTHNGESlHEWKECGRGFIHSTDLAVRIQTH----------RSEKPYKCKECGKGFRYSAYLNIHMGT 233
Cdd:COG5048   233 SQLSPKSLLSQSPSSLSSS-DSSSSASESPRSSLPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRS 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 234 --HTGDN--PYECKE--CGKAFTRSCQLTQHRKTHTGEKPYKCKDCGRAFTVSSCL-------SQHMKIHVGEKPYEC-- 298
Cdd:COG5048   312 vnHSGESlkPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLnneppqsLQQYKDLKNDKKSETls 391

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1634229931 299 KECGIAFTRSSQLTEHLKTHTAKDP--FECKICGKSFRNSSCLSDHFRIHTGIKPYKCKDCGK 359
Cdd:COG5048   392 NSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
294-480 4.35e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.39  E-value: 4.35e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 294 KPYECKECGIAFTRSSQLTEHLKT--HTAKD--PFECKI--CGKSFRNSSCLSDHFRIHTGIKPYKCK--DCGKAFTQNS 365
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGESlkPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKllNSSSKFSPLL 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 366 DLTKHARTH-----SGERPYEC--KECGKAFARSSRLSEHTRTHTGEKPfecvkcgkafaissnlsghlrihtgeKPFEC 438
Cdd:COG5048   368 NNEPPQSLQqykdlKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRP--------------------------YNCKN 421

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1634229931 439 LECGKAFTHSSSLNNHMRTHSAKKPFTCMECGKAFKFPTCVN 480
Cdd:COG5048   422 PPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSN 463
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
335-538 1.97e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.38  E-value: 1.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 335 NSSCLSDHFRIhtgIKPYKCKDCGKAFTQNSDLTKHART--HSGE--RPYECKE--CGKAFARSSRLSEHTRTHTGEKPF 408
Cdd:COG5048   276 NESDSSSEKGF---SLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPA 352

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 409 ECV--KCGKAFAISSNLSGHLRIH-----TGEKPFECLecgkaftHSSSLNNHMRTHSAKKPFTCmecgkafkfptcvNL 481
Cdd:COG5048   353 KEKllNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETL-------SNSCIRNFKRDSNLSLHIIT-------------HL 412

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1634229931 482 HMRIHtgekPYKCKQCGKSFSYSNSFQLHERTHTGEKPYECkECGKAFSSSSSFRNH 538
Cdd:COG5048   413 SFRPY----NCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNH 464
zf-H2C2_2 pfam13465
Zinc-finger double domain;
482-503 1.17e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.28  E-value: 1.17e-04
                          10        20
                  ....*....|....*....|..
gi 1634229931 482 HMRIHTGEKPYKCKQCGKSFSY 503
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
506-531 4.30e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 4.30e-04
                          10        20
                  ....*....|....*....|....*.
gi 1634229931 506 SFQLHERTHTGEKPYECKECGKAFSS 531
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
422-447 8.71e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 8.71e-04
                          10        20
                  ....*....|....*....|....*.
gi 1634229931 422 NLSGHLRIHTGEKPFECLECGKAFTH 447
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
339-363 1.24e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.24e-03
                          10        20
                  ....*....|....*....|....*
gi 1634229931 339 LSDHFRIHTGIKPYKCKDCGKAFTQ 363
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 352-374 1.45e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.12  E-value: 1.45e-03
                          10        20
                  ....*....|....*....|...
gi 1634229931 352 YKCKDCGKAFTQNSDLTKHARTH 374
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
366-391 1.51e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.51e-03
                          10        20
                  ....*....|....*....|....*.
gi 1634229931 366 DLTKHARTHSGERPYECKECGKAFAR 391
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
450-474 1.57e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 1.57e-03
                          10        20
                  ....*....|....*....|....*
gi 1634229931 450 SLNNHMRTHSAKKPFTCMECGKAFK 474
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
255-278 2.26e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 2.26e-03
                          10        20
                  ....*....|....*....|....
gi 1634229931 255 LTQHRKTHTGEKPYKCKDCGRAFT 278
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 432-515 2.76e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.47  E-value: 2.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1634229931 432 GEKPFEC--LECGKAFTHSSSLNNHMRtHSAKKPFTcmecgkafkFPTCVNLHMRIHTGE-KPYKCKQCGKSFSYSNSFQ 508
Cdd:COG5189   346 DGKPYKCpvEGCNKKYKNQNGLKYHML-HGHQNQKL---------HENPSPEKMNIFSAKdKPYRCEVCDKRYKNLNGLK 415


                  ....*..
gi 1634229931 509 LHeRTHT 515
Cdd:COG5189   416 YH-RKHS 421
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 436-458 2.96e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.35  E-value: 2.96e-03
                          10        20
                  ....*....|....*....|...
gi 1634229931 436 FECLECGKAFTHSSSLNNHMRTH 458
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
283-307 3.06e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 3.06e-03
                          10        20
                  ....*....|....*....|....*
gi 1634229931 283 LSQHMKIHVGEKPYECKECGIAFTR 307
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
226-251 3.51e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.51e-03
                          10        20
                  ....*....|....*....|....*.
gi 1634229931 226 YLNIHMGTHTGDNPYECKECGKAFTR 251
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
 295-342 9.27e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.78  E-value: 9.27e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1634229931 295 PYECKECGIAFTRSSQLTEHLK--THTAKdpfeCKICGKSFRNSSCLSDH 342
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRytEHSKV----CPVCGKEFRNTDSTLDH 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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