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Conserved domains on  [gi|1488192443|ref|NP_001353465|]
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tetratricopeptide repeat protein 8 isoform H [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 30-154 1.24e-78

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


:

Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 240.28  E-value: 1.24e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443  30 MLEKSPYDQAAWILKARALTEMVYIDEIDVDQEGIAEMMLDENAIAQVPRPGTSLKLPGTNQtGGPSQAVRPITQAGRPI 109
Cdd:cd21341     1 LLEKNPYDQAAWFLKMRALTEQVYIDDTEVDEEGIAELLMDENVIATVPRPGTSLRRPTTSA-GGPSQAMRPTTSSGRPI 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1488192443 110 TGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTA 154
Cdd:cd21341    80 TGFVRPGTQSGRPGTSRQALRTPRRAGTARPVTSASGRFVRLGTA 124
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 192-426 1.29e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.03  E-value: 1.29e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 192 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSS 270
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 271 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLA 350
Cdd:COG2956    95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192443 351 ENeeeAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQKSEAA 426
Cdd:COG2956   175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247
 
Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 30-154 1.24e-78

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 240.28  E-value: 1.24e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443  30 MLEKSPYDQAAWILKARALTEMVYIDEIDVDQEGIAEMMLDENAIAQVPRPGTSLKLPGTNQtGGPSQAVRPITQAGRPI 109
Cdd:cd21341     1 LLEKNPYDQAAWFLKMRALTEQVYIDDTEVDEEGIAELLMDENVIATVPRPGTSLRRPTTSA-GGPSQAMRPTTSSGRPI 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1488192443 110 TGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTA 154
Cdd:cd21341    80 TGFVRPGTQSGRPGTSRQALRTPRRAGTARPVTSASGRFVRLGTA 124
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 192-426 1.29e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.03  E-value: 1.29e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 192 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSS 270
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 271 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLA 350
Cdd:COG2956    95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192443 351 ENeeeAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQKSEAA 426
Cdd:COG2956   175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 190-420 1.94e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.55  E-value: 1.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 190 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTAL------------------------------ 238
Cdd:TIGR02917  61 LLGKIYLALGDYAAAEKELRKALSLGyPKNQVLPLLARAYLLQGKFQQVLdelpgktllddegaaellalrglaylglgq 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 239 -----NLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLL 313
Cdd:TIGR02917 141 lelaqKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAI 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 314 QMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAAdvwYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEA 393
Cdd:TIGR02917 221 ALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAH---YLKALVDFQKKNYEDARETLQDALKSAPEYLPA 297

                         250       260
                  ....*....|....*....|....*..
gi 1488192443 394 YNNLAVLEMRKGHVEQIGDLQRSYVAA 420
Cdd:TIGR02917 298 LLLAGASEYQLGNLEQAYQYLNQILKY 324
TPR_12 pfam13424
Tetratricopeptide repeat;
324-384 2.60e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.29  E-value: 2.60e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192443 324 NNLGLCCFYAQQYDMTLTSFERALSLAENE-----EEAADVWYNLGHVAVGIGDTNLAHQCFRLAL 384
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhPLTATTLLNLGRLYLELGRYEEALELLERAL 72
LPA1 PLN03098
LOW PSII ACCUMULATION1; Provisional
 325-388 2.30e-03

LOW PSII ACCUMULATION1; Provisional


Pssm-ID: 215573 [Multi-domain]  Cd Length: 453  Bit Score: 40.26  E-value: 2.30e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1488192443 325 NLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNN 388
Cdd:PLN03098   80 NLGLSLFSKGRVKDALAQFETALELNPNPDEAQAAYYNKACCHAYREEGKKAADCLRTALRDYN 143
 
Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 30-154 1.24e-78

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 240.28  E-value: 1.24e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443  30 MLEKSPYDQAAWILKARALTEMVYIDEIDVDQEGIAEMMLDENAIAQVPRPGTSLKLPGTNQtGGPSQAVRPITQAGRPI 109
Cdd:cd21341     1 LLEKNPYDQAAWFLKMRALTEQVYIDDTEVDEEGIAELLMDENVIATVPRPGTSLRRPTTSA-GGPSQAMRPTTSSGRPI 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1488192443 110 TGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTA 154
Cdd:cd21341    80 TGFVRPGTQSGRPGTSRQALRTPRRAGTARPVTSASGRFVRLGTA 124
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 192-426 1.29e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.03  E-value: 1.29e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 192 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSS 270
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 271 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLA 350
Cdd:COG2956    95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192443 351 ENeeeAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQKSEAA 426
Cdd:COG2956   175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
249-426 3.75e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 89.30  E-value: 3.75e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 249 PGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGL 328
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 329 CCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVE 408
Cdd:COG0457    85 ALQALGRYEEALEDYDKALELDPDD---AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161

                         170
                  ....*....|....*....
gi 1488192443 409 Q-IGDLQRSYVAAQKSEAA 426
Cdd:COG0457   162 EaLELLEKLEAAALAALLA 180
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
216-442 2.47e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 83.90  E-value: 2.47e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 216 EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSN 295
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 296 HFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHVAVGIGDTNL 375
Cdd:COG0457    86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADA---LYNLGIALEKLGRYEE 162

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1488192443 376 AHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQKSEAAFPDHVDTQHLIKQLRQ 442
Cdd:COG0457   163 ALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALAL 229
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
191-421 2.40e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 81.21  E-value: 2.40e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 191 IGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMS 269
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKALElDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 270 SAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSL 349
Cdd:COG0457    94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1488192443 350 AENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQ 421
Cdd:COG0457   174 ALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 221-443 1.53e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 79.39  E-value: 1.53e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 221 FLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSD 300
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 301 QPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQCF 380
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN---AHAYCELAELYLEQGDYDEAIEAL 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1488192443 381 RLALVNNNNHAEAYNNLAVLEMRKGHVEQigdlqrSYVAAQKSEAAFPDHVDTQHLIKQLRQH 443
Cdd:COG2956   168 EKALKLDPDCARALLLLAELYLEQGDYEE------AIAALERALEQDPDYLPALPRLAELYEK 224
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 189-384 3.75e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 78.23  E-value: 3.75e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 189 VQIGKCYYRLGMYREAEKQFKSALKQQEM-VDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNN 267
Cdd:COG2956    80 LELAQDYLKAGLLDRAEELLEKLLELDPDdAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGD 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 268 MSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERAL 347
Cdd:COG2956   160 YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAL 239

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1488192443 348 SLAENeeeaADVWYNLGHVAVGIGDTNLAHQCFRLAL 384
Cdd:COG2956   240 ELDPS----DDLLLALADLLERKEGLEAALALLERQL 272
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 190-421 9.05e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.38  E-value: 9.05e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 190 QIGKCYYRLGMYREAEKQFKSALKQQEMVDTFLY-LAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNM 268
Cdd:COG2956    47 ALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLeLAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDW 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 269 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALs 348
Cdd:COG2956   127 EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL- 205

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1488192443 349 laENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNhAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQ 421
Cdd:COG2956   206 --EQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 215-353 4.60e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.07  E-value: 4.60e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 215 QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGS 294
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1488192443 295 NHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENE 353
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 190-315 4.78e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.07  E-value: 4.78e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 190 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNM 268
Cdd:COG4783     9 ALAQALLLAGDYDEAEALLEKALELDpDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDY 88

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1488192443 269 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQM 315
Cdd:COG4783    89 DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 254-445 7.31e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 70.41  E-value: 7.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 254 LLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYA 333
Cdd:COG3914    80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 334 QQYDMTLTSFERALSLAENEEEAadvWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDL 413
Cdd:COG3914   160 GRLEEAIAALRRALELDPDNAEA---LNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRF 236

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1488192443 414 QRSYVAAQKSEAAFP------DHVDTQHLIKQLRQHFA 445
Cdd:COG3914   237 EELLAALARGPSELSpfallyLPDDDPAELLALARAWA 274
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
279-409 1.59e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 66.95  E-value: 1.59e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 279 LKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLaenEEEAAD 358
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL---DPDDAE 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1488192443 359 VWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQ 409
Cdd:COG0457    78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 292-409 2.40e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.06  E-value: 2.40e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 292 IGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHVAVGIG 371
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEA---RLNLGLALLKAG 86

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1488192443 372 DTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQ 409
Cdd:COG4783    87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDE 124
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
190-314 6.99e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.03  E-value: 6.99e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 190 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNM 268
Cdd:COG0457    47 NLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRY 126

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1488192443 269 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQ 314
Cdd:COG0457   127 DEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEA 172
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 158-314 3.54e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.59  E-value: 3.54e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 158 YIFHHENDVKTALD----LAALSTEHSQYKdwwwkVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLD 232
Cdd:COG2956   118 EIYEQEGDWEKAIEvlerLLKLGPENAHAY-----CELAELYLEQGDYDEAIEALEKALKLDpDCARALLLLAELYLEQG 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 233 QPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIAcIGSNHFYSDQPEIALRFYRRL 312
Cdd:COG2956   193 DYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLERKEGLEAALALLERQ 271


                  ..
gi 1488192443 313 LQ 314
Cdd:COG2956   272 LR 273
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 258-390 1.75e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 58.66  E-value: 1.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 258 IARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYD 337
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1488192443 338 MTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNH 390
Cdd:COG4783    90 EALALLEKALKLDPEH---PEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 203-315 1.87e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.48  E-value: 1.87e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 203 EAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQ 281
Cdd:COG4235     1 EAIARLRQALAANpNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1488192443 282 DNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQM 315
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 237-359 1.46e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 1.46e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 237 ALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMG 316
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1488192443 317 IYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADV 359
Cdd:COG4235    82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLL 124
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 191-288 4.92e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 4.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 191 IGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMS 269
Cdd:COG3914   118 LGNLLLALGRLEEALAALRRALALNpDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLE 197

                          90
                  ....*....|....*....
gi 1488192443 270 SAAEYYKEVLKQDNTHVEA 288
Cdd:COG3914   198 EAIAAYRRALELDPDNADA 216
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
194-282 1.51e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 52.09  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 194 CYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNlFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAA 272
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDpDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|
gi 1488192443 273 EYYKEVLKQD 282
Cdd:COG3063    80 AYLERALELD 89
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 183-290 2.55e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.32  E-value: 2.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 183 KDWWWKVQIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARI 261
Cdd:COG4235    15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRlDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLA 94

                          90       100
                  ....*....|....*....|....*....
gi 1488192443 262 YEEMNNMSSAAEYYKEVLKQDNTHVEAIA 290
Cdd:COG4235    95 AFQQGDYAEAIAAWQKLLALLPADAPARL 123
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 319-415 1.71e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.00  E-value: 1.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 319 NGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLA 398
Cdd:COG4235    16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN---ADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLG 92

                          90
                  ....*....|....*...
gi 1488192443 399 VLEMRKGHVEQ-IGDLQR 415
Cdd:COG4235    93 LAAFQQGDYAEaIAAWQK 110
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 190-420 1.94e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.55  E-value: 1.94e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 190 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTAL------------------------------ 238
Cdd:TIGR02917  61 LLGKIYLALGDYAAAEKELRKALSLGyPKNQVLPLLARAYLLQGKFQQVLdelpgktllddegaaellalrglaylglgq 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 239 -----NLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLL 313
Cdd:TIGR02917 141 lelaqKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAI 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 314 QMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAAdvwYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEA 393
Cdd:TIGR02917 221 ALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAH---YLKALVDFQKKNYEDARETLQDALKSAPEYLPA 297

                         250       260
                  ....*....|....*....|....*..
gi 1488192443 394 YNNLAVLEMRKGHVEQIGDLQRSYVAA 420
Cdd:TIGR02917 298 LLLAGASEYQLGNLEQAYQYLNQILKY 324
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 193-281 2.09e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 49.22  E-value: 2.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 193 KCYYRLGMYREAEKQFKSALKQ----QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTL---LCGIARIYEEM 265
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRypnsPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLEL 80

                          90
                  ....*....|....*.
gi 1488192443 266 NNMSSAAEYYKEVLKQ 281
Cdd:COG1729    81 GDYDKARATLEELIKK 96
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 193-384 6.92e-07

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 51.06  E-value: 6.92e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 193 KCYYRLGMYREAEKQFKSALKQQEMVDTFL--YLAKVYV-SLDQPVTALNLFKQGLDKFPGE----VTLLCGIARIYEEM 265
Cdd:COG3071   127 QAYRQLGDWEELLELLPALRKHKALSAEEAqaLERRAYLgLLRQAARDAEALKALWKALPRAerrdPELAAAYARALIAL 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 266 NNMSSAAEYYKEVLKQdNTHVEAIACIGSNHfySDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFER 345
Cdd:COG3071   207 GDHDEAERLLREALKR-QWDPRLVRLYGRLQ--GGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEA 283

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1488192443 346 ALSLAENeeeaADVWYNLGHVAVGIGDTNLAHQCFRLAL 384
Cdd:COG3071   284 ALALRPS----AEAYAELARLLEQLGDPEEAAEHYRKAL 318
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 198-420 2.23e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 2.23e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 198 LGMYREAEKQFKSALK-QQEMVDT-------FLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMS 269
Cdd:TIGR02917 573 LAQYYLGKGQLKKALAiLNEAADAapdspeaWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYA 652

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 270 SAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSL 349
Cdd:TIGR02917 653 KAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKR 732

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1488192443 350 AENEEEAAdvwyNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLA-VLEMRK------GHVEQIGDLQRSYVAA 420
Cdd:TIGR02917 733 APSSQNAI----KLHRALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAeLYLAQKdydkaiKHYQTVVKKAPDNAVV 806
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 300-409 3.14e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.88  E-value: 3.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 300 DQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQC 379
Cdd:COG5010    34 ANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNN---PELYYNLALLYSRSGDKDEAKEY 110

                          90       100       110
                  ....*....|....*....|....*....|
gi 1488192443 380 FRLALVNNNNHAEAYNNLAVLEMRKGHVEQ 409
Cdd:COG5010   111 YEKALALSPDNPNAYSNLAALLLSLGQDDE 140
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 192-433 4.95e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 4.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 192 GKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSS 270
Cdd:TIGR02917 608 GRAQLAAGDLNKAVSSFKKLLALQpDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTES 687

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 271 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQmgiyngqlfnnlglccfyAQQYDMTLTSFERALSLA 350
Cdd:TIGR02917 688 AKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALK------------------RAPSSQNAIKLHRALLAS 749

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 351 ENEEEAADV---W-----------YNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRS 416
Cdd:TIGR02917 750 GNTAEAVKTleaWlkthpndavlrTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRALEYAERA 829

                         250
                  ....*....|....*..
gi 1488192443 417 YvaaqKSEAAFPDHVDT 433
Cdd:TIGR02917 830 L----KLAPNIPAILDT 842
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 326-442 7.02e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.57  E-value: 7.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 326 LGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKg 405
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEA---FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA- 85

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1488192443 406 hveqiGDLQRSYVAAQKSEAAFPDHVDTQHLIKQLRQ 442
Cdd:COG4783    86 -----GDYDEALALLEKALKLDPEHPEAYLRLARAYR 117
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
333-409 7.64e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.39  E-value: 7.64e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1488192443 333 AQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQcFRLALVNNNNHAEAYNNLAVLEMRKGHVEQ 409
Cdd:COG3063     5 LGDLEEAEEYYEKALELDPDN---ADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDE 77
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
296-384 1.13e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.62  E-value: 1.13e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 296 HFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLtSFERALSLAENEeeaADVWYNLGHVAVGIGDTNL 375
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNN---AEALLNLAELLLELGDYDE 77


                  ....*....
gi 1488192443 376 AHQCFRLAL 384
Cdd:COG3063    78 ALAYLERAL 86
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 296-387 1.23e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.34  E-value: 1.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 296 HFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNL 375
Cdd:COG5010    64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDN---PNAYSNLAALLLSLGQDDE 140

                          90
                  ....*....|..
gi 1488192443 376 AHQCFRLALVNN 387
Cdd:COG5010   141 AKAALQRALGTS 152
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 90-399 1.33e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 1.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443  90 NQTGGPSQAVRPITQAGRPITGFLRPSTQSGR----PGTMEQAIRTPRTAYTARPitSSSGRFVRLGTALFEyIFHHEND 165
Cdd:TIGR02917 544 LRTGNEEEAVAWLEKAAELNPQEIEPALALAQyylgKGQLKKALAILNEAADAAP--DSPEAWLMLGRAQLA-AGDLNKA 620

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 166 VKTALDLAALSTEHSQYKdwwwkVQIGKCYYRLGMYREAEKQFKSALKQQE-MVDTFLYLAKVYVSLDQPVTALNLFKQG 244
Cdd:TIGR02917 621 VSSFKKLLALQPDSALAL-----LLLADAYAVMKNYAKAITSLKRALELKPdNTEAQIGLAQLLLAAKRTESAKKIAKSL 695

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 245 LDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAI----ACIGS----------NHFYSDQPE-IALRF- 308
Cdd:TIGR02917 696 QKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIklhrALLASgntaeavktlEAWLKTHPNdAVLRTa 775

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 309 -----------------YRRLLQMGIYNGQLFNNLGLccFYAQQYD-MTLTSFERALSLAENEEEAADVwynLGHVAVGI 370
Cdd:TIGR02917 776 laelylaqkdydkaikhYQTVVKKAPDNAVVLNNLAW--LYLELKDpRALEYAERALKLAPNIPAILDT---LGWLLVEK 850

                         330       340
                  ....*....|....*....|....*....
gi 1488192443 371 GDTNLAHQCFRLALVNNNNHAEAYNNLAV 399
Cdd:TIGR02917 851 GEADRALPLLRKAVNIAPEAAAIRYHLAL 879
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 190-250 1.33e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.21  E-value: 1.33e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1488192443 190 QIGKCYYRLGMYREAEKQFKSALKQ----QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPG 250
Cdd:COG1729    35 WLGEAYYALGDYDEAAEAFEKLLKRypdsPKAPDALLKLGLSYLELGDYDKARATLEELIKKYPD 99
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 189-311 1.81e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 46.91  E-value: 1.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 189 VQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNN 267
Cdd:COG3914   150 LNLGEALRRLGRLEEAIAALRRALELDpDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACD 229

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1488192443 268 mSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRR 311
Cdd:COG3914   230 -WEVYDRFEELLAALARGPSELSPFALLYLPDDDPAELLALARA 272
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 192-409 1.86e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 1.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 192 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSS 270
Cdd:TIGR02917  29 AKSYLQKNKYKAAIIQLKNALQKdPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQ 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 271 AAEYYKEVLKQDN-THVEAIACIGSNHFYSDQPEIALRFYRRLLQmgIYNGQLFNNLGLccfyAQ------QYDMTLTSF 343
Cdd:TIGR02917 109 VLDELPGKTLLDDeGAAELLALRGLAYLGLGQLELAQKSYEQALA--IDPRSLYAKLGL----AQlalaenRFDEARALI 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192443 344 ERALSLaenEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQ 409
Cdd:TIGR02917 183 DEVLTA---DPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEE 245
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 169-282 2.97e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.18  E-value: 2.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 169 ALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDK 247
Cdd:COG5010    38 KEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDpNNPELYYNLALLYSRSGDKDEAKEYYEKALAL 117

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1488192443 248 FPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQD 282
Cdd:COG5010   118 SPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
321-417 4.00e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.91  E-value: 4.00e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 321 QLFNNLGLCCFYAQQYDMTLTSFERALSLaenEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVL 400
Cdd:COG4785    74 QLYYERGVAYDSLGDYDLAIADFDQALEL---DPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIA 150

                          90
                  ....*....|....*...
gi 1488192443 401 EMRKGHVEQ-IGDLQRSY 417
Cdd:COG4785   151 LYYLGRYELaIADLEKAL 168
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 260-350 5.73e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 5.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 260 RIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMT 339
Cdd:COG5010    62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141

                          90
                  ....*....|.
gi 1488192443 340 LTSFERALSLA 350
Cdd:COG5010   142 KAALQRALGTS 152
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 204-405 1.05e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.69  E-value: 1.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 204 AEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQD 282
Cdd:TIGR02917 518 AIQRFEKVLTIDpKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAA 597

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 283 NTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVwyn 362
Cdd:TIGR02917 598 PDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIG--- 674

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1488192443 363 LGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKG 405
Cdd:TIGR02917 675 LAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQK 717
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 201-314 1.26e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.25  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 201 YREAEKQFKSALKQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLK 280
Cdd:COG5010    37 TKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALA 116

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1488192443 281 QDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQ 314
Cdd:COG5010   117 LSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
261-350 1.32e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 261 IYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFyRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTL 340
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|
gi 1488192443 341 TSFERALSLA 350
Cdd:COG3063    80 AYLERALELD 89
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
305-415 1.46e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.98  E-value: 1.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 305 ALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENeeeAADVWYNLGHVAVGIGDTNLAHQCFRLAL 384
Cdd:COG4785    92 AIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD---YAYAYLNRGIALYYLGRYELAIADLEKAL 168

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1488192443 385 VNNNNHAEAYNNLAVLEMRKGHVEQIGDLQR 415
Cdd:COG4785   169 ELDPNDPERALWLYLAERKLDPEKALALLLE 199
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 158-251 2.51e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.95  E-value: 2.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 158 YIFHHENDVKTALDLAALSTEHSQyKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVT 236
Cdd:COG4783    46 EILLQLGDLDEAIVLLHEALELDP-DEPEARLNLGLALLKAGDYDEALALLEKALKLDpEHPEAYLRLARAYRALGRPDE 124

                          90
                  ....*....|....*
gi 1488192443 237 ALNLFKQGLDKFPGE 251
Cdd:COG4783   125 AIAALEKALELDPDD 139
TPR_12 pfam13424
Tetratricopeptide repeat;
324-384 2.60e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.29  E-value: 2.60e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192443 324 NNLGLCCFYAQQYDMTLTSFERALSLAENE-----EEAADVWYNLGHVAVGIGDTNLAHQCFRLAL 384
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhPLTATTLLNLGRLYLELGRYEEALELLERAL 72
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 195-440 8.88e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 8.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 195 YYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAE 273
Cdd:TIGR02917 441 YLRSGQFDKALAAAKKLEKKQpDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQ 520

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 274 YYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLlqMGIYNGQLFNNLGLCCFYAQQYDMTLtSFERALSLAENE 353
Cdd:TIGR02917 521 RFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKA--AELNPQEIEPALALAQYYLGKGQLKK-ALAILNEAADAA 597

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 354 EEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQigdLQRSYvaaQKSEAAFPDHVDT 433
Cdd:TIGR02917 598 PDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAK---AITSL---KRALELKPDNTEA 671


                  ....*..
gi 1488192443 434 QHLIKQL 440
Cdd:TIGR02917 672 QIGLAQL 678
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 192-245 9.81e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 41.05  E-value: 9.81e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1488192443 192 GKCYYRLGMYREAEKQFKSALKQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGL 245
Cdd:COG3071   265 GRLCLRNQLWGKAREYLEAALALRPSAEAYAELARLLEQLGDPEEAAEHYRKAL 318
LPA1 PLN03098
LOW PSII ACCUMULATION1; Provisional
 325-388 2.30e-03

LOW PSII ACCUMULATION1; Provisional


Pssm-ID: 215573 [Multi-domain]  Cd Length: 453  Bit Score: 40.26  E-value: 2.30e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1488192443 325 NLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNN 388
Cdd:PLN03098   80 NLGLSLFSKGRVKDALAQFETALELNPNPDEAQAAYYNKACCHAYREEGKKAADCLRTALRDYN 143
TPR_12 pfam13424
Tetratricopeptide repeat;
189-280 6.56e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 35.44  E-value: 6.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 189 VQIGKCYYRLGMYREAEKQFKSALKQQEmvdtflylakvyvsldqpvtalnlfKQGLDKFPGEVTLLCGIARIYEEMNNM 268
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIAR-------------------------RLLGPDHPLTATTLLNLGRLYLELGRY 61

                          90
                  ....*....|..
gi 1488192443 269 SSAAEYYKEVLK 280
Cdd:pfam13424  62 EEALELLERALA 73
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 295-393 7.59e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.12  E-value: 7.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192443 295 NHFYSDQPEIALRFYRRLLQM---GIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIG 371
Cdd:COG1729     2 ALLKAGDYDEAIAAFKAFLKRypnSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELG 81

                          90       100
                  ....*....|....*....|..
gi 1488192443 372 DTNLAHQCFRLALVNNNNHAEA 393
Cdd:COG1729    82 DYDKARATLEELIKKYPDSEAA 103
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
 336-413 9.50e-03

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 36.96  E-value: 9.50e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1488192443 336 YDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGH-VEQIGDL 413
Cdd:PRK02603   51 YAEALENYEEALKLEEDPNDRSYILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYHKRGEkAEEAGDQ 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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