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Conserved domains on  [gi|1483569506|ref|NP_001353211|]
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golgin subfamily B member 1 isoform 5 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1906-2778 2.36e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.36e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1906 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1975
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1976 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2048
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2049 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2125
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2126 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2203
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2204 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2281
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2282 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2358
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2359 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2430
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2431 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2510
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2511 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2590
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2591 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2670
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2671 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2746
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1483569506 2747 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2778
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1358-2185 2.71e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.71e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1358 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1437
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1438 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1514
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1515 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1594
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1595 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1674
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1675 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1754
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1755 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1834
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1835 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1908
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1909 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1988
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1989 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2067
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2068 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2147
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1483569506 2148 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 764-1538 7.08e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 7.08e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  764 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 843
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 923
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 1003
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1004 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1082
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1083 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1148
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1149 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1204
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1205 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1255
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1256 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1330
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1331 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1400
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1401 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1468
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1483569506 1469 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1538
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1024 1.77e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.77e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  190 QQLQEKEEFISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  270 EESLVGRaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHH 349
Cdd:TIGR02168  283 IEELQKE---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  350 LLEQFEQAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLE 429
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  430 DQLQQKSKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKL 509
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  510 SSQITLLEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLl 569
Cdd:TIGR02168  488 QARLDSLERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK- 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  570 emKEAQEEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEH 649
Cdd:TIGR02168  567 --QNELGRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALEL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  650 QSRTSEEISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEIS 724
Cdd:TIGR02168  638 AKKLRPGYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  725 NLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIH 804
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  805 SLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMD 884
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  885 QLLLEKKRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVS 961
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1483569506  962 SGLKQNYDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1024
Cdd:TIGR02168  932 EGLEVRIDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2459-3187 1.52e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.94  E-value: 1.52e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2459 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2528
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2529 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2602
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2603 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2665
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2666 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2729
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2730 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2801
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2802 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2881
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2882 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2961
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2962 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3041
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 3042 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAgplNIDVAPGAPQE 3121
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES---KRSELRRELEE 919

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506 3122 KNgvhrksdpEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3187
Cdd:TIGR02168  920 LR--------EKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-307 6.78e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 6.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKakltslnkyieemkaqggtvlpte 125
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA------------------------ 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  126 pQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQaQ 205
Cdd:COG1196    327 -ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE-E 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  206 LSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ 285
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          250       260
                   ....*....|....*....|..
gi 1483569506  286 ELTAAEQRNQILSQQLQQMEAE 307
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGF 506
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1906-2778 2.36e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.36e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1906 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1975
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1976 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2048
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2049 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2125
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2126 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2203
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2204 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2281
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2282 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2358
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2359 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2430
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2431 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2510
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2511 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2590
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2591 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2670
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2671 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2746
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1483569506 2747 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2778
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1358-2185 2.71e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.71e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1358 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1437
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1438 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1514
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1515 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1594
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1595 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1674
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1675 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1754
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1755 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1834
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1835 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1908
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1909 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1988
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1989 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2067
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2068 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2147
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1483569506 2148 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 764-1538 7.08e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 7.08e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  764 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 843
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 923
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 1003
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1004 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1082
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1083 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1148
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1149 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1204
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1205 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1255
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1256 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1330
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1331 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1400
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1401 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1468
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1483569506 1469 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1538
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1024 1.77e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.77e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  190 QQLQEKEEFISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  270 EESLVGRaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHH 349
Cdd:TIGR02168  283 IEELQKE---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  350 LLEQFEQAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLE 429
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  430 DQLQQKSKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKL 509
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  510 SSQITLLEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLl 569
Cdd:TIGR02168  488 QARLDSLERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK- 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  570 emKEAQEEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEH 649
Cdd:TIGR02168  567 --QNELGRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALEL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  650 QSRTSEEISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEIS 724
Cdd:TIGR02168  638 AKKLRPGYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  725 NLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIH 804
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  805 SLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMD 884
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  885 QLLLEKKRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVS 961
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1483569506  962 SGLKQNYDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1024
Cdd:TIGR02168  932 EGLEVRIDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1839-2384 1.47e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.47e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1839 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVtkmNLLNQQIQEELSRVTKLKE 1918
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1919 TAEEEKDDLEeRLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1998
Cdd:COG1196    310 RRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1999 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2078
Cdd:COG1196    389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2079 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALR 2154
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAAL 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2155 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2234
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2235 EDNC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHS 2307
Cdd:COG1196    629 AARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506 2308 SQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLhEEINM 2384
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL-GPVNL 784
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1375-1942 2.32e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.51  E-value: 2.32e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1375 LQQKLESSQLQIAGLeHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1454
Cdd:COG1196    218 LKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1455 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1534
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1535 QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEstewQEKHK 1614
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1615 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE------KQLQEAEQEMEEMKEKMRKFAK 1688
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1689 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM----------SEKDSLS 1758
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGaigaavdlvaSDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1759 EEVQDLKHQIEGNVSKQANLEATEKHDNQTN-----VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKD 1833
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlreVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1834 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1913
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1483569506 1914 TKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1942
Cdd:COG1196    773 EREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2459-3187 1.52e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.94  E-value: 1.52e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2459 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2528
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2529 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2602
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2603 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2665
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2666 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2729
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2730 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2801
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2802 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2881
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2882 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2961
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2962 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3041
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 3042 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAgplNIDVAPGAPQE 3121
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES---KRSELRRELEE 919

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506 3122 KNgvhrksdpEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3187
Cdd:TIGR02168  920 LR--------EKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 764-1125 3.66e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 3.66e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  764 VTELRAQVKQLEmnlAEAERQRRldYesqtahdnllteqihsLSIEAKSKDVKIEVLQNELDDVQLQfseqstlIRSLQS 843
Cdd:COG1196    195 LGELERQLEPLE---RQAEKAER--Y----------------RELKEELKELEAELLLLKLRELEAE-------LEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 923
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRkLQAA 1003
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-LEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1004 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEysekcvtskcqeieiylkqtisEKEVELQHIRK 1083
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA----------------------ELEEEEEALLE 463

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1483569506 1084 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1125
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1500-2093 1.03e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 1.03e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1500 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD---RSLLENQSLSSSCES 1576
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1577 LKLALEGLTEDKEKL---VKEIESLKSSKIAESTEWQEKHKELQ------KEYEILLQSYENVSNEAERIQHVVEAVRQE 1647
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1648 KQELYGKLRstEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPagdtakecmetllssna 1727
Cdd:PRK03918   323 INGIEERIK--ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG----------------- 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1728 smkEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvSKQANLEATEKHDNQTNV-----TEEGTQSIPGET 1802
Cdd:PRK03918   384 ---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK---ELKKAIEELKKAKGKCPVcgrelTEEHRKELLEEY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1803 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKEriagLEEE-KQKNKEFSQTLENEKNTLLSQ 1881
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE----LEEKlKKYNLEELEKKAEEYEKLKEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1882 ISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLES 1961
Cdd:PRK03918   534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYN 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1962 EMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKI 2040
Cdd:PRK03918   603 EYLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSREL 675

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1483569506 2041 SALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2093
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 640-1235 4.93e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 4.93e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  640 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 719
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  720 AKEISNLNQLIEEFKKNADNNssaftaLSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLL 799
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDK------IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  800 TEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL-------EGAERVRHISSKVEELSQA 872
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  873 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 952
Cdd:pfam15921  477 LRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  953 QVEEDNEVSSGLKQNYDEMSP----------AGQISKEELQ----------HEFDLLKKENEQRKRKLQAAL----INRK 1008
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEkeindrrlelQEFKILKDKKDAKIRELEARVsdleLEKV 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1009 ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY---LKQTISEKEVELQHIRKDL 1085
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTL 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1086 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEisenqaiIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1165
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK-------IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1166 ELEEKILALEkekeqlQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1235
Cdd:pfam15921  789 AGELEVLRSQ------ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPG 852
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1844-2344 8.43e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.09  E-value: 8.43e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1844 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLKETAEEE 1923
Cdd:PRK03918   230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1924 KDDLEERLMNQLAELNGsIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE------EEKQQLVKEKTKVESEIRKEYLE 1997
Cdd:PRK03918   309 LREIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTPE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1998 KIQGAQKEPGNKShaKELQELLKEKQQEVKQLQKDCIRYQEKISALER------------TVKALEFVQTESQKDLEITK 2065
Cdd:PRK03918   388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2066 ENLAQAVEHRKKAQAELASFKVLLddtqsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2145
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2146 MQ------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL----QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2215
Cdd:PRK03918   541 IKslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2216 werkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHdkqiweskaqtevqlqqkvcdtlqgenkell 2295
Cdd:PRK03918   621 --------LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY------------------------------- 661

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1483569506 2296 sqlEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2344
Cdd:PRK03918   662 ---EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 48-613 9.39e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 9.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   48 EDVQERLAyaeqlvvELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:COG1196    182 EATEENLE-------RLEDILGELERQL----EPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  208 QTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 287
Cdd:COG1196    331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  288 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKL--SFHNLQEEMHHLLEQFEQAGQAQAELE 365
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALleLLAELLEEAALLEAALAELLEELAEAA 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  366 SRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQA---------VQSAQTIQQLEDQLQQKS 436
Cdd:COG1196    491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAlaaalqnivVEDDEVAAAAIEYLKAAK 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  437 KEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELK--AENEKLSSQIT 514
Cdd:COG1196    571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRraVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  515 LLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEAD 594
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570
                   ....*....|....*....
gi 1483569506  595 HEVLDQKEMKQMEGEGIAP 613
Cdd:COG1196    731 EAEREELLEELLEEEELLE 749
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1306-2184 4.55e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 4.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1306 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1385
Cdd:pfam02463  161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1386 IagLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1465
Cdd:pfam02463  241 L--LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1466 LCEMKQKpeeigeesrakqqIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1545
Cdd:pfam02463  319 SEKEKKK-------------AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1546 LALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1625
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1626 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1705
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1706 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1785
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1786 NQTNVTEEGTQSIPGETEEQDSLSMstrptcsesVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1865
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRK---------GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1866 EFSQTLENEKNTLLSQISTKDGELKMLQEEVT-KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1944
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQeAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1945 YCQDVTDAQIKNElLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepgnKSHAKELQELLKEKQQ 2024
Cdd:pfam02463  777 AEEREKTEKLKVE-EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK--------EEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2025 EVKQLQKDCIRYQEKISALERTVKALEfvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL 2104
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLL----KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2105 KLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2184
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2643-2946 9.29e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 9.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2643 EEEVHRLSALFSSSQKRIAELEEelvcvQKEAAKKVGEIEDKLKK--------ELKHLHHDAGIMRNETETAEERVAELA 2714
Cdd:COG1196    185 EENLERLEDILGELERQLEPLER-----QAEKAERYRELKEELKEleaellllKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2715 RDLVEME-------QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2787
Cdd:COG1196    260 AELAELEaeleelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2788 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR----KS 2863
Cdd:COG1196    340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerleRL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2864 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEEL 2943
Cdd:COG1196    420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499


                   ...
gi 1483569506 2944 RQE 2946
Cdd:COG1196    500 EAD 502
PTZ00121 PTZ00121
MAEBL; Provisional
 707-1234 2.82e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.82e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  707 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQ 784
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  785 RRLDYESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 857
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  858 RVRHISSKVEELSQA--LSQKELEITKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 933
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  934 KTLKEqlnlLSRAEEAKKEQVEEDNEVssglKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1013
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1014 VSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE 1093
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1094 QFQAlvKQMNQTLQDKTNQIDLLQAEISENQaiiqklitsntdasdgdsvalvketvvisppctgssehwKPELEEKILA 1173
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1483569506 1174 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1234
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1952-2708 7.52e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 7.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1952 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2031
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2032 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2111
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2112 SNKESVKSQMKQKDEDLERRL------EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2186 dstvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHD 2265
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2266 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK--DQLTDLSNSLEKCKEQKGNL 2343
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2344 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS 2423
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2424 QEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLI 2503
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2504 QEAAAE--NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKL 2581
Cdd:pfam02463  727 VQEAQDkiNEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2582 KESEEANEDLRRSFNALQE-EKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEvhrlsalfsSSQKRI 2660
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEqEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQE---------LLLKEE 877

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1483569506 2661 AELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEE 2708
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE 925
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 35-621 4.44e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 4.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   35 HQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEM 114
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  115 KAQG--------------------------------GTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHK-LQEKEELIS 161
Cdd:pfam15921  155 EAAKclkedmledsntqieqlrkmmlshegvlqeirSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKiLRELDTEIS 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  162 TLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEK-EEFISTLQAQLS------QTQAEQAAQLSSMQQVVREKDARFETQ 234
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRiEQLISEHEVEITgltekaSSARSQANSIQSQLEIIQEQARNQNSM 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  235 VRLHEDELLQLVTQadVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 314
Cdd:pfam15921  315 YMRQLSDLESTVSQ--LRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  315 VETEREESKILLEK-----MELEVAERKLSFHNLQ-EEMHHLLEQFEQagQAQAELESRYSALEQKHKAeMEEKTSHILS 388
Cdd:pfam15921  393 LSLEKEQNKRLWDRdtgnsITIDHLRRELDDRNMEvQRLEALLKAMKS--ECQGQMERQMAAIQGKNES-LEKVSSLTAQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  389 LQKTGQELQSACDALKDQnsKLLQDKNEQAVQS-AQTIQQLEDQLQQKSKEISQFLNRLPLQ----QHETASQTSFPDVY 463
Cdd:pfam15921  470 LESTKEMLRKVVEELTAK--KMTLESSERTVSDlTASLQEKERAIEATNAEITKLRSRVDLKlqelQHLKNEGDHLRNVQ 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  464 NE---------GTQAVTE---ENIASLQKRVVELENEKGALLLSS-----------IELEELKAENEKLSSQITLLEAQn 520
Cdd:pfam15921  548 TEcealklqmaEKDKVIEilrQQIENMTQLVGQHGRTAGAMQVEKaqlekeindrrLELQEFKILKDKKDAKIRELEAR- 626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  521 rtgEADREVSEISIVDIANKRSSSAEESGQ--DVLENTFSQKHKELSVLLLEM---------KEAQEEIAFLKLQLQGKR 589
Cdd:pfam15921  627 ---VSDLELEKVKLVNAGSERLRAVKDIKQerDQLLNEVKTSRNELNSLSEDYevlkrnfrnKSEEMETTTNKLKMQLKS 703

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1483569506  590 AEEADHEVldQKEMKQMEGEGIAPIKMKVFLE 621
Cdd:pfam15921  704 AQSELEQT--RNTLKSMEGSDGHAMKVAMGMQ 733
PRK11281 PRK11281
mechanosensitive channel MscK;
151-513 9.70e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.84  E-value: 9.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  151 HKLQEKEEliSTLQAQLTQAQA--EQPAQSSTEMEEfvmMKQQLQEkeefistLQAQLSQTQAEQAAQLSSMQQVVREkd 228
Cdd:PRK11281    51 QKLLEAED--KLVQQDLEQTLAllDKIDRQKEETEQ---LKQQLAQ-------APAKLRQAQAELEALKDDNDEETRE-- 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  229 aRFETqvrLHEDELLQLVTQadVETEMQQklrvLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEH 308
Cdd:PRK11281   117 -TLST---LSLRQLESRLAQ--TLDQLQN----AQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGG 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  309 NTLRNTVETERE------ESKILLEKMELEVAERKLSFHNLQeemHHLLEqfEQAGQAQAELESRYSALEQKHKAEMEek 382
Cdd:PRK11281   187 KALRPSQRVLLQaeqallNAQNDLQRKSLEGNTQLQDLLQKQ---RDYLT--ARIQRLEHQLQLLQEAINSKRLTLSE-- 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  383 tshilslqKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQT-IQQLE--DQLQQKSKEISQFLNRlpLQQhetasqtsf 459
Cdd:PRK11281   260 --------KTVQEAQSQDEAARIQANPLVAQELEINLQLSQRlLKATEklNTLTQQNLRVKNWLDR--LTQ--------- 320

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1483569506  460 pdvynegTQAVTEENIASLQkrvvelenekGALLLSSIELEELKA-----ENEKLSSQI 513
Cdd:PRK11281   321 -------SERNIKEQISVLK----------GSLLLSRILYQQQQAlpsadLIEGLADRI 362
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1829-2067 5.66e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 5.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1829 AVSKDFSSHDEINNYLQQIDQLKERIAgleeEKQKNKEFSQTLENEKNTLLSQISTKDGELkmlqeEVTKMNLLNQQIQE 1908
Cdd:NF012221  1536 ATSESSQQADAVSKHAKQDDAAQNALA----DKERAEADRQRLEQEKQQQLAAISGSQSQL-----ESTDQNALETNGQA 1606

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1909 ELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGN-YCQDVTDAQIKNelLESEMKNLKKCVSE-LEEEKQQLVKEK 1984
Cdd:NF012221  1607 QRDAILEESRAVTKELTTLAQGLdaLDSQATYAGESGDqWRNPFAGGLLDR--VQEQLDDAKKISGKqLADAKQRHVDNQ 1684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1985 TKVESEIRKEYLEKIQGAQKEPG-------NKSHAKELQELLKEKQQEVKQLQKDC-IRYQEKISALERTVKALEFVQTE 2056
Cdd:NF012221  1685 QKVKDAVAKSEAGVAQGEQNQANaeqdiddAKADAEKRKDDALAKQNEAQQAESDAnAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|.
gi 1483569506 2057 SQKDLEITKEN 2067
Cdd:NF012221  1765 AQADAKGAKQD 1775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-307 6.78e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 6.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKakltslnkyieemkaqggtvlpte 125
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA------------------------ 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  126 pQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQaQ 205
Cdd:COG1196    327 -ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE-E 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  206 LSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ 285
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          250       260
                   ....*....|....*....|..
gi 1483569506  286 ELTAAEQRNQILSQQLQQMEAE 307
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGF 506
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2042-2211 6.99e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 41.52  E-value: 6.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2042 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2117
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2118 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2174
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1483569506 2175 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2211
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1906-2778 2.36e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.36e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1906 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1975
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1976 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2048
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2049 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2125
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2126 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2203
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2204 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2281
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2282 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2358
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2359 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2430
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2431 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2510
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2511 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2590
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2591 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2670
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2671 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2746
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1483569506 2747 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2778
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1358-2185 2.71e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.71e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1358 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1437
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1438 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1514
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1515 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1594
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1595 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1674
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1675 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1754
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1755 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1834
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1835 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1908
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1909 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1988
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1989 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2067
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2068 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2147
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1483569506 2148 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1307-2092 4.50e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.05  E-value: 4.50e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1307 TSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGL-EIESLKTVSHEAEVHAESLQQKLESSQLQ 1385
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1386 iaglehLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1462
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1463 QVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARGTIERLTKSLADVESQ 1531
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1532 VSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGL--------------------------- 1584
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtvaqlgsvgeryataievaagnrln 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1585 ---TEDKEKLVKEIESLKSSKIAEST-----EWQEKHKELQKEYE-----ILL------QSYENVSNEAERIQHVVEAVr 1645
Cdd:TIGR02169  551 nvvVEDDAVAKEAIELLKRRKAGRATflplnKMRDERRDLSILSEdgvigFAVdlvefdPKYEPAFKYVFGDTLVVEDI- 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1646 QEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMrkFAKSKQQKILELEEENDRLRAEVhpagdtakecmetllss 1725
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGIL--FSRSEPAELQRLRERLEGLKREL----------------- 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1726 nASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEatekhdnqtnvteegtqsipgetEEQ 1805
Cdd:TIGR02169  691 -SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE-----------------------EDL 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1806 DSLSmstrptcsesvpsaksanpavskdfsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTllSQISTK 1885
Cdd:TIGR02169  747 SSLE----------------------------QEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEI 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1886 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKN 1965
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1966 LKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR---------- 2035
Cdd:TIGR02169  873 LEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeels 952

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2036 ---YQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDT 2092
Cdd:TIGR02169  953 ledVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 764-1538 7.08e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 7.08e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  764 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 843
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 923
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 1003
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1004 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1082
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1083 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1148
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1149 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1204
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1205 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1255
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1256 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1330
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1331 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1400
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1401 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1468
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1483569506 1469 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1538
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 768-1651 2.02e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 2.02e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  768 RAQVKQLEMNLAEAERQ-RRLDYESQTAHDNL-LTEQIHSLSIEAKSKDvkIEVLQNELDDVQLQFSEQSTLIRSLQSQL 845
Cdd:TIGR02168  185 RENLDRLEDILNELERQlKSLERQAEKAERYKeLKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  846 QNKESEvlegaervrhisskveelsqaLSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLNEE 925
Cdd:TIGR02168  263 QELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  926 KFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAgqisKEELQHEFDLLKKENEQRKRKLQAALI 1005
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1006 NRKELLQRVSRLEEELANLKDESKKEiplsETERGEVEEDKENKEYSEkcvtskcqeieiyLKQTISEKEVELQHIRKDL 1085
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQEEL 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1086 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASdgdSVALVKETVVISPPCTGSSEHWKP 1165
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK---ALLKNQSGLSGILGVLSELISVDE 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1166 ELEEKILALekekeqLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIGDQL 1238
Cdd:TIGR02168  534 GYEAAIEAA------LGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAKDL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1239 RQLQIQVRESIDGKLpstdqqescsSTPGLEEPLFKATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQIKA 1314
Cdd:TIGR02168  608 VKFDPKLRKALSYLL----------GGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1315 QLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE 1394
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1395 lqpkldELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALhtqlemqakehDERIKQLQVELCEMKqkpE 1474
Cdd:TIGR02168  758 ------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL-----------REALDELRAELTLLN---E 817

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1475 EIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERD 1554
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE 897

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1555 KLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEstewqekhkELQKEYEILLQSYENVSNEA 1634
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIEDDE 967

                          890
                   ....*....|....*..
gi 1483569506 1635 ERIQHVVEAVRQEKQEL 1651
Cdd:TIGR02168  968 EEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2021-2789 2.16e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 2.16e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2021 EKQQEVKQLQKDC----IRYQEKISALERTVKALEFVQTESQkdLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEA 2096
Cdd:TIGR02168  199 ERQLKSLERQAEKaeryKELKAELRELELALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2097 ARVLADNLKLKKELQSnkesvksqMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDK 2176
Cdd:TIGR02168  277 SELEEEIEELQKELYA--------LANEISRLEQQKQILRER----LANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2177 EVQQLQENLDStvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEirlkedncSVLKDQLRQMSIHMEELK 2256
Cdd:TIGR02168  345 KLEELKEELES---LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2257 INISRLEHDKQIWESKAQ-TEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEK 2335
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2336 CKEQKGNLEGIIRQQEADIQN-SKFSY------EQLETDLQASRELTSRLHEEINM-------KEQKIISLLSgKEEAIQ 2401
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNqSGLSGilgvlsELISVDEGYEAAIEAALGGRLQAvvvenlnAAKKAIAFLK-QNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2402 VAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETL--KTIKKENIQQKAQL--------------- 2464
Cdd:TIGR02168  573 VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNALELakklrpgyrivtldg 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2465 -------------DSFVKSMSSLQNDRDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSEN 2531
Cdd:TIGR02168  653 dlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEK----IAELEKALAELRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2532 AKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQN-------------KELENKYAKLEEKLKESEEANEDLRRSFNAL 2598
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2599 QEEKQDLSKEIESLKVSISQLTRQVTALQEEgtLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqkeaaKKV 2678
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERR--LEDLEEQIEELSEDIESLAAEIEELEELIEELESEL--------EAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2679 GEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFgrsmssLQNSRDHANEE 2758
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL------QERLSEEYSLT 952

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1483569506 2759 LDELKRKYDASLKELAQLKEQ-GLLNRERDAL 2789
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRlKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1311-2192 7.73e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 7.73e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1311 QIKAQLKEIE-----AEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1385
Cdd:TIGR02168  217 ELKAELRELElallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1386 IAGLEH-LRELQPKLDELQKLISKKEEdvsylsgQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQv 1464
Cdd:TIGR02168  297 ISRLEQqKQILRERLANLERQLEELEA-------QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE- 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1465 elcEMKQKPEEigeesrakqqiqrkLQAALISRKEALKEnksLQEELSLARGTIERLTKSLADVESqvsaqnkekdtvlg 1544
Cdd:TIGR02168  369 ---ELESRLEE--------------LEEQLETLRSKVAQ---LELQIASLNNEIERLEARLERLED-------------- 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1545 RLALLQEERDKLITEMDRSllENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQkEYEILL 1624
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1625 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1704
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1705 RAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLkhqiegnvsKQANLEATEKH 1784
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDL---------DNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1785 DNQTNVTEEGTQSIPGETeeqdslsmstrptcsesvpSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKN 1864
Cdd:TIGR02168  643 PGYRIVTLDGDLVRPGGV-------------------ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1865 KEFSQTLENEKNTLLSQISTKDGELKMLQEEV----TKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQLAELNG 1940
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLarleAEVEQLEERIAQLSKELTELEAEIEELEERLEE-AEEELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1941 SIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLK 2020
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2021 EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT-------KENLAQAVEHRKKAQAELASFKVLLDDTQ 2093
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskrselRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2094 SEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ---------AEEKHLKEKKN-MQEKLDALRREKVHLEET 2163
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaaiEEYEELKERYDfLTAQKEDLTEAKETLEEA 1022

                          890       900       910
                   ....*....|....*....|....*....|
gi 1483569506 2164 IGEI-QVTLNKKDKEVQQLQENLDSTVTQL 2192
Cdd:TIGR02168 1023 IEEIdREARERFKDTFDQVNENFQRVFPKL 1052
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2124-2960 8.55e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 8.55e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2124 KDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLN------KKDKEVQQLQENLDSTvtQLAAF 2195
Cdd:TIGR02168  153 KPEERRAIFEEAAgiSKYKERRKETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELREL--ELALL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2196 TKSMSSLQDDRDRVIDEAKKWERKFSDA---IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK 2272
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELtaeLQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2273 AQTEVQLQQKVCDTLQgenkELLSQLEETrhlyhssQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2352
Cdd:TIGR02168  311 LANLERQLEELEAQLE----ELESKLDEL-------AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2353 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQ----VAIAELRQQHDKEIKELENLLSQEeee 2428
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKkleeAELKELQAELEELEEELEELQEEL--- 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2429 nivleeenkkavdktNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsiilekdqlIQEAAA 2508
Cdd:TIGR02168  457 ---------------ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG------------FSEGVK 509

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2509 ENNKLKEEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEA 2587
Cdd:TIGR02168  510 ALLKNQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGN 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2588 NEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQV-------TALQ-----------------------------EEGT 2631
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddldNALElakklrpgyrivtldgdlvrpggvitggsAKTN 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2632 LGLYHAQLKVKE--EEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETETAEER 2709
Cdd:TIGR02168  670 SSILERRREIEEleEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL-SRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2710 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDAL 2789
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2790 LSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqr 2869
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELS-------- 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2870 saaqpstspAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELhpLKAQLQEYQDKTKAFQIMQEELRQENLS 2949
Cdd:TIGR02168  901 ---------EELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEE 969

                          890
                   ....*....|.
gi 1483569506 2950 WQHELHQLRME 2960
Cdd:TIGR02168  970 ARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1309-2178 2.42e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 83.19  E-value: 2.42e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1309 VAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQgLEIESLKTVSHEAEVHA-----ESLQQKLESSQ 1383
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEGYEllkekEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1384 LQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEK-EAALTKIQTEIIEQEDLIKALHTQL---EMQAKEHDER 1458
Cdd:TIGR02169  244 RQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIaekERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1459 IKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEalkenkslqeELSLARGTIERLTKSLADVESQVSAQNKE 1538
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE----------ELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1539 KDTvlgrlalLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDkeklVKEIESLKSSKIAESTEWQEKHKELQK 1618
Cdd:TIGR02169  394 LEK-------LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK----INELEEEKEDKALEIKKQEWKLEQLAA 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1619 EYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELE 1698
Cdd:TIGR02169  463 DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1699 -EENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVqDLKHQIEgNVSKQA- 1776
Cdd:TIGR02169  543 vAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLV-EFDPKYE-PAFKYVf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1777 -------NLEATEKH-DNQTNVTEEGtqsipgeteeqDSLSMSTRPTCSESVPSAKSANPAvskdfsshdeinNYLQQID 1848
Cdd:TIGR02169  621 gdtlvveDIEAARRLmGKYRMVTLEG-----------ELFEKSGAMTGGSRAPRGGILFSR------------SEPAELQ 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1849 QLKERIAGLEEEKQKNKEFSQTLENEKNTLLS-------QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1921
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIENRLDELSQelsdasrKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1922 EEKDDLEERlmnqLAELNGSIGNYCQDVTDaqIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG 2001
Cdd:TIGR02169  758 SELKELEAR----IEELEEDLHKLEEALND--LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2002 AQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAE 2081
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2082 LASFKVLLDDTQsEAARVLADNLK----LKKELQSNKESVKS--QMKQKDEDLERRLEQAE----------EKHLKEKKN 2145
Cdd:TIGR02169  912 IEKKRKRLSELK-AKLEALEEELSeiedPKGEDEEIPEEELSleDVQAELQRVEEEIRALEpvnmlaiqeyEEVLKRLDE 990

                          890       900       910
                   ....*....|....*....|....*....|...
gi 1483569506 2146 MQEKLDALRREKVHLEETIGEiqvtLNKKDKEV 2178
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEE----YEKKKREV 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1837-2534 4.32e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.32e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1837 HDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKL 1916
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1917 KETAEEEKDDLEERLMNQLAELNGS---IGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1993
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1994 EYLE-KIQGAQKEPGNKSHAKELQELLK-EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTEsqkdLEITKENLAQA 2071
Cdd:TIGR02168  398 LNNEiERLEARLERLEDRRERLQQEIEElLKKLEEAELKELQAELEELEEELEELQEELERLEEA----LEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2072 VEHRKKAQAELASFKVLLDDTQSEAARVL-----ADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK----E 2142
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEgfsegVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavvvE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2143 KKNMQEK-LDALRREKVH----LEETI---GEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSL------QDDRDR 2208
Cdd:TIGR02168  554 NLNAAKKaIAFLKQNELGrvtfLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2209 VIDEAKKW-----------------------ERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLE-- 2263
Cdd:TIGR02168  634 ALELAKKLrpgyrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEee 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2264 ---------------HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTD 2328
Cdd:TIGR02168  714 leqlrkeleelsrqiSALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2329 LSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLlsgkeeaiQVAIAELR 2408
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL--------AAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2409 QQHDKEIKELENLLSQEEEENIVLEEENKKAvdktNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2488
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1483569506 2489 EERhlsiILEKDQLIQEAAAEN-NKLKEEIRGLRSHMDDLNSENAKL 2534
Cdd:TIGR02168  942 QER----LSEEYSLTLEEAEALeNKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 190-1024 1.77e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.77e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  190 QQLQEKEEFISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 269
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  270 EESLVGRaqvVDLLQQELTAAEQRNQILSQQLQQMEAEhntlRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHH 349
Cdd:TIGR02168  283 IEELQKE---LYALANEISRLEQQKQILRERLANLERQ----LEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  350 LLEQFEQAGQAQAELESRYSALEQKHkaemeektshilslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLE 429
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQL------------------ETLRSKVAQLELQIASL----NNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  430 DQLQQKSKEISQFLNRLPLQQHETASQTSfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKL 509
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAEL------EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  510 SSQITLLEA-QNRTGEADREVSEI---------------SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLl 569
Cdd:TIGR02168  488 QARLDSLERlQENLEGFSEGVKALlknqsglsgilgvlsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK- 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  570 emKEAQEEIAFLKLQLQGKRAEEADHEVLdQKEMKQMEGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEH 649
Cdd:TIGR02168  567 --QNELGRVTFLPLDSIKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALEL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  650 QSRTSEEISLNDAGVELKS-----TKQDGDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEIS 724
Cdd:TIGR02168  638 AKKLRPGYRIVTLDGDLVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  725 NLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIH 804
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  805 SLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMD 884
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  885 QLLLEKKRDVETLQQTIEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVS 961
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1483569506  962 SGLKQNYDEMspAGQISkEELQHEFDLLKKENEQRKRKLQaalinrkELLQRVSRLEEELANL 1024
Cdd:TIGR02168  932 EGLEVRIDNL--QERLS-EEYSLTLEEAEALENKIEDDEE-------EARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1843-2626 1.38e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.40  E-value: 1.38e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1843 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEE 1922
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1923 EKDDLEerlmNQLAELNGSIgnycqdvtdaqiknELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEylekiqgA 2002
Cdd:TIGR02168  310 RLANLE----RQLEELEAQL--------------EELESKLDELAEELAELEEKLEELKEELESLEAELEEL-------E 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2003 QKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqTESQKDLEITKENLAQAVEHRKKA-QAE 2081
Cdd:TIGR02168  365 AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DRRERLQQEIEELLKKLEEAELKElQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2082 LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKS------QMKQKDEDLERRLEQAEEKHLKEKKNMQEKLD---- 2151
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAaerelaQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgi 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2152 -ALRREKVH--------LEETIGE-----IQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRD---------- 2207
Cdd:TIGR02168  522 lGVLSELISvdegyeaaIEAALGGrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDReilkniegfl 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2208 RVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLkDQLRQM------------------SIHMEELKINISRLEHDKQIW 2269
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNAL-ELAKKLrpgyrivtldgdlvrpggVITGGSAKTNSSILERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2270 ESKAQtevqlqqkvCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ 2349
Cdd:TIGR02168  681 ELEEK---------IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2350 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2429
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI--------EQLKEELKALREALDELRAELTLLNEEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2430 IVLEEENKKAVDKTNQLMETLKTIKKENIQQK---AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL---I 2503
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIEslaAEIEELEELIEELESELEALLNERASLEEALALLRSELEELseeL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2504 QEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLN--QVITIKDSQQKQLLEVQLQQN-----KELENKYAK 2576
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSeeYSLTLEEAEALENKIEDDEEEarrrlKRLENKIKE 983

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2577 LEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2626
Cdd:TIGR02168  984 LGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1839-2384 1.47e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.47e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1839 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVtkmNLLNQQIQEELSRVTKLKE 1918
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1919 TAEEEKDDLEeRLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1998
Cdd:COG1196    310 RRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1999 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2078
Cdd:COG1196    389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2079 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALR 2154
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAAL 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2155 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2234
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2235 EDNC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHS 2307
Cdd:COG1196    629 AARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506 2308 SQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLhEEINM 2384
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL-GPVNL 784
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1375-1942 2.32e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.51  E-value: 2.32e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1375 LQQKLESSQLQIAGLeHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1454
Cdd:COG1196    218 LKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1455 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1534
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1535 QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEstewQEKHK 1614
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEA 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1615 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE------KQLQEAEQEMEEMKEKMRKFAK 1688
Cdd:COG1196    453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGV 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1689 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM----------SEKDSLS 1758
Cdd:COG1196    533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGaigaavdlvaSDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1759 EEVQDLKHQIEGNVSKQANLEATEKHDNQTN-----VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKD 1833
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlreVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1834 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1913
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1483569506 1914 TKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1942
Cdd:COG1196    773 EREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1311-1600 7.64e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 7.64e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1311 QIKAQLKEIEAEKVELELKvssttsELTKKSEEvfqLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL- 1389
Cdd:COG1196    217 ELKEELKELEAELLLLKLR------ELEAELEE---LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAq 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1390 EHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1469
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1470 KQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALL 1549
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1483569506 1550 QEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS 1600
Cdd:COG1196    448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 799-1769 8.06e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 8.06e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  799 LTEQIHSLSIEAKsKDVKIEVLQNELDDVQLQFSEQStlIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKEL 878
Cdd:TIGR02168  198 LERQLKSLERQAE-KAERYKELKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  879 EITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDN 958
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  959 EVSSGLKQNYDEMSPAgqisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEiplsETE 1038
Cdd:TIGR02168  351 EELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL----QQE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1039 RGEVEEDKENKEYSEkcvtskcqeieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQA 1118
Cdd:TIGR02168  423 IEELLKKLEEAELKE-------------LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1119 EISENQAIIQKLITSNTDASdgdSVALVKETVVISPPCTGSSEHWKPELEEKILALekekeqLQKKLQEALTSRKAILKK 1198
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVK---ALLKNQSGLSGILGVLSELISVDEGYEAAIEAA------LGGRLQAVVVENLNAAKK 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1199 AQEkerhlreelkqqkddynrlqeqFDEQSKenenigdqLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLfkateq 1278
Cdd:TIGR02168  561 AIA----------------------FLKQNE--------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA------ 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1279 hhtqpvleSNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTseltkkseevfqlqEQINKQGLei 1358
Cdd:TIGR02168  605 --------KDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDG--------------DLVRPGGV-- 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1359 eslkTVSHEAEVHAESLQQKLEssqlqiaglehLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQE 1438
Cdd:TIGR02168  661 ----ITGGSAKTNSSILERRRE-----------IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1439 DLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqaalisrKEALKENKSLQEELSLARGTI 1518
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-------AEAEAEIEELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1519 ERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESL 1598
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1599 ksskiaestewQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEkqlqeaeqemee 1678
Cdd:TIGR02168  879 -----------LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE------------ 935

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1679 mkekmrkfakskqqkiLELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKM--------------EYETLS 1744
Cdd:TIGR02168  936 ----------------VRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaaieEYEELK 999

                          970       980
                   ....*....|....*....|....*
gi 1483569506 1745 KKFQSLMSEKDSLSEEVQDLKHQIE 1769
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTEAKETLEEAIE 1024
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2459-3187 1.52e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.94  E-value: 1.52e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2459 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2528
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2529 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2602
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2603 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2665
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2666 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2729
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2730 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2801
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2802 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2881
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2882 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2961
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2962 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3041
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 3042 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAgplNIDVAPGAPQE 3121
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELES---KRSELRRELEE 919

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506 3122 KNgvhrksdpEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3187
Cdd:TIGR02168  920 LR--------EKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1970-2794 2.32e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.56  E-value: 2.32e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1970 VSELEEEKQQLVKEKTKVESEIRKEYL---EKIQGAQKEPGNKSHAKELQELLKEKQQ-EVKQLQKDCIRYQEKISALER 2045
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2046 TVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAsfkvllDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKD 2125
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK------DLGEEEQLRVKEKIGELEAEIASLERSIAEK-EREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2126 EDLERRLEQAEE---KHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK-------KDKEVQQLQENLDSTVTQLAAF 2195
Cdd:TIGR02169  318 EDAEERLAKLEAeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDlraeleeVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2196 TKSMSSLQDDRDRVIDEAKKWERKFSDAiqskEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQT 2275
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADL----NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2276 EVQLQQKVCDTLQGENKElLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQ---------KGNLEGI 2346
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRE-LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaaGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2347 IRQQEADIQN----------SKFSYEQLeTDLQASRELTSRLHE-----------EINMKEQKII-----------SLLS 2394
Cdd:TIGR02169  553 VVEDDAVAKEaiellkrrkaGRATFLPL-NKMRDERRDLSILSEdgvigfavdlvEFDPKYEPAFkyvfgdtlvveDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2395 GKEEAIQVAIAELrqqhDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEniqqkaqLDSFVKSMSSL 2474
Cdd:TIGR02169  632 ARRLMGKYRMVTL----EGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRE-------LSSLQSELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2475 QNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE---EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITI 2551
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEleeDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2552 KDSQQKQLLEVQLQqnkELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-- 2629
Cdd:TIGR02169  781 LNDLEARLSHSRIP---EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEie 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2630 ---GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqKEAAKKVGEIEDKLKKELKHLhhdaGIMRNETETA 2706
Cdd:TIGR02169  858 nlnGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL----RELERKIEELEAQIEKKRKRL----SELKAKLEAL 929

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2707 EERVAELARDLVEMEQKLLMVTKENKgLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEqgllnrER 2786
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEE------ER 1002


                   ....*...
gi 1483569506 2787 DALLSETA 2794
Cdd:TIGR02169 1003 KAILERIE 1010
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1575-2383 9.14e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 9.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1575 ESLKLALegLTEDKEKLVKEIESLKSSKIAESTEW---QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQEL 1651
Cdd:TIGR02168  223 RELELAL--LVLRLEELREELEELQEELKEAEEELeelTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1652 YGKLRSTEANKKETEKQLQEAEQEMEEMkekmrkfakskQQKILELEEENDRLRAEVhpagDTAKECMETLLSSNASMKE 1731
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQLEEL-----------ESKLDELAEELAELEEKL----EELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1732 ELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEAtEKHDNQTNVTEEGTQSIPGETEEQDSLSMS 1811
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED-RRERLQQEIEELLKKLEEAELKELQAELEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1812 TRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQ----QIDQLKERIAGLEEEKQKNKEFSQTLENEKN----------T 1877
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDaaerELAQLQARLDSLERLQENLEGFSEGVKALLKnqsglsgilgV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1878 LLSQISTKDG---------ELKMLQEEVTKMNLLNQQI----QEELSRVTKLKETAEEEkDDLEERLMNQLAELNGSIGn 1944
Cdd:TIGR02168  525 LSELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIaflkQNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1945 YCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHA---------KEL 2015
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2016 QELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvlLDDTQSE 2095
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2096 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2175
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2176 KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWerkfSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2255
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2256 KINISRL-EHDKQIWESKAQTEVQLQQkvcdTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSN--- 2331
Cdd:TIGR02168  914 RRELEELrEKLAQLELRLEGLEVRIDN----LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnl 989

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1483569506 2332 -SLEKCKEQKGNLEgIIRQQEADIQNSKFSYEQLETDLqaSRELTSRLHEEIN 2383
Cdd:TIGR02168  990 aAIEEYEELKERYD-FLTAQKEDLTEAKETLEEAIEEI--DREARERFKDTFD 1039
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1170-1993 1.44e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 1.44e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1170 KILALEKEKEQLQKKLQEALTSRKAILKKAQEKErhlrEELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsi 1249
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-- 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1250 dgklpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASAlqggtSVAQIKAQLKEIEAEKVELELK 1329
Cdd:TIGR02168  307 --------LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE-----ELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1330 VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKK 1409
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-LKELQAELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1410 EEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMqAKEHDERIKQLQVELCEMKQKPEEI-GEESRAKQQIQR 1488
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLsGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1489 K--------------LQAALISRKEALKENKSLQEELSLARGTIERLT-KSLADVESQVSAQNKEKDTVLGRLALLQEER 1553
Cdd:TIGR02168  532 DegyeaaieaalggrLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDsIKGTEIQGNDREILKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1554 DKLITEMDRSLlenqSLSSSCESLKLALEGL----------TEDKEKL---------VKEIESLKSSKIAESTEWQEKHK 1614
Cdd:TIGR02168  612 PKLRKALSYLL----GGVLVVDDLDNALELAkklrpgyrivTLDGDLVrpggvitggSAKTNSSILERRREIEELEEKIE 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1615 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKI 1694
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1695 LELEEENDRLrAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvsk 1774
Cdd:TIGR02168  768 ERLEEAEEEL-AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----- 841

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1775 qanlEATEKHDNQTNVTEEGTQSIPGETEEQDSLsmstrptcsesvpsaksanpavskdfssHDEINNYLQQIDQLKERI 1854
Cdd:TIGR02168  842 ----DLEEQIEELSEDIESLAAEIEELEELIEEL----------------------------ESELEALLNERASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1855 AGLEEEKQKnkefsqtLENEKNTLLSQISTKDGELKMLQEEVTKMNL----LNQQIQEELSRVTKLKETAEEEKDDLEER 1930
Cdd:TIGR02168  890 ALLRSELEE-------LSEELRELESKRSELRRELEELREKLAQLELrlegLEVRIDNLQERLSEEYSLTLEEAEALENK 962

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1483569506 1931 LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1993
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 814-1655 1.99e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 1.99e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  814 DVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEvLEGAERVRHISSKVEELSQALSQKELEitKMDQLLLEKKRD 893
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEKE--ALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  894 VETLQQTIEEKDQQVTEISFSMTEKMVQLNE-----------EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSS 962
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEElnkkikdlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  963 GLKQNYDEMspagQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESK---KEIPLSETER 1039
Cdd:TIGR02169  326 KLEAEIDKL----LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKdyrEKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1040 GEVEEDKENKEYSEKCVTSKCQEIEIYLKQtISEKEVELQHIRKDLEEKLAAEE----QFQALVKQMNQTLQDKTNQIDL 1115
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAIAG-IEAKINELEEEKEDKALEIKKQEwkleQLAADLSKYEQELYDLKEEYDR 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1116 LQAEISENQAIIQKLITSNTDASD--GDSVALVKETVVISPPCTGSSEHWKPELEEKILALEK-----------EKEQLQ 1182
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEErvRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVaagnrlnnvvvEDDAVA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1183 KKLQEALTSRKA------ILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKE--NENIGDQL--------RQLQIQVR 1246
Cdd:TIGR02169  561 KEAIELLKRRKAgratflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafKYVFGDTLvvedieaaRRLMGKYR 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1247 E-SIDGKLpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESnLCPDWPSHSEDASALQGGTS-----VAQIKAQLKEIE 1320
Cdd:TIGR02169  641 MvTLEGEL----FEKSGAMTGGSRAPRGGILFSRSEPAELQR-LRERLEGLKRELSSLQSELRrienrLDELSQELSDAS 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1321 AEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHlRELQPKLD 1400
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA-RLSHSRIP 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1401 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIGEES 1480
Cdd:TIGR02169  795 EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI----DLKEQIKSIEKEIENLNGKKEELEEEL 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1481 RAKQQIQRKLQAALISRKealKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERdklitem 1560
Cdd:TIGR02169  871 EELEAALRDLESRLGDLK---KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK------- 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1561 dRSLLENQSLSSSCESLKLALEGLTEDKEKL----VKEIESLKSSKiAESTEWQEKHKELQKEYEILLQSYENVSNEAER 1636
Cdd:TIGR02169  941 -GEDEEIPEEELSLEDVQAELQRVEEEIRALepvnMLAIQEYEEVL-KRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018

                          890       900
                   ....*....|....*....|
gi 1483569506 1637 I-QHVVEAVRQEKQELYGKL 1655
Cdd:TIGR02169 1019 VfMEAFEAINENFNEIFAEL 1038
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2012-2612 2.75e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.97  E-value: 2.75e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2012 AKELQELLKEKQQEVKQLQKDciRYQEKISALERTVKALEfvqtesqkdleitkENLAQAVEHRKKAQAELASFKVLLDD 2091
Cdd:COG1196    215 YRELKEELKELEAELLLLKLR--ELEAELEELEAELEELE--------------AELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2092 TQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV 2169
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2170 TLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRvideakkwerkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMS 2249
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2250 IHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDL 2329
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2330 SNSLEKCKEQKGNLE-GIIRQQEADIQNSKFSYEQ-LETDLQASRELTSRLHEEInmkEQKIISLLSGKEEAiQVAIAEL 2407
Cdd:COG1196    504 EGFLEGVKAALLLAGlRGLAGAVAVLIGVEAAYEAaLEAALAAALQNIVVEDDEV---AAAAIEYLKAAKAG-RATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2408 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLktikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQ 2487
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL----LGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2488 LEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDsQQKQLLEVQLQQN 2567
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL-EEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1483569506 2568 KELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESL 2612
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 764-1125 3.66e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 3.66e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  764 VTELRAQVKQLEmnlAEAERQRRldYesqtahdnllteqihsLSIEAKSKDVKIEVLQNELDDVQLQfseqstlIRSLQS 843
Cdd:COG1196    195 LGELERQLEPLE---RQAEKAER--Y----------------RELKEELKELEAELLLLKLRELEAE-------LEELEA 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 923
Cdd:COG1196    247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRkLQAA 1003
Cdd:COG1196    327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-LEEL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1004 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEysekcvtskcqeieiylkqtisEKEVELQHIRK 1083
Cdd:COG1196    406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA----------------------ELEEEEEALLE 463

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1483569506 1084 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1125
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 48-930 4.94e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 4.94e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   48 EDVQERLAYAEQLVVELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQpaqsstemEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI--------SRLEQQKQILRERLANLERQLEELE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  208 QTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLvtqadveTEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 287
Cdd:TIGR02168  323 AQLEELESKLDELAEELAELEEKLEELKEELESLEAEL-------EELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  288 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREE-SKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELES 366
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  367 RYSALEQKHKAEMEEKTShILSLQKTGQELQSACDALKDQNSKLLQDKN------------EQAVQSA--QTIQQLEDQL 432
Cdd:TIGR02168  476 ALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGvlselisvdegyEAAIEAAlgGRLQAVVVEN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  433 QQKSKEISQFLnrlplQQHETASQTSFPdvynegtqaVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQ 512
Cdd:TIGR02168  555 LNAAKKAIAFL-----KQNELGRVTFLP---------LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSY 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  513 I--------TLLEAQNRTGEADREVSEISIV-DIANKRSSSAEESGQDVLeNTFSQKhKELSVLLLEMKEAQEEIAFLKL 583
Cdd:TIGR02168  621 LlggvlvvdDLDNALELAKKLRPGYRIVTLDgDLVRPGGVITGGSAKTNS-SILERR-REIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  584 QLQgkRAEEADHEVLDQKEMKQMEGEGIapikmkvfledtgqdfplmpNEESSLPAVEKEQASTEHQSRTSEEISLndag 663
Cdd:TIGR02168  699 ALA--ELRKELEELEEELEQLRKELEEL--------------------SRQISALRKDLARLEAEVEQLEERIAQL---- 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  664 velkstkqdgdkslsavpdigqchQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSA 743
Cdd:TIGR02168  753 ------------------------SKELTELEAEIEELEERLEEAEE----ELAEAEAEIEELEAQIEQLKEELKALREA 804

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  744 FTALSEErdqlLSQVKELsmVTELRAQVKQLEMNLAEAERQ-RRLDYESQTahdnlLTEQIHSLSIEAKSKDVKIEVLQN 822
Cdd:TIGR02168  805 LDELRAE----LTLLNEE--AANLRERLESLERRIAATERRlEDLEEQIEE-----LSEDIESLAAEIEELEELIEELES 873

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  823 ELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKR----DVETLQ 898
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLTL 953

                          890       900       910
                   ....*....|....*....|....*....|..
gi 1483569506  899 QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLG 930
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIKELG 985
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1500-2093 1.03e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 1.03e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1500 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD---RSLLENQSLSSSCES 1576
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1577 LKLALEGLTEDKEKL---VKEIESLKSSKIAESTEWQEKHKELQ------KEYEILLQSYENVSNEAERIQHVVEAVRQE 1647
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1648 KQELYGKLRstEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPagdtakecmetllssna 1727
Cdd:PRK03918   323 INGIEERIK--ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG----------------- 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1728 smkEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvSKQANLEATEKHDNQTNV-----TEEGTQSIPGET 1802
Cdd:PRK03918   384 ---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK---ELKKAIEELKKAKGKCPVcgrelTEEHRKELLEEY 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1803 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKEriagLEEE-KQKNKEFSQTLENEKNTLLSQ 1881
Cdd:PRK03918   458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE----LEEKlKKYNLEELEKKAEEYEKLKEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1882 ISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLES 1961
Cdd:PRK03918   534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYN 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1962 EMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKI 2040
Cdd:PRK03918   603 EYLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSREL 675

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1483569506 2041 SALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2093
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 688-1261 1.73e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.73e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  688 QDELERLKSQILELElnfhKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKelsmvtEL 767
Cdd:COG1196    238 EAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------RL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  768 RAQVKQLEMNLAEAERQRrldyESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN 847
Cdd:COG1196    308 EERRRELEERLEELEEEL----AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  848 KESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKF 927
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  928 SLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEelqhefdllkKENEQRKRKLQAALInr 1007
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA----------ALLLAGLRGLAGAVA-- 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1008 kELLQRVSRLEEELANLKDESKKEIPLSETERGE--VEEDKENKEysekcvtskcqeieiyLKQTISEKEVELQHIRKDL 1085
Cdd:COG1196    528 -VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAaaIEYLKAAKA----------------GRATFLPLDKIRARAALAA 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1086 EEKLAAEEQFQALVKQMNQTLQDK-TNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWK 1164
Cdd:COG1196    591 ALARGAIGAAVDLVASDLREADARyYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1165 PELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQ 1244
Cdd:COG1196    671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750

                          570
                   ....*....|....*..
gi 1483569506 1245 VRESIDGKLPSTDQQES 1261
Cdd:COG1196    751 EALEELPEPPDLEELER 767
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1847-2629 3.17e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.63  E-value: 3.17e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1847 IDQLKERIAGLEEEKQKNKEFSQTLE-----------NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTK 1915
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKekreyegyellKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1916 LKETAEEEKDDLEERLMNQLaelngsignycqdvtdaQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEy 1995
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1996 lekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHR 2075
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD-------KEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2076 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsQMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRR 2155
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWK----LEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2156 EKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRV---IDEAKKWERKFSDAIQS------ 2226
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVaagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2227 -----------KEEEIRLKEDNCS--------VLKDQLRQMSIHMEE--LKINISRLEHDKQ-------------IWESK 2272
Cdd:TIGR02169  550 nnvvveddavaKEAIELLKRRKAGratflplnKMRDERRDLSILSEDgvIGFAVDLVEFDPKyepafkyvfgdtlVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2273 AQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2352
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2353 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQqhdkEIKELENLLSQEEEenivl 2432
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL--------SSLEQEIENVKS----ELKELEARIEELEE----- 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2433 eeenkkavdKTNQLMETLKTIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL---IQEAAAE 2509
Cdd:TIGR02169  773 ---------DLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQELQEQ 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2510 NNKLKEEIRGLRSHMDDLNSENAKLDAELiqyredlnqvitikdsqqkqllevqlqqnKELENKYAKLEEKLKESEEANE 2589
Cdd:TIGR02169  842 RIDLKEQIKSIEKEIENLNGKKEELEEEL-----------------------------EELEAALRDLESRLGDLKKERD 892

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1483569506 2590 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE 2629
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 640-1235 4.93e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 4.93e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  640 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 719
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  720 AKEISNLNQLIEEFKKNADNNssaftaLSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLL 799
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDK------IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  800 TEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL-------EGAERVRHISSKVEELSQA 872
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  873 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 952
Cdd:pfam15921  477 LRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  953 QVEEDNEVSSGLKQNYDEMSP----------AGQISKEELQ----------HEFDLLKKENEQRKRKLQAAL----INRK 1008
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEkeindrrlelQEFKILKDKKDAKIRELEARVsdleLEKV 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1009 ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY---LKQTISEKEVELQHIRKDL 1085
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTL 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1086 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEisenqaiIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1165
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK-------IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1166 ELEEKILALEkekeqlQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1235
Cdd:pfam15921  789 AGELEVLRSQ------ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPG 852
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 761-1492 7.68e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 7.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  761 LSMVTELRAQVKQLEMNLAEAER-----QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVlQNELDDVQLQFSEQS 835
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEeleklTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRV-KEKIGELEAEIASLE 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  836 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEisfsM 915
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE----T 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  916 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQnydemspagqiSKEELQHEFDLLKKENEQ 995
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-----------KINELEEEKEDKALEIKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  996 RKRKLQAALINRKELLQRVSRLEEELANLKDE---SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTIS 1072
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEYDRVEKElskLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGS 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1073 EKE-----VE------LQHIRKDLEEKLAAEEQFQALVK----------QMNQTLQDKT---------NQIDLL----QA 1118
Cdd:TIGR02169  533 VGEryataIEvaagnrLNNVVVEDDAVAKEAIELLKRRKagratflplnKMRDERRDLSilsedgvigFAVDLVefdpKY 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1119 EISENQAIIQKLITSNTDASD--GDSVALVK---ETVVISPPCTGSS------EHWKPELEEKILALEKEKEQLQKKLQE 1187
Cdd:TIGR02169  613 EPAFKYVFGDTLVVEDIEAARrlMGKYRMVTlegELFEKSGAMTGGSraprggILFSRSEPAELQRLRERLEGLKRELSS 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1188 ALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKlpsTDQQESCSSTPG 1267
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK---SELKELEARIEE 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1268 LEEPLFKATEQhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQL 1347
Cdd:TIGR02169  770 LEEDLHKLEEA------------------LNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1348 QEqinkqglEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAA 1426
Cdd:TIGR02169  832 EK-------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1483569506 1427 LTKIQTEIIEQEDLIKALHTQLEMQAkehdERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQA 1492
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALE----EELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1844-2344 8.43e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 65.09  E-value: 8.43e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1844 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLKETAEEE 1923
Cdd:PRK03918   230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDE 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1924 KDDLEERLMNQLAELNGsIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE------EEKQQLVKEKTKVESEIRKEYLE 1997
Cdd:PRK03918   309 LREIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTPE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1998 KIQGAQKEPGNKShaKELQELLKEKQQEVKQLQKDCIRYQEKISALER------------TVKALEFVQTESQKDLEITK 2065
Cdd:PRK03918   388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2066 ENLAQAVEHRKKAQAELASFKVLLddtqsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2145
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2146 MQ------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL----QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2215
Cdd:PRK03918   541 IKslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2216 werkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHdkqiweskaqtevqlqqkvcdtlqgenkell 2295
Cdd:PRK03918   621 --------LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY------------------------------- 661

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*....
gi 1483569506 2296 sqlEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2344
Cdd:PRK03918   662 ---EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 48-613 9.39e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 9.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   48 EDVQERLAyaeqlvvELKDIIRQKDVQLqqkdEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQ 127
Cdd:COG1196    182 EATEENLE-------RLEDILGELERQL----EPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  128 SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  208 QTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 287
Cdd:COG1196    331 ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  288 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKL--SFHNLQEEMHHLLEQFEQAGQAQAELE 365
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALleLLAELLEEAALLEAALAELLEELAEAA 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  366 SRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQA---------VQSAQTIQQLEDQLQQKS 436
Cdd:COG1196    491 ARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAlaaalqnivVEDDEVAAAAIEYLKAAK 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  437 KEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELK--AENEKLSSQIT 514
Cdd:COG1196    571 AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRraVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  515 LLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEAD 594
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570
                   ....*....|....*....
gi 1483569506  595 HEVLDQKEMKQMEGEGIAP 613
Cdd:COG1196    731 EAEREELLEELLEEEELLE 749
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2225-2776 1.35e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 1.35e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2225 QSKEEEIRLKEDNCSVLKDQLRQMSIhmEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2304
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2305 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2384
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2385 KEQKIISLLSGKEEA-------------IQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLK 2451
Cdd:COG1196    370 AEAELAEAEEELEELaeellealraaaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2452 TIKK---ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSII-LEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2527
Cdd:COG1196    450 EEAEleeEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2528 NSENAKLDAELIQYREDLNQVITIKDSQQ-KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2606
Cdd:COG1196    530 IGVEAAYEAALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2607 KEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLK 2686
Cdd:COG1196    610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2687 KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKY 2766
Cdd:COG1196    690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769

                          570
                   ....*....|
gi 1483569506 2767 DASLKELAQL 2776
Cdd:COG1196    770 ERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2056-2667 1.78e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.78e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2056 ESQKDLEITKENLAQA----VEHRK-----KAQAELAsfkvllddtqsEAARVLADNLKLKK-ELQSNKESVKSQMKQKD 2125
Cdd:COG1196    176 EAERKLEATEENLERLedilGELERqleplERQAEKA-----------ERYRELKEELKELEaELLLLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2126 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAftksmssLQDD 2205
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE-------LEER 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2206 RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2285
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2286 TLQgENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE 2365
Cdd:COG1196    398 LAA-QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2366 TDLQASRELTSRLHEEINMKEQkIISLLSGKEEAIQvAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQ 2445
Cdd:COG1196    477 AALAELLEELAEAAARLLLLLE-AEADYEGFLEGVK-AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2446 LMETLKTIKKENIQQKAQLDSF-----VKSMSSLQNDRDRIVGDYQQLEERHLSIILE-KDQLIQEAAAENNKLKEEIRG 2519
Cdd:COG1196    555 DDEVAAAAIEYLKAAKAGRATFlpldkIRARAALAAALARGAIGAAVDLVASDLREADaRYYVLGDTLLGRTLVAARLEA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2520 LRSHMDDLNSENAKLDAELIQyREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQ 2599
Cdd:COG1196    635 ALRRAVTLAGRLREVTLEGEG-GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1483569506 2600 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRlsalfSSSQKRIAELEEEL 2667
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-----EELERELERLEREI 776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1838-2622 2.15e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 2.15e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1838 DEINNYLQQIDQLKERIAGLEEEKQKN-KEFSQTLENEKNTLLSQISTKDGELKMLQEEVTK-----------MNLLNQQ 1905
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAKleaeidkllaeIEELERE 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1906 IQEELSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKT 1985
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELED-LRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1986 KVESEIrkeylEKIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEItK 2065
Cdd:TIGR02169  424 DLNAAI-----AGIEAKINE--LEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE-A 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2066 ENLAQAVEHRkkaQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ----KDEDL---------ERRL 2132
Cdd:TIGR02169  496 EAQARASEER---VRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvvEDDAVakeaiellkRRKA 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2133 EQAEEKHLKEKKNMQEKLDALRREKVHleetigEIQVTLNKKDKEVQQ----------LQENLDSTVTQLAAFtkSMSSL 2202
Cdd:TIGR02169  573 GRATFLPLNKMRDERRDLSILSEDGVI------GFAVDLVEFDPKYEPafkyvfgdtlVVEDIEAARRLMGKY--RMVTL 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2203 QDD----RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDncsvLKDQLRQMSIHMEELKiNISRLEHDKQIWESKAQTEVQ 2278
Cdd:TIGR02169  645 EGElfekSGAMTGGSRAPRGGILFSRSEPAELQRLRER----LEGLKRELSSLQSELR-RIENRLDELSQELSDASRKIG 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2279 LQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEadIQNSK 2358
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEIQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2359 FSYEQLETDLQASRELTSRLHEEINMKEQKiisllsgkeeaiqvaiaelRQQHDKEIKELENLLsqeeEENIVLEEENKK 2438
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLE-------------------KEYLEKEIQELQEQR----IDLKEQIKSIEK 854

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2439 AVDKTNQLMETLKTIKKENIQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAENNKLKEEIR 2518
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLE---SRLGDLKKERDELEAQLRELERK-----------IEELEAQIEKKRKRLS 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2519 GLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK-QLLEVQLQQNKELENKYAKLEeklkeseeanEDLRRSFNA 2597
Cdd:TIGR02169  921 ELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAElQRVEEEIRALEPVNMLAIQEY----------EEVLKRLDE 990

                          810       820
                   ....*....|....*....|....*
gi 1483569506 2598 LQEEKQDLSKEIESLKVSISQLTRQ 2622
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1632-2407 3.33e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 3.33e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1632 NEAERIQHVVEAVRQ-EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHP 1710
Cdd:TIGR02169  208 EKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1711 AGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDnqtnv 1790
Cdd:TIGR02169  288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL----- 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1791 tEEGTQSIPGETEEQDSLSMSTRptcsesvpsaksanpavskdfsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1870
Cdd:TIGR02169  363 -KEELEDLRAELEEVDKEFAETR------------------------DELKDYREKLEKLKREINELKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1871 LENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLmnqlaelngsignycqdvt 1950
Cdd:TIGR02169  418 LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY------------------- 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1951 daqiknELLESEMKNLKKCVSELEEEKQQLVKEKT--KVESEIRKEYLEKIQGAQKEPG--NKSHAKELQELLKEKQQEV 2026
Cdd:TIGR02169  479 ------DRVEKELSKLQRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGTVAQLGsvGERYATAIEVAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2027 ----KQLQKDCIRYQEKISALERTVKALEFVQTEsQKDLEITKEN-----LAQAVEHRKKAQaelASFKVLLDDT----Q 2093
Cdd:TIGR02169  553 vvedDAVAKEAIELLKRRKAGRATFLPLNKMRDE-RRDLSILSEDgvigfAVDLVEFDPKYE---PAFKYVFGDTlvveD 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2094 SEAARVLADNLKL--------------------KKELQSNKESVKSQMKQKDEDLErRLEQAEEKHLKEKKNMQEKLDAL 2153
Cdd:TIGR02169  629 IEAARRLMGKYRMvtlegelfeksgamtggsraPRGGILFSRSEPAELQRLRERLE-GLKRELSSLQSELRRIENRLDEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2154 RREKVHLEETIGEIQvtlnkkdKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQSKEEEIRL 2233
Cdd:TIGR02169  708 SQELSDASRKIGEIE-------KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR----IEELEEDLHK 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2234 KEDNCSVLKDQLRQMSI-----HMEELKINISRLE----HDKQIWESKAQTEVQLQQKVcDTLQGENKELLSQLEETRHL 2304
Cdd:TIGR02169  777 LEEALNDLEARLSHSRIpeiqaELSKLEEEVSRIEarlrEIEQKLNRLTLEKEYLEKEI-QELQEQRIDLKEQIKSIEKE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2305 YHSSQNELAKLESELKSLKDQLTDLSnslekckEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2384
Cdd:TIGR02169  856 IENLNGKKEELEEELEELEAALRDLE-------SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928

                          810       820
                   ....*....|....*....|...
gi 1483569506 2385 KEQKIISLLSGKEEAIQVAIAEL 2407
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPEEEL 951
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2175-2928 4.43e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 4.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2175 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERkfSDAIQSKEEEIRLKEdncsvLKDQLRQMSIHMEE 2254
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYE-----LLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2255 LKINISRLEhdkqiwESKAQTEVQLQQKVCDTlqGENKELLSQLEEtrHLYHSSQNELAKLESELKSLKDQLTDLSNSLE 2334
Cdd:TIGR02169  242 IERQLASLE------EELEKLTEEISELEKRL--EEIEQLLEELNK--KIKDLGEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2335 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSgKEEAIQVAIAELRQQHDKE 2414
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-ELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2415 IKELENL-----------------LSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQND 2477
Cdd:TIGR02169  391 REKLEKLkreinelkreldrlqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2478 RDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENA---KLDAELIQYRED---------- 2544
Cdd:TIGR02169  471 LYDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaag 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2545 --LNQVITIKDSQQKQLLEVqLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQ 2622
Cdd:TIGR02169  547 nrLNNVVVEDDAVAKEAIEL-LKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2623 VTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSqkRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNE 2702
Cdd:TIGR02169  626 VEDIEAARRLMGKYRMVTLEGELFEKSGAMTGGS--RAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2703 TETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKrkydaslKELAQLKEQglL 2782
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELE-------ARIEELEED--L 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2783 NRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRK 2862
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK 854

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2863 SEEG----KQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQE 2928
Cdd:TIGR02169  855 EIENlngkKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA 924
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 560-1250 4.49e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.77  E-value: 4.49e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  560 KHKELSVLLLEMKEAQEEIAFLKLQLqgkraEEADHEVLDQKEMKQMEGEGIAPIKMKVFledtgqdfplmpneesslpa 639
Cdd:TIGR02168  223 RELELALLVLRLEELREELEELQEEL-----KEAEEELEELTAELQELEEKLEELRLEVS-------------------- 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  640 vEKEQASTEHQSR---TSEEISlndagvELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYE--- 713
Cdd:TIGR02168  278 -ELEEEIEELQKElyaLANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEelk 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  714 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEmnlaeaERQRRLDYESQ 792
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLE------DRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  793 TAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQ- 871
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGf 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  872 -----ALSQKELEITKMDQLLLEK-------KRDVET-----LQQTIEEKDQQVTEISFSMTEK-----------MVQLN 923
Cdd:TIGR02168  505 segvkALLKNQSGLSGILGVLSELisvdegyEAAIEAalggrLQAVVVENLNAAKKAIAFLKQNelgrvtflpldSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  924 EEKFSLGVEIKTLKEQLNLLSRAEEAKK----------------EQVEEDNEVSSGLKQNY-------DEMSPAGQISKE 980
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvDDLDNALELAKKLRPGYrivtldgDLVRPGGVITGG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  981 ELQHEFDLLK-----KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKC 1055
Cdd:TIGR02168  665 SAKTNSSILErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1056 VTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAE---EQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLit 1132
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL-- 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1133 SNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI---LKKAQEKERHLREE 1209
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLeeaLALLRSELEELSEE 902

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1483569506 1210 LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESID 1250
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1837-2550 7.65e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 61.99  E-value: 7.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1837 HDEINNYLQQIDQL-KERIAGLEEEKQKNKEFSQTLENEKNTLLSQIS----TKDGELKMlQEEVTKMN----LLNQQIQ 1907
Cdd:TIGR01612 1050 HTSIYNIIDEIEKEiGKNIELLNKEILEEAEINITNFNEIKEKLKHYNfddfGKEENIKY-ADEINKIKddikNLDQKID 1128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1908 EELSRVTKLKETAEEEKDDLEERLmnqlaelngsigNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK------QQLV 1981
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKAQI------------NDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKniydeiKKLL 1196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1982 KEKTKVESEirKEYLEKIQGAqkepgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERTVKALEFVQTESQKD 2060
Cdd:TIGR01612 1197 NEIAEIEKD--KTSLEEVKGI-----NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAyIEDLDEIKEKSPEIENEMGIE 1269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2061 LEITKENLAQAVEHRKKAQAELASFK--VLLDDTQSEAARVLADNLK------LKKELQSNKesvkSQMKQKDEDLERRL 2132
Cdd:TIGR01612 1270 MDIKAEMETFNISHDDDKDHHIISKKhdENISDIREKSLKIIEDFSEesdindIKKELQKNL----LDAQKHNSDINLYL 1345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2133 EQ-AEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDstvtqLAAFTKSMSSLQDDRDrvID 2211
Cdd:TIGR01612 1346 NEiANIYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDIN-----LEECKSKIESTLDDKD--ID 1418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2212 EAKKWERKFSDAIQSKEEEI-----RLKEDNCSVLK-----DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEvqlQQ 2281
Cdd:TIGR01612 1419 ECIKKIKELKNHILSEESNIdtyfkNADENNENVLLlfkniEMADNKSQHILKIKKDNATNDHDFNINELKEHID---KS 1495

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2282 KVCDTLQGENKEllsQLEETRHLYHSSQNELAKL-----ESELKSLKDQLTDLSNSL-EKCKEQKGNL---EGIIRQQEA 2352
Cdd:TIGR01612 1496 KGCKDEADKNAK---AIEKNKELFEQYKKDVTELlnkysALAIKNKFAKTKKDSEIIiKEIKDAHKKFileAEKSEQKIK 1572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2353 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISllsgkeeaiqvaIAELRQQHDKEIKELENLLSQEEE----E 2428
Cdd:TIGR01612 1573 EIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLK------------ISDIKKKINDCLKETESIEKKISSfsidS 1640

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2429 NIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQqleerhLSIIlekDQLIQEAAA 2508
Cdd:TIGR01612 1641 QDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYE------IGII---EKIKEIAIA 1711

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1483569506 2509 ENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVIT 2550
Cdd:TIGR01612 1712 NKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNT 1753
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-531 7.96e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 7.96e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   47 QEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGgtvlptep 126
Cdd:COG1196    332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE-------- 403

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  127 QSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQpAQSSTEMEEFVMMKQQLQEKEEFISTLQAQL 206
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE-AELEEEEEALLELLAELLEEAALLEAALAEL 482

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  207 SQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQ-------------ADVETEMQQKL--------RVLQRK 265
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGavavligveaayeAALEAALAAALqnivveddEVAAAA 562

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  266 LEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEkmELEVAERKLSFHNLQE 345
Cdd:COG1196    563 IEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLG--RTLVAARLEAALRRAV 640

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  346 EMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTI 425
Cdd:COG1196    641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  426 QQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVynegtqavTEENIASLQKRVVELENEKGAL----LLSSIELEE 501
Cdd:COG1196    721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEELP--------EPPDLEELERELERLEREIEALgpvnLLAIEEYEE 792

                          490       500       510
                   ....*....|....*....|....*....|....*
gi 1483569506  502 LKAENEKLSSQI-TLLEA----QNRTGEADREVSE 531
Cdd:COG1196    793 LEERYDFLSEQReDLEEAretlEEAIEEIDRETRE 827
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2309-2778 9.43e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.19  E-value: 9.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2309 QNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE--EINMKE 2386
Cdd:TIGR04523  151 EKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISElkKQNNQL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2387 QKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDS 2466
Cdd:TIGR04523  231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2467 FVKSmsSLQNDRDRIVGDYQQLEERHLSIilekdqliqeaaaenNKLKEEIRGLRSHMDDLNSENAKLDAELiqyREDLN 2546
Cdd:TIGR04523  311 ELKS--ELKNQEKKLEEIQNQISQNNKII---------------SQLNEQISQLKKELTNSESENSEKQREL---EEKQN 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2547 QVITIKDSQQKQLlevqlQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2626
Cdd:TIGR04523  371 EIEKLKKENQSYK-----QEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2627 QEEGTlglyhaqlkVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETETA 2706
Cdd:TIGR04523  446 TNQDS---------VKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK-EKELKKLNEEKKELEEKVKDL 515

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1483569506 2707 EERVAELARDLVEMEQKLLMVTKENKGLTAQIQS--FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2778
Cdd:TIGR04523  516 TKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQE 589
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1847-2162 1.15e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.15e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1847 IDQLKERIAGLEEEKQKNKEFsQTLENEKNTL-----LSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1921
Cdd:COG1196    195 LGELERQLEPLERQAEKAERY-RELKEELKELeaellLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1922 EEKDDLEERLmnqlaelngsignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG 2001
Cdd:COG1196    274 LELEELELEL------------------EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2002 AQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITK---ENLAQAVEHRKKA 2078
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAaqlEELEEAEEALLER 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2079 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKV 2158
Cdd:COG1196    416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495


                   ....
gi 1483569506 2159 HLEE 2162
Cdd:COG1196    496 LLEA 499
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 688-1216 1.18e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  688 QDELERLKSQILELELNFHKAQE---IYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SM 763
Cdd:COG1196    266 EAELEELRLELEELELELEEAQAeeyELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELeEE 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  764 VTELRAQVKQLEMNLAEAERQRRLDYESQTAHDnlltEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 843
Cdd:COG1196    346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAE----EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  844 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM-TEKMVQL 922
Cdd:COG1196    422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLlLLLEAEA 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  923 NEEKFSLGVEIKTLKEQLNLLSRA------EEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISkeelqhefDLLKKENEQR 996
Cdd:COG1196    502 DYEGFLEGVKAALLLAGLRGLAGAvavligVEAAYEAALEAALAAALQNIVVEDDEVAAAAI--------EYLKAAKAGR 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  997 KRKLQAALINRKELLQRVSRLEEEL-------ANLKDESKKEIPLSETERGE--VEEDKENKEYSEKCVTSKCQEIEIYL 1067
Cdd:COG1196    574 ATFLPLDKIRARAALAAALARGAIGaavdlvaSDLREADARYYVLGDTLLGRtlVAARLEAALRRAVTLAGRLREVTLEG 653

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1068 KQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVK 1147
Cdd:COG1196    654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506 1148 ETVVISPPCTGSSEHwkPELEEKILALEKEKEQLQKKLQEALTSRK--------AILKKAQEKERHlrEELKQQKDD 1216
Cdd:COG1196    734 REELLEELLEEEELL--EEEALEELPEPPDLEELERELERLEREIEalgpvnllAIEEYEELEERY--DFLSEQRED 806
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 871-1768 1.60e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 60.76  E-value: 1.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  871 QALSQKELEITKMDQLL---LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKfslgVEIKTLKEQLNLLSRAE 947
Cdd:pfam02463  146 IIAMMKPERRLEIEEEAagsRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKE----QAKKALEYYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  948 EAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 1027
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1028 SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTIS--EKEVELQHIRKDLEEKLAAEEQFQALVKQMNQT 1105
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKEleIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1106 LQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDsvalvketvvisppctgssEHWKPELEEKILALEKEKEQLQKKL 1185
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL-------------------EDLLKEEKKEELEILEEEEESIELK 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1186 QEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSST 1265
Cdd:pfam02463  443 QGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGG 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1266 PGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVF 1345
Cdd:pfam02463  523 RIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1346 QLQEQINKQGLEIESLKTVSHEAEVHAESLQQK--LESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVS--YLSGQLS 1421
Cdd:pfam02463  603 LNLAQLDKATLEADEDDKRAKVVEGILKDTELTklKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKelLEIQELQ 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1422 EKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL 1501
Cdd:pfam02463  683 EKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1502 KENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTvlgrLALLQEERDKLITEMDRSLLENQSLSSSCESLKLAL 1581
Cdd:pfam02463  763 EEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE----LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEEL 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1582 EGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERiqhvvEAVRQEKQELYGKLRSTEAN 1661
Cdd:pfam02463  839 ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE-----KEKEEKKELEEESQKLNLLE 913

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1662 KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHpaGDTAKECMETLLSSNASMKEELERVKMEYE 1741
Cdd:pfam02463  914 EKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER--NKRLLLAKEELGKVNLMAIEEFEEKEERYN 991

                          890       900
                   ....*....|....*....|....*..
gi 1483569506 1742 TLSKKFQSLMSEKDSLSEEVQDLKHQI 1768
Cdd:pfam02463  992 KDELEKERLEEEKKKLIRAIIEETCQR 1018
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1166-1657 1.99e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1166 ELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKerhlREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQV 1245
Cdd:PRK02224   217 ELDEEIERYEEQREQARETRDEA----DEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1246 ---RESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpDWPSHSEDASALQGgtSVAQIKAQLKEIEAE 1322
Cdd:PRK02224   289 eelEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRV--AAQAHNEEAESLRE--DADDLEERAEELREE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1323 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDE 1401
Cdd:PRK02224   365 AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTARERVEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1402 LQKL---------------------ISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKA------LHTQLEMQAK- 1453
Cdd:PRK02224   445 AEALleagkcpecgqpvegsphvetIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAedrierLEERREDLEEl 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1454 --EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVES- 1530
Cdd:PRK02224   525 iaERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADa 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1531 ---------QVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLEN-----QSLSSSCESLKLALEGLTEDKEKLVKEIE 1596
Cdd:PRK02224   605 edeierlreKREALAELNDERRERLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERDDLQAEIG 684

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1483569506 1597 SLKSSkIAESTEWQEKHKELQKEYEILLQSYENVSneaeriqhvveavrqEKQELYGKLRS 1657
Cdd:PRK02224   685 AVENE-LEELEELRERREALENRVEALEALYDEAE---------------ELESMYGDLRA 729
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1834-2051 2.16e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.39  E-value: 2.16e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1834 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEvtkMNLLNQQIQEELSRV 1913
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE---LAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1914 TKLKETAEEEKDDLEERL-----MNQLAELNGSIGNycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1988
Cdd:COG4942     93 AELRAELEAQKEELAELLralyrLGRQPPLALLLSP--EDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1483569506 1989 SEiRKEYLEKIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALE 2051
Cdd:COG4942    171 AE-RAELEALLAELEEE------RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2218-2778 2.17e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 2.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2218 RKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQiwesKAQTEVQLQQKvcdTLQGENKELLSQ 2297
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE----EAQAEEYELLA---ELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2298 LEETRHLyhssQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSR 2377
Cdd:COG1196    308 EERRREL----EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2378 LHEEINMKEQKIISLLSGKEEAIQV--AIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKK 2455
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAeeALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2456 ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsiiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLD 2535
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLE------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2536 AELIQYREDLNQVITIKDSQQ-KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKV 2614
Cdd:COG1196    538 AALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2615 SISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHH 2694
Cdd:COG1196    618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2695 DAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFG---------------------RSMSSLQNSRD 2753
Cdd:COG1196    698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEelleeealeelpeppdleeleRELERLEREIE 777

                          570       580       590
                   ....*....|....*....|....*....|..
gi 1483569506 2754 H-------ANEELDELKRKYDASLKELAQLKE 2778
Cdd:COG1196    778 AlgpvnllAIEEYEELEERYDFLSEQREDLEE 809
PTZ00121 PTZ00121
MAEBL; Provisional
 1588-2387 2.19e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 2.19e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1588 KEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQE---LYGKLRSTEANKKE 1664
Cdd:PTZ00121  1153 RVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEearKAEDAKKAEAVKKA 1232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1665 TEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERV-------- 1736
Cdd:PTZ00121  1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKAdeakkkae 1312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1737 -KMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQanleatEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPT 1815
Cdd:PTZ00121  1313 eAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA------EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK 1386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1816 cSESVPSAKSANPAVSKDFSSHDEINNYL---QQIDQLK---ERIAGLEEEKQKNKEFSQTLENEKNtllSQISTKDGEL 1889
Cdd:PTZ00121  1387 -AEEKKKADEAKKKAEEDKKKADELKKAAaakKKADEAKkkaEEKKKADEAKKKAEEAKKADEAKKK---AEEAKKAEEA 1462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1890 KMLQEEVTKMNLLNQQiQEELSRVTKLKETAEEEKDDLEErlmnqlAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKC 1969
Cdd:PTZ00121  1463 KKKAEEAKKADEAKKK-AEEAKKADEAKKKAEEAKKKADE------AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK 1535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1970 VSELEEEKQQLVKEKTKVESEIRK-EYLEKIQGAQKEpgnkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2048
Cdd:PTZ00121  1536 ADEAKKAEEKKKADELKKAEELKKaEEKKKAEEAKKA-------EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK 1608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2049 ALEFVQTESQKdleITKENLAQAVEHRKKaqAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK---ESVKSQMKQKD 2125
Cdd:PTZ00121  1609 AEEAKKAEEAK---IKAEELKKAEEEKKK--VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKaeeDKKKAEEAKKA 1683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2126 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD---KEVQQLQENLDSTVTQLAAFTKSMSSL 2202
Cdd:PTZ00121  1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEeakKEAEEDKKKAEEAKKDEEEKKKIAHLK 1763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2203 QDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNcsVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQK 2282
Cdd:PTZ00121  1764 KEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK--KIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM 1841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2283 VCDtlqgENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYE 2362
Cdd:PTZ00121  1842 QLE----EADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDD 1917

                          810       820
                   ....*....|....*....|....*
gi 1483569506 2363 QLETDLQASRELTSRLHEEINMKEQ 2387
Cdd:PTZ00121  1918 KLDKDEYIKRDAEETREEIIKISKK 1942
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1420-1939 4.09e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.28  E-value: 4.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1420 LSEKEAALTKIQTEI--IEQEDLIKALHTqLEMQAKEHDERIKQLQVE---LCEMKQKPEEIGEESRAKQQIQRKLQAAL 1494
Cdd:PRK02224   182 LSDQRGSLDQLKAQIeeKEEKDLHERLNG-LESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELETLEAEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1495 ----ISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSL 1570
Cdd:PRK02224   261 edlrETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1571 SSSCESLK---LALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1647
Cdd:PRK02224   341 NEEAESLRedaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1648 KQELYGKLRSTEANKKETEKQLQEAEQEMEE----------MKEKMRKFAKSKQQKILELEEENDRLRAEVhpagdtake 1717
Cdd:PRK02224   421 RDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEV--------- 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1718 cmetllssnASMKEELERVKMEYETlSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANL-EATEKHDNQTNVTEEGTQ 1796
Cdd:PRK02224   492 ---------EEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRETIEEKRERAEELrERAAELEAEAEEKREAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1797 SIPGETEEqdslSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN 1876
Cdd:PRK02224   562 EAEEEAEE----AREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKR 637

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1483569506 1877 TLLSQIStkDGELKMLQEEvtkmnllNQQIQEELSRVTKLKETAEEEKDDLEER---LMNQLAELN 1939
Cdd:PRK02224   638 ELEAEFD--EARIEEARED-------KERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELE 694
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 48-960 4.39e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 4.39e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQkdeaLQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVlptepq 127
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLER----LRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAI------ 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  128 sEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEfvmmkqqlqekeefistLQAQLS 207
Cdd:TIGR02169  243 -ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGE-----------------LEAEIA 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  208 QTQAEQAAQLSSMQQVVREkdaRFETQVRLHEdellqlvtqadvetemqqklrvLQRKLEEHEESLVGRAQVVDLLQQEL 287
Cdd:TIGR02169  305 SLERSIAEKERELEDAEER---LAKLEAEIDK----------------------LLAEIEELEREIEEERKRRDKLTEEY 359

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  288 TAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMElevaerklsfhNLQEEMHHLLEQFEQAGQAQAELESR 367
Cdd:TIGR02169  360 AELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREIN-----------ELKRELDRLQEELQRLSEELADLNAA 428

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  368 YSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEqavqsaqtIQQLEDQLQQKSKEISQFLNRLP 447
Cdd:TIGR02169  429 IAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE--------YDRVEKELSKLQRELAEAEAQAR 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  448 LQQHETASQTSFPDVYNEGTQAV---TEENIASLQKRVVELENEKGAlllssiELEELKAENEKLSSQITLLEAQNRTGE 524
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVAAGN------RLNNVVVEDDAVAKEAIELLKRRKAGR 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  525 AdrevSEISIVDIANKRSSSAEESGQDVLentfsqkhkELSVLLLEMKEAQEEIAFLKLQLQG-KRAEEADHEVLDQKEM 603
Cdd:TIGR02169  575 A----TFLPLNKMRDERRDLSILSEDGVI---------GFAVDLVEFDPKYEPAFKYVFGDTLvVEDIEAARRLMGKYRM 641

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  604 KQMEGEGIAP---IKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAV 680
Cdd:TIGR02169  642 VTLEGELFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEI 721

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  681 PDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKE 760
Cdd:TIGR02169  722 EKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS 801

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  761 lsmvtELRAQVKQLEMNLAEAERQ-RRLDYESQTAHDnllteqihslsiEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 839
Cdd:TIGR02169  802 -----KLEEEVSRIEARLREIEQKlNRLTLEKEYLEK------------EIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  840 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEkM 919
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE-D 943

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|.
gi 1483569506  920 VQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEV 960
Cdd:TIGR02169  944 EEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEV 984
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1306-2184 4.55e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 4.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1306 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1385
Cdd:pfam02463  161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1386 IagLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1465
Cdd:pfam02463  241 L--LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1466 LCEMKQKpeeigeesrakqqIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1545
Cdd:pfam02463  319 SEKEKKK-------------AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1546 LALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1625
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1626 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1705
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1706 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1785
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1786 NQTNVTEEGTQSIPGETEEQDSLSMstrptcsesVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1865
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRK---------GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1866 EFSQTLENEKNTLLSQISTKDGELKMLQEEVT-KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1944
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQeAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1945 YCQDVTDAQIKNElLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepgnKSHAKELQELLKEKQQ 2024
Cdd:pfam02463  777 AEEREKTEKLKVE-EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK--------EEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2025 EVKQLQKDCIRYQEKISALERTVKALEfvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL 2104
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLL----KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2105 KLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2184
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1166-1707 4.61e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 4.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1166 ELEEKILALEKEKEQLQK--KLQEALTSRKAILKKAqeKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQI 1243
Cdd:COG1196    197 ELERQLEPLERQAEKAERyrELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1244 QVRESIDgklpstdqqescsstpgleeplfkateqhhtqpvlesnlcpdwpshsedasalqggtSVAQIKAQLKEIEAEK 1323
Cdd:COG1196    275 ELEELEL---------------------------------------------------------ELEEAQAEEYELLAEL 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1324 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHlrelqpKLDELQ 1403
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE------ALLEAE 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1404 KLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAK 1483
Cdd:COG1196    372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1484 QQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRS 1563
Cdd:COG1196    452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1564 LLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS-----------SKIAESTEWQEKHKELQKEYEILLQSYENVSN 1632
Cdd:COG1196    532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 1633 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1707
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1064-1929 6.88e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 6.88e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1064 EIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDAsDGDSV 1143
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL-QKELY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1144 ALVKEtvvisppctgssehwKPELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQ 1223
Cdd:TIGR02168  292 ALANE---------------ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELAEELAELEEKLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1224 FDEQSKENENIGDQLRQLQIQVREsidgklpstDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpSHSEDasal 1303
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEE---------LEEQLETLRSKVAQLELQIASLNNEIERLEARL-----ERLED---- 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1304 qggtSVAQIKAQLKEIEAEKVELELKVSSTtsELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQ 1383
Cdd:TIGR02168  415 ----RRERLQQEIEELLKKLEEAELKELQA--ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1384 LQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEK-------EAALtkiqtEIIEQEDLIKALHTQLE--MQAKE 1454
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAI-----EAALGGRLQAVVVENLNaaKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1455 HDERIKQLQVELCEMKQKPEeigeesrakQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1534
Cdd:TIGR02168  564 FLKQNELGRVTFLPLDSIKG---------TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1535 QNKEK-------------DTVLGRLALLQ--EERDKLITEMDRSLLENQS----LSSSCESLKLALEGLTEDKEKLVKEI 1595
Cdd:TIGR02168  635 LELAKklrpgyrivtldgDLVRPGGVITGgsAKTNSSILERRREIEELEEkieeLEEKIAELEKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1596 ESLKSSKIAESTewqeKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEkqlqeaeQE 1675
Cdd:TIGR02168  715 EQLRKELEELSR----QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE-------AE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1676 MEEMKEKMRKFAKSKQQKILELEEENDRLRAevhpagdtakecmetLLSSNASMKEELERVKMEYETLSKKFQSLMSEKD 1755
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTL---------------LNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1756 SLSEEVQDLKHQIEGNVSKQANLE-ATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKdf 1834
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELEsELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ-- 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1835 sSHDEINNYLQQIDQLKERIAgleEEKQKNKEFSQTLENEKNTLLSQIstkDGELKMLQEEVTKMNLLNQQIQEELSRVT 1914
Cdd:TIGR02168  927 -LELRLEGLEVRIDNLQERLS---EEYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKELGPVNLAAIEEYEELK 999

                          890
                   ....*....|....*
gi 1483569506 1915 KLKETAEEEKDDLEE 1929
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTE 1014
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1438-2183 8.74e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 8.74e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1438 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1514
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKfylRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1515 RGT-IERLTKSLADVESQVSAqnkekdtVLGRLALLQEERDKLITEMDR-SLLENQSLSSSCESLKLALEgltedkeklv 1592
Cdd:pfam15921  168 SNTqIEQLRKMMLSHEGVLQE-------IRSILVDFEEASGKKIYEHDSmSTMHFRSLGSAISKILRELD---------- 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1593 KEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYEnvsneaERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1672
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEII 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1673 EQEMEEMKEKMrkfakskQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLms 1752
Cdd:pfam15921  305 QEQARNQNSMY-------MRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNL-- 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1753 eKDSLSEEVQDL-KHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVS 1831
Cdd:pfam15921  376 -DDQLQKLLADLhKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1832 KDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM----NLLNQQIQ 1907
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLrsrvDLKLQELQ 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1908 EELSRVTKLKETAEE---------EKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQ 1978
Cdd:pfam15921  535 HLKNEGDHLRNVQTEcealklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKD 614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1979 QLVKEKTKVESEIRKEYLEKIQ----GAQKEPGNKSHAKELQELLKE---KQQEVKQLQKDC----IRYQEKISALERTV 2047
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKlvnaGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTT 694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2048 KALEFVQTESQKDLEITKENL-------AQAVEHRKKAQAELASFKVLLDDTQSEaarvladnLKLKKELQSNKESVKSQ 2120
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLksmegsdGHAMKVAMGMQKQITAKRGQIDALQSK--------IQFLEEAMTNANKEKHF 766

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1483569506 2121 MKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQE 2183
Cdd:pfam15921  767 LKEEKNKLSQELSTVA----TEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2643-2946 9.29e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 9.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2643 EEEVHRLSALFSSSQKRIAELEEelvcvQKEAAKKVGEIEDKLKK--------ELKHLHHDAGIMRNETETAEERVAELA 2714
Cdd:COG1196    185 EENLERLEDILGELERQLEPLER-----QAEKAERYRELKEELKEleaellllKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2715 RDLVEME-------QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2787
Cdd:COG1196    260 AELAELEaeleelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2788 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR----KS 2863
Cdd:COG1196    340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerleRL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2864 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEEL 2943
Cdd:COG1196    420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499


                   ...
gi 1483569506 2944 RQE 2946
Cdd:COG1196    500 EAD 502
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 551-1441 1.56e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 1.56e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  551 DVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQkemkqmegegiapikmkvfledtgqdfplm 630
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS------------------------------ 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  631 pneesslpavEKEQASTEHQSR---TSEEISlndagvELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHK 707
Cdd:TIGR02168  278 ----------ELEEEIEELQKElyaLANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  708 AQEIYE---KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEmnlaeaER 783
Cdd:TIGR02168  342 LEEKLEelkEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLE------DR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  784 QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHIS 863
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  864 SKVEELSQalsqkeleITKMDQLLLEKKRDVETLQQTIEEKdqqvteISFsmtekmvqlnEEKFSLGVEIkTLKEQLN-L 942
Cdd:TIGR02168  496 RLQENLEG--------FSEGVKALLKNQSGLSGILGVLSEL------ISV----------DEGYEAAIEA-ALGGRLQaV 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  943 LSRAEEAKKEQVEEDNEVSSG------LKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 1016
Cdd:TIGR02168  551 VVENLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1017 LEEELANLKDESKKEIPLSE-----TERGEVEEDKENKEYSekcVTSKCQEIEIyLKQTISEKEVELQHIRKDLEEKLAA 1091
Cdd:TIGR02168  631 LDNALELAKKLRPGYRIVTLdgdlvRPGGVITGGSAKTNSS---ILERRREIEE-LEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1092 EEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVisppctgssEHWKPELEEKI 1171
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL---------EERLEEAEEEL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1172 LALEKEKEQLQ---KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1248
Cdd:TIGR02168  778 AEAEAEIEELEaqiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES- 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1249 idgklpSTDQQEScsstpgLEEPLFKATEQHHtqpvlesnlcpdwpSHSEDASALQggTSVAQIKAQLKEIEAEKVELEL 1328
Cdd:TIGR02168  857 ------LAAEIEE------LEELIEELESELE--------------ALLNERASLE--EALALLRSELEELSEELRELES 908

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1329 KVSSTTSELTKKSEEVFQLQEQINKQGLEIESLK-TVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKL- 1405
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQeRLSEEYSLTLEEAEALENKIEDDEEEARrRLKRLENKIKELGPVn 988

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|..
gi 1483569506 1406 ------ISKKEEDVSYLSGQLSEKEAALTKIQtEIIEQEDLI 1441
Cdd:TIGR02168  989 laaieeYEELKERYDFLTAQKEDLTEAKETLE-EAIEEIDRE 1029
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1392-1608 1.68e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 1.68e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1392 LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1471
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1472 KPEEIGEESRAKQQIQRKLQAALI----SRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLA 1547
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1483569506 1548 LLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE 1608
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1320-1983 1.74e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 57.34  E-value: 1.74e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1320 EAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL-EHLRELQPK 1398
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1399 LDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEhderIKQLQVELCEMKQKPEEIGE 1478
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQ----KEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1479 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLIT 1558
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1559 EMDRSLLEnqslsssCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTewQEKHKELQKEYEILLQSYENVSNEAERIQ 1638
Cdd:TIGR04523  268 QLSEKQKE-------LEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWN--KELKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1639 HVVEAVRQEKQELYGKLRSTEANKKETEKqlqeaeqemeemkekmrkfaksKQQKILELEEENDRLraevhpagdtaKEC 1718
Cdd:TIGR04523  339 QLNEQISQLKKELTNSESENSEKQRELEE----------------------KQNEIEKLKKENQSY-----------KQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1719 METLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLeatEKHDNQTNVTEEGTQSI 1798
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL---TNQDSVKELIIKNLDNT 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1799 PGETEEQDSlsmstrpTCSESVPSAKSANPAVSKDFSSH-DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNT 1877
Cdd:TIGR04523  463 RESLETQLK-------VLSRSINKIKQNLEQKQKELKSKeKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKE 535

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1878 LLSQISTKDGELKMLQEEVTKMNL------LNQQIQEELSRVTKLKETAEEEKDDLEER------LMNQLAELNGSIGNY 1945
Cdd:TIGR04523  536 KESKISDLEDELNKDDFELKKENLekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKekekkdLIKEIEEKEKKISSL 615

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 1483569506 1946 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKE 1983
Cdd:TIGR04523  616 EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653
PTZ00121 PTZ00121
MAEBL; Provisional
 1310-1866 2.12e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 2.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1310 AQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTvsHEAEVHAESLQQKLESSQLQIAGL 1389
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK--EEAKKKADAAKKKAEEKKKADEAK 1397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1390 EHLRELQPKLDELQKLIS--KKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelc 1467
Cdd:PTZ00121  1398 KKAEEDKKKADELKKAAAakKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD---- 1473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1468 EMKQKPEEI--GEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1545
Cdd:PTZ00121  1474 EAKKKAEEAkkADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1546 LALLQEERDKLITEMDRSLLENQSLSS-SCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILL 1624
Cdd:PTZ00121  1554 AEELKKAEEKKKAEEAKKAEEDKNMALrKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK 1633

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1625 QSYENVSNEAERIQHvVEAVRQEKQELYGKlRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1704
Cdd:PTZ00121  1634 KVEQLKKKEAEEKKK-AEELKKAEEENKIK-AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1705 RAEVHPAGDTAKECMETLL-SSNASMKEELERVKMEY----ETLSKKFQSLMSEKDSLSEEVQDLKHQI------EGNVS 1773
Cdd:PTZ00121  1712 AEEKKKAEELKKAEEENKIkAEEAKKEAEEDKKKAEEakkdEEEKKKIAHLKKEEEKKAEEIRKEKEAVieeeldEEDEK 1791

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1774 KQANLEATEK--HDNQTNVTEEGTQSIP----------GETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEIN 1841
Cdd:PTZ00121  1792 RRMEVDKKIKdiFDNFANIIEGGKEGNLvindskemedSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFN 1871

                          570       580
                   ....*....|....*....|....*
gi 1483569506 1842 NYLQQIDQLKERIAGLEEEKQKNKE 1866
Cdd:PTZ00121  1872 KEKDLKEDDEEEIEEADEIEKIDKD 1896
PTZ00121 PTZ00121
MAEBL; Provisional
 707-1234 2.82e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.82e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  707 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQ 784
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  785 RRLDYESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 857
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  858 RVRHISSKVEELSQA--LSQKELEITKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 933
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  934 KTLKEqlnlLSRAEEAKKEQVEEDNEVssglKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1013
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1014 VSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE 1093
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1094 QFQAlvKQMNQTLQDKTNQIDLLQAEISENQaiiqklitsntdasdgdsvalvketvvisppctgssehwKPELEEKILA 1173
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1483569506 1174 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1234
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1585-2162 4.01e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 56.23  E-value: 4.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1585 TEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIqhvvEAVRQEKQELYGKLRSTEANKKE 1664
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI----EELEKELESLEGSKRKLEEKIRE 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1665 TEKQLQEAEQEMEEMKEKM----------------RKFAKSKQQKILELEEENDRLRAEVhpagdtakECMETLLSSNAS 1728
Cdd:PRK03918   264 LEERIEELKKEIEELEEKVkelkelkekaeeyiklSEFYEEYLDELREIEKRLSRLEEEI--------NGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1729 MKEELERVKMEYETLSKKFQSLmSEKDSLSEEVQDLKHQIEGNVSKQANL---EATEKHDNQTNVTEEGTQSIPGETEEQ 1805
Cdd:PRK03918   336 KEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTGLtpeKLEKELEELEKAKEEIEEEISKITARI 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1806 DSLS--MSTRPTCSESVPSAKSANPAVSKDFSSHDE---INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN---T 1877
Cdd:PRK03918   415 GELKkeIKELKKAIEELKKAKGKCPVCGRELTEEHRkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKkesE 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1878 LLSQISTKDgELKMLQEEVTKMNLlnqqiqEELSRVTKLKETAEEEKDDLEERLMNQLAELNgsignycqdvtdaqiKNE 1957
Cdd:PRK03918   495 LIKLKELAE-QLKELEEKLKKYNL------EELEKKAEEYEKLKEKLIKLKGEIKSLKKELE---------------KLE 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1958 LLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIqgaqkepgnkshaKELQELLKEkQQEVKQLQKDCIRYQ 2037
Cdd:PRK03918   553 ELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL-------------KELEPFYNE-YLELKDAEKELEREE 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2038 EKISALERTVKALEFVQTESQKDLEITKENLAQAveHRKKAQAELASFKVLLDDTQSEAARVLADnlklKKELQSNKESV 2117
Cdd:PRK03918   619 KELKKLEEELDKAFEELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAE----LEELEKRREEI 692

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1483569506 2118 KSQMKQKDEDLERRLEQAEEKHLKEK--KNMQEKLDALRREKVHLEE 2162
Cdd:PRK03918   693 KKTLEKLKEELEEREKAKKELEKLEKalERVEELREKVKKYKALLKE 739
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 994-1598 6.26e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 6.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  994 EQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEiplsETERGEVEEDKENkeysekcvtskcqeieiyLKQTISE 1073
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEEL----EAELAELEAELEE------------------LRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1074 KEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSntdasdgdsvalvketvvis 1153
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE-------------------- 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1154 ppctgssehwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQ----------KDDYNRLQEQ 1223
Cdd:COG1196    339 ----------LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELlealraaaelAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1224 FDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASAL 1303
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL--------LEAALA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1304 QGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKK-----SEEVFQLQEQINKQGLEIE-----SLKTVSHEAEVHAE 1373
Cdd:COG1196    481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglAGAVAVLIGVEAAYEAALEaalaaALQNIVVEDDEVAA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1374 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAK 1453
Cdd:COG1196    561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1454 EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVS 1533
Cdd:COG1196    641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 1534 AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQslssscESLKLALEGLTEDKEKLVKEIESL 1598
Cdd:COG1196    721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEE------LPEPPDLEELERELERLEREIEAL 779
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1952-2708 7.52e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 7.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1952 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2031
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2032 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2111
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2112 SNKESVKSQMKQKDEDLERRL------EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2186 dstvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHD 2265
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2266 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK--DQLTDLSNSLEKCKEQKGNL 2343
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2344 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS 2423
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2424 QEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLI 2503
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2504 QEAAAE--NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKL 2581
Cdd:pfam02463  727 VQEAQDkiNEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2582 KESEEANEDLRRSFNALQE-EKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEvhrlsalfsSSQKRI 2660
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEqEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQE---------LLLKEE 877

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1483569506 2661 AELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEE 2708
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKE 925
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 327-1142 8.76e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 8.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  327 EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHkaemEEKTSHILSLQKTGQELQSACDALKdq 406
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEIEELQKELYALA-- 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  407 nsKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQtsfpdvynEGTQAVTEENIASLQKRVVELE 486
Cdd:TIGR02168  295 --NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL--------EEKLEELKEELESLEAELEELE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  487 NEKGALLLSSIELEElkaENEKLSSQITLLEAQNRTGEADREVSEISIVDIA---NKRSSSAEESGQDVLENTFSQKHKE 563
Cdd:TIGR02168  365 AELEELESRLEELEE---QLETLRSKVAQLELQIASLNNEIERLEARLERLEdrrERLQQEIEELLKKLEEAELKELQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  564 LSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEgEGIAPIKMKVFLEDTGQDFPlmpneESSLPAVEKE 643
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLEGFS-----EGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  644 QASTEHQSRTSEEISLnDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKsqilelELNFHKAQEIYEKNLDEKAKEI 723
Cdd:TIGR02168  516 SGLSGILGVLSELISV-DEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLK------QNELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  724 SNLNQL--IEEFKKNADNNSSAFTALSEERDQLLSQVKelsMVTelraqvkqlemNLAEAERQRRLDYESQtahdNLLTE 801
Cdd:TIGR02168  589 NDREILknIEGFLGVAKDLVKFDPKLRKALSYLLGGVL---VVD-----------DLDNALELAKKLRPGY----RIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  802 QIHSLSIE------AKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVlegaervrhisskvEELSQALSQ 875
Cdd:TIGR02168  651 DGDLVRPGgvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL--------------EELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  876 KELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQlnllsraeEAKKEQVE 955
Cdd:TIGR02168  717 LRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA--------EAEIEELE 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  956 EDNEVSSGLKQNYDEMSpagqiskEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLkdesKKEIPLS 1035
Cdd:TIGR02168  789 AQIEQLKEELKALREAL-------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL----SEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1036 ETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL---VKQMNQTLQDKTNQ 1112
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELrekLAQLELRLEGLEVR 937

                          810       820       830
                   ....*....|....*....|....*....|
gi 1483569506 1113 IDLLQAEISENQAIIQKLITSNTDASDGDS 1142
Cdd:TIGR02168  938 IDNLQERLSEEYSLTLEEAEALENKIEDDE 967
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1421-2914 8.89e-07

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.44  E-value: 8.89e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1421 SEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIGEE----SRAKQQIQRKLQAaLIS 1496
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELE----EENEDSIHLEKEIKDLFDKYLEIDDEiiyiNKLKLELKEKIKN-ISD 614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1497 RKEALKENKSLQEELSLARGTIERLTK-SLADVESQVSAQNKEKDTVLGRLA-LLQEERDKLITEMDRSLLENQSLSssc 1574
Cdd:TIGR01612  615 KNEYIKKAIDLKKIIENNNAYIDELAKiSPYQVPEHLKNKDKIYSTIKSELSkIYEDDIDALYNELSSIVKENAIDN--- 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1575 eslklaleglTEDKEKLvkeiESLKSSKIAESTEWQEKHKELQKEYeilLQSYENVSNEAERIqhVVEAVRQEKQELYGK 1654
Cdd:TIGR01612  692 ----------TEDKAKL----DDLKSKIDKEYDKIQNMETATVELH---LSNIENKKNELLDI--IVEIKKHIHGEINKD 752

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1655 LRSTEANKKETEKQLQEAEQEMEEMKEKMRKFakskQQKILELEEE-NDRLR------AEVHPAGDTAKECMETLLSSNA 1727
Cdd:TIGR01612  753 LNKILEDFKNKEKELSNKINDYAKEKDELNKY----KSKISEIKNHyNDQINidnikdEDAKQNYDKSKEYIKTISIKED 828

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1728 SMKEELERVK-MEYETLSK-----KFQSLMSEK-DSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIpg 1800
Cdd:TIGR01612  829 EIFKIINEMKfMKDDFLNKvdkfiNFENNCKEKiDSEHEQFAELTNKIKAEISDDKLNDYEKKFNDSKSLINEINKSI-- 906

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1801 eteEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQ-IDQLKEriAGLEEEKQKNKeFSQTLENEKNTL- 1878
Cdd:TIGR01612  907 ---EEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKnIDTIKE--SNLIEKSYKDK-FDNTLIDKINELd 980

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1879 -------LSQISTKDGEL----KMLQEEV--TKMNLLNQQIQEELSRVTKLketaEEEKDDLEERLMNQLAELNGSIGNY 1945
Cdd:TIGR01612  981 kafkdasLNDYEAKNNELikyfNDLKANLgkNKENMLYHQFDEKEKATNDI----EQKIEDANKNIPNIEIAIHTSIYNI 1056

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1946 CQDVTDAQIKN-ELLESE-MKNLKKCVSELEEEKQQL----VKEKTKVESEIRKEYLEKIQGAQKEPGNK--SHAKELQE 2017
Cdd:TIGR01612 1057 IDEIEKEIGKNiELLNKEiLEEAEINITNFNEIKEKLkhynFDDFGKEENIKYADEINKIKDDIKNLDQKidHHIKALEE 1136

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2018 LLKEKQQEVKQLQKdciryqeKISALERTvkALEFVQTESQKDLEITKENLAQAVEHRKKAQAELasfKVLLddtqSEAA 2097
Cdd:TIGR01612 1137 IKKKSENYIDEIKA-------QINDLEDV--ADKAISNDDPEEIEKKIENIVTKIDKKKNIYDEI---KKLL----NEIA 1200

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2098 RVLADNLKLKK----ELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV-- 2169
Cdd:TIGR01612 1201 EIEKDKTSLEEvkgiNLSYGKNLGKLFLEKIDEEKKKseHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETfn 1280

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2170 TLNKKDKEVQQLQENLDSTVTQLAafTKSMSSLQDD-RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLkdqlrqm 2248
Cdd:TIGR01612 1281 ISHDDDKDHHIISKKHDENISDIR--EKSLKIIEDFsEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANI------- 1351

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2249 sihmeelkINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyhSSQNELAKLESELKSLKDQLtd 2328
Cdd:TIGR01612 1352 --------YNILKLNKIKKIID-------------------EVKEYTKEIEENNK---NIKDELDKSEKLIKKIKDDI-- 1399

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2329 lsnSLEKCKEQkgnLEGIIRQQEAD--IQNSKFSYEQL---ETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVA 2403
Cdd:TIGR01612 1400 ---NLEECKSK---IESTLDDKDIDecIKKIKELKNHIlseESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIK 1473

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2404 IAELRQQHDKEIKELENLLSQEEEENIVLEEeNKKAVDKTNQLMETLKTIKKENIQQKAQLdSFVKSMSSLQNDRDRIVg 2483
Cdd:TIGR01612 1474 KDNATNDHDFNINELKEHIDKSKGCKDEADK-NAKAIEKNKELFEQYKKDVTELLNKYSAL-AIKNKFAKTKKDSEIII- 1550

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2484 dyQQLEERHLSIILE------------KDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDaeliQYREDLNQVIT 2550
Cdd:TIGR01612 1551 --KEIKDAHKKFILEaekseqkikeikKEKFrIEDDAAKNDKSNKAAIDIQLSLENFENKFLKIS----DIKKKINDCLK 1624

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2551 IKDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEdlRRSFNALQEEKQDLSKEIESLKVSISQLTRQVtalqE 2628
Cdd:TIGR01612 1625 ETESIEKKIssFSIDSQDTELKENGDNLNSLQEFLESLKDQ--KKNIEDKKKELDELDSEIEKIEIDVDQHKKNY----E 1698

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2629 EGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEE 2708
Cdd:TIGR01612 1699 IGIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSK 1778

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2709 R---VAELARDLVEMEQKLLMVTKENKGLTA-----QIQSFGRSMSSLQNSRDHAN----EELDELKRKYDASLKELAQL 2776
Cdd:TIGR01612 1779 EpitYDEIKNTRINAQNEFLKIIEIEKKSKSylddiEAKEFDRIINHFKKKLDHVNdkftKEYSKINEGFDDISKSIENV 1858

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2777 KEQ-------GLLNRERDAL---------------------LSETAFSMNSTEENS--LSHLEKLNQQLLSkdeqllHLS 2826
Cdd:TIGR01612 1859 KNStdenllfDILNKTKDAYagiigkkyysykdeaekifinISKLANSINIQIQNNsgIDLFDNINIAILS------SLD 1932

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2827 SQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSA---------AQPSTSPAEVQSLKKAMSSLQNDRDR 2897
Cdd:TIGR01612 1933 SEKEDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQdtlniifenQQLYEKIQASNELKDTLSDLKYKKEK 2012

                         1610
                   ....*....|....*..
gi 1483569506 2898 LLKELKNLQQQYLQINQ 2914
Cdd:TIGR01612 2013 ILNDVKLLLHKFDELNK 2029
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 151-1020 9.27e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.07  E-value: 9.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  151 HKLQEKEELISTLQAQLTQAQAEQpAQSSTEMEEFVmmkQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREKDAR 230
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEEEL-EKLTEEISELE---KRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIAS 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  231 FETQVRLHEDELLQLVTQadvETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNT 310
Cdd:TIGR02169  306 LERSIAEKERELEDAEER---LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  311 LRNTVETEREESKILLEKMElevaerklsfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQ 390
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREIN-----------ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIK 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  391 KTGQELQSACDALKDQNSKLLQDKNEqavqsaqtIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAV 470
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEE--------YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGV 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  471 ---TEENIASLQKRVVELENEKGAlllssiELEELKAENEKLSSQITLLEAQNRTGEAdrevSEISIVDIANKRSSSAEE 547
Cdd:TIGR02169  524 hgtVAQLGSVGERYATAIEVAAGN------RLNNVVVEDDAVAKEAIELLKRRKAGRA----TFLPLNKMRDERRDLSIL 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  548 SGQDVLEntfsqkhkeLSVLLLEMKEAQEEIAFLKLQLQG-KRAEEADHEVLDQKEMKQMEGEgiapikmkvFLEDTGqd 626
Cdd:TIGR02169  594 SEDGVIG---------FAVDLVEFDPKYEPAFKYVFGDTLvVEDIEAARRLMGKYRMVTLEGE---------LFEKSG-- 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  627 fpLMPNEESSLPAVEKEQASTEHQSRtseeislndagvELKSTKQDGDKSLSAVpdigqchQDELERLKSQILELELNFH 706
Cdd:TIGR02169  654 --AMTGGSRAPRGGILFSRSEPAELQ------------RLRERLEGLKRELSSL-------QSELRRIENRLDELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  707 KAqeiyEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEMNLAEAERQR 785
Cdd:TIGR02169  713 DA----SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELeARIEELEEDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  786 RLDYESQtahdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSK 865
Cdd:TIGR02169  789 SHSRIPE------IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGK 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  866 VEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEekfsLGVEIKTLKEQLNLLSR 945
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSE----LKAKLEALEEELSEIED 938

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1483569506  946 AEEAKKEQVEED---NEVSSGLKQNYDEMSPAGQISKEELQhEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE 1020
Cdd:TIGR02169  939 PKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNMLAIQ-EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1313-1923 1.02e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 1.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1313 KAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHL 1392
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1393 RELQPKLDELQKLISKKeedVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1472
Cdd:TIGR04523  203 LSNLKKKIQKNKSLESQ---ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1473 PEEIGEESRAKQQIQRKLQAAlisrkealkENKSLQEELSLARGTIERLTKSLADVESQVSAQNKekdtvlgRLALLQEE 1552
Cdd:TIGR04523  280 NKKIKELEKQLNQLKSEISDL---------NNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNK-------IISQLNEQ 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1553 RDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKiaestewqekhkelqKEYEILLQSYENVSN 1632
Cdd:TIGR04523  344 ISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQI---------------NDLESKIQNQEKLNQ 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1633 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKIleleeendrlraevhpag 1712
Cdd:TIGR04523  409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL------------------ 470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1713 dtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTnvte 1792
Cdd:TIGR04523  471 -------KVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESK---- 539

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1793 egTQSIPGETEEQDSlsmstrptcsesvpsaksanpaVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLE 1872
Cdd:TIGR04523  540 --ISDLEDELNKDDF----------------------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKE 595

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1483569506 1873 NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEE 1923
Cdd:TIGR04523  596 KEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQE 646
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1311-2158 1.10e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 1.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1311 QIKAQLKEIEAEKvELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLES----SQLQI 1386
Cdd:TIGR00606  225 QITSKEAQLESSR-EIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1387 AGLEH-----LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTK-------IQTEIIEQEDLIKALHTQLEMQAKE 1454
Cdd:TIGR00606  304 NDLYHnhqrtVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRlqlqadrHQEHIRARDSLIQSLATRLELDGFE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1455 HDERIKQLQVELCEMKQKPEEigEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLARGTIERLTKSLADVESQvsa 1534
Cdd:TIGR00606  384 RGPFSERQIKNFHTLVIERQE--DEAKTAAQLCADLQSKERLKQEQADE---IRDEKKGLGRTIELKKEILEKKQEE--- 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1535 qnkekdtvlgrLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALE-GLTEDKEKLVKEIESLKSSKIAESTEWQEKH 1613
Cdd:TIGR00606  456 -----------LKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKnSLTETLKKEVKSLQNEKADLDRKLRKLDQEM 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1614 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLrSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQk 1693
Cdd:TIGR00606  525 EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLL-GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELAS- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1694 ileLEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEE--LERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGN 1771
Cdd:TIGR00606  603 ---LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEEsdLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSC 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1772 VSKQANLEATEKHDNQ-TNVTEEGTQSIPGETEEQDSLSMSTRptcsesvpsaKSANPAVSKDFSSHDEINNYLQQIDQL 1850
Cdd:TIGR00606  680 CPVCQRVFQTEAELQEfISDLQSKLRLAPDKLKSTESELKKKE----------KRRDEMLGLAPGRQSIIDLKEKEIPEL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1851 KERIAGLEEEKQKNKEFSQtlenEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE--------- 1921
Cdd:TIGR00606  750 RNKLQKVNRDIQRLKNDIE----EQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQgsdldrtvq 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1922 ------EEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1995
Cdd:TIGR00606  826 qvnqekQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIK 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1996 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKEN-------- 2067
Cdd:TIGR00606  906 DAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETelntvnaq 985

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2068 LAQAVEHRKKAQAELASFKVLLdDTQSEAARVLADNLKLKK---ELQSNKESVKSQMKQKDEDLERRLEQAEEKhlkekk 2144
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQDI-DTQKIQERWLQDNLTLRKrenELKEVEEELKQHLKEMGQMQVLQMKQEHQK------ 1058

                          890
                   ....*....|....
gi 1483569506 2145 nMQEKLDALRREKV 2158
Cdd:TIGR00606 1059 -LEENIDLIKRNHV 1071
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1300-1536 2.71e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 2.71e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1300 ASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKL 1379
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1380 ESSQLQIAGLEHlrELQPKLDELQKLISKKEEDV---SYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHD 1456
Cdd:COG4942     93 AELRAELEAQKE--ELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1457 ERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELslaRGTIERLTKSLADVESQVSAQN 1536
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL---EALIARLEAEAAAAAERTPAAG 247
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1332-2263 3.17e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.51  E-value: 3.17e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1332 STTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEE 1411
Cdd:TIGR00606  166 SEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYEN 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1412 DVSYLSGQLSEKEAALTKIQteiiEQEDLIKALH-TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKL 1490
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIM----KLDNEIKALKsRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKEREL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1491 QAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLIT------------ 1558
Cdd:TIGR00606  322 VDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErqiknfhtlvie 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1559 -EMDRSLLENQSLSSSCESLKLALEGLTE--------------DKEKLVKEIESLKSSK------IAESTEWQEKHKELQ 1617
Cdd:TIGR00606  402 rQEDEAKTAAQLCADLQSKERLKQEQADEirdekkglgrtielKKEILEKKQEELKFVIkelqqlEGSSDRILELDQELR 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1618 KEYEILLQSYENVSNEAERIQhvVEAVRQEKQELYGKLRSTEanKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILEL 1697
Cdd:TIGR00606  482 KAERELSKAEKNSLTETLKKE--VKSLQNEKADLDRKLRKLD--QEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSR 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1698 EEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1777
Cdd:TIGR00606  558 HSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1778 LEATEKHDNQTNVTEEGTQSIPGETEEQDSLsmstrptCSESVPSAKSANPAVSKDFSSHDEINNYlqqIDQLKERIAGL 1857
Cdd:TIGR00606  638 ESDLERLKEEIEKSSKQRAMLAGATAVYSQF-------ITQLTDENQSCCPVCQRVFQTEAELQEF---ISDLQSKLRLA 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1858 EEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDL--EERLMNQL 1935
Cdd:TIGR00606  708 PDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpEEESAKVC 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1936 AELNGSIGNYCQDVTDAQIKNELLESEMK--NLKKCVSELEEEKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPG 2007
Cdd:TIGR00606  788 LTDVTIMERFQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIElnrkliQDQQEQIQHLKSKTN 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2008 N-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAElasfk 2086
Cdd:TIGR00606  868 ElKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK----- 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2087 vlLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALrrEKVHLEETIGE 2166
Cdd:TIGR00606  943 --VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI--DTQKIQERWLQ 1018

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2167 IQVTLNKKDKEVQQLQENLDSTVTQLAAF-TKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEI-----RLKEDNCSV 2240
Cdd:TIGR00606 1019 DNLTLRKRENELKEVEEELKQHLKEMGQMqVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIkhfkkELREPQFRD 1098

                          970       980
                   ....*....|....*....|...
gi 1483569506 2241 LKDQLRQMSIHMEELKINISRLE 2263
Cdd:TIGR00606 1099 AEEKYREMMIVMRTTELVNKDLD 1121
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1384-1659 3.25e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 53.01  E-value: 3.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1384 LQIAGLEhlRELQPKLDELQKL-----ISKKEED----VSYLSGQLSEKEAALTKIQTeIIEQEDLIKALhtQLEMQAKE 1454
Cdd:PRK05771     9 VLIVTLK--SYKDEVLEALHELgvvhiEDLKEELsnerLRKLRSLLTKLSEALDKLRS-YLPKLNPLREE--KKKVSVKS 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1455 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQaaliSRKEALKENKSLQEELSLAR---------GTI-----ER 1520
Cdd:PRK05771    84 LEELIKDVEEELEKIEKEIKELEEEISELENEIKELE----QEIERLEPWGNFDLDLSLLLgfkyvsvfvGTVpedklEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1521 LTKSLADVESQVSAQNKEKDTVLgrLALLQEERDKLITEMDRSLLENQSLSSScESLKLALEGLTEDKEKLVKEIESLKs 1600
Cdd:PRK05771   160 LKLESDVENVEYISTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESLL- 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1483569506 1601 SKIAESTEwqekhkelqKEYEILLQSYENVSNEAERiqhvveavrqekQELYGKLRSTE 1659
Cdd:PRK05771   236 EELKELAK---------KYLEELLALYEYLEIELER------------AEALSKFLKTD 273
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2356-3014 3.48e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 3.48e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2356 NSKFSYEQLETDLQaSRELTSRLHEEINMKEQKiisllsgkeEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEE 2435
Cdd:TIGR02169  208 EKAERYQALLKEKR-EYEGYELLKEKEALERQK---------EAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2436 NKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2515
Cdd:TIGR02169  278 NKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2516 EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEAnEDLRRSF 2595
Cdd:TIGR02169  358 EYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI-AGIEAKI 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2596 NALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-----GTLGLYHAQLKVKEEEVHRLSALFSSSQKR----------- 2659
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQElydlkEEYDRVEKELSKLQRELAEAEAQARASEERvrggraveevl 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2660 ----------IAEL------------------------EEELV---CVQKEAAKKVG----------------------- 2679
Cdd:TIGR02169  517 kasiqgvhgtVAQLgsvgeryataievaagnrlnnvvvEDDAVakeAIELLKRRKAGratflplnkmrderrdlsilsed 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2680 ----------EIEDKLKKELKHLHHDAGIMRNeTETAEE-----RVAELARDLVE----------MEQKLLMVTKENKG- 2733
Cdd:TIGR02169  597 gvigfavdlvEFDPKYEPAFKYVFGDTLVVED-IEAARRlmgkyRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAe 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2734 ---LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQL-KEQGLLNRERDALLSETafsmnsteENSLSHLE 2809
Cdd:TIGR02169  676 lqrLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERL--------EELEEDLS 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2810 KLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHlwnelEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMS 2889
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-----SRIPEIQAELSKLEEEVSRIEARLREIEQKLN 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2890 SLQNDRDRLLKELKNLQQQYL----QINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWE 2965
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIdlkeQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELE 902

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2966 IHERRMKEQY----------LMAISDKDQQLSHLQNLIRELRSSSSQTQPL-KVQYQRQA 3014
Cdd:TIGR02169  903 RKIEELEAQIekkrkrlselKAKLEALEEELSEIEDPKGEDEEIPEEELSLeDVQAELQR 962
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
208-384 3.91e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 3.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  208 QTQAEQAAQLssmqQVVREKDARFEtQVRLHEDELLQLVTQADVETEmQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 287
Cdd:COG4913    245 EDAREQIELL----EPIRELAERYA-AARERLAELEYLRAALRLWFA-QRRLELLEAELEELRAELARLEAELERLEARL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  288 TAAEQ-----RNQILS---QQLQQMEAEHNTL---RNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQ 356
Cdd:COG4913    319 DALREeldelEAQIRGnggDRLEQLEREIERLereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEE 398

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1483569506  357 ----AGQAQAELESRYSALEQKHKAEMEEKTS 384
Cdd:COG4913    399 eleaLEEALAEAEAALRDLRRELRELEAEIAS 430
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 35-621 4.44e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 4.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   35 HQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEM 114
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  115 KAQG--------------------------------GTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHK-LQEKEELIS 161
Cdd:pfam15921  155 EAAKclkedmledsntqieqlrkmmlshegvlqeirSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKiLRELDTEIS 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  162 TLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEK-EEFISTLQAQLS------QTQAEQAAQLSSMQQVVREKDARFETQ 234
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRiEQLISEHEVEITgltekaSSARSQANSIQSQLEIIQEQARNQNSM 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  235 VRLHEDELLQLVTQadVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNT 314
Cdd:pfam15921  315 YMRQLSDLESTVSQ--LRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  315 VETEREESKILLEK-----MELEVAERKLSFHNLQ-EEMHHLLEQFEQagQAQAELESRYSALEQKHKAeMEEKTSHILS 388
Cdd:pfam15921  393 LSLEKEQNKRLWDRdtgnsITIDHLRRELDDRNMEvQRLEALLKAMKS--ECQGQMERQMAAIQGKNES-LEKVSSLTAQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  389 LQKTGQELQSACDALKDQnsKLLQDKNEQAVQS-AQTIQQLEDQLQQKSKEISQFLNRLPLQ----QHETASQTSFPDVY 463
Cdd:pfam15921  470 LESTKEMLRKVVEELTAK--KMTLESSERTVSDlTASLQEKERAIEATNAEITKLRSRVDLKlqelQHLKNEGDHLRNVQ 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  464 NE---------GTQAVTE---ENIASLQKRVVELENEKGALLLSS-----------IELEELKAENEKLSSQITLLEAQn 520
Cdd:pfam15921  548 TEcealklqmaEKDKVIEilrQQIENMTQLVGQHGRTAGAMQVEKaqlekeindrrLELQEFKILKDKKDAKIRELEAR- 626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  521 rtgEADREVSEISIVDIANKRSSSAEESGQ--DVLENTFSQKHKELSVLLLEM---------KEAQEEIAFLKLQLQGKR 589
Cdd:pfam15921  627 ---VSDLELEKVKLVNAGSERLRAVKDIKQerDQLLNEVKTSRNELNSLSEDYevlkrnfrnKSEEMETTTNKLKMQLKS 703

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1483569506  590 AEEADHEVldQKEMKQMEGEGIAPIKMKVFLE 621
Cdd:pfam15921  704 AQSELEQT--RNTLKSMEGSDGHAMKVAMGMQ 733
PTZ00121 PTZ00121
MAEBL; Provisional
 945-1649 6.73e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 6.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  945 RAEEAKK-EQVEEDNEVSSGLK-------QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 1016
Cdd:PTZ00121  1177 KAEAARKaEEVRKAEELRKAEDarkaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK 1256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1017 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE-QF 1095
Cdd:PTZ00121  1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAaKK 1336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1096 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNtDASDGDSVALVKETVVISPPCTGSSEHWKPELEE--KILA 1173
Cdd:PTZ00121  1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE-AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElkKAAA 1415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1174 LEKEKEQLQKKLQEAltsRKAILKKAQEKERHLREELKQQKDDYNRLQEQfdEQSKENENIGDQLRQLQIQVRESIDGKL 1253
Cdd:PTZ00121  1416 AKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEA--KKKAEEAKKADEAKKKAEEAKKADEAKK 1490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1254 PSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESnlcpDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVElelkvsst 1333
Cdd:PTZ00121  1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELK-------- 1558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1334 TSELTKKSEEVFQLQEQINKQGLEIESLKTVshEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELqklisKKEEDV 1413
Cdd:PTZ00121  1559 KAEEKKKAEEAKKAEEDKNMALRKAEEAKKA--EEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL-----KKAEEE 1631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1414 SYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQ--RKLQ 1491
Cdd:PTZ00121  1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEelKKKE 1711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1492 AALISRKEALK------------------ENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRlaLLQEER 1553
Cdd:PTZ00121  1712 AEEKKKAEELKkaeeenkikaeeakkeaeEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE--ELDEED 1789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1554 DKLITEMDRSLLENQSLSSSCES----LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYEN 1629
Cdd:PTZ00121  1790 EKRRMEVDKKIKDIFDNFANIIEggkeGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869

                          730       740
                   ....*....|....*....|
gi 1483569506 1630 VSNEAERIQHVVEAVRQEKQ 1649
Cdd:PTZ00121  1870 FNKEKDLKEDDEEEIEEADE 1889
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2501-2909 7.12e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 7.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2501 QLIQEAAAENNKLKEEIRGLrshmDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELEnkyakleek 2580
Cdd:TIGR02169  146 DFISMSPVERRKIIDEIAGV----AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--------- 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2581 lkeseeanedlrrsFNALQEEKQD-----LSKEIESLKVSISQLTRQVTALqeegtlglyhaqlkvkEEEVHRLSALFSS 2655
Cdd:TIGR02169  213 --------------YQALLKEKREyegyeLLKEKEALERQKEAIERQLASL----------------EEELEKLTEEISE 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2656 SQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHhdagimrNETETAEERVAELARDLVEMEQKLLMVTKENKGLT 2735
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELE-------AEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2736 AQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAfsmnsteENSLSHLEKLNQQL 2815
Cdd:TIGR02169  336 AEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL-------EKLKREINELKREL 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2816 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKfrksEEGKQRSAAqpstspAEVQSLKKAMSSLQNDR 2895
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK----QEWKLEQLA------ADLSKYEQELYDLKEEY 478

                          410
                   ....*....|....
gi 1483569506 2896 DRLLKELKNLQQQY 2909
Cdd:TIGR02169  479 DRVEKELSKLQREL 492
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1395-1940 7.88e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 7.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1395 LQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQT--EIIEQ----------------EDLIKALHTQLEMQAKEHD 1456
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSqlEIIQEqarnqnsmymrqlsdlESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1457 ERIKQLQ-------VELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL----KENKSLQEELSLARGTIERLTKSL 1525
Cdd:pfam15921  342 DKIEELEkqlvlanSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELslekEQNKRLWDRDTGNSITIDHLRREL 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1526 ADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAE 1605
Cdd:pfam15921  422 DDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDL 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1606 STEWQEKHK----------ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ---EA 1672
Cdd:pfam15921  502 TASLQEKERaieatnaeitKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQH 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1673 EQEMEEMKEKMRKFAKSKQQKILELEE-------ENDRLRAEVHPAGDTAKECMEtLLSSNASMKEELERVKMEYETLSK 1745
Cdd:pfam15921  582 GRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkKDAKIRELEARVSDLELEKVK-LVNAGSERLRAVKDIKQERDQLLN 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1746 KFQSLMSEKDSLSEEVQDLKHQIEGNvskqanleaTEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKS 1825
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLKRNFRNK---------SEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMG 731

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1826 ANPAVSKDFSSHDEINNYLQQIDQL-----KERiAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMN 1900
Cdd:pfam15921  732 MQKQITAKRGQIDALQSKIQFLEEAmtnanKEK-HFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1483569506 1901 LLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNG 1940
Cdd:pfam15921  811 VALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2115-2797 8.43e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 8.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2115 ESVKSQMKQKDEDLERRLEQAEEKHLKEK--------------KNMQEKLDAL----RREKVHLEETIGEIQVTLNKKDK 2176
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKfylrqsvidlqtklQEMQMERDAMadirRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2177 EVQQLQENLDSTVTQLAAFTKSMSS----LQDDRDRVIDEAKKWERKFSDAIQSKEEEIRlkeDNCSVLKDQLRQMSIHM 2252
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLShegvLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---SLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2253 EELKINISRLEHDKQIWESKAQTEVQL----QQKVCDTLQGENKELLSQLEETRHlyhSSQNELAKLESELKSLKDQLTD 2328
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNKIELllqqHQDRIEQLISEHEVEITGLTEKAS---SARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2329 lSNSLEKCkeQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ-----ASRELTSRLHEEINMKE---------QKIISLLS 2394
Cdd:pfam15921  311 -QNSMYMR--QLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlANSELTEARTERDQFSQesgnlddqlQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2395 GKEEAIQ-----------------VAIAELRQQHDK---EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIK 2454
Cdd:pfam15921  388 KREKELSlekeqnkrlwdrdtgnsITIDHLRRELDDrnmEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLT 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2455 KENIQQKAQLDSFVKSMSSLQ---NDRDRIVGDYQqleerhlSIILEKDQLIQEAAAENNKLK-------EEIRGLRSHM 2524
Cdd:pfam15921  468 AQLESTKEMLRKVVEELTAKKmtlESSERTVSDLT-------ASLQEKERAIEATNAEITKLRsrvdlklQELQHLKNEG 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2525 DDLNSENAKLDAELIQYREDlNQVITIKDSQQKQLLEVQLQQNKELenkyAKLEEKLKESEEANEDLRRSFNALQEEKQD 2604
Cdd:pfam15921  541 DHLRNVQTECEALKLQMAEK-DKVIEILRQQIENMTQLVGQHGRTA----GAMQVEKAQLEKEINDRRLELQEFKILKDK 615

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2605 LSKEIESLKVSISQLTRQVTALQEEGTLGLyHAQLKVKEEEVHRLSALfSSSQKRIAELEEELVCVQKEAAKKVGEIE-- 2682
Cdd:pfam15921  616 KDAKIRELEARVSDLELEKVKLVNAGSERL-RAVKDIKQERDQLLNEV-KTSRNELNSLSEDYEVLKRNFRNKSEEMEtt 693

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2683 -DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2761
Cdd:pfam15921  694 tNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNK 773

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 1483569506 2762 LKRKYDASLKELAQLKEQGLLNRERDALLSETAFSM 2797
Cdd:pfam15921  774 LSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809
PRK11281 PRK11281
mechanosensitive channel MscK;
151-513 9.70e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.84  E-value: 9.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  151 HKLQEKEEliSTLQAQLTQAQA--EQPAQSSTEMEEfvmMKQQLQEkeefistLQAQLSQTQAEQAAQLSSMQQVVREkd 228
Cdd:PRK11281    51 QKLLEAED--KLVQQDLEQTLAllDKIDRQKEETEQ---LKQQLAQ-------APAKLRQAQAELEALKDDNDEETRE-- 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  229 aRFETqvrLHEDELLQLVTQadVETEMQQklrvLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEH 308
Cdd:PRK11281   117 -TLST---LSLRQLESRLAQ--TLDQLQN----AQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLKGGKVGG 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  309 NTLRNTVETERE------ESKILLEKMELEVAERKLSFHNLQeemHHLLEqfEQAGQAQAELESRYSALEQKHKAEMEek 382
Cdd:PRK11281   187 KALRPSQRVLLQaeqallNAQNDLQRKSLEGNTQLQDLLQKQ---RDYLT--ARIQRLEHQLQLLQEAINSKRLTLSE-- 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  383 tshilslqKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQT-IQQLE--DQLQQKSKEISQFLNRlpLQQhetasqtsf 459
Cdd:PRK11281   260 --------KTVQEAQSQDEAARIQANPLVAQELEINLQLSQRlLKATEklNTLTQQNLRVKNWLDR--LTQ--------- 320

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1483569506  460 pdvynegTQAVTEENIASLQkrvvelenekGALLLSSIELEELKA-----ENEKLSSQI 513
Cdd:PRK11281   321 -------SERNIKEQISVLK----------GSLLLSRILYQQQQAlpsadLIEGLADRI 362
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2396-3161 1.06e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 1.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2396 KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDsfvKSMSSLQ 2475
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELE---KLTEEIS 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2476 NDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQ 2555
Cdd:TIGR02169  262 ELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2556 QKQLLEVQLQQNK------ELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLtrQVTALQEE 2629
Cdd:TIGR02169  342 EREIEEERKRRDKlteeyaELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL--QEELQRLS 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2630 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqKEAAKKVGEIEDKLKKelkhlhhdagiMRNETETAEER 2709
Cdd:TIGR02169  420 EELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL----EQLAADLSKYEQELYD-----------LKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2710 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRdhanEELDELKRKYDASLkELAQLKEQGLLNRERDAL 2789
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTV----AQLGSVGERYATAI-EVAAGNRLNNVVVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2790 LSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQV---QSFSKA----------MASLQNERDHLWN- 2855
Cdd:TIGR02169  560 AKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVefdPKYEPAfkyvfgdtlvVEDIEAARRLMGKy 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2856 -----ELEKFRKS------EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH---- 2920
Cdd:TIGR02169  640 rmvtlEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASrkig 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2921 PLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLR--MEKSSWEIHERRMK-EQYLMAISDKDQQLSH--------- 2988
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKseLKELEARIEELEEDlHKLEEALNDLEARLSHsripeiqae 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2989 LQNLIRELRSSSSQTQPLKVQYQRQASPETSASpDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKN 3068
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE-KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 3069 TLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQL 3148
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQA 958

                          810
                   ....*....|...
gi 1483569506 3149 CNTRQEVnELRKL 3161
Cdd:TIGR02169  959 ELQRVEE-EIRAL 970
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2298-3062 1.10e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2298 LEETRHLYHSSQ---NELAKLESELK-SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2373
Cdd:pfam15921   80 LEEYSHQVKDLQrrlNESNELHEKQKfYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKC 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2374 LTSRLHEEINMKEQKIISLLSGKE---EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETl 2450
Cdd:pfam15921  160 LKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG- 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2451 KTIKKENIQQKAQLDSFVKSMSSLQNDRDRIvgdyQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNS- 2529
Cdd:pfam15921  239 RIFPVEDQLEALKSESQNKIELLLQQHQDRI----EQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSm 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2530 ---ENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2606
Cdd:pfam15921  315 ymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELS 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2607 KEIESLKVSISQLTRQVTalqeegTLGLYHAQLKVKEEEVHRLSALFSSSQKRI-AELEEELVCVQ--KEAAKKVGEIED 2683
Cdd:pfam15921  395 LEKEQNKRLWDRDTGNSI------TIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQgkNESLEKVSSLTA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2684 KLkkelkhlhhdagimrnetETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSlqnsrdhANEELDELK 2763
Cdd:pfam15921  469 QL------------------ESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEA-------TNAEITKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2764 RKYDASLKELAQLKEQGllnrerDALlsetafsmnsteENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAM 2843
Cdd:pfam15921  524 SRVDLKLQELQHLKNEG------DHL------------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTA 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2844 ASLQNERDHLWNELE---------KFRKSEEGKQRSAAQPSTSPAEVQSLK---------KAMSSLQNDRDRLLKELKNL 2905
Cdd:pfam15921  586 GAMQVEKAQLEKEINdrrlelqefKILKDKKDAKIRELEARVSDLELEKVKlvnagserlRAVKDIKQERDQLLNEVKTS 665

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2906 QQQYLQINQEITELHplkaqlQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWE---IHERRMKEQYLMAISDK 2982
Cdd:pfam15921  666 RNELNSLSEDYEVLK------RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdGHAMKVAMGMQKQITAK 739

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2983 DQQLSHLQNLIR---ELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSN 3059
Cdd:pfam15921  740 RGQIDALQSKIQfleEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQ 819


                   ...
gi 1483569506 3060 FSQ 3062
Cdd:pfam15921  820 FAE 822
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 242-458 1.13e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  242 LLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLR---NTVETE 318
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  319 REESKILLEKMELEVAE--RKLSFHNLQEEMHHLL-----EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQK 391
Cdd:COG4942     92 IAELRAELEAQKEELAEllRALYRLGRQPPLALLLspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1483569506  392 TGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLE------DQLQQKSKEISQFLNRLPLQQHETASQTS 458
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAelaaelAELQQEAEELEALIARLEAEAAAAAERTP 244
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1307-1465 1.15e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 1.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1307 TSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLktvsheaevhaESLQQKLESSQLQI 1386
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEV-----------EARIKKYEEQLGNV 85

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1483569506 1387 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1465
Cdd:COG1579     86 RNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
707-912 1.30e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.17  E-value: 1.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  707 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADnnssaFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEMNLAEAERQr 785
Cdd:COG3206    175 KALEFLEEQLPELRKELEEAEAALEEFRQKNG-----LVDLSEEAKLLLQQLSELeSQLAEARAELAEAEARLAALRAQ- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  786 rLDYESQTAHDNLLTEQIHSLSIEakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRH---- 861
Cdd:COG3206    249 -LGSGPDALPELLQSPVIQQLRAQ-------LAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAslea 320

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1483569506  862 ----ISSKVEELSQALSQKELEITKMDQL---LLEKKRDVETLQQTIEEKDQQVTEIS 912
Cdd:COG3206    321 eleaLQAREASLQAQLAQLEARLAELPELeaeLRRLEREVEVARELYESLLQRLEEAR 378
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2354-2909 1.68e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 1.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2354 IQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI--ISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQEEEENIV 2431
Cdd:PRK03918   171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLreINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELES 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2432 LEEENKKAVDKTNQLMETLKTIKKEniqqKAQLDSFVKSMSSLQNDRDRivgdYQQLEERHLSIILEKDQLIQEAAaenn 2511
Cdd:PRK03918   250 LEGSKRKLEEKIRELEERIEELKKE----IEELEEKVKELKELKEKAEE----YIKLSEFYEEYLDELREIEKRLS---- 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2512 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK----QLLEVQLQQNKELENKYAKL--EEKLKESE 2585
Cdd:PRK03918   318 RLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeeaKAKKEELERLKKRLTGLTPEklEKELEELE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2586 EANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT----------RQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSS 2655
Cdd:PRK03918   398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2656 SQKRIAELEEEL-----VCVQKEAAKKVGEIEDKLKK-----------ELKHLHHDAGIMRNETETAE---ERVAELARD 2716
Cdd:PRK03918   478 LRKELRELEKVLkkeseLIKLKELAEQLKELEEKLKKynleelekkaeEYEKLKEKLIKLKGEIKSLKkelEKLEELKKK 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2717 LVEMEQKLLMVTKENKGLTAQIQSFGRSmsslqnSRDHANEELDELKRKYDA--SLKELAQLKEQGLLNRERDALLSETA 2794
Cdd:PRK03918   558 LAELEKKLDELEEELAELLKELEELGFE------SVEELEERLKELEPFYNEylELKDAEKELEREEKELKKLEEELDKA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2795 FSMNSTEENSLSHLEKLNQQLLSKDEQLLHlssqlEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQP 2874
Cdd:PRK03918   632 FEELAETEKRLEELRKELEELEKKYSEEEY-----EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1483569506 2875 STSPAEVQSLKKAMSSLQNDRDRlLKELKNLQQQY 2909
Cdd:PRK03918   707 EKAKKELEKLEKALERVEELREK-VKKYKALLKER 740
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 998-1875 1.68e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  998 RKLQAALinrkELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE-NKEYSEKCVTSKCQEIEIYLKQ------T 1070
Cdd:TIGR02169  170 RKKEKAL----EELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQkeaierQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1071 ISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKT-NQIDLLQAEISENQAIIQKLITSNTDASDgdSVALVKET 1149
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGeEEQLRVKEKIGELEAEIASLERSIAEKER--ELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1150 VVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKE---RHLREELKQQKDDYNRLQEQFDE 1226
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDkefAETRDELKDYREKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1227 QSKENENIGDQLRQLQIQVREsIDGKLPSTDQQ--ESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQ 1304
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELAD-LNAAIAGIEAKinELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1305 GGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEE-----VFQLQEQINKQGLEIES-----LKTVSHEAEVHAES 1374
Cdd:TIGR02169  483 KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtVAQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1375 LQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKI---QTEIIEQEDLIKALHTQLEMQ 1451
Cdd:TIGR02169  563 AIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYvfgDTLVVEDIEAARRLMGKYRMV 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1452 AKEHDERIK---------QLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLT 1522
Cdd:TIGR02169  643 TLEGELFEKsgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1523 KSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRsllenqslssscesLKLALEGLTEDKEKLVKEIESLKSSK 1602
Cdd:TIGR02169  723 KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE--------------LEARIEELEEDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1603 IAEstEWQEKHKELQKEYEIlLQSYENVSNEAERI----QHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAeqemee 1678
Cdd:TIGR02169  789 SHS--RIPEIQAELSKLEEE-VSRIEARLREIEQKlnrlTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL------ 859

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1679 mkekmrkfakskQQKILELEEENDRLRAEVhpagdtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLS 1758
Cdd:TIGR02169  860 ------------NGKKEELEEELEELEAAL-----------RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1759 EEVQDLKHQIEGNVSKQANLEATEKHDnqtnvteegtQSIPGETEEQDSLSMsTRPTCSESVPSAKSANpavskdFSSHD 1838
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGED----------EEIPEEELSLEDVQA-ELQRVEEEIRALEPVN------MLAIQ 979

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 1483569506 1839 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEK 1875
Cdd:TIGR02169  980 EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1588-2916 1.80e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 50.82  E-value: 1.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1588 KEKLVKEIESLKSSKIAESTEWQEKHKELQKEYE-------ILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTeA 1660
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEeenedsiHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNI-S 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1661 NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRaevhpagdtakecmetllssnASMKEELERV-KME 1739
Cdd:TIGR01612  614 DKNEYIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIY---------------------STIKSELSKIyEDD 672

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1740 YETLSKKFQSLMSEKDSLSEE----VQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPT 1815
Cdd:TIGR01612  673 IDALYNELSSIVKENAIDNTEdkakLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKD 752

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1816 CSESVPSAKSANPAVSKDFSSH----DEINNYLQQIDQLKERIAG-LEEEKQKNKEFSQTLENEKNtLLSQISTKDGELK 1890
Cdd:TIGR01612  753 LNKILEDFKNKEKELSNKINDYakekDELNKYKSKISEIKNHYNDqINIDNIKDEDAKQNYDKSKE-YIKTISIKEDEIF 831

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1891 MLQEEVTKMNllnqqiQEELSRVTKLKETAEEEKDDLEERlMNQLAELNGSIGNycqdvtdaQIKNELLESEMKNLKKCV 1970
Cdd:TIGR01612  832 KIINEMKFMK------DDFLNKVDKFINFENNCKEKIDSE-HEQFAELTNKIKA--------EISDDKLNDYEKKFNDSK 896

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1971 SELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKE--LQELLKEKQQEVKQLQKDCIRYQ--------EKI 2040
Cdd:TIGR01612  897 SLINEINKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQniLKEILNKNIDTIKESNLIEKSYKdkfdntliDKI 976

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2041 SALERTVKALEFVQTESQKDLEIT-----KENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKL--KKELQSN 2113
Cdd:TIGR01612  977 NELDKAFKDASLNDYEAKNNELIKyfndlKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIaiHTSIYNI 1056

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2114 KESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeiqvtlnKKDKEVQQLQENLDSTVTQLA 2193
Cdd:TIGR01612 1057 IDEIEKEIGKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDFGKEENI--------KYADEINKIKDDIKNLDQKID 1128

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2194 AFTKSMSSLQDDRDRVIDEAK----KWERKFSDAIQSKE-EEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQI 2268
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKaqinDLEDVADKAISNDDpEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTS 1208

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2269 WESKAQTEVQLQQKVcdtlqgeNKELLSQLEEtrhlyhssqnELAKLESELKSLKDQLTDLSNSLEKCKEQKgNLEGIIR 2348
Cdd:TIGR01612 1209 LEEVKGINLSYGKNL-------GKLFLEKIDE----------EKKKSEHMIKAMEAYIEDLDEIKEKSPEIE-NEMGIEM 1270

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2349 QQEADIQNSKFSYEQLETDLQASRELTSRLhEEINMKEQKIISLLSGK------EEAIQVAIAElRQQHDKEIKELENLL 2422
Cdd:TIGR01612 1271 DIKAEMETFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEEsdindiKKELQKNLLD-AQKHNSDINLYLNEI 1348

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2423 SQEEEENIVLEEEN--KKAVDKTNQLMETLKTIKKEnIQQKAQLDSFVKSMSSLQNDRDRIVG--DYQQLEERHLSIILE 2498
Cdd:TIGR01612 1349 ANIYNILKLNKIKKiiDEVKEYTKEIEENNKNIKDE-LDKSEKLIKKIKDDINLEECKSKIEStlDDKDIDECIKKIKEL 1427

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2499 KDQLIQEAAAENNKLKEEirglrshmdDLNSENAKLDAELIQYREDLNQ-VITIKDSQQKQLLEV---QLQQNKELENKY 2574
Cdd:TIGR01612 1428 KNHILSEESNIDTYFKNA---------DENNENVLLLFKNIEMADNKSQhILKIKKDNATNDHDFninELKEHIDKSKGC 1498

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2575 AKLEEKLKESEEANEDLRRSFNalQEEKQDLSKEIE-SLKVSISQLTRQVTALQEEgtLGLYHAQLKVKEEevhrlsalf 2653
Cdd:TIGR01612 1499 KDEADKNAKAIEKNKELFEQYK--KDVTELLNKYSAlAIKNKFAKTKKDSEIIIKE--IKDAHKKFILEAE--------- 1565

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2654 sSSQKRIAELEEELVCVQKEAAK-------------KVGEIEDKLKKeLKHLHHDAGIMRNETETAEERVAELARDLVEM 2720
Cdd:TIGR01612 1566 -KSEQKIKEIKKEKFRIEDDAAKndksnkaaidiqlSLENFENKFLK-ISDIKKKINDCLKETESIEKKISSFSIDSQDT 1643

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2721 EqkllmvTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDEL--------------KRKYDASLKElaQLKEQGLLNRER 2786
Cdd:TIGR01612 1644 E------LKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELdseiekieidvdqhKKNYEIGIIE--KIKEIAIANKEE 1715

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2787 dalLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMAS--------------LQNERDH 2852
Cdd:TIGR01612 1716 ---IESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGcletvskepitydeIKNTRIN 1792

                         1370      1380      1390      1400      1410      1420
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 2853 LWNELEKFRKSEegKQRSAAQPSTSPAEVQSLKKAM-SSLQNDRDRLLKELKNLQQQYLQINQEI 2916
Cdd:TIGR01612 1793 AQNEFLKIIEIE--KKSKSYLDDIEAKEFDRIINHFkKKLDHVNDKFTKEYSKINEGFDDISKSI 1855
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1581-2187 1.92e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 1.92e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1581 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEIL---LQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1657
Cdd:TIGR04523   98 INKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIdkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNL 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1658 TEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQ------KILELEEENDRLRAEVHPAGD----------TAKECMET 1721
Cdd:TIGR04523  178 LEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKnkslesQISELKKQNNQLKDNIEKKQQeinektteisNTQTQLNQ 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1722 LLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGE 1801
Cdd:TIGR04523  258 LKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKII 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1802 TEEQDSLSmstrptcsesvpsaksanpAVSKDFSSHDEINNYLQ-QIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1880
Cdd:TIGR04523  338 SQLNEQIS-------------------QLKKELTNSESENSEKQrELEEKQNEIEKLKKENQSYKQEIKNLESQINDLES 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1881 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEerlmNQLAELNGSIGNYCQDVTDAQIKNELLE 1960
Cdd:TIGR04523  399 KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT----NQDSVKELIIKNLDNTRESLETQLKVLS 474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1961 SEMKNLKkcvSELEEEKQQLVKEktkvESEIRKEYLEKIQGAQKepgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKI 2040
Cdd:TIGR04523  475 RSINKIK---QNLEQKQKELKSK----EKELKKLNEEKKELEEK-------VKDLTKKISSLKEKIEKLESEKKEKESKI 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2041 SALERTVKALEFvqtesqkdlEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQ 2120
Cdd:TIGR04523  541 SDLEDELNKDDF---------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK 611

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506 2121 MKQKDEDLErRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDS 2187
Cdd:TIGR04523  612 ISSLEKELE-KAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1836-2538 1.95e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.61  E-value: 1.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1836 SHDEINNYLQQIDQlkerIAGLEEEKQKnkefSQTLENEKNTLLSQIStkdgELKMLQEEVTKMNLlnqQIQEELSRVTK 1915
Cdd:pfam12128  219 NRQQVEHWIRDIQA----IAGIMKIRPE----FTKLQQEFNTLESAEL----RLSHLHFGYKSDET---LIASRQEERQE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1916 LKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcvSELEEEKQQLVKEKTkVESEIrkEY 1995
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLPS-WQSEL--EN 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1996 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQL----QKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2071
Cdd:pfam12128  359 LEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIagikDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2072 VEHRKKAQAELasfKVLLDDTQSEaarvladnlklkKELQSNKESVKSQMKQKDEDLERR---LEQAEEKHLKEKKNMQE 2148
Cdd:pfam12128  439 EYRLKSRLGEL---KLRLNQATAT------------PELLLQLENFDERIERAREEQEAAnaeVERLQSELRQARKRRDQ 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2149 KLDALRREKVHLEETIGEIqvtlnkkdkevQQLQENLDSTVTQLAAFTKSMSSL-QDDRDRVIDEAKKWErkfSDAIQSK 2227
Cdd:pfam12128  504 ASEALRQASRRLEERQSAL-----------DELELQLFPQAGTLLHFLRKEAPDwEQSIGKVISPELLHR---TDLDPEV 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2228 EEEIRLKEDNCSVLKDQLRQMSI-----HMEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETR 2302
Cdd:pfam12128  570 WDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKAEEALQ----SAREKQAAAEEQLVQANGELEKASREETFAR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2303 HLYHSSQNELAKLESELKSLKDQLTD-LSNSLEKCKEQKGNLEGIIRQQEADIQNSkfsyeqletdLQASRELTSRLHEE 2381
Cdd:pfam12128  646 TALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSLEAQLKQLDKKHQAW----------LEEQKEQKREARTE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2382 INMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKeNIQQK 2461
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAV-RRQEV 794

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506 2462 AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKdqLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAEL 2538
Cdd:pfam12128  795 LRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLAR--LIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM 869
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1169-1398 2.74e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1169 EKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1248
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAEL----EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE- 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1249 idgklpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTS------VAQIKAQLKEIEAE 1322
Cdd:COG4942     95 ---------LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAparreqAEELRADLAELAAL 165

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1483569506 1323 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPK 1398
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
46 PHA02562
endonuclease subunit; Provisional
 1838-1998 2.98e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 49.63  E-value: 2.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1838 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLK 1917
Cdd:PHA02562   227 EEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCT-QQISEGPDRITKIK 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1918 E---------TAEEEKDDLEERLMNQLA-------ELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLV 1981
Cdd:PHA02562   306 DklkelqhslEKLDTAIDELEEIMDEFNeqskkllELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQ 385

                          170
                   ....*....|....*..
gi 1483569506 1982 KEKTKVESEIRKEYLEK 1998
Cdd:PHA02562   386 DELDKIVKTKSELVKEK 402
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2243-2859 3.93e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 3.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2243 DQLRQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHlyHSSQNELAKLESELK 2320
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2321 SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ-EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEA 2399
Cdd:COG4913    313 RLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF--------AA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2400 IQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLdsfvksMSSLQNDRD 2479
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDAL------AEALGLDEA 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2480 --RIVGDYQQLEERH---------------LSIILEKDQLIQEAAA-ENNKLKEEIRGLRSHMDDLNSENAKLDAEliqy 2541
Cdd:COG4913    459 elPFVGELIEVRPEEerwrgaiervlggfaLTLLVPPEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDPD---- 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2542 reDLNQVITIKDSQQKQLLEVQLQqnkelenkyakleeklkeseeanedlrRSFNALQEEkqdlskeieslkvSISQLTR 2621
Cdd:COG4913    535 --SLAGKLDFKPHPFRAWLEAELG---------------------------RRFDYVCVD-------------SPEELRR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2622 QVTALQEEGTL-GLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKkVGEIEDKLKKELKHLH--HDAGI 2698
Cdd:COG4913    573 HPRAITRAGQVkGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAE-AEERLEALEAELDALQerREALQ 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2699 MRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAqiqsfgrsmssLQNSRDHANEELDELKRKYDASLKELAQL-K 2777
Cdd:COG4913    652 RLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA-----------LEEQLEELEAELEELEEELDELKGEIGRLeK 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2778 EQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLsKDEQLLHLSSQLEDSYnqvqsfskamASLQNERDHLWNEL 2857
Cdd:COG4913    721 ELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL-GDAVERELRENLEERI----------DALRARLNRAEEEL 789


                   ..
gi 1483569506 2858 EK 2859
Cdd:COG4913    790 ER 791
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1313-1521 4.32e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 4.32e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1313 KAQLKEIEAEKVELELKVSsttsELTKKSEEVFQLQEQINKQGLEIESLKTVShEAEVHAESLQQKLESSQLQiagLEHL 1392
Cdd:COG4913    609 RAKLAALEAELAELEEELA----EAEERLEALEAELDALQERREALQRLAEYS-WDEIDVASAEREIAELEAE---LERL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1393 RELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEmKQK 1472
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----AAEDLARLELRALLE-ERF 755

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1483569506 1473 PEEIGEESRakQQIQRKLQAALisrkealkenKSLQEELSLARGTIERL 1521
Cdd:COG4913    756 AAALGDAVE--RELRENLEERI----------DALRARLNRAEEELERA 792
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1389-2031 4.75e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.29  E-value: 4.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1389 LEHLRELQPKLDELQKLISKKEEdvsyLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDerikqlqvELCE 1468
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK--------ELEE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1469 MKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKsladVESQVSAQNKEKDTVLGRLAL 1548
Cdd:PRK03918   236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKE----KAEEYIKLSEFYEEYLDELRE 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1549 LQEERDKLitemDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKsskiaESTEWQEKHKELQKEYEILLQSYE 1628
Cdd:PRK03918   312 IEKRLSRL----EEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELE-----ERHELYEEAKAKKEELERLKKRLT 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1629 NvsNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQlqeaeqemeemkekmrkfAKSKQQKILELEEendrlraev 1708
Cdd:PRK03918   383 G--LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKE------------------IKELKKAIEELKK--------- 433

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1709 hpAGDTAKECMETLlssnasMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQT 1788
Cdd:PRK03918   434 --AKGKCPVCGREL------TEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQL 505

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1789 NVTEEGTQSIPGETEEQDslsmstrptcSESVPSAKSANPAVSKDFSShdeINNYLQQIDQLKERIAGLEEEKQKNKEFS 1868
Cdd:PRK03918   506 KELEEKLKKYNLEELEKK----------AEEYEKLKEKLIKLKGEIKS---LKKELEKLEELKKKLAELEKKLDELEEEL 572

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1869 QTLENEKNTL----LSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGN 1944
Cdd:PRK03918   573 AELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAE-TEKRLEELRKELEE 651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1945 YCQDVTDAQIKNelLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR--KEYLEKIQGAQKEPGNKSHAKELQELLKEK 2022
Cdd:PRK03918   652 LEKKYSEEEYEE--LREEYLELSRELAGLRAELEELEKRREEIKKTLEklKEELEEREKAKKELEKLEKALERVEELREK 729


                   ....*....
gi 1483569506 2023 QQEVKQLQK 2031
Cdd:PRK03918   730 VKKYKALLK 738
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1836-2353 4.78e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.35  E-value: 4.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1836 SHDEINNYLQQ-IDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQistkdgeLKMLQEEVTKMN-LLNQQIQEELSRV 1913
Cdd:pfam15921  254 SQNKIELLLQQhQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQ-------LEIIQEQARNQNsMYMRQLSDLESTV 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1914 TKLKETAEEEKDDLEERLmnqlAELNGSIGNYCQDVTDAQIKNELLESEMKNLkkcvselEEEKQQLVKEKTKVESEIRK 1993
Cdd:pfam15921  327 SQLRSELREAKRMYEDKI----EELEKQLVLANSELTEARTERDQFSQESGNL-------DDQLQKLLADLHKREKELSL 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1994 EYLEKIQGAQKEPGNKSHAKELQELLKEKQQEV-------KQLQKDCI-RYQEKISALERTVKALEFVQTESQKdLEITK 2065
Cdd:pfam15921  396 EKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVqrleallKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQ-LESTK 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2066 ENLAQAVEHRKKAQAELASFKVLLDD--------------TQSEAARVLAD-NLKLK------------KELQSNKESVK 2118
Cdd:pfam15921  475 EMLRKVVEELTAKKMTLESSERTVSDltaslqekeraieaTNAEITKLRSRvDLKLQelqhlknegdhlRNVQTECEALK 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2119 SQMKQKDEDLERrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK----KDKEVQQLQEnLDSTVTQLAA 2194
Cdd:pfam15921  555 LQMAEKDKVIEI-LRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilKDKKDAKIRE-LEARVSDLEL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2195 FTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHME--------ELKINISRLEHDK 2266
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEtttnklkmQLKSAQSELEQTR 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2267 QIWESKA-------------QTEVQLQQKVCDTLQGENK---ELLSQLEETRHLYHSSQNELAK---------------- 2314
Cdd:pfam15921  713 NTLKSMEgsdghamkvamgmQKQITAKRGQIDALQSKIQfleEAMTNANKEKHFLKEEKNKLSQelstvateknkmagel 792

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1483569506 2315 --LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEAD 2353
Cdd:pfam15921  793 evLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 157-446 5.26e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.18  E-value: 5.26e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  157 EELISTLQAQLTQAQAEQPAQSSTEMEefvmMKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREK-DARFETQ- 234
Cdd:COG3096    835 EAELAALRQRRSELERELAQHRAQEQQ----LRQQLDQLKEQLQLLNKLLPQANLLADETLADRLEELREElDAAQEAQa 910

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  235 -VRLHEDELLQLVTQADVetemqqklrvLQRKLEEHEEslvgraqvvdlLQQELTAAEQRNQILSQQLQQME-----AEH 308
Cdd:COG3096    911 fIQQHGKALAQLEPLVAV----------LQSDPEQFEQ-----------LQADYLQAKEQQRRLKQQIFALSevvqrRPH 969

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  309 NTLRNTVETeREESKILLEKME--LEVAERKLSfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKtshi 386
Cdd:COG3096    970 FSYEDAVGL-LGENSDLNEKLRarLEQAEEARR--EAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQEL---- 1042

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1483569506  387 lslqktgQELQSACDALKDQNSKLLQDK-NEQAVQSAQTIQQLEDQLQQKSKEISQFLNRL 446
Cdd:COG3096   1043 -------EELGVQADAEAEERARIRRDElHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRL 1096
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1829-2067 5.66e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 5.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1829 AVSKDFSSHDEINNYLQQIDQLKERIAgleeEKQKNKEFSQTLENEKNTLLSQISTKDGELkmlqeEVTKMNLLNQQIQE 1908
Cdd:NF012221  1536 ATSESSQQADAVSKHAKQDDAAQNALA----DKERAEADRQRLEQEKQQQLAAISGSQSQL-----ESTDQNALETNGQA 1606

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1909 ELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGN-YCQDVTDAQIKNelLESEMKNLKKCVSE-LEEEKQQLVKEK 1984
Cdd:NF012221  1607 QRDAILEESRAVTKELTTLAQGLdaLDSQATYAGESGDqWRNPFAGGLLDR--VQEQLDDAKKISGKqLADAKQRHVDNQ 1684

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1985 TKVESEIRKEYLEKIQGAQKEPG-------NKSHAKELQELLKEKQQEVKQLQKDC-IRYQEKISALERTVKALEFVQTE 2056
Cdd:NF012221  1685 QKVKDAVAKSEAGVAQGEQNQANaeqdiddAKADAEKRKDDALAKQNEAQQAESDAnAAANDAQSRGEQDASAAENKANQ 1764

                          250
                   ....*....|.
gi 1483569506 2057 SQKDLEITKEN 2067
Cdd:NF012221  1765 AQADAKGAKQD 1775
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 924-1642 5.93e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 5.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  924 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEfDLLKKENEQRKRKLQAA 1003
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK-REAQEEQLKKQQLLKQL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1004 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRK 1083
Cdd:TIGR00618  266 RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRR 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1084 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHW 1163
Cdd:TIGR00618  346 LLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1164 KPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDdynrlQEQFDEQSKENENIGDQLRQLQI 1243
Cdd:TIGR00618  426 LAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-----KEQIHLQETRKKAVVLARLLELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1244 QVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNlcpdwpshSEDASALQGGTSVAQIKAQLKEIEAEK 1323
Cdd:TIGR00618  501 EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE--------DVYHQLTSERKQRASLKEQMQEIQQSF 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1324 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE----------SLQQKLESSQLQIAGLEHLR 1393
Cdd:TIGR00618  573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdlqdvrlHLQQCSQELALKLTALHALQ 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1394 ELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDL--IKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1471
Cdd:TIGR00618  653 LTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLaqCQTLLRELETHIEEYDREFNEIENASSSLGS 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1472 kpeEIGEESRAKQQIQRKLQAaliSRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1551
Cdd:TIGR00618  733 ---DLAAREDALNQSLKELMH---QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1552 ERDklitemdrsllenqslssscESLKLALEGLTEDKEKLVKEIESLKsSKIAESTEWQEKHKELQKEYEILLQSYENVS 1631
Cdd:TIGR00618  807 EIG--------------------QEIPSDEDILNLQCETLVQEEEQFL-SRLEEKSATLGEITHQLLKYEECSKQLAQLT 865

                          730
                   ....*....|.
gi 1483569506 1632 NEAERIQHVVE 1642
Cdd:TIGR00618  866 QEQAKIIQLSD 876
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1771-2187 6.38e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 49.13  E-value: 6.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1771 NVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTC-SESVPSAKSANPAVSKDFSSHDEINNYLQQIDQ 1849
Cdd:PLN02939    41 GFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELpQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1850 LKERIAGLEEEkqknkEFSQTLEN-EKNTLLsqistkdgelkmlqeevtkMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1928
Cdd:PLN02939   121 DGEQLSDFQLE-----DLVGMIQNaEKNILL-------------------LNQARLQALEDLEKILTEKEALQGKINILE 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1929 ERLMNQLAELNGSignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEkiqgaqkepgn 2008
Cdd:PLN02939   177 MRLSETDARIKLA--------AQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENML----------- 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2009 kshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL----EITKENLAQAVEhrkkaqaelaS 2084
Cdd:PLN02939   238 ---LKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVsklsPLQYDCWWEKVE----------N 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2085 FKVLLDDTQSE---AARVLADNLKLKKELQSNKESVKSQMKQKD-----EDLERRLEQAEEKHLKEKKNMQEKLDAlrre 2156
Cdd:PLN02939   305 LQDLLDRATNQvekAALVLDQNQDLRDKVDKLEASLKEANVSKFssykvELLQQKLKLLEERLQASDHEIHSYIQL---- 380

                          410       420       430
                   ....*....|....*....|....*....|...
gi 1483569506 2157 kvhLEETIGEIQVTLNK--KDKEVQQLQENLDS 2187
Cdd:PLN02939   381 ---YQESIKEFQDTLSKlkEESKKRSLEHPADD 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2012-2230 7.00e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 7.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2012 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDD 2091
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2092 TQSEAARVLADNLKLkkelqSNKESVKSQMKQKD-EDLERR---LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEI 2167
Cdd:COG4942    102 QKEELAELLRALYRL-----GRQPPLALLLSPEDfLDAVRRlqyLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1483569506 2168 QVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2230
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 832-1074 7.28e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 48.39  E-value: 7.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  832 SEQSTLIRSLQSQ--LQNKESEVLEGAERVRHISSKVEELSQALSQ----KELEITKMDQLLLEKKRDVETLQQTIEEKD 905
Cdd:PRK05771    16 SYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDKlrsyLPKLNPLREEKKKVSVKSLEELIKDVEEEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  906 QQVTEISFSMTEKMVQLNEEKFSL-------------GVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSG-----LKQN 967
Cdd:PRK05771    96 EKIEKEIKELEEEISELENEIKELeqeierlepwgnfDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVenveyISTD 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  968 YDEMSPAGQISKEELQHEFDLLKKENEQRKRklqaaLINRKELLQRVSRLEEELANLKDeskkeiplsetERGEVEED-- 1045
Cdd:PRK05771   176 KGYVYVVVVVLKELSDEVEEELKKLGFERLE-----LEEEGTPSELIREIKEELEEIEK-----------ERESLLEElk 239

                          250       260       270
                   ....*....|....*....|....*....|....*
gi 1483569506 1046 KENKEYSEKCVTSKC------QEIEIYLKQTISEK 1074
Cdd:PRK05771   240 ELAKKYLEELLALYEyleielERAEALSKFLKTDK 274
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 188-1053 7.87e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.81  E-value: 7.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  188 MKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVEtEMQQKLRVLQRKLE 267
Cdd:pfam02463  190 IDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIE-SSKQEIEKEEEKLA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  268 EHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNtvetEREESKILLEKMELEVAERKLSFHNLQEEM 347
Cdd:pfam02463  269 QVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEE----KLKESEKEKKKAEKELKKEKEEIEELEKEL 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  348 HHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQEL-QSACDALKDQNSKLLQDKNEQAVQSAQTIQ 426
Cdd:pfam02463  345 KELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKeEELELKSEEEKEAQLLLELARQLEDLLKEE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  427 QLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPdvYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAEN 506
Cdd:pfam02463  425 KKEELEILEEEEESIELKQGKLTEEKEELEKQEL--KLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKE 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  507 EKLSSQITLLEAQNRTGEADRevseISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQ 586
Cdd:pfam02463  503 SKARSGLKVLLALIKDGVGGR----IISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGAR 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  587 GKRAEEADHEVLDQKEMKqmegEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVEL 666
Cdd:pfam02463  579 KLRLLIPKLKLPLKSIAV----LEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  667 KSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLiEEFKKNADNNSSAFTA 746
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKL-EAEELLADRVQEAQDK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  747 LSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHS--------LSIEAKSKDVKIE 818
Cdd:pfam02463  734 INEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKeeklkaqeEELRALEEELKEE 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  819 VLQNELDDV---------QLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLE 889
Cdd:pfam02463  814 AELLEEEQLlieqeekikEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE 893

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  890 KKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQN-- 967
Cdd:pfam02463  894 KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEElg 973

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  968 YDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE 1047
Cdd:pfam02463  974 KVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLELGGSAELRLEDP 1053


                   ....*.
gi 1483569506 1048 NKEYSE 1053
Cdd:pfam02463 1054 DDPFSG 1059
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2306-2543 8.47e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 8.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2306 HSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMK 2385
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2386 EQKIISLlsgKEEAIQVAIAELRQQHDKEIKELenLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLD 2465
Cdd:COG4942     96 RAELEAQ---KEELAELLRALYRLGRQPPLALL--LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1483569506 2466 SFVKSMSSLQNDRdrivgdyQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYRE 2543
Cdd:COG4942    171 AERAELEALLAEL-------EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1853-2389 1.19e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.15  E-value: 1.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1853 RIAGLEEEKQKNKEFSQT-LENEKNTLLSQIS-TKDGELKMLQEEVTKMNLLNQQIQ-EELSRVTKLKETAE----EEKD 1925
Cdd:COG5022    870 YLQSAQRVELAERQLQELkIDVKSISSLKLVNlELESEIIELKKSLSSDLIENLEFKtELIARLKKLLNNIDleegPSIE 949

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1926 DLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLE-------SEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK--EYL 1996
Cdd:COG5022    950 YVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVregnkanSELKNFKKELAELSKQYGALQESTKQLKELPVEvaELQ 1029

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1997 EKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT-KENLAQAVEHR 2075
Cdd:COG5022   1030 SASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINvKDLEVTNRNLV 1109

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2076 KKAQAE----LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDeDLERRLEQAEEKHLKEKKNMQEK-L 2150
Cdd:COG5022   1110 KPANVLqfivAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEA-NLEALPSPPPFAALSEKRLYQSAlY 1188

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2151 DALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQ---SK 2227
Cdd:COG5022   1189 DEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSllnSI 1268

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2228 EEEIRLKEDNCSVLKDQLRQMSIHMEELKINisRLEHDKQIWESKAQTEVQLQQKVCDT--LQGENKEL---LSQLEETR 2302
Cdd:COG5022   1269 DNLLSSYKLEEEVLPATINSLLQYINVGLFN--ALRTKASSLRWKSATEVNYNSEELDDwcREFEISDVdeeLEELIQAV 1346

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2303 HLYHSSQNELAKLESELKSLKDQLTDLSNSLeKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEI 2382
Cdd:COG5022   1347 KVLQLLKDDLNKLDELLDACYSLNPAEIQNL-KSRYDPADKENNLPKEILKKIEALLIKQELQLSLEGKDETEVHLSEIF 1425


                   ....*..
gi 1483569506 2383 NMKEQKI 2389
Cdd:COG5022   1426 SEEKSLI 1432
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 716-910 1.25e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  716 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELS-MVTELRAQVKQLEMNLAEAERQRRLDYESQTA 794
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALArRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  795 HDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 874
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1483569506  875 QKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTE 910
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2601-3189 1.26e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 1.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2601 EKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGE 2680
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELT---------AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2681 IEdKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELD 2760
Cdd:TIGR02168  304 KQ-ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2761 ELKRKYdaslkelAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDsynqvqsfs 2840
Cdd:TIGR02168  383 TLRSKV-------AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELE--------- 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2841 KAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH 2920
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2921 PLKAQLQEYQ-----------------DKTKAFQImQEELRQENLSWQH--ELHQLRMEKSSWEIHERRMK-EQYLMAIS 2980
Cdd:TIGR02168  527 ELISVDEGYEaaieaalggrlqavvveNLNAAKKA-IAFLKQNELGRVTflPLDSIKGTEIQGNDREILKNiEGFLGVAK 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2981 DKDQQLSHLQNLIRELRSSSS------QTQPLKVQYQRQASPET----SASPDGSQN----------LVYETEL--LRTQ 3038
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLvvddldNALELAKKLRPGYRIVTldgdLVRPGGVITggsaktnssiLERRREIeeLEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 3039 LNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDV---A 3115
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAeieE 765

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 3116 PGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERD---------------------QRVAAEN 3174
Cdd:TIGR02168  766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlrerleslerriaaterRLEDLEE 845

                          650
                   ....*....|....*
gi 1483569506 3175 ALSVAEEQIRRLEHS 3189
Cdd:TIGR02168  846 QIEELSEDIESLAAE 860
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
679-1130 1.27e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 1.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  679 AVPDIGQCHQDELERLKSQILELE-LNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLlsq 757
Cdd:PRK02224   177 GVERVLSDQRGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL--- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  758 vkelsmvTELRAQVKQLEMNLAEAERQRR-LDYESQTAHDNLLT--EQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQ 834
Cdd:PRK02224   254 -------ETLEAEIEDLRETIAETEREREeLAEEVRDLRERLEEleEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  835 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV------ 908
Cdd:PRK02224   327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFgdapvd 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  909 ----TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK----EQVEEDNEVSSGLKQNYDEmspagqisKE 980
Cdd:PRK02224   407 lgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVETIEEDRER--------VE 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  981 ELQHEFDLLKKENEQRKRKLQAAlINRKELLQRVSRLEEELANLKDeskkeipLSETERGEVEEDKEnkeysekcvtsKC 1060
Cdd:PRK02224   479 ELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEE-------LIAERRETIEEKRE-----------RA 539

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1483569506 1061 QEieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLL------QAEISENQAIIQKL 1130
Cdd:PRK02224   540 EE----LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLerirtlLAAIADAEDEIERL 611
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2290-2510 1.28e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2290 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ 2369
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2370 ASRE-LTSRLHEEINMKEQKIISLLSGKEEAIQVA-----IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2443
Cdd:COG4942    101 AQKEeLAELLRALYRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506 2444 NQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAEN 2510
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1945-2682 1.30e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1945 YCQDVTDAQIK----NELLESEMKNLKKCVSELEEEKQQLVKEKTKVeSEIRKEYLEKIQGAQKEPGNKSH----AKELQ 2016
Cdd:pfam15921   83 YSHQVKDLQRRlnesNELHEKQKFYLRQSVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHeleaAKCLK 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2017 E-LLKEKQQEVKQLQKDCIRYQEKISALERTVkaLEFVQTESQKdleITKENLAQAVEHRKKAQAelasFKVLLDDTQSE 2095
Cdd:pfam15921  162 EdMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL--VDFEEASGKK---IYEHDSMSTMHFRSLGSA----ISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2096 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2175
Cdd:pfam15921  233 ISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2176 KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDeaKKWERKFSDAIQSKEEEIRLKEDNCSvLKDQLRQM--SIHME 2253
Cdd:pfam15921  313 SMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELE--KQLVLANSELTEARTERDQFSQESGN-LDDQLQKLlaDLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2254 ELKINISRlEHDKQIWESKAQTEVQLQ-------------QKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELK 2320
Cdd:pfam15921  390 EKELSLEK-EQNKRLWDRDTGNSITIDhlrrelddrnmevQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2321 SLKDQLTDLSNSLEKCKEQKGNLEgiirQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKE--- 2397
Cdd:pfam15921  469 QLESTKEMLRKVVEELTAKKMTLE----SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDhlr 544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2398 ------EAIQVAIAE-------LRQQhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL 2464
Cdd:pfam15921  545 nvqtecEALKLQMAEkdkvieiLRQQ----IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKI 620

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2465 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQE---AAAENNKLKEEI----RGLRSHMDDLNSENAKLDAE 2537
Cdd:pfam15921  621 RELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTTNKLKMQ 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2538 LIQYREDLNQVITIKDSQQK---QLLEVQLQQNKELENKYAKLEEKLKESEEANEDL---RRSFNALQEEKQDLSKEIES 2611
Cdd:pfam15921  701 LKSAQSELEQTRNTLKSMEGsdgHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMtnaNKEKHFLKEEKNKLSQELST 780

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 2612 LKVSISQLTRQVTALQEEgtlglyHAQLKVK----EEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIE 2682
Cdd:pfam15921  781 VATEKNKMAGELEVLRSQ------ERRLKEKvanmEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
705-957 1.65e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  705 FHKAQeiyeknldeKAKEISNLNQLIEEF-------KKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMN 777
Cdd:COG4913    197 LHKTQ---------SFKPIGDLDDFVREYmleepdtFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  778 LAEAERQRRLD-----YESQTAHDnLLTEQIHSLSIEakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV 852
Cdd:COG4913    268 RERLAELEYLRaalrlWFAQRRLE-LLEAELEELRAE-------LARLEAELERLEARLDALREELDELEAQIRGNGGDR 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  853 LEGAER--------VRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNE 924
Cdd:COG4913    340 LEQLEReierlereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRR 419

                          250       260       270
                   ....*....|....*....|....*....|...
gi 1483569506  925 EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEED 957
Cdd:COG4913    420 ELRELEAEIASLERRKSNIPARLLALRDALAEA 452
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1992-2185 1.99e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1992 RKEYLEKIQGaQKEPGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERTVKALEFVQTESQKDLEITK--ENLA 2069
Cdd:COG4717     54 EADELFKPQG-RKPELNLKELKELEEELKEAEEKEEEYAEL----QEELEELEEELEELEAELEELREELEKLEklLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2070 QAVEHRKKAQAELASFKVLLDDTQSEAARVladnlklkKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2149
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1483569506 2150 LDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2185
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENEL 236
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
687-1050 2.31e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  687 HQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVT 765
Cdd:PRK02224   354 LEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELrEREA 429

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  766 ELRAQVKQLEMNLAEAERQRRLDYESQTAHDnlLTEQIHSLSIEakSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSqL 845
Cdd:PRK02224   430 ELEATLRTARERVEEAEALLEAGKCPECGQP--VEGSPHVETIE--EDRERVEELEAELEDLEEEVEEVEERLERAED-L 504

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  846 QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDqlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEE 925
Cdd:PRK02224   505 VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELR----ERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK 580

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  926 KFSLGVEIKTLKEQLNLLSRAEEAKkEQVEEDNEVSSGLKQNYDEmspagqiSKEELQHEFD----LLKKENEQRKRKLQ 1001
Cdd:PRK02224   581 LAELKERIESLERIRTLLAAIADAE-DEIERLREKREALAELNDE-------RRERLAEKRErkreLEAEFDEARIEEAR 652

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1483569506 1002 AALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1050
Cdd:PRK02224   653 EDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERRE 701
PTZ00121 PTZ00121
MAEBL; Provisional
 704-1248 2.36e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.44  E-value: 2.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  704 NFHKAQEIYEKNLDEKAKEISNlnqlIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMV---TELRAQVKQLEMNLAE 780
Cdd:PTZ00121  1210 EERKAEEARKAEDAKKAEAVKK----AEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFArrqAAIKAEEARKADELKK 1285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  781 AERQRRLDyESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAE 857
Cdd:PTZ00121  1286 AEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  858 RvrhisSKVEELSQALSQKELEITKMDQlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlneekfslgvEIKTLK 937
Cdd:PTZ00121  1365 K-----AEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAKK------------KADEAK 1424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  938 EQLNLLSRAEEAKKEQveEDNEVSSGLKQNYDEMSPAGQISKE-ELQHEFDLLKKENEQRKRKLQAalinrKELLQRVSR 1016
Cdd:PTZ00121  1425 KKAEEKKKADEAKKKA--EEAKKADEAKKKAEEAKKAEEAKKKaEEAKKADEAKKKAEEAKKADEA-----KKKAEEAKK 1497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1017 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQfq 1096
Cdd:PTZ00121  1498 KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED-- 1575

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1097 alvKQMNQTLQDKTNQIDllQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISppctGSSEHWKPELEEKILALEK 1176
Cdd:PTZ00121  1576 ---KNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK----AEEEKKKVEQLKKKEAEEK 1646

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1483569506 1177 EKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1248
Cdd:PTZ00121  1647 KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
152-330 2.39e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.93  E-value: 2.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  152 KLQEKEELISTLQAQLTQAQAEQpAQSSTEMEEF------VMMKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVR 225
Cdd:COG3206    169 RREEARKALEFLEEQLPELRKEL-EEAEAALEEFrqknglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  226 EKDARFETQVRLHEDELLQLVTQ--ADVETEMQQ----------KLRVLQRKLEEHEESLVGRAQ-VVDLLQQELTAAEQ 292
Cdd:COG3206    248 QLGSGPDALPELLQSPVIQQLRAqlAELEAELAElsarytpnhpDVIALRAQIAALRAQLQQEAQrILASLEAELEALQA 327

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1483569506  293 RNQILSQQLQQM----------EAEHNTLRNTVETEREESKILLEKME 330
Cdd:COG3206    328 REASLQAQLAQLearlaelpelEAELRRLEREVEVARELYESLLQRLE 375
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1473-1712 2.40e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1473 PEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEE 1552
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1553 RDKLITEMDRSLLENQSLSSScESLKLALEGltEDKEKLVKEIESLKSSkiaestewQEKHKELQKEYEILLQSYENVSN 1632
Cdd:COG4942     99 LEAQKEELAELLRALYRLGRQ-PPLALLLSP--EDFLDAVRRLQYLKYL--------APARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1633 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAG 1712
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1849-2180 2.65e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.66  E-value: 2.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1849 QLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQIST-KDGELKMLQEEVTKMNLLNQQIQEELSRVTKlketaEEEKDDL 1927
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKaRQAEMDRQAAIYAEQERMAMERERELERIRQ-----EERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1928 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepg 2007
Cdd:pfam17380  363 ERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRAEQEEARQ------- 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2008 nkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALErtvkalefvqtesQKDLEITKENLAQAVEHRKKAQAELASFKV 2087
Cdd:pfam17380  435 -----REVRRLEEERAREMERVRLEEQERQQQVERLR-------------QQEEERKRKKLELEKEKRDRKRAEEQRRKI 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2088 LLDDTQSEAARVLADNLK---LKKELQSNKESVKSQMKQKDEDLERRleqaEEKHLKEKKNMQEKLDALRREKVHLEETI 2164
Cdd:pfam17380  497 LEKELEERKQAMIEEERKrklLEKEMEERQKAIYEEERRREAEEERR----KQQEMEERRRIQEQMRKATEERSRLEAME 572

                          330
                   ....*....|....*.
gi 1483569506 2165 GEIQVTLNKKDKEVQQ 2180
Cdd:pfam17380  573 REREMMRQIVESEKAR 588
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2896-3186 2.88e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.97  E-value: 2.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2896 DRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKE-- 2973
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRErl 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2974 -----QYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdgsqnlvyETELLRTQLNDSLKEIHQ 3048
Cdd:TIGR02168  312 anlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA---------------ELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 3049 KELRIQQLNSNFSQLLEEKNTLSIQLcdtsQSLRENQQHygdllnhcavLEKQVQELQagplnidvapgapQEKNGVHRK 3128
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEI----ERLEARLER----------LEDRRERLQ-------------QEIEELLKK 429

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1483569506 3129 SDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRL 3186
Cdd:TIGR02168  430 LEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
PLN02939 PLN02939
transferase, transferring glycosyl groups
 631-998 3.07e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 3.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  631 PNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDeleRLKSQILELelNFHKAQE 710
Cdd:PLN02939    40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHN---RASMQRDEA--IAAIDNE 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  711 IYEKNLDEKakEISNLNqlIEEFKKNADNNSSAFTALSEERDQLLSQV-KELSMVTELRAQVKQLEMNLAEAERQRRLDY 789
Cdd:PLN02939   115 QQTNSKDGE--QLSDFQ--LEDLVGMIQNAEKNILLLNQARLQALEDLeKILTEKEALQGKINILEMRLSETDARIKLAA 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  790 ESQtAHDNLLTEQI----HSLSIEAKSKDVKIEVLQNELDDVQlqfsEQSTLIRSLQSQLQNKESEVLEGAERV------ 859
Cdd:PLN02939   191 QEK-IHVEILEEQLeklrNELLIRGATEGLCVHSLSKELDVLK----EENMLLKDDIQFLKAELIEVAETEERVfkleke 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  860 -RHISSKVEELSQALSQKELEITKMDQLLLEKKRD-VETLQQTIEEKDQQVTEISFSMT-----EKMVQLNEEKFSLGVE 932
Cdd:PLN02939   266 rSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEkVENLQDLLDRATNQVEKAALVLDqnqdlRDKVDKLEASLKEANV 345

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1483569506  933 IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiSKEELQHEFDLLKKENEQRKR 998
Cdd:PLN02939   346 SKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQE-------SIKEFQDTLSKLKEESKKRSL 404
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 282-519 3.89e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  282 LLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEkmELEVAERKLSfhNLQEEMHHLLEQFEQAGQAQ 361
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLK--QLAALERRIA--ALARRIRALEQELAALEAEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  362 AELESRYSALEQKHKAEMEEKTSHILSLQKTGQelQSACDALkdqnskLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 441
Cdd:COG4942     86 AELEKEIAELRAELEAQKEELAELLRALYRLGR--QPPLALL------LSPEDFLDAVRRLQYLKYLAPARREQAEELRA 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1483569506  442 FLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQ 519
Cdd:COG4942    158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
978-1608 3.96e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 46.21  E-value: 3.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  978 SKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLkDESKKEIPLSETERGEVEEDKENKEysekcvt 1057
Cdd:PRK03918   187 RTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKLE------- 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1058 SKCQEIEIYLKQTISEKEvELQHIRKDLEEKLAAEEQFQALVKQMNQTLqDKTNQIDLLQAEISENQAIIQKLITSNTda 1137
Cdd:PRK03918   259 EKIRELEERIEELKKEIE-ELEEKVKELKELKEKAEEYIKLSEFYEEYL-DELREIEKRLSRLEEEINGIEERIKELE-- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1138 sdgdsvalvketvvisppctgssehwkpELEEKILALEKEKEQLQKKLqEALTSRKAILKKAQEKERHLrEELKQQKDDY 1217
Cdd:PRK03918   335 ----------------------------EKEERLEELKKKLKELEKRL-EELEERHELYEEAKAKKEEL-ERLKKRLTGL 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1218 N--RLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESnlcpdwps 1295
Cdd:PRK03918   385 TpeKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEE-------- 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1296 HSEDASALQggTSVAQIKAQLKEIEAEKVELElKVSSTTSELTKKSEEVFQLQEQINK-QGLEIESLKTVSHEAEVHAES 1374
Cdd:PRK03918   457 YTAELKRIE--KELKEIEEKERKLRKELRELE-KVLKKESELIKLKELAEQLKELEEKlKKYNLEELEKKAEEYEKLKEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1375 LQqKLESSQLQIAG-LEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAK 1453
Cdd:PRK03918   534 LI-KLKGEIKSLKKeLEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEK 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1454 EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqaalisrkEALKENKSlQEELSLARGTIERLTKSLADVESQVS 1533
Cdd:PRK03918   613 ELEREEKELKKLEEELDKAFEELAETEKRLEELRKEL--------EELEKKYS-EEEYEELREEYLELSRELAGLRAELE 683

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 1534 AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE 1608
Cdd:PRK03918   684 ELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEELTE 758
mukB PRK04863
chromosome partition protein MukB;
154-441 4.27e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 4.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  154 QEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS---------QTQA----------EQA 214
Cdd:PRK04863   347 QEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLAdyqqaldvqQTRAiqyqqavqalERA 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  215 AQLSSMQQVVREKDARFETQVRLHEDELLQLVTQAdvetemQQKLRVLQRKLEEHEESL---------VGRAQVVDLLQQ 285
Cdd:PRK04863   427 KQLCGLPDLTADNAEDWLEEFQAKEQEATEELLSL------EQKLSVAQAAHSQFEQAYqlvrkiageVSRSEAWDVARE 500

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  286 ELTAAEQRnQILSQQLQQMEAEHNTLRNTVETEREESKILLE-KMELEVAErkLSFHNLQEEMHHLLEQFEQAGQAQAEL 364
Cdd:PRK04863   501 LLRRLREQ-RHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEfCKRLGKNL--DDEDELEQLQEELEARLESLSESVSEA 577

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506  365 ESRYSALEQkhkaEMEEKTSHILSLQKTGQELQSACDALKDqnsklLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 441
Cdd:PRK04863   578 RERRMALRQ----QLEQLQARIQRLAARAPAWLAAQDALAR-----LREQSGEEFEDSQDVTEYMQQLLERERELTV 645
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1166-1651 4.85e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 4.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1166 ELEEKILALEKEKEQLQK---KLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1242
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDnieKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1243 IQVREsidgklpsTDQQESCSSTPGLEEPLFKATEQhhtqpvlesnlcpdwpshsedasalqggtsVAQIKAQLKEIEAE 1322
Cdd:TIGR04523  295 SEISD--------LNNQKEQDWNKELKSELKNQEKK------------------------------LEEIQNQISQNNKI 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1323 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTvsheaevHAESLQQKLESSQLQIaglehlRELQPKLDEL 1402
Cdd:TIGR04523  337 ISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK-------ENQSYKQEIKNLESQI------NDLESKIQNQ 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1403 QKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALH---TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEE 1479
Cdd:TIGR04523  404 EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTnqdSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1480 SRAKQQ---IQRKLQAALISRKEALKEN-KSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRL--ALLQEER 1553
Cdd:TIGR04523  484 LEQKQKelkSKEKELKKLNEEKKELEEKvKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkkENLEKEI 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1554 DKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIES---LKSSKIAESTEWQEKHKELQKEYEILLQSYENV 1630
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEkekKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643

                          490       500
                   ....*....|....*....|.
gi 1483569506 1631 SNEAERIQHVVEAVRQEKQEL 1651
Cdd:TIGR04523  644 KQEVKQIKETIKEIRNKWPEI 664
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1310-1781 5.02e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 5.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1310 AQIKAQLKEIEAEKVELELK---VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQI 1386
Cdd:PRK03918   203 EEVLREINEISSELPELREElekLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1387 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDlikalhtqLEMQAKEHDERIKQLQVEL 1466
Cdd:PRK03918   283 KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE--------KEERLEELKKKLKELEKRL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1467 CEMKQKPEEIgEESRAKQQIQRKLQAALISR---------KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNK 1537
Cdd:PRK03918   355 EELEERHELY-EEAKAKKEELERLKKRLTGLtpeklekelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1538 EKDT--VLGRLaLLQEERDKLITEMDRSLLE-NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE------ 1608
Cdd:PRK03918   434 AKGKcpVCGRE-LTEEHRKELLEEYTAELKRiEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKeleekl 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1609 ---WQEKHKELQKEYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1682
Cdd:PRK03918   513 kkyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEkleELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1683 MRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKEcMETLLSSNASMKEELERVKMEYETLSKKF-----QSLMSEKDSL 1757
Cdd:PRK03918   593 RLKELEPFYNEYLELKDAEKELEREEKELKKLEEE-LDKAFEELAETEKRLEELRKELEELEKKYseeeyEELREEYLEL 671

                          490       500
                   ....*....|....*....|....
gi 1483569506 1758 SEEVQDLKHQIEGNVSKQANLEAT 1781
Cdd:PRK03918   672 SRELAGLRAELEELEKRREEIKKT 695
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2105-2690 5.10e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 5.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2105 KLKKELQSNKESVKSQMKQKDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVH-------LEETIGEIQVTLNKKD 2175
Cdd:PRK03918   193 ELIKEKEKELEEVLREINEISSELPELREELEklEKEVKELEELKEEIEELEKELESlegskrkLEEKIRELEERIEELK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2176 KEVQQLQENLDStVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2255
Cdd:PRK03918   273 KEIEELEEKVKE-LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSR-LEEEINGIEERIKELEEKEERLEELKKKLKEL 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2256 KINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyHSSQNELAKLESELKSLKDQLTDLSNSLEK 2335
Cdd:PRK03918   351 EKRLEELEERHELYE-------------------EAKAKKEELERLKK--RLTGLTPEKLEKELEELEKAKEEIEEEISK 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2336 CKEQKGNLEGIIRQQEADIQNSKFSYEQLETdlqASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRqqhdKEI 2415
Cdd:PRK03918   410 ITARIGELKKEIKELKKAIEELKKAKGKCPV---CGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLR----KEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2416 KELENLLSqeeeeNIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQldsfvksmsslqndrdrivgDYQQLEERhlSI 2495
Cdd:PRK03918   483 RELEKVLK-----KESELIKLKELAEQLKELEEKLKKYNLEELEKKAE--------------------EYEKLKEK--LI 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2496 ILEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQyredlnqvitiKDSQQKQLLEVQLQQNKELENKY 2574
Cdd:PRK03918   536 KLKGEIKsLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEE-----------LGFESVEELEERLKELEPFYNEY 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2575 AKLEEKLKESeeanEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEegtlglyhaqlKVKEEEVHRLSALFS 2654
Cdd:PRK03918   605 LELKDAEKEL----EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK-----------KYSEEEYEELREEYL 669

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1483569506 2655 SSQKRIAELEEELvcvqKEAAKKVGEIE---DKLKKELK 2690
Cdd:PRK03918   670 ELSRELAGLRAEL----EELEKRREEIKktlEKLKEELE 704
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1312-1779 6.25e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.78  E-value: 6.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1312 IKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKtvSHEAEVHAESLQQKLESSQlqiaglEH 1391
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN--NQKEQDWNKELKSELKNQE------KK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1392 LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQVELCEMKQ 1471
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNLESQINDLES 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1472 KPEEIGEESrakQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1551
Cdd:TIGR04523  399 KIQNQEKLN---QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1552 ERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKEL-QKEYEILLQSYENV 1630
Cdd:TIGR04523  476 SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIsDLEDELNKDDFELK 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1631 SNEaeriqhvVEAVRQEKQELYGKLRSTEANKKETEKQlqeaeqemeemkekmrkfaksKQQKILELEEENDRLRAEVhp 1710
Cdd:TIGR04523  556 KEN-------LEKEIDEKNKEIEELKQTQKSLKKKQEE---------------------KQELIDQKEKEKKDLIKEI-- 605

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1483569506 1711 agdtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLE 1779
Cdd:TIGR04523  606 ---------EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEII 665
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 48-384 6.51e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 6.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   48 EDVQERLAYAEQLVVELKDIIR---QKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPT 124
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSdasRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  125 EPQ-SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLtqAQAEQPAQSSTEMEEFvmMKQQLQEKEEFISTLQ 203
Cdd:TIGR02169  771 EEDlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARL--REIEQKLNRLTLEKEY--LEKEIQELQEQRIDLK 846

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  204 AQLSQTQAEQA---AQLSSMQQVVREKdarfETQVRLHEDELLQLVTQADvetEMQQKLRVLQRKLEEHEESlvgraqvV 280
Cdd:TIGR02169  847 EQIKSIEKEIEnlnGKKEELEEELEEL----EAALRDLESRLGDLKKERD---ELEAQLRELERKIEELEAQ-------I 912

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  281 DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLqeemhhlleqfeQAGQA 360
Cdd:TIGR02169  913 EKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNM------------LAIQE 980

                          330       340
                   ....*....|....*....|....
gi 1483569506  361 QAELESRYSALEQKHKAEMEEKTS 384
Cdd:TIGR02169  981 YEEVLKRLDELKEKRAKLEEERKA 1004
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1908-2424 6.57e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 6.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1908 EELSRVTKLKETAEEEKDDLE---------ERLMNQLAELNgsignYCQDVTD---AQIKNELLESEMKNLKKCVSELEE 1975
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEpirelaeryAAARERLAELE-----YLRAALRlwfAQRRLELLEAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1976 EKQQLVKEKTKVESEIR--KEYLEKIQGAQKEpgnkshakELQELLKEKQQEVKQLQKDCIRYQEKISALERTV----KA 2049
Cdd:COG4913    310 ELERLEARLDALREELDelEAQIRGNGGDRLE--------QLEREIERLERELEERERRRARLEALLAALGLPLpasaEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2050 LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDL- 2128
Cdd:COG4913    382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELp 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2129 -----------ERRLEQA--------------EEKHLK------EKKNMQEKLDALR-REKVHLEET--------IGEIQ 2168
Cdd:COG4913    462 fvgelievrpeEERWRGAiervlggfaltllvPPEHYAaalrwvNRLHLRGRLVYERvRTGLPDPERprldpdslAGKLD 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2169 VTLNKKDKEVQQ-LQENLD----STVTQLAAFTKSMSSL----QDDRDRVIDEAKKWERK----FS--DAIQSKEEEIRL 2233
Cdd:COG4913    542 FKPHPFRAWLEAeLGRRFDyvcvDSPEELRRHPRAITRAgqvkGNGTRHEKDDRRRIRSRyvlgFDnrAKLAALEAELAE 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2234 KEDNCSVLKDQLRQMSIHMEELKINISRLEH-DKQIWESKAQTEVQLQqkvcdtlqgenkelLSQLEETRHLYHSSQNEL 2312
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRlAEYSWDEIDVASAERE--------------IAELEAELERLDASSDDL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2313 AKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE--TDLQASRELTSRLHEEINMKEQKII 2390
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEdlARLELRALLEERFAAALGDAVEREL 767

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1483569506 2391 SllsgkeEAIQVAIAELRQQHDKEIKELENLLSQ 2424
Cdd:COG4913    768 R------ENLEERIDALRARLNRAEEELERAMRA 795
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 863-1112 6.60e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  863 SSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKFSLGVEIKTLKEQLNL 942
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  943 LSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELA 1022
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1023 NLKDESKKEiplsETERGEVEEDKENKEysekcvtskcqeieiylkQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQM 1102
Cdd:COG4942    175 ELEALLAEL----EEERAALEALKAERQ------------------KLLARLEKELAELAAELAELQQEAEELEALIARL 232

                          250
                   ....*....|
gi 1483569506 1103 NQTLQDKTNQ 1112
Cdd:COG4942    233 EAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2683-2908 6.78e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2683 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDEL 2762
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2763 KRKYDASLKELAQLKEQGLLNrerdALLSETAFsmnSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKA 2842
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLA----LLLSPEDF---LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1483569506 2843 MASLQNERDHLWNELEKFRKSEEGKQRSAAQpstspaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2908
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-307 6.78e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 6.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKakltslnkyieemkaqggtvlpte 125
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA------------------------ 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  126 pQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQaQ 205
Cdd:COG1196    327 -ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLE-E 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  206 LSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ 285
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          250       260
                   ....*....|....*....|..
gi 1483569506  286 ELTAAEQRNQILSQQLQQMEAE 307
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGF 506
PRK12704 PRK12704
phosphodiesterase; Provisional
 2074-2236 6.84e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.15  E-value: 6.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2074 HRKKAQAELASFKVLLDDTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERR--LEQAEEKHLKEKKNMQEKLD 2151
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2152 ALRREKVHLEETIGEiqvtLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDD--RDRVIDEAK-KWERKFSDAIQSKE 2228
Cdd:PRK12704   104 LLEKREEELEKKEKE----LEQKQQELEKKEEELEELIEEQLQELERISGLTAEeaKEILLEKVEeEARHEAAVLIKEIE 179


                   ....*...
gi 1483569506 2229 EEIRLKED 2236
Cdd:PRK12704   180 EEAKEEAD 187
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1373-1602 7.45e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 7.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1373 ESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALtkIQTEIIEQEDLIKALHTQLEmqa 1452
Cdd:COG4913    238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELE--- 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1453 kEHDERIKQLQVELCEMKQKPEEIGeeSRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQV 1532
Cdd:COG4913    313 -RLEARLDALREELDELEAQIRGNG--GDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1533 SAqnkekdtvlgRLALLQEERDKLITEMDRsllenqslssscesLKLALEGLTEDKEKLVKEIESLKSSK 1602
Cdd:COG4913    390 AA----------LLEALEEELEALEEALAE--------------AEAALRDLRRELRELEAEIASLERRK 435
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 152-370 8.27e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 8.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  152 KLQEKEELISTLQAQLTQAQAeQPAQSSTEMEEfvmMKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVRekdarf 231
Cdd:COG4942     42 ELAALKKEEKALLKQLAALER-RIAALARRIRA---LEQELAALEAELAELEKEIAELRAELEAQKEELAELLR------ 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  232 eTQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEEslvgRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTL 311
Cdd:COG4942    112 -ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEELRADLAELAALRAELEAERAELEALLAELEEE 186

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1483569506  312 RNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSA 370
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1061-1523 8.85e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 8.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1061 QEIEIYLKQTISEKEVELQHIrKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDG 1140
Cdd:COG4717     53 KEADELFKPQGRKPELNLKEL-KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLY 131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1141 DSVALVKETVVISPPCtgssehwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRL 1220
Cdd:COG4717    132 QELEALEAELAELPER-------LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1221 QEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQ--ESCSSTPGLEEPLFKATEQHHTQPVLESN---------- 1288
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlKEARLLLLIAAALLALLGLGGSLLSLILTiagvlflvlg 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1289 -LCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKS-EEVFQLQEQINKQGLEIESLKtvsH 1366
Cdd:COG4717    285 lLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEElLELLDRIEELQELLREAEELE---E 361

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1367 EAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEdlikalHT 1446
Cdd:COG4717    362 ELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE------LE 435

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1483569506 1447 QLEMQAKEHDERIKQLQVELCEMKQKPEEIgEESRAKQQIQRKLQAALISRKEALKENKSLQeelsLARGTIERLTK 1523
Cdd:COG4717    436 ELEEELEELEEELEELREELAELEAELEQL-EEDGELAELLQELEELKAELRELAEEWAALK----LALELLEEARE 507
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1450-1739 9.42e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.28  E-value: 9.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1450 MQAKEHDERIKQLQVE-LCEMKQKPEE-IGEESRAKQQIQRKLQAALiSRKEAL-KENKSLQEELSLARGTIERLTKSLA 1526
Cdd:PLN02939   116 QTNSKDGEQLSDFQLEdLVGMIQNAEKnILLLNQARLQALEDLEKIL-TEKEALqGKINILEMRLSETDARIKLAAQEKI 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1527 DVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKE---KLVKEIESLKSS-- 1601
Cdd:PLN02939   195 HVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEErvfKLEKERSLLDASlr 274

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1602 ----KIAESTEWQEKHKELQkeYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETekqlqeaeq 1674
Cdd:PLN02939   275 elesKFIVAQEDVSKLSPLQ--YDCWWEKVENLQDLLDRATNQVEkaaLVLDQNQDLRDKVDKLEASLKEA--------- 343

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 1675 emeEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKME 1739
Cdd:PLN02939   344 ---NVSKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSLE 405
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2105-2619 9.70e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 9.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2105 KLKKELQSNKESVKSQMKQKDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQ 2182
Cdd:PRK02224   199 KEEKDLHERLNGLESELAELDEEIERYEEQREqaRETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELA 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2183 EnldstvtQLAAFTKSMSSLQDDRDRVIDEAKkwerkFSDA-IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISR 2261
Cdd:PRK02224   279 E-------EVRDLRERLEELEEERDDLLAEAG-----LDDAdAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAES 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2262 LEHDKQIWESKAqtevqlqqkvcDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK-------DQLTDLSNSLE 2334
Cdd:PRK02224   347 LREDADDLEERA-----------EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRerfgdapVDLGNAEDFLE 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2335 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSrlheeinmkEQKIisllsgKEEAIQVAIAELRQQHDKE 2414
Cdd:PRK02224   416 ELREERDELREREAELEATLRTARERVEEAEALLEAGKCPEC---------GQPV------EGSPHVETIEEDRERVEEL 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2415 IKELENLLSQEEEENIVLEEEN--KKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERH 2492
Cdd:PRK02224   481 EAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2493 LSIILEKDQLIQEAAAENNKL---KEEIRGLRSHMDDLnSENAKLDAELIQYREDLNQVITIKDsQQKQLLEVQLQQNKE 2569
Cdd:PRK02224   561 AEAEEEAEEAREEVAELNSKLaelKERIESLERIRTLL-AAIADAEDEIERLREKREALAELND-ERRERLAEKRERKRE 638

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 2570 LENKYAKLEEKLKESEEAN-----EDLRRSFNALQEEKQDLSKEIESLKVSISQL 2619
Cdd:PRK02224   639 LEAEFDEARIEEAREDKERaeeylEQVEEKLDELREERDDLQAEIGAVENELEEL 693
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1314-1777 9.80e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 9.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1314 AQLKEIEAEKVELElkvsSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQiaglEHLR 1393
Cdd:COG4717     71 KELKELEEELKEAE----EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALE----AELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1394 ELQPKLDELQ---KLISKKEEDVSYLSGQLSEKEAALTKI--QTEIIEQEDLIKAL--HTQLEMQAKEHDERIKQLQVEL 1466
Cdd:COG4717    143 ELPERLEELEerlEELRELEEELEELEAELAELQEELEELleQLSLATEEELQDLAeeLEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1467 CEMKQKPEEIGEESRAKQQIQR----KLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKekdtv 1542
Cdd:COG4717    223 EELEEELEQLENELEAAALEERlkeaRLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREK----- 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1543 lgrlALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSS-KIAESTEWQEKHKELQKEYE 1621
Cdd:COG4717    298 ----ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELlREAEELEEELQLEELEQEIA 373

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1622 ILLQSYeNVSNEAERIQHVVEAvrQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRkfAKSKQQKILELEEEN 1701
Cdd:COG4717    374 ALLAEA-GVEDEEELRAALEQA--EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE--LEELEEELEELEEEL 448

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1483569506 1702 DRLRAEVhpagDTAKECMETLLSSN--ASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1777
Cdd:COG4717    449 EELREEL----AELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 798-1029 9.83e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 9.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  798 LLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 877
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  878 LEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEI----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAE 947
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  948 EAKKEQVEEDNEVSSGLKQNYDEMspagqisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 1027
Cdd:COG4942    170 EAERAELEALLAELEEERAALEAL-------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242


                   ..
gi 1483569506 1028 SK 1029
Cdd:COG4942    243 TP 244
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2012-2536 9.86e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 9.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2012 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERtvkalefvqtesqkdleiTKENLAQAVEHRKKAQAELASFKVLLDD 2091
Cdd:PRK02224   201 EKDLHERLNGLESELAELDEEIERYEEQREQARE------------------TRDEADEVLEEHEERREELETLEAEIED 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2092 TQSEAARVladnlklKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK--EKKNMQEKLDALRREKVHLEETIGEIQV 2169
Cdd:PRK02224   263 LRETIAET-------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDdaDAEAVEARREELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2170 TLNKKDKEVQQLQENLDstvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMS 2249
Cdd:PRK02224   336 AAQAHNEEAESLREDAD----DLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2250 IHMEELKINISRLEhdkqiwESKAQTEVQLQQkVCDTLQgENKELLSQ---------LEETRHL--YHSSQNELAKLESE 2318
Cdd:PRK02224   412 DFLEELREERDELR------EREAELEATLRT-ARERVE-EAEALLEAgkcpecgqpVEGSPHVetIEEDRERVEELEAE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2319 LKSLKDQLTDLSNSL-------------EKCKEQKGNLEGIIRQQEADIQNSKFSYEQ-------LETDLQASRELTSRL 2378
Cdd:PRK02224   484 LEDLEEEVEEVEERLeraedlveaedriERLEERREDLEELIAERRETIEEKRERAEElreraaeLEAEAEEKREAAAEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2379 HEEINMKEQKIISLlsgkeEAIQVAIAELRQQHDKeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENI 2458
Cdd:PRK02224   564 EEEAEEAREEVAEL-----NSKLAELKERIESLER-IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKR 637

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1483569506 2459 QQKAQLDSfvKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLkEEIRGLRSHMDDLNSENAKLDA 2536
Cdd:PRK02224   638 ELEAEFDE--ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL-EELEELRERREALENRVEALEA 712
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1821-2056 1.02e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.92  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1821 PSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK-----EFSQTLENEKNTLLSQISTKDGELKMLQEE 1895
Cdd:PRK05771    36 LKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEELEKIEKEIKELEEEISELENE 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1896 VTKmnllnqqIQEELSRVTKLKETAEEEKDDLEERLMNQLAelnGSI--GNYCQDVTDAQIKNELLESEMKN-------- 1965
Cdd:PRK05771   116 IKE-------LEQEIERLEPWGNFDLDLSLLLGFKYVSVFV---GTVpeDKLEELKLESDVENVEYISTDKGyvyvvvvv 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1966 LKKCVSELEEE--KQQLVKEKTKVE---SEIRKEYLEKIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQ--- 2037
Cdd:PRK05771   186 LKELSDEVEEElkKLGFERLELEEEgtpSELIREIKEELEEIEKE------RESLLEELKELAKKYLEELLALYEYLeie 259

                          250       260
                   ....*....|....*....|
gi 1483569506 2038 -EKISALERTVKALEFVQTE 2056
Cdd:PRK05771   260 lERAEALSKFLKTDKTFAIE 279
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
48-532 1.04e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506   48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQKD-EALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGtvlptep 126
Cdd:COG4913    265 AAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG------- 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  127 QSEEQLSKhdkssteeemEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAqsstEMEEFVMMKQQLQEKEEFISTLQAQL 206
Cdd:COG4913    338 DRLEQLER----------EIERLERELEERERRRARLEALLAALGLPLPA----SAEEFAALRAEAAALLEALEEELEAL 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  207 SQTQAEQAAQLSSMQQVVREKdarfetqvrlhEDELLQLVTQAD-VETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQ 285
Cdd:COG4913    404 EEALAEAEAALRDLRRELREL-----------EAEIASLERRKSnIPARLLALRDALAEALGLDEAELPFVGELIEVRPE 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  286 EL---TAAE-----QRNQIL--SQQLQQMEA--EHNTLRNTVETEREESKILLEKMELEVAE---RKLSF--HNLQEEMH 348
Cdd:COG4913    473 EErwrGAIErvlggFALTLLvpPEHYAAALRwvNRLHLRGRLVYERVRTGLPDPERPRLDPDslaGKLDFkpHPFRAWLE 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  349 HLL------------EQFEQAGQA-----QAelesrysaleqKHKAEMEEK--TSHILSLQKTGQelqsacdalkdQNSK 409
Cdd:COG4913    553 AELgrrfdyvcvdspEELRRHPRAitragQV-----------KGNGTRHEKddRRRIRSRYVLGF-----------DNRA 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  410 LLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRlpLQQHETASQTSFPDVynegtqavteeNIASLQKRVVELENEK 489
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDALQER--REALQRLAEYSWDEI-----------DVASAEREIAELEAEL 677

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|...
gi 1483569506  490 GALLLSSIELEELKAENEKLSSQITllEAQNRTGEADREVSEI 532
Cdd:COG4913    678 ERLDASSDDLAALEEQLEELEAELE--ELEEELDELKGEIGRL 718
PRK12704 PRK12704
phosphodiesterase; Provisional
 197-368 1.05e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.77  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  197 EFISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQvrlheDELLQLVTQADVE-TEMQQKLRVLQRKLEEHEESLVG 275
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAK-----EEIHKLRNEFEKElRERRNELQKLEKRLLQKEENLDR 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  276 RAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETE--------REESK-ILLEKMELEvaerklsfhnLQEE 346
Cdd:PRK12704   101 KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQElerisgltAEEAKeILLEKVEEE----------ARHE 170

                          170       180
                   ....*....|....*....|..
gi 1483569506  347 MHHLLEQFEQAGQAQAELESRY 368
Cdd:PRK12704   171 AAVLIKEIEEEAKEEADKKAKE 192
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2290-2667 1.11e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2290 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFS--YEQLETD 2367
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2368 LQASREL---TSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHD---KEIKELENLLSQEEEENIVLEEeNKKAVD 2441
Cdd:COG4717    155 LEELRELeeeLEELEAELAELQEELEELLEQLSLATEEELQDLAEELEelqQRLAELEEELEEAQEELEELEE-ELEQLE 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2442 KTNQLMETLKTIKKENIQQKA------------QLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAE 2509
Cdd:COG4717    234 NELEAAALEERLKEARLLLLIaaallallglggSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2510 NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKElenkyakleEKLKESEEANE 2589
Cdd:COG4717    314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA---------ALLAEAGVEDE 384

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1483569506 2590 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEEL 2667
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAEL 462
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1335-1767 1.17e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1335 SELTKKSEEVFQLQEQINKQGL-EIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDV 1413
Cdd:COG4717     49 ERLEKEADELFKPQGRKPELNLkELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1414 SYLSgQLSEKEAALTKIQTEIIEQEDLIKALHtQLEMQAKEHDERIKQLQVELCEMKQKPEEigEESRAKQQIQRKLQAA 1493
Cdd:COG4717    129 PLYQ-ELEALEAELAELPERLEELEERLEELR-ELEEELEELEAELAELQEELEELLEQLSL--ATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1494 LISRKEALKENKSLQEELSLARGTIERLTKSLADVESQvsAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSS 1573
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALE--ERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1574 CESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELyg 1653
Cdd:COG4717    283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE-- 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1654 klrsTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLlsSNASMKEEL 1733
Cdd:COG4717    361 ----EELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL--DEEELEEEL 434

                          410       420       430
                   ....*....|....*....|....*....|....
gi 1483569506 1734 ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQ 1767
Cdd:COG4717    435 EELEEELEELEEELEELREELAELEAELEQLEED 468
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
688-1120 1.18e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  688 QDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADN-------NSSAFTALSEERDQLLSQVKE 760
Cdd:PRK02224   250 REELETLEAEIEDLRETIAET----EREREELAEEVRDLRERLEELEEERDDllaeaglDDADAEAVEARREELEDRDEE 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  761 L-SMVTELRAQVKQLEmNLAEAERQRRLDYESQTAHdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 839
Cdd:PRK02224   326 LrDRLEECRVAAQAHN-EEAESLREDADDLEERAEE---LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  840 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKK-----RDVE--TLQQTIEEKDQQVTEis 912
Cdd:PRK02224   402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEgsPHVETIEEDRERVEE-- 479

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  913 fsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK--EQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLK 990
Cdd:PRK02224   480 ---------LEAELEDLEEEVEEVEERLERAEDLVEAEDriERLEERREDLEELIAERRETIEEKRERAEELRERAAELE 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  991 KENEQRKRKLQAALINRKELLQRVSRLEEELANLKD--ESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLK 1068
Cdd:PRK02224   551 AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKEriESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLA 630

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 1069 QT---ISEKEVELQHIRkdLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEI 1120
Cdd:PRK02224   631 EKrerKRELEAEFDEAR--IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEI 683
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2805-3119 1.20e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2805 LSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQpstspaevqsL 2884
Cdd:COG1196    231 LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR----------L 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2885 KKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELhplKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSW 2964
Cdd:COG1196    301 EQDIARLEERRRELEERLEELEEELAELEEELEEL---EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2965 EIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPdgsqnlvyETELLRTQLNDSLK 3044
Cdd:COG1196    378 EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE--------EEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 3045 EIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNhcavLEKQVQELQAGPLNIDVAPGAP 3119
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE----AEADYEGFLEGVKAALLLAGLR 520
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1581-1993 1.31e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1581 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEillqSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1660
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEE----EYAELQEELEELEEELEELEAELEELREELEKLEK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1661 NKKETEKQLQEAEQEMEEMKEKMR-KFAKSKQQKILELEEENDRLRAEVHpagDTAKECMETLLSSNASMKEELERVKME 1739
Cdd:COG4717    124 LLQLLPLYQELEALEAELAELPERlEELEERLEELRELEEELEELEAELA---ELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1740 YETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTN----------VTEEGTQSIPGETEEQDSLS 1809
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallaLLGLGGSLLSLILTIAGVLF 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1810 MSTRPTCSESVPSAKSANPAVSK----DFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLEnEKNTLLSQISTK 1885
Cdd:COG4717    281 LVLGLLALLFLLLAREKASLGKEaeelQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEEL 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1886 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER--LMNQLAELNGSIGNYCQDVTDAQIKNELLESEM 1963
Cdd:COG4717    360 EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELeeLEEQLEELLGELEELLEALDEEELEEELEELEE 439

                          410       420       430
                   ....*....|....*....|....*....|
gi 1483569506 1964 KnlkkcVSELEEEKQQLVKEKTKVESEIRK 1993
Cdd:COG4717    440 E-----LEELEEELEELREELAELEAELEQ 464
46 PHA02562
endonuclease subunit; Provisional
 1850-2139 1.33e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1850 LKERIAGLEEEkqknkefSQTLENEKNTLLSQISTKdgelKMLQEEVTKMNllNQQIQEELSRVTKLKETAEEEKDDLEE 1929
Cdd:PHA02562   172 NKDKIRELNQQ-------IQTLDMKIDHIQQQIKTY----NKNIEEQRKKN--GENIARKQNKYDELVEEAKTIKAEIEE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1930 rLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEE------KQQLVKEKTKVESeirkeylekiqgaq 2003
Cdd:PHA02562   239 -LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITK-------------- 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2004 kepgNKSHAKELQ---ELLKEKQQEVKQLqkdciryqeKISALERTVKALEFvqtesQKDLEITKENLAQAVEHRKKAQA 2080
Cdd:PHA02562   304 ----IKDKLKELQhslEKLDTAIDELEEI---------MDEFNEQSKKLLEL-----KNKISTNKQSLITLVDKAKKVKA 365

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1483569506 2081 ELAsfkvllddtqseaarvladnlKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKH 2139
Cdd:PHA02562   366 AIE---------------------ELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKY 403
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2019-2230 1.38e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2019 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAAR 2098
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2099 VLADNLKLKKELQS-------NKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTL 2171
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1483569506 2172 NKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2230
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1498-2266 1.78e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.19  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1498 KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESL 1577
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1578 KLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1657
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1658 TEAN----KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTaKECMETLLSSNASMKEEL 1733
Cdd:pfam02463  336 EIEElekeLKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEE-LELKSEEEKEAQLLLELA 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1734 ERVKMEYETLSKK-------------FQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHdnqtNVTEEGTQSIPG 1800
Cdd:pfam02463  415 RQLEDLLKEEKKEeleileeeeesieLKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ----LVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1801 ETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1880
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1881 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLK------ETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQI 1954
Cdd:pfam02463  571 TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQldkatlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1955 KNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCI 2034
Cdd:pfam02463  651 GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2035 RYQEKISALERTVKALEFVQTEsqkDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK 2114
Cdd:pfam02463  731 QDKINEELKLLKQKIDEEEEEE---EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2115 ESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeiqvTLNKKDKEVQQLQENLDSTVTQLAA 2194
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELE-----RLEEEITKEELLQELLLKEEELEEQ 882

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1483569506 2195 FTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDK 2266
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENN 954
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1316-1783 1.78e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.28  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1316 LKEIEAEKVELElkvssttsELTKKSEEVfqlQEQINKQGLEIE---------SLKTVSHEAEVHA--------ESLQQK 1378
Cdd:PRK03918   171 IKEIKRRIERLE--------KFIKRTENI---EELIKEKEKELEevlreineiSSELPELREELEKlekevkelEELKEE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1379 LESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSylsgQLSEKEAALTKIQTEIIEQEDLIKALH------TQLEMQ 1451
Cdd:PRK03918   240 IEELEKELESLEgSKRKLEEKIRELEERIEELKKEIE----ELEEKVKELKELKEKAEEYIKLSEFYEeyldelREIEKR 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1452 AKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqAALISRKEALKENKSLQEEL-----SLARGTIERLTKSLA 1526
Cdd:PRK03918   316 LSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRL-EELEERHELYEEAKAKKEELerlkkRLTGLTPEKLEKELE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1527 DVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRsllenqsLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIA-E 1605
Cdd:PRK03918   395 ELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEkE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1606 STEWQEKHKELQKEyeilLQSYENVSNEAERIQHVVEAVRQEKqELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK 1685
Cdd:PRK03918   468 LKEIEEKERKLRKE----LRELEKVLKKESELIKLKELAEQLK-ELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIK 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1686 FAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLK 1765
Cdd:PRK03918   543 SLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELK 622

                          490
                   ....*....|....*...
gi 1483569506 1766 HQIEGNVSKQANLEATEK 1783
Cdd:PRK03918   623 KLEEELDKAFEELAETEK 640
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2271-2480 1.96e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2271 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ 2350
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2351 EADIQ-NSKFSYEQL----ETDLQASRELtsRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQE 2425
Cdd:COG4942    110 LRALYrLGRQPPLALllspEDFLDAVRRL--QYLKYLAPARREQAEELRADLAELAALRAELEAER-AELEALLAELEEE 186

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 2426 EEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDR 2480
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2448-2666 2.01e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2448 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2527
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2528 NSENAKLDAELIQ-----YREDLNQVITIKDSQQ------------KQLLEVQLQQNKELENKYAKLEEKLKESEEANED 2590
Cdd:COG4942     96 RAELEAQKEELAEllralYRLGRQPPLALLLSPEdfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1483569506 2591 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhAQLKVKEEEVHRLSALFSSSQKRIAELEEE 2666
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELA---------AELAELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1067-1251 2.07e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1067 LKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL---ITSNTDASDGDSV 1143
Cdd:COG4942     32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELraeLEAQKEELAELLR 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1144 ALVKETVVISPPCTGSSEHWK-------------PELEEKILALEKEKEQLQkKLQEALTSRKAILKKAQEKERHLREEL 1210
Cdd:COG4942    112 ALYRLGRQPPLALLLSPEDFLdavrrlqylkylaPARREQAEELRADLAELA-ALRAELEAERAELEALLAELEEERAAL 190

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1483569506 1211 KQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1251
Cdd:COG4942    191 EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1338-1765 2.14e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1338 TKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE-SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYL 1416
Cdd:pfam15921  408 TGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAK 487

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1417 SGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelcEMKQKpeeiGEESRAKQQIQRKLQAALIS 1496
Cdd:pfam15921  488 KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ----HLKNE----GDHLRNVQTECEALKLQMAE 559

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1497 RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLlenqslsSSCES 1576
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARV-------SDLEL 632

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1577 LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLR 1656
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1657 STEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHpagdtakecmeTLLSSNASMKEELERV 1736
Cdd:pfam15921  713 NTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKH-----------FLKEEKNKLSQELSTV 781

                          410       420
                   ....*....|....*....|....*....
gi 1483569506 1737 KMEYETLSKKFQSLMSEKDSLSEEVQDLK 1765
Cdd:pfam15921  782 ATEKNKMAGELEVLRSQERRLKEKVANME 810
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 284-1089 2.29e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 43.81  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  284 QQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEvaerklsfhnlQEEMHHLLEQFEQAGQAQAE 363
Cdd:pfam02463  215 LKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKE-----------EEKLAQVLKENKEEEKEKKL 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  364 LESRYSALEQKHKAEMEEKTSHILSLQKTGQELQsacdALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFL 443
Cdd:pfam02463  284 QEEELKLLAKEEEELKSELLKLERRKVDDEEKLK----ESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  444 NRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTG 523
Cdd:pfam02463  360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESI 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  524 EADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEM 603
Cdd:pfam02463  440 ELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDG 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  604 KQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDI 683
Cdd:pfam02463  520 VGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEI 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  684 GQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK------------AKEISNLNQLIEEFKKNADNNSSAFTALSEER 751
Cdd:pfam02463  600 DPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTklkesakakesgLRKGVSLEEGLAEKSEVKASLSELTKELLEIQ 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  752 DQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQF 831
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  832 SEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQT-IEEKDQQVTE 910
Cdd:pfam02463  760 EEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEkIKEEELEELA 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  911 ISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLK 990
Cdd:pfam02463  840 LELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEI 919

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  991 KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDES-KKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQ 1069
Cdd:pfam02463  920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEeEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKER 999

                          810       820
                   ....*....|....*....|
gi 1483569506 1070 TISEKEVELQHIRKDLEEKL 1089
Cdd:pfam02463 1000 LEEEKKKLIRAIIEETCQRL 1019
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2310-2935 2.42e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.86  E-value: 2.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2310 NELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI 2389
Cdd:TIGR04523   40 KKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQK 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2390 ISLlsgkeeaiqvaiaelrqqhDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVK 2469
Cdd:TIGR04523  120 NKL-------------------EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2470 SMSSLQNDRDRIVGDYQQLEERhLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVI 2549
Cdd:TIGR04523  181 EKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLK 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2550 TIKDSQQKQLLEVQLQQNKElenkyakleeklkeseeanedlrrsfnalQEEKQDLSKEIESLKVSISQLTRQvtalQEE 2629
Cdd:TIGR04523  260 DEQNKIKKQLSEKQKELEQN-----------------------------NKKIKELEKQLNQLKSEISDLNNQ----KEQ 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2630 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEiEDKLKKELKHLHHDAGIMRNETETAEER 2709
Cdd:TIGR04523  307 DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESE-NSEKQRELEEKQNEIEKLKKENQSYKQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2710 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQ-GLLNRERDA 2788
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIiKNLDNTRES 465

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2789 L---LSETAFSMNSTEENslshLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL-------- 2857
Cdd:TIGR04523  466 LetqLKVLSRSINKIKQN----LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKkekeskis 541

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2858 ---EKFRKSEEGKQRSA--AQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDK 2932
Cdd:TIGR04523  542 dleDELNKDDFELKKENleKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEK 621


                   ...
gi 1483569506 2933 TKA 2935
Cdd:TIGR04523  622 AKK 624
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2701-2928 2.75e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2701 NETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQg 2780
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE- 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2781 lLNRERDALlsetafsmnsteENSLSHLEKLNQQllsKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKF 2860
Cdd:COG4942     99 -LEAQKEEL------------AELLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1483569506 2861 RKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKEL----KNLQQQYLQINQEITELHPLKAQLQE 2928
Cdd:COG4942    163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLekelAELAAELAELQQEAEELEALIARLEA 234
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 665-1241 2.76e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 43.89  E-value: 2.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  665 ELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAqeIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAF 744
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLL 1196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  745 TALSE-ERDQL-LSQVKELSMVTELRAQVKQLEmNLAEAERQRRLDYESQTAH----DNLLTEQIHSLSIEAKSKDVK-- 816
Cdd:TIGR01612 1197 NEIAEiEKDKTsLEEVKGINLSYGKNLGKLFLE-KIDEEKKKSEHMIKAMEAYiedlDEIKEKSPEIENEMGIEMDIKae 1275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  817 IEVLQNELDDVQLQFSEQSTLIRSLqSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVET 896
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNI 1354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  897 LQ-QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLlsRAEEAKKEQVEEDNEVSsGLKQNYDEMSPAG 975
Cdd:TIGR01612 1355 LKlNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINL--EECKSKIESTLDDKDID-ECIKKIKELKNHI 1431

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  976 QISKEELQHEFDLLKKENEQrkrklqaALINRKELLQRVSRLEEELANLKDESKKEIPLSetergeVEEDKENKEYSEKC 1055
Cdd:TIGR01612 1432 LSEESNIDTYFKNADENNEN-------VLLLFKNIEMADNKSQHILKIKKDNATNDHDFN------INELKEHIDKSKGC 1498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1056 VTskcqEIEIYLKQTISEKEVELQHiRKDLEE------KLAAEEQFQALVKQMNQTL---QDKTNQIdLLQAEISENQ-- 1124
Cdd:TIGR01612 1499 KD----EADKNAKAIEKNKELFEQY-KKDVTEllnkysALAIKNKFAKTKKDSEIIIkeiKDAHKKF-ILEAEKSEQKik 1572

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1125 AIIQKLITSNTDASDGD--SVALVKETVVISPpctgssehwkpeLEEKILALEkekeQLQKKLQEALTSRKAILKKAQEK 1202
Cdd:TIGR01612 1573 EIKKEKFRIEDDAAKNDksNKAAIDIQLSLEN------------FENKFLKIS----DIKKKINDCLKETESIEKKISSF 1636

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1483569506 1203 ERHLRE-ELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1241
Cdd:TIGR01612 1637 SIDSQDtELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
254-441 2.82e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  254 EMQQKLRVLQRKLEEH--EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMEL 331
Cdd:COG3206    186 ELRKELEEAEAALEEFrqKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVI 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  332 EVAERKLSfhNLQEEMHHLLEQF----EQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQN 407
Cdd:COG3206    266 QQLRAQLA--ELEAELAELSARYtpnhPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARL 343

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1483569506  408 SKLLQDKNEQAV--QSAQTIQQLEDQLQQKSKEISQ 441
Cdd:COG3206    344 AELPELEAELRRleREVEVARELYESLLQRLEEARL 379
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 837-1240 2.85e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 2.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  837 LIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKM------DQLLLEKKRDVETLQQTIEEKDQQVTE 910
Cdd:pfam05483  364 LLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELkkilaeDEKLLDEKKQFEKIAEELKGKEQELIF 443

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  911 ISFSMTEKMVQLNEEKFSLGV-EIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLL 989
Cdd:pfam05483  444 LLQAREKEIHDLEIQLTAIKTsEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDII 523

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  990 --KKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYL 1067
Cdd:pfam05483  524 ncKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQI 603

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1068 KQTISEKEvELQHIRKDLEEKLAAEE--------QFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASd 1139
Cdd:pfam05483  604 ENKNKNIE-ELHQENKALKKKGSAENkqlnayeiKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAK- 681

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1140 gdsvALVKETVVISPPCTGSSEHwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKER---HLREELKQQKDD 1216
Cdd:pfam05483  682 ----AIADEAVKLQKEIDKRCQH---KIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSakaALEIELSNIKAE 754

                          410       420
                   ....*....|....*....|....
gi 1483569506 1217 YNRLQEQFDEQSKENENIGDQLRQ 1240
Cdd:pfam05483  755 LLSLKKQLEIEKEEKEKLKMEAKE 778
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1845-2084 2.89e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1845 QQIDQLKERIAGLEEE----KQKNKEFSqtLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRvtKLKETA 1920
Cdd:COG3206    182 EQLPELRKELEEAEAAleefRQKNGLVD--LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS--GPDALP 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1921 EEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQiknelleSEMKNLKkcvSELEEEKQQLVKEKTKVESEIRKEYLekiq 2000
Cdd:COG3206    258 ELLQSPVIQQLRAQLAELEAELAELSARYTPNH-------PDVIALR---AQIAALRAQLQQEAQRILASLEAELE---- 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2001 gaqkepGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERtvkalefvqtesqkDLEITKENLAQAVEHRKKAQA 2080
Cdd:COG3206    324 ------ALQAREASLQAQLAQLEARLAELPEL----EAELRRLER--------------EVEVARELYESLLQRLEEARL 379


                   ....
gi 1483569506 2081 ELAS 2084
Cdd:COG3206    380 AEAL 383
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1838-2071 3.08e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 3.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1838 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKmnlLNQQIQEelsRVTKLK 1917
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAE---AEAEIEE---RREELG 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1918 ETAEEEKddLEERLMNQLAELNGSignycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEirkeyLE 1997
Cdd:COG3883     90 ERARALY--RSGGSVSYLDVLLGS-----ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAK-----LA 157

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1483569506 1998 KIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2071
Cdd:COG3883    158 ELEALKAE--LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1962-2394 3.12e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.53  E-value: 3.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1962 EMKNLKKCVSEL--EEEKQQLVKEKTKVESEIRKEYLekIQGAQKEPGNKSHAKEL--QELLKEKQQEVKQLQKDCIRYQ 2037
Cdd:COG5022    811 EYRSYLACIIKLqkTIKREKKLRETEEVEFSLKAEVL--IQKFGRSLKAKKRFSLLkkETIYLQSAQRVELAERQLQELK 888

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2038 E---KISALERTVKALEFVQTESQKDLEitkENLAQAVEHRKKAQAELasfKVLLDDTQSEaarvladnlklkkeLQSNK 2114
Cdd:COG5022    889 IdvkSISSLKLVNLELESEIIELKKSLS---SDLIENLEFKTELIARL---KKLLNNIDLE--------------EGPSI 948

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2115 ESVKSQMKQKDEDLERRLEQAEEkhlkEKKNMQEKLDALRREkvhleetigeiqvtLNKKDKEVQQLQENLDSTVTQLAA 2194
Cdd:COG5022    949 EYVKLPELNKLHEVESKLKETSE----EYEDLLKKSTILVRE--------------GNKANSELKNFKKELAELSKQYGA 1010

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2195 FTKSMSSLQDdRDRVIDEAKKWERKFSDaiQSKEEEIRLKEDNC-SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKA 2273
Cdd:COG5022   1011 LQESTKQLKE-LPVEVAELQSASKIISS--ESTELSILKPLQKLkGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLE 1087

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2274 QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESElKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ---- 2349
Cdd:COG5022   1088 STENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEIS-KFLSQLVNTLEPVFQKLSVLQLELDGLFWEanle 1166

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1483569506 2350 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLS 2394
Cdd:COG5022   1167 ALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLKNELIALFS 1211
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2408-2625 3.13e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2408 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDY-- 2485
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELae 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2486 -----QQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdaeliqyrEDLNQVITIKDSQQKQLL 2560
Cdd:COG4942    109 llralYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 2561 EVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTA 2625
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 463-1250 3.37e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 3.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  463 YNEGTQAVTEENIASLQKRVVELENEKGALLLS----SIELEELKAENEKLSSQITLLEAQNrtGEADREVSEIsivdia 538
Cdd:TIGR02168  215 YKELKAELRELELALLVLRLEELREELEELQEElkeaEEELEELTAELQELEEKLEELRLEV--SELEEEIEEL------ 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  539 nkrsssaeesgQDVLENTfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEgiapikmkv 618
Cdd:TIGR02168  287 -----------QKELYAL-ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK--------- 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  619 fLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTsEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQI 698
Cdd:TIGR02168  346 -LEELKEELESLEAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  699 LELELNFHKAQ-EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMN 777
Cdd:TIGR02168  424 EELLKKLEEAElKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  778 LAEAERQRRLDYESQTAHDNLLTEQIH-----SLSIEA----KSKDVKIEVLQNELDDVQLQFSEQS------------- 835
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILGVLSELISvdegyEAAIEAalggRLQAVVVENLNAAKKAIAFLKQNELgrvtflpldsikg 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  836 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRdvETLQQTIEEKDQQVTEISFSM 915
Cdd:TIGR02168  584 TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDGDLVRPGGVI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  916 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEdnevSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQ 995
Cdd:TIGR02168  662 TGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  996 RKRKLQAalinrkeLLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIyLKQTISEKE 1075
Cdd:TIGR02168  738 LEAEVEQ-------LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA-LREALDELR 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1076 VELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPP 1155
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1156 CTGSSEhwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1235
Cdd:TIGR02168  890 ALLRSE--LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE 967

                          810
                   ....*....|....*
gi 1483569506 1236 DQLRQLQIQVRESID 1250
Cdd:TIGR02168  968 EEARRRLKRLENKIK 982
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2112-2724 3.41e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.29  E-value: 3.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2112 SNKESVKSQMKQKDEDLERRLEqaEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQvTLNKKDKEVQQLQENLDSTV-T 2190
Cdd:pfam12128  207 EDDGVVPPKSRLNRQQVEHWIR--DIQAIAGIMKIRPEFTKLQQEFNTLESAELRLS-HLHFGYKSDETLIASRQEERqE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2191 QLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKD-----------QLRQMSIHMEELKINI 2259
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDadietaaadqeQLPSWQSELENLEERL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2260 SRLEHDKQIWESKAQTEVQLQQKVC-DTLQGENKELLSQLEETRHLYHSSQNELAKLESELKS-LKDQLTDLSNSLEKCK 2337
Cdd:pfam12128  364 KALTGKHQDVTAKYNRRRSKIKEQNnRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREqLEAGKLEFNEEEYRLK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2338 EQKGNLEGIIRQQEADiqnskfsyEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQQHDKEIKE 2417
Cdd:pfam12128  444 SRLGELKLRLNQATAT--------PELLLQLENFDERIERAREEQEAANAEV--------ERLQSELRQARKRRDQASEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2418 LENLLSQEEEENIVLEEENKKAVDKTNQLMETLKtikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHL-SII 2496
Cdd:pfam12128  508 LRQASRRLEERQSALDELELQLFPQAGTLLHFLR---KEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLyGVK 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2497 LEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYredlnqvitikdsqqkqllevqlqqNKELENKYA 2575
Cdd:pfam12128  585 LDLKRIdVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQA-------------------------NGELEKASR 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2576 KLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLK----VSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLS- 2650
Cdd:pfam12128  640 EETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKdsanERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAy 719

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1483569506 2651 --ALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDagimrnetetaEERVAELARDLVEMEQKL 2724
Cdd:pfam12128  720 wqVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVD-----------PDVIAKLKREIRTLERKI 784
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1166-1242 3.49e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 3.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1166 ELEEKILALEKEKEQLQKKLQEALTSRKAILKK----AQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1241
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDelaeLEEELEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494


                   .
gi 1483569506 1242 Q 1242
Cdd:COG0542    495 A 495
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1919-2150 3.58e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 3.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1919 TAEEEKDDLEERLMN----QLAELNGSIGNYcqdvtdaqiKNELLESEMKNLKKCVSELEEEKQqlvKEKTKVESEIRKE 1994
Cdd:PRK05771    13 TLKSYKDEVLEALHElgvvHIEDLKEELSNE---------RLRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1995 YLEKIQGAQKEPGNKShakELQELLKEKQQEVKQLQKDCIRYQEKISALE---------------RTVKA---------- 2049
Cdd:PRK05771    81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlslllgfKYVSVfvgtvpedkl 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2050 LEFVQTESQKDLEITKEN-------LAQAVEHRKKAQAELASFKVLLDDTQSE--AARVLADNLKLKKELQSNKESVKSQ 2120
Cdd:PRK05771   158 EELKLESDVENVEYISTDkgyvyvvVVVLKELSDEVEEELKKLGFERLELEEEgtPSELIREIKEELEEIEKERESLLEE 237

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1483569506 2121 MKQKDEDLERRLEQAEEK--HLKEKKNMQEKL 2150
Cdd:PRK05771   238 LKELAKKYLEELLALYEYleIELERAEALSKF 269
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 714-1251 3.61e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 3.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  714 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELsmvtelRAQVKQLEMNLAEAERQRrLDYESQT 793
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDL------KKQKEELENELNLLEKEK-LNIQKNI 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  794 AHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQAL 873
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  874 SQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKF---------------SLGVEIKTLKE 938
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLeeiqnqisqnnkiisQLNEQISQLKK 349

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  939 QLNLLSRAEEAKKEQVEEDNEVSSGLK---QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS 1015
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKkenQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1016 RLEEELANLKDESKkeiplsetergeveeDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQF 1095
Cdd:TIGR04523  430 RLKETIIKNNSEIK---------------DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1096 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL----ITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEE-- 1169
Cdd:TIGR04523  495 EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLesekKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEElk 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1170 -KILALEKEKEQLQKKLQEALTSRKAILKKAQEKERhLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1248
Cdd:TIGR04523  575 qTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEK-KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653


                   ...
gi 1483569506 1249 IDG 1251
Cdd:TIGR04523  654 IKE 656
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2288-2919 3.91e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.97  E-value: 3.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2288 QGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLegiiRQQEADIQNSKFSYEQLETD 2367
Cdd:PRK01156   137 QGEMDSLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKL----KSSNLELENIKKQIADDEKS 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2368 LQASRELTSRLHEEINMKEQKIISLLSGKEEAIqvAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLM 2447
Cdd:PRK01156   213 HSITLKEIERLSIEYNNAMDDYNNLKSALNELS--SLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPV 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2448 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDrdrivgdyqqleerhlsiiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2527
Cdd:PRK01156   291 YKNRNYINDYFKYKNDIENKKQILSNIDAE-------------------INKYHAIIKKLSVLQKDYNDYIKKKSRYDDL 351

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2528 NSENAKLDAELIQYREDLNQVITIKDSQQkqllevqlQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSK 2607
Cdd:PRK01156   352 NNQILELEGYEMDYNSYLKSIESLKKKIE--------EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISS 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2608 EIESLKVSISQLTRQVTALQEEGTLGLYHAQLKV-----KEEEVHRLSALFSSSQKRiaeLEEELVCVQKEAAKkvgeIE 2682
Cdd:PRK01156   424 KVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVcgttlGEEKSNHIINHYNEKKSR---LEEKIREIEIEVKD----ID 496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2683 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVtKENKGLTAQIQSFGRSMsslqnsrdhaneELDEL 2762
Cdd:PRK01156   497 EKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINEL-KDKHDKYEEIKNRYKSL------------KLEDL 563

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2763 KRKYDASLKELAQLKEQGLLN-----RERDALLSETAFSMNSTEENsLSHLEKLNQQLLSKDEQLLHLssqLEDSYNQVQ 2837
Cdd:PRK01156   564 DSKRTSWLNALAVISLIDIETnrsrsNEIKKQLNDLESRLQEIEIG-FPDDKSYIDKSIREIENEANN---LNNKYNEIQ 639

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2838 SFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT 2917
Cdd:PRK01156   640 ENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRIN 719


                   ..
gi 1483569506 2918 EL 2919
Cdd:PRK01156   720 DI 721
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 694-1485 3.95e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 3.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  694 LKSQILELELNFHKAQEIYEKNLDEkAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQ 773
Cdd:TIGR00606  222 IRDQITSKEAQLESSREIVKSYENE-LDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTD 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  774 LEMNLAEAERQRRLDYESQTAHDnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV- 852
Cdd:TIGR00606  301 EQLNDLYHNHQRTVREKERELVD--CQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLe 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  853 LEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQtieekdQQVTEISFSMTEKMVQLNEEKFSLGVE 932
Cdd:TIGR00606  379 LDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQ------EQADEIRDEKKGLGRTIELKKEILEKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  933 IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQ--NYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINR-KE 1009
Cdd:TIGR00606  453 QEELKFVIKELQQLEGSSDRILELDQELRKAERElsKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHhTT 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1010 LLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY------LKQTISEKEVELQHIRK 1083
Cdd:TIGR00606  533 TRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTrdrlakLNKELASLEQNKNHINN 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1084 DLEEKLAAEEQFQALVKQMNQTlQDKTNQIDLLQAEIsENQAIIQKLITSNTDASDGDSVALVKETVVISPPC------T 1157
Cdd:TIGR00606  613 ELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEI-EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCqrvfqtE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1158 GSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQ 1237
Cdd:TIGR00606  691 AELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQ 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1238 LRQLqiqvrESIDGKLPSTdqqESCSSTPGLEEPLFKATEQHHTQpvlesnlcpdWPSHSEDASALQGGTSVAQIKAQLK 1317
Cdd:TIGR00606  771 ETLL-----GTIMPEEESA---KVCLTDVTIMERFQMELKDVERK----------IAQQAAKLQGSDLDRTVQQVNQEKQ 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1318 EIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE-LQ 1396
Cdd:TIGR00606  833 EKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEqDS 912

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1397 PKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE----IIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1472
Cdd:TIGR00606  913 PLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKvkniHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKH 992

                          810
                   ....*....|...
gi 1483569506 1473 PEEIGEESRAKQQ 1485
Cdd:TIGR00606  993 QEKINEDMRLMRQ 1005
PRK09039 PRK09039
peptidoglycan -binding protein;
2698-2832 4.01e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.26  E-value: 4.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2698 IMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK 2777
Cdd:PRK09039    43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELA 122

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1483569506 2778 EQglLNRERDalLSETAfsmnsteensLSHLEKLNQQLLSKDEQLLHLSSQLEDS 2832
Cdd:PRK09039   123 QE--LDSEKQ--VSARA----------LAQVELLNQQIAALRRQLAALEAALDAS 163
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1385-1566 4.15e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 4.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1385 QIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQV 1464
Cdd:COG1579      5 DLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIK----RLELEIEEVEARIKKYEE 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1465 ELcEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTvlg 1544
Cdd:COG1579     81 QL-GNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA--- 156

                          170       180
                   ....*....|....*....|..
gi 1483569506 1545 RLALLQEERDKLITEMDRSLLE 1566
Cdd:COG1579    157 ELEELEAEREELAAKIPPELLA 178
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1300-1493 4.53e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1300 ASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLeieslktvsheaevhaeslqQKL 1379
Cdd:COG4913    281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG--------------------DRL 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1380 ESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDER 1458
Cdd:COG4913    341 EQLEREIERLErELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1483569506 1459 IKQLQVELCEMKQKPEEIGEES-RAKQQIQRKLQAA 1493
Cdd:COG4913    421 LRELEAEIASLERRKSNIPARLlALRDALAEALGLD 456
PTZ00121 PTZ00121
MAEBL; Provisional
 1976-2515 4.77e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 4.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1976 EKQQLVKEKTKVESEIRKEylEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQT 2055
Cdd:PTZ00121  1221 EDAKKAEAVKKAEEAKKDA--EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKA 1298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2056 ESQKDLEITK----------ENLAQAVEHRKKAQA--ELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ 2123
Cdd:PTZ00121  1299 EEKKKADEAKkkaeeakkadEAKKKAEEAKKKADAakKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2124 KDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEiqvTLNKKDKEVQQLQEnLDSTVTQLAAFTKSMSSLQ 2203
Cdd:PTZ00121  1379 KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD---EAKKKAEEKKKADE-AKKKAEEAKKADEAKKKAE 1454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2204 DDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDncsvLKDQLRQMSIHMEELKiniSRLEHDKQIWESKAQTEVQLQQKV 2283
Cdd:PTZ00121  1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE----AKKKAEEAKKKADEAK---KAAEAKKKADEAKKAEEAKKADEA 1527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2284 CDTLQGENKELLSQLEETRhlyhsSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQ 2363
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKK-----KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE 1602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2364 LETDLQASReltSRLHEEINMKEQKIisllsGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2443
Cdd:PTZ00121  1603 EEKKMKAEE---AKKAEEAKIKAEEL-----KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1483569506 2444 NQLMETLKT--IKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2515
Cdd:PTZ00121  1675 KKAEEAKKAeeDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
281-538 4.93e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 4.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  281 DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSfhnlqeemhHLLEQFEQAGQA 360
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLS---------ELESQLAEARAE 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  361 QAELESRYSALEQKHKAEMEEKTSHILS--LQKTGQELQSAcDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKE 438
Cdd:COG3206    235 LAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAEL-EAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQR 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  439 ISQFLnrlplqqhetasqtsfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEklSSQITLLEA 518
Cdd:COG3206    314 ILASL---------------------EAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVE--VARELYESL 370

                          250       260
                   ....*....|....*....|....
gi 1483569506  519 QNRTGEAD----REVSEISIVDIA 538
Cdd:COG3206    371 LQRLEEARlaeaLTVGNVRVIDPA 394
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2589-2999 4.96e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 4.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2589 EDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhaqlkvKEEEVHRLSALFSSSQKRIAELEEELv 2668
Cdd:COG4717     84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLE--------------KLLQLLPLYQELEALEAELAELPERL- 148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2669 cvqkeaakkvgeieDKLKKELKHLHHdagiMRNETETAEERVAELARDLVEMEQKLLMVTKEnkgltaQIQSFGRSMSSL 2748
Cdd:COG4717    149 --------------EELEERLEELRE----LEEELEELEAELAELQEELEELLEQLSLATEE------ELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2749 QNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQ 2828
Cdd:COG4717    205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLG 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2829 LEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSE--EGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQ 2906
Cdd:COG4717    285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEEleELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2907 QQYLQINQE----------ITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYL 2976
Cdd:COG4717    365 LEELEQEIAallaeagvedEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEEL 444

                          410       420
                   ....*....|....*....|....
gi 1483569506 2977 MA-ISDKDQQLSHLQNLIRELRSS 2999
Cdd:COG4717    445 EEeLEELREELAELEAELEQLEED 468
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1308-1508 5.19e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 5.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1308 SVAQIKAQLKEIEAEKVELELKVSS--TTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1385
Cdd:COG3206    176 ALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1386 IAGLEHLRELQPKLDELQKLISKKEEdvsyLSGQLSEKEAALTKIQTEIIEQEDLIKA----LHTQLEMQAKEHDERIKQ 1461
Cdd:COG3206    256 LPELLQSPVIQQLRAQLAELEAELAE----LSARYTPNHPDVIALRAQIAALRAQLQQeaqrILASLEAELEALQAREAS 331

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1483569506 1462 LQVELCEMKQKPEEIGEESRAKQQIQRKLQAA------LISRKEALKENKSLQ 1508
Cdd:COG3206    332 LQAQLAQLEARLAELPELEAELRRLEREVEVArelyesLLQRLEEARLAEALT 384
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1456-1708 5.25e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 5.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1456 DERIKQLQ----VELCEMKQkpEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGT-----IERLTKSLA 1526
Cdd:PRK05771    19 DEVLEALHelgvVHIEDLKE--ELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKsleelIKDVEEELE 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1527 DVESQVSAQNKEkdtvlgrLALLQEERDKLITEMDR-SLLENQSLS----SSCESLKLALEGLTEDKEKLVKEIESLKSS 1601
Cdd:PRK05771    97 KIEKEIKELEEE-------ISELENEIKELEQEIERlEPWGNFDLDlsllLGFKYVSVFVGTVPEDKLEELKLESDVENV 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1602 KIAESTEwqEK-------HKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrstEANKKETEKQLqeaeq 1674
Cdd:PRK05771   170 EYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL-------EEIEKERESLL----- 235

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1483569506 1675 emeemkEKMRKFAKSKQQKILELEE--ENDRLRAEV 1708
Cdd:PRK05771   236 ------EELKELAKKYLEELLALYEylEIELERAEA 265
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
816-1219 5.53e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 5.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  816 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELS--QALSQKELEITKMDQLLLEKKRD 893
Cdd:PRK03918   232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELRE 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  894 VETLQQTIEEKDQQVTEisfsmteKMVQLNEEKfslgVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSP 973
Cdd:PRK03918   312 IEKRLSRLEEEINGIEE-------RIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKR 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  974 AGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKdESKKEIPLSETERGEVEEDKENKEYse 1053
Cdd:PRK03918   381 LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK-KAKGKCPVCGRELTEEHRKELLEEY-- 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1054 kcvTSKCQEIEIYLKqTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQ--TLQDKTNQIDL--LQAEISENQAIIQK 1129
Cdd:PRK03918   458 ---TAELKRIEKELK-EIEEKERKLRKELRELEKVLKKESELIKLKELAEQlkELEEKLKKYNLeeLEKKAEEYEKLKEK 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1130 LITSntdasDGDSVALVKETvvisppctgssehwkpeleEKILALEKEKEQLQKKLQEALTSRKAILKKAQEK----ERH 1205
Cdd:PRK03918   534 LIKL-----KGEIKSLKKEL-------------------EKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEE 589

                          410
                   ....*....|....
gi 1483569506 1206 LREELKQQKDDYNR 1219
Cdd:PRK03918   590 LEERLKELEPFYNE 603
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2225-2985 5.82e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.73  E-value: 5.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2225 QSKEEEIRLKEDNCSVLKDQLRQMsihmEELKINISRLEHDKQIWESkaqTEVQLQQKVCDTLQGENKELLSQLEETRHL 2304
Cdd:TIGR00606  234 ESSREIVKSYENELDPLKNRLKEI----EHNLSKIMKLDNEIKALKS---RKKQMEKDNSELELKMEKVFQGTDEQLNDL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2305 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEgiIRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEEINM 2384
Cdd:TIGR00606  307 YHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL--VEQGRLQLQADRHQEHIRARDSLI---QSLATRLELDG 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2385 KEQKIISllsgkEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL 2464
Cdd:TIGR00606  382 FERGPFS-----ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2465 DSFVKSMSSLQNDRDRIVGDYQQL--EERHLSIiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE----- 2537
Cdd:TIGR00606  457 KFVIKELQQLEGSSDRILELDQELrkAERELSK-AEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtttrt 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2538 ----LIQYREDLNQVITIKDSQQKQLLEVQL---QQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIE 2610
Cdd:TIGR00606  536 qmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2611 SLKVSISQLTRQV----TALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKeAAKKVGEIEDKLK 2686
Cdd:TIGR00606  616 SKEEQLSSYEDKLfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCP-VCQRVFQTEAELQ 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2687 KELKHLHHDAGIMRNETETAEERVAELARD------LVEMEQKLL-MVTKENKGLTAQIQSFGRSMSSLQNSRDHANEEL 2759
Cdd:TIGR00606  695 EFISDLQSKLRLAPDKLKSTESELKKKEKRrdemlgLAPGRQSIIdLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2760 D------ELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEEnslshLEKLNQQLLSKDEQLLHLSSQLEDSY 2833
Cdd:TIGR00606  775 GtimpeeESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRT-----VQQVNQEKQEKQHELDTVVSKIELNR 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2834 NQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ-I 2912
Cdd:TIGR00606  850 KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEElI 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2913 NQEITELHPLKAQLQEYQDKTKA--------FQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQ 2984
Cdd:TIGR00606  930 SSKETSNKKAQDKVNDIKEKVKNihgymkdiENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDT 1009


                   .
gi 1483569506 2985 Q 2985
Cdd:TIGR00606 1010 Q 1010
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2520-2722 5.89e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 5.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2520 LRSHMDDLNSENAKLDAELIQYREDLNQvitikdsqqkqlLEVQLQQNKElENKYAKLEEKLKESEEANEDLRRSFNALQ 2599
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELEE------------AEAALEEFRQ-KNGLVDLSEEAKLLLQQLSELESQLAEAR 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2600 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVG 2679
Cdd:COG3206    233 AELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1483569506 2680 EIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2722
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
46 PHA02562
endonuclease subunit; Provisional
 2543-2779 6.01e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 6.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2543 EDL--NQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQD----LSKEIESLKVSI 2616
Cdd:PHA02562   157 EDLldISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKTIKAEI 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2617 SQLTRQVTALQEEGtlGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVC------------VQKEAAKKVGEIEDK 2684
Cdd:PHA02562   237 EELTDELLNLVMDI--EDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCptctqqisegpdRITKIKDKLKELQHS 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2685 LKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQsfgrsmsSLQNSRDHANEELDELKR 2764
Cdd:PHA02562   315 LEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQD 386

                          250
                   ....*....|....*
gi 1483569506 2765 KYDASLKELAQLKEQ 2779
Cdd:PHA02562   387 ELDKIVKTKSELVKE 401
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 699-1413 6.45e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.73  E-value: 6.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  699 LELELNFHKAQEIYEKnLDEKAKEISNLNQLIEEFKKNADNNSSAFTA----LSEERDQLLSQVKElSMVTELRAQVKQL 774
Cdd:TIGR01612 1005 LKANLGKNKENMLYHQ-FDEKEKATNDIEQKIEDANKNIPNIEIAIHTsiynIIDEIEKEIGKNIE-LLNKEILEEAEIN 1082

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  775 EMNLAE-AERQRRLDYESQTAHDNL-LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV 852
Cdd:TIGR01612 1083 ITNFNEiKEKLKHYNFDDFGKEENIkYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA 1162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  853 LEGaERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRdVETLQQTIEEkdqqVTEISFSMTEKM-----VQLNEEKF 927
Cdd:TIGR01612 1163 ISN-DDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAE-IEKDKTSLEE----VKGINLSYGKNLgklflEKIDEEKK 1236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  928 SLGVEIKTLKEQLNLLsraEEAKKEQVEEDNEVSSGLKQNyDEMSPAgQISKEELQHEFDLLKKENEQRKRKLQAALinr 1007
Cdd:TIGR01612 1237 KSEHMIKAMEAYIEDL---DEIKEKSPEIENEMGIEMDIK-AEMETF-NISHDDDKDHHIISKKHDENISDIREKSL--- 1308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1008 kELLQRVSRlEEELANLKDESKKEIplsetergeVEEDKENkeysekcvtskcQEIEIYLKQTISEKEV-ELQHIRKDLE 1086
Cdd:TIGR01612 1309 -KIIEDFSE-ESDINDIKKELQKNL---------LDAQKHN------------SDINLYLNEIANIYNIlKLNKIKKIID 1365

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1087 EKlaaeEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAI--IQKLITSNTDASDGDSV---ALVKETVVISPPcTGSSE 1161
Cdd:TIGR01612 1366 EV----KEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLeeCKSKIESTLDDKDIDECikkIKELKNHILSEE-SNIDT 1440

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1162 HWK--PELEEKILALEKEKEQLQKKLQEALTSRKailKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLR 1239
Cdd:TIGR01612 1441 YFKnaDENNENVLLLFKNIEMADNKSQHILKIKK---DNATNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFE 1517

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1240 QLQIQVRESIDgKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLES-------NLCPDWPSHSEDASALQGGTSVAQI 1312
Cdd:TIGR01612 1518 QYKKDVTELLN-KYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAekseqkiKEIKKEKFRIEDDAAKNDKSNKAAI 1596

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1313 KAQLKEIEAEKVELELkvssttSELTKKSEEVFQLQEQINKQ--GLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE 1390
Cdd:TIGR01612 1597 DIQLSLENFENKFLKI------SDIKKKINDCLKETESIEKKisSFSIDSQDTELKENGDNLNSLQEFLESLKDQKKNIE 1670

                          730       740
                   ....*....|....*....|...
gi 1483569506 1391 hlrELQPKLDELQKLISKKEEDV 1413
Cdd:TIGR01612 1671 ---DKKKELDELDSEIEKIEIDV 1690
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 836-1050 6.65e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 6.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  836 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM 915
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  916 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNydemspagQISKEELQHEFDLLKKENE 994
Cdd:COG3883     96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKADKAELEAK--------KAELEAKLAELEALKAELE 167

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1483569506  995 QRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1050
Cdd:COG3883    168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1063-1242 6.75e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 6.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1063 IEIYLKQTISEK-----------EVELQHIRKDLEEKLAAEEQFQA---------LVKQMNQTLQDKTNQIDLLQAEISE 1122
Cdd:COG3206    158 AEAYLEQNLELRreearkaleflEEQLPELRKELEEAEAALEEFRQknglvdlseEAKLLLQQLSELESQLAEARAELAE 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1123 NQAIIQKLitSNTDASDGDSVALVKETVVISppctgssehwkpELEEKILALEKEKEQ--------------LQKKLQEA 1188
Cdd:COG3206    238 AEARLAAL--RAQLGSGPDALPELLQSPVIQ------------QLRAQLAELEAELAElsarytpnhpdviaLRAQIAAL 303

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1483569506 1189 LTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1242
Cdd:COG3206    304 RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2042-2211 6.99e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 41.52  E-value: 6.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2042 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2117
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2118 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2174
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1483569506 2175 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2211
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
46 PHA02562
endonuclease subunit; Provisional
 2436-2681 7.12e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 7.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2436 NKKAVDKTNQLMETLkTIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2515
Cdd:PHA02562   172 NKDKIRELNQQIQTL-DMKIDHIQQ--QIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVM 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2516 EIRGLRSHMDDLNSENAKLDAELIQYREDlnqvitIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSF 2595
Cdd:PHA02562   249 DIEDPSAALNKLNTAAAKIKSKIEQFQKV------IKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAI 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2596 NALQE---EKQDLSKEIESLKVSISQLTRQVTAlqeegtlglYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK 2672
Cdd:PHA02562   323 DELEEimdEFNEQSKKLLELKNKISTNKQSLIT---------LVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVK 393


                   ....*....
gi 1483569506 2673 EAAKKVGEI 2681
Cdd:PHA02562   394 TKSELVKEK 402
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 247-926 7.50e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.34  E-value: 7.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  247 TQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNtlrntvetereesKILL 326
Cdd:TIGR00606  409 TAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSD-------------RILE 475

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  327 EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELqSACDALKDQ 406
Cdd:TIGR00606  476 LDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKM-DKDEQIRKI 554

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  407 NSKLLQDKNEQAVQSAQTiQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEE---------NIAS 477
Cdd:TIGR00606  555 KSRHSDELTSLLGYFPNK-KQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQlssyedklfDVCG 633

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  478 LQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQN--------RTGEADREVSEIsIVDIANKRSSSAEEsg 549
Cdd:TIGR00606  634 SQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENqsccpvcqRVFQTEAELQEF-ISDLQSKLRLAPDK-- 710

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  550 QDVLENTFSQKHKELSVLLL-------EMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLED 622
Cdd:TIGR00606  711 LKSTESELKKKEKRRDEMLGlapgrqsIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTD 790

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  623 TGqdfpLMPNEESSLPAVEKEqasTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIG--------------QCHQ 688
Cdd:TIGR00606  791 VT----IMERFQMELKDVERK---IAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIelnrkliqdqqeqiQHLK 863

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  689 DELERLKSQILELELNFHKAQEiYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELR 768
Cdd:TIGR00606  864 SKTNELKSEKLQIGTNLQRRQQ-FEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK 942

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  769 AQ---------------------------VKQLEMNLA-----------------EAERQRRLDYESQTAHDNLLTEQIH 804
Cdd:TIGR00606  943 VNdikekvknihgymkdienkiqdgkddyLKQKETELNtvnaqleecekhqekinEDMRLMRQDIDTQKIQERWLQDNLT 1022

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  805 SLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKmd 884
Cdd:TIGR00606 1023 LRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAE-- 1100

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1483569506  885 qlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEK 926
Cdd:TIGR00606 1101 ----EKYREMMIVMRTTELVNKDLDIYYKTLDQAIMKFHSMK 1138
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 2288-2936 7.56e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.26  E-value: 7.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2288 QGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKcKEQKGNLEGIIRQQEADIQNSKFSYEQLETD 2367
Cdd:TIGR00618  238 TQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQER-INRARKAAPLAAHIKAVTQIEQQAQRIHTEL 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2368 LQASRELTSRLHEEIN-MKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKtnQL 2446
Cdd:TIGR00618  317 QSKMRSRAKLLMKRAAhVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLT--QK 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2447 METLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDyQQLEERHLSIileKDQLIQEAAAENNKLKEEIRGLRSHMDD 2526
Cdd:TIGR00618  395 LQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQ-QELQQRYAEL---CAAAITCTAQCEKLEKIHLQESAQSLKE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2527 LNSENAKLDAELIQYREDLNQVITIKDSQQKQL---------LEVQLQQNKELE---NKYAKLEEKLKESEEANEDLRRS 2594
Cdd:TIGR00618  471 REQQLQTKEQIHLQETRKKAVVLARLLELQEEPcplcgscihPNPARQDIDNPGpltRRMQRGEQTYAQLETSEEDVYHQ 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2595 FNALQEEKQDLSKEIESLKVSISQLTRQVTALQE--EGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK 2672
Cdd:TIGR00618  551 LTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEdiPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDV 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2673 EAAKkvGEIEDKLKKELKHLHhdagimRNETETAEERVAELARDLVEMEQKLLmvtKENKGLTAQIQSFGRSMSSLQNSR 2752
Cdd:TIGR00618  631 RLHL--QQCSQELALKLTALH------ALQLTLTQERVREHALSIRVLPKELL---ASRQLALQKMQSEKEQLTYWKEML 699

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2753 DHANEELDELKRKYDASLKELAQLKE----QGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQ 2828
Cdd:TIGR00618  700 AQCQTLLRELETHIEEYDREFNEIENasssLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2829 LEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEG-KQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQ 2907
Cdd:TIGR00618  780 LSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDiLNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSK 859

                          650       660
                   ....*....|....*....|....*....
gi 1483569506 2908 QYLQINQEITELHPLKAQLQEYQDKTKAF 2936
Cdd:TIGR00618  860 QLAQLTQEQAKIIQLSDKLNGINQIKIQF 888
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1845-1998 8.09e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.68  E-value: 8.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1845 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKE------ 1918
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1919 ---TAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1995
Cdd:COG1579     97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                   ...
gi 1483569506 1996 LEK 1998
Cdd:COG1579    177 LAL 179
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 165-513 8.11e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 42.25  E-value: 8.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  165 AQLTQAQA--EQPAQSSTEMEEFVMMKQQLQEKeefISTLQAQLSQTQAEQAAQlssmQQVVREKD---ARFETQVRLHE 239
Cdd:COG3096    316 EELSARESdlEQDYQAASDHLNLVQTALRQQEK---IERYQEDLEELTERLEEQ----EEVVEEAAeqlAEAEARLEAAE 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  240 DELLQLVTQ-ADVetemQQKLRVLQRKLEEHEESL--VGRAQVV-DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTV 315
Cdd:COG3096    389 EEVDSLKSQlADY----QQALDVQQTRAIQYQQAVqaLEKARALcGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKL 464

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  316 E------TEREESKILLEKMELEVaERKLSFHNLQE------EMHHLLEQFEQAGQAQAELESRysaLEQKHKA-----E 378
Cdd:COG3096    465 SvadaarRQFEKAYELVCKIAGEV-ERSQAWQTAREllrryrSQQALAQRLQQLRAQLAELEQR---LRQQQNAerlleE 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  379 MEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSK------EISQFLNRLPLQQHE 452
Cdd:COG3096    541 FCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAArapawlAAQDALERLREQSGE 620

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1483569506  453 TAsqtsfpdvynEGTQAVTEEniaslqkRVVELENEKGAlllsSIELEELKAENEKLSSQI 513
Cdd:COG3096    621 AL----------ADSQEVTAA-------MQQLLEREREA----TVERDELAARKQALESQI 660
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1852-2388 8.19e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 8.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1852 ERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERL 1931
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 1932 MNQLAELNGsignycqdvtdAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSH 2011
Cdd:pfam01576   85 EEEEERSQQ-----------LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2012 AKELQEL-------LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAS 2084
Cdd:pfam01576  154 RKLLEERiseftsnLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAE 233

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2085 FKVLLDDTQSEAARVLA---DNLKLKKELQSNKESVKSQMKQKDEDLERRlEQAEEKHLKEKKNMQEKLDALRREKVHLE 2161
Cdd:pfam01576  234 LRAQLAKKEEELQAALArleEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEALKTELEDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2162 ETIGEIQVTLNKKDKEVQQLQENLDSTV----TQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEE-------E 2230
Cdd:pfam01576  313 DTTAAQQELRSKREQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenaelqaE 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2231 IRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWE---SKAQTEVQ-------LQQKVCDTLQGENKELLSQLEE 2300
Cdd:pfam01576  393 LRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAeklSKLQSELEsvssllnEAEGKNIKLSKDVSSLESQLQD 472

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2301 TRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE 2380
Cdd:pfam01576  473 TQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQR 552


                   ....*...
gi 1483569506 2381 EINMKEQK 2388
Cdd:pfam01576  553 ELEALTQQ 560
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
152-586 8.98e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 8.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  152 KLQEKEELISTLQAQLTQAQAEQPAQSSTEmEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQA-----AQLSSMQQVVRE 226
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELEELE-EELEELEAELEELREELEKLEKLLQLLPLYQElealeAELAELPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  227 KDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVD----LLQQELTAAEQRNQILSQQLQ 302
Cdd:COG4717    151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQqrlaELEEELEEAQEELEELEEELE 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  303 QMEAEHntlrntvETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEK 382
Cdd:COG4717    231 QLENEL-------EAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKE 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  383 TSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQflnrLPLQQHETASQTSFpdv 462
Cdd:COG4717    304 AEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE----LQLEELEQEIAALL--- 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  463 ynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEIS--IVDIANK 540
Cdd:COG4717    377 --AEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEeeLEELREE 454

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 1483569506  541 RSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQ 586
Cdd:COG4717    455 LAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALE 500
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2476-2762 9.03e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 9.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2476 NDRDRIVGDY-------QQLEErhlsiileKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdAELIQYREDLNQV 2548
Cdd:COG4913    593 DDRRRIRSRYvlgfdnrAKLAA--------LEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV 663

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2549 itikDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2626
Cdd:COG4913    664 ----ASAEREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506 2627 QEEGTLGLyHAQLkvkeeEVHRLSALFSSSQKRIAE-LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET 2705
Cdd:COG4913    740 EDLARLEL-RALL-----EERFAAALGDAVERELREnLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLES 813

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1483569506 2706 AEERVAELAR----DLVEMEQKLLMVTKENkgltaQIQSFGRSMSSLQNSRDHANEELDEL 2762
Cdd:COG4913    814 LPEYLALLDRleedGLPEYEERFKELLNEN-----SIEFVADLLSKLRRAIREIKERIDPL 869
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
816-1006 9.74e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 9.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  816 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN--KESEVLEGAERVRHISSKVEELSQALSQKELEITKmdqlLLEKKRD 893
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDD 686

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  894 VETLQQTIEEKDQQVTEisfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEE-DNEVSSGLKQNYDEMS 972
Cdd:COG4913    687 LAALEEQLEELEAELEE-----------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLARLELRALLEERF 755

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1483569506  973 PAGQISK--EELQHEFDLLKKENEQRKRKLQAALIN 1006
Cdd:COG4913    756 AAALGDAveRELRENLEERIDALRARLNRAEEELER 791
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 248-358 9.96e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.86  E-value: 9.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1483569506  248 QADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLR-NTVETEREeskill 326
Cdd:PRK11448   140 PENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQeKAAETSQE------ 213

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1483569506  327 EKMEL-EVAERKLSFHNLQEEMHHLL--EQFEQAG 358
Cdd:PRK11448   214 RKQKRkEITDQAAKRLELSEEETRILidQQLRKAG 248
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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