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Conserved domains on  [gi|1402371420|ref|NP_001351307|]
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tetratricopeptide repeat protein 8 isoform 3 [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 1915945)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
dermokine super family cl42387
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 1-45 5.53e-23

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


The actual alignment was detected with superfamily member cd21341:

Pssm-ID: 455732 [Multi-domain]  Cd Length: 139  Bit Score: 93.52  E-value: 5.53e-23
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1402371420   1 MEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSR 45
Cdd:cd21341    95 SRQALRTPRRAGTARPVTSASGRFVRLGTASMLSGPDGPFINVSR 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 98-328 3.42e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.80  E-value: 3.42e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  98 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSS 176
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 177 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLA 256
Cdd:COG2956    95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1402371420 257 ENeeeAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 328
Cdd:COG2956   175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243
 
Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 1-45 5.53e-23

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 93.52  E-value: 5.53e-23
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1402371420   1 MEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSR 45
Cdd:cd21341    95 SRQALRTPRRAGTARPVTSASGRFVRLGTASMLSGPDGPFINVSR 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 98-328 3.42e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.80  E-value: 3.42e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  98 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSS 176
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 177 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLA 256
Cdd:COG2956    95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1402371420 257 ENeeeAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 328
Cdd:COG2956   175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 96-364 1.82e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 56.25  E-value: 1.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  96 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQpvtalnlFKQGLDKFPGEvtllcgiariyeEMNNS 174
Cdd:TIGR02917  61 LLGKIYLALGDYAAAEKELRKALSLGyPKNQVLPLLARAYLLQGK-------FQQVLDELPGK------------TLLDD 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 175 SSAAEYYkevlkqdnthveaiACIGSNHFYSDQPEVALRFYRRLLQMGVYNcqLFNNLGLccfyAQ------QYDMTLTS 248
Cdd:TIGR02917 122 EGAAELL--------------ALRGLAYLGLGQLELAQKSYEQALAIDPRS--LYAKLGL----AQlalaenRFDEARAL 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 249 FERALSLaenEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 328
Cdd:TIGR02917 182 IDEVLTA---DPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAP 258

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1402371420 329 HMYEPHFNFATVSDKIGDLQRSYVAAQKSEVAFPEH 364
Cdd:TIGR02917 259 NSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEY 294
TPR_12 pfam13424
Tetratricopeptide repeat;
226-290 6.69e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.14  E-value: 6.69e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 226 CQLFNNLGLCCFYAQQYDMTLTSFERALSLAENE-----EEAADVWYNLGHIAVGIGDTNLAHQCFRLAL 290
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhPLTATTLLNLGRLYLELGRYEEALELLERAL 72
LPA1 PLN03098
LOW PSII ACCUMULATION1; Provisional
 231-290 2.92e-03

LOW PSII ACCUMULATION1; Provisional


Pssm-ID: 215573 [Multi-domain]  Cd Length: 453  Bit Score: 39.49  E-value: 2.92e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 231 NLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLAL 290
Cdd:PLN03098   80 NLGLSLFSKGRVKDALAQFETALELNPNPDEAQAAYYNKACCHAYREEGKKAADCLRTAL 139
 
Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 1-45 5.53e-23

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 93.52  E-value: 5.53e-23
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 1402371420   1 MEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSR 45
Cdd:cd21341    95 SRQALRTPRRAGTARPVTSASGRFVRLGTASMLSGPDGPFINVSR 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 98-328 3.42e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.80  E-value: 3.42e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  98 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSS 176
Cdd:COG2956    15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 177 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLA 256
Cdd:COG2956    95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1402371420 257 ENeeeAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 328
Cdd:COG2956   175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP 243
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
155-323 5.19e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 88.14  E-value: 5.19e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 155 PGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGL 234
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 235 CCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVE 314
Cdd:COG0457    85 ALQALGRYEEALEDYDKALELDPDD---AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161


                  ....*....
gi 1402371420 315 QARALLQTA 323
Cdd:COG0457   162 EALELLEKL 170
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 127-356 6.42e-20

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 88.63  E-value: 6.42e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 127 FLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSD 206
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 207 QPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNLAHQCF 286
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN---AHAYCELAELYLEQGDYDEAIEAL 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 287 RLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQK 356
Cdd:COG2956   168 EKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRK 237
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
185-360 2.28e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.82  E-value: 2.28e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 185 LKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLaenEEEAAD 264
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL---DPDDAE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 265 VWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPHMYEPHFNFATVSDKI 344
Cdd:COG0457    78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157

                         170
                  ....*....|....*.
gi 1402371420 345 GDLQRSYVAAQKSEVA 360
Cdd:COG0457   158 GRYEEALELLEKLEAA 173
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
122-332 3.36e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.44  E-value: 3.36e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 122 EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSN 201
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 202 HFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHIAVGIGDTNL 281
Cdd:COG0457    86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADA---LYNLGIALEKLGRYEE 162

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1402371420 282 AHQCFRLALvHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPHMYE 332
Cdd:COG0457   163 ALELLEKLE-AAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLA 212
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 96-323 2.81e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 78.23  E-value: 2.81e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  96 QIGKCYYRLGMYREAEKQFKSALKQQEMVDTFLY-LAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNS 174
Cdd:COG2956    47 ALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLeLAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDW 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 175 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALs 254
Cdd:COG2956   127 EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL- 205

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1402371420 255 laENEEEAADVWYNLGHIAVGIGDTNLAHQCFRlALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTA 323
Cdd:COG2956   206 --EQDPDYLPALPRLAELYEKLGDPEEALELLR-KALELDPSDDLLLALADLLERKEGLEAALALLERQ 271
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 95-293 3.61e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 77.85  E-value: 3.61e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  95 VQIGKCYYRLGMYREAEKQFKSALKQQEM-VDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNN 173
Cdd:COG2956    80 LELAQDYLKAGLLDRAEELLEKLLELDPDdAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGD 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 174 SSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERAL 253
Cdd:COG2956   160 YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAL 239

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1402371420 254 SLAENeeeaADVWYNLGHIAVGIGDTNLAHQCFRLALVHN 293
Cdd:COG2956   240 ELDPS----DDLLLALADLLERKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
97-321 4.14e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.97  E-value: 4.14e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  97 IGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSS 175
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKALElDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 176 SAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSL 255
Cdd:COG0457    94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1402371420 256 AENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQ 321
Cdd:COG0457   174 ALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALA 239
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 239-371 2.72e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 77.34  E-value: 2.72e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 239 AQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARA 318
Cdd:COG3914    91 LGRYEEALALYRRALALNPDN---AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIA 167

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1402371420 319 LLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEVAFPEHVDTQHLI 371
Cdd:COG3914   168 ALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
219-369 5.11e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.89  E-value: 5.11e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 219 LQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAE 298
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEA---LYNLGLAYLRLGRYEEALADYEQALELDPDDAE 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1402371420 299 AYNNLAVLEMRKGHVEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEVAFPEHVDTQH 369
Cdd:COG0457    78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALY 148
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 96-221 2.60e-13

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 66.75  E-value: 2.60e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  96 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNS 174
Cdd:COG4783     9 ALAQALLLAGDYDEAEALLEKALELDpDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDY 88

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1402371420 175 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQM 221
Cdd:COG4783    89 DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 160-327 1.30e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 69.25  E-value: 1.30e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 160 LLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYA 239
Cdd:COG3914    80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 240 QQYDMTLTSFERALSLAENEEEAadvWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARAL 319
Cdd:COG3914   160 GRLEEAIAALRRALELDPDNAEA---LNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRF 236


                  ....*...
gi 1402371420 320 LQTASSLA 327
Cdd:COG3914   237 EELLAALA 244
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 121-259 2.25e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.06  E-value: 2.25e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 121 QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGS 200
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1402371420 201 NHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENE 259
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 164-328 5.29e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.90  E-value: 5.29e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 164 IARIYEEMNNSSSAAEYYKEVLKQDNTHVEAiacigsnhfysdqpevalrfyrrllqmgvyncqlFNNLGLCCFYAQQYD 243
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEA----------------------------------FALLGEILLQLGDLD 55

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 244 MTLTSFERALSLAENEEEAadvWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTA 323
Cdd:COG4783    56 EAIVLLHEALELDPDEPEA---RLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKA 132


                  ....*
gi 1402371420 324 SSLAP 328
Cdd:COG4783   133 LELDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
96-220 3.51e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 62.72  E-value: 3.51e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  96 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNS 174
Cdd:COG0457    47 NLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRY 126

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1402371420 175 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQ 220
Cdd:COG0457   127 DEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEA 172
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 232-364 4.40e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.21  E-value: 4.40e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 232 LGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKG 311
Cdd:COG4783    10 LAQALLLAGDYDEAEALLEKALELDPDNPEA---FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1402371420 312 HVEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEVAFPEH 364
Cdd:COG4783    87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 109-221 1.98e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 58.09  E-value: 1.98e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 109 EAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQ 187
Cdd:COG4235     1 EAIARLRQALAANpNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1402371420 188 DNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQM 221
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 263-376 2.35e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.01  E-value: 2.35e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 263 ADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPHMYEPHFNFATVSD 342
Cdd:COG4235    17 AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1402371420 343 KIGDLQRSYVAAQKSEVAFPEHVDTQHLIKQLKQ 376
Cdd:COG4235    97 QQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
239-332 3.59e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 53.64  E-value: 3.59e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 239 AQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNLAHQcFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARA 318
Cdd:COG3063     5 LGDLEEAEEYYEKALELDPDN---ADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|....
gi 1402371420 319 LLQTASSLAPHMYE 332
Cdd:COG3063    81 YLERALELDPSALR 94
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 260-376 7.65e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.66  E-value: 7.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 260 EEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPHMYEPHFNFAT 339
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1402371420 340 VSDKIGDLQRSYVAAQKSEVAFPEHVDTQHLIKQLKQ 376
Cdd:COG4783    81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYR 117
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 97-221 9.81e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.93  E-value: 9.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  97 IGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSS 175
Cdd:COG3914   118 LGNLLLALGRLEEALAALRRALALNpDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLE 197

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1402371420 176 SAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQM 221
Cdd:COG3914   198 EAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAAL 243
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 238-348 1.36e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.54  E-value: 1.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 238 YAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQAR 317
Cdd:COG3914    53 EAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEAL 132

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1402371420 318 ALLQTASSLAPHMYEPHFNFATVSDKIGDLQ 348
Cdd:COG3914   133 AALRRALALNPDFAEAYLNLGEALRRLGRLE 163
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 143-265 1.38e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 52.70  E-value: 1.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 143 ALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMG 222
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1402371420 223 VYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADV 265
Cdd:COG4235    82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLL 124
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 234-328 1.64e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 53.43  E-value: 1.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 234 LCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHV 313
Cdd:COG5010    62 NLYNKLGDFEESLALLEQALQLDPNN---PELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQD 138

                          90
                  ....*....|....*
gi 1402371420 314 EQARALLQTASSLAP 328
Cdd:COG5010   139 DEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 96-364 1.82e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 56.25  E-value: 1.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  96 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQpvtalnlFKQGLDKFPGEvtllcgiariyeEMNNS 174
Cdd:TIGR02917  61 LLGKIYLALGDYAAAEKELRKALSLGyPKNQVLPLLARAYLLQGK-------FQQVLDELPGK------------TLLDD 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 175 SSAAEYYkevlkqdnthveaiACIGSNHFYSDQPEVALRFYRRLLQMGVYNcqLFNNLGLccfyAQ------QYDMTLTS 248
Cdd:TIGR02917 122 EGAAELL--------------ALRGLAYLGLGQLELAQKSYEQALAIDPRS--LYAKLGL----AQlalaenRFDEARAL 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 249 FERALSLaenEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 328
Cdd:TIGR02917 182 IDEVLTA---DPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAP 258

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1402371420 329 HMYEPHFNFATVSDKIGDLQRSYVAAQKSEVAFPEH 364
Cdd:TIGR02917 259 NSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEY 294
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 41-328 2.69e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.86  E-value: 2.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  41 INLSRLNLTKysQKPKLAKALFEYIL-HHENDVKMALDLASLSTEYSQYKD--WWWKVQIGK------CYYRLGMYREAE 111
Cdd:TIGR02917 503 ANLARIDIQE--GNPDDAIQRFEKVLtIDPKNLRAILALAGLYLRTGNEEEavAWLEKAAELnpqeiePALALAQYYLGK 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 112 KQFKSALK-QQEMVDT-------FLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKE 183
Cdd:TIGR02917 581 GQLKKALAiLNEAADAapdspeaWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKR 660

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 184 VLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAA 263
Cdd:TIGR02917 661 ALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAI 740

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1402371420 264 dvwyNLGHIAVGIGDTNLAHQcfRLALVHNNH--HAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 328
Cdd:TIGR02917 741 ----KLHRALLASGNTAEAVK--TLEAWLKTHpnDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 238-362 5.13e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 51.88  E-value: 5.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 238 YAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQAR 317
Cdd:COG5010    29 AALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAK 108

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1402371420 318 ALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEVAFP 362
Cdd:COG5010   109 EYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
100-188 5.20e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.17  E-value: 5.20e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 100 CYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVTALNlFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAA 178
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDpDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|
gi 1402371420 179 EYYKEVLKQD 188
Cdd:COG3063    80 AYLERALELD 89
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 89-196 7.02e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.77  E-value: 7.02e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  89 KDWWWKVQIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARI 167
Cdd:COG4235    15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRlDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLA 94

                          90       100
                  ....*....|....*....|....*....
gi 1402371420 168 YEEMNNSSSAAEYYKEVLKQDNTHVEAIA 196
Cdd:COG4235    95 AFQQGDYAEAIAAWQKLLALLPADAPARL 123
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
227-328 1.53e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.84  E-value: 1.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 227 QLFNNLGLCCFYAQQYDMTLTSFERALSLaenEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVL 306
Cdd:COG4785    74 QLYYERGVAYDSLGDYDLAIADFDQALEL---DPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIA 150

                          90       100
                  ....*....|....*....|..
gi 1402371420 307 EMRKGHVEQARALLQTASSLAP 328
Cdd:COG4785   151 LYYLGRYELAIADLEKALELDP 172
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 89-188 1.72e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 1.72e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  89 KDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEM-VDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARI 167
Cdd:COG4783    36 DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDePEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARA 115

                          90       100
                  ....*....|....*....|.
gi 1402371420 168 YEEMNNSSSAAEYYKEVLKQD 188
Cdd:COG4783   116 YRALGRPDEAIAALEKALELD 136
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 98-365 2.70e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.78  E-value: 2.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  98 GKCYYRLGMYREAEKQFKSALKQQEMVDTFL-YLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSS 176
Cdd:TIGR02917 302 GASEYQLGNLEQAYQYLNQILKYAPNSHQARrLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEK 381

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 177 AAEYYKEVLKQD-----------------NTHVEAIA-----------------CIGSNHFYSDQPEVALRFYRRLLQMG 222
Cdd:TIGR02917 382 AAEYLAKATELDpenaaartqlgisklsqGDPSEAIAdletaaqldpelgradlLLILSYLRSGQFDKALAAAKKLEKKQ 461

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 223 VYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAAdvwYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNN 302
Cdd:TIGR02917 462 PDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAA---ANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILA 538

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1402371420 303 LAVLEMRKGHVEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEVAFPEHV 365
Cdd:TIGR02917 539 LAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSP 601
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 99-290 5.71e-07

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 50.68  E-value: 5.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  99 KCYYRLGMYREAEKQFKSALKQQEMVDTFL--YLAKVYI-ILDQPVTALNLFKQGLDKFPGE----VTLLCGIARIYEEM 171
Cdd:COG3071   127 QAYRQLGDWEELLELLPALRKHKALSAEEAqaLERRAYLgLLRQAARDAEALKALWKALPRAerrdPELAAAYARALIAL 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 172 NNSSSAAEYYKEVLKQdNTHVEAIACIGSNHfySDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFER 251
Cdd:COG3071   207 GDHDEAERLLREALKR-QWDPRLVRLYGRLQ--GGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEA 283

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1402371420 252 ALSLAENeeeaADVWYNLGHIAVGIGDTNLAHQCFRLAL 290
Cdd:COG3071   284 ALALRPS----AEAYAELARLLEQLGDPEEAAEHYRKAL 318
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
277-363 8.23e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 46.70  E-value: 8.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 277 GDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARAlLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQK 356
Cdd:COG3063     6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLER 84


                  ....*..
gi 1402371420 357 SEVAFPE 363
Cdd:COG3063    85 ALELDPS 91
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 110-321 2.01e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 2.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 110 AEKQFKSALK--------QQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLcGIARIYEEMNNSSSAAEYY 181
Cdd:TIGR02917 681 AAKRTESAKKiakslqkqHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKTL 759

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 182 KEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLccFYAQQYD-MTLTSFERALSLAENEE 260
Cdd:TIGR02917 760 EAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAW--LYLELKDpRALEYAERALKLAPNIP 837

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1402371420 261 EAADVwynLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQ 321
Cdd:TIGR02917 838 AILDT---LGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEARKELD 895
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 99-187 3.01e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 45.75  E-value: 3.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  99 KCYYRLGMYREAEKQFKSALKQ----QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTL---LCGIARIYEEM 171
Cdd:COG1729     1 KALLKAGDYDEAIAAFKAFLKRypnsPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLEL 80

                          90
                  ....*....|....*.
gi 1402371420 172 NNSSSAAEYYKEVLKQ 187
Cdd:COG1729    81 GDYDKARATLEELIKK 96
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 55-217 5.30e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.45  E-value: 5.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  55 PKLAKALFEY--ILHHENDVKMALDLASLSTEYsQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLA 131
Cdd:COG3914   109 PDNAEALFNLgnLLLALGRLEEALAALRRALAL-NPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDpDNAEALNNLG 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 132 KVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNsSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVA 211
Cdd:COG3914   188 NALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACD-WEVYDRFEELLAALARGPSELSPFALLYLPDDDPAEL 266


                  ....*.
gi 1402371420 212 LRFYRR 217
Cdd:COG3914   267 LALARA 272
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 237-328 4.02e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 42.29  E-value: 4.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 237 FYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHH---AEAYNNLAVLEMRKGHV 313
Cdd:COG1729     4 LKAGDYDEAIAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSpkaPDALLKLGLSYLELGDY 83

                          90
                  ....*....|....*
gi 1402371420 314 EQARALLQTASSLAP 328
Cdd:COG1729    84 DKARATLEELIKKYP 98
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 96-156 4.18e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 42.29  E-value: 4.18e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1402371420  96 QIGKCYYRLGMYREAEKQFKSALKQ----QEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPG 156
Cdd:COG1729    35 WLGEAYYALGDYDEAAEAFEKLLKRypdsPKAPDALLKLGLSYLELGDYDKARATLEELIKKYPD 99
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 96-374 5.87e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.07  E-value: 5.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  96 QIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNS 174
Cdd:TIGR02917 402 QLGISKLSQGDPSEAIADLETAAQlDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDL 481

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 175 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFnnLGLCCFYAQQYD--MTLTSFERA 252
Cdd:TIGR02917 482 AKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAI--LALAGLYLRTGNeeEAVAWLEKA 559

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 253 LSLAENEEEAAdvwYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPHMYE 332
Cdd:TIGR02917 560 AELNPQEIEPA---LALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSAL 636

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1402371420 333 PHFNFATVSDKIGDLQRSYVAAQKSEVAFPEHVDTQHLIKQL 374
Cdd:TIGR02917 637 ALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQL 678
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 51-188 9.48e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.25  E-value: 9.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  51 YSQKPKLAKALFEYILHHENDVKMALDLASLSTEYSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLY 129
Cdd:COG5010    14 LLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDpNNPELYYN 93

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1402371420 130 LAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQD 188
Cdd:COG5010    94 LALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 166-256 1.44e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.87  E-value: 1.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 166 RIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMT 245
Cdd:COG5010    62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141

                          90
                  ....*....|.
gi 1402371420 246 LTSFERALSLA 256
Cdd:COG5010   142 KAALQRALGTS 152
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 202-290 1.77e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 1.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 202 HFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHIAVGIGDTNL 281
Cdd:COG5010    64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDN---PNAYSNLAALLLSLGQDDE 140


                  ....*....
gi 1402371420 282 AHQCFRLAL 290
Cdd:COG5010   141 AKAALQRAL 149
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 262-349 1.80e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.79  E-value: 1.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 262 AADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPHMYEPHFNFATVS 341
Cdd:COG2956     7 AALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDY 86


                  ....*...
gi 1402371420 342 DKIGDLQR 349
Cdd:COG2956    87 LKAGLLDR 94
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
167-256 4.05e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 4.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 167 IYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFyRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTL 246
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|
gi 1402371420 247 TSFERALSLA 256
Cdd:COG3063    80 AYLERALELD 89
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 64-157 4.23e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 4.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  64 YILHHENDVKMALDLASLSTEYSQyKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYIILDQPVT 142
Cdd:COG4783    46 EILLQLGDLDEAIVLLHEALELDP-DEPEARLNLGLALLKAGDYDEALALLEKALKLDpEHPEAYLRLARAYRALGRPDE 124

                          90
                  ....*....|....*
gi 1402371420 143 ALNLFKQGLDKFPGE 157
Cdd:COG4783   125 AIAALEKALELDPDD 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 107-220 6.50e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 6.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 107 YREAEKQFKSALKQQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLK 186
Cdd:COG5010    37 TKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALA 116

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1402371420 187 QDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQ 220
Cdd:COG5010   117 LSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
TPR_12 pfam13424
Tetratricopeptide repeat;
226-290 6.69e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.14  E-value: 6.69e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 226 CQLFNNLGLCCFYAQQYDMTLTSFERALSLAENE-----EEAADVWYNLGHIAVGIGDTNLAHQCFRLAL 290
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhPLTATTLLNLGRLYLELGRYEEALELLERAL 72
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
250-336 1.05e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.28  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 250 ERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPH 329
Cdd:COG4785    60 AERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD 139


                  ....*..
gi 1402371420 330 MYEPHFN 336
Cdd:COG4785   140 YAYAYLN 146
LPA1 PLN03098
LOW PSII ACCUMULATION1; Provisional
 231-290 2.92e-03

LOW PSII ACCUMULATION1; Provisional


Pssm-ID: 215573 [Multi-domain]  Cd Length: 453  Bit Score: 39.49  E-value: 2.92e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 231 NLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLAL 290
Cdd:PLN03098   80 NLGLSLFSKGRVKDALAQFETALELNPNPDEAQAAYYNKACCHAYREEGKKAADCLRTAL 139
TPR_12 pfam13424
Tetratricopeptide repeat;
261-327 7.79e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 35.06  E-value: 7.79e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1402371420 261 EAADVWYNLGHIAVGIGDTNLAHQCFRLAL-----VHNNHH---AEAYNNLAVLEMRKGHVEQARALLQTASSLA 327
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALeiarrLLGPDHpltATTLLNLGRLYLELGRYEEALELLERALALA 75
TPR_12 pfam13424
Tetratricopeptide repeat;
95-186 8.85e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 35.06  E-value: 8.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420  95 VQIGKCYYRLGMYREAEKQFKSALKQQEmvdtflylakvyiildqpvtalnlfKQGLDKFPGEVTLLCGIARIYEEMNNS 174
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIAR-------------------------RLLGPDHPLTATTLLNLGRLYLELGRY 61

                          90
                  ....*....|..
gi 1402371420 175 SSAAEYYKEVLK 186
Cdd:pfam13424  62 EEALELLERALA 73
TPR_hemY_coli TIGR00540
heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized ...
 225-289 9.50e-03

heme biosynthesis-associated TPR protein; Members of this protein family are uncharacterized tetratricopeptide repeat (TPR) proteins invariably found in heme biosynthesis gene clusters. The absence of any invariant residues other than Ala argues against this protein serving as an enzyme per se. The gene symbol hemY assigned in E. coli is unfortunate in that an unrelated protein, protoporphyrinogen oxidase (HemG in E. coli) is designated HemY in Bacillus subtilis. [Unknown function, General]


Pssm-ID: 273126 [Multi-domain]  Cd Length: 367  Bit Score: 37.65  E-value: 9.50e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1402371420 225 NCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEeaadVWYNLGHIAVGIGDTNLAHQCFRLA 289
Cdd:TIGR00540 307 DALLLLALGRLCLRQQLWGKAQSYLEASLSLAPTEE----AHLELAQLFEQLGDTEAAAQHYRKS 367
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 250-369 9.81e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 38.05  E-value: 9.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1402371420 250 ERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPH 329
Cdd:COG3914    31 ELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPD 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1402371420 330 MYEPHFNFATVSDKIGDLQRSYVAAQKSEVAFPEHVDTQH 369
Cdd:COG3914   111 NAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYL 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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