|
Name |
Accession |
Description |
Interval |
E-value |
| HkD_Girdin |
cd22229 |
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation ... |
10-165 |
1.02e-89 |
|
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration.
Pssm-ID: 411800 Cd Length: 156 Bit Score: 288.23 E-value: 1.02e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 10 LEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVKQIKFY 89
Cdd:cd22229 1 LEQFMSSPLVTWVKTFGPLATGNGTPLDEYVALVDGVFLNEVMLQINPKSSNQRVNKKVNNDASLRIQNLSILVKQIKLY 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1390011543 90 YQETLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22229 81 YQETLQQLIMMSLPNVLVLGRNPLSEQGTEEMKKLLLLLLGCAVQCERKEEFIERIQTLDFDTKAAVAAHIQEVTH 156
|
|
| HkD_Daple |
cd22228 |
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) ... |
13-165 |
1.05e-61 |
|
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) and similar proteins; Protein Daple, also called coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling.
Pssm-ID: 411799 Cd Length: 153 Bit Score: 207.85 E-value: 1.05e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 13 FMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQE 92
Cdd:cd22228 1 FLQSPLVTWVKTFGPLGFGSEDKLSMYMDLVDGVFLNKIMLQIDPRPTNQRVNKHVNNDVNLRIQNLTILVRHIKTYYQE 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 93 TLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22228 81 VLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKMLLLVLGCAVQCERKEEFIERIKQLDIETQAAIVSHIQEVTH 153
|
|
| HkD_HkRP |
cd22223 |
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, ... |
13-165 |
7.06e-61 |
|
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration. Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing. All family members contain a conserved globular Hook domain which folds as a variant of the helical calponin homology (CH) domain.
Pssm-ID: 411794 Cd Length: 149 Bit Score: 205.52 E-value: 7.06e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 13 FMTSPLVTWVKTFgplaAGNGTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQE 92
Cdd:cd22223 1 FLSSPLVTWAKTF----ADDGSAELSYTDLVDGVFLNNVMLQIDPRPFSEVSNRNVDDDVNARIQNLDLLLRNIKSFYQE 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 93 TLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22223 77 VLQQLIVMKLPDILTIGREPESEQSLEELEKLLLLLLGCAVQCERKEEFIERIKNLDLEVQHALVACIQEVTD 149
|
|
| HkD_Gipie |
cd22230 |
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar ... |
11-164 |
1.43e-37 |
|
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar proteins; Gipie, also called coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing.
Pssm-ID: 411801 Cd Length: 170 Bit Score: 139.58 E-value: 1.43e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 11 EQFMTSPLVTWVKTF------------GPLAAGNGTNLD---EYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDASLR 75
Cdd:cd22230 1 EEFMSGALVTWALGFeglvgeeedslgFPEEEEEEGTLDaekRFLRLSNGDLLNRVMGIIDPSPRGGPRMRGDDGPAAHR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 76 IHNLSILVKQIKFYYQETLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAA 155
Cdd:cd22230 81 VQNLHILWGRLRDFYQEELQQLILSPPPDLQVMGRDPFTEEAVQELEKLLRLLLGAAVQCERRELFIRHIQGLDLDVQAE 160
|
....*....
gi 1390011543 156 VAAHIQEVT 164
Cdd:cd22230 161 LAEAIQEVT 169
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
258-1079 |
1.79e-23 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 108.99 E-value: 1.79e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 258 AKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLEseLSRYKERLH 337
Cdd:TIGR02168 165 AGISKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLR--LEELREELE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 338 DIEFYKARVEELKEDNQVLLETktmLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Cdd:TIGR02168 243 ELQEELKEAEEELEELTAELQE---LEEKLEELRLEvselEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLE 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 414 TLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELtSSKLLKLEMENQSLTKTVEELRSTADSAAGS---- 489
Cdd:TIGR02168 320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL-EAELEELESRLEELEEQLETLRSKVAQLELQiasl 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 490 TSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQ--NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTV 567
Cdd:TIGR02168 399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkELQAELEELEEELEELQEELERLEEALEELREELEEAEQALD 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 568 SSLRQRSQISAEARV-KDIEKENKILHESIKEtcgklskIEFEKRQMKKELELYKEKGERAEELENELNHLGKENeLLQK 646
Cdd:TIGR02168 479 AAERELAQLQARLDSlERLQENLEGFSEGVKA-------LLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGR-LQAV 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 647 KITNLKITCEKLETLEQENS--------------ELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVES 712
Cdd:TIGR02168 551 VVENLNAAKKAIAFLKQNELgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 713 LKCASMRMAQLQLENKELESEKEQLRKGlelmRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEME 792
Cdd:TIGR02168 631 LDNALELAKKLRPGYRIVTLDGDLVRPG----GVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 793 NQTLQKSLEELKI----SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKT 868
Cdd:TIGR02168 707 LEELEEELEQLRKeleeLSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 869 LFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQs 948
Cdd:TIGR02168 787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE- 865
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 949 tddsrykLLESKLESTLKKSLEIK---EEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSG 1025
Cdd:TIGR02168 866 -------ELIEELESELEALLNERaslEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRI 938
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 1390011543 1026 EddkwgrESQEATREllKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL 1079
Cdd:TIGR02168 939 D------NLQERLSE--EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
581-1373 |
7.89e-23 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 107.06 E-value: 7.89e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 581 RVKDIEKENKIlhESIKETCGKLSKIEFE-KRQMKKeLELYKEKGERAEELENELNHLgkENELLQKKITNLKitcEKLE 659
Cdd:TIGR02168 171 KERRKETERKL--ERTRENLDRLEDILNElERQLKS-LERQAEKAERYKELKAELREL--ELALLVLRLEELR---EELE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 660 TLEQENSELERENRKFKKTLdsfKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRM-AQLQLENKELESEKEQLR 738
Cdd:TIGR02168 243 ELQEELKEAEEELEELTAEL---QELEEKLEELRLEVSELEEEIEELQKELYALANEISRLeQQKQILRERLANLERQLE 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 739 KGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENK 818
Cdd:TIGR02168 320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR---SKVAQLELQIA 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKigNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRAT 898
Cdd:TIGR02168 397 SLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEELQEELERLEEALEELREELEEAE 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 899 IDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD-----EQSTDDSRYKL-----LESKLESTLKKS 968
Cdd:TIGR02168 475 QALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIlgvlsELISVDEGYEAaieaaLGGRLQAVVVEN 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 969 LEIKEEKIAALE-------ARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIP------------------- 1022
Cdd:TIGR02168 555 LNAAKKAIAFLKqnelgrvTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvddldna 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1023 -------------VSGEDDKWGRES-------------QEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN 1076
Cdd:TIGR02168 635 lelakklrpgyriVTLDGDLVRPGGvitggsaktnssiLERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL 714
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1077 NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQvenstlnsqstslmNQNAQLLIQQSSLENENESIMKEREDLKSLYDAL 1156
Cdd:TIGR02168 715 EQLRKELEELSRQISALRKDLARLEAEVEQLE--------------ERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1157 IKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKG----QLEDLEKMIKTEQEKMllESKN 1232
Cdd:TIGR02168 781 EAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAaterRLEDLEEQIEELSEDI--ESLA 858
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1233 HEVVASEYKKlcgenDRLNYTYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDitstklnnqcEL 1312
Cdd:TIGR02168 859 AEIEELEELI-----EELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELR----------EK 923
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1390011543 1313 LSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKL 1373
Cdd:TIGR02168 924 LAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
610-1224 |
4.77e-22 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 103.99 E-value: 4.77e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 610 KRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQL 689
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEIS---SELPELREELEKLEKEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 690 ESLEKENSQLDEENLELRRSVESLKcasmrmaqlqLENKELEsekeqlrkglelmrasfKKTERLEvSYQGLDTENQRLQ 769
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELK----------KEIEELE-----------------EKVKELK-ELKEKAEEYIKLS 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 770 KALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE----KENKRLRQQA 845
Cdd:PRK03918 300 EFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEeakaKKEELERLKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 846 EIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKELvKRATIDIKTlVTLREDLVSEKLKTQQMNNDL 925
Cdd:PRK03918 380 RLTGLTPEKLEKELEELEKAKEEIEEEISKITA---RIGELKKEIKEL-KKAIEELKK-AKGKCPVCGRELTEEHRKELL 454
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 926 EKLTHELEKIGLNKERLLHDEqstddSRYKLLESKLESTLKKSLE-IKEEKIAALEARLEESTN-YNQQlrhELKTVKKN 1003
Cdd:PRK03918 455 EEYTAELKRIEKELKEIEEKE-----RKLRKELRELEKVLKKESElIKLKELAEQLKELEEKLKkYNLE---ELEKKAEE 526
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1004 YEALKQRQDEERMVQSSIpvsgeddkwgresQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN-NNLQAQ 1082
Cdd:PRK03918 527 YEKLKEKLIKLKGEIKSL-------------KKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEER 593
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1083 ILALQ---RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaqlliqqSSLENENESIMKEREDLKSLYDAliKD 1159
Cdd:PRK03918 594 LKELEpfyNEYLELKDAEKELEREEKELKKLEEELDKAFEEL-----------AETEKRLEELRKELEELEKKYSE--EE 660
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 1160 HEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQE 1224
Cdd:PRK03918 661 YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
|
|
| HkD_SF |
cd22211 |
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ... |
16-165 |
1.67e-21 |
|
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.
Pssm-ID: 411792 Cd Length: 145 Bit Score: 92.72 E-value: 1.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 16 SPLVTWVKTFGPLaagngTNLDEYVALVDGVFLNQVMLQINPKSESQRVNKKVNNDAS--LRIHNLSILVKQIKFYYQET 93
Cdd:cd22211 2 AALLAWINTFPLS-----SPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSSDNwvLKLNNLKKLYRSLSKYYREV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 94 LQQLIM-MPLPDILIIGKNPfseqGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22211 77 LGQQLSdLPLPDLSAIARDG----DEEEIVKLLELVLGAAVQCENKEEYIARIQQLDESTQAELMLIIQEVLE 145
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
250-875 |
4.26e-21 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 101.29 E-value: 4.26e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 250 SVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDARSARMYRDEL-----DALREKAVRVDK 324
Cdd:TIGR02168 224 ELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK----LEELRLEVSELEEEieelqKELYALANEISR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 325 LESELSRYKERLH----DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEM 396
Cdd:TIGR02168 300 LEQQKQILRERLAnlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEEleslEAELEELEAELEELESRLEELEE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 397 ERDMDRKKIEELmEENMTLEMAQKQSMDESLH-LGWELEQ-ISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTK 474
Cdd:TIGR02168 380 QLETLRSKVAQL-ELQIASLNNEIERLEARLErLEDRRERlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELER 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 475 TVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILEN-------------EIIQEKQSLQNCQNLSKDLMKEKAQLEKT 541
Cdd:TIGR02168 459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAA 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 542 IET-LRENSErqiKILEQENEHLNQTVSSLRQ----RSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKE 616
Cdd:TIGR02168 539 IEAaLGGRLQ---AVVVENLNAAKKAIAFLKQnelgRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 617 -------------------LELYKEKGERAE---------------------------ELENELNHLGKENELLQKKITN 650
Cdd:TIGR02168 616 kalsyllggvlvvddldnaLELAKKLRPGYRivtldgdlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAE 695
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 651 LKITCEKLET--------LEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVES---------- 712
Cdd:TIGR02168 696 LEKALAELRKeleeleeeLEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEleerleeaee 775
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 713 -LKCASMRMAQLQLENKELESEKEQLRKGL--------ELMRASFKKTERLEVSYQGLD---TENQRLQKALENSNKKIQ 780
Cdd:TIGR02168 776 eLAEAEAEIEELEAQIEQLKEELKALREALdelraeltLLNEEAANLRERLESLERRIAateRRLEDLEEQIEELSEDIE 855
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 781 QLESELQDLEMENQTLQKSLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Cdd:TIGR02168 856 SLAAEIEELEELIEELESELEAL---LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932
|
730
....*....|....*
gi 1390011543 861 NLEKENKTLFKEINV 875
Cdd:TIGR02168 933 GLEVRIDNLQERLSE 947
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
705-1378 |
1.20e-20 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 99.75 E-value: 1.20e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 705 ELRRSVESLKcasmRMAQLQLENKELESEKEQLRKGLELMRASFKKTE--RLEVSYQGLDTENQRLQKALENSNKKIQQL 782
Cdd:TIGR02168 197 ELERQLKSLE----RQAEKAERYKELKAELRELELALLVLRLEELREEleELQEELKEAEEELEELTAELQELEEKLEEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 783 ESELQDLEMENQTLQKSLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Cdd:TIGR02168 273 RLEVSELEEEIEELQKELYALAN---EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 863 eKENKTLFKEinvykescvRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERL 942
Cdd:TIGR02168 350 -KEELESLEA---------ELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 943 LHD----EQSTDDSRYKLLESKLEST------LKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQD 1012
Cdd:TIGR02168 420 QQEieelLKKLEEAELKELQAELEELeeeleeLQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1013 EERMVQSSI--------------PVSGE----DDKWGRESQEATRELLKvkdrLIEVERNNATLQA-------------- 1060
Cdd:TIGR02168 500 NLEGFSEGVkallknqsglsgilGVLSElisvDEGYEAAIEAALGGRLQ----AVVVENLNAAKKAiaflkqnelgrvtf 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1061 --------------EKQALKTQ------LKQLETQNNNLQ----------------AQILALQRQT------VSLQ---- 1094
Cdd:TIGR02168 576 lpldsikgteiqgnDREILKNIegflgvAKDLVKFDPKLRkalsyllggvlvvddlDNALELAKKLrpgyriVTLDgdlv 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1095 ------------EQNTTLQTQN--AKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDH 1160
Cdd:TIGR02168 656 rpggvitggsakTNSSILERRReiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDL 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1161 EKLELLHERQASEYESLiskHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEY 1240
Cdd:TIGR02168 736 ARLEAEVEQLEERIAQL---SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL 812
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1241 KklcgendRLNYTYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL 1320
Cdd:TIGR02168 813 T-------LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL 885
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*...
gi 1390011543 1321 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHvEQRqyiDKLNELRRQKEKLEEKIM 1378
Cdd:TIGR02168 886 EEALALLRSELEELSEELRELESKRSELRRELE-ELR---EKLAQLELRLEGLEVRID 939
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
181-814 |
2.02e-20 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 98.60 E-value: 2.02e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 181 MSQEDIEPLLKNMVSHLRRLIDERDEHSETIVELSEERDGVHflphasssaqspcgspgmKRTESRQHLSVELADAKAKI 260
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE------------------KEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 261 RRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnllsdarsarmyRDELDALREKAVRVDKLESELSRYKERLHDIE 340
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEK--------------VKELKELKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 341 fykarveelkednqvllETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEmerdmdrKKIEELMEENMTLEMAqK 420
Cdd:PRK03918 314 -----------------KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELE-------KRLEELEERHELYEEA-K 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 421 QSMDESLHL-----GWELEQISRTSELAEAPQKSLGHEVNELTsSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILK 495
Cdd:PRK03918 369 AKKEELERLkkrltGLTPEKLEKELEELEKAKEEIEEEISKIT-ARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 496 VEKENQRLNKKVEIleneiiqekqslqncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENE--HLNQTVSSLRQR 573
Cdd:PRK03918 448 EHRKELLEEYTAEL-------------------KRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKEL 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 574 SQISAEARVKDIEKENKiLHESIKEtcgKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKI 653
Cdd:PRK03918 509 EEKLKKYNLEELEKKAE-EYEKLKE---KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGF 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 654 TCekLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELrrsveslkcasmrmaqlqlenKELESE 733
Cdd:PRK03918 585 ES--VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEEL---------------------AETEKR 641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 734 KEQLRKGLELMRASF--KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLE 811
Cdd:PRK03918 642 LEELRKELEELEKKYseEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALE 721
|
...
gi 1390011543 812 QLE 814
Cdd:PRK03918 722 RVE 724
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
309-1209 |
2.79e-20 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 98.60 E-value: 2.79e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 309 RDELDALREKAVRVDKLESELSRYKERLH----DIEFYKARVEELKEDNQ-VLLETKTMLEDQLEGTRARsdkLHELEKE 383
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDEKRQQLERLRrereKAERYQALLKEKREYEGyELLKEKEALERQKEAIERQ---LASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTL---EMAQKQSMDESLHLgwELEQISRTSELAEAPQKslghevneltss 460
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeEQLRVKEKIGELEA--EIASLERSIAEKERELE------------ 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 461 kllklEMENQsLTKTVEELRSTAdsaagstSKILKVEKENQRLNKKVEILENEIIQEKQSLQncqnlskDLMKEKAQLEK 540
Cdd:TIGR02169 319 -----DAEER-LAKLEAEIDKLL-------AEIEELEREIEEERKRRDKLTEEYAELKEELE-------DLRAELEEVDK 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 541 TIETLRENSERQIKILEQENEHLNqtvSSLRQRSQISAEARVKDIEKENkiLHESIKETCGKLSKIEFEKrqmkkelely 620
Cdd:TIGR02169 379 EFAETRDELKDYREKLEKLKREIN---ELKRELDRLQEELQRLSEELAD--LNAAIAGIEAKINELEEEK---------- 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 621 KEKGERAEELENELNHLGKENELLQKKITNLKitcEKLETLEQENSELEREnrkfkktldsfknltfqLESLEKENSQLD 700
Cdd:TIGR02169 444 EDKALEIKKQEWKLEQLAADLSKYEQELYDLK---EEYDRVEKELSKLQRE-----------------LAEAEAQARASE 503
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 701 EENLELRRSVESLK--------------------------CASMRMAQLQLENKELESEKEQLRKGLELMRASF-----K 749
Cdd:TIGR02169 504 ERVRGGRAVEEVLKasiqgvhgtvaqlgsvgeryataievAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFlplnkM 583
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 750 KTERLEVSYQGLD----------TENQRLQKA---------LENSNKKIQQLESELQDLEMENQTLQKS------LEELK 804
Cdd:TIGR02169 584 RDERRDLSILSEDgvigfavdlvEFDPKYEPAfkyvfgdtlVVEDIEAARRLMGKYRMVTLEGELFEKSgamtggSRAPR 663
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLK 884
Cdd:TIGR02169 664 GGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE---RLE 740
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 885 ELEKENKELVKRATIDIKTLVTLREDLvseklktQQMNNDLEKLTHELEKIglnkerllhdEQSTDDSRYKLLESKLESt 964
Cdd:TIGR02169 741 ELEEDLSSLEQEIENVKSELKELEARI-------EELEEDLHKLEEALNDL----------EARLSHSRIPEIQAELSK- 802
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 965 LKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRqdeermvqssipvsgeddkwgRESQEATRELLKV 1044
Cdd:TIGR02169 803 LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQ---------------------IKSIEKEIENLNG 861
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1045 KDRliEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQtvsLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQ 1124
Cdd:TIGR02169 862 KKE--ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERK---IEELEAQIEKKRKRL----SELKAKLEALEEE 932
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1125 NAQLLIQQSSLENENESIMKErEDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQ 1204
Cdd:TIGR02169 933 LSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEE 1011
|
....*
gi 1390011543 1205 LLKQK 1209
Cdd:TIGR02169 1012 YEKKK 1016
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
529-1229 |
3.56e-20 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 98.21 E-value: 3.56e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 529 KDLMKEKAQLEKTI---ETLRENSERQIKILEQENEHLNQTVSSLRQRSQI------SAEARVKDIEKENKILHESIKET 599
Cdd:TIGR02168 235 EELREELEELQEELkeaEEELEELTAELQELEEKLEELRLEVSELEEEIEElqkelyALANEISRLEQQKQILRERLANL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 600 CGKLSKIEFEKRQMKKELELYKEkgeRAEELENELNHLGKENELLQKKITNLKITCEKLETLEQE-NSELERENRKFKKT 678
Cdd:TIGR02168 315 ERQLEELEAQLEELESKLDELAE---ELAELEEKLEELKEELESLEAELEELEAELEELESRLEElEEQLETLRSKVAQL 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 679 LDSFKNLTFQLESLEKENSQLDEENLELRRSVESLkcasmRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSY 758
Cdd:TIGR02168 392 ELQIASLNNEIERLEARLERLEDRRERLQQEIEEL-----LKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 759 QGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRL--------EQLEKENK---SLE---QET 824
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvlsELISVDEGyeaAIEaalGGR 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 825 SQ--LEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKEnkelVKRATIDIK 902
Cdd:TIGR02168 547 LQavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK----LRKALSYLL 622
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 903 TLVTLREDLvseklktQQMNNDLEKLTHELEKIGLNKERLlhdeqSTDDSRYKLLESKLESTLKKSLEIKE--EKIAALE 980
Cdd:TIGR02168 623 GGVLVVDDL-------DNALELAKKLRPGYRIVTLDGDLV-----RPGGVITGGSAKTNSSILERRREIEEleEKIEELE 690
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 981 ARLEESTNYNQQLRHELKTVKKNYEALKQRQDE-------------------ERMVQSSIPVSGEDDKWGRESQEATREL 1041
Cdd:TIGR02168 691 EKIAELEKALAELRKELEELEEELEQLRKELEElsrqisalrkdlarleaevEQLEERIAQLSKELTELEAEIEELEERL 770
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1042 LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL 1121
Cdd:TIGR02168 771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1122 mnqNAQLLIQQSSLENENESIMKEREDLKSLYDALikdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDR 1201
Cdd:TIGR02168 851 ---SEDIESLAAEIEELEELIEELESELEALLNER----ASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923
|
730 740 750
....*....|....*....|....*....|.
gi 1390011543 1202 YNQLLKQKGQLEDLEKMIK---TEQEKMLLE 1229
Cdd:TIGR02168 924 LAQLELRLEGLEVRIDNLQerlSEEYSLTLE 954
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
250-1075 |
5.58e-20 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 97.45 E-value: 5.58e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 250 SVELADAKAKIRRLRQELE------EKTEQLLDCKQELEQIEVELKRLQQENMNllsdaRSARMYRDELDALREKAVRVD 323
Cdd:TIGR02169 183 EENIERLDLIIDEKRQQLErlrrerEKAERYQALLKEKREYEGYELLKEKEALE-----RQKEAIERQLASLEEELEKLT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 324 KLESELS-RYKERLHDIEFYKARVEELKEDNQVLLETKtMLEDQLEGTRARS------DKLHELEKENLQLKAKLHDMEM 396
Cdd:TIGR02169 258 EEISELEkRLEEIEQLLEELNKKIKDLGEEEQLRVKEK-IGELEAEIASLERsiaekeRELEDAEERLAKLEAEIDKLLA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 397 ERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKS-------LGHEVNELtSSKLLKLEMEN 469
Cdd:TIGR02169 337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDyreklekLKREINEL-KRELDRLQEEL 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 470 QSLTKTVEELRStadSAAGSTSKILKVEKENQRLNKKVEILEneiiqekqslQNCQNLSKDLMKEKAQLEKTIETLREnS 549
Cdd:TIGR02169 416 QRLSEELADLNA---AIAGIEAKINELEEEKEDKALEIKKQE----------WKLEQLAADLSKYEQELYDLKEEYDR-V 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 550 ERQIKILEQENEHLNQTVSSLRQRsQISAEARVKDIEKENKILHESIKE---------------TCGKLSKIEFEKRQMK 614
Cdd:TIGR02169 482 EKELSKLQRELAEAEAQARASEER-VRGGRAVEEVLKASIQGVHGTVAQlgsvgeryataievaAGNRLNNVVVEDDAVA 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 615 KE-LELYKE-KGERAEELE-NELNHLGKENELLQKK-----ITNLkITCEKL----------ETLEQENSELEREnrkfk 676
Cdd:TIGR02169 561 KEaIELLKRrKAGRATFLPlNKMRDERRDLSILSEDgvigfAVDL-VEFDPKyepafkyvfgDTLVVEDIEAARR----- 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 677 kTLDSFKNLTFQLESLEKENS----------------QLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRkg 740
Cdd:TIGR02169 635 -LMGKYRMVTLEGELFEKSGAmtggsraprggilfsrSEPAELQRLRERLEGLK---RELSSLQSELRRIENRLDELS-- 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 741 lELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLE--ELKISSKRLEQLEKENK 818
Cdd:TIGR02169 709 -QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEelEEDLHKLEEALNDLEAR 787
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKELVKRat 898
Cdd:TIGR02169 788 LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE---QIKSIEKEIENLNGK-- 862
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 899 idiktlvtlREDLVSEKLKTQQMNNDLEKlthelEKIGLNKERLLHDEQstddsrYKLLESKLEsTLKKSLEIKEEKIAA 978
Cdd:TIGR02169 863 ---------KEELEEELEELEAALRDLES-----RLGDLKKERDELEAQ------LRELERKIE-ELEAQIEKKRKRLSE 921
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 979 LEARLEestNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATL 1058
Cdd:TIGR02169 922 LKAKLE---ALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKL 998
|
890
....*....|....*..
gi 1390011543 1059 QAEKQALKTQLKQLETQ 1075
Cdd:TIGR02169 999 EEERKAILERIEEYEKK 1015
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
497-1282 |
6.62e-20 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 97.35 E-value: 6.62e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQI 576
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 577 SAEARVKDIEKENKILHESIKEtcgkLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCE 656
Cdd:pfam02463 249 EQEEIESSKQEIEKEEEKLAQV----LKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 657 KLETLEQENSELERENRKFKKTLD----SFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELE- 731
Cdd:pfam02463 325 KAEKELKKEKEEIEELEKELKELEikreAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEe 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 732 ---SEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQksLEELKISSK 808
Cdd:pfam02463 405 keaQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL--LKETQLVKL 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKES--CVRLKEL 886
Cdd:pfam02463 483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVsaTADEVEE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 887 EKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLK 966
Cdd:pfam02463 563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 967 KSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGE--DDKWGRESQEATRELLKV 1044
Cdd:pfam02463 643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKkkEQREKEELKKLKLEAEEL 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1045 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ 1124
Cdd:pfam02463 723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1125 NAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELlhERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQ 1204
Cdd:pfam02463 803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELK--EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1390011543 1205 LLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLNYTYSQLLKETEILQMDHKNLKSVLNNSKLEQ 1282
Cdd:pfam02463 881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
505-1262 |
8.31e-20 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 97.06 E-value: 8.31e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 505 KKVEILENEIIQEKQSLQNCQNLS---KDLMKEKAQLE--------KTIETLRENSERQIKILEQENEHLNQTVSSLRQR 573
Cdd:TIGR02169 187 ERLDLIIDEKRQQLERLRREREKAeryQALLKEKREYEgyellkekEALERQKEAIERQLASLEEELEKLTEEISELEKR 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 574 SQiSAEARVKDIEKENKILHE----SIKETCGKLS--------KIEFEKRQMK-------KELELYKEKGERAEELENEL 634
Cdd:TIGR02169 267 LE-EIEQLLEELNKKIKDLGEeeqlRVKEKIGELEaeiaslerSIAEKERELEdaeerlaKLEAEIDKLLAEIEELEREI 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 635 NHLGKENELLQKKITNLKitcEKLETLEQENSELERENRKFKKTLDSFKnltfqlESLEKENSQLDEENLELRRSVESLK 714
Cdd:TIGR02169 346 EEERKRRDKLTEEYAELK---EELEDLRAELEEVDKEFAETRDELKDYR------EKLEKLKREINELKRELDRLQEELQ 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 715 CASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERlevsyqgldtENQRLQKALENSNKKIQQLESELQDLEMENQ 794
Cdd:TIGR02169 417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----------KLEQLAADLSKYEQELYDLKEEYDRVEKELS 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 795 TLQKSLEELKISSKRLEQLEKENKSLEQE-----------TSQLEKDKKQ----LEKENKRLRQQAEIKDTTLEENNVKI 859
Cdd:TIGR02169 487 KLQRELAEAEAQARASEERVRGGRAVEEVlkasiqgvhgtVAQLGSVGERyataIEVAAGNRLNNVVVEDDAVAKEAIEL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 860 GNLEKENKTLFKEINVYKES---------------CVRLKELEKENKELVK---------------RATIDIKTLVTLRE 909
Cdd:TIGR02169 567 LKRRKAGRATFLPLNKMRDErrdlsilsedgvigfAVDLVEFDPKYEPAFKyvfgdtlvvedieaaRRLMGKYRMVTLEG 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 910 DLV---------------------SEKLKTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDSRYKLLESKLE-STLKK 967
Cdd:TIGR02169 647 ELFeksgamtggsraprggilfsrSEPAELQRLRERLEGLKRELSSL---QSELRRIENRLDELSQELSDASRKiGEIEK 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 968 SLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGED----------DKWGRESQEA 1037
Cdd:TIGR02169 724 EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlearlshsriPEIQAELSKL 803
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1038 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNsq 1117
Cdd:TIGR02169 804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLE-- 881
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1118 stslmnqnaqlliqqsslenenesimKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKD 1197
Cdd:TIGR02169 882 --------------------------SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 1198 LEDRYNQLLKQKGQLEDLEKMIKT----EQEKMLLESKN------HEVVASEYKKLCGENDRLNYTYSQLLKETE 1262
Cdd:TIGR02169 936 IEDPKGEDEEIPEEELSLEDVQAElqrvEEEIRALEPVNmlaiqeYEEVLKRLDELKEKRAKLEEERKAILERIE 1010
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
543-1073 |
2.58e-19 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 95.13 E-value: 2.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 543 ETLRENSERQIKILEQENEHLnqtvsslrqRSQISAEARVKDIEKENKilhESIKETCGKLSKIEFEKRQMKKELELYKE 622
Cdd:PRK03918 161 ENAYKNLGEVIKEIKRRIERL---------EKFIKRTENIEELIKEKE---KELEEVLREINEISSELPELREELEKLEK 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 623 KGERAEELENELNHLGKENELLQKKITNLKI----TCEKLETLEQENSELERENRKFKK---------TLDSFKNLTFQ- 688
Cdd:PRK03918 229 EVKELEELKEEIEELEKELESLEGSKRKLEEkireLEERIEELKKEIEELEEKVKELKElkekaeeyiKLSEFYEEYLDe 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 689 LESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLEL---MRASFKKTERLEVSYQGLDTEN 765
Cdd:PRK03918 309 LREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeeAKAKKEELERLKKRLTGLTPEK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 766 -----QRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELK-------ISSKRLEQLEKEN--KSLEQETSQLEKDK 831
Cdd:PRK03918 389 lekelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpVCGRELTEEHRKEllEEYTAELKRIEKEL 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 832 KQLEKENKRLRQQAEIKDTTLEENNVKIGNLE--KENKTLFKEINVYKescvrLKELEKENKEL--VKRATIDIKTLVtl 907
Cdd:PRK03918 469 KEIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYN-----LEELEKKAEEYekLKEKLIKLKGEI-- 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 908 rEDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLES---------TLKKS---LEIKEEK 975
Cdd:PRK03918 542 -KSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKElepfyneylELKDAekeLEREEKE 620
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 976 IAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQssipVSGEDDKWGRESQEATRELLKVKDRLIEVERNN 1055
Cdd:PRK03918 621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEE----LREEYLELSRELAGLRAELEELEKRREEIKKTL 696
|
570
....*....|....*...
gi 1390011543 1056 ATLQAEKQALKTQLKQLE 1073
Cdd:PRK03918 697 EKLKEELEEREKAKKELE 714
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
605-1220 |
5.98e-19 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 94.23 E-value: 5.98e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 605 KIEFEKRQMKKELEL--YKEKGERAEELENELNHLGKENELLQKKITNLKitceklETLEQENSELERENRKFKKTLDSF 682
Cdd:COG1196 217 ELKEELKELEAELLLlkLRELEAELEELEAELEELEAELEELEAELAELE------AELEELRLELEELELELEEAQAEE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 683 KNLTFQLESLEKENSQLDEENLELRRsveslkcasmRMAQLQLENKELESEKEQLRKGLELMRASFKK-TERLEVSYQGL 761
Cdd:COG1196 291 YELLAELARLEQDIARLEERRRELEE----------RLEELEEELAELEEELEELEEELEELEEELEEaEEELEEAEAEL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 762 DTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Cdd:COG1196 361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 842 RQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEScVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQm 921
Cdd:COG1196 441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAA-LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG- 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 922 NNDLEKLTHELEKIGLNKE---------RLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQ 992
Cdd:COG1196 519 LRGLAGAVAVLIGVEAAYEaaleaalaaALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIG 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 993 LRHELKTVKKNYEALKQRQDEERMVQSSIpvsgEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQL 1072
Cdd:COG1196 599 AAVDLVASDLREADARYYVLGDTLLGRTL----VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAAL 674
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1073 ETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSL 1152
Cdd:COG1196 675 LEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1390011543 1153 YDALIKDHEKLellhERQASEYESLISKHGTLksahkNL--EVEHKDLEDRYNQLLKQKGQLE----DLEKMIK 1220
Cdd:COG1196 755 ELPEPPDLEEL----ERELERLEREIEALGPV-----NLlaIEEYEELEERYDFLSEQREDLEeareTLEEAIE 819
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
257-891 |
1.44e-18 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 92.82 E-value: 1.44e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 257 KAKIRRLRQEL---EEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREK----AVRVDKLESEL 329
Cdd:PRK03918 175 KRRIERLEKFIkrtENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEieelEKELESLEGSK 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 330 SRYKERLHDIEfykARVEELKEDNQVLLETKTMLEdQLEGTRARSDKLHELEKENLQLKAK----LHDMEMERDMDRKKI 405
Cdd:PRK03918 255 RKLEEKIRELE---ERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREiekrLSRLEEEINGIEERI 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 406 EELMEENMTLEMAQKQsMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELrstads 485
Cdd:PRK03918 331 KELEEKEERLEELKKK-LKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEI------ 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 486 aagsTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKE--KAQLEKTIETLRENSERQIKILEQENEHL 563
Cdd:PRK03918 404 ----EEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEhrKELLEEYTAELKRIEKELKEIEEKERKLR 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 564 NQTVsslRQRSQISAEARVKDIEKenkiLHESIKETCGKLSKIEFEKrqMKKELELYKEKGERAEELENELNHLGKENEL 643
Cdd:PRK03918 480 KELR---ELEKVLKKESELIKLKE----LAEQLKELEEKLKKYNLEE--LEKKAEEYEKLKEKLIKLKGEIKSLKKELEK 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 644 LQKKITNLKITCEKLETLEQENSELERENRKFKktLDSFKNLTFQLESLEKensqLDEENLELRRSVESLKCASMRMAQL 723
Cdd:PRK03918 551 LEELKKKLAELEKKLDELEEELAELLKELEELG--FESVEELEERLKELEP----FYNEYLELKDAEKELEREEKELKKL 624
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 724 QLENKELESEKEQLRKGLELMRasfKKTERLEVSYQgldtenqrlQKALENSNKKIQQLESELQDLEMENQTLQKSLEEL 803
Cdd:PRK03918 625 EEELDKAFEELAETEKRLEELR---KELEELEKKYS---------EEEYEELREEYLELSRELAGLRAELEELEKRREEI 692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ-QAEIKDTTLEennvKIGNLEKEnktLFKEINVYKESCVR 882
Cdd:PRK03918 693 KKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKyKALLKERALS----KVGEIASE---IFEELTEGKYSGVR 765
|
....*....
gi 1390011543 883 LKelEKENK 891
Cdd:PRK03918 766 VK--AEENK 772
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
594-1375 |
2.58e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 92.05 E-value: 2.58e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 594 ESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLgKENELLQKKITNLKitceKLETLEQENSELERENR 673
Cdd:TIGR02169 180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREY-EGYELLKEKEALER----QKEAIERQLASLEEELE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 674 KFKKTLDSF-KNLTFQLESLEKENSQL----DEENLELRRSVESLKcASMRMAQLQLENKELESEK--EQLRKGLELMRA 746
Cdd:TIGR02169 255 KLTEEISELeKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELE-AEIASLERSIAEKERELEDaeERLAKLEAEIDK 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 747 SFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQkslEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR02169 334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR---DELKDYREKLEKLKREINELKRELDR 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 827 LEKDKKQLEKENKRLRQQAEIK-------DTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKE----LEKENKELVK 895
Cdd:TIGR02169 411 LQEELQRLSEELADLNAAIAGIeakinelEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydrVEKELSKLQR 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 896 RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEI-KEE 974
Cdd:TIGR02169 491 ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELlKRR 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 975 KIAAL------EARLEES-----------------TNYNQQLRHELK------TVKKNYEALKQRQDEERMV-------- 1017
Cdd:TIGR02169 571 KAGRAtflplnKMRDERRdlsilsedgvigfavdlVEFDPKYEPAFKyvfgdtLVVEDIEAARRLMGKYRMVtlegelfe 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1018 QSSIPVSGEDDKWGRESQEATR--ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQE 1095
Cdd:TIGR02169 651 KSGAMTGGSRAPRGGILFSRSEpaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1096 QNTTLQTQNAKLQVEnstLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDAL-------IKDH-EKLELLH 1167
Cdd:TIGR02169 731 EEEKLKERLEELEED---LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshsripeIQAElSKLEEEV 807
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1168 ERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEvvaseykklcgen 1247
Cdd:TIGR02169 808 SRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE------------- 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1248 drlnYTYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHL 1327
Cdd:TIGR02169 875 ----AALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE 950
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 1390011543 1328 LD------QIQTLMLQNRTLLEQNMESKDLFHVEQRQYidklNELRRQKEKLEE 1375
Cdd:TIGR02169 951 LSledvqaELQRVEEEIRALEPVNMLAIQEYEEVLKRL----DELKEKRAKLEE 1000
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
350-1108 |
3.17e-18 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 91.72 E-value: 3.17e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 350 KEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQ-----LKAKLHDMEMERDmdrkkieelmeenmtlEMAQKQSmd 424
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRqsvidLQTKLQEMQMERD----------------AMADIRR-- 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 425 eslhlgweleqisRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKtVEELRSTADSAAGSTSKILKVEKENQRLN 504
Cdd:pfam15921 135 -------------RESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ-IEQLRKMMLSHEGVLQEIRSILVDFEEAS 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 505 KKvEILENEIIQEKQSLQNCQNLSKDLMKEKAQL----------EKTIETLRENSERQIKIL-EQENEHLNQTVSS---- 569
Cdd:pfam15921 201 GK-KIYEHDSMSTMHFRSLGSAISKILRELDTEIsylkgrifpvEDQLEALKSESQNKIELLlQQHQDRIEQLISEheve 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 570 ---LRQRSQiSAEARVKDIEKENKILHESIKETCG----KLSKIEFEKRQMKKELELYKEKGE-RAEELE-------NEL 634
Cdd:pfam15921 280 itgLTEKAS-SARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEdKIEELEkqlvlanSEL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 635 NHLGKENELLQKKITNLKITCEKL-ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKEnsqLDEENLELRRSVESL 713
Cdd:pfam15921 359 TEARTERDQFSQESGNLDDQLQKLlADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE---LDDRNMEVQRLEALL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 714 KC--------ASMRMAQLQLENK----------ELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENS 775
Cdd:pfam15921 436 KAmksecqgqMERQMAAIQGKNEslekvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAT 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 776 NKKIQQLES-------ELQDLEMEN---QTLQKSLEELKIS----SKRLEQLEKENKSLEQETSQ-------LEKDKKQL 834
Cdd:pfam15921 516 NAEITKLRSrvdlklqELQHLKNEGdhlRNVQTECEALKLQmaekDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQL 595
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 835 EKE--NKRLRQQ-----AEIKDTTLEENNVKIGNLEKENKTLfkeINVYKESCVRLKELEKENKELVKRATIDIKTLVTL 907
Cdd:pfam15921 596 EKEinDRRLELQefkilKDKKDAKIRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSL 672
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 908 REDLVSEKL----KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLesKLESTLKKSLEIKEEKIAALEAR- 982
Cdd:pfam15921 673 SEDYEVLKRnfrnKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM--KVAMGMQKQITAKRGQIDALQSKi 750
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 983 --LEESTNYNQQLRHELKtvkknyealkqrQDEERMVQSSIPVSGEDDKWGREsqeatRELLKVKDRLIEVERNNATLQA 1060
Cdd:pfam15921 751 qfLEEAMTNANKEKHFLK------------EEKNKLSQELSTVATEKNKMAGE-----LEVLRSQERRLKEKVANMEVAL 813
|
810 820 830 840
....*....|....*....|....*....|....*....|....*...
gi 1390011543 1061 EKQALKTQLKQLETQNNNLQAQILALQrQTVSLQEQNTTLQTQNAKLQ 1108
Cdd:pfam15921 814 DKASLQFAECQDIIQRQEQESVRLKLQ-HTLDVKELQGPGYTSNSSMK 860
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
464-1205 |
2.74e-17 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 88.15 E-value: 2.74e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 464 KLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Cdd:TIGR04523 97 KINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELN 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 544 TLRenserqikileqenehlnqtvsslrqrsqisaearvKDIEKENKilhesiketcgKLSKIEFEKRQMKKELELYKEK 623
Cdd:TIGR04523 177 LLE------------------------------------KEKLNIQK-----------NIDKIKNKLLKLELLLSNLKKK 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 624 GERAEELENELNHLGKENELLQKkitnlkitcekleTLEQENSELERENRKFKKTLDSFKNLTfqlESLEKENSQLDEEN 703
Cdd:TIGR04523 210 IQKNKSLESQISELKKQNNQLKD-------------NIEKKQQEINEKTTEISNTQTQLNQLK---DEQNKIKKQLSEKQ 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 704 LELRRSVESLKCASMRMAQLQLENKELESEKEQlrkglELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLE 783
Cdd:TIGR04523 274 KELEQNNKKIKELEKQLNQLKSEISDLNNQKEQ-----DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLK 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 784 SELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTtleennvKIGNLE 863
Cdd:TIGR04523 349 KELTNSESENSEKQRELEEKQ---NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDE-------QIKKLQ 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 864 KENKTLFKEINvykescvRLKELEKENKELVKRATIDIKTLVTLREDLvseKLKTQQMNNDLEKLTHELEKIGLNKERll 943
Cdd:TIGR04523 419 QEKELLEKEIE-------RLKETIIKNNSEIKDLTNQDSVKELIIKNL---DNTRESLETQLKVLSRSINKIKQNLEQ-- 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 944 hdeqstddsrykllesklestLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPV 1023
Cdd:TIGR04523 487 ---------------------KQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1024 SGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQ 1103
Cdd:TIGR04523 546 ELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKE 625
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1104 NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALI---KDHEKLELLHERQASEYESLISK 1180
Cdd:TIGR04523 626 NEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIelmKDWLKELSLHYKKYITRMIRIKD 705
|
730 740
....*....|....*....|....*
gi 1390011543 1181 HGTLKSAHKNLEVEHKDLEDRYNQL 1205
Cdd:TIGR04523 706 LPKLEEKYKEIEKELKKLDEFSKEL 730
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
266-895 |
3.43e-17 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 88.15 E-value: 3.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 266 ELEEKTEQLLDCKQELEQIEVELKRLQQenmNLLSDARSARMYRDELDALREKAV-----------RVDKLESELSRYKE 334
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNLDK---NLNKDEEKINNSNNKIKILEQQIKdlndklkknkdKINKLNSDLSKINS 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 335 RLH-DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELmeenm 413
Cdd:TIGR04523 111 EIKnDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNI----- 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 414 tlemaqKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNEL--TSSKLLK-LEMENQSLTKTVEELRSTADSAAGST 490
Cdd:TIGR04523 186 ------QKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELkkQNNQLKDnIEKKQQEINEKTTEISNTQTQLNQLK 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 491 SKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQ-LEKTIETLRENSERQIKILEQENEHLNQTVSS 569
Cdd:TIGR04523 260 DEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdWNKELKSELKNQEKKLEEIQNQISQNNKIISQ 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 570 LRQRSQiSAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKgerAEELENELNHLGKENELLQKKIt 649
Cdd:TIGR04523 340 LNEQIS-QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQ---INDLESKIQNQEKLNQQKDEQI- 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 650 nlkitceklETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEENLELRRSVESLKcasMRMAQLQLENKE 729
Cdd:TIGR04523 415 ---------KKLQQEKELLEKEIERLKETIIKNNS---EIKDLTNQDSVKELIIKNLDNTRESLE---TQLKVLSRSINK 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 730 LESEKEQLRKGLELMRASFKKterLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKI---- 805
Cdd:TIGR04523 480 IKQNLEQKQKELKSKEKELKK---LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFelkk 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 806 ---------SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVY 876
Cdd:TIGR04523 557 enlekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNI 636
|
650
....*....|....*....
gi 1390011543 877 KESCVRLKELEKENKELVK 895
Cdd:TIGR04523 637 KSKKNKLKQEVKQIKETIK 655
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
701-1015 |
8.25e-17 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 86.91 E-value: 8.25e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 701 EENL--------ELRRSVESLKcasmRMAQLQLENKELESEKEQLRKGLEL--MRASFKKTERLEVSYQGLDTENQRLQK 770
Cdd:COG1196 185 EENLerledilgELERQLEPLE----RQAEKAERYRELKEELKELEAELLLlkLRELEAELEELEAELEELEAELEELEA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 771 ALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Cdd:COG1196 261 ELAELEAELEELRLELEELELELEEAQAEEYELL---AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 851 TLEENNVKIGNLEKEnktlfkeinvYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Cdd:COG1196 338 ELEELEEELEEAEEE----------LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 931 ELEKIGLNKERLLHDEQSTDDSRYKLLESKLEstLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQR 1010
Cdd:COG1196 408 AEEALLERLERLEEELEELEEALAELEEEEEE--EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485
|
....*
gi 1390011543 1011 QDEER 1015
Cdd:COG1196 486 LAEAA 490
|
|
| HkD_Hook |
cd22222 |
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes ... |
15-163 |
1.08e-16 |
|
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes Hook1-3. Hook1 is a microtubule-binding protein required for spermatid differentiation. Hook2, also a microtubule-binding protein, contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. Hook adaptor proteins share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain, and contacts the helix alpha1 of dynein light intermediate chain 1 (LIC1) in a hydrophobic groove.
Pssm-ID: 411793 Cd Length: 147 Bit Score: 78.83 E-value: 1.08e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 15 TSPLVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPKSESQ----RVNKKVNNDASLRIHNLSILVKQIKFYY 90
Cdd:cd22222 1 CDSLLQWLQTFN-LIAPHATAED----LSDGVAIAQVLNQIDPEYFSDswlsKIKPDVGDNWRLKVSNLKKILKGIVDYY 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1390011543 91 QETL-QQLIMMPLPDILIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22222 76 SEVLgQQISGFTMPDVNAIAEK----EDPKELGRLLQLVLGCAVNCERKEEYIQAIMGLEESVQHVVMEAIQEL 145
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
325-888 |
1.72e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 85.89 E-value: 1.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 325 LESELSRYK--ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR 402
Cdd:PRK03918 141 LESDESREKvvRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELR 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 403 KKIEELMEENMTLEmaqkqsmdeslHLGWELEQISRTSELAEAPQKSLGHEVNELTSS--KLLKLEMENQSLTKTVEELR 480
Cdd:PRK03918 221 EELEKLEKEVKELE-----------ELKEEIEELEKELESLEGSKRKLEEKIRELEERieELKKEIEELEEKVKELKELK 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 481 STADSAAGSTSKILKVEKENQRLNKKVEILENEI--IQEK-QSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE 557
Cdd:PRK03918 290 EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEIngIEERiKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKA 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 558 QENEhLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYK---------------- 621
Cdd:PRK03918 370 KKEE-LERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgreltee 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 622 EKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELerenRKFKKTLDSFKNL-----TFQLESLEKEN 696
Cdd:PRK03918 449 HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEL----IKLKELAEQLKELeeklkKYNLEELEKKA 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 697 SQ---LDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGL-----ELMRASFKKTERLEVSYQGLDTENQRL 768
Cdd:PRK03918 525 EEyekLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELaellkELEELGFESVEELEERLKELEPFYNEY 604
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 769 QKaLENSNKKIQQLESELQDLEMEnqtLQKSLEELKISSKRLEQLEKENKSLEQETSqlEKDKKQLEKENKRLRQQAEIK 848
Cdd:PRK03918 605 LE-LKDAEKELEREEKELKKLEEE---LDKAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGL 678
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 1390011543 849 DTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEK 888
Cdd:PRK03918 679 RAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEK 718
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
197-833 |
2.36e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 85.89 E-value: 2.36e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 197 LRRLIDERDEHSETIVELSEERDGVHFLPHASSSAQSPCGspgmKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLD 276
Cdd:TIGR02169 370 RAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELD----RLQEELQRLSEELADLNAAIAGIEAKINELEEEKED 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 277 CKQELEQIEVELKRLQQEnmnlLSDarsarmYRDELDALREKavrVDKLESELSRYKERLHDIEfykARVEELKEDNQVL 356
Cdd:TIGR02169 446 KALEIKKQEWKLEQLAAD----LSK------YEQELYDLKEE---YDRVEKELSKLQRELAEAE---AQARASEERVRGG 509
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 357 LETKTMLEDQLEGTRARSDKLHELEKE-----NLQLKAKLHDMEMERDMDRKK-IEELMEEN---MTL----EMAQKQSM 423
Cdd:TIGR02169 510 RAVEEVLKASIQGVHGTVAQLGSVGERyataiEVAAGNRLNNVVVEDDAVAKEaIELLKRRKagrATFlplnKMRDERRD 589
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 424 DESLH----LGWELEQISRTSELAEAPQKSLGHE--VNELTSSK-------LLKLE---------MENQSLTKTVEELRS 481
Cdd:TIGR02169 590 LSILSedgvIGFAVDLVEFDPKYEPAFKYVFGDTlvVEDIEAARrlmgkyrMVTLEgelfeksgaMTGGSRAPRGGILFS 669
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 482 TADSA--AGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE---NSERQIKIL 556
Cdd:TIGR02169 670 RSEPAelQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKErleELEEDLSSL 749
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI----LHESIKETCGKLSKIEFEKRQMKKelelykekgeRAEELEN 632
Cdd:TIGR02169 750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlSHSRIPEIQAELSKLEEEVSRIEA----------RLREIEQ 819
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 633 ELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSfknltfQLESLEKENSQLDEENLELRRSVES 712
Cdd:TIGR02169 820 KLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEE------ELEELEAALRDLESRLGDLKKERDE 893
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 713 LKcasMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKA---LENSNKKIQQLESELQDL 789
Cdd:TIGR02169 894 LE---AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEelsLEDVQAELQRVEEEIRAL 970
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 1390011543 790 EMEN----QTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:TIGR02169 971 EPVNmlaiQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
769-1321 |
2.46e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 85.50 E-value: 2.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 769 QKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqAEIK 848
Cdd:PRK03918 199 EKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELK--KEIE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 849 DttLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREdlvseklktqqMNNDLEKL 928
Cdd:PRK03918 277 E--LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE-----------KEERLEEL 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 929 THELEKIGLNKERLLHDEQSTDDSRYKLLE-SKLESTLK-KSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEA 1006
Cdd:PRK03918 344 KKKLKELEKRLEELEERHELYEEAKAKKEElERLKKRLTgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1007 LKQRQDEERMVQSSIPVSG---EDDKWGRESQEATRELLKVKDRLIEVErnnatlqAEKQALKTQLKQLETqnnnlqaqI 1083
Cdd:PRK03918 424 LKKAIEELKKAKGKCPVCGrelTEEHRKELLEEYTAELKRIEKELKEIE-------EKERKLRKELRELEK--------V 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1084 LALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQqssLENENESIMKEREDLKSLYDALIKDHEKL 1163
Cdd:PRK03918 489 LKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIK---LKGEIKSLKKELEKLEELKKKLAELEKKL 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1164 ELLhERQASEYESLISKHGTlkSAHKNLEVEHKDLE---DRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEY 1240
Cdd:PRK03918 566 DEL-EEELAELLKELEELGF--ESVEELEERLKELEpfyNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRL 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1241 KKLCGENDRLNYTYSqllketeilQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL 1320
Cdd:PRK03918 643 EELRKELEELEKKYS---------EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL 713
|
.
gi 1390011543 1321 E 1321
Cdd:PRK03918 714 E 714
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
257-943 |
2.66e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 85.37 E-value: 2.66e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnllsdARSARMYRdeldALREKAVRVDkLESELSRYKERL 336
Cdd:COG1196 171 KERKEEAERKLEATEENLERLEDILGELERQLEPLERQ-------AEKAERYR----ELKEELKELE-AELLLLKLRELE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 337 HDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRArsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE 416
Cdd:COG1196 239 AELEELEAELEELEAELEELEAELAELEAELEELRL---ELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 417 MAQKQsmdeslhLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADSAAgstsKILKV 496
Cdd:COG1196 316 ERLEE-------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE----ELEEL 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQI 576
Cdd:COG1196 385 AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 577 SAEARVKDIEKENKILHESIKEtcGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQ-KKITNLKITC 655
Cdd:COG1196 465 LAELLEEAALLEAALAELLEEL--AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGvEAAYEAALEA 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 656 EKLETLEQENSELERENRKFKKTLDSFKN--LTFQLESLEKENSQLDEENLELRRS------VESLKCASMRMAQLQLEN 727
Cdd:COG1196 543 ALAAALQNIVVEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGaavdlvASDLREADARYYVLGDTL 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 728 KELESEKEQLRKGLELMRASfkkTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISS 807
Cdd:COG1196 623 LGRTLVAARLEAALRRAVTL---AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN----KTLFKEINVYKEscvRL 883
Cdd:COG1196 700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEppdlEELERELERLER---EI 776
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 884 KELEK-------ENKELVKRATidikTLVTLREDLVSEKlktqqmnNDLEKLTHELEKIGlnKERLL 943
Cdd:COG1196 777 EALGPvnllaieEYEELEERYD----FLSEQREDLEEAR-------ETLEEAIEEIDRET--RERFL 830
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
626-1323 |
6.92e-16 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 83.92 E-value: 6.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 626 RAEELENELNHLGKENELLQKKITNLkitcekletleqENSELERENRKfKKTLDSFKNLTFQLESLE----KENSQLDE 701
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNL------------DKNLNKDEEKI-NNSNNKIKILEQQIKDLNdklkKNKDKINK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 702 ENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSyqgLDTENQRLQKALENSNKKIQQ 781
Cdd:TIGR04523 101 LNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEK---LNNKYNDLKKQKEELENELNL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 782 LESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN 861
Cdd:TIGR04523 178 LEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQ 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 862 LEKENKTLfkeinvykescvrLKELEKENKELVKRATidiktlvtlredlvseklKTQQMNNDLEKLTHELEKigLNKER 941
Cdd:TIGR04523 258 LKDEQNKI-------------KKQLSEKQKELEQNNK------------------KIKELEKQLNQLKSEISD--LNNQK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 942 llhdeqstddsrykllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKnyealkQRQDEERmvqssi 1021
Cdd:TIGR04523 305 ----------------EQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK------ELTNSES------ 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1022 pvsgeddkwgrESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ 1101
Cdd:TIGR04523 357 -----------ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLE 425
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1102 TQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKH 1181
Cdd:TIGR04523 426 KEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEK 505
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1182 GTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVAS------EYKKLCGENDRLNYTYS 1255
Cdd:TIGR04523 506 KELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEideknkEIEELKQTQKSLKKKQE 585
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1390011543 1256 QLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEE 1323
Cdd:TIGR04523 586 EKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
136-839 |
8.11e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 83.96 E-value: 8.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 136 QKKEEFIEKIQGLDFDTKAAVAAHIQEVTHNQENVFDLQwmEVTDMSQEDIEPLLKNMVSHLRRLIDERDEHSETIVELS 215
Cdd:TIGR02169 272 QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSI--AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 216 EERDGVhflphasssaqspcGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEN 295
Cdd:TIGR02169 350 KRRDKL--------------TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 296 MNLLSDARSARM-------YRDELDA-LREKAVRVDKLESELSRYKErlhDIEFYKARVEELKEDNQVLLETKTMLEDQL 367
Cdd:TIGR02169 416 QRLSEELADLNAaiagieaKINELEEeKEDKALEIKKQEWKLEQLAA---DLSKYEQELYDLKEEYDRVEKELSKLQREL 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 368 EGTRARSDKLH----------ELEKENLQ-----------------------LKAKLHDMEMERDMDRKK-IEELMEEN- 412
Cdd:TIGR02169 493 AEAEAQARASEervrggraveEVLKASIQgvhgtvaqlgsvgeryataievaAGNRLNNVVVEDDAVAKEaIELLKRRKa 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 413 --MTL----EMAQKQSMDESLH----LGWELEQISRTSELAEAPQKSLGHE--VNELTSSK-------LLKLE------- 466
Cdd:TIGR02169 573 grATFlplnKMRDERRDLSILSedgvIGFAVDLVEFDPKYEPAFKYVFGDTlvVEDIEAARrlmgkyrMVTLEgelfeks 652
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 467 --MENQSLTKTVEELRSTADSA--AGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTI 542
Cdd:TIGR02169 653 gaMTGGSRAPRGGILFSRSEPAelQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE 732
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 543 ETLRE---NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI----LHESIKETCGKLSKIEFEKRQMKK 615
Cdd:TIGR02169 733 EKLKErleELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlSHSRIPEIQAELSKLEEEVSRIEA 812
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 616 elelykekgeRAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSfknltfQLESLEKE 695
Cdd:TIGR02169 813 ----------RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEE------ELEELEAA 876
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 696 NSQLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKA---L 772
Cdd:TIGR02169 877 LRDLESRLGDLKKERDELE---AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEelsL 953
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 773 ENSNKKIQQLESELQDLEMENqtlQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK 839
Cdd:TIGR02169 954 EDVQAELQRVEEEIRALEPVN---MLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKR 1017
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
606-1242 |
1.02e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.45 E-value: 1.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 606 IEFEKRQMKKELELYKEKGERAEELENELNHLgkENELLQKKITNLKitcEKLETLEQENSELERENRKFKKtldsfknl 685
Cdd:COG1196 194 ILGELERQLEPLERQAEKAERYRELKEELKEL--EAELLLLKLRELE---AELEELEAELEELEAELEELEA-------- 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 686 tfQLESLEKENSQLDEENLELRRSVEslkcasmrmaQLQLENKELESEKEQLRKGLELMRasfKKTERLEVSYQGLDTEN 765
Cdd:COG1196 261 --ELAELEAELEELRLELEELELELE----------EAQAEEYELLAELARLEQDIARLE---ERRRELEERLEELEEEL 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 766 QRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQA 845
Cdd:COG1196 326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE---EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 846 EIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQmnndl 925
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA----- 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 926 eklthelekiglnKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEestnynqQLRHELKTVKKNYE 1005
Cdd:COG1196 478 -------------ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLA-------GAVAVLIGVEAAYE 537
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1006 ALkqrqDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKD---RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQ 1082
Cdd:COG1196 538 AA----LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtflPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1083 ILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLydALIKDHEK 1162
Cdd:COG1196 614 RYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEE--LAERLAEE 691
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1163 LELLHERQASEYESLIskhgTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKK 1242
Cdd:COG1196 692 ELELEEALLAEEEEER----ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
278-1108 |
1.51e-15 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 83.10 E-value: 1.51e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 278 KQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKavrvdKLESELSRYKERLHDIEFYKARVEELKEDNQVLL 357
Cdd:pfam02463 173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYY-----QLKEKLELEEEYLLYLDYLKLNEERIDLLQELLR 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 358 ETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDmdrKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Cdd:pfam02463 248 DEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELK---LLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 438 RTSELAEAPQKSLGHEVNELTSSKLLKLEMEN------QSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILE 511
Cdd:pfam02463 325 KAEKELKKEKEEIEELEKELKELEIKREAEEEeeeeleKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 512 NEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQrsqisAEARVKDIEKENKI 591
Cdd:pfam02463 405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL-----ELKKSEDLLKETQL 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 592 LHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERE 671
Cdd:pfam02463 480 VKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADE 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 672 NRKFKKtldSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQL-ENKELESEKEQLRKGLELMRASFKK 750
Cdd:pfam02463 560 VEERQK---LVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKaTLEADEDDKRAKVVEGILKDTELTK 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 751 TERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Cdd:pfam02463 637 LKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLK 716
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 831 KKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE-----NKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLV 905
Cdd:pfam02463 717 LEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEeeksrLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKL 796
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 906 TLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSryKLLESKLESTLKKSLEIKEEKIAALEARLEE 985
Cdd:pfam02463 797 KAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELK--EEQKLEKLAEEELERLEEEITKEELLQELLL 874
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 986 STNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSI-PVSGEDDKWGRESQEA---------TRELLKVKDRLIEVERNN 1055
Cdd:pfam02463 875 KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNlLEEKENEIEERIKEEAeillkyeeePEELLLEEADEKEKEENN 954
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 1390011543 1056 A-TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQ 1108
Cdd:pfam02463 955 KeEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLI 1008
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
247-841 |
1.79e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 82.68 E-value: 1.79e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVEL--KRLQQENMNLLSDARSARmyrdeldaLREKAVRVDK 324
Cdd:COG1196 228 ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELeeLRLELEELELELEEAQAE--------EYELLAELAR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 325 LESELSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERDMDRKK 404
Cdd:COG1196 300 LEQDIARLEERRRELE---ERLEELEEELAELEEELEELEEELEELEEE---LEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 405 IEELMEENMTLEMAQKQSMDEslhlgwELEQISRTSELAEAPQKSLghevnELTSSKLLKLEMENQSLTKTVEELRSTAD 484
Cdd:COG1196 374 LAEAEEELEELAEELLEALRA------AAELAAQLEELEEAEEALL-----ERLERLEEELEELEEALAELEEEEEEEEE 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 485 SAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNcQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN 564
Cdd:COG1196 443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAE-LLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 565 QTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQmkkelelykeKGERAEELENELNHLGKENELL 644
Cdd:COG1196 522 LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA----------KAGRATFLPLDKIRARAALAAA 591
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 645 QKKITNLkitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQ 724
Cdd:COG1196 592 LARGAIG----AAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 725 LENKELESEKEQLRKGLELMRASFKKTERLEvsyqgLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELK 804
Cdd:COG1196 668 RELLAALLEAEAELEELAERLAEEELELEEA-----LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742
|
570 580 590
....*....|....*....|....*....|....*..
gi 1390011543 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Cdd:COG1196 743 EEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
262-1231 |
7.84e-15 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 80.60 E-value: 7.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 262 RLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSD-ARSARMYRDELDALREKAVRVDKLESELSRYKERLHDIE 340
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEkNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 341 fykARVEELKEDNQVLL-ETKTM------LEDQLEGTRARSDKLHeLEKENLQLKAK--------LHDMEMERDMDRKKI 405
Cdd:pfam01576 82 ---SRLEEEEERSQQLQnEKKKMqqhiqdLEEQLDEEEAARQKLQ-LEKVTTEAKIKkleedillLEDQNSKLSKERKLL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 406 EE--------LMEENMTLEMAQK-----QSMDESLHLGWELEQISRtSELAEAPQKSLGH--EVNELTSSKLLKLEMENQ 470
Cdd:pfam01576 158 EEriseftsnLAEEEEKAKSLSKlknkhEAMISDLEERLKKEEKGR-QELEKAKRKLEGEstDLQEQIAELQAQIAELRA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 471 SLTKTVEELRST---ADSAAGSTSKILKVEKENQRLNKKV-EILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIET-- 544
Cdd:pfam01576 237 QLAKKEEELQAAlarLEEETAQKNNALKKIRELEAQISELqEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTta 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 545 ----LRENSERQI----KILEQENEHLNQTVSSLRQ-----------------RSQISAEARVKDIEKENKILHESIKET 599
Cdd:pfam01576 317 aqqeLRSKREQEVtelkKALEEETRSHEAQLQEMRQkhtqaleelteqleqakRNKANLEKAKQALESENAELQAELRTL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 600 CGklSKIEFEKRQMKKELELYK-------------EKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENS 666
Cdd:pfam01576 397 QQ--AKQDSEHKRKKLEGQLQElqarlseserqraELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQ 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 667 ELERENRKFKktldsfKNLTFQLESLEKENSQLDE---ENLELRRSVESlkcasmrmaQLQLENKELESEKeqlrkglel 743
Cdd:pfam01576 475 ELLQEETRQK------LNLSTRLRQLEDERNSLQEqleEEEEAKRNVER---------QLSTLQAQLSDMK--------- 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 744 mrasfKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQE 823
Cdd:pfam01576 531 -----KKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKK 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 824 TSQLEKDKKQLEKENKRLRQQAEIKDTtleennvkignlEKENKTLfkeinvykeSCVRLKELEKENKELVKRATidiKT 903
Cdd:pfam01576 606 FDQMLAEEKAISARYAEERDRAEAEAR------------EKETRAL---------SLARALEEALEAKEELERTN---KQ 661
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 904 LVTLREDLVSEKLKTQQMNNDLEK----LTHELEKIGLNKERLLHDEQSTDDSRYKL------LESKLESTLKKSLEIKE 973
Cdd:pfam01576 662 LRAEMEDLVSSKDDVGKNVHELERskraLEQQVEEMKTQLEELEDELQATEDAKLRLevnmqaLKAQFERDLQARDEQGE 741
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 974 EKIAALEARLEEstnYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEddkwGREsqEATRELLKVKDRLIEVER 1053
Cdd:pfam01576 742 EKRRQLVKQVRE---LEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANK----GRE--EAVKQLKKLQAQMKDLQR 812
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1054 NNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQS 1133
Cdd:pfam01576 813 ELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIA 892
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1134 SLENENESIMKEREDLKSLYDALIKDHEKL--ELLHERQASEyesliskhgTLKSAHKNLEVEHKDLEDRYNQL-----L 1206
Cdd:pfam01576 893 QLEEELEEEQSNTELLNDRLRKSTLQVEQLttELAAERSTSQ---------KSESARQQLERQNKELKAKLQEMegtvkS 963
|
1050 1060
....*....|....*....|....*
gi 1390011543 1207 KQKGQLEDLEKMIKTEQEKMLLESK 1231
Cdd:pfam01576 964 KFKSSIAALEAKIAQLEEQLEQESR 988
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
556-1318 |
1.01e-14 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 80.16 E-value: 1.01e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 556 LEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHESIKETCGKLSKIEFEKRQMkkeLELYKEKGERAEELENELN 635
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELH----EKQKFYLRQSVIDLQTKLQEMQMERDAM---ADIRRRESQSQEDLRNQLQ 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 636 HLGKENELLQkkitnlkitCEKLETLEQENSELErenrKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKC 715
Cdd:pfam15921 149 NTVHELEAAK---------CLKEDMLEDSNTQIE----QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHF 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 716 ASMRMAQLQLEnKELESEKEQLR-------KGLELMRA-SFKKTERLevsyqgLDTENQRLQKALENSNKKIQQLESELQ 787
Cdd:pfam15921 216 RSLGSAISKIL-RELDTEISYLKgrifpveDQLEALKSeSQNKIELL------LQQHQDRIEQLISEHEVEITGLTEKAS 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 788 DLEMENQTLQKSLEELKISSKR-----LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Cdd:pfam15921 289 SARSQANSIQSQLEIIQEQARNqnsmyMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQF 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 863 EKENKTLFKEIN-VYKESCVRLKEL--EKE-NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKiglN 938
Cdd:pfam15921 369 SQESGNLDDQLQkLLADLHKREKELslEKEqNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQG---Q 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 939 KERLLHDEQSTDDSRYKL--LESKLESTlKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEA-------LKQ 1009
Cdd:pfam15921 446 MERQMAAIQGKNESLEKVssLTAQLEST-KEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAtnaeitkLRS 524
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1010 RQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAE--------KQALKTQLKQLETQNNNLQa 1081
Cdd:pfam15921 525 RVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgqhgrtAGAMQVEKAQLEKEINDRR- 603
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1082 qiLALQRQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHE 1161
Cdd:pfam15921 604 --LELQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE 677
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1162 KLELLHERQASEYESLISK-HGTLKSAHKNLEVEHKDLEDR--------------YNQLLKQKGQLEDLEKMIKTEQEKM 1226
Cdd:pfam15921 678 VLKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSMegsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEAM 757
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1227 LLESKNHEVVASEYKKLCGENDRLNYTYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKL 1306
Cdd:pfam15921 758 TNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRL 837
|
810
....*....|...
gi 1390011543 1307 NNQCEL-LSQLKG 1318
Cdd:pfam15921 838 KLQHTLdVKELQG 850
|
|
| HOOK_N |
pfam19047 |
HOOK domain; This domain is found at the N-terminus of HOOK proteins. |
18-163 |
1.12e-14 |
|
HOOK domain; This domain is found at the N-terminus of HOOK proteins.
Pssm-ID: 465958 Cd Length: 151 Bit Score: 73.21 E-value: 1.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 18 LVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPK--SES--QRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:pfam19047 6 LLTWLQTFN-VPAPCATVED----LTDGVAMAQVLHQIDPSwfTEAwlSRIKEDVGDNWRLKVSNLKKILQSVVDYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1390011543 94 L-QQLIMMPLPDILIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:pfam19047 81 LgQQISDFLLPDVNLIGEH----SDPAELGRLLQLILGCAVNCEKKQEYIQQIMTLEESVQHVVMTAIQEL 147
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
255-844 |
3.33e-14 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 78.54 E-value: 3.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 255 DAKAKIRRLrqeLEEKTEQLLDCKQELEQIEvelkrlQQENMNLLSDARSARMYRDE----LDALREKAV-RVDKLESEL 329
Cdd:PRK02224 173 DARLGVERV---LSDQRGSLDQLKAQIEEKE------EKDLHERLNGLESELAELDEeierYEEQREQAReTRDEADEVL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 330 SRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHElEKENLQLKAKLHDMEMERDMDRkkIEELM 409
Cdd:PRK02224 244 EEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEE-ERDDLLAEAGLDDADAEAVEAR--REELE 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 410 EEnmtLEMAQKQSMDESLHLGWELEQISRTSELAEapqkslghevneltsskllKLEMENQSLTKTVEELRSTADSAAgs 489
Cdd:PRK02224 321 DR---DEELRDRLEECRVAAQAHNEEAESLREDAD-------------------DLEERAEELREEAAELESELEEAR-- 376
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 490 tSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEK-------AQLEKTIETLRENSERQIKILE----- 557
Cdd:PRK02224 377 -EAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERdelrereAELEATLRTARERVEEAEALLEagkcp 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 558 ------QENEHLnQTVSSLRQRSQiSAEARVKDIEKENKILHESIkETCGKLSKIE--FEKRQMKKEL--ELYKEKGERA 627
Cdd:PRK02224 456 ecgqpvEGSPHV-ETIEEDRERVE-ELEAELEDLEEEVEEVEERL-ERAEDLVEAEdrIERLEERREDleELIAERRETI 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 628 EELENELNHLGKENELLQKKITnlkitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENlELR 707
Cdd:PRK02224 533 EEKRERAEELRERAAELEAEAE------EKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIA-DAE 605
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 708 RSVESLKCASMRMAQLQLENKELESEKEQLRKGLElmrASFKKtERLEvsyqGLDTENQRLQKALENSNKKIQQLESELQ 787
Cdd:PRK02224 606 DEIERLREKREALAELNDERRERLAEKRERKRELE---AEFDE-ARIE----EAREDKERAEEYLEQVEEKLDELREERD 677
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 788 DLEMENQTLQKSLEELKISSKRLEQLEKENKSLE---QETSQLEKDKKQLEKEnkrLRQQ 844
Cdd:PRK02224 678 DLQAEIGAVENELEELEELRERREALENRVEALEalyDEAEELESMYGDLRAE---LRQR 734
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
256-1097 |
3.53e-14 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 78.55 E-value: 3.53e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 256 AKAKIRRLRQELEEKTEQLLDCKQELEQIEVEL----KRLQQENMNLLSDARSARMYRDELDALREkavRVDKLESELSR 331
Cdd:TIGR00606 187 ALETLRQVRQTQGQKVQEHQMELKYLKQYKEKAceirDQITSKEAQLESSREIVKSYENELDPLKN---RLKEIEHNLSK 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 332 YKERLHDIEFYKARVEELKEDNQVLLETKTML----EDQL-EGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIE 406
Cdd:TIGR00606 264 IMKLDNEIKALKSRKKQMEKDNSELELKMEKVfqgtDEQLnDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKT 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 407 ELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGH-EVNELTSSKLLKLEMENQSLTKTVEELRSTADS 485
Cdd:TIGR00606 344 ELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErQIKNFHTLVIERQEDEAKTAAQLCADLQSKERL 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 486 AAGSTSKI--------LKVEKENQRLNKKVEILENEIIQekqsLQNCQNLSKDLMKEKAQLEKTIETL---RENS----- 549
Cdd:TIGR00606 424 KQEQADEIrdekkglgRTIELKKEILEKKQEELKFVIKE----LQQLEGSSDRILELDQELRKAERELskaEKNSltetl 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 550 --------------ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDiEKENKILHESIKETCGKLSKIEFEKRQMKK 615
Cdd:TIGR00606 500 kkevkslqnekadlDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKD-EQIRKIKSRHSDELTSLLGYFPNKKQLEDW 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 616 ELELYKEKGERAEEL----------ENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNL 685
Cdd:TIGR00606 579 LHSKSKEINQTRDRLaklnkelaslEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAML 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 686 TFQ-------LESLEKENS----------QLDEENLELRRSVES-LKCASMRMAQLQLENKELESEKEQLRkGLELMRAS 747
Cdd:TIGR00606 659 AGAtavysqfITQLTDENQsccpvcqrvfQTEAELQEFISDLQSkLRLAPDKLKSTESELKKKEKRRDEML-GLAPGRQS 737
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 748 F-----KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQ---DLEMENQTLQKSLEELKISSKRLEQLEKENKS 819
Cdd:TIGR00606 738 IidlkeKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEEsakVCLTDVTIMERFQMELKDVERKIAQQAAKLQG 817
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 820 --LEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRA 897
Cdd:TIGR00606 818 sdLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEV 897
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 898 TIDIKTLVTLRED---LVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEE 974
Cdd:TIGR00606 898 QSLIREIKDAKEQdspLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKET 977
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 975 KIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRqdeERMVQSSIPVSGEDDKWGRESQEATRELLKV-KDRLIEVER 1053
Cdd:TIGR00606 978 ELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQ---ERWLQDNLTLRKRENELKEVEEELKQHLKEMgQMQVLQMKQ 1054
|
890 900 910 920
....*....|....*....|....*....|....*....|....
gi 1390011543 1054 NNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1097
Cdd:TIGR00606 1055 EHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRD 1098
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
241-829 |
4.76e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 78.05 E-value: 4.76e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSD-ARSARMYRDELDALREKA 319
Cdd:COG1196 236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAElARLEQDIARLEERRRELE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 320 VRVDKLESELSRYKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERD 399
Cdd:COG1196 316 ERLEELEEELAELEEELEELE---EELEELEEELEEAEEELEEAEAELAEAEEA---LLEAEAELAEAEEELEELAEELL 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 400 MDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEEL 479
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 480 RSTADSAAGSTSKILKVEKENQRLNKKVEILEN-----EIIQEKQSLQNCQNLSK---DLMKEKAQLEKTIETLRENSER 551
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAARLLLLLEAEADyegflEGVKAALLLAGLRGLAGavaVLIGVEAAYEAALEAALAAALQ 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 552 QikILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETcGKLSKIEFEKRQMKKELELYKEKGERAEELE 631
Cdd:COG1196 550 N--IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARG-AIGAAVDLVASDLREADARYYVLGDTLLGRT 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 632 NELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSfknltfQLESLEKENSQLDEENLELRRSVE 711
Cdd:COG1196 627 LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE------AEAELEELAERLAEEELELEEALL 700
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 712 SLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKA-LENSNKKIQQLESELQDLE 790
Cdd:COG1196 701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPdLEELERELERLEREIEALG 780
|
570 580 590
....*....|....*....|....*....|....*....
gi 1390011543 791 MENQTlqkSLEELKISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:COG1196 781 PVNLL---AIEEYEELEERYDFLSEQREDLEEARETLEE 816
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
246-1089 |
1.84e-13 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 76.37 E-value: 1.84e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 246 RQHLSVELADAKAKIRRLRQELEEKTEQLldcKQELEQIEVELKRLQQEnmnllSDARSArmyrdELDALREkavrvdkL 325
Cdd:pfam01576 210 KRKLEGESTDLQEQIAELQAQIAELRAQL---AKKEEELQAALARLEEE-----TAQKNN-----ALKKIRE-------L 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 326 ESELSRYKERLHDIEFYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDmemerdmdrkk 404
Cdd:pfam01576 270 EAQISELQEDLESERAARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKKALEE----------- 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 405 iEELMEENMTLEMAQK--QSMDEslhLGWELEQISRTSELAEAPQKSLGHEVNEltssklLKLEMENQSLTKT-VEELRS 481
Cdd:pfam01576 339 -ETRSHEAQLQEMRQKhtQALEE---LTEQLEQAKRNKANLEKAKQALESENAE------LQAELRTLQQAKQdSEHKRK 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 482 TADSAAGS-TSKILKVEKENQRLNKKVEILENEIIQEKQSLQ----NCQNLSKDLMKEKAQLEKTIETLRENSeRQIKIL 556
Cdd:pfam01576 409 KLEGQLQElQARLSESERQRAELAEKLSKLQSELESVSSLLNeaegKNIKLSKDVSSLESQLQDTQELLQEET-RQKLNL 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 557 EQENEHLNQTVSSLRQRSQISAEARvKDIEKENKILHESIKETCGKLSK-------IEFEKRQMKKELELykeKGERAEE 629
Cdd:pfam01576 488 STRLRQLEDERNSLQEQLEEEEEAK-RNVERQLSTLQAQLSDMKKKLEEdagtleaLEEGKKRLQRELEA---LTQQLEE 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 630 LENELNHLGKENELLQKKITNLKItceKLETLEQENSELERENRKFKKTLDSFKNLTFQL---------ESLEKENSQLD 700
Cdd:pfam01576 564 KAAAYDKLEKTKNRLQQELDDLLV---DLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYaeerdraeaEAREKETRALS 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 701 -----EENLELRRSVESlkcaSMRMAQLQLEN------------KELESEKEQLRKGLELMRASFKKTE----------- 752
Cdd:pfam01576 641 laralEEALEAKEELER----TNKQLRAEMEDlvsskddvgknvHELERSKRALEQQVEEMKTQLEELEdelqatedakl 716
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 753 RLEVSYQGLDTENQR-LQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLE--------QLEKENKSLEQE 823
Cdd:pfam01576 717 RLEVNMQALKAQFERdLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEA 796
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 824 TSQLEKDK---KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVyKESCVRLKELEKE-------NKEL 893
Cdd:pfam01576 797 VKQLKKLQaqmKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGAS 875
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 894 VKRATIDIK-----TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG--LNKERLL---------HDEQSTDDSRYKL- 956
Cdd:pfam01576 876 GKSALQDEKrrleaRIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTteLAAERSTsqksesarqQLERQNKELKAKLq 955
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 957 -LESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHEL-KTVKKNYEALKQRQDEERMVqssipvsgedDKWGRES 1034
Cdd:pfam01576 956 eMEGTVKSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVrRTEKKLKEVLLQVEDERRHA----------DQYKDQA 1025
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 1035 QEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Cdd:pfam01576 1026 EKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSK 1080
|
|
| HkD_Hook3 |
cd22226 |
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein ... |
18-163 |
2.72e-13 |
|
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook3 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411797 Cd Length: 153 Bit Score: 69.23 E-value: 2.72e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 18 LVTWVKTFGPLAAGngTNLDEyvaLVDGVFLNQVMLQINP----KSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:cd22226 9 LLTWIQTFNVDAPC--QTVED---LTSGVVMAQVLQKIDPayfdENWLNRIKTEVGDNWRLKISNLKKILKGILDYNHEI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1390011543 94 L-QQLIMMPLPDILIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22226 84 LgQQINDFTLPDVNLIGEH----SDAAELGRMLQLILGCAVNCEQKQEYIQTIMMMEESVQHVVMTAIQEL 150
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
339-1148 |
5.89e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.79 E-value: 5.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 339 IEFYKA----RVEELKE--DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEN 412
Cdd:PTZ00121 1018 IDFNQNfnieKIEELTEygNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAF 1097
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 413 MTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKlEMENQSLTKTVEELRSTADSAAGSTSK 492
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE-DAKRVEIARKAEDARKAEEARKAEDAK 1176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 493 ILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ---ENEHLNQTVSS 569
Cdd:PTZ00121 1177 KAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaEEERNNEEIRK 1256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 570 LRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGE---RAEELENELNHLGKENELLQK 646
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEeakKADEAKKKAEEAKKKADAAKK 1336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 647 KITnlkitcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCAS--------- 717
Cdd:PTZ00121 1337 KAE------EAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEedkkkadel 1410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 718 MRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQtLQ 797
Cdd:PTZ00121 1411 KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE-AK 1489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 798 KSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKdttlEENNVKIGNLEKENKTLFKEINVYK 877
Cdd:PTZ00121 1490 KKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAK----KAEEKKKADELKKAEELKKAEEKKK 1565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 878 escVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLL 957
Cdd:PTZ00121 1566 ---AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE 1642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 958 --ESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQ 1035
Cdd:PTZ00121 1643 aeEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELK 1722
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1036 EATREllkvkdRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLN 1115
Cdd:PTZ00121 1723 KAEEE------NKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEV 1796
|
810 820 830
....*....|....*....|....*....|...
gi 1390011543 1116 SQSTSLMNQNAQLLIQQSSLENENESIMKERED 1148
Cdd:PTZ00121 1797 DKKIKDIFDNFANIIEGGKEGNLVINDSKEMED 1829
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
376-921 |
6.72e-13 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 74.01 E-value: 6.72e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 376 KLHELEKENLQLKAKLHDMEMERDMDRKKIE---ELMEENMTLEMAQKQSMdeslhlgweLEQISRTSELAEAPQKSLgH 452
Cdd:pfam05557 3 ELIESKARLSQLQNEKKQMELEHKRARIELEkkaSALKRQLDRESDRNQEL---------QKRIRLLEKREAEAEEAL-R 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 453 EVNELTSSKLLKLEMENQSL---TKTVEELRSTADSAAGSTSKiLKVEKENQRLNKKVEILENEIIQEKQSLQ--NCQNL 527
Cdd:pfam05557 73 EQAELNRLKKKYLEALNKKLnekESQLADAREVISCLKNELSE-LRRQIQRAELELQSTNSELEELQERLDLLkaKASEA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 528 SkdlmKEKAQLEKTIETLRENsERQIKILEQENEhlNQTVSSLRQRSQISAEARVKDIEKENKILHESIK---ETCGKLS 604
Cdd:pfam05557 152 E----QLRQNLEKQQSSLAEA-EQRIKELEFEIQ--SQEQDSEIVKNSKSELARIPELEKELERLREHNKhlnENIENKL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 605 KIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKN 684
Cdd:pfam05557 225 LLKEEVEDLKRKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSSLTS 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 685 LTFQLES----LEKENSQLDEENLELRRSVESLKCASMRMA-QLQLENKELESEKEQLR---KGLELMRASFKKTERLEV 756
Cdd:pfam05557 305 SARQLEKarreLEQELAQYLKKIEDLNKKLKRHKALVRRLQrRVLLLTKERDGYRAILEsydKELTMSNYSPQLLERIEE 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 757 SYQGLdtenQRLQKALENSNKKIQQLESEL-------QDLEMENQTL--QKSLEELKISSKRLEQLEKENKSLEQETSQL 827
Cdd:pfam05557 385 AEDMT----QKMQAHNEEMEAQLSVAEEELggykqqaQTLERELQALrqQESLADPSYSKEEVDSLRRKLETLELERQRL 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 828 EKDKKQLEKENKR--LRQQAEIKDT---------TLEENNVKIGNLEKenktLFKEINVYKEscvRLKELEKENKELVK- 895
Cdd:pfam05557 461 REQKNELEMELERrcLQGDYDPKKTkvlhlsmnpAAEAYQQRKNQLEK----LQAEIERLKR---LLKKLEDDLEQVLRl 533
|
570 580
....*....|....*....|....*....
gi 1390011543 896 ---RATIDIKTLVTLREDLVSEKLKTQQM 921
Cdd:pfam05557 534 petTSTMNFKEVLDLRKELESAELKNQRL 562
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
497-1073 |
1.33e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 73.43 E-value: 1.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ--RS 574
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARleQD 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 575 QISAEARVKDIEKENKILHESIKEtcgklskIEFEKRQMKKELELYKEKGERAE-ELENELNHLGKENELLQKKITNLKI 653
Cdd:COG1196 304 IARLEERRRELEERLEELEEELAE-------LEEELEELEEELEELEEELEEAEeELEEAEAELAEAEEALLEAEAELAE 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 654 TCEKLETLEQENSELERENRKFKKTLdsfKNLTFQLESLEKENSQLDEENLELRRSVESLkcasmRMAQLQLENKELESE 733
Cdd:COG1196 377 AEEELEELAEELLEALRAAAELAAQL---EELEEAEEALLERLERLEEELEELEEALAEL-----EEEEEEEEEALEEAA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 734 KEQLRKGLELMRASFKKTERLEVsyqgLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQL 813
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEE----AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 814 EK--------------ENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENnvKIGNLEKENKTLFKEINVYKES 879
Cdd:COG1196 525 AVavligveaayeaalEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLD--KIRARAALAAALARGAIGAAVD 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 880 CVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQqmNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRykLLES 959
Cdd:COG1196 603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL--AGRLREVTLEGEGGSAGGSLTGGSRRELLAAL--LEAE 678
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 960 KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSsipvsgeddkwgRESQEATR 1039
Cdd:COG1196 679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL------------EELLEEEE 746
|
570 580 590
....*....|....*....|....*....|....
gi 1390011543 1040 ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Cdd:COG1196 747 LLEEEALEELPEPPDLEELERELERLEREIEALG 780
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
252-877 |
2.38e-12 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 72.69 E-value: 2.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSR 331
Cdd:TIGR00618 250 EAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMK 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 332 YKERLHDiefyKARVEELKEDNQVLLETKTMLEDQLE---GTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEEL 408
Cdd:TIGR00618 330 RAAHVKQ----QSSIEEQRRLLQTLHSQEIHIRDAHEvatSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDIL 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 409 MEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEM-----ENQSLTKTVEELRSTA 483
Cdd:TIGR00618 406 QREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESaqslkEREQQLQTKEQIHLQE 485
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 484 DSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE--NSER-QIKILEQEN 560
Cdd:TIGR00618 486 TRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHqlTSERkQRASLKEQM 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 561 EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKK------ELELYKEKGERAEELENEL 634
Cdd:TIGR00618 566 QEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKlqpeqdLQDVRLHLQQCSQELALKL 645
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 635 NHLGKENELLQKKitnlKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEEN---LELRRSVE 711
Cdd:TIGR00618 646 TALHALQLTLTQE----RVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELEthiEEYDREFN 721
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 712 SLKCASMRM-----AQLQLENKELESEKEQLRKGL-ELMRASFKKTERLEVSYQgLDTENQRLQKALENSNKKIQQLESE 785
Cdd:TIGR00618 722 EIENASSSLgsdlaAREDALNQSLKELMHQARTVLkARTEAHFNNNEEVTAALQ-TGAELSHLAAEIQFFNRLREEDTHL 800
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 786 LQDLEMENQTLQKSLEELKISS-----KRLEQ----LEKENKSLEQETSQLEKD---KKQLEKENKRLRQQAEIKDTTLE 853
Cdd:TIGR00618 801 LKTLEAEIGQEIPSDEDILNLQcetlvQEEEQflsrLEEKSATLGEITHQLLKYeecSKQLAQLTQEQAKIIQLSDKLNG 880
|
650 660
....*....|....*....|....
gi 1390011543 854 ENNVKIGNLEKENKTLFKEINVYK 877
Cdd:TIGR00618 881 INQIKIQFDGDALIKFLHEITLYA 904
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
257-836 |
2.65e-12 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 71.98 E-value: 2.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDEL-DALREKAVRVDKLESELSRYKER 335
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLeKEKLNIQKNIDKIKNKLLKLELL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 336 LHDIEFY-------KARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDMDRKK 404
Cdd:TIGR04523 203 LSNLKKKiqknkslESQISELKKQNNQLKDNIEKKQQEINEKTTEisntQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 405 IEELMEENMTLEMA-----QKQSMDESLHLGWELEQISRT-----SELAEAPQK--SLGHEVNELTSSKLlKLEMENQSL 472
Cdd:TIGR04523 283 IKELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKleeiqNQISQNNKIisQLNEQISQLKKELT-NSESENSEK 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 473 TKTVEElrstadsaagSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQ 552
Cdd:TIGR04523 362 QRELEE----------KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL----EKE 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 553 IKILEQENEHLNQTVSSLRqrSQISA-EARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELelyKEKGERAEELE 631
Cdd:TIGR04523 428 IERLKETIIKNNSEIKDLT--NQDSVkELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL---KSKEKELKKLN 502
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 632 NELNHLGKENELLQKKITNLKitcEKLETLEQENSELERENRKFKKTLDSfKNLTFQLESLEKENSQLDEENLELRRSVE 711
Cdd:TIGR04523 503 EEKKELEEKVKDLTKKISSLK---EKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKEIEELKQTQK 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 712 SLKCASmrmAQLQLENKELESEKEQLRKGLELMRASF----KKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQ 787
Cdd:TIGR04523 579 SLKKKQ---EEKQELIDQKEKEKKDLIKEIEEKEKKIssleKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 788 -------DLEMENQTLQKSLEEL---------------------KISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:TIGR04523 656 eirnkwpEIIKKIKESKTKIDDIielmkdwlkelslhykkyitrMIRIKDLPKLEEKYKEIEKELKKLDEFSKELEN 732
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
628-1076 |
3.02e-12 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 71.72 E-value: 3.02e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 628 EELENELNHLGKENEllQKKITNLKitceKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Cdd:COG4717 49 ERLEKEADELFKPQG--RKPELNLK----ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 708 RSVESLkcasmrmaQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKI-QQLESEL 786
Cdd:COG4717 123 KLLQLL--------PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEEL 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 787 QDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEkDKKQLEKENKRLRQQAEI------------KDTTLEE 854
Cdd:COG4717 195 QDLAEELEELQQRLAELE---EELEEAQEELEELEEELEQLE-NELEAAALEERLKEARLLlliaaallallgLGGSLLS 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 855 NNVKIGN---------------LEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQ 919
Cdd:COG4717 271 LILTIAGvlflvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQ 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 920 QMNNDLEKLTHELEKIGLNKER--LLHDEQSTDDSRYkllESKLEstLKKSLEIKEEKIAALEARLEESTNYNQ------ 991
Cdd:COG4717 351 ELLREAEELEEELQLEELEQEIaaLLAEAGVEDEEEL---RAALE--QAEEYQELKEELEELEEQLEELLGELEelleal 425
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 992 ---QLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQ 1068
Cdd:COG4717 426 deeELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEEA 505
|
....*...
gi 1390011543 1069 LKQLETQN 1076
Cdd:COG4717 506 REEYREER 513
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
608-1010 |
6.69e-12 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 70.57 E-value: 6.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 608 FEKRQMKKELELYKEKG-------ERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKtLD 680
Cdd:COG4717 47 LLERLEKEADELFKPQGrkpelnlKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEK-LL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 681 SFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRAsfKKTERLEVSYQG 760
Cdd:COG4717 126 QLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE--EELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 761 LDTENQRLQKALENSNKKIQQLESELQDLE--MENQTLQKSLEELKISSK------------------------------ 808
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQLEneLEAAALEERLKEARLLLLiaaallallglggsllsliltiagvlflvl 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 809 -----RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESC--V 881
Cdd:COG4717 284 gllalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEeeL 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 882 RLKELEKENKELVKRAtiDIKTLVTLREdLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD-DSRYKLLESK 960
Cdd:COG4717 364 QLEELEQEIAALLAEA--GVEDEEELRA-ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEElEEELEELEEE 440
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 1390011543 961 LEStLKKSLEIKEEKIAALEARLE--ESTNYNQQLRHELKTVKKNYEALKQR 1010
Cdd:COG4717 441 LEE-LEEELEELREELAELEAELEqlEEDGELAELLQELEELKAELRELAEE 491
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
182-801 |
7.49e-12 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 70.92 E-value: 7.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 182 SQEDIEPLLKNMVSHLRRLIDErdeHSETIVELSEERDGvhflphASSSAQSPCGSPGMKRTESRQHLSV---ELADAKA 258
Cdd:pfam15921 254 SQNKIELLLQQHQDRIEQLISE---HEVEITGLTEKASS------ARSQANSIQSQLEIIQEQARNQNSMymrQLSDLES 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 259 KIRRLRQEL-----------EEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARS--ARMYRDELDALREK------- 318
Cdd:pfam15921 325 TVSQLRSELreakrmyedkiEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKllADLHKREKELSLEKeqnkrlw 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 319 ------AVRVDKLESELSrykERLHDIEFYKARVEELKEdnqvllETKTMLEDQLEGTRARSDKLHELEKENLQLkaklh 392
Cdd:pfam15921 405 drdtgnSITIDHLRRELD---DRNMEVQRLEALLKAMKS------ECQGQMERQMAAIQGKNESLEKVSSLTAQL----- 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 393 dmEMERDMDRKKIEELMEENMTLEMAQKQSMDeslhLGWELEQISRTSELAEApqkslghEVNELTSSKLLKLEmENQSL 472
Cdd:pfam15921 471 --ESTKEMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERAIEATNA-------EITKLRSRVDLKLQ-ELQHL 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 473 TKTVEELRStadsaAGSTSKILKVEKENQrlNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETlRENSERQ 552
Cdd:pfam15921 537 KNEGDHLRN-----VQTECEALKLQMAEK--DKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND-RRLELQE 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 553 IKILEQENEhlnqtvSSLRQrsqisAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKekgeraeeleN 632
Cdd:pfam15921 609 FKILKDKKD------AKIRE-----LEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSR----------N 667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 633 ELNHLGKENELLQKKITN----LKITCEKLE-TLEQENSELERENRKFKK-----------TLDSFKNLTF---QLESLE 693
Cdd:pfam15921 668 ELNSLSEDYEVLKRNFRNkseeMETTTNKLKmQLKSAQSELEQTRNTLKSmegsdghamkvAMGMQKQITAkrgQIDALQ 747
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 694 KENSQLDEENLELRRSVESLKCASMRMAQlqlENKELESEKEQLRKGLELMRAsfkKTERLEVSYQGLDTENQRLQKALE 773
Cdd:pfam15921 748 SKIQFLEEAMTNANKEKHFLKEEKNKLSQ---ELSTVATEKNKMAGELEVLRS---QERRLKEKVANMEVALDKASLQFA 821
|
650 660
....*....|....*....|....*...
gi 1390011543 774 NSNKKIQQLESELQDLEMENQTLQKSLE 801
Cdd:pfam15921 822 ECQDIIQRQEQESVRLKLQHTLDVKELQ 849
|
|
| HkD_Hook2 |
cd22227 |
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a ... |
18-163 |
7.51e-12 |
|
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a microtubule-binding protein that contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook2 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411798 Cd Length: 150 Bit Score: 64.90 E-value: 7.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 18 LVTWVKTFGPLAAGNgtnldEYVALVDGVFLNQVMLQINP----KSESQRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:cd22227 6 LLTWLQTFQVPSPCS-----SYQDLTSGVAIAQVLNRIDPswfnEAWLGRIKEDTGDNWRLKVSNLKKILQSLLEYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1390011543 94 L-QQLIMMPLPDILIIGKnpFSEqgTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22227 81 LgHQVSEDHLPDVNLIGE--FSD--DTELGKLLQLVLGCAISCEKKQEHIQQIMTLEESVQHVVMEAIQEL 147
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
264-670 |
8.51e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.86 E-value: 8.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 264 RQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARmyrdelDALREKAVRVDKLESELSRYKERlhdIEFYK 343
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR------KELEELSRQISALRKDLARLEAE---VEQLE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 344 ARVEELKEDNQVLLETKTMLEDQLEGTRarsDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTL--EMAQKQ 421
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAE---EELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLneEAANLR 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 422 SMDESLH-----LGWELEQISRTSELAEAPQKSLGHEVNELTSSkLLKLEMENQSLTKTVEELRSTADSAagstskilkv 496
Cdd:TIGR02168 824 ERLESLErriaaTERRLEDLEEQIEELSEDIESLAAEIEELEEL-IEELESELEALLNERASLEEALALL---------- 892
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 497 EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN-SERQIKILEQENEHLNQTVSSLRQrsq 575
Cdd:TIGR02168 893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKIEDDEEE--- 969
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 576 isAEARVKDIEKEnkilhesIKEtcgkLSKIEFEKrqmkkeLELYKEKGERAEELENELNHLGKENELLQKKITNLKITC 655
Cdd:TIGR02168 970 --ARRRLKRLENK-------IKE----LGPVNLAA------IEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREA 1030
|
410
....*....|....*..
gi 1390011543 656 EK--LETLEQENSELER 670
Cdd:TIGR02168 1031 RErfKDTFDQVNENFQR 1047
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
263-586 |
1.37e-11 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 69.33 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 263 LRQELEEKTEQLL-------DCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSRYKER 335
Cdd:pfam05622 64 LQKQLEQLQEENFrletardDYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEMDILRESSDKVKKLEATVETYKKK 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 336 LHDIEFYKARVEELKEDNQVLLETKTMLED----------QLEGTRARSDKLH-----------ELEKENLQLKAKLHDM 394
Cdd:pfam05622 144 LEDLGDLRRQVKLLEERNAEYMQRTLQLEEelkkanalrgQLETYKRQVQELHgklseeskkadKLEFEYKKLEEKLEAL 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 395 EMERDMDRKKIEELMEENMTLEMAQKQSmDESLHLGWELEQISRTSELAEAPQKSLghEVNEltssKLLKLEMENQSLTK 474
Cdd:pfam05622 224 QKEKERLIIERDTLRETNEELRCAQLQQ-AELSQADALLSPSSDPGDNLAAEIMPA--EIRE----KLIRLQHENKMLRL 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 475 TVE--------ELRSTADSAAGSTSKIlkvEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLR 546
Cdd:pfam05622 297 GQEgsyrerltELQQLLEDANRRKNEL---ETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLEKLH 373
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1390011543 547 E-NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Cdd:pfam05622 374 EaQSELQKKKEQIEELEPKQDSNLAQKIDELQEALRKKDED 414
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
201-669 |
1.54e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 69.68 E-value: 1.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 201 IDERDEHSETIVELSEERDGVhflphasssaqspcgspGMKRTESRQHLSVELADAKAkIRRLRQELEEKTEQlldCKQE 280
Cdd:PRK02224 271 EREREELAEEVRDLRERLEEL-----------------EEERDDLLAEAGLDDADAEA-VEARREELEDRDEE---LRDR 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 281 LEQIEVELKRLQQENMNLLSDARSArmyRDELDALREKAvrvDKLESELSRYKErlhDIEFYKARVEELKEDNQVLLETK 360
Cdd:PRK02224 330 LEECRVAAQAHNEEAESLREDADDL---EERAEELREEA---AELESELEEARE---AVEDRREEIEELEEEIEELRERF 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 361 TMLEDQLEGTRARSDKLHElEKENlqlkakLHDMEMERDMDRKKIEELMEENMTLEMAQK-----QSMDESLHLGWELEQ 435
Cdd:PRK02224 401 GDAPVDLGNAEDFLEELRE-ERDE------LREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEGSPHVETIEED 473
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 436 ISRTSELaEAPQKSLGHEVNEL-----TSSKLLKLEMENQSL---TKTVEELRSTA-DSAAGSTSKILKVEKENQRLNKK 506
Cdd:PRK02224 474 RERVEEL-EAELEDLEEEVEEVeerleRAEDLVEAEDRIERLeerREDLEELIAERrETIEEKRERAEELRERAAELEAE 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 507 VEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIleqenEHLNQTVSSLRQRSQISAEarVKDIE 586
Cdd:PRK02224 553 AEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAI-----ADAEDEIERLREKREALAE--LNDER 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 587 KEN-KILHESIKETCGKLSKIEFEK-RQMKKELELYKEK-GERAEELENELNHL-----GKENEL-----LQKKITNLKI 653
Cdd:PRK02224 626 RERlAEKRERKRELEAEFDEARIEEaREDKERAEEYLEQvEEKLDELREERDDLqaeigAVENELeeleeLRERREALEN 705
|
490
....*....|....*.
gi 1390011543 654 TCEKLETLEQENSELE 669
Cdd:PRK02224 706 RVEALEALYDEAEELE 721
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
257-1377 |
2.11e-11 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 69.70 E-value: 2.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 257 KAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNL----LSDARSARMYRDELDALReKAVRVDKLESELSRY 332
Cdd:TIGR01612 557 KKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYInklkLELKEKIKNISDKNEYIK-KAIDLKKIIENNNAY 635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 333 KERLHDIEFYKArVEELKEDNQVLLETKTMLEDQLEGTRAR-----SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEE 407
Cdd:TIGR01612 636 IDELAKISPYQV-PEHLKNKDKIYSTIKSELSKIYEDDIDAlynelSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQN 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 408 LMEENMTLEMAQKQSMDESL---------HLGWEL-EQISRTSELAEAPQKSLGHEVNELTS---------SKL--LKLE 466
Cdd:TIGR01612 715 METATVELHLSNIENKKNELldiiveikkHIHGEInKDLNKILEDFKNKEKELSNKINDYAKekdelnkykSKIseIKNH 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 467 MENQSLTKTV--EELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKD-LMKEKAQLEKTIE 543
Cdd:TIGR01612 795 YNDQINIDNIkdEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEkIDSEHEQFAELTN 874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 544 TLR-ENSERQIKILEQE----NEHLNQTVSSLRQRSQ-ISAEARVKDIEKENKILHESIKETCGKLSKIefeKRQMKKEL 617
Cdd:TIGR01612 875 KIKaEISDDKLNDYEKKfndsKSLINEINKSIEEEYQnINTLKKVDEYIKICENTKESIEKFHNKQNIL---KEILNKNI 951
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 618 ELYKEKGERAEELENELnhlgkENELLQKKITNLKITCE-KLETLEQENSELERENRKFKKTLDSFKN--LTFQLESLEK 694
Cdd:TIGR01612 952 DTIKESNLIEKSYKDKF-----DNTLIDKINELDKAFKDaSLNDYEAKNNELIKYFNDLKANLGKNKEnmLYHQFDEKEK 1026
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 695 ENSQLDEENLELRRSVESLKCA---SMRMAQLQLEN---KELESEKEQLRKGLELMRASFKKTERLEVSYQGLD------ 762
Cdd:TIGR01612 1027 ATNDIEQKIEDANKNIPNIEIAihtSIYNIIDEIEKeigKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDfgkeen 1106
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 763 ----TENQRLQKALENSNKKIQQLESELQDLEM-------ENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:TIGR01612 1107 ikyaDEINKIKDDIKNLDQKIDHHIKALEEIKKksenyidEIKAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKK 1186
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 832 KQLEKENKRLRQQAEIK--DTTLEE-NNVKIGNLEKENKTLFKEIN-VYKESCVRLKELEKENKEL--VKRATIDIKTLV 905
Cdd:TIGR01612 1187 NIYDEIKKLLNEIAEIEkdKTSLEEvKGINLSYGKNLGKLFLEKIDeEKKKSEHMIKAMEAYIEDLdeIKEKSPEIENEM 1266
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 906 TLREDLVSEkLKTQQMNNDLEKLTHELEKiglnkerllHDEQSTDDSRYKLLESKLESTLKKSL-EIKEEkiaaLEARLE 984
Cdd:TIGR01612 1267 GIEMDIKAE-METFNISHDDDKDHHIISK---------KHDENISDIREKSLKIIEDFSEESDInDIKKE----LQKNLL 1332
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 985 ESTNYNQQLRHELKTVKKNYEALKQRQdeermVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQA 1064
Cdd:TIGR01612 1333 DAQKHNSDINLYLNEIANIYNILKLNK-----IKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSK 1407
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1065 LKTqlkQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ--LLIQQSSLENE---N 1139
Cdd:TIGR01612 1408 IES---TLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQhiLKIKKDNATNDhdfN 1484
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1140 ESIMKERED----LKSLYDALIKDHEKLELLHERQASEYESLISKHGTLK------SAHKNLEVEHKDLEDRYNQLLKQK 1209
Cdd:TIGR01612 1485 INELKEHIDkskgCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAiknkfaKTKKDSEIIIKEIKDAHKKFILEA 1564
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1210 GQLEDLEKMIKTEQEKMLLESKNHEvvaSEYKKLCGENDRLNYTYSQLLKETEILQMDHKNLKSVLN-NSKLEQTRLEAE 1288
Cdd:TIGR01612 1565 EKSEQKIKEIKKEKFRIEDDAAKND---KSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESiEKKISSFSIDSQ 1641
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1289 FSKLKEQYQQLDITSTKLnnqcELLSQLKGNLEEENRHlLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLN--EL 1366
Cdd:TIGR01612 1642 DTELKENGDNLNSLQEFL----ESLKDQKKNIEDKKKE-LDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANkeEI 1716
|
1210
....*....|.
gi 1390011543 1367 RRQKEKLEEKI 1377
Cdd:TIGR01612 1717 ESIKELIEPTI 1727
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
770-1378 |
2.39e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 68.94 E-value: 2.39e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 770 KALENSNKKIQQLESELQDLEMENQTLQKSLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqaeikd 849
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPEL---REELEKLEKEVKELEELKEEIEELEKELESLEGSKR------- 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 850 tTLEEnnvKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKratidiktLVTLREDLVSEKlktqqmnNDLEKLT 929
Cdd:PRK03918 256 -KLEE---KIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK--------LSEFYEEYLDEL-------REIEKRL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 930 HELEKIGLNKERLLHDEQStddsryklLESKLESTLKKSLEIKEEKiaaleARLEEStnynQQLRHELKTVKKNYEALKQ 1009
Cdd:PRK03918 317 SRLEEEINGIEERIKELEE--------KEERLEELKKKLKELEKRL-----EELEER----HELYEEAKAKKEELERLKK 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1010 RqdeermvqssipvsgeddKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA--QILALQ 1087
Cdd:PRK03918 380 R------------------LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakGKCPVC 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1088 RQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENEnesIMKERE--DLKSLYDALIKDHEKLEL 1165
Cdd:PRK03918 442 GRELTEEHRKELLEEYTAEL----KRIEKELKEIEEKERKLRKELRELEKV---LKKESEliKLKELAEQLKELEEKLKK 514
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1166 LH----ERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKmikteqEKMLLESKNHEVVASEYK 1241
Cdd:PRK03918 515 YNleelEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEE------ELAELLKELEELGFESVE 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1242 KLCGENDRLNYTYSQLLKeteilqmdhknLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLE 1321
Cdd:PRK03918 589 ELEERLKELEPFYNEYLE-----------LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS 657
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1390011543 1322 EEN----RHLLDQIQTLMLQNRTLLEQNMESKDlfhveqrQYIDKLNELRRQKEKLEEKIM 1378
Cdd:PRK03918 658 EEEyeelREEYLELSRELAGLRAELEELEKRRE-------EIKKTLEKLKEELEEREKAKK 711
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
346-878 |
3.18e-11 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 68.77 E-value: 3.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 346 VEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEnMTLEMAQKQSMDE 425
Cdd:PRK01156 161 INSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIE-YNNAMDDYNNLKS 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 426 SLH-LGWELEQISR-TSELAEAPQK--SLGHEVNELTSSKLLKLEMENQSLTKTVEELRS--TADSAAGSTSKILK-VEK 498
Cdd:PRK01156 240 ALNeLSSLEDMKNRyESEIKTAESDlsMELEKNNYYKELEERHMKIINDPVYKNRNYINDyfKYKNDIENKKQILSnIDA 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 499 ENQRLN---KKVEILE---NEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrENSERQIKILEQENEHLNQTVSSLRQ 572
Cdd:PRK01156 320 EINKYHaiiKKLSVLQkdyNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSI-ESLKKKIEEYSKNIERMSAFISEILK 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 573 RSQISAEARVKDIEKENKilheSIKETCGKLSKIEFEKRQMKKELE-----------------------------LYKEK 623
Cdd:PRK01156 399 IQEIDPDAIKKELNEINV----KLQDISSKVSSLNQRIRALRENLDelsrnmemlngqsvcpvcgttlgeeksnhIINHY 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 624 GERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSE--------LERENRKFKKTLDSFKNLTFQLESLEKE 695
Cdd:PRK01156 475 NEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSIneynkiesARADLEDIKIKINELKDKHDKYEEIKNR 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 696 NSQLDEENLELRRSvESLKCASMRmAQLQLENkeLESEKEQLRKGLELMRasfKKTERLEVSYQGLDTENQRLQKALENS 775
Cdd:PRK01156 555 YKSLKLEDLDSKRT-SWLNALAVI-SLIDIET--NRSRSNEIKKQLNDLE---SRLQEIEIGFPDDKSYIDKSIREIENE 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 776 NKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE-------NKRLRQQAEIK 848
Cdd:PRK01156 628 ANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKAlddakanRARLESTIEIL 707
|
570 580 590
....*....|....*....|....*....|...
gi 1390011543 849 DTTLEENNVKIGNLEKE---NKTLFKEINVYKE 878
Cdd:PRK01156 708 RTRINELSDRINDINETlesMKKIKKAIGDLKR 740
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
203-838 |
4.23e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 68.63 E-value: 4.23e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 203 ERDEHSETIVELSEERDGVHFLPHASSSAQSPCGSPGMKRTES-RQHLSVELADAKAKIRRLRQELEE--KTEQLLDCKQ 279
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEkKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAE 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 280 ELEQIEVELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLESELSRYKERLHDIEFYKARVEELK----EDNQ 354
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAeAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKkkaeEDKK 1405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 355 VLLETKTMLEDQLEGTRARsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELE 434
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAK--KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 435 QISRTSELAEAPQKSlghevneltSSKLLKLEMENqsltKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEI 514
Cdd:PTZ00121 1484 KADEAKKKAEEAKKK---------ADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 515 IQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIkileqENEHLNQTVSSLRQRSQISAEARVKdiEKENKILHE 594
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA-----EEARIEEVMKLYEEEKKMKAEEAKK--AEEAKIKAE 1623
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 595 SIKetcgklsKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRK 674
Cdd:PTZ00121 1624 ELK-------KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 675 FKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLR--KGLELMRASFKKTE 752
Cdd:PTZ00121 1697 EAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAhlKKEEEKKAEEIRKE 1776
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 753 RLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRlEQLEKENKSLEqETSQLEKDKK 832
Cdd:PTZ00121 1777 KEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIK-EVADSKNMQLE-EADAFEKHKF 1854
|
....*.
gi 1390011543 833 QLEKEN 838
Cdd:PTZ00121 1855 NKNNEN 1860
|
|
| HkD_Hook1 |
cd22225 |
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a ... |
18-163 |
5.66e-11 |
|
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a microtubule-binding protein required for spermatid differentiation. It is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411796 Cd Length: 150 Bit Score: 62.56 E-value: 5.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 18 LVTWVKTFGPLAAGNGTNldeyvALVDGVFLNQVMLQINPK--SES--QRVNKKVNNDASLRIHNLSILVKQIKFYYQET 93
Cdd:cd22225 5 LIIWLQTFNTAAPCQTVQ-----DLTSGVAMAQVLHQIDSSwfDESwlSRIKEDVGDNWRIKMSNLKKILQGIVDYYHEF 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1390011543 94 L-QQLIMMPLPDIliigkNPFSEQGTE-EVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22225 80 LdQQISEFLLPDL-----NRIAEHSDPvELGRLLQLILGCAVNCEKKQEHIQNIMTLEESVQHVVMTAIQEL 146
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
688-1218 |
1.24e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 66.60 E-value: 1.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 688 QLESLEKENSQLDEEnlELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLElmrasfKKTERLEvSYQGLDTENQR 767
Cdd:PRK02224 185 QRGSLDQLKAQIEEK--EEKDLHERLNGLESELAELDEEIERYEEQREQARETRD------EADEVLE-EHEERREELET 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 768 LQKALENSNKKIQQLESELQDLEMENQTLQKSLEEL------------------KISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:PRK02224 256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELeeerddllaeaglddadaEAVEARREELEDRDEELRDRLEECRV 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 830 DKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKELVKR---ATIDIKTLVT 906
Cdd:PRK02224 336 AAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRRE---EIEELEEEIEELRERfgdAPVDLGNAED 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD------EQSTDDS-RYKLLESKLE--STLKKSLEIKEEKIA 977
Cdd:PRK02224 413 FLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecGQPVEGSpHVETIEEDRErvEELEAELEDLEEEVE 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 978 ALEARLEESTNYnQQLRHELKTVKKNYEALKQRQDEER--------MVQSSIPVSGEDDKWGRESQEATRELlkvKDRLI 1049
Cdd:PRK02224 493 EVEERLERAEDL-VEAEDRIERLEERREDLEELIAERRetieekreRAEELRERAAELEAEAEEKREAAAEA---EEEAE 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1050 EVERNNATLQAEKQALKTQLKQLETQnNNLQAQILALQRQTVSLQEQNTTLQTQNAKlqvENSTLNSQSTSlmnqnaqll 1129
Cdd:PRK02224 569 EAREEVAELNSKLAELKERIESLERI-RTLLAAIADAEDEIERLREKREALAELNDE---RRERLAEKRER--------- 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1130 IQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQaseyESLISKHGTLKSAHKNLEV---EHKDLEDRYNQLL 1206
Cdd:PRK02224 636 KRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREER----DDLQAEIGAVENELEELEElreRREALENRVEALE 711
|
570
....*....|..
gi 1390011543 1207 KQKGQLEDLEKM 1218
Cdd:PRK02224 712 ALYDEAEELESM 723
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
605-1241 |
1.31e-10 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 66.67 E-value: 1.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 605 KIEFEKRQMKKELELYKEK-GERAEELENELNHLGKENELLQKKITNLKITC----EKLETLEQENSELERE----NRKF 675
Cdd:pfam05483 113 KIIEAQRKAIQELQFENEKvSLKLEEEIQENKDLIKENNATRHLCNLLKETCarsaEKTKKYEYEREETRQVymdlNNNI 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 676 KKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELES-EKEQLRKGLE-LMRASFKKTER 753
Cdd:pfam05483 193 EKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQItEKENKMKDLTfLLEESRDKANQ 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 754 LEvsyqgldtENQRLQ-KALENSNKKIQQLESELQDLEMENQ---TLQKSLEE-LKISSKRLEQLEKENKSLEQETSQLE 828
Cdd:pfam05483 273 LE--------EKTKLQdENLKELIEKKDHLTKELEDIKMSLQrsmSTQKALEEdLQIATKTICQLTEEKEAQMEELNKAK 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 829 KDKKQLEKENKRLRQQAEikdTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELeKENKELVKRatiDIKTLVTLR 908
Cdd:pfam05483 345 AAHSFVVTEFEATTCSLE---ELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKF-KNNKEVELE---ELKKILAED 417
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 909 EDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD--EQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEES 986
Cdd:pfam05483 418 EKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDleIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKL 497
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 987 TNYNQQLRHE-----LKTVKKNYEALKQRQDEERMVQSsIPVSGEDDKWGRESQEATRELLK-----VKDRLIEVERNNA 1056
Cdd:pfam05483 498 LLENKELTQEasdmtLELKKHQEDIINCKKQEERMLKQ-IENLEEKEMNLRDELESVREEFIqkgdeVKCKLDKSEENAR 576
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1057 TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ----TQNAKLQVENSTLNSQSTSL---------MN 1123
Cdd:pfam05483 577 SIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKkkgsAENKQLNAYEIKVNKLELELasakqkfeeII 656
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1124 QNAQLLIQQSSLENENesIMKEREDLKSLYDALIKDHEKLEL-----------LHERQASEYESLISKHGTLKSAHKNLE 1192
Cdd:pfam05483 657 DNYQKEIEDKKISEEK--LLEEVEKAKAIADEAVKLQKEIDKrcqhkiaemvaLMEKHKHQYDKIIEERDSELGLYKNKE 734
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 1193 VEHK--------DLEDRYNQLLKQKGQLEdlekMIKTEQEKMLLESKNHEVVASEYK 1241
Cdd:pfam05483 735 QEQSsakaaleiELSNIKAELLSLKKQLE----IEKEEKEKLKMEAKENTAILKDKK 787
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
259-750 |
1.62e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 66.33 E-value: 1.62e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 259 KIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAvrvdKLESELSRYKERLHD 338
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELE----ALEAELAELPERLEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 339 IEFYKARVEELKEDNQVLLETKTMLEDQLEgtRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEmA 418
Cdd:COG4717 151 LEERLEELRELEEELEELEAELAELQEELE--ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE-E 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 419 QKQSMDESLHLGWELEQISRTSELAeapqkslghevneLTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILkvek 498
Cdd:COG4717 228 ELEQLENELEAAALEERLKEARLLL-------------LIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLF---- 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 499 enqRLNKKVEILENEIIQEKQSLQNCQNLskdlmkEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA 578
Cdd:COG4717 291 ---LLLAREKASLGKEAEELQALPALEEL------EEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEE 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 579 EARVKDIEKENKILHESIKETcgklSKIEFEKRQmkKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITcEKL 658
Cdd:COG4717 362 ELQLEELEQEIAALLAEAGVE----DEEELRAAL--EQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELE-EEL 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 659 ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEK-ENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQL 737
Cdd:COG4717 435 EELEEELEELEEELEELREELAELEAELEQLEEDGElAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
|
490
....*....|...
gi 1390011543 738 RKGLELMRASFKK 750
Cdd:COG4717 515 PPVLERASEYFSR 527
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
305-1031 |
1.70e-10 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 66.53 E-value: 1.70e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 305 ARMYRDELDALREKAVRVDKLESELSRYKERLHD-----IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379
Cdd:TIGR00618 182 ALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDtyherKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQL 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 380 L-----EKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGweleqiSRTSELAEAPQKSLGHEV 454
Cdd:TIGR00618 262 LkqlraRIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQ------SKMRSRAKLLMKRAAHVK 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 455 NELTSSKLLKLEmenQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEiiqeKQSLQNCQNLSKDLMKE 534
Cdd:TIGR00618 336 QQSSIEEQRRLL---QTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTL----TQKLQSLCKELDILQRE 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 535 KAQLEktIETLRENSERQIKILEQENEHLNQTVSSLRQrsqISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMK 614
Cdd:TIGR00618 409 QATID--TRTSAFRDLQGQLAHAKKQQELQQRYAELCA---AAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHL 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 615 KELELYKEKGERAEEL-ENELNHLGKENELLQKK--ITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNltfQLES 691
Cdd:TIGR00618 484 QETRKKAVVLARLLELqEEPCPLCGSCIHPNPARqdIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERK---QRAS 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 692 LEKENSQLDEENLELRRSVESLKCASMRMAQL-QLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQK 770
Cdd:TIGR00618 561 LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNItVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQE 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 771 ALENSNKKIQQLESELQDLEMENQTLQKSLEELKisskrLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Cdd:TIGR00618 641 LALKLTALHALQLTLTQERVREHALSIRVLPKEL-----LASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEE 715
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 851 TLEENN-------VKIGNLEKENKTLFKEINVYKESC-VRLKELEKENKELVKRATIDIKTLVTLrEDLVSEklkTQQMN 922
Cdd:TIGR00618 716 YDREFNeienassSLGSDLAAREDALNQSLKELMHQArTVLKARTEAHFNNNEEVTAALQTGAEL-SHLAAE---IQFFN 791
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 923 NDLEKLTHELekiglnkerllhdeqstddsryKLLESKLESTLKKSLEIKE---EKIAALEARLEESTNYNQQLRHELKT 999
Cdd:TIGR00618 792 RLREEDTHLL----------------------KTLEAEIGQEIPSDEDILNlqcETLVQEEEQFLSRLEEKSATLGEITH 849
|
730 740 750
....*....|....*....|....*....|..
gi 1390011543 1000 VKKNYEALKQRQDEerMVQSSIPVSGEDDKWG 1031
Cdd:TIGR00618 850 QLLKYEECSKQLAQ--LTQEQAKIIQLSDKLN 879
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
241-570 |
2.01e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 66.24 E-value: 2.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 241 KRTESRQH---LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNllsdarsarmYRDELDALRE 317
Cdd:TIGR02169 696 ELRRIENRldeLSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN----------VKSELKELEA 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 318 kavRVDKLESELSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE----LEKENLQLKAKL 391
Cdd:TIGR02169 766 ---RIEELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLekeyLEKEIQELQEQR 842
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 392 HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQS 471
Cdd:TIGR02169 843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 472 LTK---------TVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILE---NEIIQEKQSLQNCQNLSKD----LMKEK 535
Cdd:TIGR02169 923 KAKlealeeelsEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEpvnMLAIQEYEEVLKRLDELKEkrakLEEER 1002
|
330 340 350
....*....|....*....|....*....|....*..
gi 1390011543 536 AQLEKTIETLrENSERQI--KILEQENEHLNQTVSSL 570
Cdd:TIGR02169 1003 KAILERIEEY-EKKKREVfmEAFEAINENFNEIFAEL 1038
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
305-1045 |
2.45e-10 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 65.90 E-value: 2.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 305 ARMYRDELDALREKAVRVDKLESELSRYKERLHDIEFYKARVEELKEDNQVL---LETKTMLEDQLEGTRARSDKLHELE 381
Cdd:pfam05483 81 SKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVslkLEEEIQENKDLIKENNATRHLCNLL 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 382 KENLQLKA-KLHDMEMERDMDRKKIEELME--ENMTL--EMAQKQSMDESLHLGWEL-EQISRTSELAEAPQKSLGHEVN 455
Cdd:pfam05483 161 KETCARSAeKTKKYEYEREETRQVYMDLNNniEKMILafEELRVQAENARLEMHFKLkEDHEKIQHLEEEYKKEINDKEK 240
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 456 ELTSSKLLKLEMENQ--SLTKTVEELRSTADSAAGSTskilKVEKEN-QRLNKKVEILENEIIQEKQSLQNCQNLSKDLM 532
Cdd:pfam05483 241 QVSLLLIQITEKENKmkDLTFLLEESRDKANQLEEKT----KLQDENlKELIEKKDHLTKELEDIKMSLQRSMSTQKALE 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 533 KEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLrqrsqisaEARVKDIEKENKILHESIKETCGKLSKIEFEKRQ 612
Cdd:pfam05483 317 EDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEF--------EATTCSLEELLRTEQQRLEKNEDQLKIITMELQK 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 613 MKKELE-LYKEKGERAEELENELNHLGKENELLQKKITNLKITcEKLETLEQENSELERENRKfkktldSFKNLTFQLES 691
Cdd:pfam05483 389 KSSELEeMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIA-EELKGKEQELIFLLQAREK------EIHDLEIQLTA 461
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 692 LEKENSQLDEENLELRRSVESLKCASMRMA----QLQLENKELESEKEQLRKGLELMRASFKKTERLEvsyqgldtenQR 767
Cdd:pfam05483 462 IKTSEEHYLKEVEDLKTELEKEKLKNIELTahcdKLLLENKELTQEASDMTLELKKHQEDIINCKKQE----------ER 531
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 768 LQKALENSNKKIQQLESELQDLEMEnqtLQKSLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Cdd:pfam05483 532 MLKQIENLEEKEMNLRDELESVREE---FIQKGDEVKC---KLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIEN 605
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 848 KDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLkELEKEN-----KELVKRATIDIKTLVTLREDLVSEKLKTQQMN 922
Cdd:pfam05483 606 KNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKL-ELELASakqkfEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIA 684
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 923 NDLEKLTHELEKIGLNKerllhdeqstdDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKK 1002
Cdd:pfam05483 685 DEAVKLQKEIDKRCQHK-----------IAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKA 753
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 1390011543 1003 NYEALKQRQDEERMvqssipvsgEDDKWGRESQEATRELLKVK 1045
Cdd:pfam05483 754 ELLSLKKQLEIEKE---------EKEKLKMEAKENTAILKDKK 787
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
456-877 |
3.35e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 65.17 E-value: 3.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 456 ELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEK--QSLQNCQNLSKDLMK 533
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 534 EKAQLEKTIETLRENsERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQM 613
Cdd:COG4717 147 RLEELEERLEELREL-EEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 614 KKELELYKEKGERAEELENE-------------LNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLD 680
Cdd:COG4717 226 EEELEQLENELEAAALEERLkearlllliaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAE 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 681 SFKNLTfQLESLEKE--NSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLR-KGLELMRASF--KKTERLE 755
Cdd:COG4717 306 ELQALP-ALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQlEELEQEIAALlaEAGVEDE 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 756 VSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKslEELKissKRLEQLEKENKSLEQETSQLEKDKKQLE 835
Cdd:COG4717 385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE--EELE---EELEELEEELEELEEELEELREELAELE 459
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1390011543 836 KENKRLRqqaeiKDTTLEENNVKIGNLEKENKTLFKEINVYK 877
Cdd:COG4717 460 AELEQLE-----EDGELAELLQELEELKAELRELAEEWAALK 496
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1036-1371 |
3.54e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 65.34 E-value: 3.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1036 EATRE-LLKVKDRLIEVERNNATL--QAEK----QALKTQLKQLEtqnnnlqAQILALQRQTVSLQeqnttLQTQNAKLQ 1108
Cdd:COG1196 182 EATEEnLERLEDILGELERQLEPLerQAEKaeryRELKEELKELE-------AELLLLKLRELEAE-----LEELEAELE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1109 VENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYEsliskhgTLKSAH 1188
Cdd:COG1196 250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE-------RLEELE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1189 KNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLNYTYSQLLKETEILQMDH 1268
Cdd:COG1196 323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1269 KNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLmLQNRTLLEQNMES 1348
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL-LEEAALLEAALAE 481
|
330 340
....*....|....*....|...
gi 1390011543 1349 KDLFHVEQRQYIDKLNELRRQKE 1371
Cdd:COG1196 482 LLEELAEAAARLLLLLEAEADYE 504
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
614-1229 |
8.19e-10 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 64.33 E-value: 8.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 614 KKELELYKEKGERaEELENELNHlgKENELLQKKITNLK-----ITCEKLETLEQENSELERENRKFKKTLDSFKNLTfq 688
Cdd:COG5022 821 KLQKTIKREKKLR-ETEEVEFSL--KAEVLIQKFGRSLKakkrfSLLKKETIYLQSAQRVELAERQLQELKIDVKSIS-- 895
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 689 leSLEKENSQLDEENLELRRSVESLkcasmRMAQLQLENKELESEKEQLRKGlELMRASFKKTERLEVSyQGLDTENQRL 768
Cdd:COG5022 896 --SLKLVNLELESEIIELKKSLSSD-----LIENLEFKTELIARLKKLLNNI-DLEEGPSIEYVKLPEL-NKLHEVESKL 966
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 769 QKA---LENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQA 845
Cdd:COG5022 967 KETseeYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILK 1046
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 846 EIKD----TTLEEN----NVKIGNLEKENKTLFK------EINVYKESCVRLKELEKENKELVKratiDIKTLVTLREDL 911
Cdd:COG5022 1047 PLQKlkglLLLENNqlqaRYKALKLRRENSLLDDkqlyqlESTENLLKTINVKDLEVTNRNLVK----PANVLQFIVAQM 1122
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 912 VSEKLKtQQMNNDLEKLTHELEKI--GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEekiAALEARLEESTNY 989
Cdd:COG5022 1123 IKLNLL-QEISKFLSQLVNTLEPVfqKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLYQS---ALYDEKSKLSSSE 1198
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 990 NQQLRHELKTVKKNYEALKQRQDEERMVQS--------SIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAE 1061
Cdd:COG5022 1199 VNDLKNELIALFSKIFSGWPRGDKLKKLISegwvpteySTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLE 1278
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1062 KQALKTQLKQLETQNNNLQAQILALQRQTVSLQ-----EQNTTLQtQNAKLQVENSTLNSQSTSLMnqNAQLLIQqssLE 1136
Cdd:COG5022 1279 EEVLPATINSLLQYINVGLFNALRTKASSLRWKsatevNYNSEEL-DDWCREFEISDVDEELEELI--QAVKVLQ---LL 1352
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1137 NENESIMKEREDL-KSLYDALIKdheklELLHERQASEYEsliskHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQlEDL 1215
Cdd:COG5022 1353 KDDLNKLDELLDAcYSLNPAEIQ-----NLKSRYDPADKE-----NNLPKEILKKIEALLIKQELQLSLEGKDETE-VHL 1421
|
650
....*....|....
gi 1390011543 1216 EKMIKTEQEKMLLE 1229
Cdd:COG5022 1422 SEIFSEEKSLISLD 1435
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
506-873 |
1.41e-09 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 62.61 E-value: 1.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 506 KVEILENEiiqekqsLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE--ARVK 583
Cdd:pfam07888 28 RAELLQNR-------LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREkhEELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 584 DIEKENKILHESIKETCGKLSKIEFEKRQMKKELEL-YKEKGERAEELENELNHLGKEnellQKKITNLKitcekletlE 662
Cdd:pfam07888 101 EKYKELSASSEELSEEKDALLAQRAAHEARIRELEEdIKTLTQRVLERETELERMKER----AKKAGAQR---------K 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 663 QENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRKGLE 742
Cdd:pfam07888 168 EEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLT---QKLTTAHRKEAENEALLEELRSLQE 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 743 LMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEM-----------ENQTLQKSLEELKISSKRL- 810
Cdd:pfam07888 245 RLNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLalregrarwaqERETLQQSAEADKDRIEKLs 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:pfam07888 325 AELQRLEERLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEK 387
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
666-1181 |
3.59e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 61.71 E-value: 3.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 666 SELERENRK-FKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELm 744
Cdd:COG4717 49 ERLEKEADElFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 745 RASFKKTERLEVSYQGLDTENQRLQKALENsnkkIQQLESELQDLEMENQTLQKSLEELKISS-----KRLEQLEKENKS 819
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLEE----LRELEEELEELEAELAELQEELEELLEQLslateEELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 820 LEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEennvkignLEKENKTLFKEINVYKESCVRLkELEKENKELVKRATI 899
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQLENELE--------AAALEERLKEARLLLLIAAALL-ALLGLGGSLLSLILT 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 900 DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIglnkerllhdeqstdDSRYKLLESKLESTLKK---SLEIKEEKI 976
Cdd:COG4717 275 IAGVLFLVLGLLALLFLLLAREKASLGKEAEELQAL---------------PALEELEEEELEELLAAlglPPDLSPEEL 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 977 AALEARLEESTNYNQQLRHELKTVKknyeaLKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNA 1056
Cdd:COG4717 340 LELLDRIEELQELLREAEELEEELQ-----LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEEL 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1057 TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTlnsqstslmnqnAQLLIQQSSLE 1136
Cdd:COG4717 415 LGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGEL------------AELLQELEELK 482
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 1390011543 1137 NENESIMKEREDLKSLYDALikdHEKLELLHERQASEYESLISKH 1181
Cdd:COG4717 483 AELRELAEEWAALKLALELL---EEAREEYREERLPPVLERASEY 524
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
359-846 |
3.81e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 61.71 E-value: 3.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 359 TKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQISR 438
Cdd:COG4717 65 KPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQ-----ELEALEA 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 439 tsELAEAPQK--SLGHEVNELTSskllkLEMENQSLTKTVEELRSTADSAAGSTSkiLKVEKENQRLNKKVEILENEIIQ 516
Cdd:COG4717 140 --ELAELPERleELEERLEELRE-----LEEELEELEAELAELQEELEELLEQLS--LATEEELQDLAEELEELQQRLAE 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 517 EKQSLQNCQNLSKDLMKEKAQLEKTIETlrenserqikilEQENEHLNQTVSSLRQRSQISA-EARVKDIEKENKILHES 595
Cdd:COG4717 211 LEEELEEAQEELEELEEELEQLENELEA------------AALEERLKEARLLLLIAAALLAlLGLGGSLLSLILTIAGV 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 596 IKETCGKLSKIEFEKRQMKKELE--------LYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSE 667
Cdd:COG4717 279 LFLVLGLLALLFLLLAREKASLGkeaeelqaLPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEE 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 668 LEREnrkfkktldsfknltFQLESLEKENSQLDEENLElrRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRAS 747
Cdd:COG4717 359 LEEE---------------LQLEELEQEIAALLAEAGV--EDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEEL 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 748 FKKT--ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEmENQTLQKSLEELKISSKRLEQLEKENKSLEQETS 825
Cdd:COG4717 422 LEALdeEELEEELEELEEELEELEEELEELREELAELEAELEQLE-EDGELAELLQELEELKAELRELAEEWAALKLALE 500
|
490 500
....*....|....*....|..
gi 1390011543 826 QLEKDKKQLEKENK-RLRQQAE 846
Cdd:COG4717 501 LLEEAREEYREERLpPVLERAS 522
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1026-1295 |
5.35e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.49 E-value: 5.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1026 EDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA-------QILALQRQTVSLQEQNT 1098
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRR 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1099 TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLI 1178
Cdd:COG1196 313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1179 SKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLED----LEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLNYTY 1254
Cdd:COG1196 393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEalaeLEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1390011543 1255 SQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQ 1295
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
770-1202 |
8.36e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 60.55 E-value: 8.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 770 KALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE--KENKRLRQQAEI 847
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 848 KDT---TLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKElvKRATIDIKTLVTLREDLVSEKLKTQQMNND 924
Cdd:COG4717 144 LPErleELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE--EELQDLAEELEELQQRLAELEEELEEAQEE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 925 LEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLES---KLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVK 1001
Cdd:COG4717 222 LEELEEELEQLENELEAAALEERLKEARLLLLIAAallALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1002 KNYEALKQRQDEERMVQSSIpvSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALktQLKQLETQNNNLQA 1081
Cdd:COG4717 302 KEAEELQALPALEELEEEEL--EELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL--QLEELEQEIAALLA 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1082 -----------QILALQRQTVSLQEQNTTLQTQ--NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKERED 1148
Cdd:COG4717 378 eagvedeeelrAALEQAEEYQELKEELEELEEQleELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAE 457
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1390011543 1149 LKSLYDALIKDHEKLELLHERQ--ASEYESLISKHGTLKSAHKNLEVEHKDLEDRY 1202
Cdd:COG4717 458 LEAELEQLEEDGELAELLQELEelKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
725-1257 |
8.62e-09 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 60.69 E-value: 8.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 725 LENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELK 804
Cdd:PRK01156 159 LEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLK 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAeikdttlEENNVKIGNLEKENKTLFKEINVYKESCVRLK 884
Cdd:PRK01156 239 SALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELE-------ERHMKIINDPVYKNRNYINDYFKYKNDIENKK 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 885 ELEKENKELVKRATIDIKTLVTLREDLvSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSR--YKLLESKLE 962
Cdd:PRK01156 312 QILSNIDAEINKYHAIIKKLSVLQKDY-NDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIeeYSKNIERMS 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 963 STLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMV------QSSIPVSGE---DDKWGRE 1033
Cdd:PRK01156 391 AFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNmemlngQSVCPVCGTtlgEEKSNHI 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1034 SQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNN-----------LQAQILALQRQTVSLQEQNT---T 1099
Cdd:PRK01156 471 INHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINksineynkiesARADLEDIKIKINELKDKHDkyeE 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1100 LQTQNAKLQVENstLNSQSTSLMNQNAQLliqqSSLENENesIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLIS 1179
Cdd:PRK01156 551 IKNRYKSLKLED--LDSKRTSWLNALAVI----SLIDIET--NRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIR 622
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1390011543 1180 KhgtlksahknLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLNYTYSQL 1257
Cdd:PRK01156 623 E----------IENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKAL 690
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
252-1348 |
1.44e-08 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 60.45 E-value: 1.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKrlqqENMNLLSDARSARMYRDELDALREK----AVRVDK--- 324
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIK----AQINDLEDVADKAISNDDPEEIEKKieniVTKIDKkkn 1187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 325 LESELSRYKERLHDIEFYKARVEELKEDNQVLLET--KTMLEDQLEGTRARSDKLHELEK-----ENLQLKAKLHDMEME 397
Cdd:TIGR01612 1188 IYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNlgKLFLEKIDEEKKKSEHMIKAMEAyiedlDEIKEKSPEIENEMG 1267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 398 RDMDRKKIEELM-------EENMTLEMAQKQSM----DESLHLGWELEQISRTSELAEAPQKSL------GHEVNE---- 456
Cdd:TIGR01612 1268 IEMDIKAEMETFnishdddKDHHIISKKHDENIsdirEKSLKIIEDFSEESDINDIKKELQKNLldaqkhNSDINLylne 1347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 457 -------LTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNK---KVE-ILENEIIQEkqSLQNCQ 525
Cdd:TIGR01612 1348 ianiyniLKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEEcksKIEsTLDDKDIDE--CIKKIK 1425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 526 NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRqrsqISAEARVKDIEKENKILHESIKETCGKLSK 605
Cdd:TIGR01612 1426 ELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILK----IKKDNATNDHDFNINELKEHIDKSKGCKDE 1501
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 606 IEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKtldsFKNL 685
Cdd:TIGR01612 1502 ADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKE----IKKE 1577
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 686 TFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTErLEVSYQGLDTEn 765
Cdd:TIGR01612 1578 KFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKINDCLKETESIEKKISSFSIDSQDTE-LKENGDNLNSL- 1655
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 766 QRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKiSSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQA 845
Cdd:TIGR01612 1656 QEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHK-KNYEIGIIEKIKEIAIANKEEIESIKELIEPTIENLISSF 1734
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 846 EIKD-------TTLEENNVKIGNLEKENKTLFKEINVYKESCVR-------------------LKELEKENKELVKRATI 899
Cdd:TIGR01612 1735 NTNDlegidpnEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSKepitydeikntrinaqnefLKIIEIEKKSKSYLDDI 1814
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 900 DIKTLvtlreDLVSEKLKtQQMNNDLEKLTHELEKI---------GLNKERLLHDEQSTDDSRYKLLESKLESTLKK--S 968
Cdd:TIGR01612 1815 EAKEF-----DRIINHFK-KKLDHVNDKFTKEYSKInegfddiskSIENVKNSTDENLLFDILNKTKDAYAGIIGKKyyS 1888
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 969 LEIKEEKIAALEARLEESTNYNQQLRHELKTVKK-NYEALKQRQDEERMVQSSIPvsgeddkwgrESQEATRELLKVKDR 1047
Cdd:TIGR01612 1889 YKDEAEKIFINISKLANSINIQIQNNSGIDLFDNiNIAILSSLDSEKEDTLKFIP----------SPEKEPEIYTKIRDS 1958
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1048 LievernNATLQAEKQALKTQLKQLETQN-NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA 1126
Cdd:TIGR01612 1959 Y------DTLLDIFKKSQDLHKKEQDTLNiIFENQQLYEKIQASNELKDTLSDLKYKKEKILNDVKLLLHKFDELNKLSC 2032
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1127 QLLIQQSSLENENESIMKEREDLKSlydaliKDHEKLELLHERQASE--YESLISKHGTLKSAHKNLEVEHKDLEDRYNQ 1204
Cdd:TIGR01612 2033 DSQNYDTILELSKQDKIKEKIDNYE------KEKEKFGIDFDVKAMEekFDNDIKDIEKFENNYKHSEKDNHDFSEEKDN 2106
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1205 LLKQKGQLEDLEKMIKTEQEKM---LLESKNHEVVASEYKKLCgendrLNYTYSQLLKeteilqmdhkNLKS-VLNNSKL 1280
Cdd:TIGR01612 2107 IIQSKKKLKELTEAFNTEIKIIedkIIEKNDLIDKLIEMRKEC-----LLFSYATLVE----------TLKSkVINHSEF 2171
|
1130 1140 1150 1160 1170 1180
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1390011543 1281 EQTrlEAEFSKlkEQYQQLDITSTKLNNQCELLsQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMES 1348
Cdd:TIGR01612 2172 ITS--AAKFSK--DFFEFIEDISDSLNDDIDAL-QIKYNLNQTKKHMISILADATKDHNNLIEKEKEA 2234
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
883-1347 |
1.65e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.78 E-value: 1.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 883 LKELEKENKELVK----RATIDIKTLVTLREDLVSEKLKT---QQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYK 955
Cdd:COG4717 48 LERLEKEADELFKpqgrKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 956 LLESKLESTLKKSLEIKEEKIAALEARLEEStnynQQLRHELKTVKKNYEALKQRQDEERMVQSsipvsgedDKWGRESQ 1035
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELLEQLS--------LATEEELQ 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1036 EATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQiLALQRQTVSLQEQNTTLQTQNAKLQVENSTLN 1115
Cdd:COG4717 196 DLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE-ERLKEARLLLLIAAALLALLGLGGSLLSLILT 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1116 SQ-----STSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDH-EKLELLHERQASEYESLISKHGTLKSAHK 1189
Cdd:COG4717 275 IAgvlflVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELlAALGLPPDLSPEELLELLDRIEELQELLR 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1190 NL-----EVEHKDLEDRYNQLLKQKGQ--LEDLEKMIKTEQEKMLLESKNHEVvaseykklcgeNDRLNYTYSQLLKETE 1262
Cdd:COG4717 355 EAeeleeELQLEELEQEIAALLAEAGVedEEELRAALEQAEEYQELKEELEEL-----------EEQLEELLGELEELLE 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1263 ILqmDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEL--LSQLKGNLEEENRHLLDQIQTLMLQnRT 1340
Cdd:COG4717 424 AL--DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELaeLLQELEELKAELRELAEEWAALKLA-LE 500
|
....*..
gi 1390011543 1341 LLEQNME 1347
Cdd:COG4717 501 LLEEARE 507
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
594-837 |
1.86e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.62 E-value: 1.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 594 ESIKETCGKLSKIEFEKRQMKKELELYKEKgerAEELENELNHLGKENELLQKKITNLKitcEKLETLEQENSELERENR 673
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKE---EKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 674 KFKKTLDSFKN-LTFQLESLEKENSQldeENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKglelmrasfkKTE 752
Cdd:COG4942 94 ELRAELEAQKEeLAELLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRA----------DLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 753 RLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKK 832
Cdd:COG4942 161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELA---AELAELQQEAEELEALIARLEAEAA 237
|
....*
gi 1390011543 833 QLEKE 837
Cdd:COG4942 238 AAAER 242
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
824-1180 |
3.17e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.93 E-value: 3.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL--EKENKTLFKEINVYKEScVRLKELEKENKELVK-RATID 900
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLrrEREKAERYQALLKEKRE-YEGYELLKEKEALERqKEAIE 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 901 iKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTlkksleikEEKIAALE 980
Cdd:TIGR02169 244 -RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--------ERSIAEKE 314
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 981 ARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERmvqssipvsGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQA 1060
Cdd:TIGR02169 315 RELEDAEERLAKLEAEIDKLLAEIEELEREIEEER---------KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1061 EKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE 1140
Cdd:TIGR02169 386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 1390011543 1141 SIMKEREDLKSLYDALIKDHEKLE-----LLHERQASEYESLISK 1180
Cdd:TIGR02169 466 KYEQELYDLKEEYDRVEKELSKLQrelaeAEAQARASEERVRGGR 510
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
508-894 |
4.29e-08 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 57.77 E-value: 4.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 508 EILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK---ILEQE---NEHLNQTVSSLRQRSQiSAEAR 581
Cdd:pfam19220 6 ELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLEleaLLAQEraaYGKLRRELAGLTRRLS-AAEGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 582 VKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELE-----LYKEKgERAEELENELNHLGKENELLQKKITNLKitcE 656
Cdd:pfam19220 85 LEELVARLAKLEAALREAEAAKEELRIELRDKTAQAEalerqLAAET-EQNRALEEENKALREEAQAAEKALQRAE---G 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 657 KLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESlKCASMR------MAQLQLENKEL 730
Cdd:pfam19220 161 ELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEG-QLAAEQaereraEAQLEEAVEAH 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 731 ESEKEQLRKGLELMRASFKKTERLevsyqgldtenqrlqkalensnkkIQQLESELQDLEMENQTLQKSLEELKIS---- 806
Cdd:pfam19220 240 RAERASLRMKLEALTARAAATEQL------------------------LAEARNQLRDRDEAIRAAERRLKEASIErdtl 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 807 SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEScvrlkeL 886
Cdd:pfam19220 296 ERRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAA------L 369
|
....*...
gi 1390011543 887 EKENKELV 894
Cdd:pfam19220 370 EQANRRLK 377
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
726-934 |
4.56e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 57.47 E-value: 4.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 726 ENKELESEKEQLRKGLELMRASFKKTERLEVSYQG----LDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLE 801
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKqlaaLERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 802 ELKIS-SKRLEQLEKENKS------LEQET-SQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEI 873
Cdd:COG4942 101 AQKEElAELLRALYRLGRQpplallLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1390011543 874 NVYKESCVRLKELEKENKELVKRATidiKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEK 934
Cdd:COG4942 181 AELEEERAALEALKAERQKLLARLE---KELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
796-1158 |
6.79e-08 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 58.00 E-value: 6.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 796 LQKSLEELKissKRlEQLEKENKSLEQ---ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKE 872
Cdd:PRK11281 41 VQAQLDALN---KQ-KLLEAEDKLVQQdleQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 873 INvykeSCVRLKELEKE-NKELVKRATIDiKTLVTLREDLVS-----EKLKTQQMNND--LEKLTHELEKIGLNKERLLH 944
Cdd:PRK11281 117 TL----STLSLRQLESRlAQTLDQLQNAQ-NDLAEYNSQLVSlqtqpERAQAALYANSqrLQQIRNLLKGGKVGGKALRP 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 945 DEQSTDDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKknyEAL--KQRQDEERMVQSSIp 1022
Cdd:PRK11281 192 SQRVLLQAEQALLNAQND-LQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQ---EAInsKRLTLSEKTVQEAQ- 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1023 vSGEDDKWGRESQEATREL---LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAL------------Q 1087
Cdd:PRK11281 267 -SQDEAARIQANPLVAQELeinLQLSQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLkgslllsrilyqQ 345
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1390011543 1088 RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA---QLLIQQSSLENENE-----SIMKEREDlksLYDALIK 1158
Cdd:PRK11281 346 QQALPSADLIEGLADRIADLRLEQFEINQQRDALFQPDAyidKLEAGHKSEVTDEVrdallQLLDERRE---LLDQLNK 421
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
559-914 |
8.09e-08 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 57.44 E-value: 8.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 559 ENEHLNQTVSSLRQRSQISAEARVKDIEK-ENKILHESIKETCGKLSK----IEFEK-RQ--MKKELELYKEKGERAEEL 630
Cdd:pfam17380 267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKmEQERLRQEKEEKAREVERrrklEEAEKaRQaeMDRQAAIYAEQERMAMER 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 631 ENELNHLGKEN---ELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Cdd:pfam17380 347 ERELERIRQEErkrELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIR 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 708 RSVESLKcasmrmaqlQLENKELESEKEQlrkglELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESElq 787
Cdd:pfam17380 427 AEQEEAR---------QREVRRLEEERAR-----EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAE-- 490
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 788 dlEMENQTLQKSLEElkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK--E 865
Cdd:pfam17380 491 --EQRRKILEKELEE-----RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKatE 563
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1390011543 866 NKTLFKEINVYKESCVRLKELEKENKELvkRATIDIKTLVTLREDLVSE 914
Cdd:pfam17380 564 ERSRLEAMEREREMMRQIVESEKARAEY--EATTPITTIKPIYRPRISE 610
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
261-868 |
8.23e-08 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 57.78 E-value: 8.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 261 RRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENmnllsdarsarmyrDELDALREKAVRVDKLESELSRYKErlhdie 340
Cdd:COG5022 857 AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDV--------------KSISSLKLVNLELESEIIELKKSLS------ 916
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 341 fykarvEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN-----LQLKAKLHDMEMERDMDRKKIEELMEENMTL 415
Cdd:COG5022 917 ------SDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPelnklHEVESKLKETSEEYEDLLKKSTILVREGNKA 990
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 416 EMAQKQSMDESLHLGWELEQISRTSELAeapqKSLGHEVNELTS-SKLLKLEMENQSLTKTVEELRSTADSAAGSTS--- 491
Cdd:COG5022 991 NSELKNFKKELAELSKQYGALQESTKQL----KELPVEVAELQSaSKIISSESTELSILKPLQKLKGLLLLENNQLQary 1066
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 492 KILKVEKENQRLNKK-------VEILENEiIQEKQSLQNCQNLSKDLMKE---KAQLEKTIETLR--ENSERQIKILEQE 559
Cdd:COG5022 1067 KALKLRRENSLLDDKqlyqlesTENLLKT-INVKDLEVTNRNLVKPANVLqfiVAQMIKLNLLQEisKFLSQLVNTLEPV 1145
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 560 NEHLNQT---------VSSLRQRSQISAEARVKDIEKenkiLHESIKETCGKLSKIefekrqmkkELELYKEKGERAEEL 630
Cdd:COG5022 1146 FQKLSVLqleldglfwEANLEALPSPPPFAALSEKRL----YQSALYDEKSKLSSS---------EVNDLKNELIALFSK 1212
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 631 ENELNHLGKENELLQKKITNLKITCEKL-ETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKE--------NSQLDE 701
Cdd:COG5022 1213 IFSGWPRGDKLKKLISEGWVPTEYSTSLkGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEeevlpatiNSLLQY 1292
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 702 ENLELRRSVeSLKCASMRMAQLQ--------LENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTenqRLQKALE 773
Cdd:COG5022 1293 INVGLFNAL-RTKASSLRWKSATevnynseeLDDWCREFEISDVDEELEELIQAVKVLQLLKDDLNKLDE---LLDACYS 1368
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 774 NSNKKIQQLESELQDLEMENQTLQKSLEELKISS-KRLEQLEKENK-SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT 851
Cdd:COG5022 1369 LNPAEIQNLKSRYDPADKENNLPKEILKKIEALLiKQELQLSLEGKdETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSL 1448
|
650
....*....|....*..
gi 1390011543 852 leENNVKIGNLEKENKT 868
Cdd:COG5022 1449 --SALLTKEKIALLDRK 1463
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
743-897 |
8.81e-08 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 57.17 E-value: 8.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 743 LMRASFKKTERLEVSYQGLDTENQRLQKALEnsnKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQ 822
Cdd:COG2433 382 LEELIEKELPEEEPEAEREKEHEERELTEEE---EEIRRLEEQVERLEAEVEELEAELEEKD---ERIERLERELSEARS 455
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1390011543 823 ET-SQLEKDKK--QLEKENKRLRQQAEIKDTTLEENNVKignLEKENKTLFKEInvyKESCVRLKELEKENKELVKRA 897
Cdd:COG2433 456 EErREIRKDREisRLDREIERLERELEEERERIEELKRK---LERLKELWKLEH---SGELVPVKVVEKFTKEAIRRL 527
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
501-1418 |
8.90e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 57.75 E-value: 8.90e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 501 QRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQL--EKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQiSA 578
Cdd:TIGR00606 196 QTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLesSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIK-AL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 579 EARVKDIEKENKILHEsiketcgKLSKIEFEKRQMKKELELY-----KEKGERAEELENELNHLGKENELLQKKITNLKI 653
Cdd:TIGR00606 275 KSRKKQMEKDNSELEL-------KMEKVFQGTDEQLNDLYHNhqrtvREKERELVDCQRELEKLNKERRLLNQEKTELLV 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 654 TCEKLETLEQENSE------LERENRKFKKTLDSFKNLTFqLESLEKENSQLDEENLELRRSVESLKCASM----RMAQL 723
Cdd:TIGR00606 348 EQGRLQLQADRHQEhirardSLIQSLATRLELDGFERGPF-SERQIKNFHTLVIERQEDEAKTAAQLCADLqskeRLKQE 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 724 QLEnkELESEKEQLRKGLELmrasfkKTERLEvsyqgldtenqRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEEL 803
Cdd:TIGR00606 427 QAD--EIRDEKKGLGRTIEL------KKEILE-----------KKQEELKFVIKELQQLEGSSDRILELDQELRKAEREL 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 804 KISSKR--LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL---EENNVKIGNLEKENKTLFKEINVYKE 878
Cdd:TIGR00606 488 SKAEKNslTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltKDKMDKDEQIRKIKSRHSDELTSLLG 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 879 SCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIglnkERLLHDEQSTDDsryklLE 958
Cdd:TIGR00606 568 YFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY----EDKLFDVCGSQD-----EE 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 959 SKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRHElktvkknyealkqrqdeermVQSSIPVSGEDDKWGRESQEAT 1038
Cdd:TIGR00606 639 SDLER-LKEEIEKSSKQRAMLAGATAVYSQFITQLTDE--------------------NQSCCPVCQRVFQTEAELQEFI 697
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1039 RELlKVKDRLIEVErnnatLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQS 1118
Cdd:TIGR00606 698 SDL-QSKLRLAPDK-----LKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQE 771
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1119 TSLMNQNAQLliqqsslenenesimKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDl 1198
Cdd:TIGR00606 772 TLLGTIMPEE---------------ESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQ- 835
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1199 edryNQLLKQKGQLEDLEKMIKTEQEKML-LESKNHEVvaSEYKKLCGENDRlnyTYSQLLKETEILQMDHKNLKSVLNN 1277
Cdd:TIGR00606 836 ----HELDTVVSKIELNRKLIQDQQEQIQhLKSKTNEL--KSEKLQIGTNLQ---RRQQFEEQLVELSTEVQSLIREIKD 906
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1278 SKLEQTRLEaefsKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENrhlLDQIQTLMlqnRTLLEQNMESKDLFHVEQR 1357
Cdd:TIGR00606 907 AKEQDSPLE----TFLEKDQQEKEELISSKETSNKKAQDKVNDIKEK---VKNIHGYM---KDIENKIQDGKDDYLKQKE 976
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 1358 QYIDK----LNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSL 1418
Cdd:TIGR00606 977 TELNTvnaqLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHL 1041
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
512-855 |
9.50e-08 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 57.01 E-value: 9.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 512 NEIIQEKQSL-QNCQNLSKD---LMKEKAQLEKTIETLRENSER--------------------QIKILEQENEHLNQTV 567
Cdd:pfam05622 3 SEAQEEKDELaQRCHELDQQvslLQEEKNSLQQENKKLQERLDQlesgddsgtpggkkylllqkQLEQLQEENFRLETAR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 568 SSLRQRSQIsaearvkdIEKENKILHESIKEtcgkLSKIEFEKRQMKKELELYKEKGERAEELE----------NELNHL 637
Cdd:pfam05622 83 DDYRIKCEE--------LEKEVLELQHRNEE----LTSLAEEAQALKDEMDILRESSDKVKKLEatvetykkklEDLGDL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 638 GKENELLQKKITN-LKITCE-------------KLETLEQENSELER----ENRKFKKTLDSFKNLTFQLESLEKENSQL 699
Cdd:pfam05622 151 RRQVKLLEERNAEyMQRTLQleeelkkanalrgQLETYKRQVQELHGklseESKKADKLEFEYKKLEEKLEALQKEKERL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 700 DEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRK-GLELMRASFKKT-ERLEVSYQGLD-----TENQR---LQ 769
Cdd:pfam05622 231 IIERDTLRETNEELRCAQLQQAELSQADALLSPSSDPGDNlAAEIMPAEIREKlIRLQHENKMLRlgqegSYRERlteLQ 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 770 KALENSNKKIQQLESEL-----QDLEMENQT--LQKSLEEL----KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:pfam05622 311 QLLEDANRRKNELETQNrlanqRILELQQQVeeLQKALQEQgskaEDSSLLKQKLEEHLEKLHEAQSELQKKKEQIEELE 390
|
410
....*....|....*..
gi 1390011543 839 KRLRQQAEIKDTTLEEN 855
Cdd:pfam05622 391 PKQDSNLAQKIDELQEA 407
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
991-1208 |
1.17e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.31 E-value: 1.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 991 QQLRHELKTVKKNYEALKQRQDEERMVQSSIpvSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKtqlK 1070
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKAL--LKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR---A 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1071 QLETQNNNLQAQILALQRQtvSLQEQNTTLQTQNAKLQVENST--LNSQSTSLMNQNAQLLIQQSSLENENESIMKERED 1148
Cdd:COG4942 98 ELEAQKEELAELLRALYRL--GRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1149 LKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQ 1208
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
746-988 |
2.31e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.16 E-value: 2.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 746 ASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissKRLEQLEKENKSLEQETS 825
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 826 QLEKDKKQLEKE-NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLfkeinvykescVRLKELEKENKELVKRATIDIKTL 904
Cdd:COG4942 94 ELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRL-----------QYLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLhdeqSTDDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLE 984
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLL----ARLEKELAELAAELA-ELQQEAEELEALIARLEAEAA 237
|
....
gi 1390011543 985 ESTN 988
Cdd:COG4942 238 AAAE 241
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
764-1014 |
3.26e-07 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 55.32 E-value: 3.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 764 ENQRLQKALENS---NKKIQQLESELQDLEMENQTLQ----KSLEEL-KISSKRLEQLEKENKSLEQETSQLEKDKKQLE 835
Cdd:PRK05771 41 SNERLRKLRSLLtklSEALDKLRSYLPKLNPLREEKKkvsvKSLEELiKDVEEELEKIEKEIKELEEEISELENEIKELE 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 836 KENKRLRqqaeikdttleennvKIGNLEKENKTLFKEINVYkescVRLKELEKENKELVKrATIDIKTLVTLRED----- 910
Cdd:PRK05771 121 QEIERLE---------------PWGNFDLDLSLLLGFKYVS----VFVGTVPEDKLEELK-LESDVENVEYISTDkgyvy 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 911 --LVSEKlktqqmnNDLEKLTHELEKIGLnkerllhdeqstddSRYKLLESKlesTLKKSLEIKEEKIAALEARLEEstn 988
Cdd:PRK05771 181 vvVVVLK-------ELSDEVEEELKKLGF--------------ERLELEEEG---TPSELIREIKEELEEIEKERES--- 233
|
250 260
....*....|....*....|....*.
gi 1390011543 989 ynqqLRHELKTVKKNYEALKQRQDEE 1014
Cdd:PRK05771 234 ----LLEELKELAKKYLEELLALYEY 255
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
917-1148 |
3.51e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.77 E-value: 3.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRyKLLESKLeSTLKKSLEIKEEKIAALEARLEESTNYNQQLRHE 996
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL-AALERRI-AALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 997 LKTVKKNY-EALKQRQDEERMVQSSIPVSGEDdkwgreSQEATRellkvkdRLIEVERNNATLQAEKQALKTQLKQLETQ 1075
Cdd:COG4942 99 LEAQKEELaELLRALYRLGRQPPLALLLSPED------FLDAVR-------RLQYLKYLAPARREQAEELRADLAELAAL 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 1076 NNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKERED 1148
Cdd:COG4942 166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
183-697 |
4.02e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 55.36 E-value: 4.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 183 QEDIEPLLKNMVSHLRRLIDERDEHSETIVELSEERDGVHFLPHASSSAQSPCGSPGMKRTESRQHLSVELAdAKAKIRR 262
Cdd:TIGR00618 385 QQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKL-EKIHLQE 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 263 LRQELEEKTEQLLD----CKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSRYKERLHD 338
Cdd:TIGR00618 464 SAQSLKEREQQLQTkeqiHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETS 543
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 339 IEfykarveelKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENlQLKAKLHDMEMERDMDRKKIEELMEENMTLEMA 418
Cdd:TIGR00618 544 EE---------DVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDN-RSKEDIPNLQNITVRLQDLTEKLSEAEDMLACE 613
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 419 QKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSskLLKLEMENQSLTKTVEELRSTAdsaagstskilkvek 498
Cdd:TIGR00618 614 QHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLT--LTQERVREHALSIRVLPKELLA--------------- 676
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 499 ENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA 578
Cdd:TIGR00618 677 SRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVL 756
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 579 EARVKDieKENKILHESIKETCG-KLSKIEFEKRQMKKELE-LYKEKGERAEELENELNHLGKENELLQKKI-------- 648
Cdd:TIGR00618 757 KARTEA--HFNNNEEVTAALQTGaELSHLAAEIQFFNRLREeDTHLLKTLEAEIGQEIPSDEDILNLQCETLvqeeeqfl 834
|
490 500 510 520
....*....|....*....|....*....|....*....|....*....
gi 1390011543 649 TNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENS 697
Cdd:TIGR00618 835 SRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQ 883
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
611-1183 |
4.18e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.31 E-value: 4.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 611 RQMKKELELYKEKGERAEELENELNHLGKENELlqkkitnlkitCEKLETLEQENSELEREnrkfKKTLDSFKNLTfQLE 690
Cdd:COG4913 228 DALVEHFDDLERAHEALEDAREQIELLEPIREL-----------AERYAAARERLAELEYL----RAALRLWFAQR-RLE 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 691 SLEKEnsqLDEENLELRRSVEslkcasmRMAQLQLENKELESEKEQLRKglELMRASFKKTERLEvsyqgldTENQRLQK 770
Cdd:COG4913 292 LLEAE---LEELRAELARLEA-------ELERLEARLDALREELDELEA--QIRGNGGDRLEQLE-------REIERLER 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 771 ALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSK-RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQqaEIKD 849
Cdd:COG4913 353 ELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAaLLEALEEELEALEEALAEAEAALRDLRRELRELEA--EIAS 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 850 ttLEENNVKI-GNLEKENKTLFKEINVYKESC--------VRLKEL-------------------EKENKELVKRATIDI 901
Cdd:COG4913 431 --LERRKSNIpARLLALRDALAEALGLDEAELpfvgelieVRPEEErwrgaiervlggfaltllvPPEHYAAALRWVNRL 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 902 KT---LVTLREDLVSEKLKTQQMNND--LEKLT-----------HELEKI-----------------GLNKERLLHDEQS 948
Cdd:COG4913 509 HLrgrLVYERVRTGLPDPERPRLDPDslAGKLDfkphpfrawleAELGRRfdyvcvdspeelrrhprAITRAGQVKGNGT 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 949 T---DDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDeermvqssipVSG 1025
Cdd:COG4913 589 RhekDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE----------YSW 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1026 EDDKWgresQEATRELLKVKDRLIEVERNNATLQAekqaLKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA 1105
Cdd:COG4913 659 DEIDV----ASAEREIAELEAELERLDASSDDLAA----LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELD 730
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1390011543 1106 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKE-REDLKSLYDALIKDHEKLELLHERQASEYESLISKHGT 1183
Cdd:COG4913 731 ELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENlEERIDALRARLNRAEEELERAMRAFNREWPAETADLDA 809
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
658-1262 |
4.41e-07 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 55.21 E-value: 4.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 658 LETLEQENSELERE----NRKFKKTLDSFKnlTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESE 733
Cdd:pfam10174 5 LRDLQRENELLRREldikESKLGSSMNSIK--TFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 734 KEQLRKGLELMRASFKKTERlevsyqglDTENQRLQKALENSNkkIQQLESELQDLEMENQTLQKSLE--ELKISSKRlE 811
Cdd:pfam10174 83 LRAQRDLNQLLQQDFTTSPV--------DGEDKFSTPELTEEN--FRRLQSEHERQAKELFLLRKTLEemELRIETQK-Q 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 812 QLEKENKSLEQ--ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLfkeinvyKESCVRLKELEKE 889
Cdd:pfam10174 152 TLGARDESIKKllEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHL-------REELHRRNQLQPD 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 890 NKElvkratidIKTLVTLREDLVSEKLKTQQMNNDLEkltheLEKIGLNKERLLHDEQSTDD--------SRYKLLESKL 961
Cdd:pfam10174 225 PAK--------TKALQTVIEMKDTKISSLERNIRDLE-----DEVQMLKTNGLLHTEDREEEikqmevykSHSKFMKNKI 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 962 EsTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDeerMVQSsipvsgEDDKWGRESQEATREL 1041
Cdd:pfam10174 292 D-QLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAA---ILQT------EVDALRLRLEEKESFL 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1042 LKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSL 1121
Cdd:pfam10174 362 NKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTL 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1122 MNQNA------QLLIQQSSLEN-----ENESIMKEREDLKSLYDALIKDHEKLEL----LHERQASEYESLISKHGTLKS 1186
Cdd:pfam10174 442 EEALSekeriiERLKEQREREDrerleELESLKKENKDLKEKVSALQPELTEKESslidLKEHASSLASSGLKKDSKLKS 521
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1390011543 1187 AHKNLEVEHKDLEDRYNQLLKQKgQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLnytySQLLKETE 1262
Cdd:pfam10174 522 LEIAVEQKKEECSKLENQLKKAH-NAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERL----LGILREVE 592
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
247-1038 |
5.35e-07 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 54.84 E-value: 5.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 247 QHLSVELadaKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSA-RMYRDELDALREKAVRVDKL 325
Cdd:pfam12128 261 SHLHFGY---KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvAKDRSELEALEDQHGAFLDA 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 326 ESElsRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDklhelekenLQLKAKLHDMEMERDMDRkki 405
Cdd:pfam12128 338 DIE--TAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---------EQNNRDIAGIKDKLAKIR--- 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 406 eelmeenmtlemaqkqsmdeslhlgwelEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADS 485
Cdd:pfam12128 404 ----------------------------EARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQ 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 486 AAGSTSKILKVEKENQRLNKkveileneiIQEKQSLQNCQnlskdlmKEKAQLEktietlrensERQIKIL-EQENEHLN 564
Cdd:pfam12128 456 ATATPELLLQLENFDERIER---------AREEQEAANAE-------VERLQSE----------LRQARKRrDQASEALR 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 565 QTVSSLRQRSQISAEARVKDIEKENKILH------ESIKETCGKLSKIEFEKRQmkkelelykekgeraeELENELNHLG 638
Cdd:pfam12128 510 QASRRLEERQSALDELELQLFPQAGTLLHflrkeaPDWEQSIGKVISPELLHRT----------------DLDPEVWDGS 573
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 639 KENELlqkKITNLKITCEKLETLE--QENSELERENRKFKKTLDSFKNLTFQLES-LEKENSQLDEENLELRRSVESLKC 715
Cdd:pfam12128 574 VGGEL---NLYGVKLDLKRIDVPEwaASEEELRERLDKAEEALQSAREKQAAAEEqLVQANGELEKASREETFARTALKN 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 716 ASMRMAQLqleNKELESEKEQLRKGLElmRASFKKTERLevsyQGLDTEnqrlQKALENsnkKIQQLESELQDLEMENQT 795
Cdd:pfam12128 651 ARLDLRRL---FDEKQSEKDKKNKALA--ERKDSANERL----NSLEAQ----LKQLDK---KHQAWLEEQKEQKREART 714
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 796 lQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRlrqqaEIKDTTLEENNvkIGNLEKENKTLFKeinv 875
Cdd:pfam12128 715 -EKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKR-----DLASLGVDPDV--IAKLKREIRTLER---- 782
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 876 ykescvRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE-KLTHELEKIGLNKERLLHDEQSTDDSRY 954
Cdd:pfam12128 783 ------KIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQqQLARLIADTKLRRAKLEMERKASEKQQV 856
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 955 KLLE--SKLESTLKKSLEIKEEKIAA-LEARLEESTNYNQQLRHELKTVKknyEALKQRQDEERMVQSSIPVSGEDDKWG 1031
Cdd:pfam12128 857 RLSEnlRGLRCEMSKLATLKEDANSEqAQGSIGERLAQLEDLKLKRDYLS---ESVKKYVEHFKNVIADHSGSGLAETWE 933
|
....*..
gi 1390011543 1032 RESQEAT 1038
Cdd:pfam12128 934 SLREEDH 940
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
482-1301 |
6.60e-07 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 54.84 E-value: 6.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 482 TADSAAGSTSKILKVEKenqRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEqene 561
Cdd:PTZ00440 430 IADYALYSNLEIIEIKK---KYDEKINELKKSINQLKTLISIMKSFYDLIISEKDSMDSKEKKESSDSNYQEKVDE---- 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 562 hLNQTVSSLRQRSQISAEaRVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKEN 641
Cdd:PTZ00440 503 -LLQIINSIKEKNNIVNN-NFKNIEDYYITIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENV 580
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 642 ELLQKKITNLKITCEKLETLEQENSELERENRKFKKtldsfknltfqleslEKENSQLDEENLELRRSVESLKCASMRMA 721
Cdd:PTZ00440 581 DHIKDIISLNDEIDNIIQQIEELINEALFNKEKFIN---------------EKNDLQEKVKYILNKFYKGDLQELLDELS 645
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 722 QLQLENKELESEKEQLRKGLELMRASFKKTERLEvsyqgldtenqrlQKALENSNKKIQQLESELQDL-EMENQTLQKSL 800
Cdd:PTZ00440 646 HFLDDHKYLYHEAKSKEDLQTLLNTSKNEYEKLE-------------FMKSDNIDNIIKNLKKELQNLlSLKENIIKKQL 712
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 801 EELKIS-SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIgnleKENKTLFKEINVYKES 879
Cdd:PTZ00440 713 NNIEQDiSNSLNQYTIKYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDL----PDGKNTYEEFLQYKDT 788
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 880 CVRLKELEKENKELVKRATIDIKTLVTLREDLVsEKLKTQQMNNDlEKLTHELEKIGLNKERLLHDEqstDDSRYKLLES 959
Cdd:PTZ00440 789 ILNKENKISNDINILKENKKNNQDLLNSYNILI-QKLEAHTEKND-EELKQLLQKFPTEDENLNLKE---LEKEFNENNQ 863
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 960 KLESTLKKSLEI--KEEKIAALEARLEESTNYNQQLRHelktVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESqEA 1037
Cdd:PTZ00440 864 IVDNIIKDIENMnkNINIIKTLNIAINRSNSNKQLVEH----LLNNKIDLKNKLEQHMKIINTDNIIQKNEKLNLLN-NL 938
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1038 TRELLKVKDRLIEVERNNATLQAEKQaLKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENstlnsq 1117
Cdd:PTZ00440 939 NKEKEKIEKQLSDTKINNLKMQIEKT-LEYYDKSKENINGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILN------ 1011
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1118 stslmnqnaqlliqqsslENENESIMKEREDLKSLYDALIKdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKD 1197
Cdd:PTZ00440 1012 ------------------KKIDDLIKKQHDDIIELIDKLIK--EKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYK 1071
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1198 LEDRYNQLLKQKGQLEDLEKMIKTEQEKML-LESKNHEVVASeykkLCGENDRLNYTYSQLLKETEILQMDHKNLKSVLN 1276
Cdd:PTZ00440 1072 NPKIKEEIKLLEEKVEALLKKIDENKNKLIeIKNKSHEHVVN----ADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKELE 1147
|
810 820
....*....|....*....|....*
gi 1390011543 1277 NSKLEQTRLEaEFSKLKEQYQQLDI 1301
Cdd:PTZ00440 1148 NMNLEDITLN-EVNEIEIEYERILI 1171
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
547-867 |
6.65e-07 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 54.52 E-value: 6.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 547 ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHEsiKETC-GKLSKIEFEKRQMKKELELYKEKGE 625
Cdd:PLN02939 117 TNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQARLQALEDLEKILTE--KEALqGKINILEMRLSETDARIKLAAQEKI 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 626 RAEELENELNHLgkENELLQKKITNLKITC---EKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDee 702
Cdd:PLN02939 195 HVEILEEQLEKL--RNELLIRGATEGLCVHslsKELDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERSLLD-- 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 703 nlelrrsveslkcASMRmaqlQLENKELESEKEQLRKGLELMRASFKKTERLEVsyqgldtenqRLQKALENSNKKIQQL 782
Cdd:PLN02939 271 -------------ASLR----ELESKFIVAQEDVSKLSPLQYDCWWEKVENLQD----------LLDRATNQVEKAALVL 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 783 ESElQDLEMENQTLQKSLEE---LKISSKRLEQLEKENKSLEQetsqlekdkkQLEKENKRLRQQAEIKDTTLEENNVKI 859
Cdd:PLN02939 324 DQN-QDLRDKVDKLEASLKEanvSKFSSYKVELLQQKLKLLEE----------RLQASDHEIHSYIQLYQESIKEFQDTL 392
|
....*...
gi 1390011543 860 GNLEKENK 867
Cdd:PLN02939 393 SKLKEESK 400
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
882-1374 |
7.64e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 54.30 E-value: 7.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLK-TQQMNNDLEKLTHELEKIGLNKERLlhdeqstDDSRYKLLESK 960
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLReINEISSELPELREELEKLEKEVKEL-------EELKEEIEELE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 961 LE-STLKKSLEIKEEKIAALEARLEESTNYNQQLRH------ELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRE 1033
Cdd:PRK03918 245 KElESLEGSKRKLEEKIRELEERIEELKKEIEELEEkvkelkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEIN 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1034 S-QEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETqnnnlqaqILALQRQTVSLQEQNTTLQTQNAKLQVENs 1112
Cdd:PRK03918 325 GiEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEE--------AKAKKEELERLKKRLTGLTPEKLEKELEE- 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1113 tLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKS------LYDALIKDHEKLELLherqaSEYESLIskhgtlks 1186
Cdd:PRK03918 396 -LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpVCGRELTEEHRKELL-----EEYTAEL-------- 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1187 ahKNLEVEHKDLEDRYNQLLKQkgqLEDLEKMIKTEQEKMLLESknhevVASEYKKLCGENDRLNytysqlLKETEILQM 1266
Cdd:PRK03918 462 --KRIEKELKEIEEKERKLRKE---LRELEKVLKKESELIKLKE-----LAEQLKELEEKLKKYN------LEELEKKAE 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1267 DHKNLKSVLNNSKLEQTRLEAEFSKLKEqyqqlditstkLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNM 1346
Cdd:PRK03918 526 EYEKLKEKLIKLKGEIKSLKKELEKLEE-----------LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL 594
|
490 500
....*....|....*....|....*...
gi 1390011543 1347 ESKDLFHVEQRQYIDKLNELRRQKEKLE 1374
Cdd:PRK03918 595 KELEPFYNEYLELKDAEKELEREEKELK 622
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
820-1382 |
1.11e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 53.96 E-value: 1.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 820 LEQETSQLEKDKKQLEKENKRLRQ---QAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKE---NKEL 893
Cdd:pfam05483 101 LKQKENKLQENRKIIEAQRKAIQElqfENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKyeyEREE 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 894 VKRATIDIKTLVTlREDLVSEKLKTQQMNNDLE---KLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLEstlkksle 970
Cdd:pfam05483 181 TRQVYMDLNNNIE-KMILAFEELRVQAENARLEmhfKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITE-------- 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 971 iKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKwgrESQEATRELLKVKDRLI- 1049
Cdd:pfam05483 252 -KENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSM---STQKALEEDLQIATKTIc 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1050 --------EVERNN--------------ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQntTLQTQNAKL 1107
Cdd:pfam05483 328 qlteekeaQMEELNkakaahsfvvtefeATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEM--TKFKNNKEV 405
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1108 QVEnstlnsQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSA 1187
Cdd:pfam05483 406 ELE------ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTE 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1188 HKNLEVEHKDLEDRYNQLLKQKgqledleKMIKTEQEKMLLESKNHEVVASEYKKlcgendrlnyTYSQLLKETEILQMD 1267
Cdd:pfam05483 480 LEKEKLKNIELTAHCDKLLLEN-------KELTQEASDMTLELKKHQEDIINCKK----------QEERMLKQIENLEEK 542
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1268 HKNLKSVLNNSKLE----QTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLE 1343
Cdd:pfam05483 543 EMNLRDELESVREEfiqkGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKK 622
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 1390011543 1344 Q-NMESKDLFHVEQRqyIDKLN-ELRRQKEKLEEkIMDQYK 1382
Cdd:pfam05483 623 KgSAENKQLNAYEIK--VNKLElELASAKQKFEE-IIDNYQ 660
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
726-1328 |
1.13e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 53.82 E-value: 1.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 726 ENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALE----NSNKKIQQLESELQDLEMENQTLQKSLE 801
Cdd:TIGR00618 164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPcmpdTYHERKQVLEKELKHLREALQQTQQSHA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 802 ELKisskRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT-----LEENNVKIGNLEKENKTLFKEINVY 876
Cdd:TIGR00618 244 YLT----QKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRArkaapLAAHIKAVTQIEQQAQRIHTELQSK 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 877 KEScvRLKELEKENKELVKRAtiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQStddsryKL 956
Cdd:TIGR00618 320 MRS--RAKLLMKRAAHVKQQS--SIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ------KT 389
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 957 LESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALK-QRQDEERMVQSSIPVSGEDDKWGRESQ 1035
Cdd:TIGR00618 390 TLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAElCAAAITCTAQCEKLEKIHLQESAQSLK 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1036 EATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVsLQEQNTTLQTQNAKLQVENSTLN 1115
Cdd:TIGR00618 470 EREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGP-LTRRMQRGEQTYAQLETSEEDVY 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1116 SQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKsahknLEVEH 1195
Cdd:TIGR00618 549 HQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALL-----RKLQP 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1196 KDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVAS--EYKKLCGENDRLNYTYSQLLKETeiLQMDHKNLKS 1273
Cdd:TIGR00618 624 EQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSirVLPKELLASRQLALQKMQSEKEQ--LTYWKEMLAQ 701
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 1274 VLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLL 1328
Cdd:TIGR00618 702 CQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVL 756
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
958-1299 |
2.08e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.15 E-value: 2.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 958 ESKLESTLKKsLEIKEEKIAALEARLEESTNYNQQLRHElKTVKKNYEALKQRQDEermvqssipvsgeddkwgRESQEA 1037
Cdd:TIGR02169 169 DRKKEKALEE-LEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKRE------------------YEGYEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1038 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNAKLQVENSTL-- 1114
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLer 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1115 -----NSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHK 1189
Cdd:TIGR02169 309 siaekERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1190 NLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEvvaSEYKKLCGENDRLNYTYSQLLKETEILQMDHK 1269
Cdd:TIGR02169 389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE---AKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
|
330 340 350
....*....|....*....|....*....|
gi 1390011543 1270 NLKSVLNNSKLEQTRLEAEFSKLKEQYQQL 1299
Cdd:TIGR02169 466 KYEQELYDLKEEYDRVEKELSKLQRELAEA 495
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
609-1374 |
2.39e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 52.74 E-value: 2.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 609 EKRQMKKELELYKEKGERAEELENEL----NHLGKENELLQKKITNLKITCEKLETLEQENS---ELERENRKFKKTLDS 681
Cdd:TIGR00606 201 KVQEHQMELKYLKQYKEKACEIRDQItskeAQLESSREIVKSYENELDPLKNRLKEIEHNLSkimKLDNEIKALKSRKKQ 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 682 FKNLTFQLESLEKENSQLDEENL---------ELRRSVESLKCASMRMAQLQLENKELESEKEQLR-------------- 738
Cdd:TIGR00606 281 MEKDNSELELKMEKVFQGTDEQLndlyhnhqrTVREKERELVDCQRELEKLNKERRLLNQEKTELLveqgrlqlqadrhq 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 739 ---KGLELMRASFKKTERLEVSYQGLDTENQ------RLQKALENSNKKIQQLESELQD--------------------- 788
Cdd:TIGR00606 361 ehiRARDSLIQSLATRLELDGFERGPFSERQiknfhtLVIERQEDEAKTAAQLCADLQSkerlkqeqadeirdekkglgr 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 789 -LEMENQTLQKSLEELKI----------SSKRLEQLEKENKSLEQETSQLEKDK--KQLEKENKRLRQQAEIKDTTLEEN 855
Cdd:TIGR00606 441 tIELKKEILEKKQEELKFvikelqqlegSSDRILELDQELRKAERELSKAEKNSltETLKKEVKSLQNEKADLDRKLRKL 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 856 NVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATI---DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHEL 932
Cdd:TIGR00606 521 DQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSllgYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKEL 600
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 933 EKIGLNKERLLHDEQSTDDSRYKL------------LESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKT- 999
Cdd:TIGR00606 601 ASLEQNKNHINNELESKEEQLSSYedklfdvcgsqdEESDLER-LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSc 679
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1000 ---VKKNYEALKQRQDEERMVQSSIPVSGEDdkwgresQEATRELLKVKDRLIEVERNNATLQA-EKQALKTQLKQLETQ 1075
Cdd:TIGR00606 680 cpvCQRVFQTEAELQEFISDLQSKLRLAPDK-------LKSTESELKKKEKRRDEMLGLAPGRQsIIDLKEKEIPELRNK 752
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1076 NNNLQAQIlalQRQTVSLQEQNTTLQTQNAKLQVENSTLNS---------QSTSLMNQNAQLL--IQQSSLENENESIMK 1144
Cdd:TIGR00606 753 LQKVNRDI---QRLKNDIEEQETLLGTIMPEEESAKVCLTDvtimerfqmELKDVERKIAQQAakLQGSDLDRTVQQVNQ 829
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1145 EREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQE 1224
Cdd:TIGR00606 830 EKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKE 909
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1225 KMLlesknheVVASEYKKLCGENDRLnytYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQY-QQLDITS 1303
Cdd:TIGR00606 910 QDS-------PLETFLEKDQQEKEEL---ISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYlKQKETEL 979
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 1304 TKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNR------TLLEQNMESKDLfHVEQRQYIDKLNELRRQKEKLE 1374
Cdd:TIGR00606 980 NTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERwlqdnlTLRKRENELKEV-EEELKQHLKEMGQMQVLQMKQE 1055
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
253-714 |
2.49e-06 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 52.60 E-value: 2.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAvrvDKLESELSRY 332
Cdd:PRK01156 185 IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMK---NRYESEIKTA 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 333 KERLHDIEFYKARVEELKEDNQVLLETKTM------------------LEDQLEGTRARSDKLHELEKENLQLKAKLHD- 393
Cdd:PRK01156 262 ESDLSMELEKNNYYKELEERHMKIINDPVYknrnyindyfkykndienKKQILSNIDAEINKYHAIIKKLSVLQKDYNDy 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 394 MEMERDMD--RKKIEELMEENM-------TLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELT------ 458
Cdd:PRK01156 342 IKKKSRYDdlNNQILELEGYEMdynsylkSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINvklqdi 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 459 SSKLLKLEMENQSLTKTVEELRSTADSAAG-----------STSKILKVEK----ENQRLNKKVEILENEI--IQEK--- 518
Cdd:PRK01156 422 SSKVSSLNQRIRALRENLDELSRNMEMLNGqsvcpvcgttlGEEKSNHIINhyneKKSRLEEKIREIEIEVkdIDEKivd 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 519 -------------QSLQNCQNLSKDLMKEKAQLEKTIETLRENSER-----------QIKILEQENEHLNQTVSslrQRS 574
Cdd:PRK01156 502 lkkrkeyleseeiNKSINEYNKIESARADLEDIKIKINELKDKHDKyeeiknrykslKLEDLDSKRTSWLNALA---VIS 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 575 QISAEARVKDIEKENKILHESIKETCGKLSKIEFEK-------RQMKKELELYKEKGERAEELENELNHLGKENELLQKK 647
Cdd:PRK01156 579 LIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKsyidksiREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQ 658
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1390011543 648 ITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEK----ENSQLDEENLELRRSVESLK 714
Cdd:PRK01156 659 IAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEilrtRINELSDRINDINETLESMK 729
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
347-580 |
2.57e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.07 E-value: 2.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 347 EELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDES 426
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 427 LHLGWELEQISRTSELAEApqkslghevneLTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKK 506
Cdd:COG4942 107 AELLRALYRLGRQPPLALL-----------LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1390011543 507 VEILENEIIQEKQSLQncqnlskDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Cdd:COG4942 176 LEALLAELEEERAALE-------ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
253-782 |
2.83e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 52.44 E-value: 2.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENmnllsdarsaRMYRDELDALREKAVRVDKLESELSRY 332
Cdd:pfam05557 99 LADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERL----------DLLKAKASEAEQLRQNLEKQQSSLAEA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 333 KERLHDIEF----YKARVEELKEDNQVLLETKTMlEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDmdrkKIEEL 408
Cdd:pfam05557 169 EQRIKELEFeiqsQEQDSEIVKNSKSELARIPEL-EKELERLREHNKHLNENIENKLLLKEEVEDLKRKLE----REEKY 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 409 MEENMTLEMaqkqsmdESLHLGWELEQISRTselaeAPQKSLGHEVNELTSSKLLKLEMENQSLtktVEELRStadsaag 488
Cdd:pfam05557 244 REEAATLEL-------EKEKLEQELQSWVKL-----AQDTGLNLRSPEDLSRRIEQLQQREIVL---KEENSS------- 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 489 STSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREnserqikILEQENEHLNQTVS 568
Cdd:pfam05557 302 LTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRA-------ILESYDKELTMSNY 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 569 SLRQRSQIsaearvkdiekenKILHESIKETCGKLSKIEFEKRQMKKELELYKekgERAEELENELNHLGKENELLQKKI 648
Cdd:pfam05557 375 SPQLLERI-------------EEAEDMTQKMQAHNEEMEAQLSVAEEELGGYK---QQAQTLERELQALRQQESLADPSY 438
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 649 TNLKITC--EKLETLEQENSELEREnrkfKKTLDSfknltfqleSLEKENSQLDEENLELRRSVESLKCASMRMAQLQLE 726
Cdd:pfam05557 439 SKEEVDSlrRKLETLELERQRLREQ----KNELEM---------ELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQ 505
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 727 NKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDT-ENQRLQKALENSNKKIQQL 782
Cdd:pfam05557 506 LEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMNFkEVLDLRKELESAELKNQRL 562
|
|
| SH3_and_anchor |
TIGR04211 |
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved ... |
716-826 |
3.08e-06 |
|
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.
Pssm-ID: 275056 [Multi-domain] Cd Length: 198 Bit Score: 50.01 E-value: 3.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 716 ASMRMAQLQLENKELESEKEQLRKglelmrasfkKTERLEVSYQGLDTENQRLQKALENSNK---KIQQLESELQDLEME 792
Cdd:TIGR04211 64 ARERLPELQQELAELQEELAELQE----------QLAELRQENQELKQQLSTLEAELEELQKeleRIKQISANAIELDEE 133
|
90 100 110
....*....|....*....|....*....|....
gi 1390011543 793 NQTLQKSLEELKissKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR04211 134 NRELREELAELK---QENEALEAENERLQENEQR 164
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
719-865 |
3.15e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 50.31 E-value: 3.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 719 RMAQLQLENKELESEKEQLRKGLELMRASFKKTE----RLEVSYQGLDTENQRLQKALEN--SNKKIQQLESELQDLEME 792
Cdd:COG1579 25 RLKELPAELAELEDELAALEARLEAAKTELEDLEkeikRLELEIEEVEARIKKYEEQLGNvrNNKEYEALQKEIESLKRR 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 793 NQTLQKSLEELkisskrLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKE 865
Cdd:COG1579 105 ISDLEDEILEL------MERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
792-1089 |
3.82e-06 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 50.72 E-value: 3.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 792 ENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFK 871
Cdd:pfam09728 2 AARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKKKQDQLQKEKDQLQSELSKAILAKSKLEKLCRELQK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 872 EINVYK-ESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD 950
Cdd:pfam09728 82 QNKKLKeESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELREKLKSLIEQYELRELHFEKLLKTK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 951 DSRYKLLESKLESTL----KKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQ------------RQDEE 1014
Cdd:pfam09728 162 ELEVQLAEAKLQQATeeeeKKAQEKEVAKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDtlnksnevfttfKKEME 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 1015 RMVQSSIPVSGEDDKWGRESQEATRELLKvkdrlievernnatLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Cdd:pfam09728 242 KMSKKIKKLEKENLTWKRKWEKSNKALLE--------------MAEERQKLKEELEKLQKKLEKLENLCRALQAE 302
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
252-822 |
4.12e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.22 E-value: 4.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNllSDARSARMYRDELDALREkavRVDKLESELSR 331
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLER---ELEERERRRAR 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 332 YKERLHDIEF---------------YKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHElEKENLQLK-----AKL 391
Cdd:COG4913 364 LEALLAALGLplpasaeefaalraeAAALLEALEEELEALEEALAEAEAALRDLRRELRELEA-EIASLERRksnipARL 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 392 HDM--EMERDMDRKKIE-----ELME---ENMTLEMA-------QKQSM-------------DESLHLGWEL-----EQI 436
Cdd:COG4913 443 LALrdALAEALGLDEAElpfvgELIEvrpEEERWRGAiervlggFALTLlvppehyaaalrwVNRLHLRGRLvyervRTG 522
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 437 SRTSELAEAPQKSLGHEVnELTSSKL---LKLEMENQ-SLTK--TVEELRSTADS--AAGSTSKILKV-EKENQRLN--- 504
Cdd:COG4913 523 LPDPERPRLDPDSLAGKL-DFKPHPFrawLEAELGRRfDYVCvdSPEELRRHPRAitRAGQVKGNGTRhEKDDRRRIrsr 601
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 505 --------KKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEK---TIETLRENSERQIKILEQENEhlnqtvssLRQr 573
Cdd:COG4913 602 yvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQErreALQRLAEYSWDEIDVASAERE--------IAE- 672
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 574 sqisAEARVKDIEKENKILhesiketcgklskiefekRQMKKELElykEKGERAEELENELNHLGKENELLQKKITNLKI 653
Cdd:COG4913 673 ----LEAELERLDASSDDL------------------AALEEQLE---ELEAELEELEEELDELKGEIGRLEKELEQAEE 727
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 654 TCEKLETLEQENSELEREnrkfkktldsfknltFQLESLEKENSQLDEENLElrrsveslkcASMRmAQLQLENKELESE 733
Cdd:COG4913 728 ELDELQDRLEAAEDLARL---------------ELRALLEERFAAALGDAVE----------RELR-ENLEERIDALRAR 781
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 734 KEQLRKGLELMRASFKKTERLEVSYQGLDTEN----QRLQKALENSN-----KKIQQL--ESELQDLEMENQTLQKSLEE 802
Cdd:COG4913 782 LNRAEEELERAMRAFNREWPAETADLDADLESlpeyLALLDRLEEDGlpeyeERFKELlnENSIEFVADLLSKLRRAIRE 861
|
650 660
....*....|....*....|
gi 1390011543 803 LKisskrlEQLEKENKSLEQ 822
Cdd:COG4913 862 IK------ERIDPLNDSLKR 875
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
550-982 |
6.65e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.31 E-value: 6.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH----ESIKETCGKLSKIEFEKRQMKKELELYKEKGE 625
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKleklLQLLPLYQELEALEAELAELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 626 RAEELENELNHLGKENELLQkkitnlkitcEKLETLEQENSELERENrkFKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Cdd:COG4717 157 ELRELEEELEELEAELAELQ----------EELEELLEQLSLATEEE--LQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 706 LRRSVESLKcasmRMAQLQLENKELESEKEQLR----------KGLELMRASFKKTERLEVSYQGLDTENQRLQKALENS 775
Cdd:COG4717 225 LEEELEQLE----NELEAAALEERLKEARLLLLiaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 776 NKKIQQLESELQDLEMENQTLQKSLEELKISskrleqlEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDttleen 855
Cdd:COG4717 301 GKEAEELQALPALEELEEEELEELLAALGLP-------PDLSPEELLELLDRIEELQELLREAEELEEELQLEE------ 367
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 856 nvkignLEKENKTLFKEINVYKE----SCVRLKELEKENKELVKRATIDIKTLVTLREDLvSEKLKTQQMNNDLEKLTHE 931
Cdd:COG4717 368 ------LEQEIAALLAEAGVEDEeelrAALEQAEEYQELKEELEELEEQLEELLGELEEL-LEALDEEELEEELEELEEE 440
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1390011543 932 LEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEAR 982
Cdd:COG4717 441 LEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEE 491
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
663-1016 |
7.15e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 51.44 E-value: 7.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 663 QENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLelrRSVESLKCASMR------MAQLQLENKELESEKEQ 736
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSL---RTVMELPQKSTSsdddhnRASMQRDEAIAAIDNEQ 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 737 LRKglelmrasfKKTERLEVSYQGLDtenqrLQKALENSNKKIQQLESE----LQDLE---MENQTLQKsleELKISSKR 809
Cdd:PLN02939 116 QTN---------SKDGEQLSDFQLED-----LVGMIQNAEKNILLLNQArlqaLEDLEkilTEKEALQG---KINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKE---- 885
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAEteer 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 886 ---LEKEN-------KELVKR---ATIDIKTLVTLREDLVSEKLKTQQMNndLEKLTHELEKIGLnkerLLHDEQSTDDS 952
Cdd:PLN02939 259 vfkLEKERslldaslRELESKfivAQEDVSKLSPLQYDCWWEKVENLQDL--LDRATNQVEKAAL----VLDQNQDLRDK 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1390011543 953 RYKLLESKLESTLKK----SLEIKEEKIAALEARL----EESTNYNQQLRHELKTVKKNYEALKQRQDEERM 1016
Cdd:PLN02939 333 VDKLEASLKEANVSKfssyKVELLQQKLKLLEERLqasdHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSL 404
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
334-652 |
7.62e-06 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 50.89 E-value: 7.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 334 ERLHDIEFYKARVEELKEDNQVL---LETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdMEMERDMDRKKIEELME 410
Cdd:pfam17380 286 ERQQQEKFEKMEQERLRQEKEEKareVERRRKLEEAEKARQAEMDRQAAIYAEQERMA-----MERERELERIRQEERKR 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 411 ENmtlEMAQKQSMDESLHLGWELEQISrtselAEAPQKS--LGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADSAAG 488
Cdd:pfam17380 361 EL---ERIRQEEIAMEISRMRELERLQ-----MERQQKNerVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEA 432
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 489 STSKILKVEKENQRLNKKVEILENEiiqEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHlnqtvs 568
Cdd:pfam17380 433 RQREVRRLEEERAREMERVRLEEQE---RQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE------ 503
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 569 slRQRSQISAEARVKDIEKENKILHESIKETcgKLSKIEFEKRQMKKELELYK---EKGERAEELENELNHLGKENELLQ 645
Cdd:pfam17380 504 --RKQAMIEEERKRKLLEKEMEERQKAIYEE--ERRREAEEERRKQQEMEERRriqEQMRKATEERSRLEAMEREREMMR 579
|
....*..
gi 1390011543 646 KKITNLK 652
Cdd:pfam17380 580 QIVESEK 586
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
577-695 |
9.13e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 50.55 E-value: 9.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 577 SAEARVKDIEKE-NKILHESIKE--TCGKLSKIEFEKRQMKKELELYKEKGERaeelENELNHLgkENELLQKKiTNLKi 653
Cdd:PRK12704 28 IAEAKIKEAEEEaKRILEEAKKEaeAIKKEALLEAKEEIHKLRNEFEKELRER----RNELQKL--EKRLLQKE-ENLD- 99
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1390011543 654 tcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKE 695
Cdd:PRK12704 100 --RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE 139
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
657-867 |
9.40e-06 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 50.21 E-value: 9.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 657 KLETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEENLELRRSVESLKcasmrmAQLQLENKELESEKEQ 736
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQA---ELEELNEEYNELQAELEALQAEIDKLQ------AEIAEAEAEIEERREE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 737 LRKgleLMRASFKK---TERLEV-----SYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKissK 808
Cdd:COG3883 88 LGE---RARALYRSggsVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELE---A 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1390011543 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:COG3883 162 LKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
491-695 |
1.45e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 50.01 E-value: 1.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 491 SKILKVEKENQRLNKKVEILENEI-IQEK----QSLQNCQNLSK--DLMKEKAQLEKTIETLRENSERQIKILEQENEHL 563
Cdd:PHA02562 174 DKIRELNQQIQTLDMKIDHIQQQIkTYNKnieeQRKKNGENIARkqNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 564 NQTVSSLRQrSQISAEARVKDIEKENKILHE---------SIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENEL 634
Cdd:PHA02562 254 SAALNKLNT-AAAKIKSKIEQFQKVIKMYEKggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEF 332
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 635 NHlgkenelLQKKITNLKitcEKLETLEQENSELERENRKFKKTL----DSFKNLTFQLESLEKE 695
Cdd:PHA02562 333 NE-------QSKKLLELK---NKISTNKQSLITLVDKAKKVKAAIeelqAEFVDNAEELAKLQDE 387
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
495-852 |
1.47e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 50.34 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 495 KVEKENQRLN----KKVEILENEII--QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERqikiLEQENEhlnqtVS 568
Cdd:PRK04863 301 QLAAEQYRLVemarELAELNEAESDleQDYQAASDHLNLVQTALRQQEKIERYQADLEELEER----LEEQNE-----VV 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 569 SLRQRSQISAEARVKDIEkenkilhESIKETCGKLSK-----IEFEKR--QMKKELELYkekgERAEELeNELNHLGKEN 641
Cdd:PRK04863 372 EEADEQQEENEARAEAAE-------EEVDELKSQLADyqqalDVQQTRaiQYQQAVQAL----ERAKQL-CGLPDLTADN 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 642 --ELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESlekenSQLDEENLELRRSVESLKCASMR 719
Cdd:PRK04863 440 aeDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSR-----SEAWDVARELLRRLREQRHLAEQ 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 720 MAQLQLENKELESEKEQLRKgLELMRASFKKteRLEVSYQG---LDTENQRLQKALENSN--------------KKIQQL 782
Cdd:PRK04863 515 LQQLRMRLSELEQRLRQQQR-AERLLAEFCK--RLGKNLDDedeLEQLQEELEARLESLSesvsearerrmalrQQLEQL 591
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 783 ESELQDLEM---ENQTLQKSLEELK------------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Cdd:PRK04863 592 QARIQRLAArapAWLAAQDALARLReqsgeefedsqdVTEYMQQLLERE-RELTVERDELAARKQALDEEIERLSQPGGS 670
|
....*
gi 1390011543 848 KDTTL 852
Cdd:PRK04863 671 EDPRL 675
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1033-1211 |
1.71e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.44 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1033 ESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQtvsLQEQNTTLQTQNAKLQVENS 1112
Cdd:COG3883 24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAE---IEERREELGERARALYRSGG 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1113 T-------LNSQSTS-----------LMNQNAQLLIQQSS----LENENESIMKEREDLKSLYDALIKDHEKLELLHERQ 1170
Cdd:COG3883 101 SvsyldvlLGSESFSdfldrlsalskIADADADLLEELKAdkaeLEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQ 180
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1390011543 1171 ASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQ 1211
Cdd:COG3883 181 EALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
656-859 |
1.85e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 49.63 E-value: 1.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 656 EKLETLEQENSELERENRKFKKTLDSF------KNLTFQLESLEKENSQLDEENLELRRSVESLKcASMRMAQLQLEN-- 727
Cdd:COG3206 182 EQLPELRKELEEAEAALEEFRQKNGLVdlseeaKLLLQQLSELESQLAEARAELAEAEARLAALR-AQLGSGPDALPEll 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 728 -----KELESEKEQLRKGLELMRASFKKTERlevSYQGLDTENQRLQKALENSNKKI-QQLESELQDLEMENQTLQKSLE 801
Cdd:COG3206 261 qspviQQLRAQLAELEAELAELSARYTPNHP---DVIALRAQIAALRAQLQQEAQRIlASLEAELEALQAREASLQAQLA 337
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1390011543 802 ELKISSKRLEQLEKENKSLEQEtsqLEKDKKQLEKENKRLrQQAEIkDTTLEENNVKI 859
Cdd:COG3206 338 QLEARLAELPELEAELRRLERE---VEVARELYESLLQRL-EEARL-AEALTVGNVRV 390
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
819-1158 |
2.17e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 49.35 E-value: 2.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL--------EENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKEN 890
Cdd:pfam05557 6 ESKARLSQLQNEKKQMELEHKRARIELEKKASALkrqldresDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 891 KELVKRATIDIKTLVTLREDLVSEK-----LKTQQMNNDLEKLTHELEKIGLNKErllHDEQSTDDSRYKLLESKLESTL 965
Cdd:pfam05557 86 EALNKKLNEKESQLADAREVISCLKnelseLRRQIQRAELELQSTNSELEELQER---LDLLKAKASEAEQLRQNLEKQQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 966 KKSLEiKEEKIAALEARLEESTNYNQqlrhELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVK 1045
Cdd:pfam05557 163 SSLAE-AEQRIKELEFEIQSQEQDSE----IVKNSKSELARIPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1046 DRLIEVERNNATLQAEKQALKTQLKQLEtqnNNLQAQILALqRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQN 1125
Cdd:pfam05557 238 EREEKYREEAATLELEKEKLEQELQSWV---KLAQDTGLNL-RSPEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKAR 313
|
330 340 350
....*....|....*....|....*....|...
gi 1390011543 1126 AQLLIQQSSLENENESIMKEREDLKSLYDALIK 1158
Cdd:pfam05557 314 RELEQELAQYLKKIEDLNKKLKRHKALVRRLQR 346
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
689-1073 |
2.22e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 49.12 E-value: 2.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 689 LESLEKENSQLDEENLELRRSVESLKcasMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSyqgLDTENQRL 768
Cdd:pfam07888 47 LQAQEAANRQREKEKERYKRDREQWE---RQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEE---LSEEKDAL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 769 QKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENkslEQETSQLEKDKKQLEKENKRLRQQAEIK 848
Cdd:pfam07888 121 LAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE---EAERKQLQAKLQQTEEELRSLSKEFQEL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 849 DTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKL 928
Cdd:pfam07888 198 RNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQAELHQA 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 929 THELEKIGLNkerllhdeqsTDDSRYKLLE-----SKLESTLKKSLEIKEEKIAAL-------EARLEESTNYNQQLRHE 996
Cdd:pfam07888 278 RLQAAQLTLQ----------LADASLALREgrarwAQERETLQQSAEADKDRIEKLsaelqrlEERLQEERMEREKLEVE 347
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 997 LKtvkknyealkqRQDEERMVQSSipvsgeddkwgresqEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Cdd:pfam07888 348 LG-----------REKDCNRVQLS---------------ESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLE 398
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
538-679 |
2.25e-05 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 49.47 E-value: 2.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 538 LEKTIETLRENSERQIkilEQENEHLNQTVSSLRQRsqISA-EARVKDIEKENKILHESIKEtcgKLSKIEfekrQMKKE 616
Cdd:COG2433 382 LEELIEKELPEEEPEA---EREKEHEERELTEEEEE--IRRlEEQVERLEAEVEELEAELEE---KDERIE----RLERE 449
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 617 LELYKEKGERAEELENELNHLGKENELLQKkitnlkitceKLETLEQENSELERENRKFKKTL 679
Cdd:COG2433 450 LSEARSEERREIRKDREISRLDREIERLER----------ELEEERERIEELKRKLERLKELW 502
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
685-1132 |
2.30e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 49.35 E-value: 2.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 685 LTFQLESLEKENSQLDEENLELRrsVESLKCASMRMAQLQLE---NKELESEKEQLRKGLELMRASFKKT-ERLEVSYQG 760
Cdd:pfam05557 7 SKARLSQLQNEKKQMELEHKRAR--IELEKKASALKRQLDREsdrNQELQKRIRLLEKREAEAEEALREQaELNRLKKKY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 761 LDTENQRLQ-----------------KALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQE 823
Cdd:pfam05557 85 LEALNKKLNekesqladarevisclkNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSS 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEEnNVKIGNLEKENKTLFKEINVYKEScvrlkeleKENKELVKRATIDIKT 903
Cdd:pfam05557 165 LAEAEQRIKELEFEIQSQEQDSEIVKNSKSE-LARIPELEKELERLREHNKHLNEN--------IENKLLLKEEVEDLKR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG--------------------LNKERLLHDEQSTDDSRYKLLEsKLES 963
Cdd:pfam05557 236 KLEREEKYREEAATLELEKEKLEQELQSWVKLAqdtglnlrspedlsrrieqlQQREIVLKEENSSLTSSARQLE-KARR 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 964 TLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEermVQSSIPVSGEDDKWGRESQEATRELLK 1043
Cdd:pfam05557 315 ELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILES---YDKELTMSNYSPQLLERIEEAEDMTQK 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1044 VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQilALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMN 1123
Cdd:pfam05557 392 MQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQ--ESLADPSYSKEEVDSLRRKLETLELERQRLREQKNELEM 469
|
....*....
gi 1390011543 1124 QNAQLLIQQ 1132
Cdd:pfam05557 470 ELERRCLQG 478
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
704-1222 |
2.69e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 2.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 704 LELRRSVESLKcasmRMAQLQLENKELESEKEQLRKGLELMRASFKKTErlevsYQGLDTENQRLQKALENSNKKIQQLE 783
Cdd:COG4913 245 EDAREQIELLE----PIRELAERYAAARERLAELEYLRAALRLWFAQRR-----LELLEAELEELRAELARLEAELERLE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 784 SELQDLEMENQTLQKS--------LEELKissKRLEQLEKENKSLEQETSQLEK-----------DKKQLEKENKRLRQQ 844
Cdd:COG4913 316 ARLDALREELDELEAQirgnggdrLEQLE---REIERLERELEERERRRARLEAllaalglplpaSAEEFAALRAEAAAL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 845 AEIKDTTLEENNVKIGNLEKENKTLFKEinvykescvrLKELEKENKELVKRA-TIDiKTLVTLREDLVSE-KLKTQQMN 922
Cdd:COG4913 393 LEALEEELEALEEALAEAEAALRDLRRE----------LRELEAEIASLERRKsNIP-ARLLALRDALAEAlGLDEAELP 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 923 ----------------------------------NDLEKLTHELEKIGLnKERLLHDEQSTDDSRYKLLESKLESTLKKs 968
Cdd:COG4913 462 fvgelievrpeeerwrgaiervlggfaltllvppEHYAAALRWVNRLHL-RGRLVYERVRTGLPDPERPRLDPDSLAGK- 539
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 969 LEIKEEKIAA-LEARLEESTNY-----NQQLRHELK------TVKKNYEAL-KQRQDEERmvqsSIPVSGEDdkwgresq 1035
Cdd:COG4913 540 LDFKPHPFRAwLEAELGRRFDYvcvdsPEELRRHPRaitragQVKGNGTRHeKDDRRRIR----SRYVLGFD-------- 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1036 eaTRELLKVKDRLIevernnATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAklqvenstln 1115
Cdd:COG4913 608 --NRAKLAALEAEL------AELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAERE---------- 669
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1116 sqstslmnqnaqllIQQssLENENESIMKEREDLKSLYDALikdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEH 1195
Cdd:COG4913 670 --------------IAE--LEAELERLDASSDDLAALEEQL----EELEAELEELEEELDELKGEIGRLEKELEQAEEEL 729
|
570 580
....*....|....*....|....*....
gi 1390011543 1196 KDLEDRYNQL--LKQKGQLEDLEKMIKTE 1222
Cdd:COG4913 730 DELQDRLEAAedLARLELRALLEERFAAA 758
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
498-713 |
2.77e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.61 E-value: 2.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 498 KENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQIKILEQENEHLNQTVSSLRQRsqis 577
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKE---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 578 AEARVKDIEKENKILHESIKE--TCGKLSKIEF-----EKRQMKKELELYK----EKGERAEELENELNHLGKENELLQK 646
Cdd:COG4942 92 IAELRAELEAQKEELAELLRAlyRLGRQPPLALllspeDFLDAVRRLQYLKylapARREQAEELRADLAELAALRAELEA 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 647 KITNLKitcEKLETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEENLELRRSVESL 713
Cdd:COG4942 172 ERAELE---ALLAELEEERAALEALKAERQKLLARLEK---ELAELAAELAELQQEAEELEALIARL 232
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
641-940 |
2.91e-05 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 49.45 E-value: 2.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 641 NELLQKKITNLKIT----CEKLETLEQENSELERENRKFKKTLDSFKNLTFQL-----ESLEKENSQLDEENLELRRSVE 711
Cdd:PRK00448 4 QEKFKKLLDQINIPddlqSEALESAEIEKVVVDKKSKKWEFHLKFPNILPIEDfklfkEKLKQSFSHIADIKVTFSIEVE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 712 SLKCasmrmaQLQLENKELESEKEQLRKGLELMRASFKKTE------RLEVSYQGlDTENQRL-QKALENSNKKIQQLES 784
Cdd:PRK00448 84 NITF------TEELLLDYWNEIIEKAKKNSPLFKSLLKKQKvevegnKLIIKVNN-EIERDHLkKKHLPKLIKQYEKFGF 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 785 ELqdLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK---------RLRQQAEI---KDTTL 852
Cdd:PRK00448 157 GI--LKIDFEIDDSKEELEKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDpkegpvqigKKIDKEEItpmKEINE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 853 EENNVKI-GNL------EKENKTLFKEINV--YKEScVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL-KTQQMN 922
Cdd:PRK00448 235 EERRVVVeGYVfkveikELKSGRHILTFKItdYTSS-IIVKKFSRDKEDLKKFDEIKKGDWVKVRGSVQNDTFtRDLVMN 313
|
330
....*....|....*....
gi 1390011543 923 -NDLEKLTHELEKIGLNKE 940
Cdd:PRK00448 314 aQDINEIKHPERKDTAEEE 332
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
719-896 |
3.46e-05 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 46.46 E-value: 3.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 719 RMAQLQLENKELESEKEQLRKGLELMRASfkKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQK 798
Cdd:pfam08614 15 RTALLEAENAKLQSEPESVLPSTSSSKLS--KASPQSASIQSLEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEK 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 799 SLEElkiSSKRLEQLEKENKSLEQEtsqlekdKKQLEKENKRLRQQAEIkdttleennvkignLEKENKTLFKEINVYKE 878
Cdd:pfam08614 93 KLRE---DERRLAALEAERAQLEEK-------LKDREEELREKRKLNQD--------------LQDELVALQLQLNMAEE 148
|
170
....*....|....*...
gi 1390011543 879 scvRLKELEKENKELVKR 896
Cdd:pfam08614 149 ---KLRKLEKENRELVER 163
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
575-837 |
3.50e-05 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 48.86 E-value: 3.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 575 QISAEARVKDIE---------KENKILHESIKETCGKLSKIEFEKRQMKKELELYKEkgeraeeLENELNHLGKEN-ELL 644
Cdd:PHA02562 146 QLSAPARRKLVEdlldisvlsEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNK-------NIEEQRKKNGENiARK 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 645 QKKITNLKitcEKLETLEQENSELERE----NRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCasmrM 720
Cdd:PHA02562 219 QNKYDELV---EEAKTIKAEIEELTDEllnlVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTC----T 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 721 AQLQLENKELESEKEQLRKGlelmrasfkkTERLEVSYQGLDTENQRLQKALENSnKKIQQLESelqDLEMENQTLQKSL 800
Cdd:PHA02562 292 QQISEGPDRITKIKDKLKEL----------QHSLEKLDTAIDELEEIMDEFNEQS-KKLLELKN---KISTNKQSLITLV 357
|
250 260 270
....*....|....*....|....*....|....*..
gi 1390011543 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Cdd:PHA02562 358 DKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKT 394
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
247-422 |
5.25e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.90 E-value: 5.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSAR-MYRDELDALREKAVRVDKL 325
Cdd:COG3883 26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERReELGERARALYRSGGSVSYL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 326 E-----SELSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL----HELEKENLQLKAKLH 392
Cdd:COG3883 106 DvllgsESFSDFLDRLSALskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELeaakAELEAQQAEQEALLA 185
|
170 180 190
....*....|....*....|....*....|
gi 1390011543 393 DMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Cdd:COG3883 186 QLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
759-896 |
5.41e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.84 E-value: 5.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 759 QGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQL--------------------EKENK 818
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEieevearikkyeeqlgnvrnNKEYE 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1390011543 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINvykescVRLKELEKENKELVKR 896
Cdd:COG1579 93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELD------EELAELEAELEELEAE 164
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
979-1213 |
5.68e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.09 E-value: 5.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 979 LEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEddkwgreSQEATRELLKVKDRLIEvernnatL 1058
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEE-------AKLLLQQLSELESQLAE-------A 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1059 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVsLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1138
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQE 310
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 1139 NESIMkerEDLKSLYDALIKDHEKLEllheRQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLE 1213
Cdd:COG3206 311 AQRIL---ASLEAELEALQAREASLQ----AQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
473-1164 |
5.86e-05 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 48.25 E-value: 5.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 473 TKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKD-------LMKEKAQLEKTIETL 545
Cdd:pfam01576 1 TRQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEaeemrarLAARKQELEEILHEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 546 R---ENSERQIKILEQENEHLNQTVSSL----------RQRSQI---SAEARVKDIEKENKILHEsiketcgKLSKIEFE 609
Cdd:pfam01576 81 EsrlEEEEERSQQLQNEKKKMQQHIQDLeeqldeeeaaRQKLQLekvTTEAKIKKLEEDILLLED-------QNSKLSKE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 610 KRQMKKELELYKEKGERAEELENELNHLGKENELLqkkITNLKitcEKLETLEQENSELERENRKFKKTL----DSFKNL 685
Cdd:pfam01576 154 RKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAM---ISDLE---ERLKKEEKGRQELEKAKRKLEGEStdlqEQIAEL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 686 TFQLESLEKENSQLDEenlELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEvsyQGLDTEN 765
Cdd:pfam01576 228 QAQIAELRAQLAKKEE---ELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQR---RDLGEEL 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 766 QRLQKALENS-----------NKKIQQLESELQDLEMENQTLQKSLEELKIssKRLEQLEKENKSLEQE---TSQLEKDK 831
Cdd:pfam01576 302 EALKTELEDTldttaaqqelrSKREQEVTELKKALEEETRSHEAQLQEMRQ--KHTQALEELTEQLEQAkrnKANLEKAK 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 832 KQLEKENKRLrqQAEIKdttleenNVKIGNLEKENKTLFKEINVyKESCVRLKELEKENKELVKRATidiktlvtlreDL 911
Cdd:pfam01576 380 QALESENAEL--QAELR-------TLQQAKQDSEHKRKKLEGQL-QELQARLSESERQRAELAEKLS-----------KL 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 912 VSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQStddsrykLLESKLESTLKKSLEIK--EEKIAALEARLEESTNY 989
Cdd:pfam01576 439 QSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQE-------LLQEETRQKLNLSTRLRqlEDERNSLQEQLEEEEEA 511
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 990 NQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEddKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQL 1069
Cdd:pfam01576 512 KRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKK--RLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDL 589
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1070 KQLETQNNNLQAQilalQRQTVSLQEQNTTLQTQNA----KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKE 1145
Cdd:pfam01576 590 DHQRQLVSNLEKK----QKKFDQMLAEEKAISARYAeerdRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAE 665
|
730
....*....|....*....
gi 1390011543 1146 REDLKSLYDALIKDHEKLE 1164
Cdd:pfam01576 666 MEDLVSSKDDVGKNVHELE 684
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
252-686 |
6.00e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 48.09 E-value: 6.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDarsarmyrdeldaLREKAVRVDKLESELSR 331
Cdd:TIGR04523 315 ELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRE-------------LEEKQNEIEKLKKENQS 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 332 YKERLHDIEFYKARVEelkednqvlletkTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:TIGR04523 382 YKQEIKNLESQINDLE-------------SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQ 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTsSKLLKLEMENQSLTKTVEELRSTADSaagSTS 491
Cdd:TIGR04523 449 DSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKE-KELKKLNEEKKELEEKVKDLTKKISS---LKE 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 492 KILKVEKENQRLNKKVEILENEIIQEKQSLQNCQnlskdLMKEKAQLEKTIETLRE--------NSERQIKILEQENEHL 563
Cdd:TIGR04523 525 KIEKLESEKKEKESKISDLEDELNKDDFELKKEN-----LEKEIDEKNKEIEELKQtqkslkkkQEEKQELIDQKEKEKK 599
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 564 NQTVSSLRQRSQISA-EARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKE-- 640
Cdd:TIGR04523 600 DLIKEIEEKEKKISSlEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDii 679
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1390011543 641 -------NELL---QKKITNlKITCEKLETLEQENSELERENRKFKKTLDSFKNLT 686
Cdd:TIGR04523 680 elmkdwlKELSlhyKKYITR-MIRIKDLPKLEEKYKEIEKELKKLDEFSKELENII 734
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
240-1015 |
6.58e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 48.03 E-value: 6.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 240 MKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDArsarmyRDELDALREKA 319
Cdd:PRK04863 275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQD----YQAA------SDHLNLVQTAL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 320 VRVDKLEselsRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARSDklhELEKENLQLKAKLHDMEMERD 399
Cdd:PRK04863 345 RQQEKIE----RYQADLEELE------ERLEEQNEVVEE----ADEQQEENEARAE---AAEEEVDELKSQLADYQQALD 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 400 MDRKKIEELMEENMTLEMAQKQSMDESLhlgwELEQISRTSELAEAPQKSLGHEVNELtSSKLLKLEMENQSLTKTVEEL 479
Cdd:PRK04863 408 VQQTRAIQYQQAVQALERAKQLCGLPDL----TADNAEDWLEEFQAKEQEATEELLSL-EQKLSVAQAAHSQFEQAYQLV 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 480 RSTAD----SAAGSTSKILKVEKENQR-LNKKVEILENEIIQEKQSLQNCQNLSK-----------------DLMKEKAQ 537
Cdd:PRK04863 483 RKIAGevsrSEAWDVARELLRRLREQRhLAEQLQQLRMRLSELEQRLRQQQRAERllaefckrlgknlddedELEQLQEE 562
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 538 LEKTIETL----RENSERQIKiLEQENEHLNQTVSSLRQRSQ--ISAEARVkdiekenkilhESIKETCGKlskiEFEKR 611
Cdd:PRK04863 563 LEARLESLsesvSEARERRMA-LRQQLEQLQARIQRLAARAPawLAAQDAL-----------ARLREQSGE----EFEDS 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 612 QMKkeLELYKEKGERAEELENELNHLGKENELLQKKITNLkitcekletLEQENSELERENR------------------ 673
Cdd:PRK04863 627 QDV--TEYMQQLLERERELTVERDELAARKQALDEEIERL---------SQPGGSEDPRLNAlaerfggvllseiyddvs 695
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 674 ------------------------KFKKTL-----------------DSFKNLTFQLESLEKENSQlDEENLELR----R 708
Cdd:PRK04863 696 ledapyfsalygparhaivvpdlsDAAEQLagledcpedlyliegdpDSFDDSVFSVEELEKAVVV-KIADRQWRysrfP 774
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 709 SVESLKCAS--MRMAQLQLENKELESEKEQLrkglelmRASFKKTERL--------------------EVSYQGLDTENQ 766
Cdd:PRK04863 775 EVPLFGRAAreKRIEQLRAEREELAERYATL-------SFDVQKLQRLhqafsrfigshlavafeadpEAELRQLNRRRV 847
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 767 RLQKALENSNKKIQQLESELQDLEMENQTLQKSL-------------------EELKISS----------KRLEQLEKEN 817
Cdd:PRK04863 848 ELERALADHESQEQQQRSQLEQAKEGLSALNRLLprlnlladetladrveeirEQLDEAEeakrfvqqhgNALAQLEPIV 927
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 818 KSLEQETS---QLEKDKKQLEKENKRLRQQAEIKDTTLE-------ENNVKIGNLEKENKTLFKEinvykescvRLKELE 887
Cdd:PRK04863 928 SVLQSDPEqfeQLKQDYQQAQQTQRDAKQQAFALTEVVQrrahfsyEDAAEMLAKNSDLNEKLRQ---------RLEQAE 998
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 888 KEN---KELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKlthELEKIGLN-----KERL------LHDEQSTDDSR 953
Cdd:PRK04863 999 QERtraREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQ---ELQDLGVPadsgaEERArarrdeLHARLSANRSR 1075
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1390011543 954 YKLLESKLESTlkksleikEEKIAALEARLEESTNYNQQLRHELKTVKKNY----EALKQRQDEER 1015
Cdd:PRK04863 1076 RNQLEKQLTFC--------EAEMDNLTKKLRKLERDYHEMREQVVNAKAGWcavlRLVKDNGVERR 1133
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
957-1120 |
6.99e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.52 E-value: 6.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 957 LESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDE--ERMVQSSIPVSGED------- 1027
Cdd:COG3883 35 AQAELDA-LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEraRALYRSGGSVSYLDvllgses 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1028 --------DKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTT 1099
Cdd:COG3883 114 fsdfldrlSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAA 193
|
170 180
....*....|....*....|.
gi 1390011543 1100 LQTQNAKLQVENSTLNSQSTS 1120
Cdd:COG3883 194 AEAQLAELEAELAAAEAAAAA 214
|
|
| mreC |
TIGR00219 |
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape ... |
825-943 |
7.54e-05 |
|
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped. Cells defective in MreC are round. Species with MreC include many of the Proteobacteria, Gram-positives, and spirochetes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 129323 [Multi-domain] Cd Length: 283 Bit Score: 46.78 E-value: 7.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEennVKIGNLEKENKTLFKEINVYKescvRLKElEKENKELVKRATIDIKTL 904
Cdd:TIGR00219 62 SENLKDVNNLEYENYKLRQELLKKNQQLE---ILTQNLKQENVRLRELLNSPL----SSDE-YKISAEVIYLNYDNYSTQ 133
|
90 100 110
....*....|....*....|....*....|....*....
gi 1390011543 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL 943
Cdd:TIGR00219 134 VVINKGFNDGVYKDMPVIADGKGLVGKVVSVGSNTSRVL 172
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
394-690 |
8.74e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 47.61 E-value: 8.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 394 MEMERD----MDRKK---IEELMEENMtLEMAQKQSMDESLHLGWELEQISRTSELAEapqkSLGHEVNELTSSKLLKLE 466
Cdd:PRK05771 4 VRMKKVlivtLKSYKdevLEALHELGV-VHIEDLKEELSNERLRKLRSLLTKLSEALD----KLRSYLPKLNPLREEKKK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 467 MENQSLtktvEELRSTADSAAGstskilKVEKENQRLNKKVEILENEI---IQEKQSLQNCQNLSKDLmkEKAQLEKTIE 543
Cdd:PRK05771 79 VSVKSL----EELIKDVEEELE------KIEKEIKELEEEISELENEIkelEQEIERLEPWGNFDLDL--SLLLGFKYVS 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 544 ----TLRENSERQIKILEQENEHLnqTVSSLRQRSQISAEARVKDIEKENKILhesiketcgklSKIEFEKRQMKKE--- 616
Cdd:PRK05771 147 vfvgTVPEDKLEELKLESDVENVE--YISTDKGYVYVVVVVLKELSDEVEEEL-----------KKLGFERLELEEEgtp 213
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 617 LELYKEKGERAEELENELNHLGKE-NELLQKKITNLKITCEKLETLEQENSELErenrKFKKTldsfkNLTFQLE 690
Cdd:PRK05771 214 SELIREIKEELEEIEKERESLLEElKELAKKYLEELLALYEYLEIELERAEALS----KFLKT-----DKTFAIE 279
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
729-926 |
8.82e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 47.61 E-value: 8.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 729 ELESEKEQLRKGLELMRASFKKT-----ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEEL 803
Cdd:PRK05771 47 KLRSLLTKLSEALDKLRSYLPKLnplreEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 804 K----ISSKrlEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT---------TLEENNVKIGNLEKEN---- 866
Cdd:PRK05771 127 EpwgnFDLD--LSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDkgyvyvvvvVLKELSDEVEEELKKLgfer 204
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 867 ------KTLFKEINVYKEscvRLKELEKE----NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Cdd:PRK05771 205 leleeeGTPSELIREIKE---ELEEIEKEreslLEELKELAKKYLEELLALYEYLEIELERAEALSKFLK 271
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
719-837 |
8.92e-05 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 44.22 E-value: 8.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 719 RMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLEselQDLEMENQTLQK 798
Cdd:pfam12718 22 KVKELEQENLEKEQEIKSLTHKNQQLEEEVEKLEEQLKEAKEKAEESEKLKTNNENLTRKIQLLE---EELEESDKRLKE 98
|
90 100 110
....*....|....*....|....*....|....*....
gi 1390011543 799 SLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Cdd:pfam12718 99 TTEKLRETDVKAEHLERKVQALEQERDEWEKKYEELEEK 137
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
734-1073 |
9.05e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 46.82 E-value: 9.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 734 KEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLemeNQTLQKSLEELKISSKRLEQL 813
Cdd:COG4372 30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL---NEQLQAAQAELAQAQEELESL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLK--ELEKENK 891
Cdd:COG4372 107 QEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSeaEAEQALD 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 892 ELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEI 971
Cdd:COG4372 187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELA 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 972 KEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEV 1051
Cdd:COG4372 267 ILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLL 346
|
330 340
....*....|....*....|..
gi 1390011543 1052 ERNNATLQAEKQALKTQLKQLE 1073
Cdd:COG4372 347 LVGLLDNDVLELLSKGAEAGVA 368
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
464-671 |
9.19e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 47.07 E-value: 9.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 464 KLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLqncqnlsKDLMKEKAQLEKTIE 543
Cdd:COG4942 28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAEL-------AELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 544 TLRENSERQIKILeQENEHLNQTVSSLRQRSQISAEAR---VKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELE-L 619
Cdd:COG4942 101 AQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEaL 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1390011543 620 YKEKGERAEELENELNhlgKENELLQKKITNLKITCEKLETLEQENSELERE 671
Cdd:COG4942 180 LAELEEERAALEALKA---ERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
571-846 |
9.38e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 47.64 E-value: 9.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 571 RQRSQISAE-ARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKE-----LELYKEKGERAEELENELNHLGKENELL 644
Cdd:COG3096 843 QRRSELERElAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADEtladrLEELREELDAAQEAQAFIQQHGKALAQL 922
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 645 QKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENS-QLDEENLELrrsVESLKcasmrmAQL 723
Cdd:COG3096 923 EPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAvGLLGENSDL---NEKLR------ARL 993
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 724 qlenKELESEKEQLRkglelmrasfkktERLEVSYQGLDTENQRLQK---ALENSNKKIQQLESELQDL------EMENQ 794
Cdd:COG3096 994 ----EQAEEARREAR-------------EQLRQAQAQYSQYNQVLASlksSRDAKQQTLQELEQELEELgvqadaEAEER 1056
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 795 TLQKSLE---ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG3096 1057 ARIRRDElheELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVV 1111
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
262-383 |
1.07e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 47.38 E-value: 1.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 262 RLRQELEEKTEQLLDCKQELEQIEVELKRLQQENmNLLSDARSARmYRDELDALREkavrvdKLESELSRYKERLHDIEf 341
Cdd:COG0542 401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQ-DEASFERLAE-LRDELAELEE------ELEALKARWEAEKELIE- 471
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1390011543 342 ykaRVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Cdd:COG0542 472 ---EIQELKEELEQRYGKIPELEKELAELEEELAELAPLLRE 510
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
519-1082 |
1.17e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 519 QSLQNCQNLS---KDLMKEKAQLEKTIETLREN-------------SERQIKILEQENEH---LNQTVSSLRQRSQISAE 579
Cdd:COG4913 201 QSFKPIGDLDdfvREYMLEEPDTFEAADALVEHfddlerahealedAREQIELLEPIRELaerYAAARERLAELEYLRAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 580 ARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEK------------GERAEELENELNHLGKENELLQKK 647
Cdd:COG4913 281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEldeleaqirgngGDRLEQLEREIERLERELEERERR 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 648 ITNLKITCEKLE-TLEQENSELERENRKFKKTLDSFKNLTFQLES-----------LEKENSQLDEE--NLELRRSVESL 713
Cdd:COG4913 361 RARLEALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALEEalaeaeaalrdLRRELRELEAEiaSLERRKSNIPA 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 714 KCASMRMA---QLQLENKEL---------ESEKEQLRKGLELMRASFKKT-------------------ERLEVSYQGLD 762
Cdd:COG4913 441 RLLALRDAlaeALGLDEAELpfvgelievRPEEERWRGAIERVLGGFALTllvppehyaaalrwvnrlhLRGRLVYERVR 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 763 T--ENQRLQKALENS-NKKIQQLESELQD-LEMEnqtLQKSLEELKISSkrLEQLEKENKSLEQE------TSQLEKDKK 832
Cdd:COG4913 521 TglPDPERPRLDPDSlAGKLDFKPHPFRAwLEAE---LGRRFDYVCVDS--PEELRRHPRAITRAgqvkgnGTRHEKDDR 595
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 833 QLEKENKRLRQQAEikdttleennVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKELVKRATiDIKTLVTLREDLV 912
Cdd:COG4913 596 RRIRSRYVLGFDNR----------AKLAALEAELAELEEELAEAEE---RLEALEAELDALQERRE-ALQRLAEYSWDEI 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 913 seklktqqmnnDLEKLTHELEKIGLNKERLlhdEQSTDDSRykllesklesTLKKSLEIKEEKIAALEARLEEstnynqq 992
Cdd:COG4913 662 -----------DVASAEREIAELEAELERL---DASSDDLA----------ALEEQLEELEAELEELEEELDE------- 710
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 993 LRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDdkWGRESQEATRELLKVKDRLIEVERNnatLQAEKQALKTQLKQL 1072
Cdd:COG4913 711 LKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL--ELRALLEERFAAALGDAVERELREN---LEERIDALRARLNRA 785
|
650
....*....|
gi 1390011543 1073 ETQNNNLQAQ 1082
Cdd:COG4913 786 EEELERAMRA 795
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
622-714 |
1.17e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 47.16 E-value: 1.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 622 EKGERAEELENELNHLGKENELLQKKITNLKITCEKLET-LEQENSELERENRKFKKtldsFKNLTFQLESLEKENSQLD 700
Cdd:COG2433 410 EEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLEReLSEARSEERREIRKDRE----ISRLDREIERLERELEEER 485
|
90
....*....|....
gi 1390011543 701 EENLELRRSVESLK 714
Cdd:COG2433 486 ERIEELKRKLERLK 499
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
531-844 |
1.23e-04 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 46.75 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 531 LMKEKAQLEKTIETLRENSERQIKILEQenehLNQTVSSLRQRSQISAEARV------KDIEKENKILHESIKETCGKLS 604
Cdd:PRK04778 100 FRKAKHEINEIESLLDLIEEDIEQILEE----LQELLESEEKNREEVEQLKDlyrelrKSLLANRFSFGPALDELEKQLE 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 605 KIEfEKRQMKKELelyKEKGERAE------ELENELNHLGKenelLQKKITNLKITCEK-----LETLEQENSELERENR 673
Cdd:PRK04778 176 NLE-EEFSQFVEL---TESGDYVEareildQLEEELAALEQ----IMEEIPELLKELQTelpdqLQELKAGYRELVEEGY 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 674 KFKKtldsfKNLTFQLESLEKENSQLDE--ENLELRRSVESLKCASMRMAQL--QLEN-----KELESEKEQLRKGLELM 744
Cdd:PRK04778 248 HLDH-----LDIEKEIQDLKEQIDENLAllEELDLDEAEEKNEEIQERIDQLydILERevkarKYVEKNSDTLPDFLEHA 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 745 RASFK----KTERLEVSYQgLDTENQRLQKALEnsnKKIQQLESELQDL--EMENQTLQKSL--EELKISSKRLEQLEKE 816
Cdd:PRK04778 323 KEQNKelkeEIDRVKQSYT-LNESELESVRQLE---KQLESLEKQYDEIteRIAEQEIAYSElqEELEEILKQLEEIEKE 398
|
330 340
....*....|....*....|....*...
gi 1390011543 817 NKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:PRK04778 399 QEKLSEMLQGLRKDELEAREKLERYRNK 426
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
728-1365 |
1.24e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 1.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 728 KELESEKEQLRKgLELMRASFKKTERLEVSYQGLDTENQRL-----QKALENSNKKIQQLESELQDLEMENQTLQKSLEE 802
Cdd:COG4913 242 EALEDAREQIEL-LEPIRELAERYAAARERLAELEYLRAALrlwfaQRRLELLEAELEELRAELARLEAELERLEARLDA 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 803 LKISSKRLEQLEKENKSleQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEInvyKESCVR 882
Cdd:COG4913 321 LREELDELEAQIRGNGG--DRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA---AALLEA 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 883 LKELEKENKELVKRATIDIKTLVTLREDLVSEK--LKTQQMNND--LEKLTHEL-EKIGLNK------------------ 939
Cdd:COG4913 396 LEEELEALEEALAEAEAALRDLRRELRELEAEIasLERRKSNIParLLALRDALaEALGLDEaelpfvgelievrpeeer 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 940 -----ERLLH--------DEQ-----------------------STDDSRYKLLESKLESTLKKsLEIKEEKIAA-LEAR 982
Cdd:COG4913 476 wrgaiERVLGgfaltllvPPEhyaaalrwvnrlhlrgrlvyervRTGLPDPERPRLDPDSLAGK-LDFKPHPFRAwLEAE 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 983 LEESTNY-----NQQLRHELK------TVKKNYEAL-KQRQDEERmvqsSIPVSGEDdkwgresqeaTRELLKVKDRLIe 1050
Cdd:COG4913 555 LGRRFDYvcvdsPEELRRHPRaitragQVKGNGTRHeKDDRRRIR----SRYVLGFD----------NRAKLAALEAEL- 619
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1051 vernnATLQAEKQALKTQLKQLETQNNNLQAQILALQRqtvslqeqnttlqtqnaklqvenstlnsqstslmnqnaqlLI 1130
Cdd:COG4913 620 -----AELEEELAEAEERLEALEAELDALQERREALQR----------------------------------------LA 654
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1131 QQSSLENENESIMKEREDLKSLYDALIKDHEKLELLhERQASEyesliskhgtlksahknLEVEHKDLEDRYNQLLKQKG 1210
Cdd:COG4913 655 EYSWDEIDVASAEREIAELEAELERLDASSDDLAAL-EEQLEE-----------------LEAELEELEEELDELKGEIG 716
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1211 QLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLNYTYSQLLKE-TEILQMDHKNLKSVLNNsklEQTRLEAEF 1289
Cdd:COG4913 717 RLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERElRENLEERIDALRARLNR---AEEELERAM 793
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1290 SKLKEQY----QQLDITSTKLNNQCELLSQLKGN-LEEENRHLLDQIQTLMLQNRTLLEQNMESkDLFHVEQRqyIDKLN 1364
Cdd:COG4913 794 RAFNREWpaetADLDADLESLPEYLALLDRLEEDgLPEYEERFKELLNENSIEFVADLLSKLRR-AIREIKER--IDPLN 870
|
.
gi 1390011543 1365 E 1365
Cdd:COG4913 871 D 871
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
716-878 |
1.33e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.36 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 716 ASMRMAQLQLENKELESEKEQLRKglelmrasfkKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQT 795
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQA----------ELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 796 LQKSLEEL----------------------------------KISS---KRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:COG3883 84 RREELGERaralyrsggsvsyldvllgsesfsdfldrlsalsKIADadaDLLEELKADKAELEAKKAELEAKLAELEALK 163
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1390011543 839 KRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKE 878
Cdd:COG3883 164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEA 203
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
251-408 |
1.37e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.30 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 251 VELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDARSA-RMYRDELDALREKAVRVDKLESEL 329
Cdd:COG1579 10 LDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTE----LEDLEKEiKRLELEIEEVEARIKKYEEQLGNV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 330 SRYKER---LHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL-HELEKENLQLKAKLHDMEMERDMDRKKI 405
Cdd:COG1579 86 RNNKEYealQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELeAELEEKKAELDEELAELEAELEELEAER 165
|
...
gi 1390011543 406 EEL 408
Cdd:COG1579 166 EEL 168
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
241-642 |
1.40e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 47.20 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNllsDARSARMYRDEldalreKAV 320
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDD---DHNRASMQRDE------AIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 321 RVDKLESELSRYKERLHDIEFykarvEELKEDNQVLlETKTMLEDQlegtrARSDKLHELEK---ENLQLKAKLHDMEME 397
Cdd:PLN02939 110 AIDNEQQTNSKDGEQLSDFQL-----EDLVGMIQNA-EKNILLLNQ-----ARLQALEDLEKiltEKEALQGKINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 398 RDMDRKKIEELMEENMTLEMAQKQsmdeslhLGWELEQISRTSELAEAPQKSLGHEVNELTSskllklemENQSLTKTVE 477
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQ-------LEKLRNELLIRGATEGLCVHSLSKELDVLKE--------ENMLLKDDIQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 478 ELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQ-LEKTIETLRENSERQIKIL 556
Cdd:PLN02939 244 FLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVEnLQDLLDRATNQVEKAALVL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 557 EQeNEHLNQTVSSLRQRsqiSAEARVKDIEKEN-KILHESIKETCGKLSKIEFEkrqMKKELELYKEKgerAEELENELN 635
Cdd:PLN02939 324 DQ-NQDLRDKVDKLEAS---LKEANVSKFSSYKvELLQQKLKLLEERLQASDHE---IHSYIQLYQES---IKEFQDTLS 393
|
....*..
gi 1390011543 636 HLGKENE 642
Cdd:PLN02939 394 KLKEESK 400
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
768-872 |
1.45e-04 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 45.88 E-value: 1.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 768 LQKALENSNKKIQQLESELQDLEMENQTLQksleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEi 847
Cdd:COG4026 133 LREELLELKEKIDEIAKEKEKLTKENEELE----------SELEELREEYKKLREENSILEEEFDNIKSEYSDLKSRFE- 201
|
90 100
....*....|....*....|....*
gi 1390011543 848 kdTTLEENNVKIGNLEKENKTLFKE 872
Cdd:COG4026 202 --ELLKKRLLEVFSLEELWKELFPE 224
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
974-1176 |
1.69e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 974 EKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQ--RQDEERMVQSSipvsgeddkwgRESQEATRELLKVKDRLIEV 1051
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKqlAALERRIAALA-----------RRIRALEQELAALEAELAEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1052 ERNNATLQAEKQALKTQLKQ--------------------------------LETQNNNLQAQILALQRQTVSLQEQNTT 1099
Cdd:COG4942 89 EKEIAELRAELEAQKEELAEllralyrlgrqpplalllspedfldavrrlqyLKYLAPARREQAEELRADLAELAALRAE 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 1100 LQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYES 1176
Cdd:COG4942 169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
779-869 |
1.76e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 46.61 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 779 IQQLESELQDLEMENQTLQKslEELKISSKRLEQLEKENKSLEQETSQLekdKKQLEKENKRLRQQAEIKDtTLEENNVK 858
Cdd:COG0542 413 LDELERRLEQLEIEKEALKK--EQDEASFERLAELRDELAELEEELEAL---KARWEAEKELIEEIQELKE-ELEQRYGK 486
|
90
....*....|.
gi 1390011543 859 IGNLEKENKTL 869
Cdd:COG0542 487 IPELEKELAEL 497
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
246-391 |
2.28e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.92 E-value: 2.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 246 RQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQ---ENMNLLSDARSARMYRD---ELDALREka 319
Cdd:COG1579 26 LKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEArikKYEEQLGNVRNNKEYEAlqkEIESLKR-- 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 320 vRVDKLESELSRYKERlhdIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDK-LHELEKENLQLKAKL 391
Cdd:COG1579 104 -RISDLEDEILELMER---IEELEEELAELEAELAELEAELEEKKAELDEELAELEAeLEELEAEREELAAKI 172
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
529-1225 |
3.18e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.10 E-value: 3.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 529 KDLMKEKAQLEKTIETLRENSERQiKILEQE----NEHLNQTVSSLRQRSQI--------SAEARVKDIEKENKILHESI 596
Cdd:COG3096 299 RQLAEEQYRLVEMARELEELSARE-SDLEQDyqaaSDHLNLVQTALRQQEKIeryqedleELTERLEEQEEVVEEAAEQL 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 597 KETCGKLSKIEFEKRQMKKELELYK----EKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELEREN 672
Cdd:COG3096 378 AEAEARLEAAEEEVDSLKSQLADYQqaldVQQTRAIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEV 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 673 RKFKKTLDSFKNLTFQ----LESLEK-----ENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLEL 743
Cdd:COG3096 458 LELEQKLSVADAARRQfekaYELVCKiagevERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERL 537
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 744 MRASFKKT-------ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTL----------QKSLEELK-- 804
Cdd:COG3096 538 LEEFCQRIgqqldaaEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELaarapawlaaQDALERLReq 617
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 805 ----------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLeennvkIGNLEKENKTLFKE-- 872
Cdd:COG3096 618 sgealadsqeVTAAMQQLLERE-REATVERDELAARKQALESQIERLSQPGGAEDPRL------LALAERLGGVLLSEiy 690
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 873 ---------------------INVYKESCVR--LKELEK--ENKELVKR--ATIDIKTLVTLR-EDLVSEKLKTQQM--- 921
Cdd:COG3096 691 ddvtledapyfsalygparhaIVVPDLSAVKeqLAGLEDcpEDLYLIEGdpDSFDDSVFDAEElEDAVVVKLSDRQWrys 770
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 922 -------------NNDLEKLTHELEKIGlnkERllHDEQSTDDSRYKLLESKLESTLKKSLEI-----KEEKIAALEARL 983
Cdd:COG3096 771 rfpevplfgraarEKRLEELRAERDELA---EQ--YAKASFDVQKLQRLHQAFSQFVGGHLAVafapdPEAELAALRQRR 845
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 984 EESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGR---------ESQEATRELLKVKDRLIEVERN 1054
Cdd:COG3096 846 SELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQANLLADETLADRleelreeldAAQEAQAFIQQHGKALAQLEPL 925
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1055 NATLQAEKQ---ALKTQLKQLETQNNNLQAQILAL----QRQT-------VSLQEQNTTLQTQ-NAKLQVENSTLNSQST 1119
Cdd:COG3096 926 VAVLQSDPEqfeQLQADYLQAKEQQRRLKQQIFALsevvQRRPhfsyedaVGLLGENSDLNEKlRARLEQAEEARREARE 1005
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1120 SLMNQNAQLliqqsslenenESIMKEREDLKSLYDAliKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLE 1199
Cdd:COG3096 1006 QLRQAQAQY-----------SQYNQVLASLKSSRDA--KQQTLQELEQELEELGVQADAEAEERARIRRDELHEELSQNR 1072
|
810 820 830
....*....|....*....|....*....|
gi 1390011543 1200 DRYNQLLKQKG----QLEDLEKMIKTEQEK 1225
Cdd:COG3096 1073 SRRSQLEKQLTrceaEMDSLQKRLRKAERD 1102
|
|
| Uso1_p115_C |
pfam04871 |
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular ... |
777-867 |
3.32e-04 |
|
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein, this myosin-shaped molecule consists of an N-terminal globular head region, a coiled-coil tail which mediates dimerization, and a short C-terminal acidic region. p115 tethers COP1 vesicles to the Golgi by binding the coiled coil proteins giantin (on the vesicles) and GM130 (on the Golgi), via its C-terminal acidic region. It is required for intercisternal transport in the golgi stack. This family consists of the acidic C-terminus, which binds to the golgins giantin and GM130. p115 is thought to juxtapose two membranes by binding giantin with one acidic region, and GM130 with another.
Pssm-ID: 461461 [Multi-domain] Cd Length: 121 Bit Score: 42.39 E-value: 3.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 777 KKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Cdd:pfam04871 1 AKKSELESEASSLKNENTELKAELQELSKQYNSLEQKESQAKELEAEVKKLEEALKKLKAELSEEKQKEKEKQSELDDLL 80
|
90
....*....|.
gi 1390011543 857 VKIGNLEKENK 867
Cdd:pfam04871 81 LLLGDLEEKVE 91
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
752-1020 |
3.46e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.78 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 752 ERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSlEELKISSKRLEQlekenksLEQETSQLEKDK 831
Cdd:COG3206 164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLS-EEAKLLLQQLSE-------LESQLAEARAEL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 832 KQLEKENKRLRQQAEIKDTTLEE--NNVKIGNLEKenktlfkeinvykescvRLKELEKENKELVKRATIDIKTLVTLRe 909
Cdd:COG3206 236 AEAEARLAALRAQLGSGPDALPEllQSPVIQQLRA-----------------QLAELEAELAELSARYTPNHPDVIALR- 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 910 dlvseklktQQMNNDLEKLTHELEKIGLNKErllhdeqstddSRYKLLESKLEStLKKSLEIKEEKIAALEARLEEStny 989
Cdd:COG3206 298 ---------AQIAALRAQLQQEAQRILASLE-----------AELEALQAREAS-LQAQLAQLEARLAELPELEAEL--- 353
|
250 260 270
....*....|....*....|....*....|.
gi 1390011543 990 nQQLRHELKTVKKNYEALKQRQDEERMVQSS 1020
Cdd:COG3206 354 -RRLEREVEVARELYESLLQRLEEARLAEAL 383
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
528-858 |
3.48e-04 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 45.33 E-value: 3.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISA----EARVKDIEKENKILHESIKETCGKL 603
Cdd:COG5185 273 NAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKATESLEEQLAAAEAeqelEESKRETETGIQNLTAEIEQGQESL 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 604 SKIEFEKRQMKKELELYKEKGERAEELENELNHL-GKENELLQKKITNLKITCEKLETLEQENSELERENrkfkktldsf 682
Cdd:COG5185 353 TENLEAIKEEIENIVGEVELSKSSEELDSFKDTIeSTKESLDEIPQNQRGYAQEILATLEDTLKAADRQI---------- 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 683 KNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLD 762
Cdd:COG5185 423 EELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLE 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 763 TENQRLQKALENSNKKIQQLESELQDLEMENQTLQKsleelkisskrlEQLEKENKSLEQETSQLEKDKKQLEKENKRLR 842
Cdd:COG5185 503 KLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHI------------LALENLIPASELIQASNAKTDGQAANLRTAVI 570
|
330
....*....|....*.
gi 1390011543 843 QQAEIKDTTLEENNVK 858
Cdd:COG5185 571 DELTQYLSTIESQQAR 586
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1036-1377 |
3.53e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.82 E-value: 3.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1036 EATRE-LLKVKDRLIEVERNNATLQaeKQALKTQ-LKQLETQNNNLQAQILALQRQtvSLQEQNTTLQTQNAKLQVENST 1113
Cdd:TIGR02168 182 ERTREnLDRLEDILNELERQLKSLE--RQAEKAErYKELKAELRELELALLVLRLE--ELREELEELQEELKEAEEELEE 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1114 LNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALikdHEKLELLHERQaseyesliskhgtlksahKNLEV 1193
Cdd:TIGR02168 258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL---EQQKQILRERL------------------ANLER 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1194 EHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEkMLLESKNhevvaseykklcgendrlnytysQLLKETEILQMDHKNLKS 1273
Cdd:TIGR02168 317 QLEELEAQLEELESKLDELAEELAELEEKLE-ELKEELE-----------------------SLEAELEELEAELEELES 372
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1274 VLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQ--NRTLLEQNMESKDL 1351
Cdd:TIGR02168 373 RLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKelQAELEELEEELEEL 452
|
330 340
....*....|....*....|....*.
gi 1390011543 1352 FHvEQRQYIDKLNELRRQKEKLEEKI 1377
Cdd:TIGR02168 453 QE-ELERLEEALEELREELEEAEQAL 477
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
257-586 |
3.72e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 45.50 E-value: 3.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 257 KAKIRRLRQELEEKTEQlLDCKQELEQIEvelkRLQQENMNllsdaRSARMYRDELDALREKavrvdklESELSRYKERL 336
Cdd:pfam17380 295 KMEQERLRQEKEEKARE-VERRRKLEEAE----KARQAEMD-----RQAAIYAEQERMAMER-------ERELERIRQEE 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 337 HDIEFYKARVEELKednqvlLETKTMLEdqLEGTRARSDKLHELEKENLQLKAKLHDMEMERdmdRKKIEELMEENMTLE 416
Cdd:pfam17380 358 RKRELERIRQEEIA------MEISRMRE--LERLQMERQQKNERVRQELEAARKVKILEEER---QRKIQQQKVEMEQIR 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 417 MAQKQSMDESLHL-----GWELEQIsRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSlTKTVEELRSTADSAAGSTS 491
Cdd:pfam17380 427 AEQEEARQREVRRleeerAREMERV-RLEEQERQQQVERLRQQEEERKRKKLELEKEKRD-RKRAEEQRRKILEKELEER 504
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 492 KILKVEKENQR--LNKKVEILENEIIQEKQSLQNCQNLSKDL-MKEKAQLEKTIETLRENSERqIKILEQENEHLNQTVS 568
Cdd:pfam17380 505 KQAMIEEERKRklLEKEMEERQKAIYEEERRREAEEERRKQQeMEERRRIQEQMRKATEERSR-LEAMEREREMMRQIVE 583
|
330
....*....|....*...
gi 1390011543 569 SLRQRSQISAEARVKDIE 586
Cdd:pfam17380 584 SEKARAEYEATTPITTIK 601
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
602-887 |
4.35e-04 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 44.80 E-value: 4.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 602 KLSKIEFEKRQMKKELELYKEKgeraeELENELNHLGKENELLQKKITNLKitcekletleqenSELERENRKFKKTLDS 681
Cdd:pfam15905 55 KVKSLELKKKSQKNLKESKDQK-----ELEKEIRALVQERGEQDKRLQALE-------------EELEKVEAKLNAAVRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 682 FKNLTFQLESLEKENSQLDEENlELRRSVESLKCASMRMAQLQLENKELESEKEqlrkglelmrasfKKTERLEVSYQGL 761
Cdd:pfam15905 117 KTSLSASVASLEKQLLELTRVN-ELLKAKFSEDGTQKKMSSLSMELMKLRNKLE-------------AKMKEVMAKQEGM 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 762 DTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Cdd:pfam15905 183 EGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEIESL 262
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1390011543 842 RQQAEIKDTTLEEN----NVKIGNLEKENKTLFKEINVYKEScvRLKELE 887
Cdd:pfam15905 263 KQSLEEKEQELSKQikdlNEKCKLLESEKEELLREYEEKEQT--LNAELE 310
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
1036-1114 |
4.50e-04 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 43.00 E-value: 4.50e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1390011543 1036 EATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Cdd:pfam08614 82 DLNEELQELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEEKLRKLEKENREL 160
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
247-408 |
4.66e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 4.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSAR------MYRDELDALREKAV 320
Cdd:COG4913 688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELralleeRFAAALGDAVEREL 767
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 321 RvDKLESELSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDqLEGTRAR-----SDKLHELEKENLQLKAK--- 390
Cdd:COG4913 768 R-ENLEERIDALRARLNRAEeeLERAMRAFNREWPAETADLDADLES-LPEYLALldrleEDGLPEYEERFKELLNEnsi 845
|
170 180
....*....|....*....|....
gi 1390011543 391 ------LHDMEMERDMDRKKIEEL 408
Cdd:COG4913 846 efvadlLSKLRRAIREIKERIDPL 869
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
839-1013 |
5.65e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.76 E-value: 5.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 839 KRLRQQAEIkDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLvSEKLKT 918
Cdd:COG1579 7 RALLDLQEL-DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKY-EEQLGN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 919 QQMNNDLEKLTHELEKIGLNKERLlhdeqstdDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTnynQQLRHELK 998
Cdd:COG1579 85 VRNNKEYEALQKEIESLKRRISDL--------EDEILELMERIE-ELEEELAELEAELAELEAELEEKK---AELDEELA 152
|
170
....*....|....*
gi 1390011543 999 TVKKNYEALKQRQDE 1013
Cdd:COG1579 153 ELEAELEELEAEREE 167
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
639-935 |
5.70e-04 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 44.17 E-value: 5.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 639 KENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEEN---LELRRSVESLkc 715
Cdd:pfam09728 1 KAARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKK---KQDQLQKEKDQLQSELskaILAKSKLEKL-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 716 asmrMAQLQLENKELESEKEQLRKGLELMRASFK---KTERLEVSYQGLDTENQRLQKALENSN--KKIQQL--ESELQD 788
Cdd:pfam09728 76 ----CRELQKQNKKLKEESKKLAKEEEEKRKELSekfQSTLKDIQDKMEEKSEKNNKLREENEElrEKLKSLieQYELRE 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 789 LEMENQTLQKSLE----ELKISSKRLEQlEKENKSLEQETSQLEKDK-KQLEKENKRLRQQAEIK-------DTTLEENN 856
Cdd:pfam09728 152 LHFEKLLKTKELEvqlaEAKLQQATEEE-EKKAQEKEVAKARELKAQvQTLSETEKELREQLNLYvekfeefQDTLNKSN 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1390011543 857 VKIGNLEKENKTLFKEInvykescvrlKELEKENKELVKRATIDIKTLVtlreDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:pfam09728 231 EVFTTFKKEMEKMSKKI----------KKLEKENLTWKRKWEKSNKALL----EMAEERQKLKEELEKLQKKLEKLENL 295
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
960-1170 |
5.80e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 45.04 E-value: 5.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 960 KLESTLKKSLEIKEEKIAALEARLEeSTNYNQQLrheLKTVKKNYEA---LKQRQDEERMVQSSIpvsgedDKWGRESQE 1036
Cdd:PRK10929 79 KLSAELRQQLNNERDEPRSVPPNMS-TDALEQEI---LQVSSQLLEKsrqAQQEQDRAREISDSL------SQLPQQQTE 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1037 ATRELLKVKDRL--------IEVERNNATLQAEKQALKTQLKQLETqnnnlqAQILALQRQTVS------LQEQNTTLqt 1102
Cdd:PRK10929 149 ARRQLNEIERRLqtlgtpntPLAQAQLTALQAESAALKALVDELEL------AQLSANNRQELArlrselAKKRSQQL-- 220
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 1103 qNAKLQVENSTLNSQStslmNQNAQLLIQQSSLENEN-----ESIMKEREDLKSLYDALIKDHEKLELLHERQ 1170
Cdd:PRK10929 221 -DAYLQALRNQLNSQR----QREAERALESTELLAEQsgdlpKSIVAQFKINRELSQALNQQAQRMDLIASQQ 288
|
|
| DUF3498 |
pfam12004 |
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. ... |
801-850 |
6.16e-04 |
|
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 433 to 538 amino acids in length. This domain is found associated with pfam00616, pfam00168. This domain has two conserved sequence motifs: DLQ and PLSFQNP.
Pssm-ID: 463427 [Multi-domain] Cd Length: 511 Bit Score: 44.75 E-value: 6.16e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1390011543 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQ-LEKENKRLRQQAEIKDT 850
Cdd:pfam12004 399 ERLRVSNRKLEEYERRLLAQEEQTQKLLLEYQArLEDSEERLRRQQEEKDS 449
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
706-896 |
6.30e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.38 E-value: 6.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 706 LRRSVESLKCASMR-MAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALEnsnKKIQQLES 784
Cdd:PRK12704 24 VRKKIAEAKIKEAEeEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLL---QKEENLDR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 785 ELQDLEmenqtlqksleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE-IKDTTLEE-NNVKIGNL 862
Cdd:PRK12704 101 KLELLE-----------------KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELErISGLTAEEaKEILLEKV 163
|
170 180 190
....*....|....*....|....*....|....
gi 1390011543 863 EKENKTlfkeinvykESCVRLKELEKENKELVKR 896
Cdd:PRK12704 164 EEEARH---------EAAVLIKEIEEEAKEEADK 188
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1032-1212 |
6.41e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.37 E-value: 6.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1032 RESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL--QV 1109
Cdd:COG1579 3 PEDLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYeeQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1110 ENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKhgtLKSAHK 1189
Cdd:COG1579 83 GNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAE---LEAELE 159
|
170 180 190
....*....|....*....|....*....|.
gi 1390011543 1190 NLEVEHKDLE--------DRYNQLLKQKGQL 1212
Cdd:COG1579 160 ELEAEREELAakippellALYERIRKRKNGL 190
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
566-742 |
6.86e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 44.31 E-value: 6.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 566 TVSSLRQRSQISAEARvkDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKgeraEELENELNHLGKENELLQ 645
Cdd:PRK12705 21 LVVLLKKRQRLAKEAE--RILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRER----EELQREEERLVQKEEQLD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 646 KKitnlkitCEKLETLEQENSELEREnrkfkktldsfknLTFQLESLEKENSQLDEENLElrrsVESLKCASMRMAQLQL 725
Cdd:PRK12705 95 AR-------AEKLDNLENQLEEREKA-------------LSARELELEELEKQLDNELYR----VAGLTPEQARKLLLKL 150
|
170
....*....|....*..
gi 1390011543 726 ENKELESEKEQLRKGLE 742
Cdd:PRK12705 151 LDAELEEEKAQRVKKIE 167
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
498-1010 |
7.37e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 44.43 E-value: 7.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 498 KENQRLNKKVEILENEIIQEKQSLQ-------------NCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN 564
Cdd:pfam10174 130 KELFLLRKTLEEMELRIETQKQTLGardesikkllemlQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENI 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 565 QTVSSLRQRSQISAEArvkdieKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGE-RAEELENEL--------- 634
Cdd:pfam10174 210 HLREELHRRNQLQPDP------AKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLlHTEDREEEIkqmevyksh 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 635 -----NHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLES--------LEKENSQLDE 701
Cdd:pfam10174 284 skfmkNKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTevdalrlrLEEKESFLNK 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 702 ENLELRRSVESLKCASMRMAQLQ--LENKE---------LESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQK 770
Cdd:pfam10174 364 KTKQLQDLTEEKSTLAGEIRDLKdmLDVKErkinvlqkkIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEE 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 771 ALENSNKKIQQL----ESELQDLEMENQTLQKSLEELK--ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKrlRQQ 844
Cdd:pfam10174 444 ALSEKERIIERLkeqrEREDRERLEELESLKKENKDLKekVSALQPELTEKESSLIDLKEHASSLASSGLKKDSK--LKS 521
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 845 AEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKE---NKELVKRATIDIKTLVTLREDLVSEKlktqqm 921
Cdd:pfam10174 522 LEIAVEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEvarYKEESGKAQAEVERLLGILREVENEK------ 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 922 nNDLEKLTHELEKIGLNKerllHDEQSTDDSRYKLLESKLEstlKKSLEIKEEKIAALEARLEESTNYN-QQLRHELKTV 1000
Cdd:pfam10174 596 -NDKDKKIAELESLTLRQ----MKEQNKKVANIKHGQQEMK---KKGAQLLEEARRREDNLADNSQQLQlEELMGALEKT 667
|
570
....*....|
gi 1390011543 1001 KKNYEALKQR 1010
Cdd:pfam10174 668 RQELDATKAR 677
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
1037-1353 |
7.46e-04 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 43.90 E-value: 7.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1037 ATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQletqnnnLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNS 1116
Cdd:pfam15742 32 AEKELRYERGKNLDLKQHNSLLQEENIKIKAELKQ-------AQQKLLDSTKMCSSLTAEWKHCQQKIRELELEVLKQAQ 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1117 QSTSLMNQNAQLLIQQSSLENENESIMKEREDLKS-----LYDALIKDHEKLElLHERQASEYESliskhgTLKSAHKNL 1191
Cdd:pfam15742 105 SIKSQNSLQEKLAQEKSRVADAEEKILELQQKLEHahkvcLTDTCILEKKQLE-ERIKEASENEA------KLKQQYQEE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1192 EVEHKDLEDRYNQLLKQKGQLEDLEKMIK----------TEQEKMLLESKNHEVVASEYKKLCGEndrLNYTYSQLLKET 1261
Cdd:pfam15742 178 QQKRKLLDQNVNELQQQVRSLQDKEAQLEmtnsqqqlriQQQEAQLKQLENEKRKSDEHLKSNQE---LSEKLSSLQQEK 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1262 EILQMDHKNLKSVLN----NSKLEQTRLEAEFSKLKEQY----QQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQT 1333
Cdd:pfam15742 255 EALQEELQQVLKQLDvhvrKYNEKHHHHKAKLRRAKDRLvhevEQRDERIKQLENEIGILQQQSEKEKAFQKQVTAQNEI 334
|
330 340
....*....|....*....|
gi 1390011543 1334 LMLQNRTLLEQNMESKDLFH 1353
Cdd:pfam15742 335 LLLEKRKLLEQLTEQEELIK 354
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
657-846 |
7.54e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.37 E-value: 7.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 657 KLETLEQENSELERENRKFKKTLDSFKNltfQLESLEKENSQLDEENLELRRSVeslkcasmrmaqlqlenKELESEKEQ 736
Cdd:COG1579 11 DLQELDSELDRLEHRLKELPAELAELED---ELAALEARLEAAKTELEDLEKEI-----------------KRLELEIEE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 737 LRKGLElmrasfKKTERLEvsyQGLDT-ENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKisskrlEQLEK 815
Cdd:COG1579 71 VEARIK------KYEEQLG---NVRNNkEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELE------AELAE 135
|
170 180 190
....*....|....*....|....*....|.
gi 1390011543 816 ENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG1579 136 LEAELEEKKAELDEELAELEAELEELEAERE 166
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
491-648 |
8.04e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.99 E-value: 8.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 491 SKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN------------SERQIKILEQ 558
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARikkyeeqlgnvrNNKEYEALQK 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 559 ENEHLnqtvsslrQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELElykekgERAEELENELNHLG 638
Cdd:COG1579 97 EIESL--------KRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELD------EELAELEAELEELE 162
|
170
....*....|
gi 1390011543 639 KENELLQKKI 648
Cdd:COG1579 163 AEREELAAKI 172
|
|
| Prefoldin_2 |
pfam01920 |
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996. |
777-854 |
9.06e-04 |
|
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996.
Pssm-ID: 396482 [Multi-domain] Cd Length: 102 Bit Score: 40.28 E-value: 9.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 777 KKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENK------------SLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam01920 2 NKFQQLQQQLQLLAQQIKQLETQLKELELALEELELLDEDTKvykligdvlvkqDKEEVKEQLEERKETLEKEIKTLEKQ 81
|
90
....*....|
gi 1390011543 845 AEIKDTTLEE 854
Cdd:pfam01920 82 LEKLEKELEE 91
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
252-351 |
1.00e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 44.08 E-value: 1.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnllsdARSARMYRDELDALREkavRVDKLESELSR 331
Cdd:COG2433 414 EIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE-------ERREIRKDREISRLDR---EIERLERELEE 483
|
90 100
....*....|....*....|
gi 1390011543 332 YKERLHDIefyKARVEELKE 351
Cdd:COG2433 484 ERERIEEL---KRKLERLKE 500
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
537-698 |
1.02e-03 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 43.91 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEK----ENKILHESIKETCGKLSKIEFEKRQ 612
Cdd:COG5244 116 RLEETIEALKSTEKEEIVELRRENEELDKINLSLRERISSEEPELNKDGSKlsydELKEFVEESRVQVYDMVELVSDISE 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 613 MKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLE----TLEQENSELERENRKFKKTLDSFKNLTFQ 688
Cdd:COG5244 196 TLNRNGSIQRSSVRECERSNIHDVLFLVNGILDGVIDELNGELERLRrqlvSLMSSHGIEVEENSRLKATLEKFQSLELK 275
|
170
....*....|
gi 1390011543 689 LESLEKENSQ 698
Cdd:COG5244 276 VNTLQEELYQ 285
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
678-894 |
1.02e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 44.13 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLEN---KELESEKEQLRKGLELMRASFKKTERL 754
Cdd:PRK11281 71 LLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTlslRQLESRLAQTLDQLQNAQNDLAEYNSQ 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 755 EVSYQgldTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSleelkisskRLEQLEKENKSLEQETSQlekdKKQL 834
Cdd:PRK11281 151 LVSLQ---TQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPS---------QRVLLQAEQALLNAQNDL----QRKS 214
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 835 EKENKRLRQQAEIKdttLEENNVKIGNLEKENKTLFKEINVYkescvRLKELEKENKELV 894
Cdd:PRK11281 215 LEGNTQLQDLLQKQ---RDYLTARIQRLEHQLQLLQEAINSK-----RLTLSEKTVQEAQ 266
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
682-1377 |
1.03e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.06 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 682 FKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGL 761
Cdd:pfam12128 236 IMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADA 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 762 DTENQRLQ-KALENSNKKIQQ--LESELQDLEMENQtLQKSLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQ----- 833
Cdd:pfam12128 316 AVAKDRSElEALEDQHGAFLDadIETAAADQEQLPS-WQSELENL---EERLKALTGKHQDVTAKYNRRRSKIKEqnnrd 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 834 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKE-NKTLFKEINVYKESCVRLKELEKENKELVKRATIdiktlvtlredlv 912
Cdd:pfam12128 392 IAGIKDKLAKIREARDRQLAVAEDDLQALESElREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATA------------- 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 913 SEKLKTQQMNND--LEKLTHELEKIGLNKERLLHDEqstddsryklleskleSTLKKSLEIKEEKIAALEARLEESTNYN 990
Cdd:pfam12128 459 TPELLLQLENFDerIERAREEQEAANAEVERLQSEL----------------RQARKRRDQASEALRQASRRLEERQSAL 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 991 QQLRHELKTVKKNYEALKQRQdeermvqssipVSGEDDKWGREsqeATRELLKVKDRLIEVERNNATLQAEKQALKTQLK 1070
Cdd:pfam12128 523 DELELQLFPQAGTLLHFLRKE-----------APDWEQSIGKV---ISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLK 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1071 QLETQNNNLQAQILALQRQTVSlqeqnTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLK 1150
Cdd:pfam12128 589 RIDVPEWAASEEELRERLDKAE-----EALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQ 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1151 SLYDALIK----------------DHEKLELLHERQA--SEYESLISKHGTLKSAH-KNLEVEHKDLEDRYNQLL----- 1206
Cdd:pfam12128 664 SEKDKKNKalaerkdsanerlnslEAQLKQLDKKHQAwlEEQKEQKREARTEKQAYwQVVEGALDAQLALLKAAIaarrs 743
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1207 KQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKL------CGENDRLNYTYSQLLKETEILQMDhkNLKSVLNNSKL 1280
Cdd:pfam12128 744 GAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLerkierIAVRRQEVLRYFDWYQETWLQRRP--RLATQLSNIER 821
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1281 EQTRLEAEFSKLKEqyqqlditSTKLNNQcELLSQLKGN------LEEENRHLLDQIQTLmlqNRTLLEQNMESKDLfhv 1354
Cdd:pfam12128 822 AISELQQQLARLIA--------DTKLRRA-KLEMERKASekqqvrLSENLRGLRCEMSKL---ATLKEDANSEQAQG--- 886
|
730 740
....*....|....*....|...
gi 1390011543 1355 EQRQYIDKLNELRRQKEKLEEKI 1377
Cdd:pfam12128 887 SIGERLAQLEDLKLKRDYLSESV 909
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
992-1201 |
1.17e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.14 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 992 QLRHELKTVKKNYEALKQ-RQDEERMVQSSIPVSG-EDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQL 1069
Cdd:COG4913 239 RAHEALEDAREQIELLEPiRELAERYAAARERLAElEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARL 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1070 KQLETQNNNLQAQILALQRQTVslqeqnTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLliqqssleneNESIMKEREDL 1149
Cdd:COG4913 319 DALREELDELEAQIRGNGGDRL------EQLEREIERLERELEERERRRARLEALLAAL----------GLPLPASAEEF 382
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 1390011543 1150 KSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDR 1201
Cdd:COG4913 383 AALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERR 434
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
305-512 |
1.18e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 305 ARMYRDELDALREKAVR--VDKLESELSRYKERLHDIEfykARVEELKEDNQVLL--ETKTMLEDQLEGTRARsdkLHEL 380
Cdd:COG3206 158 AEAYLEQNLELRREEARkaLEFLEEQLPELRKELEEAE---AALEEFRQKNGLVDlsEEAKLLLQQLSELESQ---LAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 381 EKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQISRT-----SELAEAPQK--SLGHE 453
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEA-----ELAELSARytpnhPDVIALRAQiaALRAQ 306
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1390011543 454 VNELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILEN 512
Cdd:COG3206 307 LQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
453-590 |
1.28e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 43.61 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 453 EVNELTSSKLLKLEMENQSLTKTVE-ELRStadsaagstsKILKVEKENQRLNKKVEILENE---IIQEKQSLQNCQnls 528
Cdd:PRK12704 50 EAEAIKKEALLEAKEEIHKLRNEFEkELRE----------RRNELQKLEKRLLQKEENLDRKlelLEKREEELEKKE--- 116
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 529 KDLMKEKAQLEKTIETLRENSERQIKILEQ-----ENEHLNQTVSSLRQRSQISAEARVKDIEKENK 590
Cdd:PRK12704 117 KELEQKQQELEKKEEELEELIEEQLQELERisgltAEEAKEILLEKVEEEARHEAAVLIKEIEEEAK 183
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
792-843 |
1.31e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 43.28 E-value: 1.31e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1390011543 792 ENQTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Cdd:PRK03992 2 RLEALEERNSELE---EQIRQLELKLRDLEAENEKLERELERLKSELEKLKS 50
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
808-1204 |
1.54e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 43.41 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKtlfKEINVYKESCVRLKELE 887
Cdd:COG5185 166 GKLTQELNQNLKKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKA---KEIINIEEALKGFQDPE 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 888 KENkELVKRATIDIKTLVTLREDLVSEKL-----KTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDSRyklleskle 962
Cdd:COG5185 243 SEL-EDLAQTSDKLEKLVEQNTDLRLEKLgenaeSSKRLNENANNLIKQFENT---KEKIAEYTKSIDIKK--------- 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 963 STLKKSLEIKE-EKIAALEARLEESTNYNQQLRHELKtvkKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATREL 1041
Cdd:COG5185 310 ATESLEEQLAAaEAEQELEESKRETETGIQNLTAEIE---QGQESLTENLEAIKEEIENIVGEVELSKSSEELDSFKDTI 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1042 LKVKDRLIEVERNNATLQAE-KQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQnaklQVENSTLNSQSTS 1120
Cdd:COG5185 387 ESTKESLDEIPQNQRGYAQEiLATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISE----LNKVMREADEESQ 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1121 LMNQNAQLLIQQSSLENENEsIMKEREDLKSLYDALIKDHEKLELLHERQaseYESLISKHGTLKSAHKNLEVEHKDLED 1200
Cdd:COG5185 463 SRLEEAYDEINRSVRSKKED-LNEELTQIESRVSTLKATLEKLRAKLERQ---LEGVRSKLDQVAESLKDFMRARGYAHI 538
|
....
gi 1390011543 1201 RYNQ 1204
Cdd:COG5185 539 LALE 542
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
183-345 |
1.72e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 42.83 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 183 QEDIEPLLKNMVSHLRRLIDERDEHSETIVEL--SEERDGVHFLPHASSSAQSPCGSPGMKR-TESRQHLSVELADAKAK 259
Cdd:COG4942 82 EAELAELEKEIAELRAELEAQKEELAELLRALyrLGRQPPLALLLSPEDFLDAVRRLQYLKYlAPARREQAEELRADLAE 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 260 IRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARM-YRDELDALREKAVR----VDKLESELSRYKE 334
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAeLAAELAELQQEAEElealIARLEAEAAAAAE 241
|
170
....*....|.
gi 1390011543 335 RLHDIEFYKAR 345
Cdd:COG4942 242 RTPAAGFAALK 252
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
664-832 |
1.89e-03 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 43.46 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 664 ENSELERENRKFKKTLDSFKNLTFQLESLEKENSQL-----DEENLELRRSVESLKCASMRMAQLQLENKElESEKEQLR 738
Cdd:PTZ00419 826 NNEALDEEMKIIMSIVKSIRSLIATLGIPNKTKPDCyvtakDAELIELIESAENLISTLAKIGSVSVIPPI-EEEAEVPK 904
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 739 K-GLELMRASFKKTERLEVSYQgLDTENQRLQKALENSNKKIQQLESELQDLEMEnqtlQKSLEELK-ISSKRLEQLEKE 816
Cdd:PTZ00419 905 GcGFDVVDNKVIIYLNLDEFID-LKKELAKLEKKLAKLQKSLESYLKKISIPNYE----DKVPEDVRkLNDEKIDELNEE 979
|
170
....*....|....*.
gi 1390011543 817 NKSLEQETSQLEKDKK 832
Cdd:PTZ00419 980 IKQLEQAIEELKSLLK 995
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
240-573 |
2.03e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.40 E-value: 2.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 240 MKRTESRQHLSVELADAkakirrlRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSArmyRDELdALREKA 319
Cdd:COG3096 274 MRHANERRELSERALEL-------RRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAA---SDHL-NLVQTA 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 320 VRvdkLESELSRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERD 399
Cdd:COG3096 343 LR---QQEKIERYQEDLEELT------ERLEEQEEVVEE----AAEQLAEAEAR---LEAAEEEVDSLKSQLADYQQALD 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 400 MDRKKIEELMEENMTLEMAQKQSMDESLHlgweLEQISRTSELAEAPQKSLGHEVNELtSSKLLKLEMENQSLTKTVEEL 479
Cdd:COG3096 407 VQQTRAIQYQQAVQALEKARALCGLPDLT----PENAEDYLAAFRAKEQQATEEVLEL-EQKLSVADAARRQFEKAYELV 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 480 RSTAD----SAAGSTSK-ILKVEKENQRLNKKVEILE---NEIIQEKQSLQNCQNLSKDLMK--------------EKAQ 537
Cdd:COG3096 482 CKIAGeverSQAWQTAReLLRRYRSQQALAQRLQQLRaqlAELEQRLRQQQNAERLLEEFCQrigqqldaaeeleeLLAE 561
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1390011543 538 LEKTIETL----RENSERQIKiLEQENEHLNQTVSSLRQR 573
Cdd:COG3096 562 LEAQLEELeeqaAEAVEQRSE-LRQQLEQLRARIKELAAR 600
|
|
| ATG14 |
pfam10186 |
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are ... |
715-851 |
2.04e-03 |
|
Vacuolar sorting 38 and autophagy-related subunit 14; The Atg14 or Apg14 proteins are hydrophilic proteins with a predicted molecular mass of 40.5 kDa, and have a coiled-coil motif at the N terminus region. Yeast cells with mutant Atg14 are defective not only in autophagy but also in sorting of carboxypeptidase Y (CPY), a vacuolar-soluble hydrolase, to the vacuole. Subcellular fractionation indicate that Apg14p and Apg6p are peripherally associated with a membrane structure(s). Apg14p was co-immunoprecipitated with Apg6p, suggesting that they form a stable protein complex. These results imply that Apg6/Vps30p has two distinct functions: in the autophagic process and in the vacuolar protein sorting pathway. Apg14p may be a component specifically required for the function of Apg6/Vps30p through the autophagic pathway. There are 17 auto-phagosomal component proteins which are categorized into six functional units, one of which is the AS-PI3K complex (Vps30/Atg6 and Atg14). The AS-PI3K complex and the Atg2-Atg18 complex are essential for nucleation, and the specific function of the AS-PI3K apparently is to produce phosphatidylinositol 3-phosphate (PtdIns(3)P) at the pre-autophagosomal structure (PAS). The localization of this complex at the PAS is controlled by Atg14. Autophagy mediates the cellular response to nutrient deprivation, protein aggregation, and pathogen invasion in humans, and malfunction of autophagy has been implicated in multiple human diseases including cancer. This effect seems to be mediated through direct interaction of the human Atg14 with Beclin 1 in the human phosphatidylinositol 3-kinase class III complex.
Pssm-ID: 462986 [Multi-domain] Cd Length: 347 Bit Score: 42.44 E-value: 2.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 715 CASMRMAQLQLENKELESEKEQLRKglelmrasfKKTERLEvsyqgLDTENQRLQKALENSNKKIQQLESELQDLEMENQ 794
Cdd:pfam10186 16 CARNRLYELRVDLARLLSEKDSLKK---------KVEEALE-----GKEEGEQLEDNIGNKKLKLRLLKSEVAISNERLN 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1390011543 795 TLQKSLEELK--ISSKRlEQLEKENKSLEQETSQLEKDKKQLekENKRLRQQAEIKDTT 851
Cdd:pfam10186 82 EIKDKLDQLRreIAEKK-KKIEKLRSSLKQRRSDLESASYQL--EERRASQLAKLQNSI 137
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
602-910 |
2.06e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 43.09 E-value: 2.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 602 KLSKIEFEKRQMKKELELyKEKGERAEELENELNHLGKENELLQkkiTNLKITCEKLETLEQENSELERENRKFKKTLDS 681
Cdd:pfam05667 320 PTKVETEEELQQQREEEL-EELQEQLEDLESSIQELEKEIKKLE---SSIKQVEEELEELKEQNEELEKQYKVKKKTLDL 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 682 FKNltfqleslekensqlDEENL-ELRRSVESlkcASMRMAQLQlenKELESEKEQLRKglelmrasfkkterlevsyqg 760
Cdd:pfam05667 396 LPD---------------AEENIaKLQALVDA---SAQRLVELA---GQWEKHRVPLIE--------------------- 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 761 ldtENQRLQKALENSNKKIQQLESELQDLEmenQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR 840
Cdd:pfam05667 434 ---EYRALKEAKSNKEDESQRKLEEIKELR---EKIKEVAEEAKQKEELYKQLVAEYERLPKDVSRSAYTRRILEIVKNI 507
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 841 LRQQAEIkdttleennVKIgnLEkENKTLFKEINVYKESCVR----LKEL-EKENK--ELVKRAtidIKTLVTLRED 910
Cdd:pfam05667 508 KKQKEEI---------TKI--LS-DTKSLQKEINSLTGKLDRtftvTDELvFKDAKkdESVRKA---YKYLAALHEN 569
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1135-1357 |
2.55e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.57 E-value: 2.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1135 LENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKG---- 1210
Cdd:pfam07888 50 QEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAahea 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1211 QLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGendrlnytysqLLKETEilqMDHKNLKSVLNNSKLEQTRLEAEFS 1290
Cdd:pfam07888 130 RIRELEEDIKTLTQRVLERETELERMKERAKKAGA-----------QRKEEE---AERKQLQAKLQQTEEELRSLSKEFQ 195
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 1291 KLKEQYQQLDITSTKLNNQCELLSQlkgnleeenrhLLDQIQTLMLQNRTLLEQNMESKDLFHVEQR 1357
Cdd:pfam07888 196 ELRNSLAQRDTQVLQLQDTITTLTQ-----------KLTTAHRKEAENEALLEELRSLQERLNASER 251
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
945-1110 |
2.66e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 2.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 945 DEQSTDDSRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTN---------YNQQLRHELKTVKKNYEALKQRQDEE- 1014
Cdd:COG3206 212 EEAKLLLQQLSELESQL-AEARAELAEAEARLAALRAQLGSGPDalpellqspVIQQLRAQLAELEAELAELSARYTPNh 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1015 -RMVQSsipvsgeddkwgRESQEATRELLK--VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL---QAQILALQR 1088
Cdd:COG3206 291 pDVIAL------------RAQIAALRAQLQqeAQRILASLEAELEALQAREASLQAQLAQLEARLAELpelEAELRRLER 358
|
170 180
....*....|....*....|..
gi 1390011543 1089 QTVSLQEQNTTLQTQNAKLQVE 1110
Cdd:COG3206 359 EVEVARELYESLLQRLEEARLA 380
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
776-1202 |
2.69e-03 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 42.37 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 776 NKKIQQLESELQDLEMENQTLQKSLEELK-------ISSKRLEQLEKENKSLEQETSQLEKDKKQLekenkrlRQQAEIK 848
Cdd:pfam05622 20 DQQVSLLQEEKNSLQQENKKLQERLDQLEsgddsgtPGGKKYLLLQKQLEQLQEENFRLETARDDY-------RIKCEEL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 849 DTTLEENNVKIGNLEK---ENKTLFKEINVYKESCVRLKELEkenkelvkrATIDiktlvtlredlvSEKLKTQQMNnDL 925
Cdd:pfam05622 93 EKEVLELQHRNEELTSlaeEAQALKDEMDILRESSDKVKKLE---------ATVE------------TYKKKLEDLG-DL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 926 EKLTHELEkiglnkERLLHDEQSTDDSRYkllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYE 1005
Cdd:pfam05622 151 RRQVKLLE------ERNAEYMQRTLQLEE---ELKKANALRGQLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKLE 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1006 AL---KQRQDEER--------------MVQSSIPVSGEDDKWGRESQE-ATRELL--KVKDRLIEVERNNATL------- 1058
Cdd:pfam05622 222 ALqkeKERLIIERdtlretneelrcaqLQQAELSQADALLSPSSDPGDnLAAEIMpaEIREKLIRLQHENKMLrlgqegs 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1059 ----QAEKQALKTQ----LKQLETQNNNLQAQILALQRQTVSLQeqnTTLQTQNAKlqvenstlnSQSTSLMNQnaQLLI 1130
Cdd:pfam05622 302 yrerLTELQQLLEDanrrKNELETQNRLANQRILELQQQVEELQ---KALQEQGSK---------AEDSSLLKQ--KLEE 367
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1390011543 1131 QQSSLENENESIMKeredlkslydalikdheKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRY 1202
Cdd:pfam05622 368 HLEKLHEAQSELQK-----------------KKEQIEELEPKQDSNLAQKIDELQEALRKKDEDMKAMEERY 422
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
728-844 |
2.94e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 41.05 E-value: 2.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 728 KELESEKEQLRKGLELMRASFKKTERlevsyqgldtENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSleelkisS 807
Cdd:pfam13851 29 KSLKEEIAELKKKEERNEKLMSEIQQ----------ENKRLTEPLQKAQEEVEELRKQLENYEKDKQSLKNL-------K 91
|
90 100 110
....*....|....*....|....*....|....*..
gi 1390011543 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam13851 92 ARLKVLEKELKDLKWEHEVLEQRFEKVERERDELYDK 128
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
761-916 |
2.94e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 42.74 E-value: 2.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 761 LDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKE--- 837
Cdd:pfam05911 672 VSGSNDLKTEENKRLKEEFEQLKSEKENLEVELASCTENLESTKS---QLQESEQLIAELRSELASLKESNSLAETQlkc 748
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 838 ----NKRLRQQAEIKDTTLEENNVKIGNLEKEnktLFKEINVYKESCVRLKELE-----KENKELVKRATIDIKTLVTLR 908
Cdd:pfam05911 749 maesYEDLETRLTELEAELNELRQKFEALEVE---LEEEKNCHEELEAKCLELQeqlerNEKKESSNCDADQEDKKLQQE 825
|
170
....*....|
gi 1390011543 909 EDLV--SEKL 916
Cdd:pfam05911 826 KEITaaSEKL 835
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
239-565 |
2.97e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 42.63 E-value: 2.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 239 GMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQEnmnlLSDarsarmYRDELDALREK 318
Cdd:COG3096 342 ALRQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQ----LAD------YQQALDVQQTR 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 319 AVRVDKLESELSRYKERLH----DIEFYKARVEELKEDNQVLLETKTMLEDQLegtrARSDKLHELEKENLQLKAKLHDm 394
Cdd:COG3096 412 AIQYQQAVQALEKARALCGlpdlTPENAEDYLAAFRAKEQQATEEVLELEQKL----SVADAARRQFEKAYELVCKIAG- 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 395 EMERDMDRKKIEELMEENMTLEM--AQKQSMDESLHlgwELEQISRTSELAEAPQKSLGHEVNELTSSKLLkLEMENQSL 472
Cdd:COG3096 487 EVERSQAWQTARELLRRYRSQQAlaQRLQQLRAQLA---ELEQRLRQQQNAERLLEEFCQRIGQQLDAAEE-LEELLAEL 562
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 473 TKTVEELrstADSAAGSTSKILKVEKENQRLNKKVEILEN------------EIIQEK--QSLQNCQNLSkDLMKEKAQL 538
Cdd:COG3096 563 EAQLEEL---EEQAAEAVEQRSELRQQLEQLRARIKELAArapawlaaqdalERLREQsgEALADSQEVT-AAMQQLLER 638
|
330 340
....*....|....*....|....*..
gi 1390011543 539 EKTIETLRENSERQIKILEQENEHLNQ 565
Cdd:COG3096 639 EREATVERDELAARKQALESQIERLSQ 665
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
474-846 |
3.53e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 3.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 474 KTVEELRSTADSAAGSTSKILKVEKENQRLN-----KKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE- 547
Cdd:COG4913 252 ELLEPIRELAERYAAARERLAELEYLRAALRlwfaqRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAq 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 548 ---NSERQIKILEQENEHLNQTVSSLRQRSQI------SAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELE 618
Cdd:COG4913 332 irgNGGDRLEQLEREIERLERELEERERRRARleallaALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAE 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 619 -LYKEKGERAEELENELNHL--GKEN-------------ELLQKKITNLKITCEKLETLEQENS---ELER--------- 670
Cdd:COG4913 412 aALRDLRRELRELEAEIASLerRKSNiparllalrdalaEALGLDEAELPFVGELIEVRPEEERwrgAIERvlggfaltl 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 671 --------------ENRKFKKTLDSFKnltFQLESLEKENSQLDEENL-----------------ELRR--------SVE 711
Cdd:COG4913 492 lvppehyaaalrwvNRLHLRGRLVYER---VRTGLPDPERPRLDPDSLagkldfkphpfrawleaELGRrfdyvcvdSPE 568
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 712 SLKCASMRM-----------------------------------AQLQLENKELESEKEQLRKGLELMRASFKKTERLEV 756
Cdd:COG4913 569 ELRRHPRAItragqvkgngtrhekddrrrirsryvlgfdnraklAALEAELAELEEELAEAEERLEALEAELDALQERRE 648
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 757 SYQGLDtENQRLQKALENSNKKIQQLESELQDLEMEN---QTLQKSLEELKissKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:COG4913 649 ALQRLA-EYSWDEIDVASAEREIAELEAELERLDASSddlAALEEQLEELE---AELEELEEELDELKGEIGRLEKELEQ 724
|
490
....*....|...
gi 1390011543 834 LEKENKRLRQQAE 846
Cdd:COG4913 725 AEEELDELQDRLE 737
|
|
| Atg16_CCD |
cd22887 |
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family ... |
1045-1114 |
3.54e-03 |
|
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family includes Saccharomyces cerevisiae Atg16 (also called cytoplasm to vacuole targeting protein 11, CVT11, or SAP18), human autophagy-related protein 16-1 (also called APG16-like 1, ATG16L1, or APG16L) and autophagy-related protein 16-2 (also called APG16-like 2, ATG16L2, WD repeat-containing protein 80 or WDR80), and similar proteins. Atg16 stabilizes the Atg5-Atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The Atg5-Atg12/Atg16 complex is required for efficient promotion of Atg8-conjugation to phosphatidylethanolamine and Atg8 localization to the pre-autophagosomal structure (PAS). Similarly, human ATG16L1 plays an essential role in autophagy and acts as a molecular scaffold which mediates protein-protein interactions essential for autophagosome formation. ATG16L2, though structurally similar to ATG16L1 and able to form a complex with the autophagy proteins Atg5 and Atg12, is not essential for autophagy. Single-nucleotide polymorphisms in ATG16L1 is associated with an increased risk of developing Crohn disease. Saccharomyces cerevisiae Atg16 contains an N-terminal domain (NTD) that interacts with the Atg5-Atg12 protein conjugate and a coiled-coil domain (CCD) that dimerizes and mediates self-assembly. Human ATG16L1 and ATG16L2 also contains an N-terminal region that binds Atg5, a CCD homologous to the yeast CCD, and a WD40 domain that represents approximately 50% of the full-length protein. This model corresponds to the CCD of Atg16 family proteins.
Pssm-ID: 439196 [Multi-domain] Cd Length: 91 Bit Score: 38.32 E-value: 3.54e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1045 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Cdd:cd22887 3 ESELQELEKRLAELEAELASLEEEIKDLEEELKEKNKANEILNDELIALQIENNLLEEKLRKLQEENDEL 72
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
705-1115 |
3.58e-03 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 42.43 E-value: 3.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 705 ELRRSVESLKcaSMRMAQLQlENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLES 784
Cdd:pfam07111 74 ELRRLEEEVR--LLRETSLQ-QKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGSQRELEEIQRLHQ 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 785 ElqDLEMENQTLQKSLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEk 864
Cdd:pfam07111 151 E--QLSSLTQAHEEALSSL---TSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLVESLR- 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 865 enktlfKEINVYKESCVRLKELEKENKELvkratidIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELekiGLNKERLLH 944
Cdd:pfam07111 225 ------KYVGEQVPPEVHSQTWELERQEL-------LDTMQHLQEDRADLQATVELLQVRVQSLTHML---ALQEEELTR 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 945 DEQSTDdsrykLLESKLESTLKKSLEIKEEKIAALEARLEEstnynQQLRHElktvkknyEALKQRQDEERMVQSSIPVS 1024
Cdd:pfam07111 289 KIQPSD-----SLEPEFPKKCRSLLNRWREKVFALMVQLKA-----QDLEHR--------DSVKQLRGQVAELQEQVTSQ 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1025 GEDdkwgresQEATRELLKVKDRLIEVERNNA-TLQAE----KQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTT 1099
Cdd:pfam07111 351 SQE-------QAILQRALQDKAAEVEVERMSAkGLQMElsraQEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTR 423
|
410
....*....|....*.
gi 1390011543 1100 LQTQNAKLQVENSTLN 1115
Cdd:pfam07111 424 VEQAVARIPSLSNRLS 439
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
596-826 |
3.72e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 41.74 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 596 IKETCGKLSKIEFEKRQMKKELelyKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLET-LEQENSELERENRK 674
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAEL---DALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAeIEERREELGERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 675 FKKTLDSFKNLTFQLESlekensqldeENLE--LRRsVESLKCASMRMAQLQLENKELESEKEQLRKGLElmrasfKKTE 752
Cdd:COG3883 95 LYRSGGSVSYLDVLLGS----------ESFSdfLDR-LSALSKIADADADLLEELKADKAELEAKKAELE------AKLA 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1390011543 753 RLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:COG3883 158 ELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
251-673 |
3.99e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 42.06 E-value: 3.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 251 VELADAKAKIRRLRQELEEKTEQLLDCKQELEQI---EVELKRLQQENMNLLSDARSARMYRDE--LDALREKAVRVDKL 325
Cdd:COG4717 125 LQLLPLYQELEALEAELAELPERLEELEERLEELrelEEELEELEAELAELQEELEELLEQLSLatEEELQDLAEELEEL 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 326 ESELSRYKERLHDIEfykARVEELKEDnqvlletktmlEDQLEGTRARSDKLHELEKENLQLK--AKLHDMEMERDMDRK 403
Cdd:COG4717 205 QQRLAELEEELEEAQ---EELEELEEE-----------LEQLENELEAAALEERLKEARLLLLiaAALLALLGLGGSLLS 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 404 KIEELMEenMTLEMAQkqsmdeSLHLGWELEQISRTSELAEAPQKSLGHEVNELtsskllklemENQSLTKTVEELRSTA 483
Cdd:COG4717 271 LILTIAG--VLFLVLG------LLALLFLLLAREKASLGKEAEELQALPALEEL----------EEEELEELLAALGLPP 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 484 DSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIE---TLRENSERQIKILEQEN 560
Cdd:COG4717 333 DLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEqaeEYQELKEELEELEEQLE 412
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 561 EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMkkelelykEKGERAEELENELNHLGKE 640
Cdd:COG4717 413 ELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL--------EEDGELAELLQELEELKAE 484
|
410 420 430
....*....|....*....|....*....|...
gi 1390011543 641 NELLQKKITNLKITcekLETLEQENSELERENR 673
Cdd:COG4717 485 LRELAEEWAALKLA---LELLEEAREEYREERL 514
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
683-852 |
4.19e-03 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 40.27 E-value: 4.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 683 KNLTFQLESLEKENSQLDEENL-----------ELRRSVESLKCASMRMAQLqleNKELESEKEQLRKGLELMRASFKKT 751
Cdd:pfam15619 14 KELQNELAELQSKLEELRKENRllkrlqkrqekALGKYEGTESELPQLIARH---NEEVRVLRERLRRLQEKERDLERKL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 752 ERLEVSYQGLDTENQRLQKALENSN--------KKIQQLESELQDLEMENQTLQKSLEELKISSKRleQLEKENKSleqe 823
Cdd:pfam15619 91 KEKEAELLRLRDQLKRLEKLSEDKNlaereelqKKLEQLEAKLEDKDEKIQDLERKLELENKSFRR--QLAAEKKK---- 164
|
170 180
....*....|....*....|....*....
gi 1390011543 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Cdd:pfam15619 165 HKEAQEEVKILQEEIERLQQKLKEKEREL 193
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
784-820 |
4.63e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 41.12 E-value: 4.63e-03
10 20 30
....*....|....*....|....*....|....*..
gi 1390011543 784 SELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSL 820
Cdd:PRK13922 69 ASLFDLREENEELKKELLELESRLQELEQLEAENARL 105
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
505-769 |
4.75e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 41.84 E-value: 4.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 505 KKVEIL-ENEIIqeKQSLQNCQNLSK---DLMKEKAQLEKtietLRENSERQIKI------LEQENEHLNQTVSSLRQRS 574
Cdd:PRK05771 7 KKVLIVtLKSYK--DEVLEALHELGVvhiEDLKEELSNER----LRKLRSLLTKLsealdkLRSYLPKLNPLREEKKKVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 575 QISAEARVKDIEKE-NKILhESIKETCGKLSKIEFEKRQMKKELelykekgERAEELENelnhLGKENELLQKKiTNLKI 653
Cdd:PRK05771 81 VKSLEELIKDVEEElEKIE-KEIKELEEEISELENEIKELEQEI-------ERLEPWGN----FDLDLSLLLGF-KYVSV 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 654 TC-----EKLETLEQENSELERENRKFKKTLD--SFKNLTFQLESLEKENSQLDEENLELRRSVEslkcASMRMAQLQLE 726
Cdd:PRK05771 148 FVgtvpeDKLEELKLESDVENVEYISTDKGYVyvVVVVLKELSDEVEEELKKLGFERLELEEEGT----PSELIREIKEE 223
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1390011543 727 NKELESEKEQLRKGLElmrASFKKTERLEVSYQG-LDTENQRLQ 769
Cdd:PRK05771 224 LEEIEKERESLLEELK---ELAKKYLEELLALYEyLEIELERAE 264
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1196-1377 |
5.02e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.68 E-value: 5.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1196 KDLEDRYNQLLKQKG--------QLEDLEKMIKTEQEKMllesknhevvaSEYKKLCGENDRLNYTYSQLLKETEILQMD 1267
Cdd:COG4717 49 ERLEKEADELFKPQGrkpelnlkELKELEEELKEAEEKE-----------EEYAELQEELEELEEELEELEAELEELREE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1268 HKNLKSVLNNSKLEQTR--LEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQN 1345
Cdd:COG4717 118 LEKLEKLLQLLPLYQELeaLEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDL 197
|
170 180 190
....*....|....*....|....*....|..
gi 1390011543 1346 MESKDLFHVEQRQYIDKLNELRRQKEKLEEKI 1377
Cdd:COG4717 198 AEELEELQQRLAELEEELEEAQEELEELEEEL 229
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
319-549 |
5.07e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 5.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 319 AVRVDKLESELSRYKERlhdIEFYKARVEELKEDNQVLLETKTMLEDQLEgtrARSDKLHELEKENLQLKAKLHDMEMER 398
Cdd:COG4942 19 ADAAAEAEAELEQLQQE---IAELEKELAALKKEEKALLKQLAALERRIA---ALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 399 DMDRKKIEELMEE----NMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSsKLLKLEMENQSLTK 474
Cdd:COG4942 93 AELRAELEAQKEElaelLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRA-DLAELAALRAELEA 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1390011543 475 TVEELRSTADSAAGSTSKILKVEKENQRLNKKveiLENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENS 549
Cdd:COG4942 172 ERAELEALLAELEEERAALEALKAERQKLLAR---LEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
|
| KpsE |
COG3524 |
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis]; |
1056-1137 |
5.22e-03 |
|
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442746 [Multi-domain] Cd Length: 370 Bit Score: 41.37 E-value: 5.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1056 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQnttLQTQNAKL--QVENSTLNSQST-----SLMNQNAQL 1128
Cdd:COG3524 224 ATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALEKQ---IAAERARLtgASGGDSLASLLAeyerlELEREFAEK 300
|
90
....*....|.
gi 1390011543 1129 LIQQS--SLEN 1137
Cdd:COG3524 301 AYTSAlaALEQ 311
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
625-786 |
5.50e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.68 E-value: 5.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 625 ERAEELENELNHLGKENELLQKKITNLKITCEKLET----LEQENSELERENRKFKKTLDSFKN------LTFQLESLEK 694
Cdd:COG1579 24 HRLKELPAELAELEDELAALEARLEAAKTELEDLEKeikrLELEIEEVEARIKKYEEQLGNVRNnkeyeaLQKEIESLKR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 695 ENSQLDEENLELRRSVESLKcasmrmAQLQLENKELESEKEQLRKglelmrasfKKTErlevsyqgLDTENQRLQKALEN 774
Cdd:COG1579 104 RISDLEDEILELMERIEELE------EELAELEAELAELEAELEE---------KKAE--------LDEELAELEAELEE 160
|
170
....*....|..
gi 1390011543 775 SNKKIQQLESEL 786
Cdd:COG1579 161 LEAEREELAAKI 172
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
592-947 |
6.27e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.42 E-value: 6.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 592 LHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNhlgkenELLQKKITNLKITCEKLETLEQENSELERE 671
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELE------SRVAELKEELRQSREKHEELEEKYKELSAS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 672 NrkfkktldsfknltfqlESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENK-ELESEKEQLRKGLELMRASFKK 750
Cdd:pfam07888 110 S-----------------EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLEREtELERMKERAKKAGAQRKEEEAE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 751 TERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Cdd:pfam07888 173 RKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 831 KKQLEKE-----NKRLRQQAEIKDTTLEENNVKI-------------GNLEKENKTLFKEINVYKESCVRL-KELEKENK 891
Cdd:pfam07888 253 VEGLGEElssmaAQRDRTQAELHQARLQAAQLTLqladaslalregrARWAQERETLQQSAEADKDRIEKLsAELQRLEE 332
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1390011543 892 ELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQ 947
Cdd:pfam07888 333 RLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQ 388
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
883-1121 |
6.35e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.54 E-value: 6.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 883 LKELEKENKELVKRATIDIKTLvTLREDLVSEKLKTQQmnndleKLTHELEKigLNKERLLHDEQSTDDSRykllesKLE 962
Cdd:PHA02562 165 LSEMDKLNKDKIRELNQQIQTL-DMKIDHIQQQIKTYN------KNIEEQRK--KNGENIARKQNKYDELV------EEA 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 963 STLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNyeaLKQRQDEERMVQS-------SIPVSGEDDKW----- 1030
Cdd:PHA02562 230 KTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSK---IEQFQKVIKMYEKggvcptcTQQISEGPDRItkikd 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1031 -GRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV 1109
Cdd:PHA02562 307 kLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386
|
250
....*....|..
gi 1390011543 1110 ENSTLNSQSTSL 1121
Cdd:PHA02562 387 ELDKIVKTKSEL 398
|
|
| WEMBL |
pfam05701 |
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required ... |
602-931 |
6.46e-03 |
|
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photo-relocation movement via the regulation of cp-actin filaments. Thus several member-sequences are described as "myosin heavy chain-like".
Pssm-ID: 461718 [Multi-domain] Cd Length: 562 Bit Score: 41.17 E-value: 6.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 602 KLSKIEFEKrqMKKELELYKEKGERAEELENE-LNHLGKENELlqkkITNLKITCEKLETLEQ---ENSELerenrkfkk 677
Cdd:pfam05701 38 KLVELELEK--VQEEIPEYKKQSEAAEAAKAQvLEELESTKRL----IEELKLNLERAQTEEAqakQDSEL--------- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 678 tldsfknltFQLESLEKENSQLDEENLELRRSVESLKcasmrmAQLQLENKELESEKEQLrkglelmrasfkktERLEVS 757
Cdd:pfam05701 103 ---------AKLRVEEMEQGIADEASVAAKAQLEVAK------ARHAAAVAELKSVKEEL--------------ESLRKE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 758 YQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEelkisSKRLEQLEKENKSL------EQETSQLEKDK 831
Cdd:pfam05701 154 YASLVSERDIAIKRAEEAVSASKEIEKTVEELTIELIATKESLE-----SAHAAHLEAEEHRIgaalarEQDKLNWEKEL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 832 KQLEKENKRLRQQ---AEIKDTTLEENNVKIGNLEkenktlfKEINVYKEScvRLKELEKENKElvkratiDIKTLVTLR 908
Cdd:pfam05701 229 KQAEEELQRLNQQllsAKDLKSKLETASALLLDLK-------AELAAYMES--KLKEEADGEGN-------EKKTSTSIQ 292
|
330 340
....*....|....*....|...
gi 1390011543 909 EDLVSEKLKTQQMNNDLEKLTHE 931
Cdd:pfam05701 293 AALASAKKELEEVKANIEKAKDE 315
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1032-1171 |
6.60e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.04 E-value: 6.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1032 RESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVEN 1111
Cdd:COG4372 45 EELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKER 124
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1112 STLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQA 1171
Cdd:COG4372 125 QDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQA 184
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
242-843 |
6.96e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 41.35 E-value: 6.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 242 RTESRQHLsVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMnllsdarsarmyrdeldALREKAVR 321
Cdd:pfam10174 156 RDESIKKL-LEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENI-----------------HLREELHR 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 322 VDKLESELSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLE-GTRARSDKLHELEKENLQLKAKLHDMEMERDM 400
Cdd:pfam10174 218 RNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLlHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQE 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 401 DRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKslghEVNELTssklLKLEMENQSLTKTVEELR 480
Cdd:pfam10174 298 LSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQT----EVDALR----LRLEEKESFLNKKTKQLQ 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 481 STADSAAGSTSKI------LKV-EKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEK--------------AQLE 539
Cdd:pfam10174 370 DLTEEKSTLAGEIrdlkdmLDVkERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSsntdtalttleealSEKE 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 540 KTIETLRENSERQIKILEQENEHLNQTVSSLRQrsQISAEARVKdIEKENKILheSIKETCGKLSKIEFEKRQMKKELEL 619
Cdd:pfam10174 450 RIIERLKEQREREDRERLEELESLKKENKDLKE--KVSALQPEL-TEKESSLI--DLKEHASSLASSGLKKDSKLKSLEI 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 620 YKEKgeRAEELENELNHLGKENELLQKKITNLKITcEKLETLEQENSELERENRKFKKTLDSFKNLTFQLES--LEKENS 697
Cdd:pfam10174 525 AVEQ--KKEECSKLENQLKKAHNAEEAVRTNPEIN-DRIRLLEQEVARYKEESGKAQAEVERLLGILREVENekNDKDKK 601
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 698 QLDEENLELRRSVE-SLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKK-----TERLEVSYQGLDTENQRL--- 768
Cdd:pfam10174 602 IAELESLTLRQMKEqNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLqleelMGALEKTRQELDATKARLsst 681
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 769 QKALENSNKKIQQLESELQD-----LEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Cdd:pfam10174 682 QQSLAEKDGHLTNLRAERRKqleeiLEMKQEALLAAISEKDANIALLELSSSKKKKTQEEVMALKREKDRLVHQLKQQTQ 761
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
810-851 |
7.14e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.35 E-value: 7.14e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1390011543 810 LEQLEKENKSLEQETSQLEKDK---KQLEKENKRLRQQAEIKDTT 851
Cdd:PRK13922 71 LFDLREENEELKKELLELESRLqelEQLEAENARLRELLNLKESL 115
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
697-868 |
7.19e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 41.35 E-value: 7.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 697 SQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQgldteNQRLQKALENSN 776
Cdd:PRK00409 509 KLIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEA-----EKEAQQAIKEAK 583
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 777 KKIQQLESELQDLEMENQTLQKSleelKISSKRLEQLEKENKSLEQETSQLEKDKKQLeKENKRLR-----QQAEI---- 847
Cdd:PRK00409 584 KEADEIIKELRQLQKGGYASVKA----HELIEARKRLNKANEKKEKKKKKQKEKQEEL-KVGDEVKylslgQKGEVlsip 658
|
170 180
....*....|....*....|....*..
gi 1390011543 848 --KDTTLEEN----NVKIGNLEKENKT 868
Cdd:PRK00409 659 ddKEAIVQAGimkmKVPLSDLEKIQKP 685
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
719-889 |
7.21e-03 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 39.89 E-value: 7.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 719 RMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQG------------------LDTENQRLQKALENSNKKIQ 780
Cdd:pfam15619 12 KIKELQNELAELQSKLEELRKENRLLKRLQKRQEKALGKYEGteselpqliarhneevrvLRERLRRLQEKERDLERKLK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 781 QLESELQDLEMENQTLQ-----KSLEELKISSKRLEQLEKEnksLEQETSQLEKDKKQLEKENKRLRQQaeikdttLEEN 855
Cdd:pfam15619 92 EKEAELLRLRDQLKRLEklsedKNLAEREELQKKLEQLEAK---LEDKDEKIQDLERKLELENKSFRRQ-------LAAE 161
|
170 180 190
....*....|....*....|....*....|....
gi 1390011543 856 NVKIGNLEKENKTLFKEINVYKEscvRLKELEKE 889
Cdd:pfam15619 162 KKKHKEAQEEVKILQEEIERLQQ---KLKEKERE 192
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
260-525 |
7.35e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 40.56 E-value: 7.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 260 IRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLsdARSARMYRDELDALREKAVRVDKLESELSRYKERLHDI 339
Cdd:pfam15905 82 IRALVQERGEQDKRLQALEEELEKVEAKLNAAVREKTSLS--ASVASLEKQLLELTRVNELLKAKFSEDGTQKKMSSLSM 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 340 EFYKARvEELKEDNQVLLETKTMLEDQLEGTRarsDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQ 419
Cdd:pfam15905 160 ELMKLR-NKLEAKMKEVMAKQEGMEGKLQVTQ---KNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVS 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 420 KQsmdeslhlgweLEQISRTSELAEAPQKSLGHEVNELTSSkllkLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKE 499
Cdd:pfam15905 236 EQ-----------VEKYKLDIAQLEELLKEKNDEIESLKQS----LEEKEQELSKQIKDLNEKCKLLESEKEELLREYEE 300
|
250 260
....*....|....*....|....*..
gi 1390011543 500 -NQRLNKKVEILENEIIQEKQSLQNCQ 525
Cdd:pfam15905 301 kEQTLNAELEELKEKLTLEEQEHQKLQ 327
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1051-1299 |
7.43e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.16 E-value: 7.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1051 VERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT--VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQL 1128
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1129 liqQSSLENENESIMKEREDlkSLYDALIKDHEKLEllherqaSEYESLISKHGtlksahknlevehkdleDRYNQLLKQ 1208
Cdd:COG3206 246 ---RAQLGSGPDALPELLQS--PVIQQLRAQLAELE-------AELAELSARYT-----------------PNHPDVIAL 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1209 KGQLEDLEKMIKTEQEKMLLESKNhevvasEYKKLCGENDRLNYTYSQLLKETeilqmdhknlkSVLNNSKLEQTRLEAE 1288
Cdd:COG3206 297 RAQIAALRAQLQQEAQRILASLEA------ELEALQAREASLQAQLAQLEARL-----------AELPELEAELRRLERE 359
|
250
....*....|.
gi 1390011543 1289 FSKLKEQYQQL 1299
Cdd:COG3206 360 VEVARELYESL 370
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
257-605 |
7.79e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 41.38 E-value: 7.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 257 KAKIRRLRQELEEKTEQLLDCKQEL----EQIEVE-LKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLEselsr 331
Cdd:PLN03229 428 KTPVRELEGEVEKLKEQILKAKESSskpsELALNEmIEKLKKEIDLEYTEAVIAMGLQERLENLREEFSKANSQD----- 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 332 ykERLHDIefYKARVEELKEDNQVLLETK---TMLEDQLEGTRA--RSDKLHELEKENLQLKAKLHDM---EMERDMDRK 403
Cdd:PLN03229 503 --QLMHPV--LMEKIEKLKDEFNKRLSRApnyLSLKYKLDMLNEfsRAKALSEKKSKAEKLKAEINKKfkeVMDRPEIKE 578
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 404 KIEELMEENMTLEMAQKQSMDESLhlgweLEQISRTS-----ELAEApQKSLGHEVNELTSSKLLKLEmenqslTKTVEE 478
Cdd:PLN03229 579 KMEALKAEVASSGASSGDELDDDL-----KEKVEKMKkeielELAGV-LKSMGLEVIGVTKKNKDTAE------QTPPPN 646
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 479 LRStadsaagstskilKVEKENQRLNKKVEileneiiqekqSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ 558
Cdd:PLN03229 647 LQE-------------KIESLNEEINKKIE-----------RVIRSSDLKSKIELLKLEVAKASKTPDVTEKEKIEALEQ 702
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1390011543 559 EnehLNQTVSSLRQRSQIsaEARVKDIEKENKILHESIKETCGKLSK 605
Cdd:PLN03229 703 Q---IKQKIAEALNSSEL--KEKFEELEAELAAARETAAESNGSLKN 744
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
455-1323 |
8.25e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.19 E-value: 8.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 455 NELTSSKLLKLEMENQSLTKTVEE----LRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIiqekqslqncqnlsKD 530
Cdd:TIGR01612 518 DEVPSKNIIGFDIDQNIKAKLYKEieagLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEI--------------KD 583
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 531 LMKEKAQLEKT---IETLRENSERQIKILEQENEHLNQTVSslrqrsqisaeaRVKDIEKENKILHESIKETCGKLSKIE 607
Cdd:TIGR01612 584 LFDKYLEIDDEiiyINKLKLELKEKIKNISDKNEYIKKAID------------LKKIIENNNAYIDELAKISPYQVPEHL 651
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 608 FEKRQMKKEL--ELYKEKGERAEELENELNHLGKENEL-----------LQKKITNL--KITCEKLETLEQENSELERE- 671
Cdd:TIGR01612 652 KNKDKIYSTIksELSKIYEDDIDALYNELSSIVKENAIdntedkaklddLKSKIDKEydKIQNMETATVELHLSNIENKk 731
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 672 ------------------NRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKcaSMRMAQLQLENKELESE 733
Cdd:TIGR01612 732 nelldiiveikkhihgeiNKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIK--NHYNDQINIDNIKDEDA 809
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 734 KEQLRKGLELMRA-SFKKTERLEVSYQGLDTENQRLQKAlensNKKIQQLESELQDLEMENQTLQKSLEELK--ISSKRL 810
Cdd:TIGR01612 810 KQNYDKSKEYIKTiSIKEDEIFKIINEMKFMKDDFLNKV----DKFINFENNCKEKIDSEHEQFAELTNKIKaeISDDKL 885
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 811 EQLEK---ENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEScvrlKELE 887
Cdd:TIGR01612 886 NDYEKkfnDSKSLINEINKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKNIDTIKES----NLIE 961
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 888 KENKELVKRATIDIKTlvTLREDLVSEKLKT-QQMNNDLEKLTHEL-EKIGLNKERLLH-----DEQSTDDSRYKLLE-- 958
Cdd:TIGR01612 962 KSYKDKFDNTLIDKIN--ELDKAFKDASLNDyEAKNNELIKYFNDLkANLGKNKENMLYhqfdeKEKATNDIEQKIEDan 1039
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 959 ---SKLESTLKKSLEIKEEKIAALEARLEESTNYN--QQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRE 1033
Cdd:TIGR01612 1040 kniPNIEIAIHTSIYNIIDEIEKEIGKNIELLNKEilEEAEINITNFNEIKEKLKHYNFDDFGKEENIKYADEINKIKDD 1119
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1034 SQEATRELLKVKDRLIEVERNNATLQAEkqaLKTQLKQLE-----TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQ 1108
Cdd:TIGR01612 1120 IKNLDQKIDHHIKALEEIKKKSENYIDE---IKAQINDLEdvadkAISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLL 1196
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1109 VENSTLNSQSTSL-----MNQNAQLLIQQSSLENENESIMKEREDLKSLyDALIKDHEKLellhERQASEYESLISKHGT 1183
Cdd:TIGR01612 1197 NEIAEIEKDKTSLeevkgINLSYGKNLGKLFLEKIDEEKKKSEHMIKAM-EAYIEDLDEI----KEKSPEIENEMGIEMD 1271
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 1184 LKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKM----------------IKTEQEKMLLESKNHevvaseykklcgeN 1247
Cdd:TIGR01612 1272 IKAEMETFNISHDDDKDHHIISKKHDENISDIREKslkiiedfseesdindIKKELQKNLLDAQKH-------------N 1338
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1390011543 1248 DRLNYTYSQLLKETEILQMDhkNLKSVLNNSKleqtrleaEFSKLKEQYQQldITSTKLNNQCELLSQLKGNLEEE 1323
Cdd:TIGR01612 1339 SDINLYLNEIANIYNILKLN--KIKKIIDEVK--------EYTKEIEENNK--NIKDELDKSEKLIKKIKDDINLE 1402
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
608-742 |
8.45e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.92 E-value: 8.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 608 FEKRQMKKELELYKEKGER-AEELENELNHLGKENEL-LQKKITNLKITCEKleTLEQENSELErenRKFKKTLDSFKNL 685
Cdd:PRK12704 24 VRKKIAEAKIKEAEEEAKRiLEEAKKEAEAIKKEALLeAKEEIHKLRNEFEK--ELRERRNELQ---KLEKRLLQKEENL 98
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1390011543 686 TFQLESLEKENSQLDEENLELRRsveslkcasmRMAQLQLENKELESEKEQLRKGLE 742
Cdd:PRK12704 99 DRKLELLEKREEELEKKEKELEQ----------KQQELEKKEEELEELIEEQLQELE 145
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
278-411 |
8.66e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.00 E-value: 8.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 278 KQELEQIEVELKRLQQENMNLlsdarsarmyRDELDALREkavRVDKLESELSRYKERLHDIEFYKARVEELKEDNQvll 357
Cdd:COG2433 412 EEEIRRLEEQVERLEAEVEEL----------EAELEEKDE---RIERLERELSEARSEERREIRKDREISRLDREIE--- 475
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 358 etktMLEDQLEGTRARsdkLHELEKENLQLKaKLHDMEMERDM---------DRKKIEELMEE 411
Cdd:COG2433 476 ----RLERELEEERER---IEELKRKLERLK-ELWKLEHSGELvpvkvvekfTKEAIRRLEEE 530
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
814-1040 |
8.67e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.58 E-value: 8.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKEscvRLKELEKENKEL 893
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEA---EIEERREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 894 VKRATIDIKTLVTLREDLVSEKLktQQMNNDLEKLTheleKIGLNKERLLhDEQSTDDSRYKLLESKLE---STLKKSLE 970
Cdd:COG3883 92 ARALYRSGGSVSYLDVLLGSESF--SDFLDRLSALS----KIADADADLL-EELKADKAELEAKKAELEaklAELEALKA 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 971 IKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRE 1040
Cdd:COG3883 165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAA 234
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
244-411 |
9.36e-03 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 40.28 E-value: 9.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSarmYRDELDALREKAVRVD 323
Cdd:COG1340 29 EKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKLNE---LREELDELRKELAELN 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 324 KLESELSRYKERLHDIEF-YKARVEELKEDNQVLLETKTmLEDQLEGTRarsdKLHELEKENLQLKAKLHDMEMERDMDR 402
Cdd:COG1340 106 KAGGSIDKLRKEIERLEWrQQTEVLSPEEEKELVEKIKE-LEKELEKAK----KALEKNEKLKELRAELKELRKEAEEIH 180
|
....*....
gi 1390011543 403 KKIEELMEE 411
Cdd:COG1340 181 KKIKELAEE 189
|
|
| HAP1_N |
pfam04849 |
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found ... |
625-804 |
9.90e-03 |
|
HAP1 N-terminal conserved region; This family represents an N-terminal conserved region found in several huntingtin-associated protein 1 (HAP1) homologs. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner. However, its possible role in the pathogenesis of Huntington's disease is unclear. This family also includes a similar N-terminal conserved region from hypothetical protein products of ALS2CR3 genes found in the human juvenile amyotrophic lateral sclerosis critical region 2q33-2q34.
Pssm-ID: 461455 [Multi-domain] Cd Length: 309 Bit Score: 40.39 E-value: 9.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 625 ERAEELENEL-------NHLGKEnelLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFknlTFQLESLEKENS 697
Cdd:pfam04849 101 ERNEALEEQLgsareeiLQLRHE---LSKKDDLLQIYSNDAEESETESSCSTPLRRNESFSSLHG---CVQLDALQEKLR 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390011543 698 QLDEENLELRRS----------------------VESLKCASMRMAQLQLENKELESEKEQLRKGLELMRAsfkKTERLE 755
Cdd:pfam04849 175 GLEEENLKLRSEashlktetdtyeekeqqlmsdcVEQLSEANQQMAELSEELARKMEENLRQQEEITSLLA---QIVDLQ 251
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 1390011543 756 VSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQT----LQKSLEELK 804
Cdd:pfam04849 252 HKCKELGIENEELQQHLQASKEAQRQLTSELQELQDRYAEclgmLHEAQEELK 304
|
|
| |
