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Conserved domains on  [gi|1375023016|ref|NP_001349039|]
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protein FAM234B isoform 1 [Mus musculus]

Protein Classification

PQQ-binding-like beta-propeller repeat protein( domain architecture ID 29103)

PQQ (pyrroloquinoline quinone)-binding-like beta-propeller repeat protein

Gene Ontology:  GO:0070968
PubMed:  16232604|11831471

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PQQ super family cl34291
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
132-265 2.57e-04

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG1520:

Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 43.65  E-value: 2.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375023016 132 DLHSAWSRRLGSQGGGDLSPLELADVNrdglrDVLltFVTTRNGT---------------------EGGVGSQ------- 183
Cdd:COG1520    31 KVKQLWSASVGDGVGKGYSRLAPAVAG-----DRV--YAADADGRvaaldaatgkelwrvdlgeplSGGVGADgglvvvg 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375023016 184 -PTADLVCLSGMNGSTLWSSPLPEEAqdvtcldLIPGSVAKTICLVTGTRKMLSAFNATSGKVLWTLN---PNhLSNGTL 259
Cdd:COG1520   104 tEDGEVIALDADDGEELWRARLSSEV-------LAAPAVAGGRVVVRTGDGRVYALDAATGERLWSYQrpvPA-LTLRGT 175

                  ....*.
gi 1375023016 260 AAPVVV 265
Cdd:COG1520   176 SSPVIV 181
 
Name Accession Description Interval E-value
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
132-265 2.57e-04

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 43.65  E-value: 2.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375023016 132 DLHSAWSRRLGSQGGGDLSPLELADVNrdglrDVLltFVTTRNGT---------------------EGGVGSQ------- 183
Cdd:COG1520    31 KVKQLWSASVGDGVGKGYSRLAPAVAG-----DRV--YAADADGRvaaldaatgkelwrvdlgeplSGGVGADgglvvvg 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375023016 184 -PTADLVCLSGMNGSTLWSSPLPEEAqdvtcldLIPGSVAKTICLVTGTRKMLSAFNATSGKVLWTLN---PNhLSNGTL 259
Cdd:COG1520   104 tEDGEVIALDADDGEELWRARLSSEV-------LAAPAVAGGRVVVRTGDGRVYALDAATGERLWSYQrpvPA-LTLRGT 175

                  ....*.
gi 1375023016 260 AAPVVV 265
Cdd:COG1520   176 SSPVIV 181
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
129-285 5.32e-04

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 42.61  E-value: 5.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375023016 129 PPRDLHSAWSRRLGSQGGGDLSPLELADVN-------RDGL--------RDVLLTfVTTRNGTEGGVGS--------QPT 185
Cdd:TIGR03300  36 PTVKVDQVWSASVGDGVGHYYLRLQPAVAGgkvyaadADGTvaaldaetGKRLWR-VDLDERLSGGVGAdgglvfvgTEK 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375023016 186 ADLVCLSGMNGSTLWSSPLPEEAqdvtcldLIPGSVAKTICLVTGTRKMLSAFNATSGKVLWTLNpNHLSNGTL---AAP 262
Cdd:TIGR03300 115 GEVIALDAEDGKELWRAKLSSEV-------LSPPLVANGLVVVRTNDGRLTALDAATGERLWTYS-RVTPPLTLrgsASP 186
                         170       180
                  ....*....|....*....|...
gi 1375023016 263 VVVlpdldEDGVrdLVVLAIGEL 285
Cdd:TIGR03300 187 VIA-----DGGV--LVGFAGGKL 202
 
Name Accession Description Interval E-value
PQQ COG1520
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ...
132-265 2.57e-04

Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 441129 [Multi-domain]  Cd Length: 370  Bit Score: 43.65  E-value: 2.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375023016 132 DLHSAWSRRLGSQGGGDLSPLELADVNrdglrDVLltFVTTRNGT---------------------EGGVGSQ------- 183
Cdd:COG1520    31 KVKQLWSASVGDGVGKGYSRLAPAVAG-----DRV--YAADADGRvaaldaatgkelwrvdlgeplSGGVGADgglvvvg 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375023016 184 -PTADLVCLSGMNGSTLWSSPLPEEAqdvtcldLIPGSVAKTICLVTGTRKMLSAFNATSGKVLWTLN---PNhLSNGTL 259
Cdd:COG1520   104 tEDGEVIALDADDGEELWRARLSSEV-------LAAPAVAGGRVVVRTGDGRVYALDAATGERLWSYQrpvPA-LTLRGT 175

                  ....*.
gi 1375023016 260 AAPVVV 265
Cdd:COG1520   176 SSPVIV 181
assembly_YfgL TIGR03300
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ...
129-285 5.32e-04

outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274511 [Multi-domain]  Cd Length: 377  Bit Score: 42.61  E-value: 5.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375023016 129 PPRDLHSAWSRRLGSQGGGDLSPLELADVN-------RDGL--------RDVLLTfVTTRNGTEGGVGS--------QPT 185
Cdd:TIGR03300  36 PTVKVDQVWSASVGDGVGHYYLRLQPAVAGgkvyaadADGTvaaldaetGKRLWR-VDLDERLSGGVGAdgglvfvgTEK 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1375023016 186 ADLVCLSGMNGSTLWSSPLPEEAqdvtcldLIPGSVAKTICLVTGTRKMLSAFNATSGKVLWTLNpNHLSNGTL---AAP 262
Cdd:TIGR03300 115 GEVIALDAEDGKELWRAKLSSEV-------LSPPLVANGLVVVRTNDGRLTALDAATGERLWTYS-RVTPPLTLrgsASP 186
                         170       180
                  ....*....|....*....|...
gi 1375023016 263 VVVlpdldEDGVrdLVVLAIGEL 285
Cdd:TIGR03300 187 VIA-----DGGV--LVGFAGGKL 202
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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