NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1372261832|ref|NP_001348966|]
View 

cAMP-regulated phosphoprotein 21 isoform 14 [Mus musculus]

Protein Classification

R3H_encore_like domain-containing protein( domain architecture ID 12927546)

R3H_encore_like domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
R3H_encore_like cd02642
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ...
 162-223 8.28e-26

R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


:

Pssm-ID: 100071  Cd Length: 63  Bit Score: 100.75  E-value: 8.28e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1372261832 162 DRMILLKMEQEMIDFIADSNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG-KSVIINKT 223
Cdd:cd02642     1 DRLFVLKLEKDLLAFIKDSTRQSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGgKCVIVNKT 63
PAT1 super family cl37801
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 520-749 5.54e-06

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


The actual alignment was detected with superfamily member pfam09770:

Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 50.03  E-value: 5.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 520 QLSMSRQssgdtpEPPSGTVYPASLLPQTAQPQSYVITSAGQQLS----TG--GFSDSGPPISQQVLQA----PPSPQGF 589
Cdd:pfam09770  99 QVRFNRQ------QPAARAAQSSAQPPASSLPQYQYASQQSQQPSkpvrTGyeKYKEPEPIPDLQVDASlwgvAPKKAAA 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 590 VQQPPPAQMSvyyypsgqyPTSTSQQYRPLASVQY--SAQRSQQIPQTTQQA-------GYQPVLSGQQGFQGMMGVQQS 660
Cdd:pfam09770 173 PAPAPQPAAQ---------PASLPAPSRKMMSLEEveAAMRAQAKKPAQQPApapaqppAAPPAQQAQQQQQFPPQIQQQ 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 661 AHSQGVMSSQQGAPVHGVMVS---YPTMSSYQVPMTQGSQAVPQQTYQPP--IMLPSQAGQ--GSLPATGMPVYCNVTPP 733
Cdd:pfam09770 244 QQPQQQPQQPQQHPGQGHPVTilqRPQSPQPDPAQPSIQPQAQQFHQQPPpvPVQPTQILQnpNRLSAARVGYPQNPQPG 323

                         250
                  ....*....|....*.
gi 1372261832 734 NPQNNLRLMGPHCPSS 749
Cdd:pfam09770 324 VQPAPAHQAHRQQGSF 339
 
Name Accession Description Interval E-value
R3H_encore_like cd02642
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ...
 162-223 8.28e-26

R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100071  Cd Length: 63  Bit Score: 100.75  E-value: 8.28e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1372261832 162 DRMILLKMEQEMIDFIADSNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG-KSVIINKT 223
Cdd:cd02642     1 DRLFVLKLEKDLLAFIKDSTRQSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGgKCVIVNKT 63
R3H smart00393
Putative single-stranded nucleic acids-binding domain;
146-223 3.25e-13

Putative single-stranded nucleic acids-binding domain;


Pssm-ID: 214647  Cd Length: 79  Bit Score: 65.40  E-value: 3.25e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  146 IDLHGFLINTLKNNSRDRMILLKMEQEMIDFIAdSNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG--KSVIINKT 223
Cdd:smart00393   1 ADFLPVTLDALSYRPRRREELIELELEIARFVK-STKESVELPPMNSYERKIVHELAEKYGLESESFGEGpkRRVVISKK 79
R3H pfam01424
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most ...
 164-222 2.71e-12

R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA.


Pssm-ID: 460206  Cd Length: 60  Bit Score: 62.12  E-value: 2.71e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1372261832 164 MILLKMEQEMIDFIADSNNHYKkFPQMSSYQRMLVHRVAAYFGLDHNV--DQTGKSVIINK 222
Cdd:pfam01424   1 EFLEQLAEKLAEFVKDTGKSLE-LPPMSSYERRIIHELAQKYGLESESegEEPNRRVVVYK 60
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 520-749 5.54e-06

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 50.03  E-value: 5.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 520 QLSMSRQssgdtpEPPSGTVYPASLLPQTAQPQSYVITSAGQQLS----TG--GFSDSGPPISQQVLQA----PPSPQGF 589
Cdd:pfam09770  99 QVRFNRQ------QPAARAAQSSAQPPASSLPQYQYASQQSQQPSkpvrTGyeKYKEPEPIPDLQVDASlwgvAPKKAAA 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 590 VQQPPPAQMSvyyypsgqyPTSTSQQYRPLASVQY--SAQRSQQIPQTTQQA-------GYQPVLSGQQGFQGMMGVQQS 660
Cdd:pfam09770 173 PAPAPQPAAQ---------PASLPAPSRKMMSLEEveAAMRAQAKKPAQQPApapaqppAAPPAQQAQQQQQFPPQIQQQ 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 661 AHSQGVMSSQQGAPVHGVMVS---YPTMSSYQVPMTQGSQAVPQQTYQPP--IMLPSQAGQ--GSLPATGMPVYCNVTPP 733
Cdd:pfam09770 244 QQPQQQPQQPQQHPGQGHPVTilqRPQSPQPDPAQPSIQPQAQQFHQQPPpvPVQPTQILQnpNRLSAARVGYPQNPQPG 323

                         250
                  ....*....|....*.
gi 1372261832 734 NPQNNLRLMGPHCPSS 749
Cdd:pfam09770 324 VQPAPAHQAHRQQGSF 339
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 510-733 1.51e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.46  E-value: 1.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  510 QREELAAQFSQLSMSR---QSSGDTPEPP--SGTVYPASLLPQTAQPQsyvitsagQQLSTGGFSDSGPPISQQVLQAPP 584
Cdd:PRK10263   660 QQDELARQFAQTQQQRygeQYQHDVPVNAedADAAAEAELARQFAQTQ--------QQRYSGEQPAGANPFSLDDFEFSP 731

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  585 SpQGFVQQPPPAQMsvyyYPSGQYPTSTSQQyRPLASVQYSAQRSQQIPQTTQQAGYQPVLSGQQGFQGMMGVQQSAHSQ 664
Cdd:PRK10263   732 M-KALLDDGPHEPL----FTPIVEPVQQPQQ-PVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQ 805

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  665 GVMSSQQGAPvhgvmvsyptmsSYQVPMtqgSQAVPQQTYQPPIMLPSQAGQGSL----------------PATGMPVYC 728
Cdd:PRK10263   806 QPQQPVAPQP------------QYQQPQ---QPVAPQPQYQQPQQPVAPQPQDTLlhpllmrngdsrplhkPTTPLPSLD 870


                   ....*
gi 1372261832  729 NVTPP 733
Cdd:PRK10263   871 LLTPP 875
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 510-648 9.96e-04

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 42.49  E-value: 9.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 510 QREELAAQFSQLSM-SRQSSGDTPEPPSgtvYPASLLPQTAQPQSYvitsAGQQLstgGFSDSGPPISQQVLQAPPSPQG 588
Cdd:TIGR01628 367 RRAHLQDQFMQLQPrMRQLPMGSPMGGA---MGQPPYYGQGPQQQF----NGQPL---GWPRMSMMPTPMGPGGPLRPNG 436

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 589 FVQQPPPAQMSVYYYPSGQYPTSTSQQYRPLASVQYSAQRSQQIPQTTQQAGYQPVLSGQ 648
Cdd:TIGR01628 437 LAPMNAVRAPSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQNKKLAQV 496
 
Name Accession Description Interval E-value
R3H_encore_like cd02642
R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the ...
 162-223 8.28e-26

R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H domain is a potential regulator of DBF1 activity in stress responses. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100071  Cd Length: 63  Bit Score: 100.75  E-value: 8.28e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1372261832 162 DRMILLKMEQEMIDFIADSNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG-KSVIINKT 223
Cdd:cd02642     1 DRLFVLKLEKDLLAFIKDSTRQSLELPPMNSYYRLLAHRVAQYYGLDHNVDNSGgKCVIVNKT 63
R3H smart00393
Putative single-stranded nucleic acids-binding domain;
146-223 3.25e-13

Putative single-stranded nucleic acids-binding domain;


Pssm-ID: 214647  Cd Length: 79  Bit Score: 65.40  E-value: 3.25e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  146 IDLHGFLINTLKNNSRDRMILLKMEQEMIDFIAdSNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG--KSVIINKT 223
Cdd:smart00393   1 ADFLPVTLDALSYRPRRREELIELELEIARFVK-STKESVELPPMNSYERKIVHELAEKYGLESESFGEGpkRRVVISKK 79
R3H pfam01424
R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most ...
 164-222 2.71e-12

R3H domain; The name of the R3H domain comes from the characteriztic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to be binding ssDNA.


Pssm-ID: 460206  Cd Length: 60  Bit Score: 62.12  E-value: 2.71e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1372261832 164 MILLKMEQEMIDFIADSNNHYKkFPQMSSYQRMLVHRVAAYFGLDHNV--DQTGKSVIINK 222
Cdd:pfam01424   1 EFLEQLAEKLAEFVKDTGKSLE-LPPMSSYERRIIHELAQKYGLESESegEEPNRRVVVYK 60
R3H cd02325
R3H domain. The name of the R3H domain comes from the characteristic spacing of the most ...
 166-222 3.29e-12

R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich repeats, ring-type zinc fingers, and KH domains. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100064  Cd Length: 59  Bit Score: 61.86  E-value: 3.29e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1372261832 166 LLKMEQEMIDFIADSNNHYKKFPQMSSYQRMLVHRVAAYFGLDHNVDQTG--KSVIINK 222
Cdd:cd02325     1 REEREEELEAFAKDAAGKSLELPPMNSYERKLIHDLAEYYGLKSESEGEGpnRRVVITK 59
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 520-749 5.54e-06

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 50.03  E-value: 5.54e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 520 QLSMSRQssgdtpEPPSGTVYPASLLPQTAQPQSYVITSAGQQLS----TG--GFSDSGPPISQQVLQA----PPSPQGF 589
Cdd:pfam09770  99 QVRFNRQ------QPAARAAQSSAQPPASSLPQYQYASQQSQQPSkpvrTGyeKYKEPEPIPDLQVDASlwgvAPKKAAA 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 590 VQQPPPAQMSvyyypsgqyPTSTSQQYRPLASVQY--SAQRSQQIPQTTQQA-------GYQPVLSGQQGFQGMMGVQQS 660
Cdd:pfam09770 173 PAPAPQPAAQ---------PASLPAPSRKMMSLEEveAAMRAQAKKPAQQPApapaqppAAPPAQQAQQQQQFPPQIQQQ 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 661 AHSQGVMSSQQGAPVHGVMVS---YPTMSSYQVPMTQGSQAVPQQTYQPP--IMLPSQAGQ--GSLPATGMPVYCNVTPP 733
Cdd:pfam09770 244 QQPQQQPQQPQQHPGQGHPVTilqRPQSPQPDPAQPSIQPQAQQFHQQPPpvPVQPTQILQnpNRLSAARVGYPQNPQPG 323

                         250
                  ....*....|....*.
gi 1372261832 734 NPQNNLRLMGPHCPSS 749
Cdd:pfam09770 324 VQPAPAHQAHRQQGSF 339
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 510-733 1.51e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.46  E-value: 1.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  510 QREELAAQFSQLSMSR---QSSGDTPEPP--SGTVYPASLLPQTAQPQsyvitsagQQLSTGGFSDSGPPISQQVLQAPP 584
Cdd:PRK10263   660 QQDELARQFAQTQQQRygeQYQHDVPVNAedADAAAEAELARQFAQTQ--------QQRYSGEQPAGANPFSLDDFEFSP 731

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  585 SpQGFVQQPPPAQMsvyyYPSGQYPTSTSQQyRPLASVQYSAQRSQQIPQTTQQAGYQPVLSGQQGFQGMMGVQQSAHSQ 664
Cdd:PRK10263   732 M-KALLDDGPHEPL----FTPIVEPVQQPQQ-PVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQ 805

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  665 GVMSSQQGAPvhgvmvsyptmsSYQVPMtqgSQAVPQQTYQPPIMLPSQAGQGSL----------------PATGMPVYC 728
Cdd:PRK10263   806 QPQQPVAPQP------------QYQQPQ---QPVAPQPQYQQPQQPVAPQPQDTLlhpllmrngdsrplhkPTTPLPSLD 870


                   ....*
gi 1372261832  729 NVTPP 733
Cdd:PRK10263   871 LLTPP 875
PRK10927 PRK10927
cell division protein FtsN;
524-675 3.64e-04

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 43.52  E-value: 3.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 524 SRQSSGDTPEPPSG---TVYPASLLPQTAQPQSYVITSAGQQ---LSTGGFSDSGPPISQQVLQAPPSPQGFVQQPPPAQ 597
Cdd:PRK10927   91 SRQPGVRAPTEPSAggeVKTPEQLTPEQRQLLEQMQADMRQQptqLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQ 170

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1372261832 598 MSVYYYPSGQYPTSTSQQyrplasvQYSAQRSQQIPQTTQQAGYQPVLsgqqgfqgmmgvQQSAHSQGVMSSQQGAPV 675
Cdd:PRK10927  171 QSRTTEQSWQQQTRTSQA-------APVQAQPRQSKPASTQQPYQDLL------------QTPAHTTAQSKPQQAAPV 229
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 510-648 9.96e-04

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 42.49  E-value: 9.96e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 510 QREELAAQFSQLSM-SRQSSGDTPEPPSgtvYPASLLPQTAQPQSYvitsAGQQLstgGFSDSGPPISQQVLQAPPSPQG 588
Cdd:TIGR01628 367 RRAHLQDQFMQLQPrMRQLPMGSPMGGA---MGQPPYYGQGPQQQF----NGQPL---GWPRMSMMPTPMGPGGPLRPNG 436

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832 589 FVQQPPPAQMSVYYYPSGQYPTSTSQQYRPLASVQYSAQRSQQIPQTTQQAGYQPVLSGQ 648
Cdd:TIGR01628 437 LAPMNAVRAPSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTASQGGQNKKLAQV 496
PHA03247 PHA03247
large tegument protein UL36; Provisional
 389-700 1.79e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 1.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  389 RTHPQSTALTSSVAAGSPGCMAYSENGMGGQVPPSSTSYILLPLESATGIPPGSillnphtgqpfVNPDGTPAIYNPPGS 468
Cdd:PHA03247  2700 DPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG-----------PARPARPPTTAGPPA 2768

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  469 QQTLRGTVGGQPQQPPQQQPSPQPQQQVQASQPQMAGPLVTQREELAAqfsqlSMSRQSSGDTPEPPSGTVYPASLLPQT 548
Cdd:PHA03247  2769 PAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAA-----ALPPAASPAGPLPPPTSAQPTAPPPPP 2843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  549 AQPQSYvITSAGQQLSTGGFSDSGPPISQQVLQAPPS--PQGFVQQPPPAQ--MSVYYYPSGQYPTSTSQ-QYRPLASVQ 623
Cdd:PHA03247  2844 GPPPPS-LPLGGSVAPGGDVRRRPPSRSPAAKPAAPArpPVRRLARPAVSRstESFALPPDQPERPPQPQaPPPPQPQPQ 2922

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1372261832  624 YSAQRSQQiPQTTQQAGYQPVLSGQQGFQGmmgvqQSAHSQGVMSSQQGAPVHGvmvsyptmsSYQVPMTQGSQAVP 700
Cdd:PHA03247  2923 PPPPPQPQ-PPPPPPPRPQPPLAPTTDPAG-----AGEPSGAVPQPWLGALVPG---------RVAVPRFRVPQPAP 2984
R3H_sperm-antigen cd02636
R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. ...
 168-207 2.43e-03

R3H domain of a group of metazoan proteins that is related to the sperm-associated antigen 7. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100065  Cd Length: 61  Bit Score: 36.92  E-value: 2.43e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1372261832 168 KMEQEMIDFIADSNNHYKKFPQMSSYQRMLVHRVAAYFGL 207
Cdd:cd02636     3 SMEKEVSKFIKDSVRTREKFQPMDKVERSIVHDVAEVAGL 42
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 539-727 2.55e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.61  E-value: 2.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  539 VYPASLLPQTAQPQSYVITSAGQQLSTGGFSDSGPPISQQVLQapPSPQGFVQQPPPAQMSVYYYPSGQYPTSTSQQYRP 618
Cdd:PRK10263   332 SWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIA--PAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYA 409

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1372261832  619 LASVQYSAQrsQQIPQTTQQAGYQPVLSGQqgfqgmmgVQQSAHSQGVMSSQQGaPVHGVMVSYPTMSSYQVPMTQGSQA 698
Cdd:PRK10263   410 PAAEQPAQQ--PYYAPAPEQPAQQPYYAPA--------PEQPVAGNAWQAEEQQ-STFAPQSTYQTEQTYQQPAAQEPLY 478

                          170       180
                   ....*....|....*....|....*....
gi 1372261832  699 VPQQTYQPPIMLPSQAGQGSLPATGMPVY 727
Cdd:PRK10263   479 QQPQPVEQQPVVEPEPVVEETKPARPPLY 507
R3H_Smubp-2_like cd02641
R3H domain of Smubp-2_like proteins. Smubp-2_like proteins also contain a helicase_like and ...
 176-220 4.08e-03

R3H domain of Smubp-2_like proteins. Smubp-2_like proteins also contain a helicase_like and an AN1-like Zinc finger domain and have been shown to bind single-stranded DNA. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA.


Pssm-ID: 100070  Cd Length: 60  Bit Score: 36.18  E-value: 4.08e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1372261832 176 FIADSNNHYKKFP-QMSSYQRMLVHRVAAYFGLDHNVDQTGKSVII 220
Cdd:cd02641    11 FMKDPKATELEFPpTLSSHDRLLVHELAEELGLRHESTGEGSDRVI 56
R3H_unknown_2 cd06006
R3H domain of a group of fungal proteins with unknown function. The name of the R3H domain ...
 168-208 8.15e-03

R3H domain of a group of fungal proteins with unknown function. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.


Pssm-ID: 100076  Cd Length: 59  Bit Score: 35.42  E-value: 8.15e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1372261832 168 KMEQEMIDFIADSNNHYKKFPQMSSYQRMLVHRVAAYFGLD 208
Cdd:cd06006     3 QIESTLRKFINDKSKRSLRFPPMRSPQRAFIHELAKDYGLY 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH