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Conserved domains on  [gi|1320620193|ref|NP_001346337|]
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SCAN domain containing 3 isoform 2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4371 super family cl46273
Domain of unknown function (DUF4371);
281-395 2.20e-11

Domain of unknown function (DUF4371);


The actual alignment was detected with superfamily member pfam14291:

Pssm-ID: 480613  Cd Length: 236  Bit Score: 64.56  E-value: 2.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320620193 281 LSNDTvrrrIHDMSADILDQVVQEIKSAPLpicSIQLDESTDVANCLQLMVYVRYI-NDGDFKDEFLCCKPLERTaTALD 359
Cdd:pfam14291 129 IQNDI----VNCFSNEVTRSIIEEMDNDVF---GILVDETADASDKEQMAIVFRYVdKYGVPIERFIGVIHVQET-SSLS 200

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1320620193 360 VFEAVDSFLRQHEISWKSICGVCTDGAPATLGCQSG 395
Cdd:pfam14291 201 LKSAIDSLLKSLGISLKKLRSQCYDGASNMSGEFNG 236
COG3416 super family cl47320
Uncharacterized conserved protein, DUF2076 domain [Function unknown];
23-88 2.31e-05

Uncharacterized conserved protein, DUF2076 domain [Function unknown];


The actual alignment was detected with superfamily member COG3416:

Pssm-ID: 442642 [Multi-domain]  Cd Length: 237  Bit Score: 46.55  E-value: 2.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1320620193  23 GSPAAAPRQP-GLMAQMATTAAGVAvGSAVghtLGHAITGGFSGGGSAEPAKpdITYQEPQGAQLQN 88
Cdd:COG3416   134 GQPAAGPSGGgGFLGGALQTAAGVA-GGVL---LANALTGMFSGSHPGEGVG--GGGGEPGGAGEET 194
Dimer_Tnp_hAT super family cl05324
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 650-715 1.76e-04

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


The actual alignment was detected with superfamily member pfam05699:

Pssm-ID: 399013  Cd Length: 83  Bit Score: 40.71  E-value: 1.76e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1320620193 650 DFSTMPVTQFWVKCLQSYPVLSEMVLRLL-LPFpTTYLCETGFSSLLVIKSKYRSRLvvEDDLRCAL 715
Cdd:pfam05699  13 RNEDFDPLEWWKENSSRYPNLSKLARDILsIPV-SSAASERSFSTLGKVILESRNRL--EPLNVEAL 76
 
Name Accession Description Interval E-value
DUF4371 pfam14291
Domain of unknown function (DUF4371);
281-395 2.20e-11

Domain of unknown function (DUF4371);


Pssm-ID: 405048  Cd Length: 236  Bit Score: 64.56  E-value: 2.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320620193 281 LSNDTvrrrIHDMSADILDQVVQEIKSAPLpicSIQLDESTDVANCLQLMVYVRYI-NDGDFKDEFLCCKPLERTaTALD 359
Cdd:pfam14291 129 IQNDI----VNCFSNEVTRSIIEEMDNDVF---GILVDETADASDKEQMAIVFRYVdKYGVPIERFIGVIHVQET-SSLS 200

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1320620193 360 VFEAVDSFLRQHEISWKSICGVCTDGAPATLGCQSG 395
Cdd:pfam14291 201 LKSAIDSLLKSLGISLKKLRSQCYDGASNMSGEFNG 236
COG3416 COG3416
Uncharacterized conserved protein, DUF2076 domain [Function unknown];
23-88 2.31e-05

Uncharacterized conserved protein, DUF2076 domain [Function unknown];


Pssm-ID: 442642 [Multi-domain]  Cd Length: 237  Bit Score: 46.55  E-value: 2.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1320620193  23 GSPAAAPRQP-GLMAQMATTAAGVAvGSAVghtLGHAITGGFSGGGSAEPAKpdITYQEPQGAQLQN 88
Cdd:COG3416   134 GQPAAGPSGGgGFLGGALQTAAGVA-GGVL---LANALTGMFSGSHPGEGVG--GGGGEPGGAGEET 194
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 650-715 1.76e-04

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 40.71  E-value: 1.76e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1320620193 650 DFSTMPVTQFWVKCLQSYPVLSEMVLRLL-LPFpTTYLCETGFSSLLVIKSKYRSRLvvEDDLRCAL 715
Cdd:pfam05699  13 RNEDFDPLEWWKENSSRYPNLSKLARDILsIPV-SSAASERSFSTLGKVILESRNRL--EPLNVEAL 76
DUF2076 pfam09849
Uncharacterized protein conserved in bacteria (DUF2076); This domain, found in various ...
 23-74 8.42e-03

Uncharacterized protein conserved in bacteria (DUF2076); This domain, found in various hypothetical prokaryotic proteins, has no known function. The domain, however, is found in various periplasmic ligand-binding sensor proteins.


Pssm-ID: 430876  Cd Length: 263  Bit Score: 38.57  E-value: 8.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1320620193  23 GSPAAAPRQP-------GLMAQMATTAAGVAVGSavghTLGHAITGGFSGGGSAEPAKP 74
Cdd:pfam09849 140 GQPAQPPRGPwgpggggGFLGGALQTAAGVAGGV----LLAQGIESLFSGGHGGFGGGG 194
 
Name Accession Description Interval E-value
DUF4371 pfam14291
Domain of unknown function (DUF4371);
281-395 2.20e-11

Domain of unknown function (DUF4371);


Pssm-ID: 405048  Cd Length: 236  Bit Score: 64.56  E-value: 2.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1320620193 281 LSNDTvrrrIHDMSADILDQVVQEIKSAPLpicSIQLDESTDVANCLQLMVYVRYI-NDGDFKDEFLCCKPLERTaTALD 359
Cdd:pfam14291 129 IQNDI----VNCFSNEVTRSIIEEMDNDVF---GILVDETADASDKEQMAIVFRYVdKYGVPIERFIGVIHVQET-SSLS 200

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1320620193 360 VFEAVDSFLRQHEISWKSICGVCTDGAPATLGCQSG 395
Cdd:pfam14291 201 LKSAIDSLLKSLGISLKKLRSQCYDGASNMSGEFNG 236
COG3416 COG3416
Uncharacterized conserved protein, DUF2076 domain [Function unknown];
23-88 2.31e-05

Uncharacterized conserved protein, DUF2076 domain [Function unknown];


Pssm-ID: 442642 [Multi-domain]  Cd Length: 237  Bit Score: 46.55  E-value: 2.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1320620193  23 GSPAAAPRQP-GLMAQMATTAAGVAvGSAVghtLGHAITGGFSGGGSAEPAKpdITYQEPQGAQLQN 88
Cdd:COG3416   134 GQPAAGPSGGgGFLGGALQTAAGVA-GGVL---LANALTGMFSGSHPGEGVG--GGGGEPGGAGEET 194
Dimer_Tnp_hAT pfam05699
hAT family C-terminal dimerization region; This dimerization region is found at the C terminus ...
 650-715 1.76e-04

hAT family C-terminal dimerization region; This dimerization region is found at the C terminus of the transposases of elements belonging to the Activator superfamily (hAT element superfamily). The isolated dimerization region forms extremely stable dimers in vitro.


Pssm-ID: 399013  Cd Length: 83  Bit Score: 40.71  E-value: 1.76e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1320620193 650 DFSTMPVTQFWVKCLQSYPVLSEMVLRLL-LPFpTTYLCETGFSSLLVIKSKYRSRLvvEDDLRCAL 715
Cdd:pfam05699  13 RNEDFDPLEWWKENSSRYPNLSKLARDILsIPV-SSAASERSFSTLGKVILESRNRL--EPLNVEAL 76
DUF2076 pfam09849
Uncharacterized protein conserved in bacteria (DUF2076); This domain, found in various ...
 23-74 8.42e-03

Uncharacterized protein conserved in bacteria (DUF2076); This domain, found in various hypothetical prokaryotic proteins, has no known function. The domain, however, is found in various periplasmic ligand-binding sensor proteins.


Pssm-ID: 430876  Cd Length: 263  Bit Score: 38.57  E-value: 8.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1320620193  23 GSPAAAPRQP-------GLMAQMATTAAGVAVGSavghTLGHAITGGFSGGGSAEPAKP 74
Cdd:pfam09849 140 GQPAQPPRGPwgpggggGFLGGALQTAAGVAGGV----LLAQGIESLFSGGHGGFGGGG 194
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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