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Conserved domains on  [gi|1271360251|ref|NP_001344394|]
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transmembrane prolyl 4-hydroxylase isoform 2 [Mus musculus]

Protein Classification

prolyl 4-hydroxylase family protein( domain architecture ID 707142)

prolyl 4-hydroxylase family protein belongs to the 2-oxoglutarate (2OG)-Fe(II) oxygenase superfamily, and may catalyze the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in proline-rich peptide sequences

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00052 super family cl28127
prolyl 4-hydroxylase; Provisional
 136-216 4.93e-05

prolyl 4-hydroxylase; Provisional


The actual alignment was detected with superfamily member PLN00052:

Pssm-ID: 177683 [Multi-domain]  Cd Length: 310  Bit Score: 43.12  E-value: 4.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1271360251 136 IRTLSLKPLLFEIPGFLSDEECRLIIHLAQMKgLQRSQILPTEEYEEAMSAMQVSQlDLFqlLDQNHD---GRLQLREQV 212
Cdd:PLN00052   47 VKAVSWQPRIFVYKGFLSDAECDHLVKLAKKK-IQRSMVADNKSGKSVMSEVRTSS-GMF--LDKRQDpvvSRIEERIAA 122


                  ....
gi 1271360251 213 WGWI 216
Cdd:PLN00052  123 WTFL 126
 
Name Accession Description Interval E-value
PLN00052 PLN00052
prolyl 4-hydroxylase; Provisional
 136-216 4.93e-05

prolyl 4-hydroxylase; Provisional


Pssm-ID: 177683 [Multi-domain]  Cd Length: 310  Bit Score: 43.12  E-value: 4.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1271360251 136 IRTLSLKPLLFEIPGFLSDEECRLIIHLAQMKgLQRSQILPTEEYEEAMSAMQVSQlDLFqlLDQNHD---GRLQLREQV 212
Cdd:PLN00052   47 VKAVSWQPRIFVYKGFLSDAECDHLVKLAKKK-IQRSMVADNKSGKSVMSEVRTSS-GMF--LDKRQDpvvSRIEERIAA 122


                  ....
gi 1271360251 213 WGWI 216
Cdd:PLN00052  123 WTFL 126
 
Name Accession Description Interval E-value
PLN00052 PLN00052
prolyl 4-hydroxylase; Provisional
 136-216 4.93e-05

prolyl 4-hydroxylase; Provisional


Pssm-ID: 177683 [Multi-domain]  Cd Length: 310  Bit Score: 43.12  E-value: 4.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1271360251 136 IRTLSLKPLLFEIPGFLSDEECRLIIHLAQMKgLQRSQILPTEEYEEAMSAMQVSQlDLFqlLDQNHD---GRLQLREQV 212
Cdd:PLN00052   47 VKAVSWQPRIFVYKGFLSDAECDHLVKLAKKK-IQRSMVADNKSGKSVMSEVRTSS-GMF--LDKRQDpvvSRIEERIAA 122


                  ....
gi 1271360251 213 WGWI 216
Cdd:PLN00052  123 WTFL 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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