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Conserved domains on  [gi|1270111389|ref|NP_001344286.1|]
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tetratricopeptide repeat protein 13 isoform 3 precursor [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11419012)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
134-285 1.33e-29

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 117.80  E-value: 1.33e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 134 IAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFD 212
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYeEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1270111389 213 AATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKA 285
Cdd:COG0457    94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALEL 166
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
134-285 1.33e-29

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 117.80  E-value: 1.33e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 134 IAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFD 212
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYeEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1270111389 213 AATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKA 285
Cdd:COG0457    94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALEL 166
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 129-310 2.29e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.42  E-value: 2.29e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 129 NEELAIAYVLVG-----SGLYDEAIRHFSTMLQEEPDLVSAIYGRG-IAYGKKGLHEAIEAFKEALKQKVDFIDAYKSLG 202
Cdd:TIGR02917 121 DEGAAELLALRGlaylgLGQLELAQKSYEQALAIDPRSLYAKLGLAqLALAENRFDEARALIDEVLTADPGNVDALLLKG 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 203 QAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEG 282
Cdd:TIGR02917 201 DLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDA 280

                         170       180
                  ....*....|....*....|....*...
gi 1270111389 283 IKAQTKVMlndplpgqKASPEYLRVKYL 310
Cdd:TIGR02917 281 RETLQDAL--------KSAPEYLPALLL 300
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 196-282 1.19e-08

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 57.25  E-value: 1.19e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 196 DAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKglshva 275
Cdd:cd24142     1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEKYLY------ 74


                  ....*..
gi 1270111389 276 MGQFYEG 282
Cdd:cd24142    75 LGQLSGG 81
PRK11189 PRK11189
lipoprotein NlpI; Provisional
 166-260 9.37e-08

lipoprotein NlpI; Provisional


Pssm-ID: 236875 [Multi-domain]  Cd Length: 296  Bit Score: 54.51  E-value: 9.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 166 YGRGIAYGKKGLheAIEA---FKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHH 242
Cdd:PRK11189   68 YERGVLYDSLGL--RALArndFSQALALRPDMADAYNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAYLNRGIALYYG 145

                          90
                  ....*....|....*...
gi 1270111389 243 GSLQEALKNFKRCLQLEP 260
Cdd:PRK11189  146 GRYELAQDDLLAFYQDDP 163
TPR_1 pfam00515
Tetratricopeptide repeat;
195-228 1.13e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 45.49  E-value: 1.13e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1270111389 195 IDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 228
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 195-228 1.98e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 44.74  E-value: 1.98e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1270111389  195 IDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 228
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
134-285 1.33e-29

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 117.80  E-value: 1.33e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 134 IAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFD 212
Cdd:COG0457    14 LGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYeEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1270111389 213 AATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKA 285
Cdd:COG0457    94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALEL 166
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
155-294 4.77e-26

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 107.40  E-value: 4.77e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 155 LQEEPDLVSAIYGRGIAYGKKG-LHEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQ 233
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGrYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1270111389 234 LRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 294
Cdd:COG0457    81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDP 141
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
133-329 5.48e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 98.54  E-value: 5.48e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 133 AIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNF 211
Cdd:COG0457    47 NLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYeEALEDYDKALELDPDDAEALYNLGLALLELGRY 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 212 DAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVML 291
Cdd:COG0457   127 DEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1270111389 292 NDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYN 329
Cdd:COG0457   207 LRKKLAILTLAALAELLLLALALLLALRLAALALYQYR 244
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 104-294 1.10e-22

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 103.15  E-value: 1.10e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 104 EKILSQAKSIAEQKRFPFATDNDSTNEELAIAYvLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-EAIE 182
Cdd:COG3914    55 AAAALLALAAGEAAAAAAALLLLAALLELAALL-LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLeEALA 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 183 AFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYN 262
Cdd:COG3914   134 ALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDN 213

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1270111389 263 EV--CQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 294
Cdd:COG3914   214 ADahSNLLFALRQACDWEVYDRFEELLAALARGP 247
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 130-260 1.48e-21

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 91.41  E-value: 1.48e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 130 EELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKG-LHEAIEAFKEALKQKVDFIDAYKSLGQAYREL 208
Cdd:COG4783     6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGdLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1270111389 209 GNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 260
Cdd:COG4783    86 GDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 124-294 2.24e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.80  E-value: 2.24e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 124 DNDSTNEELAIAYVLvgSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKG-LHEAIEAFKEALKQKVDFIDAYKSLG 202
Cdd:COG2956    74 DRAEALLELAQDYLK--AGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGdWEKAIEVLERLLKLGPENAHAYCELA 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 203 QAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEG 282
Cdd:COG2956   152 ELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEA 231

                         170
                  ....*....|..
gi 1270111389 283 IKAQTKVMLNDP 294
Cdd:COG2956   232 LELLRKALELDP 243
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 146-260 1.48e-19

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 85.06  E-value: 1.48e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 146 EAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLL 224
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYdEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1270111389 225 NQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 260
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 134-320 1.69e-19

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 93.13  E-value: 1.69e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 134 IAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFD 212
Cdd:COG3914   118 LGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLeEAIAALRRALELDPDNAEALNNLGNALQDLGRLE 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 213 AATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVC-----QYMKGLS-------HVAMGQFY 280
Cdd:COG3914   198 EAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELspfalLYLPDDDpaellalARAWAQLV 277

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1270111389 281 E-GIKAQTKVMLNDPLPGQKaspeyLRVKYLreySRYLHAH 320
Cdd:COG3914   278 AaAAAPELPPPPNPRDPDRK-----LRIGYV---SADFRRH 310
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 131-311 5.42e-19

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 87.86  E-value: 5.42e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 131 ELAIAYVLvgSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHE-AIEAFKEALKQKVDFIDAYKSLGQAYRELG 209
Cdd:COG2956    13 FKGLNYLL--NGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDrAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 210 NFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKV 289
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKA 170

                         170       180
                  ....*....|....*....|..
gi 1270111389 290 MlndplpgqKASPEYLRVKYLR 311
Cdd:COG2956   171 L--------KLDPDCARALLLL 184
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 179-285 2.54e-18

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 81.59  E-value: 2.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 179 EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQL 258
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100
                  ....*....|....*....|....*..
gi 1270111389 259 EPYNEVCQYMKGLSHVAMGQFYEGIKA 285
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAA 107
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 162-294 3.36e-18

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 81.78  E-value: 3.36e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 162 VSAIYGRGIAYGKKG-LHEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLY 240
Cdd:COG4783     4 AEALYALAQALLLAGdYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1270111389 241 HHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 294
Cdd:COG4783    84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
156-260 6.09e-18

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 83.43  E-value: 6.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 156 QEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQL 234
Cdd:COG4785    67 LALPDLAQLYYERGVAYDSLGDYdLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                          90       100
                  ....*....|....*....|....*.
gi 1270111389 235 RGMMLYHHGSLQEALKNFKRCLQLEP 260
Cdd:COG4785   147 RGIALYYLGRYELAIADLEKALELDP 172
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 107-264 2.95e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 82.47  E-value: 2.95e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 107 LSQAKSIAEQkrfpfATDNDSTNEE--LAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKG-LHEAIEA 183
Cdd:COG2956    92 LDRAEELLEK-----LLELDPDDAEalRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGdYDEAIEA 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 184 FKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNE 263
Cdd:COG2956   167 LEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDD 246


                  .
gi 1270111389 264 V 264
Cdd:COG2956   247 L 247
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 137-294 9.78e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.93  E-value: 9.78e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 137 VLVGSGLYDEAIRHfstMLQEEPDlvsaiygrgiaygkkglhEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATE 216
Cdd:COG2956     5 VAAALGWYFKGLNY---LLNGQPD------------------KAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIR 63

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1270111389 217 SFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDP 294
Cdd:COG2956    64 IHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGP 141
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
131-257 8.39e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 77.26  E-value: 8.39e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 131 ELAIAYVLVGsgLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQKVDFIDAYKSLGQAYRELG 209
Cdd:COG4785    78 ERGVAYDSLG--DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYdAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1270111389 210 NFDAATESFQKALLLNQNHVQTLQLRG-------------------MMLY-HHGSLQEALKNFKRCLQ 257
Cdd:COG4785   156 RYELAIADLEKALELDPNDPERALWLYlaerkldpekalallledwATAYlLQGDTEEARELFKLALA 223
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 116-228 1.38e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 74.07  E-value: 1.38e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 116 QKRFPFATDNDSTNEE--LAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKG-LHEAIEAFKEALKQKV 192
Cdd:COG4783    24 EALLEKALELDPDNPEafALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGdYDEALALLEKALKLDP 103

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1270111389 193 DFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 228
Cdd:COG4783   104 EHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 132-260 4.15e-14

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 70.37  E-value: 4.15e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 132 LAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKG-LHEAIEAFKEALKQKVDFIDAYKSLGQAYRELGN 210
Cdd:COG5010    24 VEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGdFEESLALLEQALQLDPNNPELYYNLALLYSRSGD 103

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1270111389 211 FDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 260
Cdd:COG5010   104 KDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 131-257 5.56e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.84  E-value: 5.56e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 131 ELAIAYVlvGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQKVDFIDAYKSLGQAYRELG 209
Cdd:COG2956   149 ELAELYL--EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYeEAIAALERALEQDPDYLPALPRLAELYEKLG 226

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1270111389 210 NFDAATESFQKALLLNQNHVQTLQLrGMMLYHHGSLQEALKNFKRCLQ 257
Cdd:COG2956   227 DPEEALELLRKALELDPSDDLLLAL-ADLLERKEGLEAALALLERQLR 273
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 113-225 7.77e-14

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 69.60  E-value: 7.77e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 113 IAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKG-LHEAIEAFKEALKQK 191
Cdd:COG5010    39 EDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGdKDEAKEYYEKALALS 118

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1270111389 192 VDFIDAYKSLGQAYRELGNFDAATESFQKALLLN 225
Cdd:COG5010   119 PDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 131-238 5.44e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 66.57  E-value: 5.44e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 131 ELAIAYVLvgSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKG-LHEAIEAFKEALKQKVDFIDAYKSLGQAYRELG 209
Cdd:COG4235    22 LLGRAYLR--LGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGdTEEAEELLERALALDPDNPEALYLLGLAAFQQG 99

                          90       100
                  ....*....|....*....|....*....
gi 1270111389 210 NFDAATESFQKALLLNQNHVQTLQLRGMM 238
Cdd:COG4235   100 DYAEAIAAWQKLLALLPADAPARLLEASI 128
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 155-295 7.92e-13

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 66.91  E-value: 7.92e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 155 LQEEPDLVSAIYGRGIAYGKKGLHEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQL 234
Cdd:COG5010    14 LLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYN 93

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1270111389 235 RGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPL 295
Cdd:COG5010    94 LALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
137-225 5.03e-12

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 62.50  E-value: 5.03e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 137 VLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATE 216
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALA 80


                  ....*....
gi 1270111389 217 SFQKALLLN 225
Cdd:COG3063    81 YLERALELD 89
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 129-310 2.29e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.42  E-value: 2.29e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 129 NEELAIAYVLVG-----SGLYDEAIRHFSTMLQEEPDLVSAIYGRG-IAYGKKGLHEAIEAFKEALKQKVDFIDAYKSLG 202
Cdd:TIGR02917 121 DEGAAELLALRGlaylgLGQLELAQKSYEQALAIDPRSLYAKLGLAqLALAENRFDEARALIDEVLTADPGNVDALLLKG 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 203 QAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEG 282
Cdd:TIGR02917 201 DLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDA 280

                         170       180
                  ....*....|....*....|....*...
gi 1270111389 283 IKAQTKVMlndplpgqKASPEYLRVKYL 310
Cdd:TIGR02917 281 RETLQDAL--------KSAPEYLPALLL 300
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
204-294 1.00e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 58.64  E-value: 1.00e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 204 AYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKnFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGI 283
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|.
gi 1270111389 284 KAQTKVMLNDP 294
Cdd:COG3063    80 AYLERALELDP 90
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 104-317 5.52e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 62.79  E-value: 5.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 104 EKILSQAKSIAEQkrfpfatdndSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRG-IAYGKKGLHEAIE 182
Cdd:TIGR02917 145 QKSYEQALAIDPR----------SLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGdLLLSLGNIELALA 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 183 AFKEALKQKVDFIDAYKSLG----------QAYREL------------------------GNFDAATESFQKALLLNQNH 228
Cdd:TIGR02917 215 AYRKAIALRPNNIAVLLALAtilieagefeEAEKHAdallkkapnsplahylkalvdfqkKNYEDARETLQDALKSAPEY 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 229 VQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIkAQTKVML----NDPLPGQKASPEY 304
Cdd:TIGR02917 295 LPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAI-ATLSPALgldpDDPAALSLLGEAY 373

                         250
                  ....*....|...
gi 1270111389 305 LRVKYLREYSRYL 317
Cdd:TIGR02917 374 LALGDFEKAAEYL 386
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
193-306 7.06e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 56.85  E-value: 7.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 193 DFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLS 272
Cdd:COG4785    71 DLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIA 150

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1270111389 273 HVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLR 306
Cdd:COG4785   151 LYYLGRYELAIADLEKALELDPNDPERALWLYLA 184
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 196-282 1.19e-08

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 57.25  E-value: 1.19e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 196 DAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKglshva 275
Cdd:cd24142     1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGYEKYLY------ 74


                  ....*..
gi 1270111389 276 MGQFYEG 282
Cdd:cd24142    75 LGQLSGG 81
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 122-308 1.23e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 58.56  E-value: 1.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 122 ATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAY-GKKGLHEAIEAFKEALKQKVDFIDAYKS 200
Cdd:TIGR02917 425 QLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYlGKGDLAKAREAFEKALSIEPDFFPAAAN 504

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 201 LGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVcqymkglSHVAMGQFY 280
Cdd:TIGR02917 505 LARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIE-------PALALAQYY 577

                         170       180       190
                  ....*....|....*....|....*....|
gi 1270111389 281 EGIK--AQTKVMLNDPLPGQKASPEYLRVK 308
Cdd:TIGR02917 578 LGKGqlKKALAILNEAADAAPDSPEAWLML 607
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 111-294 2.09e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.79  E-value: 2.09e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 111 KSIAEQKRFPfatdndstNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRG-IAYGKKGLHEAIEAFKEALK 189
Cdd:TIGR02917 218 KAIALRPNNI--------AVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKAlVDFQKKNYEDARETLQDALK 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 190 QKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMK 269
Cdd:TIGR02917 290 SAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLL 369

                         170       180
                  ....*....|....*....|....*
gi 1270111389 270 GLSHVAMGQFYEGIKAQTKVMLNDP 294
Cdd:TIGR02917 370 GEAYLALGDFEKAAEYLAKATELDP 394
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 141-222 3.16e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 52.30  E-value: 3.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 141 SGLYDEAIRHFSTMLQEEPD---LVSAIYGRGIAYGKKG-LHEAIEAFKEALKQKVDFI---DAYKSLGQAYRELGNFDA 213
Cdd:COG1729     6 AGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGdYDEAAEAFEKLLKRYPDSPkapDALLKLGLSYLELGDYDK 85


                  ....*....
gi 1270111389 214 ATESFQKAL 222
Cdd:COG1729    86 ARATLEELI 94
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 144-296 3.26e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.02  E-value: 3.26e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 144 YDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHEAIEA-FKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKAL 222
Cdd:TIGR02917 277 YEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQyLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPAL 356

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1270111389 223 LLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKA-QTKVMLNDPLP 296
Cdd:TIGR02917 357 GLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADlETAAQLDPELG 431
PRK11189 PRK11189
lipoprotein NlpI; Provisional
 166-260 9.37e-08

lipoprotein NlpI; Provisional


Pssm-ID: 236875 [Multi-domain]  Cd Length: 296  Bit Score: 54.51  E-value: 9.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 166 YGRGIAYGKKGLheAIEA---FKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHH 242
Cdd:PRK11189   68 YERGVLYDSLGL--RALArndFSQALALRPDMADAYNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAYLNRGIALYYG 145

                          90
                  ....*....|....*...
gi 1270111389 243 GSLQEALKNFKRCLQLEP 260
Cdd:PRK11189  146 GRYELAQDDLLAFYQDDP 163
TPR_1 pfam00515
Tetratricopeptide repeat;
195-228 1.13e-06

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 45.49  E-value: 1.13e-06
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1270111389 195 IDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 228
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 109-260 1.40e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.01  E-value: 1.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 109 QAKSIAEQKRFPFATDNDSTNEELAiAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEA 187
Cdd:TIGR02917 345 VDEAIATLSPALGLDPDDPAALSLL-GEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPsEAIADLETA 423

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111389 188 LKQKVDFIDAYKSLGQAYRELGNFDAATeSFQKALLLNQ-NHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 260
Cdd:TIGR02917 424 AQLDPELGRADLLLILSYLRSGQFDKAL-AAAKKLEKKQpDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEP 496
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 195-228 1.98e-06

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 44.74  E-value: 1.98e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1270111389  195 IDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 228
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 119-257 7.04e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 49.60  E-value: 7.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 119 FPFATDNDSTNEELAIAYVLVGS-----GLYDEAIRHFSTMLQEEPDLV-SAIYGRGIAYGKKGLHEAIEAFKEALKQKV 192
Cdd:TIGR00990 317 FEKALDLGKLGEKEAIALNLRGTfkclkGKHLEALADLSKSIELDPRVTqSYIKRASMNLELGDPDKAEEDFDKALKLNS 396

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111389 193 DFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHV-QTLQLrGMMLYHHGSLQEALKNFKRCLQ 257
Cdd:TIGR00990 397 EDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIfSHIQL-GVTQYKEGSIASSMATFRRCKK 461
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 126-288 8.11e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.31  E-value: 8.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 126 DSTNEELAIAYV--LVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHE-AIEAFKEALKQKVDFIDAYKSLG 202
Cdd:TIGR02917 563 NPQEIEPALALAqyYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNkAVSSFKKLLALQPDSALALLLLA 642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 203 QAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEG 282
Cdd:TIGR02917 643 DAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAA 722


                  ....*.
gi 1270111389 283 IKAQTK 288
Cdd:TIGR02917 723 IQAYRK 728
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 131-222 9.95e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 9.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 131 ELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHEAIEAFKEALKQKVDFIDAYKSLGQAYRELGN 210
Cdd:TIGR02917 773 RTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGE 852

                          90
                  ....*....|..
gi 1270111389 211 FDAATESFQKAL 222
Cdd:TIGR02917 853 ADRALPLLRKAV 864
TPR_12 pfam13424
Tetratricopeptide repeat;
193-258 2.33e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.14  E-value: 2.33e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1270111389 193 DFIDAYKSLGQAYRELGNFDAATESFQKALLLNQ-----NHVQTLQLR---GMMLYHHGSLQEALKNFKRCLQL 258
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARrllgpDHPLTATTLlnlGRLYLELGRYEEALELLERALAL 74
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 129-224 2.33e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 47.21  E-value: 2.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 129 NEELAIAYVLVGSGLYDEAIRHFSTMLQEEPD---LVSAIyGRgIAYGKKGLHEAIEAFKEALKQKVDfIDAYKSLGQAY 205
Cdd:COG3071   225 DPRLVRLYGRLQGGDPAKQLKRAEKWLKKHPNdpdLLLAL-GR-LCLRNQLWGKAREYLEAALALRPS-AEAYAELARLL 301

                          90
                  ....*....|....*....
gi 1270111389 206 RELGNFDAATESFQKALLL 224
Cdd:COG3071   302 EQLGDPEEAAEHYRKALAL 320
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 179-260 2.93e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 43.83  E-value: 2.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 179 EAIEAFKEALKQKVD---FIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQT---LQLRGMMLYHHGSLQEALKNF 252
Cdd:COG1729    11 EAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKARATL 90


                  ....*...
gi 1270111389 253 KRCLQLEP 260
Cdd:COG1729    91 EELIKKYP 98
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 145-284 3.89e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 3.89e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 145 DEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKG-LHEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALL 223
Cdd:TIGR02917 516 DDAIQRFEKVLTIDPKNLRAILALAGLYLRTGnEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAAD 595

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1270111389 224 LNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNevcqymkGLSHVAMGQFYEGIK 284
Cdd:TIGR02917 596 AAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDS-------ALALLLLADAYAVMK 649
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 128-260 4.60e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 46.06  E-value: 4.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 128 TNEELAIAYV--LVGSGLYDEAIRHFSTMLQEEPD--LVSAiYGRGIAygkKGLHEAIEAFKEALKQKVDFIDAYKSLGQ 203
Cdd:COG3071   191 RDPELAAAYAraLIALGDHDEAERLLREALKRQWDprLVRL-YGRLQG---GDPAKQLKRAEKWLKKHPNDPDLLLALGR 266

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111389 204 AYRELGNFDAATESFQKALLLNQNhVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEP 260
Cdd:COG3071   267 LCLRNQLWGKAREYLEAALALRPS-AEAYAELARLLEQLGDPEEAAEHYRKALALAL 322
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 114-295 1.32e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.46  E-value: 1.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 114 AEQKRFPFATDN------DSTNEELAI--AYVLVGSGLYDEAIRHFSTMLQEEP-DLVSAIYGRGIAYGKKGLHEAIEAF 184
Cdd:TIGR02917 714 LRQKDYPAAIQAyrkalkRAPSSQNAIklHRALLASGNTAEAVKTLEAWLKTHPnDAVLRTALAELYLAQKDYDKAIKHY 793

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 185 KEALKQKVDFIDAYKSLGQAYRELGNfDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEV 264
Cdd:TIGR02917 794 QTVVKKAPDNAVVLNNLAWLYLELKD-PRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAA 872

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1270111389 265 CQYmkglsHVAMGQFYEGIKAQTKVMLNDPL 295
Cdd:TIGR02917 873 IRY-----HLALALLATGRKAEARKELDKLL 898
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 144-284 1.67e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 44.97  E-value: 1.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 144 YDEAIRHFSTMLQE---EPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQ 219
Cdd:TIGR00990 310 YEEAARAFEKALDLgklGEKEAIALNLRGTFKCLKGKHlEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFD 389

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111389 220 KALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYN-------EVCQYMKGLSHVAMGQFYEGIK 284
Cdd:TIGR00990 390 KALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFifshiqlGVTQYKEGSIASSMATFRRCKK 461
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 196-227 3.16e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 38.66  E-value: 3.16e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1270111389 196 DAYKSLGQAYRELGNFDAATESFQKALLLNQN 227
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_12 pfam13424
Tetratricopeptide repeat;
160-222 4.54e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.29  E-value: 4.54e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1270111389 160 DLVSAIYGRGIAYGKKGLH-EAIEAFKEALK--QKVDFID------AYKSLGQAYRELGNFDAATESFQKAL 222
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYdEALELLEKALEiaRRLLGPDhpltatTLLNLGRLYLELGRYEEALELLERAL 72
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 122-329 8.25e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.76  E-value: 8.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 122 ATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHEAIEA-FKEALKQKVDFIDAYKS 200
Cdd:TIGR02917  16 ACGDQSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKeLRKALSLGYPKNQVLPL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 201 LGQAYRELGNFDAATESFQKALLL-NQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQF 279
Cdd:TIGR02917  96 LARAYLLQGKFQQVLDELPGKTLLdDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRF 175

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111389 280 YEGIKAQTKVMLNDPLPGQ----KASPEYLRVKY---LREYSRYLHAHLDTPLTEYN 329
Cdd:TIGR02917 176 DEARALIDEVLTADPGNVDalllKGDLLLSLGNIelaLAAYRKAIALRPNNIAVLLA 232
TPR_19 pfam14559
Tetratricopeptide repeat;
179-235 1.08e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.95  E-value: 1.08e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1270111389 179 EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLR 235
Cdd:pfam14559   6 EALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALL 62
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
177-279 1.13e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.05  E-value: 1.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 177 LHEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLlNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCL 256
Cdd:COG4785    22 AAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALA-LPDLAQLYYERGVAYDSLGDYDLAIADFDQAL 100

                          90       100
                  ....*....|....*....|...
gi 1270111389 257 QLEPYNEVCQYMKGLSHVAMGQF 279
Cdd:COG4785   101 ELDPDLAEAYNNRGLAYLLLGDY 123
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 201-263 1.46e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 37.70  E-value: 1.46e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1270111389 201 LGQAYRELGNFDAATESFQKALLLNQNHVQTLQ---LRGMMLYHHGSLQEALKNFKRCLQLEPYNE 263
Cdd:pfam13432   3 LARAALRAGDYDDAAAALEAALARFPESPDAAAallLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
YfgM COG2976
Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal ...
 132-234 1.79e-03

Putative negative regulator of RcsB-dependent stress response, UPF0070 family [Signal transduction mechanisms];


Pssm-ID: 442215 [Multi-domain]  Cd Length: 207  Bit Score: 40.22  E-value: 1.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 132 LAIAYVLVGSGLYDEAIRHFSTMLQ--EEPDLVSAIYGRgIAygkkGLHEAIEAFKEALKQ-KVDFIDAYKSL-----GQ 203
Cdd:COG2976    94 LLLAKAAVDAGDLDKAAAQLQWVLDnaKDPALKALARLR-LA----RVLLAQKKYDEALATlDAVKPEAFAALyaelrGD 168

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1270111389 204 AYRELGNFDAATESFQKALLLNQNHVQTLQL 234
Cdd:COG2976   169 ILLAQGDKAEARAAYQKALAALPEDAPLRQL 199
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 107-271 1.96e-03

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 41.61  E-value: 1.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389  107 LSQAKSIAEQKRfpfATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIygRGIA--YGKKGLHEAiEAF 184
Cdd:PRK11447   367 LAQAERLYQQAR---QVDNTDSYAVLGLGDVAMARKDYAAAERYYQQALRMDPGNTNAV--RGLAnlYRQQSPEKA-LAF 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389  185 KEAL--KQKVDFIDAYKSL--------GQAYRELGNFDAATESFQKALLLNQNHVQ-TLQLRGmMLYHHGSLQEALKNFK 253
Cdd:PRK11447   441 IASLsaSQRRSIDDIERSLqndrlaqqAEALENQGKWAQAAELQRQRLALDPGSVWlTYRLAQ-DLRQAGQRSQADALMR 519

                          170
                   ....*....|....*...
gi 1270111389  254 RCLQLEPYNEVCQYMKGL 271
Cdd:PRK11447   520 RLAQQKPNDPEQVYAYGL 537
TPR_11 pfam13414
TPR repeat;
169-209 2.40e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.30  E-value: 2.40e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 1270111389 169 GIAYGKKG-LHEAIEAFKEALKQKVDFIDAYKSLGQAYRELG 209
Cdd:pfam13414   1 GDAYYEQGkYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 132-190 2.46e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 36.93  E-value: 2.46e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1270111389 132 LAIAYVLVGSGLYDEAIRHFSTML---QEEPDLVSAIYGRGIAYGKKGLH-EAIEAFKEALKQ 190
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALarfPESPDAAAALLLLGLAALRQGRLaEAAAAYRAALRA 63
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 166-222 3.68e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 36.55  E-value: 3.68e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1270111389 166 YGRGIAYGKKG-LHEAIEAFKEALKQKVDF---IDAYKSLGQAYRELGNFDAATESFQKAL 222
Cdd:pfam13432   1 LALARAALRAGdYDDAAAALEAALARFPESpdaAAALLLLGLAALRQGRLAEAAAAYRAAL 61
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 179-228 4.21e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.92  E-value: 4.21e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1270111389 179 EAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNH 228
Cdd:cd24142    18 LALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG 67
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 102-294 4.89e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 4.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 102 NTEKILSQAKSIAEQKRfpfatDNDSTNEELAIAYVLVGSGlyDEAIRHFSTMLQEEPD------LVSAIYGRgiaygKK 175
Cdd:TIGR02917 582 QLKKALAILNEAADAAP-----DSPEAWLMLGRAQLAAGDL--NKAVSSFKKLLALQPDsalallLLADAYAV-----MK 649

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 176 GLHEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRC 255
Cdd:TIGR02917 650 NYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKA 729

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1270111389 256 LQLEPYNEVCQYMkGLSHVAMGQFYEGIKAQTKVMLNDP 294
Cdd:TIGR02917 730 LKRAPSSQNAIKL-HRALLASGNTAEAVKTLEAWLKTHP 767
TPR_8 pfam13181
Tetratricopeptide repeat;
201-227 5.15e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 35.07  E-value: 5.15e-03
                          10        20
                  ....*....|....*....|....*..
gi 1270111389 201 LGQAYRELGNFDAATESFQKALLLNQN 227
Cdd:pfam13181   7 LGLIYLKLGDYEEAKEYYEKALELDPD 33
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 179-286 7.75e-03

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 39.22  E-value: 7.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 179 EAIEAFKEALKQ--KVDF---IDAYKSLGQAYRELGNFDAATESFQKA--LLLNQNH-----VQTLQLrGMMLYHHGSLQ 246
Cdd:pfam17874  19 RALELAEQALALlpEDDLlarGLATFVLGEAYLCLGDLDAALQAMREAeaLARRADSphvtlWALLQQ-GEILRAQGRLH 97

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1270111389 247 EALKNFKRCLQLEPynevcqyMKGLSHVAMGQFYEGIKAQ 286
Cdd:pfam17874  98 QALETYQQALQLAR-------DHGLQHLPLHGFLLVGLAD 130
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 186-294 9.23e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.63  E-value: 9.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1270111389 186 EALKQKVDFIDAYKSLGQAYRELGNFDAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVC 265
Cdd:COG5010    11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPEL 90

                          90       100
                  ....*....|....*....|....*....
gi 1270111389 266 QYMKGLSHVAMGQFYEGIKAQTKVMLNDP 294
Cdd:COG5010    91 YYNLALLYSRSGDKDEAKEYYEKALALSP 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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