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Conserved domains on  [gi|1254051220|ref|NP_001343582|]
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Serpentine Receptor, class Z [Caenorhabditis elegans]

Protein Classification

class Z serpentine receptor( domain architecture ID 10563420)

class Z serpentine receptor (Srz) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srz pfam10325
Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis ...
 52-303 3.14e-73

Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srz is a solo families amongst the superfamilies of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'. The genes encoding Srz appear to be under strong adaptive evolutionary pressure.


:

Pssm-ID: 431214  Cd Length: 264  Bit Score: 227.47  E-value: 3.14e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254051220  52 FLIVAYFVFLPFYVYVNKVNRRRDEKMIIFPITNHFYKMVMISVIFLIFYTALSTLVEHGNLKEGNILAIIGFMILTVFY 131
Cdd:pfam10325   6 ILLIIYLLIFPFYVYVFKLNRERDKKTLLFPITNHFYKMVKISYFLFIFLIVILILIFFFSSKNSIIGFIFLLLIFLILY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254051220 132 TICMSIQVFQLFIVALAIERFLLYFCPSTEKLITLVQNYVHQRIKCIYISCAIKDLVIFILPYSSDPE------VKMITY 205
Cdd:pfam10325  86 ILYIITQVFHLLIFLLAIQRFLIYFFPSTEKYVLISQKYLHKYIWILYLVFVLKDLILFLLYVITFSKslgwetIKYVYL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254051220 206 AMHYSMEILIILSSLLYLPIMISVRKLSHLASAEQNHPQRYIFWQTMVVLIFKSLTLPASAIALTNDG-TLTETQNAQMN 284
Cdd:pfam10325 166 IIFIILNILLFLSALLYIPIMISIRKLSHLASAQLNKPQKYIFWQTITVLIFKSIYIPLFIFIFLIDFlSEFLIFSIISI 245

                         250
                  ....*....|....*....
gi 1254051220 285 IEIFTIPLIIMLSYLGCNK 303
Cdd:pfam10325 246 TDILTTPLIIQLSYLGCNK 264
 
Name Accession Description Interval E-value
7TM_GPCR_Srz pfam10325
Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis ...
 52-303 3.14e-73

Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srz is a solo families amongst the superfamilies of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'. The genes encoding Srz appear to be under strong adaptive evolutionary pressure.


Pssm-ID: 431214  Cd Length: 264  Bit Score: 227.47  E-value: 3.14e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254051220  52 FLIVAYFVFLPFYVYVNKVNRRRDEKMIIFPITNHFYKMVMISVIFLIFYTALSTLVEHGNLKEGNILAIIGFMILTVFY 131
Cdd:pfam10325   6 ILLIIYLLIFPFYVYVFKLNRERDKKTLLFPITNHFYKMVKISYFLFIFLIVILILIFFFSSKNSIIGFIFLLLIFLILY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254051220 132 TICMSIQVFQLFIVALAIERFLLYFCPSTEKLITLVQNYVHQRIKCIYISCAIKDLVIFILPYSSDPE------VKMITY 205
Cdd:pfam10325  86 ILYIITQVFHLLIFLLAIQRFLIYFFPSTEKYVLISQKYLHKYIWILYLVFVLKDLILFLLYVITFSKslgwetIKYVYL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254051220 206 AMHYSMEILIILSSLLYLPIMISVRKLSHLASAEQNHPQRYIFWQTMVVLIFKSLTLPASAIALTNDG-TLTETQNAQMN 284
Cdd:pfam10325 166 IIFIILNILLFLSALLYIPIMISIRKLSHLASAQLNKPQKYIFWQTITVLIFKSIYIPLFIFIFLIDFlSEFLIFSIISI 245

                         250
                  ....*....|....*....
gi 1254051220 285 IEIFTIPLIIMLSYLGCNK 303
Cdd:pfam10325 246 TDILTTPLIIQLSYLGCNK 264
 
Name Accession Description Interval E-value
7TM_GPCR_Srz pfam10325
Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis ...
 52-303 3.14e-73

Serpentine type 7TM GPCR chemoreceptor Srz; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srz is a solo families amongst the superfamilies of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'. The genes encoding Srz appear to be under strong adaptive evolutionary pressure.


Pssm-ID: 431214  Cd Length: 264  Bit Score: 227.47  E-value: 3.14e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254051220  52 FLIVAYFVFLPFYVYVNKVNRRRDEKMIIFPITNHFYKMVMISVIFLIFYTALSTLVEHGNLKEGNILAIIGFMILTVFY 131
Cdd:pfam10325   6 ILLIIYLLIFPFYVYVFKLNRERDKKTLLFPITNHFYKMVKISYFLFIFLIVILILIFFFSSKNSIIGFIFLLLIFLILY 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254051220 132 TICMSIQVFQLFIVALAIERFLLYFCPSTEKLITLVQNYVHQRIKCIYISCAIKDLVIFILPYSSDPE------VKMITY 205
Cdd:pfam10325  86 ILYIITQVFHLLIFLLAIQRFLIYFFPSTEKYVLISQKYLHKYIWILYLVFVLKDLILFLLYVITFSKslgwetIKYVYL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1254051220 206 AMHYSMEILIILSSLLYLPIMISVRKLSHLASAEQNHPQRYIFWQTMVVLIFKSLTLPASAIALTNDG-TLTETQNAQMN 284
Cdd:pfam10325 166 IIFIILNILLFLSALLYIPIMISIRKLSHLASAQLNKPQKYIFWQTITVLIFKSIYIPLFIFIFLIDFlSEFLIFSIISI 245

                         250
                  ....*....|....*....
gi 1254051220 285 IEIFTIPLIIMLSYLGCNK 303
Cdd:pfam10325 246 TDILTTPLIIQLSYLGCNK 264
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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