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Conserved domains on  [gi|1192786239|ref|NP_001338535|]
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integrator complex subunit 6-like isoform 6 [Homo sapiens]

Protein Classification

integrator subunit 6 family protein( domain architecture ID 10633864)

integrator subunit 6 family protein similar to integrator complex subunit 6 (INTS6) is a component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
INT_SG_DDX_CT_C pfam15300
INTS6/SAGE1/DDX26B/CT45 C-terminus; This domain is found at the C-terminus of integrator ...
534-595 3.89e-33

INTS6/SAGE1/DDX26B/CT45 C-terminus; This domain is found at the C-terminus of integrator complex subunit 6 (INTS6), sarcoma antigen 1 (SAGE1), protein DDX26B (DDX26B) and members of the cancer/testis antigen family 45.


:

Pssm-ID: 464626  Cd Length: 62  Bit Score: 121.06  E-value: 3.89e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1192786239 534 GINADIKHQLMKEVRKFGRKYERIFILLEEVQGPLEMKKQFVEFTIKEAARFKRRVLIQYLE 595
Cdd:pfam15300   1 EHNAELKKQVFKEIRRPGRNYEKIFKLLEQVQGPLEIRKKFVEDVIKEAARFKRRVLIQQLE 62
 
Name Accession Description Interval E-value
INT_SG_DDX_CT_C pfam15300
INTS6/SAGE1/DDX26B/CT45 C-terminus; This domain is found at the C-terminus of integrator ...
534-595 3.89e-33

INTS6/SAGE1/DDX26B/CT45 C-terminus; This domain is found at the C-terminus of integrator complex subunit 6 (INTS6), sarcoma antigen 1 (SAGE1), protein DDX26B (DDX26B) and members of the cancer/testis antigen family 45.


Pssm-ID: 464626  Cd Length: 62  Bit Score: 121.06  E-value: 3.89e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1192786239 534 GINADIKHQLMKEVRKFGRKYERIFILLEEVQGPLEMKKQFVEFTIKEAARFKRRVLIQYLE 595
Cdd:pfam15300   1 EHNAELKKQVFKEIRRPGRNYEKIFKLLEQVQGPLEIRKKFVEDVIKEAARFKRRVLIQQLE 62
 
Name Accession Description Interval E-value
INT_SG_DDX_CT_C pfam15300
INTS6/SAGE1/DDX26B/CT45 C-terminus; This domain is found at the C-terminus of integrator ...
534-595 3.89e-33

INTS6/SAGE1/DDX26B/CT45 C-terminus; This domain is found at the C-terminus of integrator complex subunit 6 (INTS6), sarcoma antigen 1 (SAGE1), protein DDX26B (DDX26B) and members of the cancer/testis antigen family 45.


Pssm-ID: 464626  Cd Length: 62  Bit Score: 121.06  E-value: 3.89e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1192786239 534 GINADIKHQLMKEVRKFGRKYERIFILLEEVQGPLEMKKQFVEFTIKEAARFKRRVLIQYLE 595
Cdd:pfam15300   1 EHNAELKKQVFKEIRRPGRNYEKIFKLLEQVQGPLEIRKKFVEDVIKEAARFKRRVLIQQLE 62
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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