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Conserved domains on  [gi|1189438295|ref|NP_001338208|]
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transmembrane protein 107 isoform 4 [Homo sapiens]

Protein Classification

transmembrane protein 107( domain architecture ID 10633196)

transmembrane protein 107 (TMEM107) plays a role in cilia formation and embryonic patterning

PubMed:  26518474|26595381

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TMEM107 pfam14995
Transmembrane protein; This family of proteins is found in eukaryotes. Proteins in this family ...
 7-122 2.91e-41

Transmembrane protein; This family of proteins is found in eukaryotes. Proteins in this family are typically between 138 and 164 amino acids in length. There are two completely conserved residues (H and E) that may be functionally important and four transmembrane helices. The domains in this family vary in length from 124 to 126 amino acids. The precise function of the protein family is still unknown.


:

Pssm-ID: 464430  Cd Length: 123  Bit Score: 133.14  E-value: 2.91e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438295   7 LVPSRFLTLLAHLVVVITLFWSRDSNIQACLPLTFTPEEYDKQDIQLVAALSVTLGLFAVELAGFLSGVSMFNSTQSLIS 86
Cdd:pfam14995   1 LIPARFLTLIAHLIILITILWSRDENVLACLPLDFTESEYSTEDTSLVVALSLSLLCLVIEFIGFFSGISMFSDTQSLLS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1189438295  87 IGAHCSASVALSFFIFERWECTTY-------CALPAVTEMALF 122
Cdd:pfam14995  81 ICLHAIAAILLSFFIFEQWPCDSYwyvfaffSVLPALLELLAL 123
 
Name Accession Description Interval E-value
TMEM107 pfam14995
Transmembrane protein; This family of proteins is found in eukaryotes. Proteins in this family ...
 7-122 2.91e-41

Transmembrane protein; This family of proteins is found in eukaryotes. Proteins in this family are typically between 138 and 164 amino acids in length. There are two completely conserved residues (H and E) that may be functionally important and four transmembrane helices. The domains in this family vary in length from 124 to 126 amino acids. The precise function of the protein family is still unknown.


Pssm-ID: 464430  Cd Length: 123  Bit Score: 133.14  E-value: 2.91e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438295   7 LVPSRFLTLLAHLVVVITLFWSRDSNIQACLPLTFTPEEYDKQDIQLVAALSVTLGLFAVELAGFLSGVSMFNSTQSLIS 86
Cdd:pfam14995   1 LIPARFLTLIAHLIILITILWSRDENVLACLPLDFTESEYSTEDTSLVVALSLSLLCLVIEFIGFFSGISMFSDTQSLLS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1189438295  87 IGAHCSASVALSFFIFERWECTTY-------CALPAVTEMALF 122
Cdd:pfam14995  81 ICLHAIAAILLSFFIFEQWPCDSYwyvfaffSVLPALLELLAL 123
 
Name Accession Description Interval E-value
TMEM107 pfam14995
Transmembrane protein; This family of proteins is found in eukaryotes. Proteins in this family ...
 7-122 2.91e-41

Transmembrane protein; This family of proteins is found in eukaryotes. Proteins in this family are typically between 138 and 164 amino acids in length. There are two completely conserved residues (H and E) that may be functionally important and four transmembrane helices. The domains in this family vary in length from 124 to 126 amino acids. The precise function of the protein family is still unknown.


Pssm-ID: 464430  Cd Length: 123  Bit Score: 133.14  E-value: 2.91e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1189438295   7 LVPSRFLTLLAHLVVVITLFWSRDSNIQACLPLTFTPEEYDKQDIQLVAALSVTLGLFAVELAGFLSGVSMFNSTQSLIS 86
Cdd:pfam14995   1 LIPARFLTLIAHLIILITILWSRDENVLACLPLDFTESEYSTEDTSLVVALSLSLLCLVIEFIGFFSGISMFSDTQSLLS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1189438295  87 IGAHCSASVALSFFIFERWECTTY-------CALPAVTEMALF 122
Cdd:pfam14995  81 ICLHAIAAILLSFFIFEQWPCDSYwyvfaffSVLPALLELLAL 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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