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Conserved domains on  [gi|1143474957|ref|NP_001335575|]
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Protein lev-9 [Caenorhabditis elegans]

Protein Classification

beta-2-glycoprotein 1( domain architecture ID 12867676)

beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
127-363 2.94e-25

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 105.51  E-value: 2.94e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 127 PPEIPFAVHDGSSFSGEYDLDAEVAYNCIPGYHKfNAKGLSISKCLLNRKNVAQwfgpdlRCKARACPDPGDIENGLREG 206
Cdd:PHA02927   27 PINMKFKNSVETDANANYNIGDTIEYLCLPGYRK-QKMGPIYAKCTGTGWTLFN------QCIKRRCPSPRDIDNGQLDI 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 207 DTFEYPHHVKYSCNPGFLLVGSTSRQCS--SNGE--WTNEPANCKATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHG 280
Cdd:PHA02927  100 GGVDFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTdgSVVTYSCNSG 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 281 YRLVGQVQRIClAEGIWgGNEPRCEEIRCSvLPTLPNGYIEGS---ETSFGAVAVFRCLETMTHEGASKAKCMEDGQWSA 357
Cdd:PHA02927  180 YSLIGNSGVLC-SGGEW-SDPPTCQIVKCP-HPTISNGYLSSGfkrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQP 256

                  ....*.
gi 1143474957 358 PIPRCL 363
Cdd:PHA02927  257 ELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
64-119 5.53e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 5.53e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1143474957  64 CHPLPNIENGFIRTA-GDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVCR 119
Cdd:cd00033     1 CPPPPVPENGTVTGSkGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
377-557 2.91e-09

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.13  E-value: 2.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 377 RDKSEGQL----IASGSKVIVECNKQHEANIDERLICS-NSTWSHV-----PVCSPLSCHNwPPRVPHARILFSKS--SH 444
Cdd:PHA02927   90 RDIDNGQLdiggVDFGSSITYSCNSGYQLIGESKSYCElGSTGSMVwnpeaPICESVKCQS-PPSISNGRHNGYEDfyTD 168
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 445 GSIAKYECNNGYHPNRNNQIIkCLYGEWTKdgpPMKCLPSWCEHPSKTYGTLPGGqillegilgayefqsYIQKVEEGRA 524
Cdd:PHA02927  169 GSVVTYSCNSGYSLIGNSGVL-CSGGEWSD---PPTCQIVKCPHPTISNGYLSSG---------------FKRSYSYNDN 229
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1143474957 525 ISFQCGKGNYLIGPPKATCVNGE-WMPKVsPKCV 557
Cdd:PHA02927  230 VDFKCKYGYKLSGSSSSTCSPGNtWQPEL-PKCV 262
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
127-363 2.94e-25

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 105.51  E-value: 2.94e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 127 PPEIPFAVHDGSSFSGEYDLDAEVAYNCIPGYHKfNAKGLSISKCLLNRKNVAQwfgpdlRCKARACPDPGDIENGLREG 206
Cdd:PHA02927   27 PINMKFKNSVETDANANYNIGDTIEYLCLPGYRK-QKMGPIYAKCTGTGWTLFN------QCIKRRCPSPRDIDNGQLDI 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 207 DTFEYPHHVKYSCNPGFLLVGSTSRQCS--SNGE--WTNEPANCKATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHG 280
Cdd:PHA02927  100 GGVDFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTdgSVVTYSCNSG 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 281 YRLVGQVQRIClAEGIWgGNEPRCEEIRCSvLPTLPNGYIEGS---ETSFGAVAVFRCLETMTHEGASKAKCMEDGQWSA 357
Cdd:PHA02927  180 YSLIGNSGVLC-SGGEW-SDPPTCQIVKCP-HPTISNGYLSSGfkrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQP 256

                  ....*.
gi 1143474957 358 PIPRCL 363
Cdd:PHA02927  257 ELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
193-247 1.02e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 62.87  E-value: 1.02e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1143474957 193 CPDPGDIENGLREGDTFEYPH--HVKYSCNPGFLLVGSTSRQCSSNGEWTNEPANCK 247
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYgsTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
64-119 5.53e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 5.53e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1143474957  64 CHPLPNIENGFIRTA-GDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVCR 119
Cdd:cd00033     1 CPPPPVPENGTVTGSkGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
64-118 1.28e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.85  E-value: 1.28e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957   64 CHPLPNIENGFIR-TAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVC 118
Cdd:smart00032   1 CPPPPDIENGTVTsSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
193-246 6.74e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.92  E-value: 6.74e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957  193 CPDPGDIENGLREGDTFEYPH--HVKYSCNPGFLLVGSTSRQCSSNGEWTNEPANC 246
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYgdTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
377-557 2.91e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.13  E-value: 2.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 377 RDKSEGQL----IASGSKVIVECNKQHEANIDERLICS-NSTWSHV-----PVCSPLSCHNwPPRVPHARILFSKS--SH 444
Cdd:PHA02927   90 RDIDNGQLdiggVDFGSSITYSCNSGYQLIGESKSYCElGSTGSMVwnpeaPICESVKCQS-PPSISNGRHNGYEDfyTD 168
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 445 GSIAKYECNNGYHPNRNNQIIkCLYGEWTKdgpPMKCLPSWCEHPSKTYGTLPGGqillegilgayefqsYIQKVEEGRA 524
Cdd:PHA02927  169 GSVVTYSCNSGYSLIGNSGVL-CSGGEWSD---PPTCQIVKCPHPTISNGYLSSG---------------FKRSYSYNDN 229
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1143474957 525 ISFQCGKGNYLIGPPKATCVNGE-WMPKVsPKCV 557
Cdd:PHA02927  230 VDFKCKYGYKLSGSSSSTCSPGNtWQPEL-PKCV 262
Sushi pfam00084
Sushi repeat (SCR repeat);
309-362 3.15e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.27  E-value: 3.15e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957 309 CSVLPTLPNGYIEGS--ETSFGAVAVFRCLETMTHEGASKAKCMEDGQWSAPIPRC 362
Cdd:pfam00084   1 CPPPPDIPNGKVSATknEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
64-118 1.70e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.70e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957  64 CHPLPNIENGFIR-TAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVC 118
Cdd:pfam00084   1 CPPPPDIPNGKVSaTKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
425-481 1.77e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 39.75  E-value: 1.77e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 425 CHNwPPRVPHARILFSKS--SHGSIAKYECNNGYHPnRNNQIIKCL-YGEWTkdGPPMKC 481
Cdd:cd00033     1 CPP-PPVPENGTVTGSKGsySYGSTVTYSCNEGYTL-VGSSTITCTeNGGWS--PPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
425-481 2.32e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.74  E-value: 2.32e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957  425 CHNwPPRVPHARILFSKS--SHGSIAKYECNNGYHPNRNNqIIKCL-YGEWTkdGPPMKC 481
Cdd:smart00032   1 CPP-PPDIENGTVTSSSGtySYGDTVTYSCDPGYTLIGSS-TITCLeNGTWS--PPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
520-556 8.02e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 35.17  E-value: 8.02e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1143474957 520 EEGRAISFQCGKGNYLIGPPKATCV-NGEWMPKVsPKC 556
Cdd:pfam00084  20 NYGASVSYECDPGYRLVGSPTITCQeDGTWSPPF-PEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
127-363 2.94e-25

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 105.51  E-value: 2.94e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 127 PPEIPFAVHDGSSFSGEYDLDAEVAYNCIPGYHKfNAKGLSISKCLLNRKNVAQwfgpdlRCKARACPDPGDIENGLREG 206
Cdd:PHA02927   27 PINMKFKNSVETDANANYNIGDTIEYLCLPGYRK-QKMGPIYAKCTGTGWTLFN------QCIKRRCPSPRDIDNGQLDI 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 207 DTFEYPHHVKYSCNPGFLLVGSTSRQCS--SNGE--WTNEPANCKATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHG 280
Cdd:PHA02927  100 GGVDFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTdgSVVTYSCNSG 179
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 281 YRLVGQVQRIClAEGIWgGNEPRCEEIRCSvLPTLPNGYIEGS---ETSFGAVAVFRCLETMTHEGASKAKCMEDGQWSA 357
Cdd:PHA02927  180 YSLIGNSGVLC-SGGEW-SDPPTCQIVKCP-HPTISNGYLSSGfkrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQP 256

                  ....*.
gi 1143474957 358 PIPRCL 363
Cdd:PHA02927  257 ELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
66-246 1.71e-16

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 79.70  E-value: 1.71e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957  66 PLP-NIENGFIRTAGdLRFGSNAEYGCNKGYILVGASQRRCQ----ANKEWSSSQPVCRlQLKCGPPPEIPFAVHDGssF 140
Cdd:PHA02927   87 PSPrDIDNGQLDIGG-VDFGSSITYSCNSGYQLIGESKSYCElgstGSMVWNPEAPICE-SVKCQSPPSISNGRHNG--Y 162
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 141 SGEYDLDAEVAYNCIPGYHKFNAKGLSISKcllnrknvAQWFGPDlRCKARACPDPgDIENG-LREG--DTFEYPHHVKY 217
Cdd:PHA02927  163 EDFYTDGSVVTYSCNSGYSLIGNSGVLCSG--------GEWSDPP-TCQIVKCPHP-TISNGyLSSGfkRSYSYNDNVDF 232
                         170       180
                  ....*....|....*....|....*....
gi 1143474957 218 SCNPGFLLVGSTSRQCSSNGEWTNEPANC 246
Cdd:PHA02927  233 KCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
PHA02639 PHA02639
EEV host range protein; Provisional
189-363 9.62e-16

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 78.17  E-value: 9.62e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 189 KARACPDPGDIENGL--REGDTFEYPHHVKYSCNPGFLLVGSTSRQC---SSNGEWTNEPANCKATECSRPSSPLHGKVV 263
Cdd:PHA02639   18 KSIYCDKPDDISNGFitELMEKYEIGKLIEYTCNTDYALIGDRFRTCikdKNNAIWSNKAPFCMLKECNDPPSIINGKIY 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 264 GSSLTYQ--SVVTYSCDH----GYRLVGQVQRICLAEGIWGGNEPRCEEIRCSvLPTLPNGYIEGSETS----FGAVAVF 333
Cdd:PHA02639   98 NKREMYKvgDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKPDPPICKMINCR-FPALQNGYINGIPSNkkfyYKTRVGF 176
                         170       180       190
                  ....*....|....*....|....*....|
gi 1143474957 334 RCLETMTHEGASKAKCMEDGQWSAPIPRCL 363
Cdd:PHA02639  177 SCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
193-247 1.02e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 62.87  E-value: 1.02e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1143474957 193 CPDPGDIENGLREGDTFEYPH--HVKYSCNPGFLLVGSTSRQCSSNGEWTNEPANCK 247
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYgsTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
64-119 5.53e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 5.53e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1143474957  64 CHPLPNIENGFIRTA-GDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVCR 119
Cdd:cd00033     1 CPPPPVPENGTVTGSkGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
64-118 1.28e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.85  E-value: 1.28e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957   64 CHPLPNIENGFIR-TAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVC 118
Cdd:smart00032   1 CPPPPDIENGTVTsSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
251-305 1.50e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 59.78  E-value: 1.50e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1143474957 251 CSRPSSPLHGKVVGSSLTY--QSVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRCE 305
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYsyGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
205-363 1.73e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 65.01  E-value: 1.73e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 205 EGDTFEYPHHVKYSCNPGFLLVGSTSrqcsSNGEWTNEPANCKATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCD---- 278
Cdd:PHA02831   36 ENKVYEENENLEYKCNNNFDKVFVTC----NNGSWSTKNMCIGKRNCKDPVTILNGYIKNKKDQYSfgDSVTYACKvnkl 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 279 HGYRLVGQVQRICLaEGIWGGNEPRCEEIRCSvLPTLPNGYIEGSETSF--GAVAVFRCLETMTHEGASKAKCMEDGQWS 356
Cdd:PHA02831  112 EKYSIVGNETVKCI-NKQWVPKYPVCKLIRCK-YPALQNGFLNVFEKKFyyGDIVNFKCKKGFILLGSSVSTCDINSIWY 189

                  ....*..
gi 1143474957 357 APIPRCL 363
Cdd:PHA02831  190 PGIPKCV 196
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
193-246 6.74e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.92  E-value: 6.74e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957  193 CPDPGDIENGLREGDTFEYPH--HVKYSCNPGFLLVGSTSRQCSSNGEWTNEPANC 246
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYgdTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
251-304 6.03e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.23  E-value: 6.03e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957  251 CSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRC 304
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSygDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
206-483 1.96e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.90  E-value: 1.96e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 206 GDTFEYphhvkySCNPGFLL--VGSTSRQCSSNGeWT--NEpanCKATECSRPSSPLHGKVVGSSLTYQSVVTYSCDHGY 281
Cdd:PHA02927   47 GDTIEY------LCLPGYRKqkMGPIYAKCTGTG-WTlfNQ---CIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGY 116
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 282 RLVGQVQRIC----LAEGIWGGNEPRCEEIRCSVLPTLPNGYIEGSETSFgavavfrcletmthegaskakcmedgqwsa 357
Cdd:PHA02927  117 QLIGESKSYCelgsTGSMVWNPEAPICESVKCQSPPSISNGRHNGYEDFY------------------------------ 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 358 piprclascrvphiqngkirdksegqliASGSKVIVECNKQHEANIDERLICSNSTWSHVPVCSPLSChnwpprvPHARI 437
Cdd:PHA02927  167 ----------------------------TDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKC-------PHPTI 211
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1143474957 438 LFSKSSHGSIAKYECNngyhpnrNNQIIKCLYGEWTKDGPPMKCLP 483
Cdd:PHA02927  212 SNGYLSSGFKRSYSYN-------DNVDFKCKYGYKLSGSSSSTCSP 250
PHA02927 PHA02927
secreted complement-binding protein; Provisional
377-557 2.91e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.13  E-value: 2.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 377 RDKSEGQL----IASGSKVIVECNKQHEANIDERLICS-NSTWSHV-----PVCSPLSCHNwPPRVPHARILFSKS--SH 444
Cdd:PHA02927   90 RDIDNGQLdiggVDFGSSITYSCNSGYQLIGESKSYCElGSTGSMVwnpeaPICESVKCQS-PPSISNGRHNGYEDfyTD 168
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 445 GSIAKYECNNGYHPNRNNQIIkCLYGEWTKdgpPMKCLPSWCEHPSKTYGTLPGGqillegilgayefqsYIQKVEEGRA 524
Cdd:PHA02927  169 GSVVTYSCNSGYSLIGNSGVL-CSGGEWSD---PPTCQIVKCPHPTISNGYLSSG---------------FKRSYSYNDN 229
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1143474957 525 ISFQCGKGNYLIGPPKATCVNGE-WMPKVsPKCV 557
Cdd:PHA02927  230 VDFKCKYGYKLSGSSSSTCSPGNtWQPEL-PKCV 262
Sushi pfam00084
Sushi repeat (SCR repeat);
309-362 3.15e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 53.27  E-value: 3.15e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957 309 CSVLPTLPNGYIEGS--ETSFGAVAVFRCLETMTHEGASKAKCMEDGQWSAPIPRC 362
Cdd:pfam00084   1 CPPPPDIPNGKVSATknEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
64-246 6.75e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 57.75  E-value: 6.75e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957  64 CHPLPNIENGFIRTAGD-LRFGSNAEYGCNKGYILVGASQRRC---QANKEWSSSQPVCRLQlKCGPPPEIPfavhDGSS 139
Cdd:PHA02639   22 CDKPDDISNGFITELMEkYEIGKLIEYTCNTDYALIGDRFRTCikdKNNAIWSNKAPFCMLK-ECNDPPSII----NGKI 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 140 FSGE--YDLDAEVAYNCipGYHK---FNAKGLSISKCLLNRknvaQWFGPDLRCKARACPDPG---DIENGLREGDTFEY 211
Cdd:PHA02639   97 YNKRemYKVGDEIYYVC--NEHKgvqYSLVGNEKITCIQDK----SWKPDPPICKMINCRFPAlqnGYINGIPSNKKFYY 170
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 1143474957 212 PHHVKYSCNPGFLLVGSTSRQCSSNGEWTNEPANC 246
Cdd:PHA02639  171 KTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTC 205
Sushi pfam00084
Sushi repeat (SCR repeat);
251-304 7.53e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.12  E-value: 7.53e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957 251 CSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRC 304
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNygASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
143-304 9.70e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 56.98  E-value: 9.70e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 143 EYDLDAEVAYNCIPGYHKFnakGLSISKCLLNRKNvAQWFGPDLRCKARACPDPGDIENG--LREGDTFEYPHHVKYSCN 220
Cdd:PHA02639   39 KYEIGKLIEYTCNTDYALI---GDRFRTCIKDKNN-AIWSNKAPFCMLKECNDPPSIINGkiYNKREMYKVGDEIYYVCN 114
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 221 P----GFLLVGSTSRQCSSNGEWTNEPANCKATECSRPS---SPLHGKVVGSSLTYQSVVTYSCDHGYRLVGQVQRICLA 293
Cdd:PHA02639  115 EhkgvQYSLVGNEKITCIQDKSWKPDPPICKMINCRFPAlqnGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNI 194
                         170
                  ....*....|.
gi 1143474957 294 EGIWGGNEPRC 304
Cdd:PHA02639  195 NATWFPSIPTC 205
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
309-362 1.21e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 51.31  E-value: 1.21e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957 309 CSVLPTLPNGYIEGSETSF--GAVAVFRCLETMTHEGASKAKCMEDGQWSAPIPRC 362
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYsyGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
247-420 1.61e-08

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 56.60  E-value: 1.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 247 KATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHGYRLVGQVQRICLAE---GIWGGNEPRCEEIRCSVLPTLPNGYIE 321
Cdd:PHA02639   18 KSIYCDKPDDISNGFITELMEKYEigKLIEYTCNTDYALIGDRFRTCIKDknnAIWSNKAPFCMLKECNDPPSIINGKIY 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 322 GSETSF--GAVAVFRCLE----TMTHEGASKAKCMEDGQWSAPIPRC-LASCRVPHIQNGKIRDKSEGQLIASGSKVIVE 394
Cdd:PHA02639   98 NKREMYkvGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKPDPPICkMINCRFPALQNGYINGIPSNKKFYYKTRVGFS 177
                         170       180
                  ....*....|....*....|....*...
gi 1143474957 395 CNKQHEANIDERLICS-NSTW-SHVPVC 420
Cdd:PHA02639  178 CKSGFDLVGEKYSTCNiNATWfPSIPTC 205
Sushi pfam00084
Sushi repeat (SCR repeat);
193-246 1.68e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.96  E-value: 1.68e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957 193 CPDPGDIENGLREGDTFEYPHH--VKYSCNPGFLLVGSTSRQCSSNGEWTNEPANC 246
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGasVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
309-362 2.03e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.99  E-value: 2.03e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957  309 CSVLPTLPNGYIEGSETSF--GAVAVFRCLETMTHEGASKAKCMEDGQWSAPIPRC 362
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYsyGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
234-365 1.63e-07

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 53.55  E-value: 1.63e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 234 SSNGEWtNEPANCKATECsRPSSPLHGKV--VGSSLTYQSVVTYSCDHGYRLVGQVQRICLAEGiWgGNEPRCEEiRCSv 311
Cdd:PHA02954  114 NGNTSW-NDTVTCPNAEC-QPLQLEHGSCqpVKEKYSFGEHITINCDVGYEVIGASYISCTANS-W-NVIPSCQQ-KCD- 187
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1143474957 312 LPTLPNGYIEGSETSFGAVAVFRCLETMTHEGASKAKCMeDGQWSAPIPRCLAS 365
Cdd:PHA02954  188 IPSLSNGLISGSTFSIGGVIHLSCKSGFTLTGSPSSTCI-DGKWNPVLPICVRS 240
Sushi pfam00084
Sushi repeat (SCR repeat);
64-118 1.70e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.70e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1143474957  64 CHPLPNIENGFIR-TAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVC 118
Cdd:pfam00084   1 CPPPPDIPNGKVSaTKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02831 PHA02831
EEV host range protein; Provisional
177-304 4.06e-07

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 51.92  E-value: 4.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 177 NVAQWFGPDLRCKARACPDPGDIENGL--REGDTFEYPHHVKYSCNPGFL----LVGSTSRQCSsNGEWTNEPANCKATE 250
Cdd:PHA02831   62 NNGSWSTKNMCIGKRNCKDPVTILNGYikNKKDQYSFGDSVTYACKVNKLekysIVGNETVKCI-NKQWVPKYPVCKLIR 140
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1143474957 251 CSRPSspLHGKVVGS---SLTYQSVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRC 304
Cdd:PHA02831  141 CKYPA--LQNGFLNVfekKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
PHA02817 PHA02817
EEV Host range protein; Provisional
246-362 5.06e-07

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 51.09  E-value: 5.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 246 CKATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHG-----YRLVGQVQRICLAEGIWGGNEPRCEEIRCSvLPTLPNG 318
Cdd:PHA02817   19 CDLNKCCYPPSIKNGYIYNKKTEYNigSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCR-FPALQNG 97
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1143474957 319 YIEGSETS----FGAVAVFRCLETMTHEGASKAKCMEDGQWSAPIPRC 362
Cdd:PHA02817   98 FVNGIPDSkkfyYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
PHA02831 PHA02831
EEV host range protein; Provisional
407-571 1.02e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 50.76  E-value: 1.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 407 LICSNSTWSHVPVC-SPLSCHNwPPRVPHARILFSKS--SHGSIAKYECNNG---YHPNRNNQIIKCLYGEWTKDGPPMK 480
Cdd:PHA02831   59 VTCNNGSWSTKNMCiGKRNCKD-PVTILNGYIKNKKDqySFGDSVTYACKVNkleKYSIVGNETVKCINKQWVPKYPVCK 137
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 481 CLPswCEHPSktygtlpggqiLLEGILGAYEFQSYIqkveeGRAISFQCGKGNYLIGPPKATC-VNGEWMPKVsPKCVS- 558
Cdd:PHA02831  138 LIR--CKYPA-----------LQNGFLNVFEKKFYY-----GDIVNFKCKKGFILLGSSVSTCdINSIWYPGI-PKCVKd 198
                         170
                  ....*....|...
gi 1143474957 559 QTHPMIEGKILWD 571
Cdd:PHA02831  199 KVHNEIQPNYLFD 211
PHA02817 PHA02817
EEV Host range protein; Provisional
304-421 1.73e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 49.55  E-value: 1.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 304 CEEIRCSVLPTLPNGYI--EGSETSFGAVAVFRCLETM-----THEGASKAKCMEDGQWSAPIPRC-LASCRVPHIQNGK 375
Cdd:PHA02817   19 CDLNKCCYPPSIKNGYIynKKTEYNIGSNVTFFCGNNTrgvryTLVGEKNIICEKDGKWNKEFPVCkIIRCRFPALQNGF 98
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1143474957 376 IRDKSEGQLIASGSKVIVECNKQHEANIDERLICS-NSTW-SHVPVCS 421
Cdd:PHA02817   99 VNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGiNSSWiPKVPICS 146
PHA02817 PHA02817
EEV Host range protein; Provisional
188-304 4.65e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 48.01  E-value: 4.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 188 CKARACPDPGDIENGLREGDTFEYP--HHVKYSCNPG-----FLLVGSTSRQCSSNGEWTNEPANCKATECSRPSSPlHG 260
Cdd:PHA02817   19 CDLNKCCYPPSIKNGYIYNKKTEYNigSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPALQ-NG 97
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 1143474957 261 KVVG----SSLTYQSVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRC 304
Cdd:PHA02817   98 FVNGipdsKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
PHA02817 PHA02817
EEV Host range protein; Provisional
118-239 1.25e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 43.78  E-value: 1.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 118 CRLQLKCGPPPEIPFAVHDGSSfsgEYDLDAEVAYNCipgyhKFNAKGLSISkcLLNRKNV-----AQWFGPDLRCKARA 192
Cdd:PHA02817   19 CDLNKCCYPPSIKNGYIYNKKT---EYNIGSNVTFFC-----GNNTRGVRYT--LVGEKNIicekdGKWNKEFPVCKIIR 88
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1143474957 193 CPDPG---DIENGLREGDTFEYPHHVKYSCNPGFLLVGSTSRQCSSNGEW 239
Cdd:PHA02817   89 CRFPAlqnGFVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSW 138
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
425-481 1.77e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 39.75  E-value: 1.77e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 425 CHNwPPRVPHARILFSKS--SHGSIAKYECNNGYHPnRNNQIIKCL-YGEWTkdGPPMKC 481
Cdd:cd00033     1 CPP-PPVPENGTVTGSKGsySYGSTVTYSCNEGYTL-VGSSTITCTeNGGWS--PPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
309-557 6.71e-04

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 42.38  E-value: 6.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 309 CSVlPTLPNGYIEGSETSFG--AVAVFRClETMTHEGASKAKCMEDgQWSAPIP---RCLASCRVPHIQNGKIRD-KSEG 382
Cdd:PHA02954   21 CTV-PTMNNAKLTSTETSFNdkQKVTFTC-DSGYYSLDPNAVCETD-KWKYENPckkMCTVSDYVSELYDKPLYEvNSTI 97
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 383 QLIASGSKVIVECNKQHeaniderlicSNSTWSHVPVCSPLSCHNWPPRVPHARILFSKSSHGSIAKYECNNGYHPnRNN 462
Cdd:PHA02954   98 TLICKDETKYFRCEEKN----------GNTSWNDTVTCPNAECQPLQLEHGSCQPVKEKYSFGEHITINCDVGYEV-IGA 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 463 QIIKCLYGEWTkdgppmkCLPSW---CEHPSKTYGTLPGGQILLEGIlgayefqsyiqkveegraISFQCGKGNYLIGPP 539
Cdd:PHA02954  167 SYISCTANSWN-------VIPSCqqkCDIPSLSNGLISGSTFSIGGV------------------IHLSCKSGFTLTGSP 221
                         250
                  ....*....|....*...
gi 1143474957 540 KATCVNGEWMPkVSPKCV 557
Cdd:PHA02954  222 SSTCIDGKWNP-VLPICV 238
PHA02831 PHA02831
EEV host range protein; Provisional
48-174 1.47e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 40.75  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957  48 MCDGEcgLSCVNPIAmchplpnIENGFIRTAGD-LRFGSNAEYGC--NK--GYILVGASQRRCqANKEWSSSQPVCRLqL 122
Cdd:PHA02831   71 MCIGK--RNCKDPVT-------ILNGYIKNKKDqYSFGDSVTYACkvNKleKYSIVGNETVKC-INKQWVPKYPVCKL-I 139
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1143474957 123 KCGPPpeipfAVHDG--SSFSGEYDLDAEVAYNCIPGyhkFNAKGLSISKCLLN 174
Cdd:PHA02831  140 RCKYP-----ALQNGflNVFEKKFYYGDIVNFKCKKG---FILLGSSVSTCDIN 185
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
425-481 2.32e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.74  E-value: 2.32e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957  425 CHNwPPRVPHARILFSKS--SHGSIAKYECNNGYHPNRNNqIIKCL-YGEWTkdGPPMKC 481
Cdd:smart00032   1 CPP-PPDIENGTVTSSSGtySYGDTVTYSCDPGYTLIGSS-TITCLeNGTWS--PPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
207-304 3.18e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 40.07  E-value: 3.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1143474957 207 DTFEYPHHVKYSCNPGFLLVGSTSRQCSSNgEWTNEPAnCKaTECSRPSSPlHGKVVGSSLTYQSVVTYSCDHGYRLVGQ 286
Cdd:PHA02954  145 EKYSFGEHITINCDVGYEVIGASYISCTAN-SWNVIPS-CQ-QKCDIPSLS-NGLISGSTFSIGGVIHLSCKSGFTLTGS 220
                          90
                  ....*....|....*...
gi 1143474957 287 VQRICLaEGIWGGNEPRC 304
Cdd:PHA02954  221 PSSTCI-DGKWNPVLPIC 237
Sushi pfam00084
Sushi repeat (SCR repeat);
520-556 8.02e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 35.17  E-value: 8.02e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1143474957 520 EEGRAISFQCGKGNYLIGPPKATCV-NGEWMPKVsPKC 556
Cdd:pfam00084  20 NYGASVSYECDPGYRLVGSPTITCQeDGTWSPPF-PEC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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