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Conserved domains on  [gi|1063731659|ref|NP_001331241|]
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phospholipid:diacylglycerol acyltransferase [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN02517 super family cl28681
phosphatidylcholine-sterol O-acyltransferase
6-527 0e+00

phosphatidylcholine-sterol O-acyltransferase


The actual alignment was detected with superfamily member PLN02517:

Pssm-ID: 178132  Cd Length: 642  Bit Score: 1073.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659   6 PLCWVEHMSLDNETGLDPAGIRVRAVSGLVAADYFAPGYFVWAVLIANLAHIGYEEKNMYMAAYDWRLSFQNTEVRDQTL 85
Cdd:PLN02517  117 PLCWVEHMSLDNETGLDPPGIRVRAVSGLVAADYFAPGYFVWAVLIANLARIGYEEKNMYMAAYDWRLSFQNTEVRDQTL 196
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659  86 SRMKSNIELMVSTNGGKKAVIVPHSMGVLYFLHFMKWVEAPAPLGGGGGPDWCAKYIKAVMNIGGPFLGVPKAVAGLFSA 165
Cdd:PLN02517  197 SRLKSNIELMVATNGGKKVVVVPHSMGVLYFLHFMKWVEAPAPMGGGGGPGWCAKHIKAVMNIGGPFLGVPKAVSGLFSA 276
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 166 EAKDVAVARAIAPGFLDTDIFRLQTLQHVMRMTRTWDSTMSMLPKGGDTIWGGLDWSPEKGHTCCGKKQKNNETCGEA-- 243
Cdd:PLN02517  277 EAKDIAVARAIAPGVLDSDLFGLQTLQHVMRMTRTWDSTMSMLPKGGETIWGDLDWSPEEGYNCDGKKQKNNDTQLANqd 356
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 244 -GENGVSKKSPVNYGRMISFGKEVAEAAPSEINNIDFRGAVKGQSIP-NHTCRDVWTEYHDMGIAGIKAIAEYKVYTAGE 321
Cdd:PLN02517  357 nGNSDVKQKEPVNYGRIISFGKDVAEAPSSQIERIDFKDAVKGNSVAsNTSCGDVWTEYHEMGREGIKAVAEYKVYTAGS 436
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 322 AIDLLHYVAPKMMARGAAHFSYGIADDLDDTKYQDPKYWSNPLETKLPNAPEMEIYSLYGVGIPTERAYVYKLNQSPDSC 401
Cdd:PLN02517  437 VLDLLRFVAPKMMQRGDAHFSYGIADNLDDPKYQHYKYWSNPLETKLPNAPEMEIYSLYGVGIPTERSYVYKLSPSDECS 516
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 402 IPFQIFTSAHEEDEDSCLKAGVYNVDGDETVPVLSAGYMCAKAWRGKTRFNPSGIKTYIREYNHSPPANLLEGRGTQSGA 481
Cdd:PLN02517  517 IPFQIDTSADGGDEDSCLKGGVYFVDGDETVPVLSAGFMCAKGWRGKTRFNPSGIRTYIREYQHSPPANLLEGRGTQSGA 596
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 1063731659 482 HVDIMGNFALIEDIMRVAAGGNGSDIGHDQVHSGIFEWSERIDLKL 527
Cdd:PLN02517  597 HVDIMGNFALIEDVLRVAAGATGEELGGDRVYSDIFKWSEKINLKL 642
 
Name Accession Description Interval E-value
PLN02517 PLN02517
phosphatidylcholine-sterol O-acyltransferase
6-527 0e+00

phosphatidylcholine-sterol O-acyltransferase


Pssm-ID: 178132  Cd Length: 642  Bit Score: 1073.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659   6 PLCWVEHMSLDNETGLDPAGIRVRAVSGLVAADYFAPGYFVWAVLIANLAHIGYEEKNMYMAAYDWRLSFQNTEVRDQTL 85
Cdd:PLN02517  117 PLCWVEHMSLDNETGLDPPGIRVRAVSGLVAADYFAPGYFVWAVLIANLARIGYEEKNMYMAAYDWRLSFQNTEVRDQTL 196
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659  86 SRMKSNIELMVSTNGGKKAVIVPHSMGVLYFLHFMKWVEAPAPLGGGGGPDWCAKYIKAVMNIGGPFLGVPKAVAGLFSA 165
Cdd:PLN02517  197 SRLKSNIELMVATNGGKKVVVVPHSMGVLYFLHFMKWVEAPAPMGGGGGPGWCAKHIKAVMNIGGPFLGVPKAVSGLFSA 276
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 166 EAKDVAVARAIAPGFLDTDIFRLQTLQHVMRMTRTWDSTMSMLPKGGDTIWGGLDWSPEKGHTCCGKKQKNNETCGEA-- 243
Cdd:PLN02517  277 EAKDIAVARAIAPGVLDSDLFGLQTLQHVMRMTRTWDSTMSMLPKGGETIWGDLDWSPEEGYNCDGKKQKNNDTQLANqd 356
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 244 -GENGVSKKSPVNYGRMISFGKEVAEAAPSEINNIDFRGAVKGQSIP-NHTCRDVWTEYHDMGIAGIKAIAEYKVYTAGE 321
Cdd:PLN02517  357 nGNSDVKQKEPVNYGRIISFGKDVAEAPSSQIERIDFKDAVKGNSVAsNTSCGDVWTEYHEMGREGIKAVAEYKVYTAGS 436
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 322 AIDLLHYVAPKMMARGAAHFSYGIADDLDDTKYQDPKYWSNPLETKLPNAPEMEIYSLYGVGIPTERAYVYKLNQSPDSC 401
Cdd:PLN02517  437 VLDLLRFVAPKMMQRGDAHFSYGIADNLDDPKYQHYKYWSNPLETKLPNAPEMEIYSLYGVGIPTERSYVYKLSPSDECS 516
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 402 IPFQIFTSAHEEDEDSCLKAGVYNVDGDETVPVLSAGYMCAKAWRGKTRFNPSGIKTYIREYNHSPPANLLEGRGTQSGA 481
Cdd:PLN02517  517 IPFQIDTSADGGDEDSCLKGGVYFVDGDETVPVLSAGFMCAKGWRGKTRFNPSGIRTYIREYQHSPPANLLEGRGTQSGA 596
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 1063731659 482 HVDIMGNFALIEDIMRVAAGGNGSDIGHDQVHSGIFEWSERIDLKL 527
Cdd:PLN02517  597 HVDIMGNFALIEDVLRVAAGATGEELGGDRVYSDIFKWSEKINLKL 642
LCAT pfam02450
Lecithin:cholesterol acyltransferase; Lecithin:cholesterol acyltransferase (LCAT) is involved ...
8-487 4.53e-58

Lecithin:cholesterol acyltransferase; Lecithin:cholesterol acyltransferase (LCAT) is involved in extracellular metabolism of plasma lipoproteins, including cholesterol.


Pssm-ID: 396835  Cd Length: 383  Bit Score: 197.77  E-value: 4.53e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659   8 CWVE--HMSLDNETGL--DPAGIRVRAVSGLVAADYFAP----GYFVWAVLIANLAHIGYE-EKNMYMAAYDWRLSFQNt 78
Cdd:pfam02450  16 CWIDntHVVLNPSTGLqpDPPGVKIRAAQGFESVEYLDYsklaGYWIWHKVVQNLVNIGYErNKTVRAAPYDWRLSLEE- 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659  79 evRDQTLSRMKSNIELMVStNGGKKAVIVPHSMGVLYFLHFMKWVEAPAplgggggpdWCAKYIKAVMNIGGPFLGVPKA 158
Cdd:pfam02450  95 --RDKYFHKLKQLIEEAHK-LYGKKVVLIGHSMGNLLVLYFLLWVVAEA---------WKDQHIDAFISLGAPLLGSPKA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 159 VAGLFSAEAKDVAVARAIApgfldtdifrlqtlqhVMRMTRTWDSTMSMLPKGGDTIWGGLDWSPEkghtccgkkQKNNE 238
Cdd:pfam02450 163 VRALASGYNFGIPILSEIT----------------LRGLQRSFSSSPWMLPKGKYVLWSDVAWPSD---------EIFIQ 217
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 239 TcgeagengvsKKSPVNYGRMISFgkevaeaapseinnidFRGAVKGQSIPNHTcrdvwteyhdmgiagikaiaeykvyt 318
Cdd:pfam02450 218 T----------PSINYTYGALVRF----------------FDDETINVDALGFT-------------------------- 245
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 319 ageaidlLHYVAPKMMARGAAHFSYGIADDLDDTKYQDPKYWSNPLETKLPNAPEMEIYSLYGVGIPTERAYVYKLNQSP 398
Cdd:pfam02450 246 -------LNTLDGWYMWKVSRDLDGGLPYLEAELAKNDIKYWVNPEETPLPVAPGVKVYCIYGVGLPTERGYYYTPGKTS 318
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 399 dscipfqiftSAHEEDEDSCLKAGVYNVDGDETVPVLSAGyMCAKaWRGktrfNPSGIKTYIREYNHsppanllegrGTQ 478
Cdd:pfam02450 319 ----------SPILSRIDYEDPVGIVSGDGDGTVPKRSLE-LCKN-WQG----LPAGQNVTVHELKH----------GSR 372

                  ....*....
gi 1063731659 479 SGAHVDIMG 487
Cdd:pfam02450 373 SAEHVDILG 381
 
Name Accession Description Interval E-value
PLN02517 PLN02517
phosphatidylcholine-sterol O-acyltransferase
6-527 0e+00

phosphatidylcholine-sterol O-acyltransferase


Pssm-ID: 178132  Cd Length: 642  Bit Score: 1073.62  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659   6 PLCWVEHMSLDNETGLDPAGIRVRAVSGLVAADYFAPGYFVWAVLIANLAHIGYEEKNMYMAAYDWRLSFQNTEVRDQTL 85
Cdd:PLN02517  117 PLCWVEHMSLDNETGLDPPGIRVRAVSGLVAADYFAPGYFVWAVLIANLARIGYEEKNMYMAAYDWRLSFQNTEVRDQTL 196
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659  86 SRMKSNIELMVSTNGGKKAVIVPHSMGVLYFLHFMKWVEAPAPLGGGGGPDWCAKYIKAVMNIGGPFLGVPKAVAGLFSA 165
Cdd:PLN02517  197 SRLKSNIELMVATNGGKKVVVVPHSMGVLYFLHFMKWVEAPAPMGGGGGPGWCAKHIKAVMNIGGPFLGVPKAVSGLFSA 276
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 166 EAKDVAVARAIAPGFLDTDIFRLQTLQHVMRMTRTWDSTMSMLPKGGDTIWGGLDWSPEKGHTCCGKKQKNNETCGEA-- 243
Cdd:PLN02517  277 EAKDIAVARAIAPGVLDSDLFGLQTLQHVMRMTRTWDSTMSMLPKGGETIWGDLDWSPEEGYNCDGKKQKNNDTQLANqd 356
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 244 -GENGVSKKSPVNYGRMISFGKEVAEAAPSEINNIDFRGAVKGQSIP-NHTCRDVWTEYHDMGIAGIKAIAEYKVYTAGE 321
Cdd:PLN02517  357 nGNSDVKQKEPVNYGRIISFGKDVAEAPSSQIERIDFKDAVKGNSVAsNTSCGDVWTEYHEMGREGIKAVAEYKVYTAGS 436
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 322 AIDLLHYVAPKMMARGAAHFSYGIADDLDDTKYQDPKYWSNPLETKLPNAPEMEIYSLYGVGIPTERAYVYKLNQSPDSC 401
Cdd:PLN02517  437 VLDLLRFVAPKMMQRGDAHFSYGIADNLDDPKYQHYKYWSNPLETKLPNAPEMEIYSLYGVGIPTERSYVYKLSPSDECS 516
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 402 IPFQIFTSAHEEDEDSCLKAGVYNVDGDETVPVLSAGYMCAKAWRGKTRFNPSGIKTYIREYNHSPPANLLEGRGTQSGA 481
Cdd:PLN02517  517 IPFQIDTSADGGDEDSCLKGGVYFVDGDETVPVLSAGFMCAKGWRGKTRFNPSGIRTYIREYQHSPPANLLEGRGTQSGA 596
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 1063731659 482 HVDIMGNFALIEDIMRVAAGGNGSDIGHDQVHSGIFEWSERIDLKL 527
Cdd:PLN02517  597 HVDIMGNFALIEDVLRVAAGATGEELGGDRVYSDIFKWSEKINLKL 642
LCAT pfam02450
Lecithin:cholesterol acyltransferase; Lecithin:cholesterol acyltransferase (LCAT) is involved ...
8-487 4.53e-58

Lecithin:cholesterol acyltransferase; Lecithin:cholesterol acyltransferase (LCAT) is involved in extracellular metabolism of plasma lipoproteins, including cholesterol.


Pssm-ID: 396835  Cd Length: 383  Bit Score: 197.77  E-value: 4.53e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659   8 CWVE--HMSLDNETGL--DPAGIRVRAVSGLVAADYFAP----GYFVWAVLIANLAHIGYE-EKNMYMAAYDWRLSFQNt 78
Cdd:pfam02450  16 CWIDntHVVLNPSTGLqpDPPGVKIRAAQGFESVEYLDYsklaGYWIWHKVVQNLVNIGYErNKTVRAAPYDWRLSLEE- 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659  79 evRDQTLSRMKSNIELMVStNGGKKAVIVPHSMGVLYFLHFMKWVEAPAplgggggpdWCAKYIKAVMNIGGPFLGVPKA 158
Cdd:pfam02450  95 --RDKYFHKLKQLIEEAHK-LYGKKVVLIGHSMGNLLVLYFLLWVVAEA---------WKDQHIDAFISLGAPLLGSPKA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 159 VAGLFSAEAKDVAVARAIApgfldtdifrlqtlqhVMRMTRTWDSTMSMLPKGGDTIWGGLDWSPEkghtccgkkQKNNE 238
Cdd:pfam02450 163 VRALASGYNFGIPILSEIT----------------LRGLQRSFSSSPWMLPKGKYVLWSDVAWPSD---------EIFIQ 217
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 239 TcgeagengvsKKSPVNYGRMISFgkevaeaapseinnidFRGAVKGQSIPNHTcrdvwteyhdmgiagikaiaeykvyt 318
Cdd:pfam02450 218 T----------PSINYTYGALVRF----------------FDDETINVDALGFT-------------------------- 245
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 319 ageaidlLHYVAPKMMARGAAHFSYGIADDLDDTKYQDPKYWSNPLETKLPNAPEMEIYSLYGVGIPTERAYVYKLNQSP 398
Cdd:pfam02450 246 -------LNTLDGWYMWKVSRDLDGGLPYLEAELAKNDIKYWVNPEETPLPVAPGVKVYCIYGVGLPTERGYYYTPGKTS 318
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659 399 dscipfqiftSAHEEDEDSCLKAGVYNVDGDETVPVLSAGyMCAKaWRGktrfNPSGIKTYIREYNHsppanllegrGTQ 478
Cdd:pfam02450 319 ----------SPILSRIDYEDPVGIVSGDGDGTVPKRSLE-LCKN-WQG----LPAGQNVTVHELKH----------GSR 372

                  ....*....
gi 1063731659 479 SGAHVDIMG 487
Cdd:pfam02450 373 SAEHVDILG 381
PLN02733 PLN02733
phosphatidylcholine-sterol O-acyltransferase
33-156 4.58e-08

phosphatidylcholine-sterol O-acyltransferase


Pssm-ID: 215390  Cd Length: 440  Bit Score: 55.41  E-value: 4.58e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063731659  33 GLVAADYFAPGYFV-------WAVLIANLAHIGYEE-KNMYMAAYDWRLSfqNtevR-DQTLSRMKSNIELMVSTNGGKK 103
Cdd:PLN02733   89 GLYAIDILDPDVIIrldevyyFHDMIEQLIKWGYKEgKTLFGFGYDFRQS--N---RlPETMDGLKKKLETVYKASGGKK 163
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1063731659 104 AVIVPHSMGVLYFLHFMkwveapaplggGGGPDWCAKYIKAVMNIGGPFLGVP 156
Cdd:PLN02733  164 VNIISHSMGGLLVKCFM-----------SLHSDVFEKYVNSWIAIAAPFQGAP 205
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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