NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1063733635|ref|NP_001330409|]
View 

sigma factor E [Arabidopsis thaliana]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
RpoD super family cl33954
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
271-516 2.27e-51

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


The actual alignment was detected with superfamily member COG0568:

Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 176.01  E-value: 2.27e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 271 KKIEIG-RAARNKLIKHNLRLVLFVMNKYFHeftNGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRS 349
Cdd:COG0568    22 RRIQAGdEEAKRKLVEANLRLVVSIAKKYQG---RGLPLLDLIQEGNLGLMKAVEKFDPERGFRFSTYATWWIRQAITRA 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 350 -MTTSNFTRVPFGL-ESVRVeIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSkhSVTQEEfinG 427
Cdd:COG0568    99 iADQWRTIRLPVHMaETLNK-LRRAKRQLLQELGREPTPEEIAEELGVPEEKVREMLRLAREPVSLDA--PVGDDE---D 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 428 ITDVDGVGANNSRQPA------LLRLALDDVLDSLKPKESLVIRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEVKALM 501
Cdd:COG0568   173 SELGDLLEDEEAPSPEealeeeLLREELREALDTLTEREREILRLRFGLDDGEPHTLEEIGKEFGVSRERVRQIEAKALR 252
                         250
                  ....*....|....*
gi 1063733635 502 KLKHQARVDYLRQYI 516
Cdd:COG0568   253 KLRHPLRSRKLRDYL 267
Sigma70_r3 pfam04539
Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the ...
238-280 2.34e-03

Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the sigma-factor. Region is not normally involved in the recognition of promoter DNA, but as some specific bacterial promoters containing an extended -10 promoter element, residues within region 3 play an important role. Region 3 primarily is involved in binding the core RNA polymerase in the holoenzyme.


:

Pssm-ID: 427997 [Multi-domain]  Cd Length: 78  Bit Score: 36.81  E-value: 2.34e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1063733635 238 LLEVKDVLQKSLGREPREAEIAGEINMTAGEVKKKIEIGRAAR 280
Cdd:pfam04539   6 IKRAQRELEQELGREPTPEEIAEELGLSPEKVREVLEAAREPV 48
 
Name Accession Description Interval E-value
RpoD COG0568
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
271-516 2.27e-51

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 176.01  E-value: 2.27e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 271 KKIEIG-RAARNKLIKHNLRLVLFVMNKYFHeftNGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRS 349
Cdd:COG0568    22 RRIQAGdEEAKRKLVEANLRLVVSIAKKYQG---RGLPLLDLIQEGNLGLMKAVEKFDPERGFRFSTYATWWIRQAITRA 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 350 -MTTSNFTRVPFGL-ESVRVeIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSkhSVTQEEfinG 427
Cdd:COG0568    99 iADQWRTIRLPVHMaETLNK-LRRAKRQLLQELGREPTPEEIAEELGVPEEKVREMLRLAREPVSLDA--PVGDDE---D 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 428 ITDVDGVGANNSRQPA------LLRLALDDVLDSLKPKESLVIRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEVKALM 501
Cdd:COG0568   173 SELGDLLEDEEAPSPEealeeeLLREELREALDTLTEREREILRLRFGLDDGEPHTLEEIGKEFGVSRERVRQIEAKALR 252
                         250
                  ....*....|....*
gi 1063733635 502 KLKHQARVDYLRQYI 516
Cdd:COG0568   253 KLRHPLRSRKLRDYL 267
PRK07406 PRK07406
RNA polymerase sigma factor RpoD; Validated
238-516 2.43e-50

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 236012 [Multi-domain]  Cd Length: 373  Bit Score: 176.51  E-value: 2.43e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 238 LLEVKDVLQKSLGREPREAEIAGEINMTAGEVKKKIEIGRAARNKLIKHNLRLVLFVMNKYFHEftnGPKFQDLCQAGMR 317
Cdd:PRK07406   96 LEELREQFESELGREPSDKEWAELVDMPLPKFRRRLMLGRRAKEKMVQSNLRLVVSIAKKYMNR---GLSFQDLIQEGSL 172
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 318 GLITAIDRFEPKRKFRLSTYGLFWIRHAIIRSMTTSNFT-RVPFGLESVRVEIYKAKTELWFEMGRPPTEDEVVERLKIT 396
Cdd:PRK07406  173 GLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQSRTiRLPVHLYETISRIKKTTKVLSQEFGRKPTEEEIAESMEMT 252
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 397 PERYREVLRAAKPVLSLNSkhSVTQEE------FI--NGITDVDGVGANnsrqpaLLRLALDDVLDSLKPKESLVIRQRY 468
Cdd:PRK07406  253 IEKLRFIAKSAQLPISLET--PIGKEEdsrlgdFIeaDGETPEDDVAKN------LLREDLEGVLATLSPRERDVLRLRY 324
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1063733635 469 GLDGKGDRTLGEIAGNLNISREMVRKHEVKALMKLKHQARVDYLRQYI 516
Cdd:PRK07406  325 GLDDGRMKTLEEIGQIFNVTRERIRQIEAKALRKLRHPNRNSVLKEYI 372
Sigma70_r3 pfam04539
Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the ...
366-439 2.59e-14

Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the sigma-factor. Region is not normally involved in the recognition of promoter DNA, but as some specific bacterial promoters containing an extended -10 promoter element, residues within region 3 play an important role. Region 3 primarily is involved in binding the core RNA polymerase in the holoenzyme.


Pssm-ID: 427997 [Multi-domain]  Cd Length: 78  Bit Score: 68.01  E-value: 2.59e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063733635 366 RVEIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSKHSVTQEEFING-ITDVDGVGANNS 439
Cdd:pfam04539   3 LNKIKRAQRELEQELGREPTPEEIAEELGLSPEKVREVLEAAREPVSLDTPVGEEEDGELGDlLEDDDIESPEEA 77
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
278-506 5.51e-09

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 55.05  E-value: 5.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 278 AARNKLIKHNLRLVLFVMNKYFhefTNGPKFQDLCQAGMRGLITAIDRFEPKRKFRlsTYGLFWIRHAIIRSMTTSNFTR 357
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYL---GDDADAEDLVQEAFLKLLEALDRFDPEGSFK--AWLFRIARNLILDYLRRKRRLR 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 358 VpfglesvrveiykaktelwfemgrppTEDEVVERLKITPERYREVLRAAkpvlslnskhsvtqeefingitdvdgvgan 437
Cdd:TIGR02937  76 R--------------------------ELDLLEELLDSDPSPEEELEQEE------------------------------ 99
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063733635 438 nsrqpalLRLALDDVLDSLKPKESLVIRQRYGldgkGDRTLGEIAGNLNISREMVRKHEVKALMKLKHQ 506
Cdd:TIGR02937 100 -------EREALREALEKLPEREREVLVLRYL----EGLSYKEIAEILGISVGTVKRRLKRARKKLREL 157
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
446-504 2.17e-05

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 42.09  E-value: 2.17e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063733635 446 RLALDDVLDSLKPKESLVIRQRYGldgkGDRTLGEIAGNLNISREMVRKHEVKALMKLK 504
Cdd:cd06171     1 RERLEEALDKLPEREREVILLRFG----EGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
Sigma70_r3 pfam04539
Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the ...
238-280 2.34e-03

Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the sigma-factor. Region is not normally involved in the recognition of promoter DNA, but as some specific bacterial promoters containing an extended -10 promoter element, residues within region 3 play an important role. Region 3 primarily is involved in binding the core RNA polymerase in the holoenzyme.


Pssm-ID: 427997 [Multi-domain]  Cd Length: 78  Bit Score: 36.81  E-value: 2.34e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1063733635 238 LLEVKDVLQKSLGREPREAEIAGEINMTAGEVKKKIEIGRAAR 280
Cdd:pfam04539   6 IKRAQRELEQELGREPTPEEIAEELGLSPEKVREVLEAAREPV 48
 
Name Accession Description Interval E-value
RpoD COG0568
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
271-516 2.27e-51

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 176.01  E-value: 2.27e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 271 KKIEIG-RAARNKLIKHNLRLVLFVMNKYFHeftNGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRS 349
Cdd:COG0568    22 RRIQAGdEEAKRKLVEANLRLVVSIAKKYQG---RGLPLLDLIQEGNLGLMKAVEKFDPERGFRFSTYATWWIRQAITRA 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 350 -MTTSNFTRVPFGL-ESVRVeIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSkhSVTQEEfinG 427
Cdd:COG0568    99 iADQWRTIRLPVHMaETLNK-LRRAKRQLLQELGREPTPEEIAEELGVPEEKVREMLRLAREPVSLDA--PVGDDE---D 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 428 ITDVDGVGANNSRQPA------LLRLALDDVLDSLKPKESLVIRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEVKALM 501
Cdd:COG0568   173 SELGDLLEDEEAPSPEealeeeLLREELREALDTLTEREREILRLRFGLDDGEPHTLEEIGKEFGVSRERVRQIEAKALR 252
                         250
                  ....*....|....*
gi 1063733635 502 KLKHQARVDYLRQYI 516
Cdd:COG0568   253 KLRHPLRSRKLRDYL 267
PRK07406 PRK07406
RNA polymerase sigma factor RpoD; Validated
238-516 2.43e-50

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 236012 [Multi-domain]  Cd Length: 373  Bit Score: 176.51  E-value: 2.43e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 238 LLEVKDVLQKSLGREPREAEIAGEINMTAGEVKKKIEIGRAARNKLIKHNLRLVLFVMNKYFHEftnGPKFQDLCQAGMR 317
Cdd:PRK07406   96 LEELREQFESELGREPSDKEWAELVDMPLPKFRRRLMLGRRAKEKMVQSNLRLVVSIAKKYMNR---GLSFQDLIQEGSL 172
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 318 GLITAIDRFEPKRKFRLSTYGLFWIRHAIIRSMTTSNFT-RVPFGLESVRVEIYKAKTELWFEMGRPPTEDEVVERLKIT 396
Cdd:PRK07406  173 GLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQSRTiRLPVHLYETISRIKKTTKVLSQEFGRKPTEEEIAESMEMT 252
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 397 PERYREVLRAAKPVLSLNSkhSVTQEE------FI--NGITDVDGVGANnsrqpaLLRLALDDVLDSLKPKESLVIRQRY 468
Cdd:PRK07406  253 IEKLRFIAKSAQLPISLET--PIGKEEdsrlgdFIeaDGETPEDDVAKN------LLREDLEGVLATLSPRERDVLRLRY 324
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1063733635 469 GLDGKGDRTLGEIAGNLNISREMVRKHEVKALMKLKHQARVDYLRQYI 516
Cdd:PRK07406  325 GLDDGRMKTLEEIGQIFNVTRERIRQIEAKALRKLRHPNRNSVLKEYI 372
PRK05949 PRK05949
RNA polymerase sigma factor; Validated
218-517 4.15e-45

RNA polymerase sigma factor; Validated


Pssm-ID: 180321 [Multi-domain]  Cd Length: 327  Bit Score: 161.16  E-value: 4.15e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 218 PVLSSTEHAWLFKLMQPMKALLEVKDVLQKSLGREPREAEIAGEINMTAGEVKKKIEIGRAARNKLIKHNLRLVLFVMNK 297
Cdd:PRK05949   31 PLLTHEQEIVYGKQVQQMMSLLEAKEALAKKLGREPSLPEWAEAVNLSETELKQTLKQGKRAKQKMIEANLRLVVAIAKK 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 298 YFHEftnGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRSMTTSNFT-RVPFGLESVRVEIYKAKTEL 376
Cdd:PRK05949  111 YQKR---NMEFLDLIQEGTLGLERGVEKFDPTRGYKFSTYAYWWIRQAITRAIAQQARTiRLPIHITEKLNKIKKTQREL 187
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 377 WFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSKHSVTQEEFINGITDVDGVGANNSRQPALLRLALDDVLDSL 456
Cdd:PRK05949  188 SQKLGRSATPAEIAKELELEPSQIREYLSMARQPISLDVRVGDNQDTELSELLEDEGPSPDQYITQELLRQDLNNLLAEL 267
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063733635 457 KPKESLVIRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEVKALMKLKHqaRVDYLRQYIV 517
Cdd:PRK05949  268 TPQQREVLTLRFGLEDGKELSLAKVGERLNLSRERVRQLEHQALAHLRR--RRANVKEYLA 326
PRK07405 PRK07405
RNA polymerase sigma factor SigD; Validated
218-504 1.68e-40

RNA polymerase sigma factor SigD; Validated


Pssm-ID: 180963 [Multi-domain]  Cd Length: 317  Bit Score: 148.37  E-value: 1.68e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 218 PVLSSTEHAWLFKLMQPMKALLEVKDVLQKSLGREPREAEIAGEINMTAGEVKKKIEIGRAARNKLIKHNLRLVLFVMNK 297
Cdd:PRK07405   21 PLLTHEEEILYGKQVQRLVALQEIREELAEELGREPTDAEWAKAAKLSEEELRSAIAEGEAAKRKMVEANLRLVVSVAKK 100
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 298 YFHEFTNgpkFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRSMTTSNFT-RVPFGLESVRVEIYKAKTEL 376
Cdd:PRK07405  101 YLKRNVD---LLDLIQEGTIGMQRGVEKFDPTKGYRFSTYAYWWIRQAITRAIAEKSRTiRLPIHITEKLNKIKKAQRQL 177
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 377 WFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSKHSVTQEEFINGITDVDGVGANNSRQPALLRLALDDVLDSL 456
Cdd:PRK07405  178 SQQLGRAATIGELAEELELTPKQVREYLERARQPLSLDLRVGDNQDTELGELLEDTGASPEDFATQSSLQLDLERLMEDL 257
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1063733635 457 KPKESLVIRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEVKALMKLK 504
Cdd:PRK07405  258 TPQQKEVIALRFGLEDGQPLTLAKIGERLNISRERVRQIEREALSKLR 305
PRK07598 PRK07598
RNA polymerase sigma factor SigC; Validated
234-516 1.21e-39

RNA polymerase sigma factor SigC; Validated


Pssm-ID: 236067 [Multi-domain]  Cd Length: 415  Bit Score: 148.48  E-value: 1.21e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 234 PMKALLEVKDVLQKSLGREP-------------------------REAEIAgeiNMTAGEVKKKIEIGRAARNKLIKHNL 288
Cdd:PRK07598  109 PYLRLIEVRERLTSELGHRPslerwaktadisladlkptlaegkrRWAEIA---KLTVEELEQIQKQGLRAKEHMIKANL 185
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 289 RLVLFVMNKYFHEftnGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRSMTTSNFT-RVPFGLESVRV 367
Cdd:PRK07598  186 RLVVSVAKKYQNR---GLELLDLVQEGTLGLERAVEKFDPTKGYRFSTYAYWWIRQGITRAIATQSRTiRLPVHITEKLN 262
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 368 EIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSKHSVTQEEFINGITDVDGVGANNSRQPALLRL 447
Cdd:PRK07598  263 KIKKAQRKISQEKGRTPTIEDIAQELEMTPTQVREVLLRVPRSVSLETKVGKDKDTELGDLLETDDISPEEMLMRESLQR 342
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063733635 448 ALDDVLDSLKPKESLVIRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEVKALMKLKHQARVDYLRQYI 516
Cdd:PRK07598  343 DLQHLLADLTSRERDVIRMRFGLADGHTYSLAEIGRALDLSRERVRQIESKALQKLRQPKRRNRIRDYL 411
PRK07921 PRK07921
RNA polymerase sigma factor SigB; Reviewed
276-515 3.02e-38

RNA polymerase sigma factor SigB; Reviewed


Pssm-ID: 181169 [Multi-domain]  Cd Length: 324  Bit Score: 142.56  E-value: 3.02e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 276 GRAARNKLIKHNLRLVLFVMNKYFhefTNGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRSMTTSNF 355
Cdd:PRK07921   84 GEAARRHLLEANLRLVVSLAKRYT---GRGMPLLDLIQEGNLGLIRAMEKFDYTKGFKFSTYATWWIRQAITRGMADQSR 160
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 356 T-RVPFGL-ESVRvEIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSKHSvTQEEFING--ITDV 431
Cdd:PRK07921  161 TiRLPVHLvEQVN-KLARIKRELHQQLGREATDEELAEESGIPEEKIADLLEHSRDPVSLDMPVG-SDEEAPLGdfIEDS 238
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 432 DGVGANNSRQPALLRLALDDVLDSLKPKESLVIRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEVKALMKLKHQARVDY 511
Cdd:PRK07921  239 EATSAENAVIAGLLHTDIRSVLATLDEREQQVIRLRFGLDDGQPRTLDQIGKLFGLSRERVRQIEREVMSKLRNGERADR 318

                  ....
gi 1063733635 512 LRQY 515
Cdd:PRK07921  319 LRSY 322
PRK09210 PRK09210
RNA polymerase sigma factor RpoD; Validated
268-516 3.44e-34

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 236413 [Multi-domain]  Cd Length: 367  Bit Score: 132.42  E-value: 3.44e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 268 EVKKKIEIG-RAARNKLIKHNLRLVLFVMNKYFhefTNGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAI 346
Cdd:PRK09210  118 ELAKRIEEGdEEAKQRLAEANLRLVVSIAKRYV---GRGMLFLDLIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAI 194
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 347 IRSMTTSNFT-RVPFGLESVRVEIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSkhSVTQEE-- 423
Cdd:PRK09210  195 TRAIADQARTiRIPVHMVETINKLIRVQRQLLQELGREPTPEEIAEEMDMPPEKVREILKIAQEPVSLET--PIGEEDds 272
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 424 ----FINgitdvDGVGANNSRQPA--LLRLALDDVLDSLKPKESLVIRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEV 497
Cdd:PRK09210  273 hlgdFIE-----DQDATSPADHAAyeLLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVGKVFGVTRERIRQIEA 347
                         250
                  ....*....|....*....
gi 1063733635 498 KALMKLKHQARVDYLRQYI 516
Cdd:PRK09210  348 KALRKLRHPSRSKQLKDFL 366
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
49-516 4.08e-34

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 134.74  E-value: 4.08e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635  49 PPREQVLIPAEKHNEKKRevTRRKPCKTPKKPLSLEHNSAPSCSLGVDYNEAAARLESIYKLSPATTTLVEDDVEDGGSK 128
Cdd:PRK05901   11 AAEEEAKKKLKKLAAKSK--SKGFITKEEIKEALESKKKTPEQIDQVLIFLSGMVKDTDDATESDIPKKKTKTAAKAAAA 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 129 AKVSRRRKRKESGEEKKVVVRNNVKKEKRMSLDKRIALKRNVQEKPVVA----SVDKKVTKRQQEEEKIERLVRDYSASN 204
Cdd:PRK05901   89 KAPAKKKLKDELDSSKKAEKKNALDKDDDLNYVKDIDVLNQADDDDDDDddddLDDDDIDDDDDDEDDDEDDDDDDVDDE 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 205 DIVSLDWKKMKIPPVLSSTEHAWLFKLMQPMKALLE--------VKDVLqKSLGREP-----REAEIAGEIN-------- 263
Cdd:PRK05901  169 DEEKKEAKELEKLSDDDDFVWDEDDSEALRQARKDAkltatadpVKAYL-KQIGKVKllnaeEEVELAKRIEaglyaeel 247
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 264 MTAGE---------VKKKIEIGRAARNKLIKHNLRLVLFVMNKYfhefTN-GPKFQDLCQAGMRGLITAIDRFEPKRKFR 333
Cdd:PRK05901  248 LAEGEkldpelrrdLQWIGRDGKRAKNHLLEANLRLVVSLAKRY----TNrGLSFLDLIQEGNLGLIKAVEKFDYTKGYK 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 334 LSTYGLFWIRHAIIRSMTTSNFT-RVPfglesVR-VE----IYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAA 407
Cdd:PRK05901  324 FSTYATWWIRQAITRAMADQARTiRIP-----VHmVEtinkLGRIERELLQELGREPTPEELAKEMGFTPEKVREIQKYN 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 408 KPVLSLNSkhSVTQEE------FI---NGITDVDGVGANnsrqpaLLRLALDDVLDSLKPKESLVIRQRYGL-DGKgDRT 477
Cdd:PRK05901  399 REPISLDK--TIGKEGdsqfgdFIedsEAVSPVDAVSFT------LLQDQLQEVLETLSEREAGVIRMRFGLtDGQ-PKT 469
                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 1063733635 478 LGEIAGNLNISREMVRKHEVKALMKLKHQARVDYLRQYI 516
Cdd:PRK05901  470 LDEIGQVYGVTRERIRQIESKTLRKLRHPSRSQVLRDFL 508
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
277-504 5.03e-30

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 117.23  E-value: 5.03e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 277 RAARNKLIKHNLRLVLFVMNKYFHEFtnGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAII---RSMtts 353
Cdd:COG1191    14 EEAREELIEEYLPLVKKIASRLAGRL--PAELDDLIQVGLIGLIEAIDRFDPSKGVSFETYAVPRIRGAILdylRDE--- 88
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 354 nfTRVPFGLESVRVEIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAK--PVLSLnskhsvtQEEFINGITDV 431
Cdd:COG1191    89 --DWVPRSVRELARKIEEAIEELEQELGREPTDEEIAEELGISLEEVQEALEAANayQLLSL-------DEPLEDGDDLL 159
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063733635 432 DGVGANNSRQPAL---LRLALDDVLDSLKPKESLVIRQRYgldgKGDRTLGEIAGNLNISREMVRKHEVKALMKLK 504
Cdd:COG1191   160 DLLESGDPEEELEheeLREALAEAIEQLPERERLVLSLYY----FEELTLKEIAEVLGVSESRVSRLHKKALARLR 231
PRK05658 PRK05658
RNA polymerase sigma factor RpoD; Validated
119-516 2.82e-29

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 235549 [Multi-domain]  Cd Length: 619  Bit Score: 121.82  E-value: 2.82e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 119 EDDVEDGGSKAKVSRRRKRKESGEEKKVVVRNnVKKEKRMSLDKRIAlKRNVQEKPVVASVDKKVTKRQQ---EEEKIER 195
Cdd:PRK05658  198 EEEEEDENDDSLAADESELPEKVLEKFKALAK-QYKKLRKAQEKKVE-GRLAQHKKYAKLREKLKEELKSlrlTSKQIDE 275
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 196 LVRDYSASND-IVSLDWKKMKIPPVL-------------SSTEHAWLFKLMQPMK----ALLEVKDVLQKSLGREpreAE 257
Cdd:PRK05658  276 LVEQLRDINKrVRGQERELLRLVERLkmprkdflklfqgNELDITWLEKEIASGKpwseFLVRVYDEIKKLQQEL---EA 352
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 258 IAGEINMTAGEVKK---KIEIG----RAARNKLIKHNLRLVLFVMNKYfhefTN-GPKFQDLCQAGMRGLITAIDRFEPK 329
Cdd:PRK05658  353 IEEETGLTIEELKEinrQISKGeakaRRAKKEMVEANLRLVISIAKKY----TNrGLQFLDLIQEGNIGLMKAVDKFEYR 428
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 330 RKFRLSTYGLFWIRHAIIRSMTTSNFT-RVPfglesvrV-------EIYKAKTELWFEMGRPPTEDEVVERLKITPERYR 401
Cdd:PRK05658  429 RGYKFSTYATWWIRQAITRSIADQARTiRIP-------VhmietinKLNRISRQMLQEIGREPTPEELAERLGMPEDKVR 501
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 402 EVLRAAKPVLSLNSkhSVTQEE------FI---NGITDVDGVGANNsrqpalLRLALDDVLDSLKPKESLVIRQRYGLDG 472
Cdd:PRK05658  502 KVLKIAKEPISLET--PIGDDEdshlgdFIedkNAELPIDAAIQES------LREATTDVLASLTPREAKVLRMRFGIDM 573
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....
gi 1063733635 473 KGDRTLGEIAGNLNISREMVRKHEVKALMKLKHQARVDYLRQYI 516
Cdd:PRK05658  574 NTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSRKLRSFL 617
PRK05657 PRK05657
RNA polymerase sigma factor RpoS; Validated
278-504 1.15e-23

RNA polymerase sigma factor RpoS; Validated


Pssm-ID: 235548 [Multi-domain]  Cd Length: 325  Bit Score: 101.57  E-value: 1.15e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 278 AARNKLIKHNLRLVLFVMNKYfhefTN-GPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRS-MTTSNF 355
Cdd:PRK05657   86 AARQRMIESNLRLVVKIAKRY----LNrGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAiMNQTRT 161
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 356 TRVPfglesVRV-----EIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSKHSV-TQEEFINGIT 429
Cdd:PRK05657  162 IRLP-----VHVvkelnVYLRAARELEHKLDHEPSAEEIAELLDKPVDDVSRMLALNERITSLDTPLGGdPEKSLLDILA 236
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063733635 430 DVDGVGANNSRQPALLRLALDDVLDSLKPKESLVIRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEVKALMKLK 504
Cdd:PRK05657  237 DEQENGPEDTTQDDDMKQSIVKWLFELNDKQREVLARRFGLLGYEAATLEDVAREIGLTRERVRQIQVEALRRLR 311
PRK05572 PRK05572
RNA polymerase sporulation sigma factor, SigF/SigG family;
268-506 7.61e-22

RNA polymerase sporulation sigma factor, SigF/SigG family;


Pssm-ID: 180137 [Multi-domain]  Cd Length: 252  Bit Score: 94.65  E-value: 7.61e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 268 EVKKKIEIGRA----ARNKLIKHNLRLVLFVMNKyfheFTN-GPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWI 342
Cdd:PRK05572   18 ENKELIKKSQDgdqeARDTLVEKNLRLVWSVVQR----FLNrGYEPDDLFQIGCIGLLKAVDKFDLSYDVKFSTYAVPMI 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 343 RHAIIRSMTTSNFTRVPFGLESVRVEIYKAKTELWFEMGRPPTEDEVVERLKITPEryrEVLRAAKPVLSLNSKHSVTQE 422
Cdd:PRK05572   94 IGEIQRFLRDDGTVKVSRSLKETANKIRKDKDELSKELGREPTIEELAEYLGVTPE---EVVLAQEASRSPQSIHETVHE 170
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 423 EFINGITDVDGVgANNSRQPALLRLALDDVLDSLKPKESLVIRQRYgldgKGDRTLGEIAGNLNISREMVRKHEVKALMK 502
Cdd:PRK05572  171 NDGDPITLLDQI-ADQSEEDWFDKIALKEAIRELDERERLIVYLRY----FKDKTQSEVAKRLGISQVQVSRLEKKILKQ 245

                  ....
gi 1063733635 503 LKHQ 506
Cdd:PRK05572  246 MKEK 249
PRK05803 PRK05803
RNA polymerase sporulation sigma factor SigK;
279-506 4.34e-18

RNA polymerase sporulation sigma factor SigK;


Pssm-ID: 180266 [Multi-domain]  Cd Length: 233  Bit Score: 83.46  E-value: 4.34e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 279 ARNKLIKHNLRLVLFVMNKYfhEFTnGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAI---IRSmttsnf 355
Cdd:PRK05803   50 ARNILIERNLRLVAHIVKKF--ENT-GEDVDDLISIGTIGLIKAIESFDAGKGTKLATYAARCIENEIlmhLRN------ 120
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 356 trvpfgLESVRVEIykaktelwfemgrpptedevverlkitperyrevlraakpvlSLNSKHSVTQEEfiNGITDVDGVG 435
Cdd:PRK05803  121 ------LKKTKKEV------------------------------------------SLQDPIGVDKEG--NEISLIDILG 150
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063733635 436 ANNSRQPALLRLALD-----DVLDSLKPKESLVIRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEVKALMKLKHQ 506
Cdd:PRK05803  151 SEEDDVIEQVELKMEveklyKKIDILDEREKEVIEMRYGLGNGKEKTQREIAKALGISRSYVSRIEKRALKKLFKE 226
PRK08215 PRK08215
RNA polymerase sporulation sigma factor SigG;
268-504 5.54e-16

RNA polymerase sporulation sigma factor SigG;


Pssm-ID: 181296 [Multi-domain]  Cd Length: 258  Bit Score: 77.68  E-value: 5.54e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 268 EVKKKIEIG-RAARNKLIKHNLRLVLFVMNKyfheFTN-GPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHA 345
Cdd:PRK08215   26 ELFERMQNGdKEAREKLINGNLRLVLSVIQR----FNNrGENVDDLFQVGCIGLMKAIDNFDLSQNVKFSTYAVPMIIGE 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 346 IIRSMTTSNFTRVPFGLESVRVEIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLnskhsvtQEEFI 425
Cdd:PRK08215  102 IRRYLRDNNPIRVSRSLRDIAYKALQVREKLINENSKEPTVEEIAKELEVPREEVVFALDAIQDPVSL-------FEPIY 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 426 NGITD----VDGVGANNSRQPALLR-LALDDVLDSLKPKESLVIRQRYgLDGKgdrTLGEIAGNLNISREMVRKHEVKAL 500
Cdd:PRK08215  175 HDGGDpiyvMDQISDEKNKDENWLEeIALKEAMKKLNDREKLILNLRF-FQGK---TQMEVAEEIGISQAQVSRLEKAAL 250

                  ....
gi 1063733635 501 MKLK 504
Cdd:PRK08215  251 KHMR 254
Sigma70_r3 pfam04539
Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the ...
366-439 2.59e-14

Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the sigma-factor. Region is not normally involved in the recognition of promoter DNA, but as some specific bacterial promoters containing an extended -10 promoter element, residues within region 3 play an important role. Region 3 primarily is involved in binding the core RNA polymerase in the holoenzyme.


Pssm-ID: 427997 [Multi-domain]  Cd Length: 78  Bit Score: 68.01  E-value: 2.59e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063733635 366 RVEIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSKHSVTQEEFING-ITDVDGVGANNS 439
Cdd:pfam04539   3 LNKIKRAQRELEQELGREPTPEEIAEELGLSPEKVREVLEAAREPVSLDTPVGEEEDGELGDlLEDDDIESPEEA 77
PRK05911 PRK05911
RNA polymerase sigma factor sigma-28; Reviewed
280-504 3.21e-14

RNA polymerase sigma factor sigma-28; Reviewed


Pssm-ID: 235644 [Multi-domain]  Cd Length: 257  Bit Score: 72.73  E-value: 3.21e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 280 RNKLIKHNLRLVLFVMNKYFHEFTNGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRSMTTSNFtrVP 359
Cdd:PRK05911   25 RDVLIEFYLPLVKNVAHRLISGMPSHVKTEDLYASGVEGLVRAVERFDPEKSRRFEGYALFLIKAAIIDDLRKQDW--VP 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 360 FGLESVRVEIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKP--VLSLNSKHS--------VTQEEFI---N 426
Cdd:PRK05911  103 RSVHQKANKLADAMDSLRQSLGKEPTDGELCEYLNISQQELSGWFSSARPalILSLNEEFPcqsddeagLALEERIadeR 182
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063733635 427 GITDVDGVgannSRQPALLRLAldDVLDSLKPKEslviRQRYGLDGKGDRTLGEIAGNLNISREMVRKHEVKALMKLK 504
Cdd:PRK05911  183 AETGYDVV----DKKEFSSILA--EAILALEEKE----RKVMALYYYEELVLKEIGKILGVSESRVSQIHSKALLKLR 250
rpoH2 PRK07500
RNA polymerase factor sigma-32; Reviewed
277-504 3.90e-14

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 236033 [Multi-domain]  Cd Length: 289  Bit Score: 72.76  E-value: 3.90e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 277 RAARNKLIKHNLRLVLFVMNKYFHeftNGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAI---------- 346
Cdd:PRK07500   39 EDALHRIISAHMRLVISMAGKFRR---FGLPMNDLIQEGYVGLLEAAARFEPDREVRFSTYATWWIRASIqdyilrnwsi 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 347 IRSMTTSNFTRVPFGLESVRVEIYKAKTELwfemGRPPTEDEVVERLKItPERYREVL--RAAKPVLSLNSKHSVTQEEf 424
Cdd:PRK07500  116 VRGGTSSAQKALFFNLRRLRARLAQADEEL----TKQEIHREIATALGV-SLSDVEMMdaRLSGPDASLNAPQSEEDEG- 189
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 425 inGITDVDGVgANNSRQPA----------LLRLALDDVLDSLKPKESLVIRQRYgLDGKGdRTLGEIAGNLNISREMVRK 494
Cdd:PRK07500  190 --RSERMDFL-VDDSPLPDeqvessidgeRRRRWLTQALQTLNERELRIIRERR-LREDG-ATLEALGEELGISKERVRQ 264
                         250
                  ....*....|
gi 1063733635 495 HEVKALMKLK 504
Cdd:PRK07500  265 IEARALEKLR 274
PRK07408 PRK07408
RNA polymerase sigma factor SigF; Reviewed
280-416 1.19e-12

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 180965 [Multi-domain]  Cd Length: 256  Bit Score: 68.02  E-value: 1.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 280 RNKLIKHNLRLVlfvmNKYFHEFTNGPK--FQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAI---IRSmtTSN 354
Cdd:PRK07408   27 RNQLVELNLGLV----RKEAHRWSNQCSepYEDLVQVGSLGLIRAIERFDPSKGHAFSSFAIPYIRGEIqhyLRD--KSP 100
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063733635 355 FTRVPFGLESVRVEIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAA--KPVLSLNSK 416
Cdd:PRK07408  101 TVRIPRRWQELQRQAKKVRQELRQELGRQPTDQEIAQALDISLEEWQEIKLALqnRTPLSLDAP 164
PRK08583 PRK08583
RNA polymerase sigma factor SigB; Validated
279-510 8.48e-12

RNA polymerase sigma factor SigB; Validated


Pssm-ID: 236306 [Multi-domain]  Cd Length: 257  Bit Score: 65.49  E-value: 8.48e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 279 ARNKLIKHNLRLVLFVMNKY-----FHEftngpkfqDLCQAGMRGLITAIDRFEPK--RKFRlstygLFWIRHAI----- 346
Cdd:PRK08583   30 AQEKLVKHYKNLVESLAYKYskgqsHHE--------DLVQVGMVGLLGAIRRYDPSfgRSFE-----AFAVPTIIgeikr 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 347 -IRSMTTSnfTRVPFGLESVRVEIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLRAAKPVLSLNSKHSVTQEEFI 425
Cdd:PRK08583   97 yLRDKTWS--VHVPRRIKELGPKIKKAVDELTTELQRSPKISEIADRLGVSEEEVLEAMEMGKSYQALSVDHSIEADSDG 174
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 426 NGITDVDGVGA-NNSRQPALLRLALDDVLDSLKPKESLVIRQRYgLDGKGDRTLGEIAGnlnISREMVRKHEVKALMKLK 504
Cdd:PRK08583  175 STVTLLDIVGQqEDGYELTEQRMILEKILPVLSDREKSIIQCTF-IENLSQKETGERLG---ISQMHVSRLQRQAIKKLR 250

                  ....*.
gi 1063733635 505 HQARVD 510
Cdd:PRK08583  251 EAAFLD 256
PRK06596 PRK06596
RNA polymerase factor sigma-32; Reviewed
278-504 9.87e-12

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 235838 [Multi-domain]  Cd Length: 284  Bit Score: 65.58  E-value: 9.87e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 278 AARnKLIKHNLRLVLFVMNKYFHEftnGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAI----IRSM--- 350
Cdd:PRK06596   49 AAK-QLVLSHLRFVVHIARGYRGY---GLPQADLIQEGNIGLMKAVKRFDPEVGVRLVSFAVHWIKAEIheyiLRNWriv 124
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 351 ---TTSNFTRVPFGLEsvrveiyKAKTEL-WFemgRPPTEDEVVERLKITPERYREV-LRAAKPVLSLN-------SKHS 418
Cdd:PRK06596  125 kvaTTKAQRKLFFNLR-------KAKKRLgWL---NPEEVEMVAEELGVSEEEVREMeSRLSGQDASLDapiddddEESG 194
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 419 VTQEEFINGITDVDGVGANNSRQpALLRLALDDVLDSLKPKESLVIRQRYGLDGKgdRTLGEIAGNLNISREMVRKHEVK 498
Cdd:PRK06596  195 APQDYLEDKSSDPADVLEEDNWE-DQRRALLADALEGLDERSRDIIEARWLDDDK--STLQELAAEYGVSAERVRQIEKN 271

                  ....*.
gi 1063733635 499 ALMKLK 504
Cdd:PRK06596  272 AMKKLK 277
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
283-348 1.90e-11

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 59.52  E-value: 1.90e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063733635 283 LIKHNLRLVLFVMNKYFHeftNGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIR 348
Cdd:pfam04542   1 LVERYLPLVYSLARRYLG---DGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIID 63
PRK06288 PRK06288
RNA polymerase sigma factor WhiG; Reviewed
280-504 4.75e-11

RNA polymerase sigma factor WhiG; Reviewed


Pssm-ID: 235770 [Multi-domain]  Cd Length: 268  Bit Score: 63.17  E-value: 4.75e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 280 RNKLIKHNLRLVLFVMNKYFHEFTNGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRSMTTSNFtrVP 359
Cdd:PRK06288   33 REYLILKYSPLVKYVAGRIAVGMPQNVEFDDLVSYGVFGLIDAIEKFDPEREIKFKTYAVTRIRGAIFDELRSIDW--IP 110
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 360 fglESVRV---EIYKAKTELWFEMGRPPTEDEVVERLKITPERYREVLR--AAKPVLSLNSKHSVTQEEfiNGITDVDGV 434
Cdd:PRK06288  111 ---RSVRQkarQIERAIAMLEARLGRTPSDEEIADELGISLEEYNSLLSklSGTSVVSLNDLWFGGDEG--DEVSLMDTL 185
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063733635 435 GANNSRQPALL------RLALDDVLDSLKPKESLVIRQRYgldgKGDRTLGEIAGNLNISREMVRKHEVKALMKLK 504
Cdd:PRK06288  186 ESPAALNPDEIaereeiKRVIVEAIKTLPEREKKVLILYY----YEDLTLKEIGKVLGVTESRISQLHTKAVLQLR 257
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
452-505 3.21e-10

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 55.51  E-value: 3.21e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1063733635 452 VLDSLKPKESLVIRQRYGldgkGDRTLGEIAGNLNISREMVRKHEVKALMKLKH 505
Cdd:pfam04545   1 ALASLPPRERQVLVLRYG----EGLTLEEIGERLGISRERVRQIEKRALRKLRK 50
PRK07670 PRK07670
FliA/WhiG family RNA polymerase sigma factor;
277-505 3.40e-09

FliA/WhiG family RNA polymerase sigma factor;


Pssm-ID: 181075 [Multi-domain]  Cd Length: 251  Bit Score: 57.36  E-value: 3.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 277 RAARNKLIKHNLRLVLFVMNKYFHEFTNGPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRSMTTSNft 356
Cdd:PRK07670   21 PDAADELIRRYMPLVHYHVQRISVGLPKSVSKDDLKSLGMLGLYDALEKFDPSRDLKFDTYASFRIRGAIIDGLRKED-- 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 357 RVPfglESVRVEIYK---AKTELWFEMGRPPTEDEVVERLKITPEryrEVLRAAKP-----VLSLNSKHSVTQEEFINGI 428
Cdd:PRK07670   99 WLP---RSMREKTKKveaAIEKLEQRYMRNVTPKEVAAELGMTEE---EVEATMNEgffanLLSIDEKTHDQDDGENVSV 172
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063733635 429 T--DVDGVGANNSRQPALLRLALDDVLDSLKPKESLVIRQRYgldgKGDRTLGEIAGNLNISREMVRKHEVKALMKLKH 505
Cdd:PRK07670  173 TirDDKTPTPEEKLLKEELIEELAEKIKQLSEKEQLVISLFY----KEELTLTEIGQVLNLSTSRISQIHSKALFKLKK 247
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
278-506 5.51e-09

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 55.05  E-value: 5.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 278 AARNKLIKHNLRLVLFVMNKYFhefTNGPKFQDLCQAGMRGLITAIDRFEPKRKFRlsTYGLFWIRHAIIRSMTTSNFTR 357
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYL---GDDADAEDLVQEAFLKLLEALDRFDPEGSFK--AWLFRIARNLILDYLRRKRRLR 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 358 VpfglesvrveiykaktelwfemgrppTEDEVVERLKITPERYREVLRAAkpvlslnskhsvtqeefingitdvdgvgan 437
Cdd:TIGR02937  76 R--------------------------ELDLLEELLDSDPSPEEELEQEE------------------------------ 99
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063733635 438 nsrqpalLRLALDDVLDSLKPKESLVIRQRYGldgkGDRTLGEIAGNLNISREMVRKHEVKALMKLKHQ 506
Cdd:TIGR02937 100 -------EREALREALEKLPEREREVLVLRYL----EGLSYKEIAEILGISVGTVKRRLKRARKKLREL 157
fliA PRK06986
flagellar biosynthesis sigma factor; Validated
310-464 1.64e-08

flagellar biosynthesis sigma factor; Validated


Pssm-ID: 235901 [Multi-domain]  Cd Length: 236  Bit Score: 55.24  E-value: 1.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 310 DLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAI---IRSMTTsnftrVPfglESVRV---EIYKAKTELWFEMGRP 383
Cdd:PRK06986   40 DLIQAGMIGLLEAARRYDGEQGASFETYAGQRIRGAMldeLRSLDW-----VP---RSVRRnarEVAQAIRQLEQELGRE 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 384 PTEDEVVERLKITPERYREVLRA--AKPVLSLNSKHSVTQEEFINGITDVDGVGANNSRQPAlLRLALDDVLDSLKPKES 461
Cdd:PRK06986  112 PTDTEVAEKLGLSLEEYREMLLDtnISQLFSIDELRGEHGDSILVTEDHQDEDPLQQLEDEE-LREALVEAIESLPEREQ 190

                  ...
gi 1063733635 462 LVI 464
Cdd:PRK06986  191 LVL 193
PRK08301 PRK08301
RNA polymerase sporulation sigma factor SigE;
271-337 2.80e-06

RNA polymerase sporulation sigma factor SigE;


Pssm-ID: 236228 [Multi-domain]  Cd Length: 234  Bit Score: 48.70  E-value: 2.80e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063733635 271 KKIEIGR-AARNKLIKHNLRLVLFVMNKyfheFTN-GPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTY 337
Cdd:PRK08301   44 NKLPKGDeAVRSLLIERNLRLVVYIARK----FENtGINIEDLISIGTIGLIKAVNTFNPEKKIKLATY 108
PRK07122 PRK07122
RNA polymerase sigma factor SigF; Reviewed
305-506 3.33e-06

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 168831 [Multi-domain]  Cd Length: 264  Bit Score: 48.62  E-value: 3.33e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 305 GPKFQDLCQAGMRGLITAIDRFEPKRKFRLSTYGLFWIRHAIIRSMTTSNFT-RVPFGLESVRVEIYKAKTELWFEMGRP 383
Cdd:PRK07122   64 GEPRDDLVQVARVGLVNAVNRFDVETGSDFVSFAVPTIMGEVRRHFRDNSWSvKVPRRLKELHLRLGRATAELSQRLGRA 143
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063733635 384 PTEDEVVERLKITPERYREVLRA--AKPVLSLNSKHSVTQEE---FINGITDVDGVGANNSRQPALLRLalddvLDSLKP 458
Cdd:PRK07122  144 PTASELAAELGMDREEVVEGLVAgsAYNTLSIDSGGGSGDDDaraIADTLGDVDAGLDQIENREALRPL-----LAALPE 218
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1063733635 459 KESLVIRQRYgldgKGDRTLGEIAGNLNISREMVRKHEVKALMKLKHQ 506
Cdd:PRK07122  219 RERTVLVLRF----FESMTQTQIAERVGISQMHVSRLLAKTLARLRDQ 262
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
446-504 2.17e-05

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 42.09  E-value: 2.17e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1063733635 446 RLALDDVLDSLKPKESLVIRQRYGldgkGDRTLGEIAGNLNISREMVRKHEVKALMKLK 504
Cdd:cd06171     1 RERLEEALDKLPEREREVILLRFG----EGLSYEEIAEILGISRSTVRQRLHRALKKLR 55
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
445-506 1.88e-03

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 39.59  E-value: 1.88e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063733635 445 LRLALDDVLDSLKPKESLVIRQRYgLDGKgdrTLGEIAGNLNISREMVRKHEVKALMKLKHQ 506
Cdd:COG1595   117 LLEALLAALERLPPRQREVLVLRY-LEGL---SYAEIAEILGISEGTVKSRLSRARKKLREA 174
Sigma70_r3 pfam04539
Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the ...
238-280 2.34e-03

Sigma-70 region 3; Region 3 forms a discrete compact three helical domain within the sigma-factor. Region is not normally involved in the recognition of promoter DNA, but as some specific bacterial promoters containing an extended -10 promoter element, residues within region 3 play an important role. Region 3 primarily is involved in binding the core RNA polymerase in the holoenzyme.


Pssm-ID: 427997 [Multi-domain]  Cd Length: 78  Bit Score: 36.81  E-value: 2.34e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 1063733635 238 LLEVKDVLQKSLGREPREAEIAGEINMTAGEVKKKIEIGRAAR 280
Cdd:pfam04539   6 IKRAQRELEQELGREPTPEEIAEELGLSPEKVREVLEAAREPV 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH