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Conserved domains on  [gi|1063726992|ref|NP_001329708|]
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plant intracellular ras group-related LRR 4 [Arabidopsis thaliana]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
195-516 1.60e-39

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 148.93  E-value: 1.60e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 195 TLTTGNDGEKLSLIKLASLIEVSAKKATQEINLQNKLTEQLEWLPDSLGKLSSLTSLDLSENHIVVLPNTIGGLSSLTKL 274
Cdd:COG4886    62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKEL 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 275 DLHSNRIGQLPESIGELLNLVYLNLGSNQLSSLPSAFSRLVRLEELDLSCNNLPILPESIGSLVSLKKLDVETNDIEEIP 354
Cdd:COG4886   142 DLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLP 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 355 YSIGGCSSLIELRADYNKLKALPEaIGKITTLEILSVRYNNIRQLPTTmSSLASLKELDVSFNELESVpeslcfatTLVK 434
Cdd:COG4886   222 EPLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELDLSNNQLTDLPPL-ANLTNLKTLDLSNNQLTDL--------KLKE 291

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 435 LNIGNNFADMVSLPRSIGNLEMLEELDISNNQIRVLPDSFKMLTKLRVFRAQENPLHIPPRDIAEKGPQVLFSLSVSLYV 514
Cdd:COG4886   292 LELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGL 371


                  ..
gi 1063726992 515 IM 516
Cdd:COG4886   372 LG 373
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
195-516 1.60e-39

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 148.93  E-value: 1.60e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 195 TLTTGNDGEKLSLIKLASLIEVSAKKATQEINLQNKLTEQLEWLPDSLGKLSSLTSLDLSENHIVVLPNTIGGLSSLTKL 274
Cdd:COG4886    62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKEL 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 275 DLHSNRIGQLPESIGELLNLVYLNLGSNQLSSLPSAFSRLVRLEELDLSCNNLPILPESIGSLVSLKKLDVETNDIEEIP 354
Cdd:COG4886   142 DLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLP 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 355 YSIGGCSSLIELRADYNKLKALPEaIGKITTLEILSVRYNNIRQLPTTmSSLASLKELDVSFNELESVpeslcfatTLVK 434
Cdd:COG4886   222 EPLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELDLSNNQLTDLPPL-ANLTNLKTLDLSNNQLTDL--------KLKE 291

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 435 LNIGNNFADMVSLPRSIGNLEMLEELDISNNQIRVLPDSFKMLTKLRVFRAQENPLHIPPRDIAEKGPQVLFSLSVSLYV 514
Cdd:COG4886   292 LELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGL 371


                  ..
gi 1063726992 515 IM 516
Cdd:COG4886   372 LG 373
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
272-484 2.00e-18

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 88.99  E-value: 2.00e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 272 TKLDLHSNRIGQLPESIGEllNLVYLNLGSNQLSSLPSAFSrlVRLEELDLSCNNLPILPESIGSlvSLKKLDVETNDIE 351
Cdd:PRK15370  181 TELRLKILGLTTIPACIPE--QITTLILDNNELKSLPENLQ--GNIKTLYANSNQLTSIPATLPD--TIQEMELSINRIT 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 352 EIPYSIGgcSSLIELRADYNKLKALPEAIGKitTLEILSVRYNNIRQLPTTMSSlaSLKELDVSFNELESVPESLcfATT 431
Cdd:PRK15370  255 ELPERLP--SALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSLTALPETL--PPG 326

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1063726992 432 LVKLNIGNNfaDMVSLPRSIGnlEMLEELDISNNQIRVLPDSF-KMLTKLRVFR 484
Cdd:PRK15370  327 LKTLEAGEN--ALTSLPASLP--PELQVLDVSKNQITVLPETLpPTITTLDVSR 376
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 268-490 6.36e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 59.41  E-value: 6.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 268 LSSLTKLDLHSNRIgqlpESIGELL---NLVYLNLGSNQLSSLPSaFSRLVRLEELDLSCNNLPILpESIGSLVSLKKLD 344
Cdd:cd21340     1 LKRITHLYLNDKNI----TKIDNLSlckNLKVLYLYDNKITKIEN-LEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLY 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 345 VETNDIEEIPySIGGCSSLIELRADYNKLkALPEAIgkitTLEilsvrynnirqlPTTMSSLA-SLKELDVSfnelesvp 423
Cdd:cd21340    75 LGGNRISVVE-GLENLTNLEELHIENQRL-PPGEKL----TFD------------PRSLAALSnSLRVLNIS-------- 128

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 424 eslcfattlvklniGNNFADMvslpRSIGNLEMLEELDISNNQIRVLPDSFKML---TKLRVFRAQENPL 490
Cdd:cd21340   129 --------------GNNIDSL----EPLAPLRNLEQLDASNNQISDLEELLDLLsswPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
269-327 2.69e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 53.30  E-value: 2.69e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063726992 269 SSLTKLDLHSNRIGQL-PESIGELLNLVYLNLGSNQLSSL-PSAFSRLVRLEELDLSCNNL 327
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
195-516 1.60e-39

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 148.93  E-value: 1.60e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 195 TLTTGNDGEKLSLIKLASLIEVSAKKATQEINLQNKLTEQLEWLPDSLGKLSSLTSLDLSENHIVVLPNTIGGLSSLTKL 274
Cdd:COG4886    62 LSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKEL 141

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 275 DLHSNRIGQLPESIGELLNLVYLNLGSNQLSSLPSAFSRLVRLEELDLSCNNLPILPESIGSLVSLKKLDVETNDIEEIP 354
Cdd:COG4886   142 DLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLP 221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 355 YSIGGCSSLIELRADYNKLKALPEaIGKITTLEILSVRYNNIRQLPTTmSSLASLKELDVSFNELESVpeslcfatTLVK 434
Cdd:COG4886   222 EPLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELDLSNNQLTDLPPL-ANLTNLKTLDLSNNQLTDL--------KLKE 291

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 435 LNIGNNFADMVSLPRSIGNLEMLEELDISNNQIRVLPDSFKMLTKLRVFRAQENPLHIPPRDIAEKGPQVLFSLSVSLYV 514
Cdd:COG4886   292 LELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGL 371


                  ..
gi 1063726992 515 IM 516
Cdd:COG4886   372 LG 373
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
200-490 2.12e-39

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 148.54  E-value: 2.12e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 200 NDGEKLSLIKLASLIEVSAKKATQEINLQNKLTEQLEWLPDSLGKLSSLTSLDLSENHIVVLPNTIGGLSSLTKLDLHSN 279
Cdd:COG4886     4 LLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 280 RIGQLPESIGELLNLVYLNLGSNQlsslpsAFSRLVRLEELDLSCNNLPILPESIGSLVSLKKLDVETNDIEEIPYSIGG 359
Cdd:COG4886    84 LLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGN 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 360 CSSLIELRADYNKLKALPEAIGKITTLEILSVRYNNIRQLPTTMSSLASLKELDVSFNELESVPESLCFATTLVKLNIGN 439
Cdd:COG4886   158 LTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSN 237

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1063726992 440 NfaDMVSLPrSIGNLEMLEELDISNNQIRVLPDSFKmLTKLRVFRAQENPL 490
Cdd:COG4886   238 N--QLTDLP-ELGNLTNLEELDLSNNQLTDLPPLAN-LTNLKTLDLSNNQL 284
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
268-498 6.74e-21

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 95.00  E-value: 6.74e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 268 LSSLTKLDLHSNRIGQLPESIGELLNLVYLNLGSNQLSSLPSAFSRLVRLEELDLSCNNLPILPESIGSLVSLKKLDVET 347
Cdd:COG4886     3 LLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 348 NDIEEIPYSIGGCSSLIELRADYNklkalpEAIGKITTLEILSVRYNNIRQLPTTMSSLASLKELDVSFNELESVPESLC 427
Cdd:COG4886    83 SLLLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLG 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063726992 428 FATTLVKLNIGNNfaDMVSLPRSIGNLEMLEELDISNNQIRVLPDSFKMLTKLRVFRAQENPLHIPPRDIA 498
Cdd:COG4886   157 NLTNLKSLDLSNN--QLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLA 225
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
272-484 2.00e-18

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 88.99  E-value: 2.00e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 272 TKLDLHSNRIGQLPESIGEllNLVYLNLGSNQLSSLPSAFSrlVRLEELDLSCNNLPILPESIGSlvSLKKLDVETNDIE 351
Cdd:PRK15370  181 TELRLKILGLTTIPACIPE--QITTLILDNNELKSLPENLQ--GNIKTLYANSNQLTSIPATLPD--TIQEMELSINRIT 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 352 EIPYSIGgcSSLIELRADYNKLKALPEAIGKitTLEILSVRYNNIRQLPTTMSSlaSLKELDVSFNELESVPESLcfATT 431
Cdd:PRK15370  255 ELPERLP--SALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSLTALPETL--PPG 326

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1063726992 432 LVKLNIGNNfaDMVSLPRSIGnlEMLEELDISNNQIRVLPDSF-KMLTKLRVFR 484
Cdd:PRK15370  327 LKTLEAGEN--ALTSLPASLP--PELQVLDVSKNQITVLPETLpPTITTLDVSR 376
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 261-467 6.11e-18

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 87.60  E-value: 6.11e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 261 LPNTIGGLSSLTKLDL-HSNRIGQLPESIGELLNLVYLNLGSNQLS-SLPSAFSRLVRLEELDLSCNNLP-ILPESIGSL 337
Cdd:PLN00113  228 IPYEIGGLTSLNHLDLvYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSgEIPELVIQL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 338 VSLKKLDVETNDIE-EIPYSIGGCSSLIELRADYNKLKA-LPEAIGKITTLEILSVRYNNIR-QLPTTMSSLASLKELDV 414
Cdd:PLN00113  308 QNLEILHLFSNNFTgKIPVALTSLPRLQVLQLWSNKFSGeIPKNLGKHNNLTVLDLSTNNLTgEIPEGLCSSGNLFKLIL 387

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1063726992 415 SFNELES-VPESL--CFATTLVKLNiGNNFADmvSLPRSIGNLEMLEELDISNNQI 467
Cdd:PLN00113  388 FSNSLEGeIPKSLgaCRSLRRVRLQ-DNSFSG--ELPSEFTKLPLVYFLDISNNNL 440
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 229-493 1.35e-16

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 83.36  E-value: 1.35e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 229 NKLTEQLewlPDSLGKLSSLTSLDLSENHIV-VLPNTIGGLSSLTKLDLHSNRI-GQLPESIGELLNLVYLNLGSNQLS- 305
Cdd:PLN00113  246 NNLTGPI---PSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLsGEIPELVIQLQNLEILHLFSNNFTg 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 306 SLPSAFSRLVRLE------------------------ELDLSCNNLP-ILPESIGSLVSLKKLDVETNDIE-EIPYSIGG 359
Cdd:PLN00113  323 KIPVALTSLPRLQvlqlwsnkfsgeipknlgkhnnltVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEgEIPKSLGA 402

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 360 CSSLIELRADYNKLKA-LPEAIGKITTLEILSVRYNNIR-QLPTTMSSLASLKELDVSFNE-LESVPESLCfATTLVKLN 436
Cdd:PLN00113  403 CRSLRRVRLQDNSFSGeLPSEFTKLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKfFGGLPDSFG-SKRLENLD 481

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063726992 437 IGNN-FADMVslPRSIGNLEMLEELDISNNQIR-VLPDSFKMLTKLRVFRAQENPL--HIP 493
Cdd:PLN00113  482 LSRNqFSGAV--PRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLsgQIP 540
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 261-480 1.10e-15

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 80.28  E-value: 1.10e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 261 LPNTIGGLSSLTKLDLHSN-RIGQLPESIGELLNLVYLNLGSNQLS-------------------------SLPSAFSRL 314
Cdd:PLN00113  156 IPNDIGSFSSLKVLDLGGNvLVGKIPNSLTNLTSLEFLTLASNQLVgqiprelgqmkslkwiylgynnlsgEIPYEIGGL 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 315 VRLEELDLSCNNL--PIlPESIGSLVSLKKLDVETNDIE-EIPYSIGGCSSLIELRADYNKLKA-LPEAIGKITTLEILS 390
Cdd:PLN00113  236 TSLNHLDLVYNNLtgPI-PSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSGeIPELVIQLQNLEILH 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 391 VRYNNIR-QLPTTMSSLASLK------------------------ELDVSFNELES-VPESLCFATTLVKLNIGNNFADM 444
Cdd:PLN00113  315 LFSNNFTgKIPVALTSLPRLQvlqlwsnkfsgeipknlgkhnnltVLDLSTNNLTGeIPEGLCSSGNLFKLILFSNSLEG 394

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1063726992 445 vSLPRSIGNLEMLEELDISNNQIR-VLPDSFkmlTKL 480
Cdd:PLN00113  395 -EIPKSLGACRSLRRVRLQDNSFSgELPSEF---TKL 427
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
228-426 1.23e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 77.04  E-value: 1.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 228 QNKLTEQLEWLPDSLgklsslTSLDLSENHIVVLPNTIGglSSLTKLDLHSNRIGQLPESIGEllNLVYLNLGSNQLSSL 307
Cdd:PRK15370  229 SNQLTSIPATLPDTI------QEMELSINRITELPERLP--SALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTL 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 308 PSAFSRlvRLEELDLSCNNLPILPESIGslVSLKKLDVETNDIEEIPYSIGgcSSLIELRADYNKLKALPEAIGKitTLE 387
Cdd:PRK15370  299 PAHLPS--GITHLNVQSNSLTALPETLP--PGLKTLEAGENALTSLPASLP--PELQVLDVSKNQITVLPETLPP--TIT 370

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1063726992 388 ILSVRYNNIRQLPTTMSslASLKELDVSFNELESVPESL 426
Cdd:PRK15370  371 TLDVSRNALTNLPENLP--AALQIMQASRNNLVRLPESL 407
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
223-408 5.71e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 74.73  E-value: 5.71e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 223 QEINLQ-NKLTEQLEWLPDSLgklsslTSLDLSENHIVVLPNTIGglSSLTKLDLHSNRIGQLPESIGEllNLVYLNLGS 301
Cdd:PRK15370  244 QEMELSiNRITELPERLPSAL------QSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLPS--GITHLNVQS 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 302 NQLSSLPSAFSrlVRLEELDLSCNNLPILPESIGSlvSLKKLDVETNDIEEIPYSIGgcSSLIELRADYNKLKALPEAIG 381
Cdd:PRK15370  314 NSLTALPETLP--PGLKTLEAGENALTSLPASLPP--ELQVLDVSKNQITVLPETLP--PTITTLDVSRNALTNLPENLP 387

                         170       180
                  ....*....|....*....|....*..
gi 1063726992 382 kiTTLEILSVRYNNIRQLPTTMSSLAS 408
Cdd:PRK15370  388 --AALQIMQASRNNLVRLPESLPHFRG 412
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 269-508 6.85e-13

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 71.42  E-value: 6.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 269 SSLTKLDLHSNRI-GQLPESIGELLNLVYLNLGSNQLS--------------------------SLPSAFsrLVRLEELD 321
Cdd:PLN00113   69 SRVVSIDLSGKNIsGKISSAIFRLPYIQTINLSNNQLSgpipddifttssslrylnlsnnnftgSIPRGS--IPNLETLD 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 322 LSCNNLP-ILPESIGSLVSLKKLDVETNDIE-EIPYSIGGCSSLIELRADYNKLKA-LPEAIGKITTLEILSVRYNNIR- 397
Cdd:PLN00113  147 LSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVGqIPRELGQMKSLKWIYLGYNNLSg 226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 398 QLPTTMSSLASLKELDVSFNELE-SVPESLCFATTLVKLNI-GNNFADmvSLPRSIGNLEMLEELDISNNQIR-VLPDSF 474
Cdd:PLN00113  227 EIPYEIGGLTSLNHLDLVYNNLTgPIPSSLGNLKNLQYLFLyQNKLSG--PIPPSIFSLQKLISLDLSDNSLSgEIPELV 304

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1063726992 475 KMLTKLRVfraqenpLHIPPRDIAEKGPQVLFSL 508
Cdd:PLN00113  305 IQLQNLEI-------LHLFSNNFTGKIPVALTSL 331
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 238-440 1.70e-10

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 63.71  E-value: 1.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 238 LPDSLGKLSSLTSLDLSENHIV-VLPNTIGGLSSLTKLDLHSNRI-GQLPESIGELLNLVYLNLGSNQLS-SLPSAFsRL 314
Cdd:PLN00113  396 IPKSLGACRSLRRVRLQDNSFSgELPSEFTKLPLVYFLDISNNNLqGRINSRKWDMPSLQMLSLARNKFFgGLPDSF-GS 474

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 315 VRLEELDLSCNNLP-ILPESIGSLVSLKKLDVETNDIE-EIPYSIGGCSSLIELRADYNKLKAlpeaigkittleilsvr 392
Cdd:PLN00113  475 KRLENLDLSRNQFSgAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLSG----------------- 537

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1063726992 393 ynnirQLPTTMSSLASLKELDVSFNELE-SVPESLCFATTLVKLNIGNN 440
Cdd:PLN00113  538 -----QIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHN 581
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 268-490 6.36e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 59.41  E-value: 6.36e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 268 LSSLTKLDLHSNRIgqlpESIGELL---NLVYLNLGSNQLSSLPSaFSRLVRLEELDLSCNNLPILpESIGSLVSLKKLD 344
Cdd:cd21340     1 LKRITHLYLNDKNI----TKIDNLSlckNLKVLYLYDNKITKIEN-LEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLY 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 345 VETNDIEEIPySIGGCSSLIELRADYNKLkALPEAIgkitTLEilsvrynnirqlPTTMSSLA-SLKELDVSfnelesvp 423
Cdd:cd21340    75 LGGNRISVVE-GLENLTNLEELHIENQRL-PPGEKL----TFD------------PRSLAALSnSLRVLNIS-------- 128

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 424 eslcfattlvklniGNNFADMvslpRSIGNLEMLEELDISNNQIRVLPDSFKML---TKLRVFRAQENPL 490
Cdd:cd21340   129 --------------GNNIDSL----EPLAPLRNLEQLDASNNQISDLEELLDLLsswPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
269-327 2.69e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 53.30  E-value: 2.69e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063726992 269 SSLTKLDLHSNRIGQL-PESIGELLNLVYLNLGSNQLSSL-PSAFSRLVRLEELDLSCNNL 327
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
271-490 7.10e-09

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 58.63  E-value: 7.10e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 271 LTKLDLHSNRIGQLPESIGELLNLvylNLGSNQLSSLPSAFSRLVRLEELDLSCNNLPILPEsigslvSLKKLDVETNDI 350
Cdd:PRK15387  244 LRTLEVSGNQLTSLPVLPPGLLEL---SIFSNPLTHLPALPSGLCKLWIFGNQLTSLPVLPP------GLQELSVSDNQL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 351 EEIPysiGGCSSLIELRADYNKLKALPEAigkITTLEILSVRYNNIRQLPTTMSSL-----------------ASLKELD 413
Cdd:PRK15387  315 ASLP---ALPSELCKLWAYNNQLTSLPTL---PSGLQELSVSDNQLASLPTLPSELyklwaynnrltslpalpSGLKELI 388

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063726992 414 VSFNELESVPeslCFATTLVKLNI-GNNFADMVSLPRSignlemLEELDISNNQIRVLPDSFKMLTKLRVFRAQENPL 490
Cdd:PRK15387  389 VSGNRLTSLP---VLPSELKELMVsGNRLTSLPMLPSG------LLSLSVYRNQLTRLPESLIHLSSETTVNLEGNPL 457
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 254-435 1.39e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 55.18  E-value: 1.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 254 SENHIVVLPNtIGGLSSLTKLDLHSNRIGQLpESIGELLNLVYLNLGSNQLSSLPSaFSRLVRLEELDLSCNNLPILpES 333
Cdd:cd21340    10 NDKNITKIDN-LSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIEN-LENLVNLKKLYLGGNRISVV-EG 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 334 IGSLVSLKKLDVETNDIEEipysigGCSSLIELRAdynkLKALPEaigkitTLEILSVRYNNIRQLpTTMSSLASLKELD 413
Cdd:cd21340    86 LENLTNLEELHIENQRLPP------GEKLTFDPRS----LAALSN------SLRVLNISGNNIDSL-EPLAPLRNLEQLD 148

                         170       180
                  ....*....|....*....|..
gi 1063726992 414 VSFNELESVPESLCFATTLVKL 435
Cdd:cd21340   149 ASNNQISDLEELLDLLSSWPSL 170
LRR_8 pfam13855
Leucine rich repeat;
293-350 2.10e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.60  E-value: 2.10e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 293 NLVYLNLGSNQLSSL-PSAFSRLVRLEELDLSCNNLPIL-PESIGSLVSLKKLDVETNDI 350
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 270-464 8.79e-08

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 55.27  E-value: 8.79e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992  270 SLTKLDLHSNRIGQLPESIGELLNLVYLNL-GSNQLSSLPSaFSRLVRLEELDLS-CNNLPILPESIGSLVSLKKLDVET 347
Cdd:PLN03210   612 NLVKLQMQGSKLEKLWDGVHSLTGLRNIDLrGSKNLKEIPD-LSMATNLETLKLSdCSSLVELPSSIQYLNKLEDLDMSR 690

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992  348 ND-IEEIPYSI----------GGCSslielradynKLKALPEAIGKITTLEILSVrynNIRQLPTTMS-------SLASL 409
Cdd:PLN03210   691 CEnLEILPTGInlkslyrlnlSGCS----------RLKSFPDISTNISWLDLDET---AIEEFPSNLRlenldelILCEM 757

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1063726992  410 KELDVSFNELESVPESLCFATTLVKLNIGNNfADMVSLPRSIGNLEMLEELDISN 464
Cdd:PLN03210   758 KSEKLWERVQPLTPLMTMLSPSLTRLFLSDI-PSLVELPSSIQNLHKLEHLEIEN 811
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
297-499 1.85e-07

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 54.01  E-value: 1.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 297 LNLGSNQLSSLPSAF-SRLVRLEELDLSCNNLPILPESigslvsLKKLDVETNDIEEIPYSIGGcssLIELRADYNKLKA 375
Cdd:PRK15387  206 LNVGESGLTTLPDCLpAHITTLVIPDNNLTSLPALPPE------LRTLEVSGNQLTSLPVLPPG---LLELSIFSNPLTH 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 376 LPEAIGKITTLEILSVRYNNIRQLPttmsslASLKELDVSFNELESVPeslCFATTLVKLNIGNNfaDMVSLPRSIGNLE 455
Cdd:PRK15387  277 LPALPSGLCKLWIFGNQLTSLPVLP------PGLQELSVSDNQLASLP---ALPSELCKLWAYNN--QLTSLPTLPSGLQ 345

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1063726992 456 mleELDISNNQIRVLPDSFKMLTKLRVFRAQENPLHIPPRDIAE 499
Cdd:PRK15387  346 ---ELSVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPSGLKE 386
PLN03150 PLN03150
hypothetical protein; Provisional
 282-359 2.06e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 53.67  E-value: 2.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 282 GQLPESIGELLNLVYLNLGSNQL-SSLPSAFSRLVRLEELDLSCNNLP-ILPESIGSLVSLKKLDVETNDIE-EIPYSIG 358
Cdd:PLN03150  432 GFIPNDISKLRHLQSINLSGNSIrGNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSgRVPAALG 511


                  .
gi 1063726992 359 G 359
Cdd:PLN03150  512 G 512
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 256-348 1.30e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.40  E-value: 1.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 256 NHIVVLPNtIGGLSSLTKLDLHSNRIGQL----------------------------PESIGELLN-LVYLNLGSNQLSS 306
Cdd:cd21340    56 NQIEKIEN-LENLVNLKKLYLGGNRISVVeglenltnleelhienqrlppgekltfdPRSLAALSNsLRVLNISGNNIDS 134

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1063726992 307 LpSAFSRLVRLEELDLSCNNL----PILpESIGSLVSLKKLDVETN 348
Cdd:cd21340   135 L-EPLAPLRNLEQLDASNNQIsdleELL-DLLSSWPSLRELDLTGN 178
PLN03150 PLN03150
hypothetical protein; Provisional
 238-316 2.78e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 50.20  E-value: 2.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 238 LPDSLGKLSSLTSLDLSENHIV-VLPNTIGGLSSLTKLDLHSNRI-GQLPESIGELLNLVYLNLGSNQLSS-LPSAF-SR 313
Cdd:PLN03150  434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFnGSIPESLGQLTSLRILNLNGNSLSGrVPAALgGR 513


                  ...
gi 1063726992 314 LVR 316
Cdd:PLN03150  514 LLH 516
PLN03150 PLN03150
hypothetical protein; Provisional
 376-441 5.90e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 49.04  E-value: 5.90e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063726992 376 LPEAIGKITTLEILSVRYNNIR-QLPTTMSSLASLKELDVSFNELE-SVPESLCFATTLVKLNIGNNF 441
Cdd:PLN03150  434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNS 501
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
269-419 1.01e-05

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 48.23  E-value: 1.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 269 SSLTKLDLHSNRIGQLPESIGELLNLvylNLGSNQLSSLPSAFSRLVRLEELDLSCNNLPILPEsigslvSLKKLDVETN 348
Cdd:PRK15387  322 SELCKLWAYNNQLTSLPTLPSGLQEL---SVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPS------GLKELIVSGN 392

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063726992 349 DIEEIPYSIggcSSLIELRADYNKLKALPEAIGKITTleiLSVRYNNIRQLPTTMSSLASLKELDVSFNEL 419
Cdd:PRK15387  393 RLTSLPVLP---SELKELMVSGNRLTSLPMLPSGLLS---LSVYRNQLTRLPESLIHLSSETTVNLEGNPL 457
PLN03150 PLN03150
hypothetical protein; Provisional
 330-394 1.07e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 48.27  E-value: 1.07e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1063726992 330 LPESIGSLVSLKKLDVETNDIE-EIPYSIGGCSSLIELRADYNKLK-ALPEAIGKITTLEILSVRYN 394
Cdd:PLN03150  434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGN 500
LRR_8 pfam13855
Leucine rich repeat;
256-304 4.68e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.27  E-value: 4.68e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1063726992 256 NHIVVL-PNTIGGLSSLTKLDLHSNRIGQL-PESIGELLNLVYLNLGSNQL 304
Cdd:pfam13855  11 NRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 131-440 4.68e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 42.85  E-value: 4.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 131 PLPPATTTAARSDSQSSLNFSERAPVRPKDMVSRDDSFVTKSKPSSLysdgFAAPPRRPQI---LDSTLTT--GNDGE-- 203
Cdd:COG5238    88 QLLVVDWEGAEEVSPVALAETATAVATPPPDLRRIMAKTLEDSLILY----LALPRRINLIqvlKDPLGGNavHLLGLaa 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 204 KLSLIKLASLIEVSAKKATQEINLQNKLTEQ--LEWLPDSLGKLSSLTSLDLSENHI-----VVLPNTIGGLSSLTKLDL 276
Cdd:COG5238   164 RLGLLAAISMAKALQNNSVETVYLGCNQIGDegIEELAEALTQNTTVTTLWLKRNPIgdegaEILAEALKGNKSLTTLDL 243

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 277 HSNRIG-QLPESIGELL----NLVYLNLGSNQLS-----SLPSAFSRLVRLEELDLSCNNlpilpesigslvslkkldve 346
Cdd:COG5238   244 SNNQIGdEGVIALAEALknntTVETLYLSGNQIGaegaiALAKALQGNTTLTSLDLSVNR-------------------- 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 347 tndieeipysIGGCSSLielradynklkALPEAIGKITTLEILSVRYNNIRQ-----LPTTMSSLASLKELDVSFNEL-- 419
Cdd:COG5238   304 ----------IGDEGAI-----------ALAEGLQGNKTLHTLNLAYNGIGAqgaiaLAKALQENTTLHSLDLSDNQIgd 362

                         330       340
                  ....*....|....*....|....
gi 1063726992 420 ---ESVPESLCFATTLVKLNIGNN 440
Cdd:COG5238   363 egaIALAKYLEGNTTLRELNLGKN 386
LRR_8 pfam13855
Leucine rich repeat;
384-467 1.28e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 1.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 384 TTLEILSVRYNNIRQL-PTTMSSLASLKELDVSFNELESVPeslcfattlvklnignnfadmvslPRSIGNLEMLEELDI 462
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLS------------------------PGAFSGLPSLRYLDL 56


                  ....*
gi 1063726992 463 SNNQI 467
Cdd:pfam13855  57 SGNRL 61
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 269-419 1.75e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 40.80  E-value: 1.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 269 SSLTKLDLHSNRIGQLP-----ESIGEL-LNLVYLNLGSNQLSS-----LPSAFSRLVRLEELDLSCNNL-----PILPE 332
Cdd:cd00116   108 SSLQELKLNNNGLGDRGlrllaKGLKDLpPALEKLVLGRNRLEGasceaLAKALRANRDLKELNLANNGIgdagiRALAE 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063726992 333 SIGSLVSLKKLDVETNDIEEIpysigGCSSLIELRADYNKLKAL----------------PEAIGKITTLEILSVRYNNI 396
Cdd:cd00116   188 GLKANCNLEVLDLNNNGLTDE-----GASALAETLASLKSLEVLnlgdnnltdagaaalaSALLSPNISLLTLSLSCNDI 262

                         170       180
                  ....*....|....*....|....*...
gi 1063726992 397 -----RQLPTTMSSLASLKELDVSFNEL 419
Cdd:cd00116   263 tddgaKDLAEVLAEKESLLELDLRGNKF 290
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 293-327 2.08e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 36.07  E-value: 2.08e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1063726992 293 NLVYLNLGSNQLSSLPsAFSRLVRLEELDLSCNNL 327
Cdd:pfam12799   2 NLEVLDLSNNQITDIP-PLAKLPNLETLDLSGNNK 35
LRR_8 pfam13855
Leucine rich repeat;
430-490 3.04e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 3.04e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1063726992 430 TTLVKLNIGNNFADMVSlPRSIGNLEMLEELDISNNQIRVL-PDSFKMLTKLRVFRAQENPL 490
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLD-DGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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