fatty acid hydroxylase 2 [Arabidopsis thaliana]
sterol desaturase family protein; fatty acid 2-hydroxylase( domain architecture ID 10010789)
sterol desaturase family protein is an oxidoreductase, similar to C-5 sterol desaturase, which catalyzes a dehydrogenation reaction to introduce a C5-6 double bond into substrates such as lathosterol and the B ring of ergosterol| fatty acid 2-hydroxylase is an integral membrane involved in processes such as cholesterol biosynthesis or biosynthesis of plant cuticular wax. It catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids, for example, and contains an N-terminal cytochrome b5-like heme/steroid binding domain
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
PLN02434 | PLN02434 | fatty acid hydroxylase |
1-237 | 2.03e-156 | ||||
fatty acid hydroxylase : Pssm-ID: 178053 [Multi-domain] Cd Length: 237 Bit Score: 433.30 E-value: 2.03e-156
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Name | Accession | Description | Interval | E-value | ||||
PLN02434 | PLN02434 | fatty acid hydroxylase |
1-237 | 2.03e-156 | ||||
fatty acid hydroxylase Pssm-ID: 178053 [Multi-domain] Cd Length: 237 Bit Score: 433.30 E-value: 2.03e-156
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FA_hydroxylase | pfam04116 | Fatty acid hydroxylase; This entry includes fatty acid and carotene hydroxylases and sterol ... |
87-226 | 7.28e-15 | ||||
Fatty acid hydroxylase; This entry includes fatty acid and carotene hydroxylases and sterol desaturases. Beta-carotene hydroxylase is involved in zeaxanthin synthesis by hydroxylating beta-carotene, but the enzyme may be involved in other pathways. This family includes C-5 sterol desaturase and C-4 sterol methyl oxidase. Members of this family are involved in cholesterol biosynthesis and biosynthesis a plant cuticular wax. These enzymes contain two copies of a HXHH motif which coordinate two irons at the catalytic centre. Members of this family are ER integral membrane proteins that share a novel mushroom-shaped fold consisting of four transmembrane (TM1-TM4) helices that anchor them to the membrane capped by a cytosolic domain containing the unique histidine- coordinating di metal centre. Pssm-ID: 397991 Cd Length: 134 Bit Score: 69.00 E-value: 7.28e-15
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ERG3 | COG3000 | Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid ... |
87-226 | 5.49e-05 | ||||
Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]; Pssm-ID: 442238 Cd Length: 158 Bit Score: 42.23 E-value: 5.49e-05
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Name | Accession | Description | Interval | E-value | ||||
PLN02434 | PLN02434 | fatty acid hydroxylase |
1-237 | 2.03e-156 | ||||
fatty acid hydroxylase Pssm-ID: 178053 [Multi-domain] Cd Length: 237 Bit Score: 433.30 E-value: 2.03e-156
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FA_hydroxylase | pfam04116 | Fatty acid hydroxylase; This entry includes fatty acid and carotene hydroxylases and sterol ... |
87-226 | 7.28e-15 | ||||
Fatty acid hydroxylase; This entry includes fatty acid and carotene hydroxylases and sterol desaturases. Beta-carotene hydroxylase is involved in zeaxanthin synthesis by hydroxylating beta-carotene, but the enzyme may be involved in other pathways. This family includes C-5 sterol desaturase and C-4 sterol methyl oxidase. Members of this family are involved in cholesterol biosynthesis and biosynthesis a plant cuticular wax. These enzymes contain two copies of a HXHH motif which coordinate two irons at the catalytic centre. Members of this family are ER integral membrane proteins that share a novel mushroom-shaped fold consisting of four transmembrane (TM1-TM4) helices that anchor them to the membrane capped by a cytosolic domain containing the unique histidine- coordinating di metal centre. Pssm-ID: 397991 Cd Length: 134 Bit Score: 69.00 E-value: 7.28e-15
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ERG3 | COG3000 | Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid ... |
87-226 | 5.49e-05 | ||||
Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]; Pssm-ID: 442238 Cd Length: 158 Bit Score: 42.23 E-value: 5.49e-05
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Blast search parameters | ||||
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