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Conserved domains on  [gi|1063716603|ref|NP_001326231|]
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Fes1B [Arabidopsis thaliana]

Protein Classification

Fes1 domain-containing protein( domain architecture ID 12882)

Fes1 domain-containing protein similar to Hsp70-binding protein 1 (HspBP1) that binds to heat shock protein 70 (Hsp70) which helps to fold other proteins.

Gene Ontology:  GO:0005488

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Fes1 super family cl07287
Nucleotide exchange factor Fes1; Fes1 is a cytosolic homolog of Sls1, an ER protein which has ...
 7-56 3.86e-06

Nucleotide exchange factor Fes1; Fes1 is a cytosolic homolog of Sls1, an ER protein which has nucleotide exchange factor activity. Fes1 in yeast has been shown to bind to the molecular chaperone Hsp70 and has adenyl-nucleotide exchange factor activity.


The actual alignment was detected with superfamily member pfam08609:

Pssm-ID: 462534  Cd Length: 89  Bit Score: 44.54  E-value: 3.86e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1063716603   7 DSISRMKVISQIMKMPEqvleaqgVTPDDLEGMLAELQEHVESIDLANDL 56
Cdd:pfam08609  47 SDAELMKEAMAVLNDPE-------VSLEDKLIALDNLEQLVESIDNANNL 89
 
Name Accession Description Interval E-value
Fes1 pfam08609
Nucleotide exchange factor Fes1; Fes1 is a cytosolic homolog of Sls1, an ER protein which has ...
 7-56 3.86e-06

Nucleotide exchange factor Fes1; Fes1 is a cytosolic homolog of Sls1, an ER protein which has nucleotide exchange factor activity. Fes1 in yeast has been shown to bind to the molecular chaperone Hsp70 and has adenyl-nucleotide exchange factor activity.


Pssm-ID: 462534  Cd Length: 89  Bit Score: 44.54  E-value: 3.86e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1063716603   7 DSISRMKVISQIMKMPEqvleaqgVTPDDLEGMLAELQEHVESIDLANDL 56
Cdd:pfam08609  47 SDAELMKEAMAVLNDPE-------VSLEDKLIALDNLEQLVESIDNANNL 89
 
Name Accession Description Interval E-value
Fes1 pfam08609
Nucleotide exchange factor Fes1; Fes1 is a cytosolic homolog of Sls1, an ER protein which has ...
 7-56 3.86e-06

Nucleotide exchange factor Fes1; Fes1 is a cytosolic homolog of Sls1, an ER protein which has nucleotide exchange factor activity. Fes1 in yeast has been shown to bind to the molecular chaperone Hsp70 and has adenyl-nucleotide exchange factor activity.


Pssm-ID: 462534  Cd Length: 89  Bit Score: 44.54  E-value: 3.86e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1063716603   7 DSISRMKVISQIMKMPEqvleaqgVTPDDLEGMLAELQEHVESIDLANDL 56
Cdd:pfam08609  47 SDAELMKEAMAVLNDPE-------VSLEDKLIALDNLEQLVESIDNANNL 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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