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Conserved domains on  [gi|1063711331|ref|NP_001325429|]
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Ribonuclease III family protein [Arabidopsis thaliana]

Protein Classification

Mini-ribonuclease 3( domain architecture ID 1903763)

Mini-ribonuclease 3 is involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MrnC super family cl43567
23S rRNA maturation mini-RNase III [Translation, ribosomal structure and biogenesis]; 23S rRNA ...
 96-192 2.81e-19

23S rRNA maturation mini-RNase III [Translation, ribosomal structure and biogenesis]; 23S rRNA maturation mini-RNase III is part of the Pathway/BioSystem: 23S rRNA modification


The actual alignment was detected with superfamily member COG1939:

Pssm-ID: 441542  Cd Length: 130  Bit Score: 79.41  E-value: 2.81e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063711331  96 NPASLAFIGDSIYELYARRHFLFPPL-SIEDYNDRVRAVVRCEAQYALLNKLvdDDFLTKEERDILRWGKNLGSARTRTr 174
Cdd:COG1939     9 SPLALAYIGDAVYELYVRTYLLLKGNtKVNDLHKLAVKYVSAKAQAKLLRKL--LPLLTEEELDIVRRGRNAKSGTVPK- 85

                          90       100
                  ....*....|....*....|.
gi 1063711331 175 rragNA---VYNKASSLETLV 192
Cdd:COG1939    86 ----NAdvqTYRYATGFEALI 102
 
Name Accession Description Interval E-value
MrnC COG1939
23S rRNA maturation mini-RNase III [Translation, ribosomal structure and biogenesis]; 23S rRNA ...
 96-192 2.81e-19

23S rRNA maturation mini-RNase III [Translation, ribosomal structure and biogenesis]; 23S rRNA maturation mini-RNase III is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 441542  Cd Length: 130  Bit Score: 79.41  E-value: 2.81e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063711331  96 NPASLAFIGDSIYELYARRHFLFPPL-SIEDYNDRVRAVVRCEAQYALLNKLvdDDFLTKEERDILRWGKNLGSARTRTr 174
Cdd:COG1939     9 SPLALAYIGDAVYELYVRTYLLLKGNtKVNDLHKLAVKYVSAKAQAKLLRKL--LPLLTEEELDIVRRGRNAKSGTVPK- 85

                          90       100
                  ....*....|....*....|.
gi 1063711331 175 rragNA---VYNKASSLETLV 192
Cdd:COG1939    86 ----NAdvqTYRYATGFEALI 102
Ribonuclease_3 pfam00636
Ribonuclease III domain;
100-192 4.03e-17

Ribonuclease III domain;


Pssm-ID: 459883  Cd Length: 101  Bit Score: 73.08  E-value: 4.03e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063711331 100 LAFIGDSIYELYARRHFL--FPPLSIEDYNDRVRAVVRCEAQYALLNKLVDDDFLTKEERDILRWGKNLGSartrTRRRA 177
Cdd:pfam00636   3 LEFLGDAVLELYVREYLFekFPDLREGDLHRLRSALVSNEALAKLARKLGLEKFLTEEELDIRRRNNALGK----GPKRA 78

                          90
                  ....*....|....*
gi 1063711331 178 GNAVYNKASSLETLV 192
Cdd:pfam00636  79 DGKEKVLADAFEALI 93
RIBOc cd00593
RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and ...
 90-165 7.95e-08

RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in post-transcriptional control of mRNA stability and translational efficiency. It is involved in the processing of ribosomal RNA precursors. Prokaryotic RNAse III also plays a role in the maturation of tRNA precursors and in the processing of phage and plasmid transcripts. Eukaryotic RNase III's participate (through direct cleavage) in rRNA processing, in processing of small nucleolar RNAs (snoRNAs) and snRNA's (components of the spliceosome). In eukaryotes RNase III or RNaseIII like enzymes such as Dicer are involved in RNAi (RNA interference) and miRNA (micro-RNA) gene silencing.


Pssm-ID: 238333  Cd Length: 133  Bit Score: 49.15  E-value: 7.95e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063711331  90 KPRSVFNPASLAFIGDSIYELYARRHFL--FPPLSIEDYNDRVRAVVRCEAQYALLNKLVDDDFLTKEERDILRWGKN 165
Cdd:cd00593    14 NEHGRFNNERLEFLGDAVLELVVTEYLFkkFPDLSEGDLTRLRSALVSNETLARLARELGLGKYLRLGKGEEKSGGRL 91
RIBOc smart00535
Ribonuclease III family;
100-152 6.43e-04

Ribonuclease III family;


Pssm-ID: 197778  Cd Length: 129  Bit Score: 38.35  E-value: 6.43e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1063711331  100 LAFIGDSIYELYARRHFL--FPPLSIEDYNDRVRAVVRCEAQYALLNKLVDDDFL 152
Cdd:smart00535  22 LEFLGDAVLELVVTEYLYkkYPDLSEGDLSRLRSALVSNETLARLAKKLGLGEFI 76
 
Name Accession Description Interval E-value
MrnC COG1939
23S rRNA maturation mini-RNase III [Translation, ribosomal structure and biogenesis]; 23S rRNA ...
 96-192 2.81e-19

23S rRNA maturation mini-RNase III [Translation, ribosomal structure and biogenesis]; 23S rRNA maturation mini-RNase III is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 441542  Cd Length: 130  Bit Score: 79.41  E-value: 2.81e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063711331  96 NPASLAFIGDSIYELYARRHFLFPPL-SIEDYNDRVRAVVRCEAQYALLNKLvdDDFLTKEERDILRWGKNLGSARTRTr 174
Cdd:COG1939     9 SPLALAYIGDAVYELYVRTYLLLKGNtKVNDLHKLAVKYVSAKAQAKLLRKL--LPLLTEEELDIVRRGRNAKSGTVPK- 85

                          90       100
                  ....*....|....*....|.
gi 1063711331 175 rragNA---VYNKASSLETLV 192
Cdd:COG1939    86 ----NAdvqTYRYATGFEALI 102
Ribonuclease_3 pfam00636
Ribonuclease III domain;
100-192 4.03e-17

Ribonuclease III domain;


Pssm-ID: 459883  Cd Length: 101  Bit Score: 73.08  E-value: 4.03e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063711331 100 LAFIGDSIYELYARRHFL--FPPLSIEDYNDRVRAVVRCEAQYALLNKLVDDDFLTKEERDILRWGKNLGSartrTRRRA 177
Cdd:pfam00636   3 LEFLGDAVLELYVREYLFekFPDLREGDLHRLRSALVSNEALAKLARKLGLEKFLTEEELDIRRRNNALGK----GPKRA 78

                          90
                  ....*....|....*
gi 1063711331 178 GNAVYNKASSLETLV 192
Cdd:pfam00636  79 DGKEKVLADAFEALI 93
RIBOc cd00593
RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and ...
 90-165 7.95e-08

RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in post-transcriptional control of mRNA stability and translational efficiency. It is involved in the processing of ribosomal RNA precursors. Prokaryotic RNAse III also plays a role in the maturation of tRNA precursors and in the processing of phage and plasmid transcripts. Eukaryotic RNase III's participate (through direct cleavage) in rRNA processing, in processing of small nucleolar RNAs (snoRNAs) and snRNA's (components of the spliceosome). In eukaryotes RNase III or RNaseIII like enzymes such as Dicer are involved in RNAi (RNA interference) and miRNA (micro-RNA) gene silencing.


Pssm-ID: 238333  Cd Length: 133  Bit Score: 49.15  E-value: 7.95e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063711331  90 KPRSVFNPASLAFIGDSIYELYARRHFL--FPPLSIEDYNDRVRAVVRCEAQYALLNKLVDDDFLTKEERDILRWGKN 165
Cdd:cd00593    14 NEHGRFNNERLEFLGDAVLELVVTEYLFkkFPDLSEGDLTRLRSALVSNETLARLARELGLGKYLRLGKGEEKSGGRL 91
RIBOc smart00535
Ribonuclease III family;
100-152 6.43e-04

Ribonuclease III family;


Pssm-ID: 197778  Cd Length: 129  Bit Score: 38.35  E-value: 6.43e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1063711331  100 LAFIGDSIYELYARRHFL--FPPLSIEDYNDRVRAVVRCEAQYALLNKLVDDDFL 152
Cdd:smart00535  22 LEFLGDAVLELVVTEYLYkkYPDLSEGDLSRLRSALVSNETLARLAKKLGLGEFI 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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