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Conserved domains on  [gi|1063721225|ref|NP_001319879|]
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Inositol 1,3,4-trisphosphate 5/6-kinase family protein [Arabidopsis thaliana]

Protein Classification

PLN02941 family protein( domain architecture ID 10010939)

PLN02941 family protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN02941 PLN02941
inositol-tetrakisphosphate 1-kinase
1-256 1.51e-171

inositol-tetrakisphosphate 1-kinase


:

Pssm-ID: 215508 [Multi-domain]  Cd Length: 328  Bit Score: 476.37  E-value: 1.51e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225   1 MYWQQIGKEWRRILEEFRLAHPDVTVLDPPDAILHLRNRQSMLQCVADMNLSDSNGRVGVPKQLVIKKDASSIPEAVNNA 80
Cdd:PLN02941   70 ILHKLYGKEWRQQLEEYREKHPDVTVLDPPDAIQRLHNRQSMLQVVADLKLSDGYGSVGVPKQLVVYDDESSIPDAVALA 149
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225  81 GLRLPLVAKPLVADGSAKSHELSLAYDQHSLLKLEPPLVLQEFVNHGGVLFKVYIVGEAIRVVRRFSLPDVSRRELPKSA 160
Cdd:PLN02941  150 GLKFPLVAKPLVADGSAKSHKMSLAYDQEGLSKLEPPLVLQEFVNHGGVLFKVYVVGDYVKCVRRFSLPDVSEEELSSAE 229
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225 161 GVFRFPRVSCAAASAD---DADLDPSIAELPPRPLLERLAKELRRGLGLRLFNLDIIREHGTRDRFYVIDINYFPGYGKM 237
Cdd:PLN02941  230 GVLPFPRVSNAAASADdadNGGLDPEVAELPPRPFLEDLARELRRRLGLRLFNFDMIREHGTGDRYYVIDINYFPGYAKM 309
                         250
                  ....*....|....*....
gi 1063721225 238 PEYEHVFTDFLLSVVQSQC 256
Cdd:PLN02941  310 PGYETVLTDFLLSLVQKKY 328
 
Name Accession Description Interval E-value
PLN02941 PLN02941
inositol-tetrakisphosphate 1-kinase
1-256 1.51e-171

inositol-tetrakisphosphate 1-kinase


Pssm-ID: 215508 [Multi-domain]  Cd Length: 328  Bit Score: 476.37  E-value: 1.51e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225   1 MYWQQIGKEWRRILEEFRLAHPDVTVLDPPDAILHLRNRQSMLQCVADMNLSDSNGRVGVPKQLVIKKDASSIPEAVNNA 80
Cdd:PLN02941   70 ILHKLYGKEWRQQLEEYREKHPDVTVLDPPDAIQRLHNRQSMLQVVADLKLSDGYGSVGVPKQLVVYDDESSIPDAVALA 149
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225  81 GLRLPLVAKPLVADGSAKSHELSLAYDQHSLLKLEPPLVLQEFVNHGGVLFKVYIVGEAIRVVRRFSLPDVSRRELPKSA 160
Cdd:PLN02941  150 GLKFPLVAKPLVADGSAKSHKMSLAYDQEGLSKLEPPLVLQEFVNHGGVLFKVYVVGDYVKCVRRFSLPDVSEEELSSAE 229
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225 161 GVFRFPRVSCAAASAD---DADLDPSIAELPPRPLLERLAKELRRGLGLRLFNLDIIREHGTRDRFYVIDINYFPGYGKM 237
Cdd:PLN02941  230 GVLPFPRVSNAAASADdadNGGLDPEVAELPPRPFLEDLARELRRRLGLRLFNFDMIREHGTGDRYYVIDINYFPGYAKM 309
                         250
                  ....*....|....*....
gi 1063721225 238 PEYEHVFTDFLLSVVQSQC 256
Cdd:PLN02941  310 PGYETVLTDFLLSLVQKKY 328
Ins134_P3_kin pfam05770
Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain; This family consists of several ...
52-250 4.92e-118

Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain; This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the ATP-grasp domain.


Pssm-ID: 368606  Cd Length: 201  Bit Score: 335.97  E-value: 4.92e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225  52 SDSNGRVGVPKQLVIKKDASSIPEAVNNAGLRLPLVAKPLVADGSAKSHELSLAYDQHSLLKLEPPLVLQEFVNHGGVLF 131
Cdd:pfam05770   1 SMEDGRFGVPPQVVVMKDASSLSRAGAKAGLTFPLIAKPLVADGTAKSHEMSLVYDQEGLNKLQPPLVLQEFVNHGGVLF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225 132 KVYIVGEAIRVVRRFSLPDVSRRELPKSAGVFRFPRVSCAAASADDAD--LDPSIAELPPRPLLERLAKELRRGLGLRLF 209
Cdd:pfam05770  81 KVYVVGEHVTVVKRRSLPDVSAGTLDRSSGSFRFSQVSNLTASADDAEldKILEIAEMPPDPFLEDLARALRRALGLRLF 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063721225 210 NLDIIREHGTRDRFYVIDINYFPGYGKMPEYEHVFTDFLLS 250
Cdd:pfam05770 161 NFDIIRDAGTADRYLVIDINYFPGYAKMPEYETVLTDFFWS 201
LysX COG0189
Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily [Amino acid transport ...
18-234 3.68e-13

Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily [Amino acid transport and metabolism, Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis, Secondary metabolites biosynthesis, transport and catabolism]; Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 439959 [Multi-domain]  Cd Length: 289  Bit Score: 67.66  E-value: 3.68e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225  18 RLAHPDVTVLDPPDAILHLRNRQSMLQcvadmnLSDSNGrVGVPKQLVIKkDASSIPEAVnnAGLRLPLVAKPLVADGS- 96
Cdd:COG0189    76 QLEAAGVPVVNDPEAIRRARDKLFTLQ------LLARAG-IPVPPTLVTR-DPDDLRAFL--EELGGPVVLKPLDGSGGr 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225  97 ----AKSHELSLAYDQHSLLKLEPPLVLQEFVNH-GGVLFKVYIV-GEAIRVVRRFSLPDVSRRELPKSAGVFRFprvsc 170
Cdd:COG0189   146 gvflVEDEDALESILEALTELGSEPVLVQEFIPEeDGRDIRVLVVgGEPVAAIRRIPAEGEFRTNLARGGRAEPV----- 220
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063721225 171 aaasaddadldpsiaELPPRplLERLAKELRRGLGLRLFNLDIIrehGTRDRFYVIDINYFPGY 234
Cdd:COG0189   221 ---------------ELTDE--ERELALRAAPALGLDFAGVDLI---EDDDGPLVLEVNVTPGF 264
 
Name Accession Description Interval E-value
PLN02941 PLN02941
inositol-tetrakisphosphate 1-kinase
1-256 1.51e-171

inositol-tetrakisphosphate 1-kinase


Pssm-ID: 215508 [Multi-domain]  Cd Length: 328  Bit Score: 476.37  E-value: 1.51e-171
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225   1 MYWQQIGKEWRRILEEFRLAHPDVTVLDPPDAILHLRNRQSMLQCVADMNLSDSNGRVGVPKQLVIKKDASSIPEAVNNA 80
Cdd:PLN02941   70 ILHKLYGKEWRQQLEEYREKHPDVTVLDPPDAIQRLHNRQSMLQVVADLKLSDGYGSVGVPKQLVVYDDESSIPDAVALA 149
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225  81 GLRLPLVAKPLVADGSAKSHELSLAYDQHSLLKLEPPLVLQEFVNHGGVLFKVYIVGEAIRVVRRFSLPDVSRRELPKSA 160
Cdd:PLN02941  150 GLKFPLVAKPLVADGSAKSHKMSLAYDQEGLSKLEPPLVLQEFVNHGGVLFKVYVVGDYVKCVRRFSLPDVSEEELSSAE 229
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225 161 GVFRFPRVSCAAASAD---DADLDPSIAELPPRPLLERLAKELRRGLGLRLFNLDIIREHGTRDRFYVIDINYFPGYGKM 237
Cdd:PLN02941  230 GVLPFPRVSNAAASADdadNGGLDPEVAELPPRPFLEDLARELRRRLGLRLFNFDMIREHGTGDRYYVIDINYFPGYAKM 309
                         250
                  ....*....|....*....
gi 1063721225 238 PEYEHVFTDFLLSVVQSQC 256
Cdd:PLN02941  310 PGYETVLTDFLLSLVQKKY 328
Ins134_P3_kin pfam05770
Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain; This family consists of several ...
52-250 4.92e-118

Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain; This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the ATP-grasp domain.


Pssm-ID: 368606  Cd Length: 201  Bit Score: 335.97  E-value: 4.92e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225  52 SDSNGRVGVPKQLVIKKDASSIPEAVNNAGLRLPLVAKPLVADGSAKSHELSLAYDQHSLLKLEPPLVLQEFVNHGGVLF 131
Cdd:pfam05770   1 SMEDGRFGVPPQVVVMKDASSLSRAGAKAGLTFPLIAKPLVADGTAKSHEMSLVYDQEGLNKLQPPLVLQEFVNHGGVLF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225 132 KVYIVGEAIRVVRRFSLPDVSRRELPKSAGVFRFPRVSCAAASADDAD--LDPSIAELPPRPLLERLAKELRRGLGLRLF 209
Cdd:pfam05770  81 KVYVVGEHVTVVKRRSLPDVSAGTLDRSSGSFRFSQVSNLTASADDAEldKILEIAEMPPDPFLEDLARALRRALGLRLF 160
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063721225 210 NLDIIREHGTRDRFYVIDINYFPGYGKMPEYEHVFTDFLLS 250
Cdd:pfam05770 161 NFDIIRDAGTADRYLVIDINYFPGYAKMPEYETVLTDFFWS 201
LysX COG0189
Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily [Amino acid transport ...
18-234 3.68e-13

Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily [Amino acid transport and metabolism, Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis, Secondary metabolites biosynthesis, transport and catabolism]; Glutathione synthase, LysX or RimK-type ligase, ATP-grasp superfamily is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 439959 [Multi-domain]  Cd Length: 289  Bit Score: 67.66  E-value: 3.68e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225  18 RLAHPDVTVLDPPDAILHLRNRQSMLQcvadmnLSDSNGrVGVPKQLVIKkDASSIPEAVnnAGLRLPLVAKPLVADGS- 96
Cdd:COG0189    76 QLEAAGVPVVNDPEAIRRARDKLFTLQ------LLARAG-IPVPPTLVTR-DPDDLRAFL--EELGGPVVLKPLDGSGGr 145
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063721225  97 ----AKSHELSLAYDQHSLLKLEPPLVLQEFVNH-GGVLFKVYIV-GEAIRVVRRFSLPDVSRRELPKSAGVFRFprvsc 170
Cdd:COG0189   146 gvflVEDEDALESILEALTELGSEPVLVQEFIPEeDGRDIRVLVVgGEPVAAIRRIPAEGEFRTNLARGGRAEPV----- 220
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063721225 171 aaasaddadldpsiaELPPRplLERLAKELRRGLGLRLFNLDIIrehGTRDRFYVIDINYFPGY 234
Cdd:COG0189   221 ---------------ELTDE--ERELALRAAPALGLDFAGVDLI---EDDDGPLVLEVNVTPGF 264
Ins134_P3_kin_N pfam17927
Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain; This family consists of several ...
4-33 2.79e-11

Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain; This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase. This entry represents the N-terminal pre-ATP-grasp domain.


Pssm-ID: 407776  Cd Length: 80  Bit Score: 58.26  E-value: 2.79e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 1063721225   4 QQIGKEWRRILEEFRLAHPDVTVLDPPDAI 33
Cdd:pfam17927  51 KLTDKEWRHRLEEFREAHPEVPVLDPPPAI 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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