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HEAT SHOCK PROTEIN 89.1 [Arabidopsis thaliana]
Protein Classification
Hsp90 family chaperone protein ( domain architecture ID 11480452 )
Hsp90 (heat shock protein 90) family chaperone protein, such as molecular chaperone HtpG (high-temperature protein G) that facilitates the folding and conformational changes of a wide array of proteins
List of domain hits
Name
Accession
Description
Interval
E-value
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
94-761
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 729.61
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 94 A E KF E Y QAEV SR L M DL IVN SLYSNKE V FLRELISNASDA L DKLR Y L SV T N PEL SKDAP DL D IRI YA DKE NGII T LT D S GI 173
Cdd:COG0326 3 K E TG E F QAEV KQ L L DL MIH SLYSNKE I FLRELISNASDA I DKLR F L AL T D PEL KEEDG DL K IRI EV DKE AKTL T IS D N GI 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 174 GMTR Q E LVDC LGTIA Q SGT AK F MKA LK D sk D AGG D NN LIGQFGVGFYSAF L VAD R V I V S T K S PKS D KQ - YV WE GEA n SSS 252
Cdd:COG0326 83 GMTR E E VIEN LGTIA K SGT RE F LEK LK G -- D QKK D SD LIGQFGVGFYSAF M VAD K V E V V T R S AGE D AE a VR WE SDG - DGE 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 253 F TI Q E DTDP qsli P RGT R ITLHLK QE A KN F ADPE R IQKLV K N YS Q F VSF PI YTWQ E KGY T K E veveddptetkkddqddq 332
Cdd:COG0326 160 Y TI E E AEKA ---- E RGT E ITLHLK ED A EE F LEEW R LREII K K YS D F IPV PI KMEG E EEE T E E ------------------ 217
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 333 tekkkktkkvverywd W E LT N ETQPI W L R NPK E V T TA EY N EFY RKA F NEYL DPL ASS H FTT EG EV E FRSI LY V P PVS P sg 412
Cdd:COG0326 218 ---------------- D E TI N SATAL W T R SKS E I T DE EY K EFY KHL F HDFE DPL FWI H LNV EG PF E YTGL LY I P KKA P -- 279
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 413 k D D IVNQKT K N - I R LYVKRVFI S DD FD g E L F P R YL S FV K GVVDS H DLPLNVSREILQE S R IVRIMK K RLVR K AF D MILGI 491
Cdd:COG0326 280 - F D LYDRDR K G g I K LYVKRVFI M DD AE - D L L P E YL R FV R GVVDS P DLPLNVSREILQE D R QLKKIR K AITK K VL D ELEKL 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 492 S l SEN RE D YEKFW DN FG KH LK L G CI ED RE N HKR IA P LLRF F S S q S E NDMIS L D EYVE N MK PE QK A IY F I ASD S ITS A KNA 571
Cdd:COG0326 358 A - KND RE K YEKFW KE FG LV LK E G AL ED FK N REK IA D LLRF E S T - K E GGYVT L A EYVE R MK EG QK K IY Y I TGE S REA A EQS 435
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 572 P F LE KMLE KG L EVL Y L VE PIDE VAVQS L KAYKE K D F VDISKE DLDL GDKN E E KE AA - VKK EF GQTCDWI K KR LGDKV AS V 650
Cdd:COG0326 436 P H LE IFKA KG I EVL L L TD PIDE FLISH L EEFDG K K F KSVDSG DLDL DKLE E K KE SE e EEE EF KPLLERF K EA LGDKV KD V 515
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 651 QI S N RL SS SP CV LV SGKFGW S AN ME RLM KA QST gdtisl D YMKGRRVF EINP D H SII K NIN A A ynsn PND E DAMRAID L M 730
Cdd:COG0326 516 RV S A RL TD SP AC LV ADEGDM S RR ME KML KA MGQ ------ D MPEAKPIL EINP N H PLV K KLA A E ---- EDE E LFKDLAE L L 585
650 660 670
....*....|....*....|....*....|.
gi 1063710148 731 YD A AL VSS G FTPDN PA ELGGKIYEMMDV AL S 761
Cdd:COG0326 586 YD Q AL LAE G GLLED PA AFVKRLNKLLEK AL G 616
Name
Accession
Description
Interval
E-value
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
94-761
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 729.61
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 94 A E KF E Y QAEV SR L M DL IVN SLYSNKE V FLRELISNASDA L DKLR Y L SV T N PEL SKDAP DL D IRI YA DKE NGII T LT D S GI 173
Cdd:COG0326 3 K E TG E F QAEV KQ L L DL MIH SLYSNKE I FLRELISNASDA I DKLR F L AL T D PEL KEEDG DL K IRI EV DKE AKTL T IS D N GI 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 174 GMTR Q E LVDC LGTIA Q SGT AK F MKA LK D sk D AGG D NN LIGQFGVGFYSAF L VAD R V I V S T K S PKS D KQ - YV WE GEA n SSS 252
Cdd:COG0326 83 GMTR E E VIEN LGTIA K SGT RE F LEK LK G -- D QKK D SD LIGQFGVGFYSAF M VAD K V E V V T R S AGE D AE a VR WE SDG - DGE 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 253 F TI Q E DTDP qsli P RGT R ITLHLK QE A KN F ADPE R IQKLV K N YS Q F VSF PI YTWQ E KGY T K E veveddptetkkddqddq 332
Cdd:COG0326 160 Y TI E E AEKA ---- E RGT E ITLHLK ED A EE F LEEW R LREII K K YS D F IPV PI KMEG E EEE T E E ------------------ 217
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 333 tekkkktkkvverywd W E LT N ETQPI W L R NPK E V T TA EY N EFY RKA F NEYL DPL ASS H FTT EG EV E FRSI LY V P PVS P sg 412
Cdd:COG0326 218 ---------------- D E TI N SATAL W T R SKS E I T DE EY K EFY KHL F HDFE DPL FWI H LNV EG PF E YTGL LY I P KKA P -- 279
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 413 k D D IVNQKT K N - I R LYVKRVFI S DD FD g E L F P R YL S FV K GVVDS H DLPLNVSREILQE S R IVRIMK K RLVR K AF D MILGI 491
Cdd:COG0326 280 - F D LYDRDR K G g I K LYVKRVFI M DD AE - D L L P E YL R FV R GVVDS P DLPLNVSREILQE D R QLKKIR K AITK K VL D ELEKL 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 492 S l SEN RE D YEKFW DN FG KH LK L G CI ED RE N HKR IA P LLRF F S S q S E NDMIS L D EYVE N MK PE QK A IY F I ASD S ITS A KNA 571
Cdd:COG0326 358 A - KND RE K YEKFW KE FG LV LK E G AL ED FK N REK IA D LLRF E S T - K E GGYVT L A EYVE R MK EG QK K IY Y I TGE S REA A EQS 435
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 572 P F LE KMLE KG L EVL Y L VE PIDE VAVQS L KAYKE K D F VDISKE DLDL GDKN E E KE AA - VKK EF GQTCDWI K KR LGDKV AS V 650
Cdd:COG0326 436 P H LE IFKA KG I EVL L L TD PIDE FLISH L EEFDG K K F KSVDSG DLDL DKLE E K KE SE e EEE EF KPLLERF K EA LGDKV KD V 515
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 651 QI S N RL SS SP CV LV SGKFGW S AN ME RLM KA QST gdtisl D YMKGRRVF EINP D H SII K NIN A A ynsn PND E DAMRAID L M 730
Cdd:COG0326 516 RV S A RL TD SP AC LV ADEGDM S RR ME KML KA MGQ ------ D MPEAKPIL EINP N H PLV K KLA A E ---- EDE E LFKDLAE L L 585
650 660 670
....*....|....*....|....*....|.
gi 1063710148 731 YD A AL VSS G FTPDN PA ELGGKIYEMMDV AL S 761
Cdd:COG0326 586 YD Q AL LAE G GLLED PA AFVKRLNKLLEK AL G 616
PRK05218
PRK05218 heat shock protein 90; Provisional
95-756
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 720.36
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 95 E KF E Y QAEV SR L MD L IVN SLYSNKE V FLRELISNASDA L DKLR YLSV T N P E L SKDAP DL D IRI YA DKE NGII T LT D S GIG 174
Cdd:PRK05218 4 E TG E F QAEV KQ L LH L MIH SLYSNKE I FLRELISNASDA I DKLR FEAL T D P A L YEGDG DL K IRI SF DKE ARTL T IS D N GIG 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 175 MTR Q E LVDC LGTIA Q SGT AK F MKA LK D sk D AGG D NN LIGQFGVGFYSAF L VAD R V I V S T K S PKSDKQ - YV WE GEA n SSSF 253
Cdd:PRK05218 84 MTR E E VIEN LGTIA K SGT KE F LEK LK G -- D QKK D SQ LIGQFGVGFYSAF M VAD K V T V I T R S AGPAAE a VR WE SDG - EGEY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 254 TI Q E DTDP qsli P RGT R ITLHLK QEAKN F A D PE RI QKLV K N YS Q F VSF PI Y twqekgytke V E V E D dptetkkddqddqt 333
Cdd:PRK05218 161 TI E E IEKE ---- E RGT E ITLHLK EDEDE F L D EW RI RSII K K YS D F IPV PI K ---------- L E K E E -------------- 212
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 334 ekkkktkkvverywd W E LT N ETQPI W L R NPK E V T TA EY N EFY RKAFNEYL DPL ASS H FTT EG EV E FRSI LY V P PVS P sgk 413
Cdd:PRK05218 213 --------------- E E TI N SASAL W T R SKS E I T DE EY K EFY KHLAHDFD DPL FWI H NNV EG PF E YTGL LY I P KKA P --- 274
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 414 D D IV N QKT K N - IR LYVKRVFI S DD FD g EL F P R YL S FVKGV V DS H DLPLNVSREILQE S R I V RIMK K RLVR K AF D MILGIS 492
Cdd:PRK05218 275 F D LF N RDR K G g LK LYVKRVFI M DD AE - EL L P E YL R FVKGV I DS E DLPLNVSREILQE D R V V KKIR K AITK K VL D ELEKLA 353
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 493 l SEN RE D YEKFW DN FG KH LK L G CI ED RE N HKRI A P LLRF F S S q S E NDMI SL D EYVE N MK PE QK A IY F I AS DS ITS AKN A P 572
Cdd:PRK05218 354 - KND RE K YEKFW KE FG PV LK E G LY ED FA N REKL A K LLRF A S T - H E GKYV SL A EYVE R MK EG QK K IY Y I TG DS REA AKN S P 431
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 573 F LE KMLE KG L EVL Y L VE PIDE VAVQS L KAYKE K D F VDISKE DLDLG DKN EE KEAA --- VKK EF GQTCDWI K KR LGDKV AS 649
Cdd:PRK05218 432 H LE LFKK KG I EVL L L TD PIDE FWISY L EEFDG K P F KSVARG DLDLG KED EE EKEE kee AEE EF KPLLERL K EA LGDKV KD 511
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 650 V QI S N RL SS SP CV LV SGKFGW S AN ME R L M KA QST gdtisl DYMKGRRVF EINP D H SII K NI naay NSNPNDEDAMRAID L 729
Cdd:PRK05218 512 V RL S H RL TD SP AC LV ADEGDM S TQ ME K L L KA AGQ ------ EVPESKPIL EINP N H PLV K KL ---- ADEADEAKFKDLAE L 581
650 660
....*....|....*....|....*..
gi 1063710148 730 M YD A AL VSS G FTPDN PA ELGGKIY E MM 756
Cdd:PRK05218 582 L YD Q AL LAE G GSLED PA AFVKRLN E LL 608
HSP90
pfam00183 Hsp90 protein;
282-768
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 672.73
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 282 FADPER I QK LVK N YS Q F VS FPIY T W Q EK GYTK EV EV E DDPT E TKKDDQD D QTE K KKKTKKVV E R --------- Y W D WEL T 352
Cdd:pfam00183 2 YLEEKK I KE LVK K YS E F IN FPIY L W V EK EEEV EV PD E EEEE E EEEEEEE D DDP K VEEEDEEE E K kktkkvket V W E WEL L 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 353 N E T Q PIW L RNPKEVT TA EY N EFY RKAFNEYL DPLA SS HF TT EGEVEF R S I L YV P PVS P S gkd D IVN -- Q K TK NI R LYV K R 430
Cdd:pfam00183 82 N K T K PIW T RNPKEVT EE EY A EFY KSLSKDWE DPLA VK HF SV EGEVEF K S L L FI P KRA P F --- D LFE nk K K KN NI K LYV R R 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 431 VFI S DDF D g E L F P R YL S FVKGVVDS H DLPLNVSRE I LQ ESR I VRIM KK R LVRKA F DM IL gi SLS E NR EDY E KFW DN FGK H 510
Cdd:pfam00183 159 VFI T DDF E - D L I P E YL N FVKGVVDS D DLPLNVSRE T LQ QNK I LKVI KK K LVRKA L DM FK -- EIA E EK EDY K KFW KE FGK N 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 511 LKLG C IED RE N HKRI A P LLRF F SS Q S ENDMI SLD E YV EN MK PE QK A IY F I ASD S ITSAK N A PFLE KMLE KG L EVLYL VE P 590
Cdd:pfam00183 236 LKLG I IED SS N RNKL A K LLRF Y SS K S GDELT SLD D YV SR MK EG QK H IY Y I TGE S KEEVE N S PFLE RLKK KG Y EVLYL TD P 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 591 IDE V AVQ S LK AYKE K DF V DIS KE D L D L GDKN EEK EA -- AV KKEF GQTCD W I K KR LGDKV AS V QI SNRL SS SPCVLV SGKF 668
Cdd:pfam00183 316 IDE Y AVQ Q LK EFDG K KL V NVA KE G L E L EEDE EEK KK de EL KKEF EPLTK W L K DV LGDKV EK V VV SNRL VD SPCVLV TSQY 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 669 GWSANMER L MKAQ S - TG D TISLD YM KGRRVF EINP D H S IIK NINAAYNSNPN D ED A MRAID L M Y DA AL VS SGF TPDN PA E 747
Cdd:pfam00183 396 GWSANMER I MKAQ A l RK D SSMSS YM SSKKTL EINP R H P IIK ELLKRVEADKD D KT A KDLAL L L Y ET AL LR SGF SLED PA S 475
490 500
....*....|....*....|.
gi 1063710148 748 LGGK IY E M MDVA L SGKWSSPE 768
Cdd:pfam00183 476 FASR IY R M LKLG L GIDEDEIV 496
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
104-299
1.43e-100
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 308.68
E-value: 1.43e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 104 SR L M DLI VN SLYSNKE V FLRELISNASDALDKLRYLS V T N P E L SK D A P D L D IRI YA DKEN GII T LT D S GIGMT RQ EL VDC 183
Cdd:cd16927 1 NQ L L DLI IH SLYSNKE I FLRELISNASDALDKLRYLS L T D P S L LD D D P E L E IRI SP DKEN RTL T IS D T GIGMT KE EL INN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 184 LGTIA Q SGT AK F MK AL KDSKD agg D NN LIGQFGVGFYSAF L VAD R V I V S TKS PKS D KQ Y V WE GEAN s S S F TI Q E DTDP qs 263
Cdd:cd16927 81 LGTIA R SGT KA F LE AL QEGAK --- D SD LIGQFGVGFYSAF M VAD K V T V T TKS AGD D EG Y R WE SDGG - G S Y TI E E AEGE -- 154
170 180 190
....*....|....*....|....*....|....*.
gi 1063710148 264 l IP RGT R ITLHLK QE AK N F ADPE RI QK LVK N YS Q F V 299
Cdd:cd16927 155 - LG RGT K ITLHLK ED AK E F LEEA RI KE LVK K YS D F I 189
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
117-278
2.11e-06
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 47.26
E-value: 2.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 117 NKEVF LR ELI SN AS D ALD K L rylsvtnpel SKDAPDLDIRIYA D KENGI IT LT D S G I G MTRQE L vdclgtiaqsgtakf M 196
Cdd:smart00387 1 GDPDR LR QVL SN LL D NAI K Y ---------- TPEGGRITVTLER D GDHVE IT VE D N G P G IPPED L --------------- E 55
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 197 K ALKDSKDAGGDNNL IG QF G V G FYSAFLVADRVIV stkspksdkqyvwegeansssf T I QEDTD P qsli PR GT RI T LH L K 276
Cdd:smart00387 56 K IFEPFFRTDKRSRK IG GT G L G LSIVKKLVELHGG ---------------------- E I SVESE P ---- GG GT TF T IT L P 109
..
gi 1063710148 277 Q E 278
Cdd:smart00387 110 L E 111
Name
Accession
Description
Interval
E-value
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
94-761
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 729.61
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 94 A E KF E Y QAEV SR L M DL IVN SLYSNKE V FLRELISNASDA L DKLR Y L SV T N PEL SKDAP DL D IRI YA DKE NGII T LT D S GI 173
Cdd:COG0326 3 K E TG E F QAEV KQ L L DL MIH SLYSNKE I FLRELISNASDA I DKLR F L AL T D PEL KEEDG DL K IRI EV DKE AKTL T IS D N GI 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 174 GMTR Q E LVDC LGTIA Q SGT AK F MKA LK D sk D AGG D NN LIGQFGVGFYSAF L VAD R V I V S T K S PKS D KQ - YV WE GEA n SSS 252
Cdd:COG0326 83 GMTR E E VIEN LGTIA K SGT RE F LEK LK G -- D QKK D SD LIGQFGVGFYSAF M VAD K V E V V T R S AGE D AE a VR WE SDG - DGE 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 253 F TI Q E DTDP qsli P RGT R ITLHLK QE A KN F ADPE R IQKLV K N YS Q F VSF PI YTWQ E KGY T K E veveddptetkkddqddq 332
Cdd:COG0326 160 Y TI E E AEKA ---- E RGT E ITLHLK ED A EE F LEEW R LREII K K YS D F IPV PI KMEG E EEE T E E ------------------ 217
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 333 tekkkktkkvverywd W E LT N ETQPI W L R NPK E V T TA EY N EFY RKA F NEYL DPL ASS H FTT EG EV E FRSI LY V P PVS P sg 412
Cdd:COG0326 218 ---------------- D E TI N SATAL W T R SKS E I T DE EY K EFY KHL F HDFE DPL FWI H LNV EG PF E YTGL LY I P KKA P -- 279
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 413 k D D IVNQKT K N - I R LYVKRVFI S DD FD g E L F P R YL S FV K GVVDS H DLPLNVSREILQE S R IVRIMK K RLVR K AF D MILGI 491
Cdd:COG0326 280 - F D LYDRDR K G g I K LYVKRVFI M DD AE - D L L P E YL R FV R GVVDS P DLPLNVSREILQE D R QLKKIR K AITK K VL D ELEKL 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 492 S l SEN RE D YEKFW DN FG KH LK L G CI ED RE N HKR IA P LLRF F S S q S E NDMIS L D EYVE N MK PE QK A IY F I ASD S ITS A KNA 571
Cdd:COG0326 358 A - KND RE K YEKFW KE FG LV LK E G AL ED FK N REK IA D LLRF E S T - K E GGYVT L A EYVE R MK EG QK K IY Y I TGE S REA A EQS 435
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 572 P F LE KMLE KG L EVL Y L VE PIDE VAVQS L KAYKE K D F VDISKE DLDL GDKN E E KE AA - VKK EF GQTCDWI K KR LGDKV AS V 650
Cdd:COG0326 436 P H LE IFKA KG I EVL L L TD PIDE FLISH L EEFDG K K F KSVDSG DLDL DKLE E K KE SE e EEE EF KPLLERF K EA LGDKV KD V 515
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 651 QI S N RL SS SP CV LV SGKFGW S AN ME RLM KA QST gdtisl D YMKGRRVF EINP D H SII K NIN A A ynsn PND E DAMRAID L M 730
Cdd:COG0326 516 RV S A RL TD SP AC LV ADEGDM S RR ME KML KA MGQ ------ D MPEAKPIL EINP N H PLV K KLA A E ---- EDE E LFKDLAE L L 585
650 660 670
....*....|....*....|....*....|.
gi 1063710148 731 YD A AL VSS G FTPDN PA ELGGKIYEMMDV AL S 761
Cdd:COG0326 586 YD Q AL LAE G GLLED PA AFVKRLNKLLEK AL G 616
PRK05218
PRK05218 heat shock protein 90; Provisional
95-756
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 720.36
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 95 E KF E Y QAEV SR L MD L IVN SLYSNKE V FLRELISNASDA L DKLR YLSV T N P E L SKDAP DL D IRI YA DKE NGII T LT D S GIG 174
Cdd:PRK05218 4 E TG E F QAEV KQ L LH L MIH SLYSNKE I FLRELISNASDA I DKLR FEAL T D P A L YEGDG DL K IRI SF DKE ARTL T IS D N GIG 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 175 MTR Q E LVDC LGTIA Q SGT AK F MKA LK D sk D AGG D NN LIGQFGVGFYSAF L VAD R V I V S T K S PKSDKQ - YV WE GEA n SSSF 253
Cdd:PRK05218 84 MTR E E VIEN LGTIA K SGT KE F LEK LK G -- D QKK D SQ LIGQFGVGFYSAF M VAD K V T V I T R S AGPAAE a VR WE SDG - EGEY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 254 TI Q E DTDP qsli P RGT R ITLHLK QEAKN F A D PE RI QKLV K N YS Q F VSF PI Y twqekgytke V E V E D dptetkkddqddqt 333
Cdd:PRK05218 161 TI E E IEKE ---- E RGT E ITLHLK EDEDE F L D EW RI RSII K K YS D F IPV PI K ---------- L E K E E -------------- 212
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 334 ekkkktkkvverywd W E LT N ETQPI W L R NPK E V T TA EY N EFY RKAFNEYL DPL ASS H FTT EG EV E FRSI LY V P PVS P sgk 413
Cdd:PRK05218 213 --------------- E E TI N SASAL W T R SKS E I T DE EY K EFY KHLAHDFD DPL FWI H NNV EG PF E YTGL LY I P KKA P --- 274
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 414 D D IV N QKT K N - IR LYVKRVFI S DD FD g EL F P R YL S FVKGV V DS H DLPLNVSREILQE S R I V RIMK K RLVR K AF D MILGIS 492
Cdd:PRK05218 275 F D LF N RDR K G g LK LYVKRVFI M DD AE - EL L P E YL R FVKGV I DS E DLPLNVSREILQE D R V V KKIR K AITK K VL D ELEKLA 353
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 493 l SEN RE D YEKFW DN FG KH LK L G CI ED RE N HKRI A P LLRF F S S q S E NDMI SL D EYVE N MK PE QK A IY F I AS DS ITS AKN A P 572
Cdd:PRK05218 354 - KND RE K YEKFW KE FG PV LK E G LY ED FA N REKL A K LLRF A S T - H E GKYV SL A EYVE R MK EG QK K IY Y I TG DS REA AKN S P 431
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 573 F LE KMLE KG L EVL Y L VE PIDE VAVQS L KAYKE K D F VDISKE DLDLG DKN EE KEAA --- VKK EF GQTCDWI K KR LGDKV AS 649
Cdd:PRK05218 432 H LE LFKK KG I EVL L L TD PIDE FWISY L EEFDG K P F KSVARG DLDLG KED EE EKEE kee AEE EF KPLLERL K EA LGDKV KD 511
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 650 V QI S N RL SS SP CV LV SGKFGW S AN ME R L M KA QST gdtisl DYMKGRRVF EINP D H SII K NI naay NSNPNDEDAMRAID L 729
Cdd:PRK05218 512 V RL S H RL TD SP AC LV ADEGDM S TQ ME K L L KA AGQ ------ EVPESKPIL EINP N H PLV K KL ---- ADEADEAKFKDLAE L 581
650 660
....*....|....*....|....*..
gi 1063710148 730 M YD A AL VSS G FTPDN PA ELGGKIY E MM 756
Cdd:PRK05218 582 L YD Q AL LAE G GSLED PA AFVKRLN E LL 608
HSP90
pfam00183 Hsp90 protein;
282-768
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 672.73
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 282 FADPER I QK LVK N YS Q F VS FPIY T W Q EK GYTK EV EV E DDPT E TKKDDQD D QTE K KKKTKKVV E R --------- Y W D WEL T 352
Cdd:pfam00183 2 YLEEKK I KE LVK K YS E F IN FPIY L W V EK EEEV EV PD E EEEE E EEEEEEE D DDP K VEEEDEEE E K kktkkvket V W E WEL L 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 353 N E T Q PIW L RNPKEVT TA EY N EFY RKAFNEYL DPLA SS HF TT EGEVEF R S I L YV P PVS P S gkd D IVN -- Q K TK NI R LYV K R 430
Cdd:pfam00183 82 N K T K PIW T RNPKEVT EE EY A EFY KSLSKDWE DPLA VK HF SV EGEVEF K S L L FI P KRA P F --- D LFE nk K K KN NI K LYV R R 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 431 VFI S DDF D g E L F P R YL S FVKGVVDS H DLPLNVSRE I LQ ESR I VRIM KK R LVRKA F DM IL gi SLS E NR EDY E KFW DN FGK H 510
Cdd:pfam00183 159 VFI T DDF E - D L I P E YL N FVKGVVDS D DLPLNVSRE T LQ QNK I LKVI KK K LVRKA L DM FK -- EIA E EK EDY K KFW KE FGK N 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 511 LKLG C IED RE N HKRI A P LLRF F SS Q S ENDMI SLD E YV EN MK PE QK A IY F I ASD S ITSAK N A PFLE KMLE KG L EVLYL VE P 590
Cdd:pfam00183 236 LKLG I IED SS N RNKL A K LLRF Y SS K S GDELT SLD D YV SR MK EG QK H IY Y I TGE S KEEVE N S PFLE RLKK KG Y EVLYL TD P 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 591 IDE V AVQ S LK AYKE K DF V DIS KE D L D L GDKN EEK EA -- AV KKEF GQTCD W I K KR LGDKV AS V QI SNRL SS SPCVLV SGKF 668
Cdd:pfam00183 316 IDE Y AVQ Q LK EFDG K KL V NVA KE G L E L EEDE EEK KK de EL KKEF EPLTK W L K DV LGDKV EK V VV SNRL VD SPCVLV TSQY 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 669 GWSANMER L MKAQ S - TG D TISLD YM KGRRVF EINP D H S IIK NINAAYNSNPN D ED A MRAID L M Y DA AL VS SGF TPDN PA E 747
Cdd:pfam00183 396 GWSANMER I MKAQ A l RK D SSMSS YM SSKKTL EINP R H P IIK ELLKRVEADKD D KT A KDLAL L L Y ET AL LR SGF SLED PA S 475
490 500
....*....|....*....|.
gi 1063710148 748 LGGK IY E M MDVA L SGKWSSPE 768
Cdd:pfam00183 476 FASR IY R M LKLG L GIDEDEIV 496
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
95-761
0e+00
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 635.18
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 95 E K F EY QAE VSR LM D LI V N SL YSNKE V FLRELISNASDA L DK L RY L S V T N P ELSKDA P D L D IR IYA DKEN GII T LT D S GIG 174
Cdd:PTZ00272 3 E T F AF QAE INQ LM S LI I N TF YSNKE I FLRELISNASDA C DK I RY Q S L T D P SVLGES P R L C IR VVP DKEN KTL T VE D N GIG 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 175 MT RQE LV DC LGTIA Q SGT AK FM K AL kdsk D AGGD NNL IGQFGVGFYSA F LVADRV I V ST K S p K SD KQ YVWE GE A n SSS FT 254
Cdd:PTZ00272 83 MT KAD LV NN LGTIA R SGT KA FM E AL ---- E AGGD MSM IGQFGVGFYSA Y LVADRV T V TS K N - N SD ES YVWE SS A - GGT FT 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 255 I Q ed TD P Q S LIP RGTRITLHLK QEAKNFAD P E R IQK L V K NY S Q F VSFP I YTWQ EK GYT KEV EV ED DPTET K K D D ------ 328
Cdd:PTZ00272 157 I T -- ST P E S DMK RGTRITLHLK EDQMEYLE P R R LKE L I K KH S E F IGYD I ELMV EK TTE KEV TD ED EEDTK K A D E dgeepk 234
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 329 ---- QDDQTE KKKKTKKV V E RYWDW E LT N ETQ P I W L R N PK E VT TA EY NE FY RKAF N EYL DP L A SS HF TT EG EV EFRSI LY 404
Cdd:PTZ00272 235 veev KEGDEG KKKKTKKV K E VTKEY E VQ N KHK P L W T R D PK D VT KE EY AA FY KAIS N DWE DP A A TK HF SV EG QL EFRSI MF 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 405 VP PVS P S gkd D IV -- N Q K TK NI R LYV K RVFI S D DFD g E L F P RY L S FVKGVVDS H DLPLN V SRE I LQ ESR I VRIMK K RL V R 482
Cdd:PTZ00272 315 VP KRA P F --- D MF ep N K K RN NI K LYV R RVFI M D NCE - D L C P DW L G FVKGVVDS E DLPLN I SRE N LQ QNK I LKVIR K NI V K 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 483 K AFD M IL gi SLS EN R EDY EK F WDN FGK HL KLG CI ED RE N H K RIAP LLRF F S SQ S END M IS L DE YV EN MK PE QK A IY F I AS 562
Cdd:PTZ00272 391 K CLE M FD -- EVA EN K EDY KQ F YEQ FGK NI KLG IH ED TA N R K KLME LLRF Y S TE S GEE M TT L KD YV TR MK AG QK S IY Y I TG 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 563 DS ITSAKNA PF L E KMLEK GLEVL YLV EPIDE VAV Q SL K AYKE K D F VDIS KE DLDLGDKN EEK EA -- AV K KEFGQT C DWI K 640
Cdd:PTZ00272 469 DS KKKLETS PF I E QARRR GLEVL FMT EPIDE YVM Q QV K DFED K K F ACLT KE GVHFEESE EEK QQ re EE K AACEKL C KTM K 548
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 641 KR LGDKV AS V QI S N RLS S SPC V LV SGK FGWSA N ME RL M KA Q STG D TISLD YM KGRRVF E I NP D H S IIK NINAAYNSNP ND 720
Cdd:PTZ00272 549 EV LGDKV EK V IV S E RLS T SPC I LV TSE FGWSA H ME QI M RN Q ALR D SSMAQ YM MSKKTM E L NP R H P IIK ELRRRVGADE ND 628
650 660 670 680
....*....|....*....|....*....|....*....|.
gi 1063710148 721 EDAMRAID L MY D AA L VS SGF TPDN P AELGGK I YE M MDVA LS 761
Cdd:PTZ00272 629 KAVKDLVF L LF D TS L LT SGF QLED P TGYAER I NR M IKLG LS 669
PTZ00130
PTZ00130 heat shock protein 90; Provisional
95-760
2.00e-177
heat shock protein 90; Provisional
Pssm-ID: 185466 [Multi-domain]
Cd Length: 814
Bit Score: 530.38
E-value: 2.00e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 95 E KFE YQ A EV S RLMD L IVNSLY SN KEVFLRELISNA S DAL D K L R Y LS VTNPELSKDAPD L D IRI Y A D KE NG I ITL TD S GIG 174
Cdd:PTZ00130 66 E QHQ YQ T EV T RLMD I IVNSLY TQ KEVFLRELISNA A DAL E K I R F LS LSDESVLGEEKK L E IRI S A N KE KN I LSI TD T GIG 145
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 175 MT RQE L VDC LGTIA Q SGT AK F MK A LKD S kda GGD NN LIGQFGVGFYSAFLVAD R VIV S TK S p KS D K QY V WE GE A N s SS FT 254
Cdd:PTZ00130 146 MT KED L INN LGTIA K SGT SN F LE A ISK S --- GGD MS LIGQFGVGFYSAFLVAD K VIV Y TK N - NN D E QY I WE ST A D - AK FT 220
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 255 I QE D TDPQS L i P RGTRI T LHLK QE A K N FADPERIQK L VKN YSQF VSF PIY TWQ E KG YT K EV ------ E V E D DP T -- ET K K 326
Cdd:PTZ00130 221 I YK D PRGST L - K RGTRI S LHLK ED A T N LMNDKKLVD L ISK YSQF IQY PIY LLH E NV YT E EV ladiak E M E N DP N yd SV K V 299
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 327 DDQ DD QTE K KKKTK K V V ER ywd W E L T NE TQ PIWLR N PKE V T TAE Y NE F YR -- KA FN E yl D PL ASS HF TT EGE V EF RSIL Y 404
Cdd:PTZ00130 300 EET DD PNK K TRTVE K K V KK --- W K L M NE QK PIWLR P PKE L T DED Y KK F FS vl SG FN D -- E PL YHI HF FA EGE I EF KCLI Y 374
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 405 V P PVS PS GK D DIVN q K TKN I R LYV K RV FIS D D F d G E LF PRY L SFVKGVVDS H DLPLNVSRE I LQ ESR I VRIMK KR L VRK A 484
Cdd:PTZ00130 375 I P SRA PS IN D HLFT - K QNS I K LYV R RV LVA D E F - V E FL PRY M SFVKGVVDS D DLPLNVSRE Q LQ QNK I LKAVS KR I VRK I 452
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 485 F D MI -- L GISLSE N R E D -------------------------- Y EKFWDNFG K H LK L GC I ED RE N HKR I AP LL R F FSSQS 536
Cdd:PTZ00130 453 L D TF rt L YKEGKK N K E T lraelaketdeekkkeiqkkinepst Y KLIYKEYR K Y LK T GC Y ED DI N RNK I VK LL L F KTMLH 532
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 537 END m ISLD E Y V ENMKP E QK A IY FIAS DS ITSAKNA P F L EKMLE K GLE V LY L V E PI DE VA VQ SLKA Y KE K D F VD I S K EDL - 615
Cdd:PTZ00130 533 PKS - ISLD T Y I ENMKP D QK F IY YASG DS YEYLSKI P Q L QIFKK K NID V VF L T E SV DE SC VQ RVQE Y DG K K F KS I Q K GEI t 611
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 616 - D L GDKNEE KE AA VKK EFGQTC D W I KKR L GDKVAS V Q IS N RL SSS PC VL VS GKF G W S AN ME R LMK AQ - STG D T I SL dy M K 693
Cdd:PTZ00130 612 f E L TEDEKK KE EK VKK MYKALI D V I SDT L RNQIFK V E IS R RL VDA PC AV VS TEW G L S GQ ME K LMK IN v NNS D Q I KA -- M S 689
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1063710148 694 G RRVF EINPDH S I IKNINAAYN SNP N D EDAMRA I DLM Y DA A LVS SGF TPDNP A E L GGKI Y EMMDVA L 760
Cdd:PTZ00130 690 G QKIL EINPDH P I MIDLLKRSV SNP K D SQLTES I KII Y QS A KLA SGF DLEDT A D L AQIV Y DHINQK L 756
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
104-299
1.43e-100
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 308.68
E-value: 1.43e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 104 SR L M DLI VN SLYSNKE V FLRELISNASDALDKLRYLS V T N P E L SK D A P D L D IRI YA DKEN GII T LT D S GIGMT RQ EL VDC 183
Cdd:cd16927 1 NQ L L DLI IH SLYSNKE I FLRELISNASDALDKLRYLS L T D P S L LD D D P E L E IRI SP DKEN RTL T IS D T GIGMT KE EL INN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 184 LGTIA Q SGT AK F MK AL KDSKD agg D NN LIGQFGVGFYSAF L VAD R V I V S TKS PKS D KQ Y V WE GEAN s S S F TI Q E DTDP qs 263
Cdd:cd16927 81 LGTIA R SGT KA F LE AL QEGAK --- D SD LIGQFGVGFYSAF M VAD K V T V T TKS AGD D EG Y R WE SDGG - G S Y TI E E AEGE -- 154
170 180 190
....*....|....*....|....*....|....*.
gi 1063710148 264 l IP RGT R ITLHLK QE AK N F ADPE RI QK LVK N YS Q F V 299
Cdd:cd16927 155 - LG RGT K ITLHLK ED AK E F LEEA RI KE LVK K YS D F I 189
PRK14083
PRK14083 HSP90 family protein; Provisional
99-469
1.16e-37
HSP90 family protein; Provisional
Pssm-ID: 237603 [Multi-domain]
Cd Length: 601
Bit Score: 149.32
E-value: 1.16e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 99 Y Q AEVSRLM DL IVNS LYS NKE V FL REL IS NA S DA LDKL R Y L SV T N P EL skdapdld IRI Y - A D KEN G IITLT D S GIG M T R 177
Cdd:PRK14083 5 F Q VDLRGVI DL LSRH LYS SPR V YV REL LQ NA V DA ITAR R A L DP T A P GR -------- IRI E l T D AGG G TLIVE D N GIG L T E 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 178 Q E LVDC L G TI AQ S gtakfmkalkd SK -- DAG G D -- N NLI GQFG V G FY S A FLVAD RVI V STK S P K SDKQYV W E G E A N s SSF 253
Cdd:PRK14083 77 E E VHEF L A TI GR S ----------- SK rd ENL G F ar N DFL GQFG I G LL S C FLVAD EIV V VSR S A K DGPAVE W R G K A D - GTY 144
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 254 TIQE dt DPQSLIPR GT RIT L HLKQE A KNFADP E RIQK L V K N Y SQFVSF PI Y twqekgytkeve VE DDP tetkkddqddqt 333
Cdd:PRK14083 145 SVRK -- LETERAEP GT TVY L RPRPD A EEWLER E TVEE L A K K Y GSLLPV PI R ------------ VE GEK ------------ 198
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 334 ekkkktkkvverywdw ELT NET Q P I W L R NP -- K E VTTAEYNEFYRKAF - NEY LD -- PL ASSHFTT EG evefrs IL YV P P V 408
Cdd:PRK14083 199 ---------------- GGV NET P P P W T R DY pd P E TRREALLAYGEELL g FTP LD vi PL DVPSGGL EG ------ VA YV L P Y 256
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063710148 409 SP S gkddi VNQKT K N i R L Y V KR VFI S DDFDG e L F P RYLS FV KG VV DSHD L PLNV SRE I L Q E 469
Cdd:PRK14083 257 AV S ----- PAARR K H - R V Y L KR MLL S EEAEN - L L P DWAF FV RC VV NTDE L RPTA SRE A L Y E 310
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
117-278
2.11e-06
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 47.26
E-value: 2.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 117 NKEVF LR ELI SN AS D ALD K L rylsvtnpel SKDAPDLDIRIYA D KENGI IT LT D S G I G MTRQE L vdclgtiaqsgtakf M 196
Cdd:smart00387 1 GDPDR LR QVL SN LL D NAI K Y ---------- TPEGGRITVTLER D GDHVE IT VE D N G P G IPPED L --------------- E 55
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 197 K ALKDSKDAGGDNNL IG QF G V G FYSAFLVADRVIV stkspksdkqyvwegeansssf T I QEDTD P qsli PR GT RI T LH L K 276
Cdd:smart00387 56 K IFEPFFRTDKRSRK IG GT G L G LSIVKKLVELHGG ---------------------- E I SVESE P ---- GG GT TF T IT L P 109
..
gi 1063710148 277 Q E 278
Cdd:smart00387 110 L E 111
HATPase_MORC-like
cd16931 Histidine kinase-like ATPase domain of human microrchidia (MORC) family CW-type zinc finger ...
122-238
2.44e-05
Histidine kinase-like ATPase domain of human microrchidia (MORC) family CW-type zinc finger proteins MORC1-4, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domain of human microrchidia (MORC) family CW-type zinc finger proteins MORC1-4, and related domains. In addition to the HATPase domain, MORC family proteins have a CW-type zinc finger domain containing four conserved cysteines and two conserved tryptophans, and coiled-coil domains at the carboxy-terminus. MORC1 has cross-species differential methylation in association with early life stress, and genome-wide association with major depressive disorder (MDD). MORC2 is involved in several nuclear processes, including transcription modulation and DNA damage repair, and exhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY. MORC3 regulates p53, and is an antiviral factor which plays an important role during HSV-1 and HCMV infection, and is a positive regulator of influenza virus transcription. MORC4 is highly expressed in a subset of diffuse large B-cell lymphomas and has potential as a lymphoma biomarker.
Pssm-ID: 340408 [Multi-domain]
Cd Length: 118
Bit Score: 44.32
E-value: 2.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 122 LR EL IS NA S DA ldklrylsvtnpelsk DA PD LDI R I -- YADKEN G I - ITLT D S G I GMT RQ E LVDCLG tiaqsgtak F MKA 198
Cdd:cd16931 16 VA EL VD NA R DA ---------------- DA TR LDI F I dd INLLRG G F m LSFL D D G N GMT PE E AHHMIS --------- F GFS 70
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1063710148 199 L K D S K dagg D NNL IG QF G V GF Y S - AFLVADR VIV S TK SPK S 238
Cdd:cd16931 71 D K R S D ---- D HDH IG RY G N GF K S g SMRLGRD VIV F TK KDE S 107
HATPase_c_3
pfam13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ...
147-269
4.86e-04
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain]
Cd Length: 135
Bit Score: 40.78
E-value: 4.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 147 S K DA PDLD I R I YAD K EN G I --- I TLT D S G I GM TRQ EL VD clgtiaqsgtak FMKALKDS K D A GGDNNLI G QF G V G FYS A F 223
Cdd:pfam13589 12 S I DA DATN I K I EVN K NR G G gte I VIE D D G H GM SPE EL IN ------------ ALRLATSA K E A KRGSTDL G RY G I G LKL A S 79
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1063710148 224 L VADR - VI V ST K sp K SD K QYV --------- W E GEANSSSF T IQEDTDPQS L IPR -- GT 269
Cdd:pfam13589 80 L SLGA k LT V TS K -- K EG K SST ltldrdkis N E NDWLLPLL T PAPIENFDE L DKD ah GT 135
HATPase_c
pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ...
117-278
3.60e-03
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain]
Cd Length: 109
Bit Score: 37.73
E-value: 3.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 117 NK E VF LR ELI SN AS D ALD K L rylsvtnpel SKD A PDLDIRIYAD k ENGII T LT D S GIG MTR q E LVDCLGT iaqsgta K F M 196
Cdd:pfam02518 1 GD E LR LR QVL SN LL D NAL K H ---------- AAK A GEITVTLSEG - GELTL T VE D N GIG IPP - E DLPRIFE ------- P F S 61
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 197 K A L K DS kdaggdnnl I G QF G V G FYSAFLVADR vivstkspksdkqyv WE G eansssf TI QEDTD P qsli PR GT RI TL H L K 276
Cdd:pfam02518 62 T A D K RG --------- G G GT G L G LSIVRKLVEL --------------- LG G ------- TI TVESE P ---- GG GT TV TL T L P 106
..
gi 1063710148 277 QE 278
Cdd:pfam02518 107 LA 108
HATPase_TopVIB-like
cd16933 Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family ...
123-276
5.92e-03
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family includes the histidine kinase-like ATPase (HATPase) domain of the B subunit of topoisomerase VI (Topo VIB). Topo VI is a heterotetrameric complex composed of two TopVIA and two TopVIB subunits and is categorized as a type II B DNA topoisomerase. It is found in archaea and also in plants. Type II enzymes cleave both strands of a DNA duplex and pass a second duplex through the resulting break in an ATP-dependent mechanism. DNA cleavage by Topo VI generates two-nucleotide 5'-protruding ends.
Pssm-ID: 340410 [Multi-domain]
Cd Length: 203
Bit Score: 38.87
E-value: 5.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 123 REL IS N AS DA LDKLRY L svtnpelskda PD LDIR I - YAD K ENGIITLT D S G I G MTRQELVDCL G TIAQS gt A K F mk AL K D 201
Cdd:cd16933 25 REL VE N SL DA TEEAGI L ----------- PD IKVE I e EIG K DHYKVIVE D N G P G IPEEQIPKVF G KVLYG -- S K Y -- HN K Q 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063710148 202 S K daggdnnli GQ F G V G FYS A F L VAD ------- RV I V STK SPKSDKQYVWEGEANSSSFT I Q E DTD - PQSLIPR GTR IT L 273
Cdd:cd16933 90 S R --------- GQ Q G L G ISA A V L YSQ mttgkpv EI I S STK DSNYAYVVKLMIDTDKNEPE I L E KEE v ENRYKWH GTR VE L 160
...
gi 1063710148 274 H L K 276
Cdd:cd16933 161 E L E 163
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
