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Conserved domains on  [gi|1063678456|ref|NP_001319063|]
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Vacuolar sorting protein 39 [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Vps39_2 pfam10367
Vacuolar sorting protein 39 domain 2; This domain is found on the vacuolar sorting protein ...
 850-958 3.43e-35

Vacuolar sorting protein 39 domain 2; This domain is found on the vacuolar sorting protein Vps39 which is a component of the C-Vps complex. Vps39 is thought to be required for the fusion of endosomes and other types of transport intermediates with the vacuole. In Saccharomyces cerevisiae, Vps39 has been shown to stimulate nucleotide exchange. This domain is involved in localization and in mediating the interactions of Vps39 with Vps11.


:

Pssm-ID: 402126  Cd Length: 109  Bit Score: 129.30  E-value: 3.43e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678456 850 VRLLHNHGESLDPLQVLDKLSPDMPLKLASDTILRMLRARVHHHRQGQIVHNISRALDVDSRLARLEERSRHMQINDESL 929
Cdd:pfam10367   1 LDLLNKHAERIDPAQVLQLLPDEIPLQDLSSFLERALRNSSEAKREAQVVKNLSKAENLQVEEELLKLRSRKVRVTEESV 80

                          90       100
                  ....*....|....*....|....*....
gi 1063678456 930 CDSCYARLGTKLFAMYPDDTIVCYKCYRR 958
Cdd:pfam10367  81 CAVCHKRLGESVFVVYPNGVVVHYGCFRR 109
Clathrin pfam00637
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ...
 753-837 7.13e-07

Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.


:

Pssm-ID: 459884 [Multi-domain]  Cd Length: 142  Bit Score: 49.56  E-value: 7.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678456 753 EVDVRERLQAFLQSSDLYDPEEILELVEGSELWLEKAILYRRIGKETLVLQILaLKLEDCAAAEQYCVEIGRPDAFMQLL 832
Cdd:pfam00637  54 KYDDPEELEEFLKKNNNYDLEKVAKLCEKADLYEEAVILYKKIGNWKEAISLL-KKLGDYKDAIEYAVKSSNPELWEELL 132


                  ....*
gi 1063678456 833 DMYLD 837
Cdd:pfam00637 133 EALLD 137
 
Name Accession Description Interval E-value
Vps39_2 pfam10367
Vacuolar sorting protein 39 domain 2; This domain is found on the vacuolar sorting protein ...
 850-958 3.43e-35

Vacuolar sorting protein 39 domain 2; This domain is found on the vacuolar sorting protein Vps39 which is a component of the C-Vps complex. Vps39 is thought to be required for the fusion of endosomes and other types of transport intermediates with the vacuole. In Saccharomyces cerevisiae, Vps39 has been shown to stimulate nucleotide exchange. This domain is involved in localization and in mediating the interactions of Vps39 with Vps11.


Pssm-ID: 402126  Cd Length: 109  Bit Score: 129.30  E-value: 3.43e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678456 850 VRLLHNHGESLDPLQVLDKLSPDMPLKLASDTILRMLRARVHHHRQGQIVHNISRALDVDSRLARLEERSRHMQINDESL 929
Cdd:pfam10367   1 LDLLNKHAERIDPAQVLQLLPDEIPLQDLSSFLERALRNSSEAKREAQVVKNLSKAENLQVEEELLKLRSRKVRVTEESV 80

                          90       100
                  ....*....|....*....|....*....
gi 1063678456 930 CDSCYARLGTKLFAMYPDDTIVCYKCYRR 958
Cdd:pfam10367  81 CAVCHKRLGESVFVVYPNGVVVHYGCFRR 109
Clathrin pfam00637
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ...
 753-837 7.13e-07

Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.


Pssm-ID: 459884 [Multi-domain]  Cd Length: 142  Bit Score: 49.56  E-value: 7.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678456 753 EVDVRERLQAFLQSSDLYDPEEILELVEGSELWLEKAILYRRIGKETLVLQILaLKLEDCAAAEQYCVEIGRPDAFMQLL 832
Cdd:pfam00637  54 KYDDPEELEEFLKKNNNYDLEKVAKLCEKADLYEEAVILYKKIGNWKEAISLL-KKLGDYKDAIEYAVKSSNPELWEELL 132


                  ....*
gi 1063678456 833 DMYLD 837
Cdd:pfam00637 133 EALLD 137
CLH smart00299
Clathrin heavy chain repeat homology;
755-837 3.07e-04

Clathrin heavy chain repeat homology;


Pssm-ID: 128594 [Multi-domain]  Cd Length: 140  Bit Score: 41.88  E-value: 3.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678456  755 DVRERLQAFlqsSDLYDPEEILELVEGSELWLEKAILYRRIGKETLVLQILALKLEDCAAAEQYCVEIGRPDAFMQLLDM 834
Cdd:smart00299  58 KEIERLDNK---SNHYDIEKVGKLCEKAKLYEEAVELYKKDGNFKDAIVTLIEHLGNYEKAIEYFVKQNNPELWAEVLKA 134


                   ...
gi 1063678456  835 YLD 837
Cdd:smart00299 135 LLD 137
 
Name Accession Description Interval E-value
Vps39_2 pfam10367
Vacuolar sorting protein 39 domain 2; This domain is found on the vacuolar sorting protein ...
 850-958 3.43e-35

Vacuolar sorting protein 39 domain 2; This domain is found on the vacuolar sorting protein Vps39 which is a component of the C-Vps complex. Vps39 is thought to be required for the fusion of endosomes and other types of transport intermediates with the vacuole. In Saccharomyces cerevisiae, Vps39 has been shown to stimulate nucleotide exchange. This domain is involved in localization and in mediating the interactions of Vps39 with Vps11.


Pssm-ID: 402126  Cd Length: 109  Bit Score: 129.30  E-value: 3.43e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678456 850 VRLLHNHGESLDPLQVLDKLSPDMPLKLASDTILRMLRARVHHHRQGQIVHNISRALDVDSRLARLEERSRHMQINDESL 929
Cdd:pfam10367   1 LDLLNKHAERIDPAQVLQLLPDEIPLQDLSSFLERALRNSSEAKREAQVVKNLSKAENLQVEEELLKLRSRKVRVTEESV 80

                          90       100
                  ....*....|....*....|....*....
gi 1063678456 930 CDSCYARLGTKLFAMYPDDTIVCYKCYRR 958
Cdd:pfam10367  81 CAVCHKRLGESVFVVYPNGVVVHYGCFRR 109
Clathrin pfam00637
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ...
 753-837 7.13e-07

Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.


Pssm-ID: 459884 [Multi-domain]  Cd Length: 142  Bit Score: 49.56  E-value: 7.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678456 753 EVDVRERLQAFLQSSDLYDPEEILELVEGSELWLEKAILYRRIGKETLVLQILaLKLEDCAAAEQYCVEIGRPDAFMQLL 832
Cdd:pfam00637  54 KYDDPEELEEFLKKNNNYDLEKVAKLCEKADLYEEAVILYKKIGNWKEAISLL-KKLGDYKDAIEYAVKSSNPELWEELL 132


                  ....*
gi 1063678456 833 DMYLD 837
Cdd:pfam00637 133 EALLD 137
CLH smart00299
Clathrin heavy chain repeat homology;
755-837 3.07e-04

Clathrin heavy chain repeat homology;


Pssm-ID: 128594 [Multi-domain]  Cd Length: 140  Bit Score: 41.88  E-value: 3.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063678456  755 DVRERLQAFlqsSDLYDPEEILELVEGSELWLEKAILYRRIGKETLVLQILALKLEDCAAAEQYCVEIGRPDAFMQLLDM 834
Cdd:smart00299  58 KEIERLDNK---SNHYDIEKVGKLCEKAKLYEEAVELYKKDGNFKDAIVTLIEHLGNYEKAIEYFVKQNNPELWAEVLKA 134


                   ...
gi 1063678456  835 YLD 837
Cdd:smart00299 135 LLD 137
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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