|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
1-510 |
0e+00 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 1088.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 1 MSNIDIEGILKELPNDG-RIPKTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILA 79
Cdd:PLN02461 1 MANIDIEGILKGLPADGlRRPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 80 AVMLDTKGPEIRTGFLKDGNPIQLKEGQEITITTDYDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPES 159
Cdd:PLN02461 81 AVMLDTKGPEIRTGFLKDGKPVQLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLSCDVEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 160 GTVRCRCENSAMLGERKNVNLPGVVVDLPTLTDKDIEDILGWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIMLMS 239
Cdd:PLN02461 161 GTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDILQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLIS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 240 KVENQEGVINFDEILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 319
Cdd:PLN02461 241 KVENQEGLDNFDDILAESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 320 NAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKEMIRATPLPMSPLESLASSAVRTANKARAKLII 399
Cdd:PLN02461 321 NAVLDGTDCVMLSGETAAGAYPELAVKTMARICREAEASLDYGALFKEIMRSAPLPMSPLESLASSAVRTANKVKASLIV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 400 VLTRGGSTANLVAKYRPAVPILSVVVPVMTTDSFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDSEATEVIIEAALKS 479
Cdd:PLN02461 401 VLTRGGTTARLVAKYRPAVPILSVVVPEITTDSFDWSCSDEAPARHSLIYRGLIPVLAEGSAKATDSESTEEILEAAIEH 480
|
490 500 510
....*....|....*....|....*....|.
gi 1063730757 480 ATQRGLCNRGDAIVALHRIGAASVIKICVVK 510
Cdd:PLN02461 481 AKKKGLCKPGDSVVALHRIGGASVIKILTVK 511
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
19-509 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 714.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 19 IPKTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDG 98
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 99 NPIQLKEGQEITITTDY-DIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESgTVRCRCENSAMLGERKN 177
Cdd:cd00288 81 KDISLKAGDKFLVTTDPaAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDK-TLVCEVLNGGVLGSRKG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 178 VNLPGVVVDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVINFDEILRET 257
Cdd:cd00288 160 VNLPGTDVDLPALSEKDKADLR-FGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEAS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 258 DAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAA 337
Cdd:cd00288 239 DGIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 338 GAYPEIAVKVMAKICIEAESSLDYNTIFKEMIRATPLPMSPLESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYRPA 417
Cdd:cd00288 319 GKYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPN 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 418 VPILSVVVpvmttdsfdwscsDESPARHSLIYRGLIPMLAEgSAKATDSEATEVIIEAALKSATQRGLCNRGDAIVALHR 497
Cdd:cd00288 399 APIIAVTR-------------NEQTARQLHLYRGVYPVLFE-EPKPGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQG 464
|
490
....*....|....*.
gi 1063730757 498 I----GAASVIKICVV 509
Cdd:cd00288 465 WpvgsGSTNTMRILTV 480
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
21-509 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 617.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 21 KTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:COG0469 4 RTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG-P 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 101 IQLKEGQEITITTDyDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESgtVRCRCENSAMLGERKNVNL 180
Cdd:COG0469 83 VELKKGDTFTLTTD-DVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDE--VVCEVVNGGVLSSRKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 181 PGVVVDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVINFDEILRETDAF 260
Cdd:COG0469 160 PGVGLSLPALTEKDREDLK-FALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 261 MVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAY 340
Cdd:COG0469 239 MVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 341 PEIAVKVMAKICIEAESSLDYNTIFKEmiRATPLPMSPLESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYRPAVPI 420
Cdd:COG0469 319 PVEAVETMARIAEEAEKSLDYRRILDR--LRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPI 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 421 LSVvvpvmttdsfdwsCSDESPARHSLIYRGLIPMLAEgsakatDSEATEVIIEAALKSATQRGLCNRGDAIV-----AL 495
Cdd:COG0469 397 LAL-------------TPNERTARRLALVWGVYPVLVD------DVESTDEMIEEAVEALLEEGLVKPGDLVVitagvPV 457
|
490
....*....|....
gi 1063730757 496 HRIGAASVIKICVV 509
Cdd:COG0469 458 GVPGTTNTLKVHRV 471
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
19-365 |
0e+00 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 558.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 19 IPKTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDG 98
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 99 -NPIQLKEGQEITITTDYDI--QGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESgTVRCRCENSAMLGER 175
Cdd:pfam00224 81 kKDIELKAGDEMIVSTDAKYkgACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDK-TLVVEVLNGGVIGSR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 176 KNVNLPGVVVDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVINFDEILR 255
Cdd:pfam00224 160 KGVNLPGTDVDLPALSEKDKADLR-FGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 256 ETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGES 335
Cdd:pfam00224 239 ATDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGET 318
|
330 340 350
....*....|....*....|....*....|
gi 1063730757 336 AAGAYPEIAVKVMAKICIEAESSLDYNTIF 365
Cdd:pfam00224 319 AKGNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
21-503 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 549.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 21 KTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:TIGR01064 2 RTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGG-E 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 101 IQLKEGQEITITTDYDIQ-GDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESgtVRCRCENSAMLGERKNVN 179
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKGeGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDK--VICEVLNGGTLKSKKGVN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 180 LPGVVVDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVLGSH-AKSIMLMSKVENQEGVINFDEILRETD 258
Cdd:TIGR01064 159 LPGADVDLPALSEKDKKDLK-FGVEQGVDMVAASFVRTAEDVLEVREVLGEKgAKDVKIIAKIENQEGVDNIDEIAEASD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 259 AFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 338
Cdd:TIGR01064 238 GIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 339 AYPEIAVKVMAKICIEAESSLDYNTIFKEMIRATPLPMSPLESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYRPAV 418
Cdd:TIGR01064 318 KYPVEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 419 PILSVVVpvmttdsfdwscsDESPARHSLIYRGLIPMLAEGSAKATDseateVIIEAALKSATQRGLCNRGDAIVALHRI 498
Cdd:TIGR01064 398 PIIAVTP-------------NERVARQLALYWGVFPFLVDEEPSDTD-----ARVNKALELLKEKGIVKKGDLVVVIQGG 459
|
....*
gi 1063730757 499 GAASV 503
Cdd:TIGR01064 460 PIGGE 464
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
1-510 |
0e+00 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 1088.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 1 MSNIDIEGILKELPNDG-RIPKTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILA 79
Cdd:PLN02461 1 MANIDIEGILKGLPADGlRRPKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 80 AVMLDTKGPEIRTGFLKDGNPIQLKEGQEITITTDYDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPES 159
Cdd:PLN02461 81 AVMLDTKGPEIRTGFLKDGKPVQLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLSCDVEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 160 GTVRCRCENSAMLGERKNVNLPGVVVDLPTLTDKDIEDILGWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIMLMS 239
Cdd:PLN02461 161 GTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDILQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLIS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 240 KVENQEGVINFDEILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 319
Cdd:PLN02461 241 KVENQEGLDNFDDILAESDAFMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 320 NAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKEMIRATPLPMSPLESLASSAVRTANKARAKLII 399
Cdd:PLN02461 321 NAVLDGTDCVMLSGETAAGAYPELAVKTMARICREAEASLDYGALFKEIMRSAPLPMSPLESLASSAVRTANKVKASLIV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 400 VLTRGGSTANLVAKYRPAVPILSVVVPVMTTDSFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDSEATEVIIEAALKS 479
Cdd:PLN02461 401 VLTRGGTTARLVAKYRPAVPILSVVVPEITTDSFDWSCSDEAPARHSLIYRGLIPVLAEGSAKATDSESTEEILEAAIEH 480
|
490 500 510
....*....|....*....|....*....|.
gi 1063730757 480 ATQRGLCNRGDAIVALHRIGAASVIKICVVK 510
Cdd:PLN02461 481 AKKKGLCKPGDSVVALHRIGGASVIKILTVK 511
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
19-509 |
0e+00 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 714.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 19 IPKTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDG 98
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 99 NPIQLKEGQEITITTDY-DIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESgTVRCRCENSAMLGERKN 177
Cdd:cd00288 81 KDISLKAGDKFLVTTDPaAKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDK-TLVCEVLNGGVLGSRKG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 178 VNLPGVVVDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVINFDEILRET 257
Cdd:cd00288 160 VNLPGTDVDLPALSEKDKADLR-FGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEAS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 258 DAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAA 337
Cdd:cd00288 239 DGIMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 338 GAYPEIAVKVMAKICIEAESSLDYNTIFKEMIRATPLPMSPLESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYRPA 417
Cdd:cd00288 319 GKYPVEAVKAMARICLEAEKALSHRVLFNEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPN 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 418 VPILSVVVpvmttdsfdwscsDESPARHSLIYRGLIPMLAEgSAKATDSEATEVIIEAALKSATQRGLCNRGDAIVALHR 497
Cdd:cd00288 399 APIIAVTR-------------NEQTARQLHLYRGVYPVLFE-EPKPGWQEDTDARLKAAVNVAKEKGLLKKGDLVVVVQG 464
|
490
....*....|....*.
gi 1063730757 498 I----GAASVIKICVV 509
Cdd:cd00288 465 WpvgsGSTNTMRILTV 480
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
21-509 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 617.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 21 KTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:COG0469 4 RTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG-P 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 101 IQLKEGQEITITTDyDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESgtVRCRCENSAMLGERKNVNL 180
Cdd:COG0469 83 VELKKGDTFTLTTD-DVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDE--VVCEVVNGGVLSSRKGVNL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 181 PGVVVDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVINFDEILRETDAF 260
Cdd:COG0469 160 PGVGLSLPALTEKDREDLK-FALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 261 MVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAY 340
Cdd:COG0469 239 MVARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKY 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 341 PEIAVKVMAKICIEAESSLDYNTIFKEmiRATPLPMSPLESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYRPAVPI 420
Cdd:COG0469 319 PVEAVETMARIAEEAEKSLDYRRILDR--LRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPI 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 421 LSVvvpvmttdsfdwsCSDESPARHSLIYRGLIPMLAEgsakatDSEATEVIIEAALKSATQRGLCNRGDAIV-----AL 495
Cdd:COG0469 397 LAL-------------TPNERTARRLALVWGVYPVLVD------DVESTDEMIEEAVEALLEEGLVKPGDLVVitagvPV 457
|
490
....*....|....
gi 1063730757 496 HRIGAASVIKICVV 509
Cdd:COG0469 458 GVPGTTNTLKVHRV 471
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
2-499 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 570.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 2 SNIDIEGILKELP-NDGRIPKTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAM----HNTg 76
Cdd:PTZ00066 19 TNISLDKILEPISdNDLRQKKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAkarpNAN- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 77 ilAAVMLDTKGPEIRTGFLKDGNPIQLKEGQEITITTDYDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCd 156
Cdd:PTZ00066 98 --LGILLDTKGPEIRTGFLKNHKPITLKEGQTLKITTDYTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEV- 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 157 pESGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTDKDIEDILGWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIM 236
Cdd:PTZ00066 175 -HDDYIITKVLNNATIGERKNMNLPGVKVELPVIGEKDKNDILNFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIK 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 237 LMSKVENQEGVINFDEILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEAT 316
Cdd:PTZ00066 254 IIPKIENIEGLINFDEILAESDGIMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAEST 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 317 DVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKEMIRATPLPMSPLESLASSAVRTANKARAK 396
Cdd:PTZ00066 334 DVANAVLDGTDCVMLSGETANGKFPVEAVNIMAKICFEAETCIDYRVLYHAIHLAVPTPVSVQEAVARSAVETAEDINAK 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 397 LIIVLTRGGSTANLVAKYRPAVPILSVvvpvmttdsfdwsCSDESPARHSLIYRGLIPMlaegsaKATDSEATEVIIEAA 476
Cdd:PTZ00066 414 LIIALTETGNTARLISKYRPSCTILAL-------------SASPSVVKSLSVARGVTTY------VVNSFQGTDVVIRNA 474
|
490 500
....*....|....*....|...
gi 1063730757 477 LKSATQRGLCNRGDAIVALHRIG 499
Cdd:PTZ00066 475 IALAKERGLVESGDSAIAVHGVK 497
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
19-365 |
0e+00 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 558.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 19 IPKTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDG 98
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 99 -NPIQLKEGQEITITTDYDI--QGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESgTVRCRCENSAMLGER 175
Cdd:pfam00224 81 kKDIELKAGDEMIVSTDAKYkgACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDK-TLVVEVLNGGVIGSR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 176 KNVNLPGVVVDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVINFDEILR 255
Cdd:pfam00224 160 KGVNLPGTDVDLPALSEKDKADLR-FGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILE 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 256 ETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGES 335
Cdd:pfam00224 239 ATDGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGET 318
|
330 340 350
....*....|....*....|....*....|
gi 1063730757 336 AAGAYPEIAVKVMAKICIEAESSLDYNTIF 365
Cdd:pfam00224 319 AKGNYPVEAVRMMHEICLEAEKALPHRNLF 348
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
21-503 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 549.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 21 KTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:TIGR01064 2 RTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGG-E 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 101 IQLKEGQEITITTDYDIQ-GDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESgtVRCRCENSAMLGERKNVN 179
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKGeGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDK--VICEVLNGGTLKSKKGVN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 180 LPGVVVDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVLGSH-AKSIMLMSKVENQEGVINFDEILRETD 258
Cdd:TIGR01064 159 LPGADVDLPALSEKDKKDLK-FGVEQGVDMVAASFVRTAEDVLEVREVLGEKgAKDVKIIAKIENQEGVDNIDEIAEASD 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 259 AFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 338
Cdd:TIGR01064 238 GIMVARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 339 AYPEIAVKVMAKICIEAESSLDYNTIFKEMIRATPLPMSPLESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYRPAV 418
Cdd:TIGR01064 318 KYPVEAVQMMAKIAKEAEKALAYLTNFNDRKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNA 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 419 PILSVVVpvmttdsfdwscsDESPARHSLIYRGLIPMLAEGSAKATDseateVIIEAALKSATQRGLCNRGDAIVALHRI 498
Cdd:TIGR01064 398 PIIAVTP-------------NERVARQLALYWGVFPFLVDEEPSDTD-----ARVNKALELLKEKGIVKKGDLVVVIQGG 459
|
....*
gi 1063730757 499 GAASV 503
Cdd:TIGR01064 460 PIGGE 464
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
21-493 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 517.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 21 KTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:PRK05826 5 RTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG-K 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 101 IQLKEGQEITITTDYDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPEsgTVRCRCENSAMLGERKNVNL 180
Cdd:PRK05826 84 ITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGD--EVETEVKNGGPLSNNKGINI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 181 PGVVVDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVL----GSHAKsimLMSKVENQEGVINFDEILRE 256
Cdd:PRK05826 162 PGGGLSLPALTEKDKADIK-FAAEQGVDYIAVSFVRSAEDVEEARRLLreagCPHAK---IIAKIERAEAVDNIDEIIEA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 257 TDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESA 336
Cdd:PRK05826 238 SDGIMVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 337 AGAYPEIAVKVMAKICIEAESSLDYNTIFKEMIRATplpMSPLESLASSAVRTANK-ARAKLIIVLTRGGSTANLVAKYR 415
Cdd:PRK05826 318 AGKYPVEAVEAMARICKGAEKEFSINLSKHRLDRQF---DRIDEAIAMSAMYAANHlKGVKAIVALTESGRTARLISRFR 394
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063730757 416 PAVPILSVvvpvmttdsfdwsCSDESPARHSLIYRGLIPMLAEGSAKatdseaTEVIIEAALKSATQRGLCNRGDAIV 493
Cdd:PRK05826 395 PGAPIFAV-------------TRDEKTQRRLALYRGVYPVLFDSAAD------TDDAAEEALRLLLEKGLVESGDLVV 453
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
9-506 |
8.13e-179 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 512.68 E-value: 8.13e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 9 ILKELPnDGRIPK-TKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKG 87
Cdd:PLN02765 17 ILEPSK-PSFFPAlTKIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 88 PEIRTgFLKDGNPIQLKEGQEITITTDYDIQGDESTISMSYKKLPLDVKPGNTILCAD----GSISLAV-LSCDPESGT- 161
Cdd:PLN02765 96 PELQV-INKTEKPISLKAGNTVTLTPDQSKEASSEVLPINFPGLAKAVKPGDTIFVGQylftGSETTSVwLEVDEVKGDd 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 162 VRCRCENSAML-GERKNVNLPGVVVDLPTLTDKDIEDILGWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHA-KSIMLMS 239
Cdd:PLN02765 175 VVCTVKNSATLaGSLFTLHVSQVRIDLPTLSEKDKEVISTWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGlSQTQIFA 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 240 KVENQEGVINFDEILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTaTQMLESMIKSPRPTRAEATDVA 319
Cdd:PLN02765 255 KIENVEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVA 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 320 NAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKEMIRATPLPMSPLESLASSAVRTANKARAKLII 399
Cdd:PLN02765 334 NAVLDGADAILLGAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKKTVKYVGEPMSHLESIASSAVRAAIKVKASVII 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 400 VLTRGGSTANLVAKYRPAVPILSVVVPVMTTDSFDWSCSDESPARHSLIYRGLIPMLAEGSAKATDSEAT-EVIIEAALK 478
Cdd:PLN02765 414 VFTSSGRAARLIAKYRPTMPVLSVVIPRLKTNQLKWSFTGAFQARQCLIVRGLFPMLADPRHSAESTSATnESVLKVALD 493
|
490 500
....*....|....*....|....*...
gi 1063730757 479 SATQRGLCNRGDAIVALHRIGAASVIKI 506
Cdd:PLN02765 494 HGKAAGVIKSHDRVVVCQKVGDSSVVKI 521
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
21-493 |
1.25e-174 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 499.97 E-value: 1.25e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 21 KTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDGNP 100
Cdd:PRK09206 3 KTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGGND 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 101 IQLKEGQEITITTDYDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCdpESGTVRCRCENSAMLGERKNVNL 180
Cdd:PRK09206 83 VSLKAGQTFTFTTDKSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAI--TGNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 181 PGVVVDLPTLTDKDIEDiLGWGVPNSIDMIALSFVRKGSDLVNVRKVLGSH-AKSIMLMSKVENQEGVINFDEILRETDA 259
Cdd:PRK09206 161 PGVSIALPALAEKDKQD-LIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHgGENIQIISKIENQEGLNNFDEILEASDG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 260 FMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGA 339
Cdd:PRK09206 240 IMVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 340 YPEIAVKVMAKICIEAE----SSLDYNTIFKEMiRATplpmsplESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYR 415
Cdd:PRK09206 320 YPLEAVSIMATICERTDrvmnSRLESNNDNRKL-RIT-------EAVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYF 391
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063730757 416 PAVPILSVvvpvmTTdsfdwscsDESPARHSLIYRGLIPMLAEGSAKatdseaTEVIIEAALKSATQRGLCNRGDAIV 493
Cdd:PRK09206 392 PDATILAL-----TT--------NEKTARQLVLSKGVVPQLVKEIAS------TDDFYRLGKELALQSGLAQKGDVVV 450
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
21-493 |
5.72e-154 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 451.69 E-value: 5.72e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 21 KTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:PRK06354 9 RTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDG-P 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 101 IQLKEGQEITITTDyDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESGTVRCRCENSAMLGERKNVNL 180
Cdd:PRK06354 88 IELKTGDEFILTSR-EVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKADGELHCKVLVGGVLSNKKGVNF 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 181 PGVVVDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVLGSH-AKSIMLMSKVENQEGVINFDEILRETDA 259
Cdd:PRK06354 167 PGVSLSLPAITEKDREDLI-FGLEQGVDWIALSFVRNPSDVLEIRELIEEHnGKHIPIIAKIEKQEAIDNIDAILELCDG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 260 FMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGA 339
Cdd:PRK06354 246 LMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAGD 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 340 YPEIAVKVMAKICIEAESSLDYNTIFKEMiraTPLPMSPLESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYRPAVP 419
Cdd:PRK06354 326 YPVEAVQTMATIAVRIEKDLPYRDILSKR---PEFTTTITNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRPKTP 402
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063730757 420 ILSVVvpvmttdsfdwscSDESPARH-SLIYrGLIPMLAEgsakatDSEATEVIIEAALKSATQRGLCNRGDAIV 493
Cdd:PRK06354 403 ILAVT-------------PNESVARRlQLVW-GVTPLLVL------DAPSTDETFDAAINVAQESGLLKQGDLVV 457
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
46-496 |
6.93e-144 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 421.00 E-value: 6.93e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 46 MNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDGNPIqLKEGQEITITTD--YDIQGDEST 123
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAV-MERGATCYVTTDpaFADKGTKDK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 124 ISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESgTVRCRCENSAMLGERKNVNLPGVVVDLPTLTDKDIEDiLGWGV 203
Cdd:PTZ00300 80 FYIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEQ-TLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCAD-LQFGV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 204 PNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVINFDEILRETDAFMVARGDLGMEIPIEKIFLAQKLM 283
Cdd:PTZ00300 158 EQGVDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKIL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 284 IYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNT 363
Cdd:PTZ00300 238 ISKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNEYV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 364 IFKEMIRATPLPMSPLESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYRPAVPILSVVVPVMTtdsfdwscsdespA 443
Cdd:PTZ00300 318 FFNSIKKLQPIPMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQT-------------C 384
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 1063730757 444 RHSLIYRGLIPMLAEGSAKATDsEATEVIIEAALKSATQRGLCNRGDAIVALH 496
Cdd:PTZ00300 385 RQLNITQGVESVFFDAERLGHD-EGKEQRVAMGVGFAKSKGYVQSGDLMVVVH 436
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
21-493 |
3.12e-136 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 402.38 E-value: 3.12e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 21 KTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDGnP 100
Cdd:PRK06247 6 RVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFADG-K 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 101 IQLKEGQEITITTDyDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESgtVRCRCENSAMLGERKNVNL 180
Cdd:PRK06247 85 VQLANGQTFRLDVD-DAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDD--VVCRVVEGGPVSDRKGVSL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 181 PGVVVDLPTLTDKDIEDiLGWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKsimLMSKVENQEGVINFDEILRETDAF 260
Cdd:PRK06247 162 PGTVLSVSALTEKDRAD-LEFALELGVDWVALSFVQRPEDVEEVRKIIGGRVP---VMAKIEKPQAIDRLEAIVEASDAI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 261 MVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAY 340
Cdd:PRK06247 238 MVARGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKY 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 341 PEIAVKVMAKICIEAESSLDYNTIfkemiraTPLPMSPLESLASSAV-----RTANKARAKLIIVLTRGGSTANLVAKYR 415
Cdd:PRK06247 318 PVEAVRTMARIIRQVERDPTYPPL-------IHAQRPQPEATKRDAIsyaarDIAERLDLAALVAYTSSGDTALRAARER 390
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063730757 416 PAVPILsVVVPVMTTDSfdwscsdespaRHSLIYrGLIPMLAEgsakatDSEATEVIIEAALKSATQRGLCNRGDAIV 493
Cdd:PRK06247 391 PPLPIL-ALTPNPETAR-----------RLALTW-GVHCVVVD------DARDTDDMVRRADRIALAEGFYKRGDRVV 449
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
21-503 |
5.95e-105 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 325.34 E-value: 5.95e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 21 KTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLR--SAMHNTGILAaVMLDTKGPEIRTGFLKDg 98
Cdd:PLN02623 111 KTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKeyNAQSKDNVIA-IMLDTKGPEVRSGDLPQ- 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 99 nPIQLKEGQEITITTDYDIqGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLScdPESGTVRCRCENSAMLGERKNV 178
Cdd:PLN02623 189 -PIMLEEGQEFTFTIKRGV-STEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKS--KTSDSVKCEVVDGGELKSRRHL 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 179 NLPGVVVDLPTLTDKDIEDIlGWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAKSIMLMSKVENQEGVINFDEILRETD 258
Cdd:PLN02623 265 NVRGKSATLPSITEKDWEDI-KFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESADSIPNLHSIITASD 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 259 AFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAG 338
Cdd:PLN02623 344 GAMVARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHG 423
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 339 AYPEIAVKVMAKICIEAESSLDYNTIFKEMIRATPLPMSplESLASSAVRTANKARAKlIIVLTRGGSTANLVAKYRPAV 418
Cdd:PLN02623 424 KFPLKAVKVMHTVALRTEATLPEGTTPPNLGQAFKNHMS--EMFAFHATMMANTLGTS-IIVFTRTGFMAILLSHYRPSG 500
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 419 PILSVVvpvmttdsfdwscSDESPARHSLIYRGLIPMLAEGSAKATDSEATeviieaALKSATQRGLCNRGDAiVALHRI 498
Cdd:PLN02623 501 TIFAFT-------------NEKRIQQRLALYQGVCPIYMQFSDDAEETFAR------ALSLLLNKGMVKEGEE-VALVQS 560
|
....*
gi 1063730757 499 GAASV 503
Cdd:PLN02623 561 GRQPI 565
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
25-356 |
2.48e-85 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 267.20 E-value: 2.48e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 25 VCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAavmlDTKGPEIRTGFLKdGNPIQLK 104
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDDSIKILG----DVQGPKIRLGEIK-GEQITLQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 105 EGQEITITTDyDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLSCdpESGTVRCRCENSAMLGERKNVNLPGVV 184
Cdd:PRK06739 81 AGDSFILHTQ-PVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKV--STDKIETKVKTGGNISSHKGVNLPGAI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 185 VDLPTLTDKDIEDILgWGVPNSIDMIALSFVRKGSDLVNVRKVLGSHAK-SIMLMSKVENQEGVINFDEILRETDAFMVA 263
Cdd:PRK06739 158 VRLPAITEKDKKDIQ-FLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKEtSPNLIAKIETMEAIENFQDICKEADGIMIA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 264 RGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPEI 343
Cdd:PRK06739 237 RGDLGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIE 316
|
330
....*....|...
gi 1063730757 344 AVKVMAKICIEAE 356
Cdd:PRK06739 317 SVSTLRLVSEFAE 329
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
21-510 |
1.18e-84 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 270.46 E-value: 1.18e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 21 KTKIVCTLGPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDGNP 100
Cdd:PLN02762 26 RTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDLGGASS 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 101 IQLKEGQEITITT-DYDIQGDESTISMSYKKLPLDVKPGNTILCADGSISLAVLscDPESGTVRCRCENSAMLGERKNVN 179
Cdd:PLN02762 106 AKAEDGEEWTFTVrKFDGSRPEFTIQVNYDGFAEDVKVGDELVVDGGMVRFEVI--EKIGPDVKCKCTDPGLLLPRANLT 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 180 L--PGVVVD-----LPTLTDKDIEDIlGWGVPNSIDMIALSFVRKGSDLVNVRKVLG--SHAKSIMLMSKVENQEGVINF 250
Cdd:PLN02762 184 FwrDGSLVRernamLPTISSKDWLDI-DFGISEGVDFIAVSFVKSAEVIKHLKSYIAarSRDSDIGVIAKIESLDSLKNL 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 251 DEILRETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVM 330
Cdd:PLN02762 263 EEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQRADALM 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 331 LSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIFKEMIR---ATPLPMSPLESLASSAVRTANKARAKLIIVLTRGGST 407
Cdd:PLN02762 343 LSGESAMGLYPEKALSVLRSVSLRMELWSREEKRHEALELpqlSSSLSDRISEEICNSAAKMANNLGVDAIFVYTKHGHM 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 408 ANLVAKYRPAVPILSVvvpvmttdsfdwscSDESPARHSL-IYRGLIPMLAEGSakaTDSEATEVIIEAALKSatqRGLC 486
Cdd:PLN02762 423 ASLLSRNRPDCPIFAF--------------TDTTSVRRRLnLQWGLIPFRLDFS---DDMESNLNKTFSLLKA---RGMI 482
|
490 500
....*....|....*....|....
gi 1063730757 487 NRGDAIVALHRIGAASVIKICVVK 510
Cdd:PLN02762 483 KSGDLVIAVSDLTPSSMLQSIQVR 506
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
286-493 |
6.80e-41 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 149.67 E-value: 6.80e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 286 KCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGESAAGAYPEIAVKVMAKICIEAESSLDYNTIF 365
Cdd:COG3848 1 KCNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 366 KEmiRATPLPMSPLESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYRPAVPILSVvvpvmtTDSfdwscsdESPARH 445
Cdd:COG3848 81 VP--RAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAV------TPS-------ERVARQ 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1063730757 446 SLIYRGLIPMLAEgsakatDSEATEVIIEAALKSATQRGLCNRGDAIV 493
Cdd:COG3848 146 LSLVWGVYPLLVE------ESASTDEMFAVAVALALEAGLVKDGDLVV 187
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
20-331 |
2.32e-39 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 149.39 E-value: 2.32e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 20 PKTKIVCTL-GPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDG 98
Cdd:PRK08187 133 RRTRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAVAGP 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 99 NPIQ-LKEGQEITITTDYDIQGDEST---ISMSYKKLPLDVKPGNTILCADGSISLAVLSCDPESGTVR---CRcENSAM 171
Cdd:PRK08187 213 LGKTrLYTGDRLALVAQGPPRRIDEEhfqVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGALLEvthAR-PKGLK 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 172 LGERKNVNLPGVVVDLPTLTDKDIEDiLGWgVPNSIDMIALSFVRKGSDL------VNVRKVLGSHAKSIMLmsKVENQE 245
Cdd:PRK08187 292 LKPEKGLNFPDTALDLPALTEKDRAD-LDF-VARHADLVGYSFVQSPGDVealqaaLAARRPDDWRKLGLVL--KIETPR 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 246 GVINFDEIL-----RETDAFMVARGDLGMEIPIEKIFLAQKLMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVAN 320
Cdd:PRK08187 368 AVANLPELIvqaagRQPFGVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAM 447
|
330
....*....|.
gi 1063730757 321 AvlDGTDCVML 331
Cdd:PRK08187 448 A--ARAECVML 456
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
22-351 |
5.18e-32 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 129.68 E-value: 5.18e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 22 TKIVCTL-GPASRTVSMIEKLLKAGMNVARFNFSHGSHEYHQETLDNLRSAMHNTGILAAVMLDTKGPEIRTGFLKDG-- 98
Cdd:PRK14725 141 TRIMVTLpTEAADDPDLVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGRRCRIAMDLAGPKLRTGPIAPGpr 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 --------------------------------------------------------------------------------
Cdd:PRK14725 221 viklrptrdalgrvltparlwltasespppspppgpvglpvdpewlarlepgdelrftdargkkrkltvtevddegvlae 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 99 ------------------------------NPIQLKEGQEITITTDyDIQGD-------ESTISMSYKKLPLDVKPGNTI 141
Cdd:PRK14725 301 gsqtaylangtllrlgrhdstrvgglppveQKLRLKVGDRLVLTRD-DAPGDpaqgdapPARISCTLPEAFRAARVGERV 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 142 LCADGSISLAVLSCDPESGTVR---CRCENSAmLGERKNVNLPGVVVDLPTLTDKDIEDiLGWGVPNSiDMIALSFVRKG 218
Cdd:PRK14725 380 WFDDGKIGAVVVKVEADEVELRithARPGGSK-LKAGKGINLPDSHLPLPALTDKDLED-LAFVAKHA-DIVALSFVRSP 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 219 SDLVNVRKVLGSH-AKSIMLMSKVENQEGVINFDEILRETDAF-----MVARGDLGMEIPIEKIFLAQKLMIYKCNLAGK 292
Cdd:PRK14725 457 EDVRLLLDALEKLgADDLGVVLKIETRRAFENLPRILLEAMRHprfgvMIARGDLAVEVGFERLAEVQEEILWLCEAAHV 536
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 1063730757 293 PVVTATQMLESMIKSPRPTRAEATDVANAVLdgTDCVMLSgesaAGAYPEIAVKVMAKI 351
Cdd:PRK14725 537 PVIWATQVLESLAKKGLPSRAEITDAAMALR--AECVMLN----KGPHIVEAVRVLDDI 589
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
380-506 |
1.19e-22 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 92.93 E-value: 1.19e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063730757 380 ESLASSAVRTANKARAKLIIVLTRGGSTANLVAKYRPAVPILSVvvpvmttdsfdwsCSDESPARHSLIYRGLIPMLAEg 459
Cdd:pfam02887 1 EAIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAV-------------TPNELTARQLALYWGVYPVLFD- 66
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1063730757 460 sakatDSEATEVIIEAALKSATQRGLCNRGDAIVALHRI-----GAASVIKI 506
Cdd:pfam02887 67 -----EAETTDEMLRRAVKVAKEAGLVKKGDLVVITAGVpfgvsGTTNTLKV 113
|
|
| |
