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histone deacetylase complex subunit SAP130 isoform c [Homo sapiens]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
SAP130_C
pfam16014 Histone deacetylase complex subunit SAP130 C-terminus;
634-1039
0e+00
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain]
Cd Length: 371
Bit Score: 556.85
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 634 A Q GSSPRPSILRKKPAT D G mavrktlippqppdvasprvessmrstsgsprpag AKPK SE IHV SM A T PVTV SM E TVSN QN 713
Cdd:pfam16014 1 A L GSSPRPSILRKKPAT E G ----------------------------------- AKPK PD IHV AV A P PVTV AV E ALPG QN 45
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 714 ND Q P T IAVP P TA Q Q P PPT IPT MI A A A S PPSQP A V A LST I P G A VPI TPPI T --- TIAA APP PSVTVGGSLSSVLGPPV PEI 790
Cdd:pfam16014 46 SE Q Q T ASAS P PS Q H P AQA IPT IL A P A A PPSQP S V V LST L P A A MAV TPPI P asm ANVV APP TQPAASSTAACAVSSVL PEI 125
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 791 K V K E E V EPMD IMR pvs A VPPL ATNTV SP S L AL LANNLS M P TS DL P PGASPRKKPRKQQHVISTEEG D MMETNSTD D EKS T 870
Cdd:pfam16014 126 K I K Q E A EPMD TSQ --- S VPPL TPTSI SP A L TS LANNLS V P AG DL L PGASPRKKPRKQQHVISTEEG E MMETNSTD E EKS A 202
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 871 A K S L LVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK AM LQ EI ANQKGV S CR 950
Cdd:pfam16014 203 P K P L TSR AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK GT LQ DM ANQKGV T CR 282
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 951 AQGWK V HLCAAQLLQLTNLEHDVY E RLT N LQEG I IPKKKA A TDDDLHRINELIQGNMQRCKLVMDQI S EARDSM L KVLDH 1030
Cdd:pfam16014 283 AQGWK I HLCAAQLLQLTNLEHDVY S RLT T LQEG L IPKKKA G TDDDLHRINELIQGNMQRCKLVMDQI T EARDSM M KVLDH 362
....*....
gi 1057866215 1031 KDRVLKLLN 1039
Cdd:pfam16014 363 KDRVLKLLN 371
Atrophin-1 super family
cl38111 Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
439-820
7.17e-05
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
pfam03154 :Pssm-ID: 460830 [Multi-domain]
Cd Length: 991
Bit Score: 47.07
E-value: 7.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 439 P N P VAM E TR SD NRPSVPVQFQYFLPTYPP S AYPLAAHTYT P I T SSVS T IRQY P VSAQA P NSAIT A QTGVGVASTVHLN P M 518
Cdd:pfam03154 149 P S P QDN E SD SD SSAQQQILQTQPPVLQAQ S GAASPPSPPP P G T TQAA T AGPT P SAPSV P PQGSP A TSQPPNQTQSTAA P H 228
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 519 Q L MTVDAS ha R H I Q GI q P A P ISTQGIQPA P IGTPGIQ P A PL GTQGI H SAT P INTQG LQ PA P MGT Q Q P Q P E gktsavvlad 598
Cdd:pfam03154 229 T L IQQTPT -- L H P Q RL - P S P HPPLQPMTQ P PPPSQVS P Q PL PQPSL H GQM P PMPHS LQ TG P SHM Q H P V P P ---------- 295
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 599 g ATIVAN P I S NPFSAA P AATTVVQTH SQ SASTNA P A Q GSSPRPSIL R KK P ATDGMAVRKTLI PP --------------- Q 663
Cdd:pfam03154 296 - QPFPLT P Q S SQSQVP P GPSPAAPGQ SQ QRIHTP P S Q SQLQSQQPP R EQ P LPPAPLSMPHIK PP pttpipqlpnpqshk H 374
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 664 PP DVAS P rve S SMRST S GS P R P AGA KP K S EI --- H VSM A T P VTVSMETV S N Q ---- NNDQ P TIAVPPTAQQ P PPTI P TMI 736
Cdd:pfam03154 375 PP HLSG P --- S PFQMN S NL P P P PAL KP L S SL sth H PPS A H P PPLQLMPQ S Q Q lppp PAQP P VLTQSQSLPP P AASH P PTS 451
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 737 AAASP PSQ PAVAL - STI PG AV P - ITPP ITTIAAAPP ---------- P SV TVG G SLSSVLGP P V P EIKV KEE v EPMDIMR P 804
Cdd:pfam03154 452 GLHQV PSQ SPFPQ h PFV PG GP P p ITPP SGPPTSTSS ampgiqppss A SV SSS G PVPAAVSC P L P PVQI KEE - ALDEAEE P 530
410
....*....|....*.
gi 1057866215 805 V S AV PP LATNTVS P SL 820
Cdd:pfam03154 531 E S PP PP PRSPSPE P TV 546
PHA03247 super family
cl33720 large tegument protein UL36; Provisional
19-396
2.23e-04
large tegument protein UL36; Provisional
PHA03247 :Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 45.70
E-value: 2.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 19 A PS QIANSGSAGLIN P AATVND E SG RD SEVSA R EHMSSSSSLQS R EEKQEPVVV RP YPQVQMLSTHHAVAS A T P VAVTAP 98
Cdd:PHA03247 2628 P PS PSPAANEPDPHP P PTVPPP E RP RD DPAPG R VSRPRRARRLG R AAQASSPPQ RP RRRAARPTVGSLTSL A D P PPPPPT 2707
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 99 P AHLTP A VPLSFSEGLMKPPPKPTM P SR P I APAPP STLS l P P KV PG QVTVTMESSIPQASAI P VATISGQQ G H P SN L HHI 178
Cdd:PHA03247 2708 P EPAPH A LVSATPLPPGPAAARQAS P AL P A APAPP AVPA - G P AT PG GPARPARPPTTAGPPA P APPAAPAA G P P RR L TRP 2786
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 179 MTTNVQM S IIRSNA P GP P LHIG A SH L PR gaaaaavms SSKVTTVLR P TSQ LP NAAT AQP AVQHIIHQ P IQSRP P VTT S N A 258
Cdd:PHA03247 2787 AVASLSE S RESLPS P WD P ADPP A AV L AP --------- AAALPPAAS P AGP LP PPTS AQP TAPPPPPG P PPPSL P LGG S V A 2857
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 259 -------- I P PAVV A TVS A TR A QS PV ITTTA --- AHA T D S ALR P TLSIQH PP SAAISIQRPA Q SRDVTTRITL P SH P ALG 327
Cdd:PHA03247 2858 pggdvrrr P P SRSP A AKP A AP A RP PV RRLAR pav SRS T E S FAL P PDQPER PP QPQAPPPPQP Q PQPPPPPQPQ P PP P PPP 2937
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1057866215 328 T P KQQ L HTMAQKTIFSTGTPVAAATVAPI L ATNTIP ----- SATT A G S VSHTQAP T STIVTMTVPSH SS H A TAV 396
Cdd:PHA03247 2938 R P QPP L APTTDPAGAGEPSGAVPQPWLGA L VPGRVA vprfr VPQP A P S REAPASS T PPLTGHSLSRV SS W A SSL 3011
Name
Accession
Description
Interval
E-value
SAP130_C
pfam16014 Histone deacetylase complex subunit SAP130 C-terminus;
634-1039
0e+00
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain]
Cd Length: 371
Bit Score: 556.85
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 634 A Q GSSPRPSILRKKPAT D G mavrktlippqppdvasprvessmrstsgsprpag AKPK SE IHV SM A T PVTV SM E TVSN QN 713
Cdd:pfam16014 1 A L GSSPRPSILRKKPAT E G ----------------------------------- AKPK PD IHV AV A P PVTV AV E ALPG QN 45
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 714 ND Q P T IAVP P TA Q Q P PPT IPT MI A A A S PPSQP A V A LST I P G A VPI TPPI T --- TIAA APP PSVTVGGSLSSVLGPPV PEI 790
Cdd:pfam16014 46 SE Q Q T ASAS P PS Q H P AQA IPT IL A P A A PPSQP S V V LST L P A A MAV TPPI P asm ANVV APP TQPAASSTAACAVSSVL PEI 125
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 791 K V K E E V EPMD IMR pvs A VPPL ATNTV SP S L AL LANNLS M P TS DL P PGASPRKKPRKQQHVISTEEG D MMETNSTD D EKS T 870
Cdd:pfam16014 126 K I K Q E A EPMD TSQ --- S VPPL TPTSI SP A L TS LANNLS V P AG DL L PGASPRKKPRKQQHVISTEEG E MMETNSTD E EKS A 202
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 871 A K S L LVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK AM LQ EI ANQKGV S CR 950
Cdd:pfam16014 203 P K P L TSR AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK GT LQ DM ANQKGV T CR 282
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 951 AQGWK V HLCAAQLLQLTNLEHDVY E RLT N LQEG I IPKKKA A TDDDLHRINELIQGNMQRCKLVMDQI S EARDSM L KVLDH 1030
Cdd:pfam16014 283 AQGWK I HLCAAQLLQLTNLEHDVY S RLT T LQEG L IPKKKA G TDDDLHRINELIQGNMQRCKLVMDQI T EARDSM M KVLDH 362
....*....
gi 1057866215 1031 KDRVLKLLN 1039
Cdd:pfam16014 363 KDRVLKLLN 371
PHA03247
PHA03247 large tegument protein UL36; Provisional
536-885
3.04e-07
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 54.94
E-value: 3.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 536 P A P ISTQGIQ PA PIGT P GIQPA P L G T qgihs ATP I -- NTQGLQ P APM G TQQ P Q P ----- E G KTSAVVLADG A TIVANPI S 608
Cdd:PHA03247 2723 P G P AAARQAS PA LPAA P APPAV P A G P ----- ATP G gp ARPARP P TTA G PPA P A P paapa A G PPRRLTRPAV A SLSESRE S 2797
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 609 N P FSAA PA ATTVVQTHSQS A -- STNA PA QGSS P RP S ILRKK P AT dgmavrk TLI PP Q P PDV ---- AS P RVESSM R ST S G S 682
Cdd:PHA03247 2798 L P SPWD PA DPPAAVLAPAA A lp PAAS PA GPLP P PT S AQPTA P PP ------- PPG PP P P SLP lggs VA P GGDVRR R PP S R S 2870
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 683 P RPAG A K P KSEIHVSM A T P VT vsme TV S NQNNDQ P TIAVPPTA Q QPP P TI P TMIAAAS PP S QP AVALSTI P GAV P ITP P I 762
Cdd:PHA03247 2871 P AAKP A A P ARPPVRRL A R P AV ---- SR S TESFAL P PDQPERPP Q PQA P PP P QPQPQPP PP P QP QPPPPPP P RPQ P PLA P T 2946
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 763 T TI A A A PP PS VT V GGSLSSV L G P --- P VP EIK V KEEVEPMDI mr P V S AV PPL a T NTVSPSLALL A NN L SMPTSDL PP GA S 839
Cdd:PHA03247 2947 T DP A G A GE PS GA V PQPWLGA L V P grv A VP RFR V PQPAPSREA -- P A S ST PPL - T GHSLSRVSSW A SS L ALHEETD PP PV S 3023
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1057866215 840 prkkp R KQ QHVIS -- TE EG D MMETNST D D E K S TAKS L LVKAEKRKS P P 885
Cdd:PHA03247 3024 ----- L KQ TLWPP dd TE DS D ADSLFDS D S E R S DLEA L DPLPPEPHD P F 3066
Atrophin-1
pfam03154 Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
439-820
7.17e-05
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain]
Cd Length: 991
Bit Score: 47.07
E-value: 7.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 439 P N P VAM E TR SD NRPSVPVQFQYFLPTYPP S AYPLAAHTYT P I T SSVS T IRQY P VSAQA P NSAIT A QTGVGVASTVHLN P M 518
Cdd:pfam03154 149 P S P QDN E SD SD SSAQQQILQTQPPVLQAQ S GAASPPSPPP P G T TQAA T AGPT P SAPSV P PQGSP A TSQPPNQTQSTAA P H 228
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 519 Q L MTVDAS ha R H I Q GI q P A P ISTQGIQPA P IGTPGIQ P A PL GTQGI H SAT P INTQG LQ PA P MGT Q Q P Q P E gktsavvlad 598
Cdd:pfam03154 229 T L IQQTPT -- L H P Q RL - P S P HPPLQPMTQ P PPPSQVS P Q PL PQPSL H GQM P PMPHS LQ TG P SHM Q H P V P P ---------- 295
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 599 g ATIVAN P I S NPFSAA P AATTVVQTH SQ SASTNA P A Q GSSPRPSIL R KK P ATDGMAVRKTLI PP --------------- Q 663
Cdd:pfam03154 296 - QPFPLT P Q S SQSQVP P GPSPAAPGQ SQ QRIHTP P S Q SQLQSQQPP R EQ P LPPAPLSMPHIK PP pttpipqlpnpqshk H 374
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 664 PP DVAS P rve S SMRST S GS P R P AGA KP K S EI --- H VSM A T P VTVSMETV S N Q ---- NNDQ P TIAVPPTAQQ P PPTI P TMI 736
Cdd:pfam03154 375 PP HLSG P --- S PFQMN S NL P P P PAL KP L S SL sth H PPS A H P PPLQLMPQ S Q Q lppp PAQP P VLTQSQSLPP P AASH P PTS 451
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 737 AAASP PSQ PAVAL - STI PG AV P - ITPP ITTIAAAPP ---------- P SV TVG G SLSSVLGP P V P EIKV KEE v EPMDIMR P 804
Cdd:pfam03154 452 GLHQV PSQ SPFPQ h PFV PG GP P p ITPP SGPPTSTSS ampgiqppss A SV SSS G PVPAAVSC P L P PVQI KEE - ALDEAEE P 530
410
....*....|....*.
gi 1057866215 805 V S AV PP LATNTVS P SL 820
Cdd:pfam03154 531 E S PP PP PRSPSPE P TV 546
PHA03247
PHA03247 large tegument protein UL36; Provisional
19-396
2.23e-04
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 45.70
E-value: 2.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 19 A PS QIANSGSAGLIN P AATVND E SG RD SEVSA R EHMSSSSSLQS R EEKQEPVVV RP YPQVQMLSTHHAVAS A T P VAVTAP 98
Cdd:PHA03247 2628 P PS PSPAANEPDPHP P PTVPPP E RP RD DPAPG R VSRPRRARRLG R AAQASSPPQ RP RRRAARPTVGSLTSL A D P PPPPPT 2707
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 99 P AHLTP A VPLSFSEGLMKPPPKPTM P SR P I APAPP STLS l P P KV PG QVTVTMESSIPQASAI P VATISGQQ G H P SN L HHI 178
Cdd:PHA03247 2708 P EPAPH A LVSATPLPPGPAAARQAS P AL P A APAPP AVPA - G P AT PG GPARPARPPTTAGPPA P APPAAPAA G P P RR L TRP 2786
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 179 MTTNVQM S IIRSNA P GP P LHIG A SH L PR gaaaaavms SSKVTTVLR P TSQ LP NAAT AQP AVQHIIHQ P IQSRP P VTT S N A 258
Cdd:PHA03247 2787 AVASLSE S RESLPS P WD P ADPP A AV L AP --------- AAALPPAAS P AGP LP PPTS AQP TAPPPPPG P PPPSL P LGG S V A 2857
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 259 -------- I P PAVV A TVS A TR A QS PV ITTTA --- AHA T D S ALR P TLSIQH PP SAAISIQRPA Q SRDVTTRITL P SH P ALG 327
Cdd:PHA03247 2858 pggdvrrr P P SRSP A AKP A AP A RP PV RRLAR pav SRS T E S FAL P PDQPER PP QPQAPPPPQP Q PQPPPPPQPQ P PP P PPP 2937
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1057866215 328 T P KQQ L HTMAQKTIFSTGTPVAAATVAPI L ATNTIP ----- SATT A G S VSHTQAP T STIVTMTVPSH SS H A TAV 396
Cdd:PHA03247 2938 R P QPP L APTTDPAGAGEPSGAVPQPWLGA L VPGRVA vprfr VPQP A P S REAPASS T PPLTGHSLSRV SS W A SSL 3011
PRK07764
PRK07764 DNA polymerase III subunits gamma and tau; Validated
250-656
1.59e-03
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain]
Cd Length: 824
Bit Score: 42.67
E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 250 R PPVTTSN A IP PA VV A TVS A TR A QSPVITTT AA HATDS A LRPTLSIQH P PS A AISIQR P AQSRDVTTRITL PS H P ALGT P 329
Cdd:PRK07764 383 R RLGVAGG A GA PA AA A PSA A AA A PAAAPAPA AA APAAA A APAPAAAPQ P AP A PAPAPA P PSPAGNAPAGGA PS P P PAAA P 462
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 330 KQ Q LHTMAQKTIFS T GT P VA A ATV AP il A TNTI P S A TT A GSVSHTQAPTS T I ------ VTMT VP SH S SHAT A VTTSNIP V 403
Cdd:PRK07764 463 SA Q PAPAPAAAPEP T AA P AP A PPA AP -- A PAAA P A A PA A PAAPAGADDAA T L rerwpe ILAA VP KR S RKTW A ILLPEAT V 540
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 404 AK V VPQQ -- ITHTSP ---- R I - Q P DYPAE - RSS L IPIS G HRASPNP V AMETRSDNRPSV P VQFQYFL P TYP --- P S A YPL 472
Cdd:PRK07764 541 LG V RGDT lv LGFSTG glar R F a S P GNAEV l VTA L AEEL G GDWQVEA V VGPAPGAAGGEG P PAPASSG P PEE aar P A A PAA 620
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 473 A A HTYT P ITSSVSTIRQYPVS A Q AP NS A ITAQTGVG VA ST vhl NPMQLMTVDASH A RHIQGIQ P A P ISTQGIQP AP I G TP 552
Cdd:PRK07764 621 P A APAA P APAGAAAAPAEASA A P AP GV A APEHHPKH VA VP --- DASDGGDGWPAK A GGAAPAA P P P APAPAAPA AP A G AA 697
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 553 GI QPAP LGTQGIHSATPINTQGLQ P APMGTQQPQPEGKTSA V V L ADGAT iv AN P ISNPFS A A P AATTVVQTHSQS A STNA 632
Cdd:PRK07764 698 PA QPAP APAATPPAGQADDPAAQP P QAAQGASAPSPAADDP V P L PPEPD -- DP P DPAGAP A Q P PPPPAPAPAAAP A AAPP 775
410 420
....*....|....*....|....
gi 1057866215 633 P AQG S SPRPSILRKK P AT D GMAV R 656
Cdd:PRK07764 776 P SPP S EEEEMAEDDA P SM D DEDR R 799
Name
Accession
Description
Interval
E-value
SAP130_C
pfam16014 Histone deacetylase complex subunit SAP130 C-terminus;
634-1039
0e+00
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain]
Cd Length: 371
Bit Score: 556.85
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 634 A Q GSSPRPSILRKKPAT D G mavrktlippqppdvasprvessmrstsgsprpag AKPK SE IHV SM A T PVTV SM E TVSN QN 713
Cdd:pfam16014 1 A L GSSPRPSILRKKPAT E G ----------------------------------- AKPK PD IHV AV A P PVTV AV E ALPG QN 45
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 714 ND Q P T IAVP P TA Q Q P PPT IPT MI A A A S PPSQP A V A LST I P G A VPI TPPI T --- TIAA APP PSVTVGGSLSSVLGPPV PEI 790
Cdd:pfam16014 46 SE Q Q T ASAS P PS Q H P AQA IPT IL A P A A PPSQP S V V LST L P A A MAV TPPI P asm ANVV APP TQPAASSTAACAVSSVL PEI 125
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 791 K V K E E V EPMD IMR pvs A VPPL ATNTV SP S L AL LANNLS M P TS DL P PGASPRKKPRKQQHVISTEEG D MMETNSTD D EKS T 870
Cdd:pfam16014 126 K I K Q E A EPMD TSQ --- S VPPL TPTSI SP A L TS LANNLS V P AG DL L PGASPRKKPRKQQHVISTEEG E MMETNSTD E EKS A 202
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 871 A K S L LVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK AM LQ EI ANQKGV S CR 950
Cdd:pfam16014 203 P K P L TSR AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK GT LQ DM ANQKGV T CR 282
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 951 AQGWK V HLCAAQLLQLTNLEHDVY E RLT N LQEG I IPKKKA A TDDDLHRINELIQGNMQRCKLVMDQI S EARDSM L KVLDH 1030
Cdd:pfam16014 283 AQGWK I HLCAAQLLQLTNLEHDVY S RLT T LQEG L IPKKKA G TDDDLHRINELIQGNMQRCKLVMDQI T EARDSM M KVLDH 362
....*....
gi 1057866215 1031 KDRVLKLLN 1039
Cdd:pfam16014 363 KDRVLKLLN 371
PHA03247
PHA03247 large tegument protein UL36; Provisional
536-885
3.04e-07
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 54.94
E-value: 3.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 536 P A P ISTQGIQ PA PIGT P GIQPA P L G T qgihs ATP I -- NTQGLQ P APM G TQQ P Q P ----- E G KTSAVVLADG A TIVANPI S 608
Cdd:PHA03247 2723 P G P AAARQAS PA LPAA P APPAV P A G P ----- ATP G gp ARPARP P TTA G PPA P A P paapa A G PPRRLTRPAV A SLSESRE S 2797
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 609 N P FSAA PA ATTVVQTHSQS A -- STNA PA QGSS P RP S ILRKK P AT dgmavrk TLI PP Q P PDV ---- AS P RVESSM R ST S G S 682
Cdd:PHA03247 2798 L P SPWD PA DPPAAVLAPAA A lp PAAS PA GPLP P PT S AQPTA P PP ------- PPG PP P P SLP lggs VA P GGDVRR R PP S R S 2870
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 683 P RPAG A K P KSEIHVSM A T P VT vsme TV S NQNNDQ P TIAVPPTA Q QPP P TI P TMIAAAS PP S QP AVALSTI P GAV P ITP P I 762
Cdd:PHA03247 2871 P AAKP A A P ARPPVRRL A R P AV ---- SR S TESFAL P PDQPERPP Q PQA P PP P QPQPQPP PP P QP QPPPPPP P RPQ P PLA P T 2946
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 763 T TI A A A PP PS VT V GGSLSSV L G P --- P VP EIK V KEEVEPMDI mr P V S AV PPL a T NTVSPSLALL A NN L SMPTSDL PP GA S 839
Cdd:PHA03247 2947 T DP A G A GE PS GA V PQPWLGA L V P grv A VP RFR V PQPAPSREA -- P A S ST PPL - T GHSLSRVSSW A SS L ALHEETD PP PV S 3023
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1057866215 840 prkkp R KQ QHVIS -- TE EG D MMETNST D D E K S TAKS L LVKAEKRKS P P 885
Cdd:PHA03247 3024 ----- L KQ TLWPP dd TE DS D ADSLFDS D S E R S DLEA L DPLPPEPHD P F 3066
PHA03247
PHA03247 large tegument protein UL36; Provisional
626-844
3.76e-06
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 51.48
E-value: 3.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 626 QSASTNA P AQGSS P R P SILRKK PA TD --- GMAVRKTLI P PQ P P D VAS P RVE S SM R STSGSP R P A G A KPKSEIHVSM A TPV 702
Cdd:PHA03247 2611 PAPPSPL P PDTHA P D P PPPSPS PA AN epd PHPPPTVPP P ER P R D DPA P GRV S RP R RARRLG R A A Q A SSPPQRPRRR A ARP 2690
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 703 TV SME T VSNQNNDQ P ------------ TIAV PP TAQQPPPTI P TMI AA AS PP SQ PA VALSTIPG A V P IT PP I T TIAA AP - 769
Cdd:PHA03247 2691 TV GSL T SLADPPPP P ptpepaphalvs ATPL PP GPAAARQAS P ALP AA PA PP AV PA GPATPGGP A R P AR PP T T AGPP AP a 2770
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1057866215 770 PP SVTVG G SLSSVLG P P V PEIKVKE E VE P MDIMRPVSAVPP LA TNTVS P SL A LL A NN L SM PTS DL P PGAS P RKK P 844
Cdd:PHA03247 2771 PP AAPAA G PPRRLTR P A V ASLSESR E SL P SPWDPADPPAAV LA PAAAL P PA A SP A GP L PP PTS AQ P TAPP P PPG P 2845
Atrophin-1
pfam03154 Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
439-820
7.17e-05
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain]
Cd Length: 991
Bit Score: 47.07
E-value: 7.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 439 P N P VAM E TR SD NRPSVPVQFQYFLPTYPP S AYPLAAHTYT P I T SSVS T IRQY P VSAQA P NSAIT A QTGVGVASTVHLN P M 518
Cdd:pfam03154 149 P S P QDN E SD SD SSAQQQILQTQPPVLQAQ S GAASPPSPPP P G T TQAA T AGPT P SAPSV P PQGSP A TSQPPNQTQSTAA P H 228
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 519 Q L MTVDAS ha R H I Q GI q P A P ISTQGIQPA P IGTPGIQ P A PL GTQGI H SAT P INTQG LQ PA P MGT Q Q P Q P E gktsavvlad 598
Cdd:pfam03154 229 T L IQQTPT -- L H P Q RL - P S P HPPLQPMTQ P PPPSQVS P Q PL PQPSL H GQM P PMPHS LQ TG P SHM Q H P V P P ---------- 295
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 599 g ATIVAN P I S NPFSAA P AATTVVQTH SQ SASTNA P A Q GSSPRPSIL R KK P ATDGMAVRKTLI PP --------------- Q 663
Cdd:pfam03154 296 - QPFPLT P Q S SQSQVP P GPSPAAPGQ SQ QRIHTP P S Q SQLQSQQPP R EQ P LPPAPLSMPHIK PP pttpipqlpnpqshk H 374
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 664 PP DVAS P rve S SMRST S GS P R P AGA KP K S EI --- H VSM A T P VTVSMETV S N Q ---- NNDQ P TIAVPPTAQQ P PPTI P TMI 736
Cdd:pfam03154 375 PP HLSG P --- S PFQMN S NL P P P PAL KP L S SL sth H PPS A H P PPLQLMPQ S Q Q lppp PAQP P VLTQSQSLPP P AASH P PTS 451
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 737 AAASP PSQ PAVAL - STI PG AV P - ITPP ITTIAAAPP ---------- P SV TVG G SLSSVLGP P V P EIKV KEE v EPMDIMR P 804
Cdd:pfam03154 452 GLHQV PSQ SPFPQ h PFV PG GP P p ITPP SGPPTSTSS ampgiqppss A SV SSS G PVPAAVSC P L P PVQI KEE - ALDEAEE P 530
410
....*....|....*.
gi 1057866215 805 V S AV PP LATNTVS P SL 820
Cdd:pfam03154 531 E S PP PP PRSPSPE P TV 546
PHA03247
PHA03247 large tegument protein UL36; Provisional
19-396
2.23e-04
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 45.70
E-value: 2.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 19 A PS QIANSGSAGLIN P AATVND E SG RD SEVSA R EHMSSSSSLQS R EEKQEPVVV RP YPQVQMLSTHHAVAS A T P VAVTAP 98
Cdd:PHA03247 2628 P PS PSPAANEPDPHP P PTVPPP E RP RD DPAPG R VSRPRRARRLG R AAQASSPPQ RP RRRAARPTVGSLTSL A D P PPPPPT 2707
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 99 P AHLTP A VPLSFSEGLMKPPPKPTM P SR P I APAPP STLS l P P KV PG QVTVTMESSIPQASAI P VATISGQQ G H P SN L HHI 178
Cdd:PHA03247 2708 P EPAPH A LVSATPLPPGPAAARQAS P AL P A APAPP AVPA - G P AT PG GPARPARPPTTAGPPA P APPAAPAA G P P RR L TRP 2786
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 179 MTTNVQM S IIRSNA P GP P LHIG A SH L PR gaaaaavms SSKVTTVLR P TSQ LP NAAT AQP AVQHIIHQ P IQSRP P VTT S N A 258
Cdd:PHA03247 2787 AVASLSE S RESLPS P WD P ADPP A AV L AP --------- AAALPPAAS P AGP LP PPTS AQP TAPPPPPG P PPPSL P LGG S V A 2857
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 259 -------- I P PAVV A TVS A TR A QS PV ITTTA --- AHA T D S ALR P TLSIQH PP SAAISIQRPA Q SRDVTTRITL P SH P ALG 327
Cdd:PHA03247 2858 pggdvrrr P P SRSP A AKP A AP A RP PV RRLAR pav SRS T E S FAL P PDQPER PP QPQAPPPPQP Q PQPPPPPQPQ P PP P PPP 2937
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1057866215 328 T P KQQ L HTMAQKTIFSTGTPVAAATVAPI L ATNTIP ----- SATT A G S VSHTQAP T STIVTMTVPSH SS H A TAV 396
Cdd:PHA03247 2938 R P QPP L APTTDPAGAGEPSGAVPQPWLGA L VPGRVA vprfr VPQP A P S REAPASS T PPLTGHSLSRV SS W A SSL 3011
PHA03247
PHA03247 large tegument protein UL36; Provisional
98-491
2.70e-04
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 45.31
E-value: 2.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 98 PP AH L T PA --------- VP LSFSEGLMKP P PKPTMPS RP I AP APPSTLSL P PKVP G QVTVTMES S - I P QASAI P VATISG 167
Cdd:PHA03247 2551 PP PP L P PA appaapdrs VP PPRPAPRPSE P AVTSRAR RP D AP PQSARPRA P VDDR G DPRGPAPP S p L P PDTHA P DPPPPS 2630
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 168 QQGHPSNLHHIMTTN V QMSIIRSNA P G P P ------------ LHIG AS HL P RGAAAA A VMSS - SKV T TVLR P TSQL P NAAT 234
Cdd:PHA03247 2631 PSPAANEPDPHPPPT V PPPERPRDD P A P G rvsrprrarrlg RAAQ AS SP P QRPRRR A ARPT v GSL T SLAD P PPPP P TPEP 2710
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 235 A QP A VQHIIHQ P I ------ Q SR P PVTTSN A I P PAVVATV --- SAT R AQS P VI T TTAAHATDS A LRPT lsiq H PP SAA isi 305
Cdd:PHA03247 2711 A PH A LVSATPL P P gpaaar Q AS P ALPAAP A P P AVPAGPA tpg GPA R PAR P PT T AGPPAPAPP A APAA ---- G PP RRL --- 2783
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 306 Q RPA QSRDVTT R IT LPS ------ H PA LGTPKQQLHTM A QKTIFSTGT P VA A ATV AP ILATNTI P SATTA G SVSHTQAP ts 379
Cdd:PHA03247 2784 T RPA VASLSES R ES LPS pwdpad P PA AVLAPAAALPP A ASPAGPLPP P TS A QPT AP PPPPGPP P PSLPL G GSVAPGGD -- 2861
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 380 ti V TMTV PS H S SH A TAVTTSNI PV AKV vpqqithts P R IQPDYPA E RSS L I P ISGH R ASPNPVAMETRSDNR P SV P V Q F Q 459
Cdd:PHA03247 2862 -- V RRRP PS R S PA A KPAAPARP PV RRL --------- A R PAVSRST E SFA L P P DQPE R PPQPQAPPPPQPQPQ P PP P P Q P Q 2930
410 420 430
....*....|....*....|....*....|..
gi 1057866215 460 YFL P TY P PSAY PLA AH T YTPITSSV S TIRQY P 491
Cdd:PHA03247 2931 PPP P PP P RPQP PLA PT T DPAGAGEP S GAVPQ P 2962
PRK07764
PRK07764 DNA polymerase III subunits gamma and tau; Validated
250-656
1.59e-03
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain]
Cd Length: 824
Bit Score: 42.67
E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 250 R PPVTTSN A IP PA VV A TVS A TR A QSPVITTT AA HATDS A LRPTLSIQH P PS A AISIQR P AQSRDVTTRITL PS H P ALGT P 329
Cdd:PRK07764 383 R RLGVAGG A GA PA AA A PSA A AA A PAAAPAPA AA APAAA A APAPAAAPQ P AP A PAPAPA P PSPAGNAPAGGA PS P P PAAA P 462
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 330 KQ Q LHTMAQKTIFS T GT P VA A ATV AP il A TNTI P S A TT A GSVSHTQAPTS T I ------ VTMT VP SH S SHAT A VTTSNIP V 403
Cdd:PRK07764 463 SA Q PAPAPAAAPEP T AA P AP A PPA AP -- A PAAA P A A PA A PAAPAGADDAA T L rerwpe ILAA VP KR S RKTW A ILLPEAT V 540
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 404 AK V VPQQ -- ITHTSP ---- R I - Q P DYPAE - RSS L IPIS G HRASPNP V AMETRSDNRPSV P VQFQYFL P TYP --- P S A YPL 472
Cdd:PRK07764 541 LG V RGDT lv LGFSTG glar R F a S P GNAEV l VTA L AEEL G GDWQVEA V VGPAPGAAGGEG P PAPASSG P PEE aar P A A PAA 620
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 473 A A HTYT P ITSSVSTIRQYPVS A Q AP NS A ITAQTGVG VA ST vhl NPMQLMTVDASH A RHIQGIQ P A P ISTQGIQP AP I G TP 552
Cdd:PRK07764 621 P A APAA P APAGAAAAPAEASA A P AP GV A APEHHPKH VA VP --- DASDGGDGWPAK A GGAAPAA P P P APAPAAPA AP A G AA 697
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 553 GI QPAP LGTQGIHSATPINTQGLQ P APMGTQQPQPEGKTSA V V L ADGAT iv AN P ISNPFS A A P AATTVVQTHSQS A STNA 632
Cdd:PRK07764 698 PA QPAP APAATPPAGQADDPAAQP P QAAQGASAPSPAADDP V P L PPEPD -- DP P DPAGAP A Q P PPPPAPAPAAAP A AAPP 775
410 420
....*....|....*....|....
gi 1057866215 633 P AQG S SPRPSILRKK P AT D GMAV R 656
Cdd:PRK07764 776 P SPP S EEEEMAEDDA P SM D DEDR R 799
PTZ00449
PTZ00449 104 kDa microneme/rhoptry antigen; Provisional
629-863
3.55e-03
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain]
Cd Length: 943
Bit Score: 41.60
E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 629 S TNA P AQGS SP RPSI L RKK P ATDGMAVRKT -- LI PP Q P PDVA SP RVESSMRSTSGSPR P AGA KP ------ K SEIHVSMAT 700
Cdd:PTZ00449 602 S AQR P TRPK SP KLPE L LDI P KSPKRPESPK sp KR PP P P QRPS SP ERPEGPKIIKSPKP P KSP KP pfdpkf K EKFYDDYLD 681
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 701 PVTV S M ET VSNQNN D QPTIAVPPTAQQPP P TI P TMIAAAS PP SQ P AVALS tipgav P IT P PITTI A AA P PP svtvggsl S 780
Cdd:PTZ00449 682 AAAK S K ET KTTVVL D ESFESILKETLPET P GT P FTTPRPL PP KL P RDEEF ------ P FE P IGDPD A EQ P DD -------- I 747
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 781 SVLG PP VP E - IKVK E --- EVEPM DI MRPVSAVPPLATN T VS P SL A LLANNLSMPTS D L PPG --- AS P R K KP R KQQHVI ST 853
Cdd:PTZ00449 748 EFFT PP EE E r TFFH E tpa DTPLP DI LAEEFKEEDIHAE T GE P DE A MKRPDSPSEHE D K PPG dhp SL P K K RH R LDGLAL ST 827
250
....*....|
gi 1057866215 854 EE gdm M E TNS 863
Cdd:PTZ00449 828 TD --- L E SDA 834
PRK07003
PRK07003 DNA polymerase III subunit gamma/tau;
555-778
7.27e-03
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain]
Cd Length: 830
Bit Score: 40.22
E-value: 7.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 555 Q PA PL G TQGIHSAT P INTQ G LQ PAP mgtqqpqpegkts AVVL A DGATIV A N P ISNPFSA A PA A TTVVQTHSQS A S T N A P A 634
Cdd:PRK07003 359 E PA VT G GGAPGGGV P ARVA G AV PAP ------------- GARA A AAVGAS A V P AVTAVTG A AG A ALAPKAAAAA A A T R A E A 425
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1057866215 635 QGSS P R P silrkk PAT DGMAVRKTLIPPQP P DV A SP R VESSM R STSGSPR P A g A KPK S EIHVSMAT P VTVSM E tvsnqnn 714
Cdd:PRK07003 426 PPAA P A P ------ PAT ADRGDDAADGDAPV P AK A NA R ASADS R CDERDAQ P P - A DSG S ASAPASDA P PDAAF E ------- 491
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1057866215 715 DQ P TI A V P PT A QQPPPTIPTMI AAAS PPSQ PA V A LSTI P G A V P I TP pitti AAA P P PSVTV G GS 778
Cdd:PRK07003 492 PA P RA A A P SA A TPAAVPDARAP AAAS REDA PA A A APPA P E A R P P TP ----- AAA A P AARAG G AA 550
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
