|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
1-554 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1067.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 1 MAALTRDPQFQKLQQWYREHRsELNLRRLFDANKDRFNHFSLTLntnhGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAA 80
Cdd:PRK00179 2 NINLTQTPAWQALQAHADEIK-DVHLRDLFAADPDRFERFSLTA----GGLLLDYSKNRITDETLALLLDLAREAGLEGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 81 RERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGS 160
Cdd:PRK00179 77 RDAMFAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 161 DLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVA 240
Cdd:PRK00179 157 DLGPVMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 241 KHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLL 320
Cdd:PRK00179 237 KHFVAVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 321 ALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTK 400
Cdd:PRK00179 317 ALIGVWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTK 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 401 MIPCDFLIPVQTQHPIRKglHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFT 480
Cdd:PRK00179 397 LVPADFIAPAQPHNPLGD--HHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLD 474
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1049480200 481 KLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQRE 554
Cdd:PRK00179 475 RLTPFTLGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
54-546 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 971.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 54 DYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFC 133
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 134 QRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTF 213
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 214 TTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNF 293
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 294 EQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDH 373
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 374 QTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPiRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAg 453
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNP-ENGDHHKILLSNFFAQTEALMVGKSPEEVRKELAAA- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 454 kspeDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSA 533
Cdd:pfam00342 399 ----DVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSN 474
|
490
....*....|...
gi 1049480200 534 QVTSHDASTNGLI 546
Cdd:pfam00342 475 KVSSHDSSTNGLI 487
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
36-551 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 766.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 36 RFNHFSLTLntnhGHILVDYSKNLVTEDVMRMLVDLAKSrgvEAARERMFNGEKINYTEGRAVLHVALRNRSntpilvDG 115
Cdd:COG0166 12 RFERFSLEA----AGLLLDYSKNRITDETLELLLELAEE---EEAREALFAGEKINPTEGRAVLHGALRLPE------AG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 116 KDVMPEVNKVLDKMKSFCQRVRsgdwkgyTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKT 195
Cdd:COG0166 79 EDVMPEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYFRDGPRVHFVSNVDPDYLAEL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 196 LAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDpsAVAKHFVALSTNTTKVKEFGIDP-QNMFEFWDWVGGRY 274
Cdd:COG0166 152 LAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGE--DAAKHFVAVTDNAGALRAFGIDEgYNTFPFPDWVGGRY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 275 SLWSAIGLSIALHVGFDnFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQ 354
Cdd:COG0166 230 SVLSAVGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFPAWLQQ 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 355 GDMESNGKYITKSGTRVDHQTGPIvwGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIrkglhHKILLANFlaQTE 434
Cdd:COG0166 309 LWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDI-----PDLLLANL--QGL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 435 ALMRGKSTEEARK-ELQAAgkspedlerllPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQW 513
Cdd:COG0166 380 ALLAGKTLDEVLAlAAEAT-----------PHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQP 448
|
490 500 510
....*....|....*....|....*....|....*...
gi 1049480200 514 GVELGKQLAKKIEPELDGSAQVTshDASTNGLINFIKQ 551
Cdd:COG0166 449 GVELGKKLAFALLGKLGGEEAAA--GDSTEALLKRLRA 484
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
334-525 |
2.23e-91 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 277.56 E-value: 2.23e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 334 ETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTrvDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQ 413
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGE--DYPTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 414 H----PIRKGLHHKILLANFLAQTEALMrgksteearkelqaagkspedlerllphkvFEGNRPTNSIVFTKLTPFMLGA 489
Cdd:cd05016 79 NdvldYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 1049480200 490 LVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKI 525
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pgi |
PRK00179 |
glucose-6-phosphate isomerase; Reviewed |
1-554 |
0e+00 |
|
glucose-6-phosphate isomerase; Reviewed
Pssm-ID: 234679 Cd Length: 548 Bit Score: 1067.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 1 MAALTRDPQFQKLQQWYREHRsELNLRRLFDANKDRFNHFSLTLntnhGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAA 80
Cdd:PRK00179 2 NINLTQTPAWQALQAHADEIK-DVHLRDLFAADPDRFERFSLTA----GGLLLDYSKNRITDETLALLLDLAREAGLEGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 81 RERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGS 160
Cdd:PRK00179 77 RDAMFAGEKINTTEDRAVLHTALRNPSNTPILVDGQDVMPEVHAVLARMKAFAEAVRSGEWKGYTGKAITDVVNIGIGGS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 161 DLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPSAVA 240
Cdd:PRK00179 157 DLGPVMVTEALRPYADPGLRVHFVSNVDGAHLAETLKKLDPETTLFIVASKTFTTQETLTNAHSARDWFLAAGGDEAAVA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 241 KHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVLL 320
Cdd:PRK00179 237 KHFVAVSTNAEAVAEFGIDPDNMFGFWDWVGGRYSLWSAIGLSIALAIGPDNFEELLAGAHAMDEHFRTAPLEKNLPVLL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 321 ALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGTK 400
Cdd:PRK00179 317 ALIGVWYRNFFGAQSHAVLPYDQYLHRFPAYLQQLEMESNGKSVDRDGTPVDYQTGPIIWGEPGTNGQHAFFQLLHQGTK 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 401 MIPCDFLIPVQTQHPIRKglHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPEDLERLLPHKVFEGNRPTNSIVFT 480
Cdd:PRK00179 397 LVPADFIAPAQPHNPLGD--HHDLLLANCFAQTEALMFGKTAEEVRAELRAKGLDEAEAEELAPHKVFPGNRPSTTILLD 474
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1049480200 481 KLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVTSHDASTNGLINFIKQQRE 554
Cdd:PRK00179 475 RLTPFTLGALIALYEHKVFVQGVIWGINSFDQWGVELGKQLAKRILPELEGDSEASAHDSSTNGLINRYRAWRG 548
|
|
| PGI |
pfam00342 |
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of ... |
54-546 |
0e+00 |
|
Phosphoglucose isomerase; Phosphoglucose isomerase catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate.
Pssm-ID: 395271 Cd Length: 487 Bit Score: 971.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 54 DYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFC 133
Cdd:pfam00342 1 DYSKNHINDEILTALVKLAEERGVDAAREAMFNGEKINSTENRAVLHVALRNRSNTPIYVDGKDVMPEVNAVLAKMKSFS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 134 QRVRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTF 213
Cdd:pfam00342 81 ERVRSGEWKGYTGKAITDVVNIGIGGSDLGPVMVTEALKPYSGRDLDVHFVSNVDGTHIAEVLKKLNPETTLFIVASKTF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 214 TTQETITNAETAKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDNF 293
Cdd:pfam00342 161 TTAETMTNAESAKEWLLKALKDDSAVAKHFIALSTNAEKVEEFGIDTKNMFEFWDWVGGRYSLWSAIGLPIALSIGFENF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 294 EQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDH 373
Cdd:pfam00342 241 QQLLEGAHAMDKHFLSAPPEKNIPVLLALLGVWYNNFFGAQTHAILPYDQYLHRFPAYLQQLDMESNGKYVTRDGVLVDH 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 374 QTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPiRKGLHHKILLANFLAQTEALMRGKSTEEARKELQAAg 453
Cdd:pfam00342 321 QTGPIIFGEPGTNGQHAFYQLIHQGTRLIPCDFIGAVQSQNP-ENGDHHKILLSNFFAQTEALMVGKSPEEVRKELAAA- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 454 kspeDLERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSA 533
Cdd:pfam00342 399 ----DVEHLIPHKTFTGNRPSNSILVQKLTPATLGALIAMYEHKIFVQGAIWGINSFDQWGVELGKVLAKSILPELENSN 474
|
490
....*....|...
gi 1049480200 534 QVTSHDASTNGLI 546
Cdd:pfam00342 475 KVSSHDSSTNGLI 487
|
|
| Pgi |
COG0166 |
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate ... |
36-551 |
0e+00 |
|
Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Glucose-6-phosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439936 Cd Length: 484 Bit Score: 766.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 36 RFNHFSLTLntnhGHILVDYSKNLVTEDVMRMLVDLAKSrgvEAARERMFNGEKINYTEGRAVLHVALRNRSntpilvDG 115
Cdd:COG0166 12 RFERFSLEA----AGLLLDYSKNRITDETLELLLELAEE---EEAREALFAGEKINPTEGRAVLHGALRLPE------AG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 116 KDVMPEVNKVLDKMKSFCQRVRsgdwkgyTGKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKT 195
Cdd:COG0166 79 EDVMPEVREELARIKAFAEKVR-------TGKRITDVVNIGIGGSDLGPRAVIEALKPYFRDGPRVHFVSNVDPDYLAEL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 196 LAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDpsAVAKHFVALSTNTTKVKEFGIDP-QNMFEFWDWVGGRY 274
Cdd:COG0166 152 LAGLDPETTLFIVISKSGTTQETLTNARVAREWLEKAGGE--DAAKHFVAVTDNAGALRAFGIDEgYNTFPFPDWVGGRY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 275 SLWSAIGLSIALHVGFDnFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQ 354
Cdd:COG0166 230 SVLSAVGLLPAAAIGID-FEELLAGAHAMDEHFRTAPLEENPPVLLALLGIWYRNFKGAETEAVLPYDQRLERFPAWLQQ 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 355 GDMESNGKYITKSGTRVDHQTGPIvwGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIrkglhHKILLANFlaQTE 434
Cdd:COG0166 309 LWMESNGKSVDRDGNPVGYGTGPV--GEPGTTDQHSFGQLLHQGTRDIPVTFIAVAEPHHDI-----PDLLLANL--QGL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 435 ALMRGKSTEEARK-ELQAAgkspedlerllPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQW 513
Cdd:COG0166 380 ALLAGKTLDEVLAlAAEAT-----------PHALFPGNRPSNTILLPKLTPYTLGALIALYEHAVFVQGVLWGINPFDQP 448
|
490 500 510
....*....|....*....|....*....|....*...
gi 1049480200 514 GVELGKQLAKKIEPELDGSAQVTshDASTNGLINFIKQ 551
Cdd:COG0166 449 GVELGKKLAFALLGKLGGEEAAA--GDSTEALLKRLRA 484
|
|
| PLN02649 |
PLN02649 |
glucose-6-phosphate isomerase |
1-547 |
0e+00 |
|
glucose-6-phosphate isomerase
Pssm-ID: 215351 [Multi-domain] Cd Length: 560 Bit Score: 732.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 1 MAALTRDPQFQKLQQWYrEHRSELNLRRLFdANKDRFNHFSLTLNTnhghILVDYSKNLVTEDVMRMLVDLAKSRGVEAA 80
Cdd:PLN02649 5 TLLISDTPAWKRLVAHV-YQIKKTHLRELL-NDAERCQSMIAEFDG----IYLDYSRQRVTDETMELLFPLAEAANLFEK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 81 RERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGS 160
Cdd:PLN02649 79 IEAMFSGEIINSTEDRAVLHVALRAPRLAPILVDGKNVVPEVWEVLDKIKAFSEDVRSGKWKGATGKRFTNVVSIGIGGS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 161 DLGPLMVTEALKPY-----SSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAkD 235
Cdd:PLN02649 159 FLGPLFVHEALATDpealkSAKGRKLRFLANVDPVDIARQIAQLDPETTLVVVVSKTFTTAETMLNARTVRKWLRDAL-G 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 236 PSAVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIG-LSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEK 314
Cdd:PLN02649 238 GLAVAKHMVAVSTNLLLVNKFGIDPWNAFPFWDWVGGRYSVCSAVGlLPLSLQYGFDVVEEFLEGAASMDEHFRTAPLKE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 315 NAPVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQL 394
Cdd:PLN02649 318 NIPVLLGLLSVWNSSFLGYPARAILPYSQALLKFAPHIQQLDMESNGKGVDLDGNPLPVNTGEIDFGEPGTNGQHSFYQL 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 395 IHQGtKMIPCDFLIPVQTQHPIRKGL-----HHKILLANFLAQTEALMRGKSTEEARKElqaagkspEDLERLLPHKVFE 469
Cdd:PLN02649 398 IHQG-RNIPCDFIGVVRSQQPVHLWLgegvsNHDELMSNFFAQPDALAYGKTPEQLRAE--------GVPEELIPHKVFA 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 470 GNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGS----AQVTSHDASTNGL 545
Cdd:PLN02649 469 GNRPSLSILLPELTAYTVGQLLALYEHRVAVQGFIWNINSFDQWGVELGKALAKRVRAVLNEArtkgEPVEGFNSSTTAL 548
|
..
gi 1049480200 546 IN 547
Cdd:PLN02649 549 LN 550
|
|
| PTZ00430 |
PTZ00430 |
glucose-6-phosphate isomerase; Provisional |
3-525 |
0e+00 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 185612 Cd Length: 552 Bit Score: 613.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 3 ALTRDPQFQKLQQwYREHRSELNLRRLFDaNKDRFNHfsltLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARE 82
Cdd:PTZ00430 2 DLESLKSYKNLLS-LAEKLKKVHLRDLLK-DEERNKS----LIKEFKGVTLDLSRQRLDEETLKLLIELAEEAKLKEKIK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 83 RMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDVMPEVNKVLDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDL 162
Cdd:PTZ00430 76 DMFNGEKINTTENRAVLHTALRAPRGEKVVVDGKNVLEDVHEVLDRIKKFSDKIRSGEILGSTGKKLKNVICIGIGGSYL 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 163 GPLMVTEALKPYSSG-----GPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPS 237
Cdd:PTZ00430 156 GTEFVYEALRTYGEAreaskGRKLRFLANVDPIDVRRATEGLDPEETLVVIISKTFTTAETMLNAKTVRQWLLDNIKSKE 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 238 AVAKHFVALSTNTTKVKEFGIDPQNMFEFWDWVGGRYSLWSAIG-LSIALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNA 316
Cdd:PTZ00430 236 ALSKHLCAVSTNLKLTSEFGIPDENVFGFWDWVGGRFSVTSAVGiLPLSIQFGYDIVQQFLNGCHDMDEHFRTAPLEENL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 317 PVLLALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIH 396
Cdd:PTZ00430 316 PVLLGLTSFYNSTFLGYNCVAILPYCQALLKFPAHVQQLLMESNGKSVTLDGNTLDYNTGEIYFGEPGTNGQHSFYQLLH 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 397 QGTkMIPCDFLIPVQTQHPIRKG----LHHKILLANFLAQTEALMRGKSTEEARKElqaaGKSPEdlerLLPHKVFEGNR 472
Cdd:PTZ00430 396 QGR-VVPSEFIGFAKSQNPIKLLgepvSNHDELMSNFFAQPDALAFGKTYEELEKE----GVPEE----LIPHKVFPGNR 466
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 1049480200 473 PTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKI 525
Cdd:PTZ00430 467 PSLLLLFPELNPYTIGQLLALYEHRTVVEGFLWNINSFDQWGVELGKVLAKDV 519
|
|
| pgi |
PRK14095 |
glucose-6-phosphate isomerase; Provisional |
10-525 |
1.99e-143 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237608 Cd Length: 533 Bit Score: 424.43 E-value: 1.99e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 10 FQKLQQWyreHRSELNLRRLFDANKDRFNHFSLTLntnhGHILVDYSKNLVTEDVMRMLVDLAKSRGVEAARERMFNGEK 89
Cdd:PRK14095 13 FKILQEL---APEPLDLTLPGVLSEERIKKYSLSG----EGFTYNYATERVDDRILAALQNLADEAELIEKMKAMQNGAV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 90 INYTEG-----RAVLHVALRNRSNTPILVDGKDVMPEVNKV-LDKMKSFCQRVRSGDWKGYTGKTITDVINIGIGGSDLG 163
Cdd:PRK14095 86 INRIEGfpsenRPVLHTATRGQVGDSVLTDEAEDMAEFSKReLERLAEFLKKVRSGEIKNSNGKKFTTVVQIGIGGSDLG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 164 PLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAKEWFLQAAKDPsavAKHF 243
Cdd:PRK14095 166 PKALYLALKNYAKKDKRVHFISNVDPDDAAEVLSEIDLAKTLFIVVSKSGTTLETAANEEFVRDALKKAGLDY---KKHF 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 244 VALSTNTTKVKefgiDPQN---MFEFWDWVGGRYSLWSAIGLS-IALHVGFDNFEQLLSGAHWMDQHFRTTPLEKNAPVL 319
Cdd:PRK14095 243 IAVTSEGSPMD----DESGyleVFHMWDSIGGRFSSTSMVGGVvLGFAFGFEVFKEFLKGAAAMDKAALNPNIRENLPLL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 320 LALLGIWYINCFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVWGEPGTNGQHAFYQLIHQGT 399
Cdd:PRK14095 319 AALIGIWNRNFLGYPTTAVIPYSQALERFPAHLQQLDMESNGKSVNRFGEPINFKTGPIIWGEPGTNGQHSFFQLLHQGT 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 400 KMIPCDFLIPVQTQH----PIRKGLHHKILLANFLAQTEALMRGKSTEEarkelqaagkspedlerllPHKVFEGNRPTN 475
Cdd:PRK14095 399 DIVPVEFIGFKESQLgqdiVIQGSTSQQKLFANLIAQIIALACGKENTN-------------------PNKNFKGNRPSS 459
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 1049480200 476 SIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKI 525
Cdd:PRK14095 460 LLVAKQLTPYTLGALLAHYENKVMFQGFCWNINSFDQEGVQLGKVLANQI 509
|
|
| SIS_PGI_2 |
cd05016 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
334-525 |
2.23e-91 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240147 Cd Length: 164 Bit Score: 277.56 E-value: 2.23e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 334 ETHAMLPYDQYLHRFAAYFQQGDMESNGKYITKSGTrvDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQ 413
Cdd:cd05016 1 KTHALLPYSQRLERFPAWLQQLDMESNGKSVTRDGE--DYPTGPIPWGAPGTNDQHSFFQLIHQGTKDKPVDFIAVKKPQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 414 H----PIRKGLHHKILLANFLAQTEALMrgksteearkelqaagkspedlerllphkvFEGNRPTNSIVFTKLTPFMLGA 489
Cdd:cd05016 79 NdvldYLAGKTLHDLLLANCLATREALM------------------------------FPGGRPSNTIVLPELTPYTLGA 128
|
170 180 190
....*....|....*....|....*....|....*.
gi 1049480200 490 LVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKI 525
Cdd:cd05016 129 LLALYEHKTAVQGALLGINPFDQPGVELGKKLAKKI 164
|
|
| SIS_PGI_1 |
cd05015 |
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification ... |
123-286 |
1.16e-82 |
|
Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of glucose 6-phosphate to fructose 6-phosphate. As an extracellular protein, PGI also has functions equivalent to neuroleukin (NLK), autocrine motility factor (AMF), and maturation factor (MF). Evidence suggests that PGI, NLK, AMF, and MF are closely related or identical. NLK is a neurotrophic growth factor that promotes regeneration and survival of neurons. The dimeric form of NLK has isomerase function, whereas its monomeric form carries out neurotrophic activity. AMF is a cytokine that stimulates cell migration and metastasis. MF mediates the differentiation of human myeloid leukemic HL-60 cells to terminal monocytic cells.
Pssm-ID: 240146 Cd Length: 158 Bit Score: 254.76 E-value: 1.16e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 123 NKVLDKMKSFCQRVRSGdwkgytgKTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPE 202
Cdd:cd05015 1 RAELERIKEFAEKVRSG-------KKITDVVVIGIGGSDLGPRAVYEALKPYFKGGLRLHFVSNVDPDDLAELLKKLDPE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 203 SSLFIIASKTFTTQETITNAETAKEWFLQAAKDpsAVAKHFVALSTNTTKVKE-FGIDPQNMFEFWDWVGGRYS-LWSAI 280
Cdd:cd05015 74 TTLFIVISKSGTTLETLANARLAREWLEEAGGD--DLAKHFVAITDNGSGLLKkAGIEGLNTFEIPDWVGGRFSvLSSVG 151
|
....*.
gi 1049480200 281 GLSIAL 286
Cdd:cd05015 152 GLPLAL 157
|
|
| pgi |
PRK14096 |
glucose-6-phosphate isomerase; Provisional |
63-525 |
1.19e-50 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 237609 [Multi-domain] Cd Length: 528 Bit Score: 182.01 E-value: 1.19e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 63 DVMRMLVDLAKSRGVEAARERMF-------NGEKINYTEGRAVLHVALRNrsntPILVDGKDVMPEVNKVLDKMKSFCQR 135
Cdd:PRK14096 25 DISRMNFDDAFLESLEPKFQKAFaamaaleAGAIANPDEGRMVGHYWLRN----PELAPTPEIRAEITETLAQIEAFAAK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 136 VRSGDWKGYTGKTITDVINIGIGGSDLGPLMVTEALKPySSGGPRVWYVSNIDGTHIAKTLAQLNPE--SSLFIIASKTF 213
Cdd:PRK14096 101 VHSGTIKPPNGEKFTDVLWIGIGGSALGPQFVAEALQP-NSDGLNIHFIDNTDPDGIDRVLAELGDRlaTTLVVVISKSG 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 214 TTQETITNAETAKEWFLQAAKDpsaVAKHFVALSTNTTKVKEFGIDPQ--NMFEFWDWVGGRYSLWSAIGLSIALHVGFD 291
Cdd:PRK14096 180 GTPETRNGMLEAKAAYEAAGLD---FASHAVAITMKGSKLDQLAQSEGwlARFPMWDWVGGRTSETSAVGLLPAALQGID 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 292 NFEqLLSGAHWMDQHFRTTPLEKNAPVLLALLgiWYINCFGCETHAM--LPYDQYLHRFAAYFQQGDMESNGKYITKSGT 369
Cdd:PRK14096 257 IRA-FLAGAKQMDEATRVPDLKNNPAALLALA--WYYAGDGKGKKDMvvLPYKDRLLLFSRYLQQLVMESLGKELDLDGN 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 370 RVdHQtGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFL----IPVQTQHPIRKGLHHKILLANFLAQT-EALmrgkstee 444
Cdd:PRK14096 334 VV-HQ-GIAVYGNKGSTDQHAYVQQLRDGVDNFFVTFIevleDRQGSSIEVEPGVTSGDYLSGFLQGTrQAL-------- 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 445 arkelqaagkspedlerllphkvFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKK 524
Cdd:PRK14096 404 -----------------------YENGRQSITITIPEVNPRTLGALIALFERAVGLYASLVNINAYHQPGVEAGKKAAAA 460
|
.
gi 1049480200 525 I 525
Cdd:PRK14096 461 I 461
|
|
| PRK00973 |
PRK00973 |
glucose-6-phosphate isomerase; Provisional |
147-522 |
1.25e-37 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 179193 [Multi-domain] Cd Length: 446 Bit Score: 144.37 E-value: 1.25e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 147 KTITDVINIGIGGSDLGPLMVTEALKPYSS--------GGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQET 218
Cdd:PRK00973 69 KNFDNVVVLGIGGSALGNLALHYALNPLNWnelskeerNGPRVFVLDNVDPEKTASILDVIDLEKTLFNVISKSGNTAET 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 219 ITNAETAKEWFLQAAKDPSavaKHFVALsTNTTK------VKEFGID----PQNmfefwdwVGGRYSLWSAIGLSIALHV 288
Cdd:PRK00973 149 LANYLIIRGILEKLGLDPK---KHLVFT-TDPEKgklkkiAEKEGYRtleiPEN-------VGGRFSVLTPVGLAPAAAL 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 289 GFDnFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINcFGCETHAMLPYDQYLHRFAAYFQQGDMESNGKyitksg 368
Cdd:PRK00973 218 GID-IEELLEGAKEMDKICEKEDIFKNPALLNALIHYLYYN-RGKNISVMMPYSERLKYFGDWYRQLWAESLGK------ 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 369 tRVDHQTgPIvwGEPGTNGQHAFYQLIHQG--TKMI--------PCDFLIPvqTQHPIRKGLHH---KILlaNFLAQTEA 435
Cdd:PRK00973 290 -KGVGQT-PV--KALGATDQHSQLQLYMEGpkDKIItflkvekyRRDVEIP--YEYEDIEELSYlggHKL--SELINSEQ 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 436 lmrgKSTEEARKelqaagkspedlerllphkvfEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGV 515
Cdd:PRK00973 362 ----KGTEIALT---------------------ENGRPNVKITLDELNEYTVGQLFYMYEMQTAFMGELLNINAFDQPGV 416
|
....*..
gi 1049480200 516 ELGKQLA 522
Cdd:PRK00973 417 ELGKKIT 423
|
|
| PRK03868 |
PRK03868 |
glucose-6-phosphate isomerase; Provisional |
147-525 |
2.87e-27 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 235168 Cd Length: 410 Bit Score: 113.88 E-value: 2.87e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 147 KTITDVINIGIGGSDLGPLMVTEALKPYSSGGPRVWYVSNIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAETAK 226
Cdd:PRK03868 56 ESIKNIVVIGIGGSSLGVKAIYSFLKNEKNNKKELHFLENTDPISINKTLSKINLENTLFIVISKSGTTIETISIFKYLL 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 227 EWF--LQAAK-------DPSAVAKHFvalsTNTTKVKEFGIdPQNmfefwdwVGGRYSLWSAIG---LSIAlhvGFDnFE 294
Cdd:PRK03868 136 SHFklDQELKknflfitDPDSKLEQF----AKENNIKCFNI-PKN-------VGGRFSVLSAVGivpLALC---GYD-IK 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 295 QLLSGAHWMDQHFrttpLEKNAPVLL--ALLGIWYINCFgcETHAMLPYDQYLHRFAAYFQQGDMESNGKyITKSGTRVd 372
Cdd:PRK03868 200 ALLEGAKACKDSF----FEQKEDHILkkAYFYATHKNAY--NINVLFSYSDALKGFNDWYVQLWGESLGK-KQGYKTRV- 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 373 hqtGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIR------KGLhHKILLANFLAQTEAL-MRGKSTEEA 445
Cdd:PRK03868 272 ---GLTPIGLIGSRDQHSFLQLIMEGPRDKTVTFIKIKDFQNAPKipnislKGL-ESLDFVNGVSFNELInAQCDATMEA 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 446 RKElqaagkspEDLerllphkvfegnrPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWGVELGKQLAKKI 525
Cdd:PRK03868 348 LIA--------EDI-------------PVDVITLEKLDEFSIGYLIYYYELLTSAVGKMLGINTYDQPGVEVGKRILKEK 406
|
|
| pgi |
PRK14097 |
glucose-6-phosphate isomerase; Provisional |
150-520 |
9.12e-11 |
|
glucose-6-phosphate isomerase; Provisional
Pssm-ID: 184504 Cd Length: 448 Bit Score: 64.09 E-value: 9.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 150 TDVINIGIGGSDLGPLMVTEAL--------KPYSSGGPRVWYVSN-IDGTHIAKTLAQL-NPESSLFIIaSKTFTTQET- 218
Cdd:PRK14097 74 DVLVVIGIGGSYLGARAAIEFLnhsfynllPKEQRKAPQIIFAGNsISSTYLADLLEYLkDKDFSINVI-SKSGTTTEPa 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 219 ----ITNAETAKEWFLQAAKdpsavaKHFVAlSTNTTK--VKEFGiDPQN--MFEFWDWVGGRYSLWSAIGLSIALHVGF 290
Cdd:PRK14097 153 iafrIFKELLEKKYGKEEAK------KRIYA-TTDKAKgaLKTLA-DAEGyeTFVIPDDVGGRFSVLTAVGLLPIAVAGI 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 291 DnFEQLLSGAHWMDQHFRTTPLEKNAPVLLALLGIWYINcFGCETHAMLPYDQYLHRFAAYFQQGDMESNGK-----YIT 365
Cdd:PRK14097 225 D-IDALMKGAADARKDYSSSDLSENPAYQYAAVRNILYR-KGYTTEILVNYEPSLQYFSEWWKQLFGESEGKdqkgiFPA 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 366 KSGTRVD-HQTGpivwgepgtngqhafyQLIHQGTKMIpcdFLIPVQTQHPirkglHHKILLA---------NFLAqtea 435
Cdd:PRK14097 303 SANFSTDlHSLG----------------QYIQEGRRNL---FETVIKVEKP-----RKDLTIPedeedldglNYLA---- 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 436 lmrGKSTEEA-RKELQAAgkspedlerLLPHkvFEGNRPTNSIVFTKLTPFMLGALVAMYEHKIFVQGIIWDINSFDQWG 514
Cdd:PRK14097 355 ---GKTVDFVnKKAFEGT---------LLAH--TDGGVPNIVVNIPELDEYTFGYLVYFFEKACAISGYLLGVNPFDQPG 420
|
....*.
gi 1049480200 515 VELGKQ 520
Cdd:PRK14097 421 VEAYKK 426
|
|
| PRK09533 |
PRK09533 |
bifunctional transaldolase/phosoglucose isomerase; Validated |
126-303 |
1.53e-10 |
|
bifunctional transaldolase/phosoglucose isomerase; Validated
Pssm-ID: 236551 [Multi-domain] Cd Length: 948 Bit Score: 64.22 E-value: 1.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 126 LDKMKSFCQRVRSGDwkgytgktITDVINIGIGGSDLGPlmvtEALK---PYSSGGPRVwYVsnIDGTHIAKTLA---QL 199
Cdd:PRK09533 440 LAEYEAFAEEVRAEG--------FTDAVVLGMGGSSLGP----EVLAetfGQRDGFPKL-HV--LDSTDPAQVRAleaAV 504
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 200 NPESSLFIIASKTFTTQEtiTNAetAKEWFLQAAKDP--SAVAKHFVALS---TNTTKVKE-------FGIDPQnmfefw 267
Cdd:PRK09533 505 DLARTLFIVSSKSGGTLE--PNI--FKDYFFARVKEVlgAKAGRHFVAVTdpgSSLEKVAKedgfrkiFHGDPD------ 574
|
170 180 190
....*....|....*....|....*....|....*.
gi 1049480200 268 dwVGGRYSLWSAIGLSIALHVGFDnFEQLLSGAHWM 303
Cdd:PRK09533 575 --IGGRYSVLSPFGLVPAAAAGID-VRALLDSALAM 607
|
|
| SIS |
cd04795 |
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
344-436 |
1.09e-03 |
|
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240112 [Multi-domain] Cd Length: 87 Bit Score: 38.12 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1049480200 344 YLHRFAAYFQQGDMESngkyitksgtrvdhqTGPIVWGEPGTNGQHAFyqLIHQGTKMIPCDFLIPVQTQhpirkglhhk 423
Cdd:cd04795 8 GSGAIAAYFALELLEL---------------TGIEVVALIATELEHAS--LLSLLRKGDVVIALSYSGRT---------- 60
|
90
....*....|...
gi 1049480200 424 ILLANFLAQTEAL 436
Cdd:cd04795 61 EELLAALEIAKEL 73
|
|
| SIS_1 |
cd05710 |
A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar ... |
155-227 |
7.35e-03 |
|
A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240214 [Multi-domain] Cd Length: 120 Bit Score: 36.79 E-value: 7.35e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1049480200 155 IGIGGSdLGPLM-VTEALKPYSSggpRVWYVSNidgthiAKTLAQLNP----ESSLFIIASKTFTTQETITNAETAKE 227
Cdd:cd05710 5 VGCGGS-LADMYpAKYFLKKESK---LPVFVYN------AAEFLHTGPkrltEKSVVILASHSGNTKETVAAAKFAKE 72
|
|
| |
